MCID: APR002
MIFTS: 23

Aip-Related Familial Isolated Pituitary Adenomas malady

Genetic diseases, Rare diseases, Gastrointestinal diseases categories
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Summaries for Aip-Related Familial Isolated Pituitary Adenomas

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19GeneReviews, 33MalaCards
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MalaCards: Aip-Related Familial Isolated Pituitary Adenomas, also known as pituitary adenoma predisposition, is related to pituitary adenoma and adenoma. An important gene associated with Aip-Related Familial Isolated Pituitary Adenomas is AIP (aryl hydrocarbon receptor interacting protein). The compounds octreotide and acth have been mentioned in the context of this disorder. Affiliated tissues include pituitary, and related mouse phenotypes are growth/size/body and endocrine/exocrine gland.

GeneReviews summary for ipa

Aliases & Classifications for Aip-Related Familial Isolated Pituitary Adenomas

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19GeneReviews, 20GeneTests, 62UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

aip-related familial isolated pituitary adenomas 19 20
pituitary adenoma predisposition 62


Related Diseases for Aip-Related Familial Isolated Pituitary Adenomas

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17GeneCards, 18GeneDecks
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Diseases in the Familial Isolated Pituitary Adenoma family:

aip-related familial isolated pituitary adenomas

Diseases related to Aip-Related Familial Isolated Pituitary Adenomas via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 11)
idRelated DiseaseScoreTop Affiliating Genes
1pituitary adenoma30.6AIP, SSTR5, GNAS
2adenoma30.5AIP, GNAS, SSTR5
3familial isolated pituitary adenoma10.5
4osteomalacia10.1GNAS
5pheochromocytoma10.0GNAS, SSTR5
6gigantism10.0AIP, GNAS
7carney complex10.0GNAS, AIP
8carcinoid syndrome10.0SSTR5, GNAS
9acromegaly9.9SSTR5, GNAS, AIP
10prolactinoma9.9SSTR5, GNAS, AIP
11pituitary tumors9.9SSTR5, AIP, GNAS

Graphical network of diseases related to Aip-Related Familial Isolated Pituitary Adenomas:



Diseases related to aip-related familial isolated pituitary adenomas

Symptoms for Aip-Related Familial Isolated Pituitary Adenomas

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Drugs & Therapeutics for Aip-Related Familial Isolated Pituitary Adenomas

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Aip-Related Familial Isolated Pituitary Adenomas

Search NIH Clinical Center for Aip-Related Familial Isolated Pituitary Adenomas

Genetic Tests for Aip-Related Familial Isolated Pituitary Adenomas

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20GeneTests
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Genetic tests related to Aip-Related Familial Isolated Pituitary Adenomas:

id Genetic test Affiliating Genes
1 Aip-Related Familial Isolated Pituitary Adenomas20 AIP

Anatomical Context for Aip-Related Familial Isolated Pituitary Adenomas

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33MalaCards
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MalaCards organs/tissues related to Aip-Related Familial Isolated Pituitary Adenomas:

33
Pituitary

Animal Models for Aip-Related Familial Isolated Pituitary Adenomas or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Aip-Related Familial Isolated Pituitary Adenomas:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053788.5SSTR5, GNAS, AIP
2MP:00053798.2SSTR5, GNAS, AIP

Publications for Aip-Related Familial Isolated Pituitary Adenomas

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52PubMed
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Articles related to Aip-Related Familial Isolated Pituitary Adenomas:

idTitleAuthorsYear
1
AIP-Related Familial Isolated Pituitary Adenomas (22720333)
1993

Variations for Aip-Related Familial Isolated Pituitary Adenomas

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1 National Center for Biotechnology Information (Clinvar)
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Clinvar genetic disease variations for Aip-Related Familial Isolated Pituitary Adenomas:

1
id Gene Name Type Significance SNP ID Assembly Location
1AIPNM_003977.2(AIP): c.804C> A (p.Tyr268Ter)single nucleotide variantLikely pathogenic, Pathogenicrs121908356GRCh37Chr 11, 67258275: 67258275

Expression for genes affiliated with Aip-Related Familial Isolated Pituitary Adenomas

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Aip-Related Familial Isolated Pituitary Adenomas

Search GEO for disease gene expression data for Aip-Related Familial Isolated Pituitary Adenomas.

Pathways for genes affiliated with Aip-Related Familial Isolated Pituitary Adenomas

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Compounds for genes affiliated with Aip-Related Familial Isolated Pituitary Adenomas

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Sources:
45Novoseek, 61Tocris Bioscience, 29IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Aip-Related Familial Isolated Pituitary Adenomas according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1octreotide45 61 29 1112.2SSTR5, GNAS
2acth459.1SSTR5, GNAS
3thymidine45 2410.1SSTR5, GNAS
4ribonucleic acid459.0GNAS, SSTR5
5dopamine45 29 24 1111.8SSTR5, GNAS

GO Terms for genes affiliated with Aip-Related Familial Isolated Pituitary Adenomas

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16Gene Ontology
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Biological processes related to Aip-Related Familial Isolated Pituitary Adenomas according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of insulin secretionGO:0507969.1SSTR5, GNAS

Molecular functions related to Aip-Related Familial Isolated Pituitary Adenomas according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1signal transducer activityGO:0048719.3GNAS, AIP

Products for genes affiliated with Aip-Related Familial Isolated Pituitary Adenomas

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Aip-Related Familial Isolated Pituitary Adenomas

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet