MCID: APR002
MIFTS: 23

Aip-Related Familial Isolated Pituitary Adenomas malady

Genetic diseases, Rare diseases, Gastrointestinal diseases categories

Summaries for Aip-Related Familial Isolated Pituitary Adenomas

About this section
Sources:
20GeneReviews, 34MalaCards
See all sources

Fully expand this MalaCard

Download this MalaCard
MalaCards: Aip-Related Familial Isolated Pituitary Adenomas, also known as pituitary adenoma predisposition, is related to pituitary adenoma and adenoma. An important gene associated with Aip-Related Familial Isolated Pituitary Adenomas is AIP (aryl hydrocarbon receptor interacting protein). The compounds octreotide and acth have been mentioned in the context of this disorder. Affiliated tissues include pituitary, and related mouse phenotypes are growth/size/body and endocrine/exocrine gland.

GeneReviews summary for ipa

Aliases & Classifications for Aip-Related Familial Isolated Pituitary Adenomas

About this section
Sources:
20GeneReviews, 21GeneTests, 63UMLS
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

aip-related familial isolated pituitary adenomas 20 21
pituitary adenoma predisposition 63


Related Diseases for Aip-Related Familial Isolated Pituitary Adenomas

About this section
Sources:
18GeneCards, 19GeneDecks
See all sources

Diseases in the Familial Isolated Pituitary Adenoma family:

aip-related familial isolated pituitary adenomas

Diseases related to Aip-Related Familial Isolated Pituitary Adenomas via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 11)
idRelated DiseaseScoreTop Affiliating Genes
1pituitary adenoma30.6AIP, SSTR5, GNAS
2adenoma30.5AIP, GNAS, SSTR5
3familial isolated pituitary adenoma10.5
4osteomalacia10.1GNAS
5pheochromocytoma10.0GNAS, SSTR5
6gigantism10.0AIP, GNAS
7carney complex10.0GNAS, AIP
8carcinoid syndrome10.0SSTR5, GNAS
9acromegaly9.9SSTR5, GNAS, AIP
10prolactinoma9.9SSTR5, GNAS, AIP
11pituitary tumors9.9SSTR5, AIP, GNAS

Graphical network of diseases related to Aip-Related Familial Isolated Pituitary Adenomas:



Diseases related to aip-related familial isolated pituitary adenomas

Symptoms for Aip-Related Familial Isolated Pituitary Adenomas

About this section

Drugs & Therapeutics for Aip-Related Familial Isolated Pituitary Adenomas

About this section
Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Aip-Related Familial Isolated Pituitary Adenomas

Drug clinical trials:

Search ClinicalTrials for Aip-Related Familial Isolated Pituitary Adenomas

Search NIH Clinical Center for Aip-Related Familial Isolated Pituitary Adenomas

Search CenterWatch for Aip-Related Familial Isolated Pituitary Adenomas

Genetic Tests for Aip-Related Familial Isolated Pituitary Adenomas

About this section
Sources:
21GeneTests
See all sources

Genetic tests related to Aip-Related Familial Isolated Pituitary Adenomas:

id Genetic test Affiliating Genes
1 Aip-Related Familial Isolated Pituitary Adenomas21 AIP

Anatomical Context for Aip-Related Familial Isolated Pituitary Adenomas

About this section
Sources:
34MalaCards
See all sources

MalaCards organs/tissues related to Aip-Related Familial Isolated Pituitary Adenomas:

34
Pituitary

Animal Models for Aip-Related Familial Isolated Pituitary Adenomas or affiliated genes

About this section
Sources:
38MGI
See all sources

MGI Mouse Phenotypes related to Aip-Related Familial Isolated Pituitary Adenomas:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053788.5SSTR5, GNAS, AIP
2MP:00053798.2SSTR5, GNAS, AIP

Publications for Aip-Related Familial Isolated Pituitary Adenomas

About this section
Sources:
53PubMed
See all sources

Articles related to Aip-Related Familial Isolated Pituitary Adenomas:

idTitleAuthorsYear
1
AIP-Related Familial Isolated Pituitary Adenomas (22720333)
1993

Variations for Aip-Related Familial Isolated Pituitary Adenomas

About this section
Sources:
1 National Center for Biotechnology Information (Clinvar)
See all sources

Clinvar genetic disease variations for Aip-Related Familial Isolated Pituitary Adenomas:

1
id Gene Name Type Significance SNP ID Assembly Location
1AIPNM_003977.2(AIP): c.804C> A (p.Tyr268Ter)single nucleotide variantLikely pathogenic, Pathogenicrs121908356GRCh37Chr 11, 67258275: 67258275

Expression for genes affiliated with Aip-Related Familial Isolated Pituitary Adenomas

About this section
Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Aip-Related Familial Isolated Pituitary Adenomas

Search GEO for disease gene expression data for Aip-Related Familial Isolated Pituitary Adenomas.

Pathways for genes affiliated with Aip-Related Familial Isolated Pituitary Adenomas

About this section

Compounds for genes affiliated with Aip-Related Familial Isolated Pituitary Adenomas

About this section
Sources:
46Novoseek, 62Tocris Bioscience, 30IUPHAR, 12DrugBank, 25HMDB
See all sources

Compounds related to Aip-Related Familial Isolated Pituitary Adenomas according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1octreotide46 62 30 1212.2SSTR5, GNAS
2acth469.1SSTR5, GNAS
3thymidine46 2510.1SSTR5, GNAS
4ribonucleic acid469.0GNAS, SSTR5
5dopamine46 30 25 1211.8SSTR5, GNAS

GO Terms for genes affiliated with Aip-Related Familial Isolated Pituitary Adenomas

About this section
Sources:
17Gene Ontology
See all sources

Biological processes related to Aip-Related Familial Isolated Pituitary Adenomas according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of insulin secretionGO:0507969.1SSTR5, GNAS

Molecular functions related to Aip-Related Familial Isolated Pituitary Adenomas according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1signal transducer activityGO:0048719.3GNAS, AIP

Products for genes affiliated with Aip-Related Familial Isolated Pituitary Adenomas

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Aip-Related Familial Isolated Pituitary Adenomas

About this section
4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet