MCID: ALC002
MIFTS: 22

Alcohol-Related Neurodevelopmental Disorder

Categories: Neuronal diseases, Mental diseases

Aliases & Classifications for Alcohol-Related Neurodevelopmental Disorder

MalaCards integrated aliases for Alcohol-Related Neurodevelopmental Disorder:

Name: Alcohol-Related Neurodevelopmental Disorder 12 14
Static Encephalopathy 12 69
Alcohol Related Neurodevelopmental Disorder 69
Arnd 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0050667

Summaries for Alcohol-Related Neurodevelopmental Disorder

Disease Ontology : 12 A fetal alcohol spectrum disorder that results in central nervous system dysfunction and behavioral and/or cognitive deficits due to prenatal alcohol exposure.

MalaCards based summary : Alcohol-Related Neurodevelopmental Disorder, also known as static encephalopathy, is related to fetal alcohol syndrome and neurodegeneration with brain iron accumulation 5. An important gene associated with Alcohol-Related Neurodevelopmental Disorder is PFAS (Phosphoribosylformylglycinamidine Synthase). The drugs Ethanol and Choline have been mentioned in the context of this disorder.

Related Diseases for Alcohol-Related Neurodevelopmental Disorder

Diseases related to Alcohol-Related Neurodevelopmental Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 fetal alcohol syndrome 12.1
2 neurodegeneration with brain iron accumulation 5 12.0
3 fetal alcohol spectrum disorder 11.8
4 encephalopathy 10.1
5 substance abuse 9.9
6 conjunctivitis 9.9
7 developmental dysplasia of the hip 1 9.7
8 cerebral creatine deficiency syndrome 1 9.7
9 cerebral palsy 9.7
10 cerebritis 9.7
11 glycine encephalopathy 8.9 BOLA3 GCSH GLRX5

Graphical network of the top 20 diseases related to Alcohol-Related Neurodevelopmental Disorder:



Diseases related to Alcohol-Related Neurodevelopmental Disorder

Symptoms & Phenotypes for Alcohol-Related Neurodevelopmental Disorder

Drugs & Therapeutics for Alcohol-Related Neurodevelopmental Disorder

Drugs for Alcohol-Related Neurodevelopmental Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethanol Approved Phase 1, Phase 2 64-17-5 702
2
Choline Approved, Nutraceutical Phase 2,Phase 1 62-49-7 305
3 Anti-Infective Agents Phase 1, Phase 2
4 Anti-Infective Agents, Local Phase 1, Phase 2
5 Central Nervous System Depressants Phase 1, Phase 2
6 Antimetabolites Phase 2,Phase 1
7 Gastrointestinal Agents Phase 2,Phase 1
8 Hypolipidemic Agents Phase 2,Phase 1
9 Lipid Regulating Agents Phase 2,Phase 1
10 Nootropic Agents Phase 2,Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Neurocognitive Habilitation for Children With Fetal Alcohol Syndrome (FAS)/Alcohol-Related Neurodevelopmental Disorder (ARND) Completed NCT00164346 Phase 1, Phase 2
2 Choline Supplementation in Children With Fetal Alcohol Spectrum Disorders Completed NCT01911299 Phase 2
3 Postnatal Choline Supplementation in Children With Prenatal Alcohol Exposure Completed NCT01149538 Phase 1, Phase 2 Choline bitartrate
4 Parenting Training for Children With FASD Unknown status NCT02210455
5 Development of Education Materials for Prevention of FAS in Russia Completed NCT01971398
6 Expansion to Interdisciplinary HIV Prevention in Women Completed NCT01994603
7 Preventing FAS/ARND in Russian Children Completed NCT01961050

Search NIH Clinical Center for Alcohol-Related Neurodevelopmental Disorder

Genetic Tests for Alcohol-Related Neurodevelopmental Disorder

Anatomical Context for Alcohol-Related Neurodevelopmental Disorder

Publications for Alcohol-Related Neurodevelopmental Disorder

Articles related to Alcohol-Related Neurodevelopmental Disorder:

# Title Authors Year
1
Visual search for feature conjunctions: an fMRI study comparing alcohol-related neurodevelopmental disorder (ARND) to ADHD. ( 25750685 )
2015
2
Hippocampal abnormalities in youth with alcohol-related neurodevelopmental disorder. ( 24512673 )
2014
3
Cortical morphology in children with alcohol-related neurodevelopmental disorder. ( 24653953 )
2014
4
The Toronto experience in diagnosing alcohol-related neurodevelopmental disorder: a unique profile of deficits and assets. ( 12584580 )
2002
5
American Academy of Pediatrics. Committee on Substance Abuse and Committee on Children With Disabilities. Fetal alcohol syndrome and alcohol-related neurodevelopmental disorders. ( 10920168 )
2000
6
Incidence of fetal alcohol syndrome and prevalence of alcohol-related neurodevelopmental disorder. ( 9451756 )
1997
7
What research with animals is telling us about alcohol-related neurodevelopmental disorder. ( 8981579 )
1996

Variations for Alcohol-Related Neurodevelopmental Disorder

Expression for Alcohol-Related Neurodevelopmental Disorder

Search GEO for disease gene expression data for Alcohol-Related Neurodevelopmental Disorder.

Pathways for Alcohol-Related Neurodevelopmental Disorder

GO Terms for Alcohol-Related Neurodevelopmental Disorder

Biological processes related to Alcohol-Related Neurodevelopmental Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein lipoylation GO:0009249 8.62 GCSH GLRX5

Sources for Alcohol-Related Neurodevelopmental Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....