MCID: ALC013
MIFTS: 28

Alcohol-Induced Mental Disorder

Categories: Mental diseases, Neuronal diseases

Aliases & Classifications for Alcohol-Induced Mental Disorder

MalaCards integrated aliases for Alcohol-Induced Mental Disorder:

Name: Alcohol-Induced Mental Disorder 12 14
Psychoses, Alcoholic 69

Classifications:



External Ids:

Disease Ontology 12 DOID:251
ICD9CM 35 291.8 291.89
UMLS 69 C1456283

Summaries for Alcohol-Induced Mental Disorder

MalaCards based summary : Alcohol-Induced Mental Disorder, also known as psychoses, alcoholic, is related to hyperthyroxinemia and ornithosis. An important gene associated with Alcohol-Induced Mental Disorder is TAPBP (TAP Binding Protein), and among its related pathways/superpathways are Circadian rythm related genes and Monoamine Transport. The drugs Ethanol and Naltrexone have been mentioned in the context of this disorder. Affiliated tissues include liver.

Related Diseases for Alcohol-Induced Mental Disorder

Diseases related to Alcohol-Induced Mental Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 42)
id Related Disease Score Top Affiliating Genes
1 hyperthyroxinemia 10.5 DRD2 SLC6A4
2 ornithosis 10.5 DRD2 SLC6A4
3 pompholyx 10.5 DRD2 SLC6A4
4 anosognosia 10.5 DRD2 SLC6A4
5 anodontia 10.5 SLC6A3 SLC6A4
6 tinea pedis 10.5 SLC6A3 SLC6A4
7 pauci-immune glomerulonephritis with anca 10.4 DRD2 SLC6A4
8 contact dermatitis 10.4 DRD2 SLC6A3
9 pelvic inflammatory disease 10.4 DRD2 SLC6A4
10 eosinophilia-myalgia syndrome 10.4 DRD2 SLC6A3
11 suppurative periapical periodontitis 10.4 DRD2 SLC6A4
12 simpson-golabi-behmel syndrome 10.4 DRD2 SLC6A3
13 tubular variant testicular seminoma 10.3 NPS SLC6A3
14 postencephalitic parkinson disease 10.2 DRD2 SLC6A4
15 asperger syndrome 10.2 DRD2 SLC6A3
16 pyromania 10.2 DRD2 SLC6A3 SLC6A4
17 hemorrhagic cystitis 10.2 DRD2 SLC6A3 SLC6A4
18 tongue disease 10.2 DRD2 SLC6A3 SLC6A4
19 perry syndrome 10.2 NPS SLC6A3
20 bladder hepatoid adenocarcinoma 10.2 DRD2 SLC6A3 SLC6A4
21 hallucinogen dependence 10.2 DRD2 SLC6A4
22 acute female pelvic peritonitis 10.2 DRD2 SLC6A3 SLC6A4
23 alcoholic liver cirrhosis 10.2 DRD2 SLC6A4
24 carotid stenosis 10.2 DRD2 SLC6A3 SLC6A4
25 cecal benign neoplasm 10.2 DRD2 SLC6A3 SLC6A4
26 colon mucinous adenocarcinoma 10.2 DRD2 SLC6A3 SLC6A4
27 perinatal necrotizing enterocolitis 10.1 DRD2 SLC6A3 SLC6A4
28 heroin dependence 10.1 DRD2 SLC6A3 SLC6A4
29 hepatitis d 10.1 DRD2 SLC6A3 SLC6A4
30 chronic conjunctivitis 10.1 DRD2 SLC6A3 SLC6A4
31 aicardi-goutieres syndrome 2 10.1 DRD2 SLC6A3 SLC6A4
32 bone fracture 10.1 DRD2 SLC6A3 SLC6A4
33 albinism, oculocutaneous, type v 10.1 DRD2 NPS SLC6A4
34 hereditary multiple exostoses 10.1 DRD2 SLC6A4
35 epileptic encephalopathy, early infantile, 45 10.0 DRD2 SLC6A3 SLC6A4
36 sexual disorder 10.0 DRD2 SLC6A3 SLC6A4
37 craniosynostosis, adelaide type 10.0 DRD2 SLC6A3 SLC6A4
38 parkinson disease, late-onset 9.9 DRD2 SLC6A3 SLC6A4
39 bladder flat intraepithelial lesion 9.9 DRD2 SLC6A4
40 personality disorder 9.7 DRD2 NPS SLC6A3 SLC6A4
41 intracranial cavernous angioma 6.6 CDK9 DRD2 ERLEC1 ITFG1 MEPE NPS
42 splenic abscess 6.6 CDK9 DRD2 ERLEC1 ITFG1 MEPE NPS

Comorbidity relations with Alcohol-Induced Mental Disorder via Phenotypic Disease Network (PDN):


Alcohol Abuse

Graphical network of the top 20 diseases related to Alcohol-Induced Mental Disorder:



Diseases related to Alcohol-Induced Mental Disorder

Symptoms & Phenotypes for Alcohol-Induced Mental Disorder

Drugs & Therapeutics for Alcohol-Induced Mental Disorder

Drugs for Alcohol-Induced Mental Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 78)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1 64-17-5 702
2
Naltrexone Approved, Investigational, Vet_approved Phase 4 16590-41-3 5360515
3
Dopamine Approved Phase 4,Phase 2 51-61-6, 62-31-7 681
4
Lorazepam Approved Phase 4 846-49-1 3958
5
Ziprasidone Approved Phase 4 146939-27-7 60854
6
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
7
Thiamine Approved, Nutraceutical, Vet_approved Phase 4 59-43-8 1130
8
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
9
Betadex Experimental Phase 4 7585-39-9 320761
10 Vitamins Phase 4
11 Central Nervous System Depressants Phase 4,Phase 2,Phase 1
12 Neurotransmitter Agents Phase 4,Phase 2,Phase 1
13 Anti-Infective Agents Phase 4,Phase 2,Phase 1
14 Anti-Infective Agents, Local Phase 4,Phase 2,Phase 1
15 Narcotic Antagonists Phase 4
16 Narcotics Phase 4
17 Peripheral Nervous System Agents Phase 4,Phase 2
18 Dopamine Agents Phase 4,Phase 2
19 Psychotropic Drugs Phase 4
20 Tranquilizing Agents Phase 4
21 Anti-Anxiety Agents Phase 4
22 Anticonvulsants Phase 4,Phase 2
23 Antiemetics Phase 4
24 Autonomic Agents Phase 4
25 GABA Agents Phase 4
26 GABA Modulators Phase 4
27 Gastrointestinal Agents Phase 4,Phase 2,Phase 1
28 Hypnotics and Sedatives Phase 4
29 Micronutrients Phase 4
30 Trace Elements Phase 4
31 Vitamin B Complex Phase 4
32 Antipsychotic Agents Phase 4
33 Dopamine Antagonists Phase 4
34 Pharmaceutical Solutions Phase 4
35
Serotonin Phase 4 50-67-9 5202
36 Serotonin Agents Phase 4
37 Serotonin Antagonists Phase 4
38 Adrenergic Agents Phase 4
39 Adrenergic Agonists Phase 4
40 Adrenergic alpha-2 Receptor Agonists Phase 4
41 Adrenergic alpha-Agonists Phase 4
42 Analgesics Phase 4
43 Analgesics, Non-Narcotic Phase 4
44 Thiamin Nutraceutical Phase 4
45 Folate Nutraceutical Phase 4
46 Vitamin B9 Nutraceutical Phase 4
47
Baclofen Approved Phase 3 1134-47-0 2284
48
Progesterone Approved, Vet_approved Phase 2, Phase 3 57-83-0 5994
49 Liver Extracts Phase 3,Phase 2
50 Hormone Antagonists Phase 2, Phase 3

Interventional clinical trials:

(show all 32)

id Name Status NCT ID Phase Drugs
1 Naltrexone for Heavy Drinking in Young Adults Completed NCT00568958 Phase 4 naltrexone;placebo naltrexone
2 Optimum Thiamine Intervention (OpTIn) Trial Recruiting NCT02788552 Phase 4 Thiamine Hydrochloride
3 The Efficacy And Safety Of Intramuscular Ziprasidone For Three Days In Patients With Psychotic Agitation Not yet recruiting NCT02935998 Phase 4 Ziprasidone
4 Dexmedetomidine (Precedex®) for Severe Alcohol Withdrawal Syndrome (AWS) and Alcohol Withdrawal Delirium (AWD) Terminated NCT01362205 Phase 4 Dexmedetomidine;Placebos
5 Baclofen in the Treatment of Alcohol Dependence With or Without Alcoholic Liver Disease Completed NCT01711125 Phase 3 Baclofen 30mg/day;Baclofen 75mg/day;Placebo
6 Progesterone Effect on Individuals Diagnoses With AD and PTSD. Recruiting NCT02187224 Phase 2, Phase 3 Progesterone;Placebo (for Progesterone)
7 New Medications to Treat Alcohol Dependence Completed NCT00223639 Phase 2 Topiramate
8 Modafinil, DRD4 Genotype and Cocaine Relapse Completed NCT01778010 Phase 2 Modafinil;Cocaine
9 Choline Supplementation in Children With Fetal Alcohol Spectrum Disorders Completed NCT01911299 Phase 2
10 A Novel Pharmacotherapy for Alcoholism and Alcohol Liver Disease Completed NCT01504295 Phase 2 Metadoxine
11 Neurocognitive Habilitation for Children With Fetal Alcohol Syndrome (FAS)/Alcohol-Related Neurodevelopmental Disorder (ARND) Completed NCT00164346 Phase 1, Phase 2
12 Postnatal Choline Supplementation in Children With Prenatal Alcohol Exposure Completed NCT01149538 Phase 1, Phase 2 Choline bitartrate
13 Carisbamate as a Potential Treatment for Alcohol Dependence Active, not recruiting NCT02435381 Phase 1, Phase 2 Carisbamate;Placebo
14 Topiramate to Reduce Heavy Drinking in HIV-Positive Heavy Drinkers Terminated NCT01764685 Phase 2 Topiramate;Placebo
15 A Trial Evaluating Pitolisant (BF2.649) in Alcohol Use Disorder Treatment Withdrawn NCT02800083 Phase 2 Pitolisant (BF2.649);Placebo
16 Neurosteroids and Acute Alcohol Intoxication in Humans Unknown status NCT00608686 Phase 1
17 Fish Oil vs. Placebo on Subjective Effects of Alcohol Not yet recruiting NCT03010917 Phase 1 Fish Oil with ethanol and placebo ethanol infusions;Placebo with ethanol and placebo ethanol infusions
18 Health Mobile Cognitive Stimulation in Alcoholics Unknown status NCT01942954
19 From Uncomplicated Alcoholism to Korsakoff's Syndrome Unknown status NCT01455207
20 Cutaneous Denervation in Alcoholic Neuropathy Unknown status NCT00190073
21 Neural Mechanisms Underlying Alcohol Induced Disinhibition Completed NCT01097213 Ethanol;Placebo - half-normal saline
22 Somatic Disease Among Alcohol Abusers in an Out-day Patients' Clinic Completed NCT01081197
23 Fetal Alcohol Damage Prevention Study Completed NCT00696085
24 Treating Alcohol Withdrawal With Oral Baclofen Completed NCT00597701 Baclofen;Placebo;Lorazepam
25 Improving Self Regulation in Children With Fetal Alcohol Syndrome Spectrum Disorders: A Neuroplastic Intervention Completed NCT02457676
26 Development of Education Materials for Prevention of FAS in Russia Completed NCT01971398
27 Expansion to Interdisciplinary HIV Prevention in Women Completed NCT01994603
28 Preventing FAS/ARND in Russian Children Completed NCT01961050
29 Parenting Training for Children With FASD Recruiting NCT02210455
30 SBIRT Implementation for Adolescents in Urban Federally Qualified Health Centers Active, not recruiting NCT01829308
31 Transient Elastography in the Determination of Advanced Fibrosis in Alcoholic Liver Disease. Active, not recruiting NCT01789008
32 Prevention of Fetal Alcohol Spectrum Disorder (FASD) by the Use of Technology Enrolling by invitation NCT02759874

Search NIH Clinical Center for Alcohol-Induced Mental Disorder

Genetic Tests for Alcohol-Induced Mental Disorder

Anatomical Context for Alcohol-Induced Mental Disorder

MalaCards organs/tissues related to Alcohol-Induced Mental Disorder:

39
Liver

Publications for Alcohol-Induced Mental Disorder

Articles related to Alcohol-Induced Mental Disorder:

id Title Authors Year
1
A Comparison Study of Quetiapine and Risperidone's Effectiveness and Safety on Treating Alcohol-induced Mental Disorder. ( 28638193 )
2016
2
Microsurgical tissue transfers for head and neck reconstruction in patients with alcohol-induced mental disorder. ( 17973172 )
2008

Variations for Alcohol-Induced Mental Disorder

Expression for Alcohol-Induced Mental Disorder

Search GEO for disease gene expression data for Alcohol-Induced Mental Disorder.

Pathways for Alcohol-Induced Mental Disorder

GO Terms for Alcohol-Induced Mental Disorder

Biological processes related to Alcohol-Induced Mental Disorder according to GeneCards Suite gene sharing:

(show all 13)
id Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 9.56 CDK9 DRD2 SLC6A3 SLC6A4
2 visual learning GO:0008542 9.52 DRD2 NPS
3 neurotransmitter transport GO:0006836 9.51 SLC6A3 SLC6A4
4 response to nicotine GO:0035094 9.49 DRD2 SLC6A3
5 response to cocaine GO:0042220 9.48 DRD2 SLC6A3
6 positive regulation of multicellular organism growth GO:0040018 9.46 DRD2 SLC6A3
7 response to iron ion GO:0010039 9.43 DRD2 SLC6A3
8 neurotransmitter biosynthetic process GO:0042136 9.4 SLC6A3 SLC6A4
9 ammonium transmembrane transport GO:0072488 9.37 SLC6A3 SLC6A4
10 prepulse inhibition GO:0060134 9.32 DRD2 SLC6A3
11 adenohypophysis development GO:0021984 9.16 DRD2 SLC6A3
12 monoamine transport GO:0015844 8.96 SLC6A3 SLC6A4
13 dopamine uptake involved in synaptic transmission GO:0051583 8.62 SLC6A3 SLC6A4

Molecular functions related to Alcohol-Induced Mental Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 neurotransmitter:sodium symporter activity GO:0005328 9.26 SLC6A3 SLC6A4
2 dopamine binding GO:0035240 9.16 DRD2 SLC6A3
3 monoamine transmembrane transporter activity GO:0008504 8.96 SLC6A3 SLC6A4
4 dopamine:sodium symporter activity GO:0005330 8.62 SLC6A3 SLC6A4

Sources for Alcohol-Induced Mental Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....