MCID: ALC006
MIFTS: 57

Alcoholic Hepatitis malady

Gastrointestinal diseases, Liver diseases categories

Summaries for Alcoholic Hepatitis

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Wikipedia:64 Alcoholic hepatitis is hepatitis (inflammation of the liver) due to excessive intake of alcohol. It is... more...

MalaCards based summary: Alcoholic Hepatitis, also known as acute alcoholic liver disease, is related to hepatitis and hepatorenal syndrome. An important gene associated with Alcoholic Hepatitis is F2 (coagulation factor II (thrombin)), and among its related pathways are Calcineurin-regulated NFAT-dependent transcription in lymphocytes and Legionellosis. The compounds n-tosyl-l-phenylalanine chloromethyl ketone and azithromycin have been mentioned in the context of this disorder. Affiliated tissues include liver, brain and neutrophil, and related mouse phenotypes are no phenotypic analysis and liver/biliary system.

Aliases & Classifications for Alcoholic Hepatitis

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Alcoholic Hepatitis, Aliases & Descriptions:

Name: Alcoholic Hepatitis 31 9
Acute Alcoholic Liver Disease 9 61
Acute Alcoholic Hepatitis 9 44
 
Hepatitis, Alcoholic 61
Hepatitis Alcoholic 44


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases, Liver diseases


External Ids:

Disease Ontology9 DOID:12351
NCIt39 C34352
SNOMED-CT56 155810001, 9953008
ICD9CM28 571.1
ICD1026 K70.1

Related Diseases for Alcoholic Hepatitis

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Diseases related to Alcoholic Hepatitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 110)
idRelated DiseaseScoreTop Affiliating Genes
1hepatitis32.3CYP2E1, F2, HGF
2hepatorenal syndrome31.3F2
3hepatitis c30.7CYP2E1, IL10, F2
4hepatitis b30.6F2, IL10
5liver cirrhosis30.5CYP2E1, F2, HGF
6alcoholic liver cirrhosis30.5CYP2E1, F2, IL8
7acute liver failure30.4F2, HGF
8peritonitis30.2F2, TNF
9acute pancreatitis29.9IL10, IL8
10pancreatitis29.8CYP2E1, ICAM1, IL10
11pneumonia29.3IL22, IL10, TNF, IL8, ICAM1
12hepatitis a10.7
13liver disease10.5
14blau syndrome10.4TNF
15hepatitis c virus10.4
16blindness10.4
17interstitial lung disease10.4TNF
18meningitis10.4IL8
19leukostasis10.4ICAM1
20rheumatoid vasculitis10.4ICAM1
21leukemoid reaction10.3
22nonalcoholic steatohepatitis10.3
23leishmaniasis10.3IL10
24chorioamnionitis10.2TNF, IL8
25arthritis10.2IL8, TNF
26hepatic encephalopathy10.2
27galactosemia10.2HGF, F2
28adult respiratory distress syndrome10.2TNF, IL8
29common cold10.2ICAM1, IL8
30allergic rhinitis10.2ICAM1, IL8
31cork-handlers' disease10.2IL8, F2
32behcet's disease10.2IL8, TNF
33vernal keratoconjunctivitis10.2IL8, ICAM1
34arteriosclerosis obliterans10.2ICAM1, HGF
35arteriosclerosis10.1ICAM1, HGF
36rhinitis10.1ICAM1, IL8
37hypertension10.1
38thrombocytopenia10.1
39portal hypertension10.1
40esophagitis10.1
41hepatoblastoma10.1CYP2E1, HGF
42pulmonary sarcoidosis10.1ICAM1, TNF
43respiratory failure10.1ICAM1, TNF
44monocytic leukemia10.1TNF, IL8
45chronic obstructive pulmonary disease10.1IL8, TNF, CYP2E1
46periodontal disease10.1TNF, IL8
47acute graft versus host disease10.1IL10, TNF
48demyelinating disease10.0IL10, TNF
49proliferative diabetic retinopathy10.0ICAM1, HGF, IL8
50vasculitis10.0ICAM1, TNF, F2

Graphical network of the top 20 diseases related to Alcoholic Hepatitis:



Diseases related to alcoholic hepatitis

Symptoms for Alcoholic Hepatitis

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Drugs & Therapeutics for Alcoholic Hepatitis

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Drug clinical trials:

Search ClinicalTrials for Alcoholic Hepatitis

Search NIH Clinical Center for Alcoholic Hepatitis

Genetic Tests for Alcoholic Hepatitis

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Anatomical Context for Alcoholic Hepatitis

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MalaCards organs/tissues related to Alcoholic Hepatitis:

32
Liver, Brain, Neutrophil, T cells, Monocytes, Testes, Bone, Whole blood, Kidney, Thyroid, Prostate, Endothelial

Animal Models for Alcoholic Hepatitis or affiliated genes

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MGI Mouse Phenotypes related to Alcoholic Hepatitis:

36 (show all 13)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030128.1IL22, IL10, HGF, TNF
2MP:00053708.0HGF, IL10, IL22, TNF, CYP2E1
3MP:00053888.0IL10, F2, TNF, IL22
4MP:00020067.9IL10, ICAM1, IL22, CYP2E1, TNF
5MP:00053817.8F2, TNF, ICAM1, IL22, IL10
6MP:00107717.8TNF, ICAM1, IL22, IL10, F2
7MP:00053847.7IL10, HGF, ICAM1, TNF, F2
8MP:00053857.6F2, CYP2E1, TNF, ICAM1, IL10, HGF
9MP:00053877.4F2, TNF, IL22, IL10, IL8, ICAM1
10MP:00053767.3CYP2E1, ICAM1, IL22, F2, TNF, IL10
11MP:00053787.3HGF, IL10, IL22, ICAM1, TNF, F2
12MP:00053977.0F2, HGF, IL8, IL10, IL22, ICAM1
13MP:00107687.0HGF, IL22, ICAM1, TNF, CYP2E1, F2

Publications for Alcoholic Hepatitis

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Articles related to Alcoholic Hepatitis:

(show top 50)    (show all 521)
idTitleAuthorsYear
1
TLR3/4 signaling is mediated via the NFI_B-CXCR4/7 pathway in human alcoholic hepatitis and non-alcoholic steatohepatitis which formed Mallory-Denk bodies. (24997224)
2014
2
Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis. (22278680)
2012
3
Molecular targets in the treatment of alcoholic hepatitis. (23112542)
2012
4
Severe acute alcoholic hepatitis and hepatorenal syndrome: role of transjugular intrahepatic portosystemic stent shunt. (22802893)
2012
5
Severe alcoholic hepatitis: glucocorticoid saves lives and transplantation is promising. (21633648)
2011
6
Definition, epidemiology and magnitude of alcoholic hepatitis. (21731902)
2011
7
Development of multiple peribiliary cysts following acute alcoholic hepatitis. (20658328)
2010
8
The place of liver transplantation in the treatment of severe alcoholic hepatitis. (20347501)
2010
9
Alcoholic hepatitis 2010: a clinician's guide to diagnosis and therapy. (20954276)
2010
10
Acetate, the key modulator of inflammatory responses in acute alcoholic hepatitis. (20232292)
2010
11
Glucocorticoids can help in acute severe alcoholic hepatitis. (19566906)
2009
12
Alcoholic hepatitis. (19812414)
2009
13
Antioxidants plus corticosteroids in the treatment of severe acute alcoholic hepatitis: the question is still open. (18486264)
2008
14
Alcoholic hepatitis with leukemoid reaction after surgery. (16368495)
2006
15
Future use of the Glasgow alcoholic hepatitis score. (16344584)
2006
16
Regulation of fat metabolism in the liver: link to non-alcoholic hepatic steatosis and impact of physical exercise. (16649140)
2006
17
Current concepts and controversies in the treatment of alcoholic hepatitis. (17109510)
2006
18
Serum C-reactive protein: a non-invasive marker of alcoholic hepatitis. (17101579)
2006
19
Duplex Doppler ultrasound of the hepatic artery in patients with acute alcoholic hepatitis. (11960073)
2002
20
Role of Kupffer cells in alcoholic hepatitis. (12062631)
2002
21
Is pentoxifylline the answer for alcoholic hepatitis? (12170912)
2002
22
Influence of superimposed alcoholic hepatitis on the outcome of liver transplantation for end-stage alcoholic liver disease. (12044530)
2002
23
Free radicals, chemokines, and cell injury in HIV-1 and SIV infections and alcoholic hepatitis. (11744325)
2001
24
Serum laminin and type IV collagen are accurate markers of histologically severe alcoholic hepatitis in patients with cirrhosis. (10735610)
2000
25
Antioxidants attenuate nuclear factor-kappa B activation and tumor necrosis factor-alpha production in alcoholic hepatitis patient monocytes and rat Kupffer cells, in vitro. (10614719)
1999
26
Nonalcoholic steatohepatitis. Clinicopathological comparison with alcoholic hepatitis in ambulatory and hospitalized patients. (8565753)
1996
27
Prognostic factors for short-term survival in alcoholic hepatitis in Japan: analysis by logistic regression. (8986243)
1996
28
Protein energy malnutrition in severe alcoholic hepatitis: diagnosis and response to treatment. The VA Cooperative Study Group #275. (8523623)
1995
29
Lack of plasma complement activation in severe acute alcoholic hepatitis. (8749823)
1995
30
Thrombocytopenia associated with platelet-associated immunoglobulin G in alcoholic hepatitis. (7827308)
1994
31
Liver transplantation for alcoholic liver disease: survival of patients transplanted with alcoholic hepatitis plus cirrhosis as compared with those with cirrhosis alone. (8279673)
1993
32
Immunoglobulin A antibody to a 200-kilodalton cytosolic acetaldehyde adduct in alcoholic hepatitis. (1451979)
1992
33
Corticosteroids and alcoholic hepatitis. (1824838)
1991
34
A randomized, controlled trial of treatment of alcoholic hepatitis with parenteral nutrition and oxandrolone. II. Short-term effects on nitrogen metabolism, metabolic balance, and nutrition. (1909086)
1991
35
Do corticosteroids reduce mortality from alcoholic hepatitis? A meta-analysis of the randomized trials. (2142869)
1990
36
Increased plasma tumor necrosis factor in severe alcoholic hepatitis. (2339855)
1990
37
Alcoholic hepatitis: pathogenesis and approaches to treatment. (2237274)
1990
38
Corticosteroid therapy of alcoholic hepatitis: how many studies will it take? (2205560)
1990
39
Tumor necrosis factor in alcoholic hepatitis. (2777030)
1989
40
Metabolic effects of enteral formula feeding in alcoholic hepatitis. (3119452)
1987
41
Plasma lipoprotein composition in alcoholic hepatitis: accumulation of apolipoprotein E-rich high density lipoprotein and preferential reappearance of "light'-HDL during partial recovery. (7097121)
1982
42
Double-blind, controlled trial of propylthiouracil in patients with severe acute alcoholic hepatitis. (7037524)
1982
43
Acute alcoholic hepatitis: clinical, biochemical and liver scintiscanning correlation in assessing prognosis. (472544)
1979
44
Hyperalimentation in alcoholic hepatitis. (119434)
1979
45
The role of lecithin:cholesterol acyltransferase deficiency in the apoprotein metabolism of alcoholic hepatitis. (746350)
1978
46
Immunological aspects of alcoholic hepatitis. (95720)
1978
47
Alcoholic hepatitis. (644352)
1978
48
Lymphocyte cytotoxicity in alcoholic hepatitis. (65306)
1977
49
Editorial: Alcoholic hepatitis and corticosteroids. (4751745)
1973
50
Prednisone therapy of acute alcoholic hepatitis. Report of a controlled trial. (4751740)
1973

Variations for Alcoholic Hepatitis

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Expression for genes affiliated with Alcoholic Hepatitis

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets, 31LifeMap Discovery®
See all sources
LifeMap Discovery
Genes differentially expressed in tissues of Alcoholic Hepatitis patients vs. healthy controls: 31 (show all 400)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1AKR1B10aldo-keto reductase family 1, member B10 (aldose reductase)Liver+8.790.000
2KRT23keratin 23 (histone deacetylase inducible)Liver+7.040.000
3FOSFBJ murine osteosarcoma viral oncogene homologLiver-6.750.000
4CCL20chemokine (C-C motif) ligand 20Liver+6.560.000
5KCNN2potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2Liver-6.110.000
6SPINK1serine peptidase inhibitor, Kazal type 1Liver+6.070.000
7SPP1secreted phosphoprotein 1Liver+6.040.000
8LCN2lipocalin 2Liver+5.740.000
9CXCL6chemokine (C-X-C motif) ligand 6Liver+5.550.000
10COL1A2collagen, type I, alpha 2Liver+5.330.000
11FOSBFBJ murine osteosarcoma viral oncogene homolog BLiver-5.080.000
12LOXL4lysyl oxidase-like 4Liver+5.010.000
13PDZK1IP1PDZK1 interacting protein 1Liver+4.950.000
14CYP1A2cytochrome P450, family 1, subfamily A, polypeptide 2Liver-4.910.000
15GOLM1golgi membrane protein 1Liver+4.870.000
16NR4A2nuclear receptor subfamily 4, group A, member 2Liver-4.850.000
17MMP7matrix metallopeptidase 7 (matrilysin, uterine)Liver+4.730.000
18EFEMP1EGF containing fibulin-like extracellular matrix protein 1Liver+4.630.000
19CD24CD24 moleculeLiver+4.570.000
20GNMTglycine N-methyltransferaseLiver-4.500.000
21PCOLCE2procollagen C-endopeptidase enhancer 2Liver-4.480.000
22CYP2C19cytochrome P450, family 2, subfamily C, polypeptide 19Liver-4.450.000
23TACSTD2tumor-associated calcium signal transducer 2Liver+4.410.000
24DCDC2doublecortin domain containing 2Liver+4.280.000
25EPCAMepithelial cell adhesion moleculeLiver+4.260.000
26NQO1NAD(P)H dehydrogenase, quinone 1Liver+4.100.000
27MT1Mmetallothionein 1MLiver-4.070.000
28SOX9SRY (sex determining region Y)-box 9Liver+3.990.000
29THBS2thrombospondin 2Liver+3.980.000
30KRT7keratin 7Liver+3.960.000
31BICC1BicC family RNA binding protein 1Liver+3.960.000
32FABP4fatty acid binding protein 4, adipocyteLiver+3.940.000
33IL32interleukin 32Liver+3.940.000
34PPP1R1Aprotein phosphatase 1, regulatory (inhibitor) subunit 1ALiver-3.910.000
35RRM2ribonucleotide reductase M2Liver+3.900.000
36IL8interleukin 8Liver+3.900.000
37VCANversicanLiver+3.900.000
38COL1A1collagen, type I, alpha 1Liver+3.890.000
39DUSP1dual specificity phosphatase 1Liver-3.890.000
40LGSNlengsin, lens protein with glutamine synthetase domainLiver-3.780.000
41COL5A1collagen, type V, alpha 1Liver+3.770.000
42SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1Liver-3.770.000
43RGS4regulator of G-protein signaling 4Liver+3.760.000
44STMN2stathmin 2Liver+3.720.000
45SOX4SRY (sex determining region Y)-box 4Liver+3.710.000
46CLEC4MC-type lectin domain family 4, member MLiver-3.690.000
47ANXA2annexin A2Liver+3.670.000
48ANXA2P2annexin A2 pseudogene 2Liver+3.660.000
49CNDP1carnosine dipeptidase 1 (metallopeptidase M20 family)Liver-3.650.000
50GPR88G protein-coupled receptor 88Liver-3.640.000
51DTNAdystrobrevin, alphaLiver+3.620.000
52GADD45Ggrowth arrest and DNA-damage-inducible, gammaLiver-3.590.000
53FAT1FAT atypical cadherin 1Liver+3.590.000
54C15orf48chromosome 15 open reading frame 48Liver+3.560.000
55BBOX1butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1Liver-3.560.000
56CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)Liver+3.510.000
57ACSL4acyl-CoA synthetase long-chain family member 4Liver+3.510.000
58CTHRC1collagen triple helix repeat containing 1Liver+3.500.000
59SLC51Bsolute carrier family 51, beta subunitLiver+3.490.001
60CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)Liver+3.480.000
61OATornithine aminotransferaseLiver-3.470.000
62KDELR3KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3Liver+3.470.000
63EPB41L4Berythrocyte membrane protein band 4.1 like 4BLiver-3.470.000
64LXNlatexinLiver+3.450.000
65PZPpregnancy-zone proteinLiver-3.450.000
66NAMPTnicotinamide phosphoribosyltransferaseLiver-3.450.000
67CD109CD109 moleculeLiver+3.400.000
68S100PS100 calcium binding protein PLiver+3.380.014
69COL4A1collagen, type IV, alpha 1Liver+3.370.000
70IDO2indoleamine 2,3-dioxygenase 2Liver-3.360.000
71MMEmembrane metallo-endopeptidaseLiver-3.340.000
72SDSserine dehydrataseLiver-3.330.016
73AKR1D1aldo-keto reductase family 1, member D1Liver-3.290.000
74LGALS3lectin, galactoside-binding, soluble, 3Liver+3.290.000
75GPX2glutathione peroxidase 2 (gastrointestinal)Liver+3.290.000
76HAO2hydroxyacid oxidase 2 (long chain)Liver-3.280.000
77AQP1aquaporin 1 (Colton blood group)Liver+3.270.000
78CA12carbonic anhydrase XIILiver+3.250.000
79RGS1regulator of G-protein signaling 1Liver-3.240.000
80SORL1sortilin-related receptor, L(DLR class) A repeats containingLiver-3.240.000
81SRD5A2steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)Liver-3.220.000
82LPAlipoprotein, Lp(a)Liver-3.220.001
83ANXA13annexin A13Liver+3.210.000
84CD5LCD5 molecule-likeLiver-3.200.001
85RPS27ribosomal protein S27Liver-3.190.000
86TNFRSF12Atumor necrosis factor receptor superfamily, member 12ALiver+3.190.000
87B4GALT1UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1Liver-3.180.000
88KLHL29kelch-like family member 29Liver+3.170.000
89SIK1salt-inducible kinase 1Liver-3.160.000
90SSTR1somatostatin receptor 1Liver-3.150.000
91TIMP1TIMP metallopeptidase inhibitor 1Liver+3.150.000
92EGR1early growth response 1Liver-3.120.000
93CSRNP1cysteine-serine-rich nuclear protein 1Liver-3.120.000
94CYP1A1cytochrome P450, family 1, subfamily A, polypeptide 1Liver-3.120.000
95TRNP1TMF1-regulated nuclear protein 1Liver+3.120.000
96GADD45Bgrowth arrest and DNA-damage-inducible, betaLiver-3.110.000
97LGALS4lectin, galactoside-binding, soluble, 4Liver+3.110.000
98CDH11cadherin 11, type 2, OB-cadherin (osteoblast)Liver+3.110.000
99CHI3L1chitinase 3-like 1 (cartilage glycoprotein-39)Liver+3.090.010
100IL1RAPinterleukin 1 receptor accessory proteinLiver-3.090.000
101PDK4pyruvate dehydrogenase kinase, isozyme 4Liver-3.060.000
102COL3A1collagen, type III, alpha 1Liver+3.040.000
103CFHR3complement factor H-related 3Liver-3.040.000
104FSTfollistatinLiver-3.040.000
105EEF1A2eukaryotic translation elongation factor 1 alpha 2Liver+3.030.001
106PLP2proteolipid protein 2 (colonic epithelium-enriched)Liver+3.030.000
107SLCO1B3solute carrier organic anion transporter family, member 1B3Liver-3.020.002
108TAX1BP3Tax1 (human T-cell leukemia virus type I) binding protein 3Liver+3.020.000
109SLC44A3solute carrier family 44, member 3Liver+3.010.000
110SLC16A10solute carrier family 16 (aromatic amino acid transporter), member 10Liver-3.010.000
111PHLDA2pleckstrin homology-like domain, family A, member 2Liver+3.010.000
112LOXL2lysyl oxidase-like 2Liver+2.970.000
113CPS1-IT1CPS1 intronic transcript 1 (non-protein coding)Liver-2.970.001
114ATF3activating transcription factor 3Liver-2.960.000
115PTTG1pituitary tumor-transforming 1Liver+2.960.001
116HGFhepatocyte growth factor (hepapoietin A; scatter factor)Liver+2.960.000
117EFHD1EF-hand domain family, member D1Liver-2.960.000
118CYP7A1cytochrome P450, family 7, subfamily A, polypeptide 1Liver-2.950.045
119ZG16zymogen granule protein 16Liver-2.950.000
120F2RL1coagulation factor II (thrombin) receptor-like 1Liver+2.940.000
121TMEM45Btransmembrane protein 45BLiver+2.940.001
122DEFB1defensin, beta 1Liver+2.940.000
123COL4A2collagen, type IV, alpha 2Liver+2.940.000
124NR4A1nuclear receptor subfamily 4, group A, member 1Liver-2.930.000
125CCDC80coiled-coil domain containing 80Liver+2.930.000
126SLC38A1solute carrier family 38, member 1Liver+2.930.000
127TSC22D3TSC22 domain family, member 3Liver-2.920.000
128AADATaminoadipate aminotransferaseLiver-2.910.000
129HSPB8heat shock 22kDa protein 8Liver+2.900.000
130MYO1Bmyosin IBLiver-2.890.000
131PTGFRNprostaglandin F2 receptor inhibitorLiver+2.880.000
132HINT3histidine triad nucleotide binding protein 3Liver-2.880.006
133ERICH5glutamate-rich 5Liver+2.870.000
134EGR2early growth response 2Liver-2.860.000
135C5orf27chromosome 5 open reading frame 27Liver-2.850.001
136RCL1RNA terminal phosphate cyclase-like 1Liver-2.850.000
137CCDC102Bcoiled-coil domain containing 102BLiver+2.850.000
138MFSD6major facilitator superfamily domain containing 6Liver+2.830.000
139SLC35C1solute carrier family 35 (GDP-fucose transporter), member C1Liver+2.830.000
140BCHEbutyrylcholinesteraseLiver-2.820.001
141B3GNT5UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5Liver+2.820.000
142TMCO3transmembrane and coiled-coil domains 3Liver+2.810.000
143LAMA2laminin, alpha 2Liver+2.810.000
144KIAA0101KIAA0101Liver+2.800.000
145RHOBras homolog family member BLiver-2.800.000
146SLC25A25solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25Liver-2.790.000
147SLC19A2solute carrier family 19 (thiamine transporter), member 2Liver-2.780.000
148BCAT1branched chain amino-acid transaminase 1, cytosolicLiver+2.780.000
149CXCL10chemokine (C-X-C motif) ligand 10Liver+2.780.001
150ETNK2ethanolamine kinase 2Liver-2.770.001
151MOXD1monooxygenase, DBH-like 1Liver+2.770.000
152PPM1Kprotein phosphatase, Mg2+/Mn2+ dependent, 1KLiver-2.760.000
153SDCBP2syndecan binding protein (syntenin) 2Liver+2.740.000
154EMP1epithelial membrane protein 1Liver+2.730.001
155CHST9carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9Liver+2.730.000
156ACSM3acyl-CoA synthetase medium-chain family member 3Liver-2.720.000
157CLIC6chloride intracellular channel 6Liver+2.720.002
158TYMSthymidylate synthetaseLiver+2.720.000
159CAPGcapping protein (actin filament), gelsolin-likeLiver+2.720.000
160CAP2CAP, adenylate cyclase-associated protein, 2 (yeast)Liver+2.720.000
161AASSaminoadipate-semialdehyde synthaseLiver-2.720.002
162COL5A2collagen, type V, alpha 2Liver+2.710.000
163LUMlumicanLiver+2.710.000
164F13A1coagulation factor XIII, A1 polypeptideLiver+2.710.000
165FABP5fatty acid binding protein 5 (psoriasis-associated)Liver+2.710.002
166GPLD1glycosylphosphatidylinositol specific phospholipase D1Liver-2.700.000
167KRT19keratin 19Liver+2.700.012
168ZWINTZW10 interacting kinetochore proteinLiver+2.690.000
169TTC36tetratricopeptide repeat domain 36Liver-2.680.000
170EPDR1ependymin related 1Liver+2.680.000
171PER2period circadian clock 2Liver-2.680.000
172ASNSasparagine synthetase (glutamine-hydrolyzing)Liver+2.680.000
173HSPD1heat shock 60kDa protein 1 (chaperonin)Liver-2.670.000
174RARRES1retinoic acid receptor responder (tazarotene induced) 1Liver+2.670.000
175SLC12A2solute carrier family 12 (sodium/potassium/chloride transporter), member 2Liver+2.670.000
176NFIL3nuclear factor, interleukin 3 regulatedLiver-2.670.000
177CYR61cysteine-rich, angiogenic inducer, 61Liver-2.660.000
178CXCL2chemokine (C-X-C motif) ligand 2Liver-2.660.000
179RNASE1ribonuclease, RNase A family, 1 (pancreatic)Liver+2.660.000
180GLYATglycine-N-acyltransferaseLiver-2.650.001
181PCDH17protocadherin 17Liver+2.650.000
182TP53I3tumor protein p53 inducible protein 3Liver+2.640.000
183LCATlecithin-cholesterol acyltransferaseLiver-2.640.000
184FCN2ficolin (collagen/fibrinogen domain containing lectin) 2Liver-2.630.000
185FMO5flavin containing monooxygenase 5Liver-2.630.000
186CDK1cyclin-dependent kinase 1Liver+2.630.001
187LDLRlow density lipoprotein receptorLiver-2.630.000
188FAM169Afamily with sequence similarity 169, member ALiver+2.620.000
189TENM1teneurin transmembrane protein 1Liver-2.620.000
190TGDSTDP-glucose 4,6-dehydrataseLiver-2.620.000
191SERPINE2serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2Liver+2.620.001
192CETPcholesteryl ester transfer protein, plasmaLiver-2.610.001
193DHRS2dehydrogenase/reductase (SDR family) member 2Liver-2.610.018
194SULT1C2sulfotransferase family, cytosolic, 1C, member 2Liver+2.600.001
195TPM1tropomyosin 1 (alpha)Liver+2.600.000
196MT1Fmetallothionein 1FLiver-2.600.002
197BEX2brain expressed X-linked 2Liver+2.590.000
198SUSD2sushi domain containing 2Liver+2.580.000
199SPIDRscaffolding protein involved in DNA repairLiver-2.580.000
200RORCRAR-related orphan receptor CLiver-2.570.000
201C12orf75chromosome 12 open reading frame 75Liver+2.560.001
202IL13RA2interleukin 13 receptor, alpha 2Liver-2.540.004
203PDGFAplatelet-derived growth factor alpha polypeptideLiver+2.530.000
204PER1period circadian clock 1Liver-2.530.000
205PRKAA2protein kinase, AMP-activated, alpha 2 catalytic subunitLiver+2.530.000
206GPNMBglycoprotein (transmembrane) nmbLiver+2.520.002
207KCNJ3potassium inwardly-rectifying channel, subfamily J, member 3Liver-2.520.000
208RHEBRas homolog enriched in brainLiver-2.510.000
209SPINT1serine peptidase inhibitor, Kunitz type 1Liver+2.510.010
210FCGR1BFc fragment of IgG, high affinity Ib, receptor (CD64)Liver+2.510.002
211CEBPDCCAAT/enhancer binding protein (C/EBP), deltaLiver-2.500.000
212FAM151Afamily with sequence similarity 151, member ALiver-2.500.001
213THRSPthyroid hormone responsiveLiver-2.490.021
214TRIB1tribbles pseudokinase 1Liver-2.490.000
215FBN1fibrillin 1Liver+2.480.000
216TREM2triggering receptor expressed on myeloid cells 2Liver+2.480.002
217SRPX2sushi-repeat containing protein, X-linked 2Liver+2.480.001
218MORC4MORC family CW-type zinc finger 4Liver+2.470.000
219NR5A2nuclear receptor subfamily 5, group A, member 2Liver-2.470.001
220ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila)Liver+2.470.012
221CAPN3calpain 3, (p94)Liver-2.470.000
222G6PCglucose-6-phosphatase, catalytic subunitLiver-2.460.001
223UPB1ureidopropionase, betaLiver-2.460.000
224KLF9Kruppel-like factor 9Liver-2.460.000
225ADRA1Aadrenoceptor alpha 1ALiver-2.460.000
226RNF125ring finger protein 125, E3 ubiquitin protein ligaseLiver-2.450.000
227SLC26A2solute carrier family 26 (anion exchanger), member 2Liver+2.450.000
228ACKR3atypical chemokine receptor 3Liver+2.450.008
229VIPR1vasoactive intestinal peptide receptor 1Liver-2.440.000
230DTLdenticleless E3 ubiquitin protein ligase homolog (Drosophila)Liver+2.440.002
231ESR1estrogen receptor 1Liver-2.440.016
232ADRB2adrenoceptor beta 2, surfaceLiver-2.440.000
233IL1RNinterleukin 1 receptor antagonistLiver-2.440.000
234ECT2epithelial cell transforming 2Liver+2.440.000
235RAPH1Ras association (RalGDS/AF-6) and pleckstrin homology domains 1Liver-2.440.000
236AJUBAajuba LIM proteinLiver+2.430.000
237PLXNC1plexin C1Liver+2.430.000
238CIDECcell death-inducing DFFA-like effector cLiver+2.420.000
239ELOVL7ELOVL fatty acid elongase 7Liver+2.420.007
240MAP1Bmicrotubule-associated protein 1BLiver+2.420.000
241PROM1prominin 1Liver+2.420.014
242SEL1L3sel-1 suppressor of lin-12-like 3 (C. elegans)Liver+2.410.000
243GPR126G protein-coupled receptor 126Liver-2.410.000
244SLC22A15solute carrier family 22, member 15Liver+2.410.000
245ADAMTS2ADAM metallopeptidase with thrombospondin type 1 motif, 2Liver+2.410.000
246ITGA6integrin, alpha 6Liver+2.410.000
247CENPUcentromere protein ULiver+2.410.007
248INSIG1insulin induced gene 1Liver-2.410.005
249SOCS2suppressor of cytokine signaling 2Liver-2.400.002
250PCSK6proprotein convertase subtilisin/kexin type 6Liver-2.400.001
251KLF6Kruppel-like factor 6Liver-2.400.000
252DAKdihydroxyacetone kinase 2 homolog (S. cerevisiae)Liver-2.390.000
253IGFBP1insulin-like growth factor binding protein 1Liver-2.390.000
254ZNF385Bzinc finger protein 385BLiver-2.380.002
255PFKPphosphofructokinase, plateletLiver+2.370.004
256LPLlipoprotein lipaseLiver+2.370.029
257N4BP2L1NEDD4 binding protein 2-like 1Liver-2.370.000
258ARHGEF26Rho guanine nucleotide exchange factor (GEF) 26Liver-2.370.000
259SCG5secretogranin V (7B2 protein)Liver-2.360.000
260SULT1E1sulfotransferase family 1E, estrogen-preferring, member 1Liver-2.360.020
261ZGPATzinc finger, CCCH-type with G patch domainLiver-2.350.011
262FGF13fibroblast growth factor 13Liver+2.350.002
263S100A6S100 calcium binding protein A6Liver+2.350.005
264SORT1sortilin 1Liver+2.340.000
265KRT18keratin 18Liver+2.340.000
266SYBUsyntabulin (syntaxin-interacting)Liver-2.340.000
267VSIG10V-set and immunoglobulin domain containing 10Liver+2.330.000
268FTCDformimidoyltransferase cyclodeaminaseLiver-2.330.000
269FAM126Bfamily with sequence similarity 126, member BLiver-2.330.000
270TMEM139transmembrane protein 139Liver+2.330.000
271CXCL14chemokine (C-X-C motif) ligand 14Liver-2.320.009
272KRT8keratin 8Liver+2.300.000
273IL6Rinterleukin 6 receptorLiver-2.300.000
274VAMP5vesicle-associated membrane protein 5Liver+2.300.000
275IRS2insulin receptor substrate 2Liver-2.300.000
276ENPP2ectonucleotide pyrophosphatase/phosphodiesterase 2Liver+2.300.005
277CDHR5cadherin-related family member 5Liver-2.290.002
278KRT222keratin 222Liver+2.290.001
279GSNgelsolinLiver+2.290.000
280CLDN10claudin 10Liver+2.290.018
281ANXA3annexin A3Liver+2.280.012
282SLCO4C1solute carrier organic anion transporter family, member 4C1Liver-2.270.005
283ANKRD37ankyrin repeat domain 37Liver-2.270.001
284SLC6A1solute carrier family 6 (neurotransmitter transporter), member 1Liver-2.260.000
285ANLNanillin, actin binding proteinLiver+2.250.008
286CHST4carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4Liver+2.250.022
287ANXA5annexin A5Liver+2.250.000
288P4HA2prolyl 4-hydroxylase, alpha polypeptide IILiver+2.250.000
289CLDN7claudin 7Liver+2.250.000
290ADRB1adrenoceptor beta 1Liver-2.250.000
291EPHA3EPH receptor A3Liver+2.250.000
292KPNA2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)Liver+2.250.000
293CYP39A1cytochrome P450, family 39, subfamily A, polypeptide 1Liver-2.240.002
294C8orf4chromosome 8 open reading frame 4Liver-2.240.000
295TEStestis derived transcript (3 LIM domains)Liver+2.240.000
296ACACBacetyl-CoA carboxylase betaLiver-2.240.001
297ASB9ankyrin repeat and SOCS box containing 9Liver-2.230.000
298ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif, 12Liver+2.230.001
299SLC7A1solute carrier family 7 (cationic amino acid transporter, y+ system), member 1Liver+2.220.003
300TESCtescalcinLiver+2.220.006
301CLEC4GC-type lectin domain family 4, member GLiver-2.220.017
302PMEPA1prostate transmembrane protein, androgen induced 1Liver+2.220.006
303RAB3BRAB3B, member RAS oncogene familyLiver+2.210.035
304C12orf5chromosome 12 open reading frame 5Liver+2.210.000
305DIRAS3DIRAS family, GTP-binding RAS-like 3Liver-2.210.000
306SORBS2sorbin and SH3 domain containing 2Liver-2.210.008
307ASPAaspartoacylaseLiver-2.210.000
308PRO2852uncharacterized protein PRO2852Liver-2.200.000
309ADH4alcohol dehydrogenase 4 (class II), pi polypeptideLiver-2.200.010
310CRNDEcolorectal neoplasia differentially expressed (non-protein coding)Liver+2.200.000
311VTCN1V-set domain containing T cell activation inhibitor 1Liver+2.190.010
312TMED3transmembrane emp24 protein transport domain containing 3Liver+2.190.000
313CCNB1cyclin B1Liver+2.180.017
314ACADSBacyl-CoA dehydrogenase, short/branched chainLiver-2.170.000
315ADH6alcohol dehydrogenase 6 (class V)Liver-2.170.002
316CDH6cadherin 6, type 2, K-cadherin (fetal kidney)Liver+2.160.006
317SQSTM1sequestosome 1Liver+2.160.002
318ITGAVintegrin, alpha VLiver+2.150.000
319EHFets homologous factorLiver+2.150.012
320LRRC1leucine rich repeat containing 1Liver+2.150.001
321MAP2microtubule-associated protein 2Liver+2.150.000
322ABCB4ATP-binding cassette, sub-family B (MDR/TAP), member 4Liver+2.150.000
323SPINT2serine peptidase inhibitor, Kunitz type, 2Liver+2.150.010
324C9orf72chromosome 9 open reading frame 72Liver-2.150.000
325BACE2beta-site APP-cleaving enzyme 2Liver+2.140.032
326RAD54L2RAD54-like 2 (S. cerevisiae)Liver-2.140.000
327EDIL3EGF-like repeats and discoidin I-like domains 3Liver+2.140.007
328SPON2spondin 2, extracellular matrix proteinLiver+2.130.000
329SMOC1SPARC related modular calcium binding 1Liver-2.130.000
330RASEFRAS and EF-hand domain containingLiver+2.130.001
331HIST1H2BChistone cluster 1, H2bcLiver+2.130.001
332ANO10anoctamin 10Liver+2.130.000
333HAAO3-hydroxyanthranilate 3,4-dioxygenaseLiver-2.130.001
334CACNA2D1calcium channel, voltage-dependent, alpha 2/delta subunit 1Liver+2.130.000
335HTR2B5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupledLiver+2.130.001
336PDGFDplatelet derived growth factor DLiver+2.130.022
337GPER1G protein-coupled estrogen receptor 1Liver-2.120.000
338ERRFI1ERBB receptor feedback inhibitor 1Liver-2.120.000
339S100A11S100 calcium binding protein A11Liver+2.120.001
340IL18interleukin 18 (interferon-gamma-inducing factor)Liver+2.120.006
341TMEM200Atransmembrane protein 200ALiver+2.120.008
342TXNRD1thioredoxin reductase 1Liver+2.120.000
343SOD2superoxide dismutase 2, mitochondrialLiver+2.110.005
344MTHFD1Lmethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-likeLiver+2.110.001
345ABCB1ATP-binding cassette, sub-family B (MDR/TAP), member 1Liver+2.110.000
346TNFRSF21tumor necrosis factor receptor superfamily, member 21Liver+2.110.001
347FAIMFas apoptotic inhibitory moleculeLiver+2.100.000
348ENAHenabled homolog (Drosophila)Liver+2.100.000
349NPIPB3nuclear pore complex interacting protein family, member B3Liver-2.090.050
350LEPRleptin receptorLiver-2.090.010
351DUSP10dual specificity phosphatase 10Liver-2.080.000
352CYP26A1cytochrome P450, family 26, subfamily A, polypeptide 1Liver-2.070.004
353ELL2elongation factor, RNA polymerase II, 2Liver-2.070.000
354SORDsorbitol dehydrogenaseLiver-2.070.001
355LYVE1lymphatic vessel endothelial hyaluronan receptor 1Liver-2.060.032
356SLC25A37solute carrier family 25 (mitochondrial iron transporter), member 37Liver-2.040.000
357SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 2Liver-2.040.033
358KALRNkalirin, RhoGEF kinaseLiver-2.040.002
359TCP10Lt-complex 10-likeLiver-2.040.002
360ZFAND5zinc finger, AN1-type domain 5Liver-2.040.000
361ST3GAL6ST3 beta-galactoside alpha-2,3-sialyltransferase 6Liver-2.030.000
362RCAN1regulator of calcineurin 1Liver-2.030.001
363CLDN14claudin 14Liver-2.030.000
364ABCC9ATP-binding cassette, sub-family C (CFTR/MRP), member 9Liver-2.020.001
365IGHMimmunoglobulin heavy constant muLiver-2.020.023
366POLR2J2polymerase (RNA) II (DNA directed) polypeptide J2Liver-2.020.015
367FOLH1folate hydrolase (prostate-specific membrane antigen) 1Liver-2.020.005
368FOLH1Bfolate hydrolase 1BLiver-2.020.011
369ADCY1adenylate cyclase 1 (brain)Liver-2.010.017
370PSAT1phosphoserine aminotransferase 1Liver-2.000.006
371SLC6A16solute carrier family 6, member 16Liver-2.000.000
372COBLL1cordon-bleu WH2 repeat protein-like 1Liver-1.980.004
373DGAT2diacylglycerol O-acyltransferase 2Liver-1.980.000
374CUX2cut-like homeobox 2Liver-1.970.008
375ZNF331zinc finger protein 331Liver-1.970.037
376CFPcomplement factor properdinLiver-1.970.001
377IGFALSinsulin-like growth factor binding protein, acid labile subunitLiver-1.960.014
378RALGPS2Ral GEF with PH domain and SH3 binding motif 2Liver-1.960.015
379CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 4Liver-1.960.049
380GPR125G protein-coupled receptor 125Liver-1.960.000
381RAB26RAB26, member RAS oncogene familyLiver-1.950.011
382LOC149703uncharacterized LOC149703Liver-1.940.016
383PLGLB2plasminogen-like B2Liver-1.930.001
384SLC27A5solute carrier family 27 (fatty acid transporter), member 5Liver-1.930.011
385GOLGA4golgin A4Liver-1.920.006
386KCNAB1potassium voltage-gated channel, shaker-related subfamily, beta member 1Liver-1.910.001
387PGLYRP2peptidoglycan recognition protein 2Liver-1.910.049
388C6orf123chromosome 6 open reading frame 123Liver-1.910.005
389TOB1transducer of ERBB2, 1Liver-1.910.035
390PKLRpyruvate kinase, liver and RBCLiver-1.910.006
391SRD5A1steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)Liver-1.900.002
392SLC22A1solute carrier family 22 (organic cation transporter), member 1Liver-1.890.022
393PER3period circadian clock 3Liver-1.890.012
394JUNBjun B proto-oncogeneLiver-1.890.003
395CPEB3cytoplasmic polyadenylation element binding protein 3Liver-1.890.006
396N4BP2L2NEDD4 binding protein 2-like 2Liver-1.880.012
397SLC47A1solute carrier family 47 (multidrug and toxin extrusion), member 1Liver-1.880.001
398MARC1mitochondrial amidoxime reducing component 1Liver-1.870.001
399CMBLcarboxymethylenebutenolidase homolog (Pseudomonas)Liver-1.870.007
400TRPM7transient receptor potential cation channel, subfamily M, member 7Liver-1.870.000

Expression patterns in normal tissues for genes affiliated with Alcoholic Hepatitis

Search GEO for disease gene expression data for Alcoholic Hepatitis.

Pathways for genes affiliated with Alcoholic Hepatitis

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Pathways related to Alcoholic Hepatitis according to GeneCards/GeneDecks:

(show all 34)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Calcium signaling in the CD4+ TCR pathway37
9.5TNF, IL8
29.5TNF, IL8
39.5IL8, TNF
4
Show member pathways
9.4IL8, ICAM1
59.4IL8, ICAM1
69.3ICAM1, TNF
79.3TNF, ICAM1
8
Show member pathways
9.2IL8, TNF, CYP2E1
9
Show member pathways
IL27-mediated signaling events37
9.1TNF, IL10
109.1TNF, IL10
11
Show member pathways
9.1IL10, TNF
129.1IL10, TNF
139.0IL10, ICAM1
14
Show member pathways
thioredoxin pathway37
9.0ICAM1, TNF, F2
15
Show member pathways
8.9IL8, ICAM1, TNF
168.9TNF, ICAM1, IL8
178.9TNF, ICAM1, IL8
188.9TNF, ICAM1, IL8
198.9TNF, ICAM1, IL8
20
Show member pathways
IL23-mediated signaling events37
Immune response IL 10 signaling pathway59
Angiopoietin receptor Tie2-mediated signaling37
Development PDGF signaling via STATs and NF kB59
Development Angiopoietin Tie2 signaling59
8.8IL10, TNF, F2
218.7IL8, IL10, TNF
228.7IL8, IL10, TNF
238.7TNF, IL10, IL8
24
Show member pathways
Toll-like receptor signaling pathway37
Regulation of toll-like receptor signaling pathway37
8.7TNF, IL10, IL8
258.7TNF, IL10, IL8
26
Show member pathways
8.6IL10, IL22, TNF
27
Show member pathways
8.5TNF, ICAM1, IL10
288.5TNF, ICAM1, IL10
29
Show member pathways
7.7TNF, IL22, IL10, IL8, HGF
30
Show member pathways
7.7TNF, IL22, IL10, IL8, HGF
31
Show member pathways
7.7TNF, IL22, IL10, IL8, HGF
327.6HGF, IL8, IL10, ICAM1, TNF
33
Show member pathways
7.4F2, TNF, IL22, IL10, IL8, HGF
34
Show member pathways
7.4F2, TNF, IL22, IL10, IL8, HGF

Compounds for genes affiliated with Alcoholic Hepatitis

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Compounds related to Alcoholic Hepatitis according to GeneCards/GeneDecks:

(show top 50)    (show all 163)
idCompoundScoreTop Affiliating Genes
1n-tosyl-l-phenylalanine chloromethyl ketone449.3IL8, ICAM1, TNF
2azithromycin44 1210.3IL8, IL10, F2
3staurosporin449.1TNF, ICAM1, IL8
4gabexate mesilate449.1IL8, TNF, IL10
5toxin-1449.1IL10, IL8, TNF
6mip 1alpha449.1IL10, IL8, TNF
7egcg449.0TNF, HGF, CYP2E1, IL8
8il-12449.0TNF, IL10, IL8
95 aminosalicylic acid449.0TNF, IL8, IL10
10diphenyleneiodonium449.0CYP2E1, TNF, ICAM1, IL8
11cdp571448.9IL10, ICAM1, TNF
12imiquimod44 60 29 1211.9TNF, IL8, IL10
13interferon gamma448.9TNF, ICAM1, IL10
14ciglitazone44 299.9IL8, ICAM1, TNF
15hyaluronic acid44 259.9F2, ICAM1, HGF, IL8
16pdtc448.9ICAM1, TNF, HGF, IL8
17aprotinin44 129.8IL10, HGF, IL8, F2
18sp 60012544 609.8IL8, ICAM1, TNF, HGF
19triptolide448.8IL8, ICAM1, TNF
20natalizumab44 129.8TNF, ICAM1, IL10
21mg 13244 609.8IL8, HGF, ICAM1, TNF
22herbimycin a44 609.7TNF, HGF, IL8, ICAM1
23thalidomide44 50 60 1211.7TNF, HGF, IL10, CYP2E1
24go 697644 609.6IL8, TNF, ICAM1
25hydrocortisone44 3 60 1211.6IL8, IL10, HGF, TNF
26ulinastatin448.6TNF, ICAM1, IL10, IL8
27polymyxin b448.5IL10, ICAM1, TNF, IL8
28groalpha448.5IL10, ICAM1, IL8, TNF
29gm-csf44 299.5ICAM1, TNF, IL8, IL10
30n acetylcysteine448.5HGF, IL8, ICAM1, F2, TNF
318-isoprostane448.5IL10, ICAM1, IL8, TNF
32tarc448.5IL8, TNF, ICAM1, IL10
33ccl344 299.5IL8, IL10, ICAM1, TNF
34okt3448.5ICAM1, IL10, TNF
35neopterin448.5TNF, ICAM1, IL10, IL8
36genistein44 29 60 3 25 1213.4HGF, IL8, ICAM1, TNF, CYP2E1
37endotoxin448.3IL8, IL10, ICAM1, TNF
38simvastatin44 50 60 29 25 1213.2F2, TNF, IL8, ICAM1, IL10
39lactate448.2CYP2E1, TNF, ICAM1, F2, IL8, HGF
40pentoxifylline44 129.2IL8, IL10, ICAM1, TNF, CYP2E1
41prostacyclin448.2TNF, ICAM1, HGF, IL10
42h2o2448.2IL8, CYP2E1, ICAM1, TNF, HGF
43histamine44 29 2510.0TNF, ICAM1, IL10, IL8, HGF
44ly294002448.0TNF, HGF, IL8, ICAM1, IL10
45pge2448.0HGF, IL10, ICAM1, IL8, TNF
46oxygen44 258.9IL22, CYP2E1, ICAM1, TNF, IL8, HGF
47cycloheximide447.8TNF, IL10, HGF, IL8, ICAM1
48cyclosporin a44 29 609.7HGF, IL8, IL10, TNF, F2, ICAM1
49sb 20358044 608.7HGF, CYP2E1, TNF, IL8, IL10, ICAM1
50dexamethasone44 50 29 1210.7ICAM1, IL10, IL8, HGF, CYP2E1, TNF

GO Terms for genes affiliated with Alcoholic Hepatitis

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Cellular components related to Alcoholic Hepatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.2F2, TNF, IL22, IL8, HGF
2extracellular spaceGO:0056156.5F2, TNF, ICAM1, IL22, IL10, IL8

Biological processes related to Alcoholic Hepatitis according to GeneCards/GeneDecks:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1embryonic digestive tract developmentGO:0485669.8TNF, IL8
2acute-phase responseGO:0069539.7F2, IL22
3calcium-mediated signalingGO:0197229.6IL8, TNF
4cellular response to interleukin-1GO:0713479.6IL8, ICAM1
5positive regulation of phosphatidylinositol 3-kinase signalingGO:0140689.6F2, HGF
6response to molecule of bacterial originGO:0022379.5IL8, IL10
7positive regulation of nitric oxide biosynthetic processGO:0454299.5ICAM1, TNF
8receptor biosynthetic processGO:0328009.5IL10, TNF
9regulation of cell adhesionGO:0301559.4IL8, ICAM1
10negative regulation of cytokine secretion involved in immune responseGO:0027409.4TNF, IL10
11negative regulation of growth of symbiont in hostGO:0441309.4IL10, TNF
12positive regulation of peptidyl-tyrosine phosphorylationGO:0507319.4HGF, ICAM1
13negative regulation of interleukin-6 productionGO:0327159.4IL10, TNF
14positive regulation of cytokine secretionGO:0507159.4IL10, TNF
15response to activityGO:0148239.3TNF, IL10
16cellular response to tumor necrosis factorGO:0713569.1IL8, ICAM1
17cellular response to lipopolysaccharideGO:0712228.9ICAM1, IL10, IL8
18response to glucocorticoidGO:0513848.9IL10, IL22, TNF
19inflammatory responseGO:0069548.5IL8, IL10, IL22, TNF
20response to drugGO:0424938.5CYP2E1, TNF, ICAM1, IL10

Molecular functions related to Alcoholic Hepatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:0051258.6IL10, IL22, TNF
2growth factor activityGO:0080838.6HGF, IL10, F2

Products for genes affiliated with Alcoholic Hepatitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Alcoholic Hepatitis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet