MCID: ALC006
MIFTS: 58

Alcoholic Hepatitis malady

Gastrointestinal diseases, Liver diseases categories

Summaries for Alcoholic Hepatitis

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Wikipedia:63 Alcoholic hepatitis is hepatitis (inflammation of the liver) due to excessive intake of alcohol. It is... more...

MalaCards based summary: Alcoholic Hepatitis, also known as acute alcoholic liver disease, is related to hepatitis and hepatorenal syndrome. An important gene associated with Alcoholic Hepatitis is F2 (coagulation factor II (thrombin)), and among its related pathways are Calcineurin-regulated NFAT-dependent transcription in lymphocytes and Legionellosis. The compounds n-tosyl-l-phenylalanine chloromethyl ketone and azithromycin have been mentioned in the context of this disorder. Affiliated tissues include eye, liver and brain, and related mouse phenotypes are no phenotypic analysis and liver/biliary system.

Aliases & Classifications for Alcoholic Hepatitis

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Alcoholic Hepatitis, Aliases & Descriptions:

Name: Alcoholic Hepatitis 30 9
Acute Alcoholic Liver Disease 9 60
Acute Alcoholic Hepatitis 9 43
 
Hepatitis, Alcoholic 60
Hepatitis Alcoholic 43


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases, Liver diseases


External Ids:

Disease Ontology9 DOID:12351
NCIt38 C34352
SNOMED-CT55 9953008, 155810001
ICD9CM27 571.1
ICD1025 K70.1

Related Diseases for Alcoholic Hepatitis

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Diseases related to Alcoholic Hepatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 104)
idRelated DiseaseScoreTop Affiliating Genes
1hepatitis32.3CYP2E1, F2, HGF
2hepatorenal syndrome31.3F2
3hepatitis c30.6CYP2E1, IL10, F2
4hepatitis b30.6F2, IL10
5liver cirrhosis30.5CYP2E1, F2, HGF
6alcoholic liver cirrhosis30.5CYP2E1, F2, IL8
7acute liver failure30.4F2, HGF
8peritonitis30.2F2, TNF
9liver disease30.1IL10, TNF, CYP2E1, ICAM1, F2
10acute pancreatitis29.9IL10, IL8
11pancreatitis29.8CYP2E1, ICAM1, IL10
12pneumonia29.3IL22, IL10, TNF, IL8, ICAM1
13hepatitis a10.7
14blindness10.4
15blau syndrome10.4TNF
16hepatitis c virus10.4
17interstitial lung disease10.4TNF
18meningitis10.4IL8
19leukostasis10.4ICAM1
20rheumatoid vasculitis10.4ICAM1
21leukemoid reaction10.3
22nonalcoholic steatohepatitis10.3
23leishmaniasis10.3IL10
24chorioamnionitis10.2TNF, IL8
25arthritis10.2IL8, TNF
26hepatic encephalopathy10.2
27galactosemia10.2HGF, F2
28acute respiratory distress syndrome10.2TNF, IL8
29common cold10.2ICAM1, IL8
30allergic rhinitis10.2ICAM1, IL8
31cork-handlers' disease10.2IL8, F2
32behcet's disease10.2IL8, TNF
33vernal keratoconjunctivitis10.2IL8, ICAM1
34arteriosclerosis obliterans10.2ICAM1, HGF
35thrombocytopenia10.1
36portal hypertension10.1
37esophagitis10.1
38arteriosclerosis10.1ICAM1, HGF
39rhinitis10.1ICAM1, IL8
40hepatoblastoma10.1CYP2E1, HGF
41pulmonary sarcoidosis10.1ICAM1, TNF
42respiratory failure10.1ICAM1, TNF
43pregnancy loss, recurrent 110.1F2, IL10
44monocytic leukemia10.1TNF, IL8
45pulmonary disease, chronic obstructive10.1IL8, TNF, CYP2E1
46periodontal disease10.1TNF, IL8
47acute graft versus host disease10.0IL10, TNF
48demyelinating disease10.0IL10, TNF
49microvascular complications of diabetes 110.0ICAM1, HGF, IL8
50vasculitis10.0ICAM1, TNF, F2

Graphical network of the top 20 diseases related to Alcoholic Hepatitis:



Diseases related to alcoholic hepatitis

Symptoms for Alcoholic Hepatitis

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Drugs & Therapeutics for Alcoholic Hepatitis

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Drug clinical trials:

Search ClinicalTrials for Alcoholic Hepatitis

Search NIH Clinical Center for Alcoholic Hepatitis

Genetic Tests for Alcoholic Hepatitis

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Anatomical Context for Alcoholic Hepatitis

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MalaCards organs/tissues related to Alcoholic Hepatitis:

31
Eye, Liver, Brain, Neutrophil, T cells, Retina, Colon, Adipocyte, Breast, Placenta, Myeloid, Monocytes, Pituitary, Kidney, Testes, Bone, Whole blood, Thyroid, Prostate, Endothelial

Animal Models for Alcoholic Hepatitis or affiliated genes

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MGI Mouse Phenotypes related to Alcoholic Hepatitis:

35 (show all 13)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030128.1HGF, IL10, IL22, TNF
2MP:00053708.0CYP2E1, TNF, IL22, IL10, HGF
3MP:00053888.0F2, TNF, IL22, IL10
4MP:00020067.9CYP2E1, TNF, ICAM1, IL22, IL10
5MP:00053817.8F2, TNF, ICAM1, IL22, IL10
6MP:00107717.8F2, TNF, ICAM1, IL22, IL10
7MP:00053847.7HGF, IL10, ICAM1, TNF, F2
8MP:00053857.6F2, CYP2E1, TNF, ICAM1, IL10, HGF
9MP:00053877.4F2, TNF, ICAM1, IL22, IL10, IL8
10MP:00053767.3F2, CYP2E1, TNF, ICAM1, IL22, IL10
11MP:00053787.3F2, TNF, ICAM1, IL22, IL10, HGF
12MP:00053977.0HGF, IL8, IL10, IL22, ICAM1, TNF
13MP:00107687.0F2, CYP2E1, TNF, ICAM1, IL22, IL10

Publications for Alcoholic Hepatitis

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Articles related to Alcoholic Hepatitis:

(show top 50)    (show all 542)
idTitleAuthorsYear
1
TLR3/4 signaling is mediated via the NFI_B-CXCR4/7 pathway in human alcoholic hepatitis and non-alcoholic steatohepatitis which formed Mallory-Denk bodies. (24997224)
2014
2
Assessment of the Model for End-stage Liver Disease (MELD) Score in Predicting Prognosis of Patients with Alcoholic Hepatitis. (25755531)
2014
3
Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis. (22278680)
2012
4
Molecular targets in the treatment of alcoholic hepatitis. (23112542)
2012
5
Severe acute alcoholic hepatitis and hepatorenal syndrome: role of transjugular intrahepatic portosystemic stent shunt. (22802893)
2012
6
Severe alcoholic hepatitis: glucocorticoid saves lives and transplantation is promising. (21633648)
2011
7
Definition, epidemiology and magnitude of alcoholic hepatitis. (21731902)
2011
8
Development of multiple peribiliary cysts following acute alcoholic hepatitis. (20658328)
2010
9
The place of liver transplantation in the treatment of severe alcoholic hepatitis. (20347501)
2010
10
Alcoholic hepatitis 2010: a clinician's guide to diagnosis and therapy. (20954276)
2010
11
Acetate, the key modulator of inflammatory responses in acute alcoholic hepatitis. (20232292)
2010
12
Glucocorticoids can help in acute severe alcoholic hepatitis. (19566906)
2009
13
Alcoholic hepatitis. (19812414)
2009
14
Antioxidants plus corticosteroids in the treatment of severe acute alcoholic hepatitis: the question is still open. (18486264)
2008
15
Alcoholic hepatitis with leukemoid reaction after surgery. (16368495)
2006
16
Future use of the Glasgow alcoholic hepatitis score. (16344584)
2006
17
Regulation of fat metabolism in the liver: link to non-alcoholic hepatic steatosis and impact of physical exercise. (16649140)
2006
18
Current concepts and controversies in the treatment of alcoholic hepatitis. (17109510)
2006
19
Duplex Doppler ultrasound of the hepatic artery in patients with acute alcoholic hepatitis. (11960073)
2002
20
Role of Kupffer cells in alcoholic hepatitis. (12062631)
2002
21
Is pentoxifylline the answer for alcoholic hepatitis? (12170912)
2002
22
Influence of superimposed alcoholic hepatitis on the outcome of liver transplantation for end-stage alcoholic liver disease. (12044530)
2002
23
Free radicals, chemokines, and cell injury in HIV-1 and SIV infections and alcoholic hepatitis. (11744325)
2001
24
Serum laminin and type IV collagen are accurate markers of histologically severe alcoholic hepatitis in patients with cirrhosis. (10735610)
2000
25
Antioxidants attenuate nuclear factor-kappa B activation and tumor necrosis factor-alpha production in alcoholic hepatitis patient monocytes and rat Kupffer cells, in vitro. (10614719)
1999
26
Nonalcoholic steatohepatitis. Clinicopathological comparison with alcoholic hepatitis in ambulatory and hospitalized patients. (8565753)
1996
27
Prognostic factors for short-term survival in alcoholic hepatitis in Japan: analysis by logistic regression. (8986243)
1996
28
Protein energy malnutrition in severe alcoholic hepatitis: diagnosis and response to treatment. The VA Cooperative Study Group #275. (8523623)
1995
29
Lack of plasma complement activation in severe acute alcoholic hepatitis. (8749823)
1995
30
Liver transplantation for alcoholic liver disease: survival of patients transplanted with alcoholic hepatitis plus cirrhosis as compared with those with cirrhosis alone. (8279673)
1993
31
Immunoglobulin A antibody to a 200-kilodalton cytosolic acetaldehyde adduct in alcoholic hepatitis. (1451979)
1992
32
Corticosteroids and alcoholic hepatitis. (1824838)
1991
33
A randomized, controlled trial of treatment of alcoholic hepatitis with parenteral nutrition and oxandrolone. II. Short-term effects on nitrogen metabolism, metabolic balance, and nutrition. (1909086)
1991
34
Do corticosteroids reduce mortality from alcoholic hepatitis? A meta-analysis of the randomized trials. (2142869)
1990
35
Increased plasma tumor necrosis factor in severe alcoholic hepatitis. (2339855)
1990
36
Alcoholic hepatitis: pathogenesis and approaches to treatment. (2237274)
1990
37
Corticosteroid therapy of alcoholic hepatitis: how many studies will it take? (2205560)
1990
38
Tumor necrosis factor in alcoholic hepatitis. (2777030)
1989
39
Metabolic effects of enteral formula feeding in alcoholic hepatitis. (3119452)
1987
40
Morphometric study of hepatic ultrastructure in alcoholic hepatitis. Veterans Administration Cooperative Study Group on Alcoholic Hepatitis. (2980746)
1987
41
Plasma lipoprotein composition in alcoholic hepatitis: accumulation of apolipoprotein E-rich high density lipoprotein and preferential reappearance of "light'-HDL during partial recovery. (7097121)
1982
42
Double-blind, controlled trial of propylthiouracil in patients with severe acute alcoholic hepatitis. (7037524)
1982
43
Acute alcoholic hepatitis: clinical, biochemical and liver scintiscanning correlation in assessing prognosis. (472544)
1979
44
Hyperalimentation in alcoholic hepatitis. (119434)
1979
45
The role of lecithin:cholesterol acyltransferase deficiency in the apoprotein metabolism of alcoholic hepatitis. (746350)
1978
46
Immunological aspects of alcoholic hepatitis. (95720)
1978
47
Alcoholic hepatitis. (644352)
1978
48
Lymphocyte cytotoxicity in alcoholic hepatitis. (65306)
1977
49
Editorial: Alcoholic hepatitis and corticosteroids. (4751745)
1973
50
Prednisone therapy of acute alcoholic hepatitis. Report of a controlled trial. (4751740)
1973

Variations for Alcoholic Hepatitis

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Expression for genes affiliated with Alcoholic Hepatitis

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LifeMap Discovery
Genes differentially expressed in tissues of Alcoholic Hepatitis patients vs. healthy controls: 30 (show all 66)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1AKR1B10aldo-keto reductase family 1, member B10 (aldose reductase)Liver+8.790.000
2KRT23keratin 23 (histone deacetylase inducible)Liver+7.040.000
3CCL20chemokine (C-C motif) ligand 20Liver+6.560.000
4SPINK1serine peptidase inhibitor, Kazal type 1Liver+6.070.000
5SPP1secreted phosphoprotein 1Liver+6.040.000
6LCN2lipocalin 2Liver+5.740.000
7CXCL6chemokine (C-X-C motif) ligand 6Liver+5.550.000
8COL1A2collagen, type I, alpha 2Liver+5.330.000
9LOXL4lysyl oxidase-like 4Liver+5.010.000
10PDZK1IP1PDZK1 interacting protein 1Liver+4.950.000
11GOLM1golgi membrane protein 1Liver+4.870.000
12MMP7matrix metallopeptidase 7 (matrilysin, uterine)Liver+4.730.000
13EFEMP1EGF containing fibulin-like extracellular matrix protein 1Liver+4.630.000
14CD24CD24 moleculeLiver+4.570.000
15TACSTD2tumor-associated calcium signal transducer 2Liver+4.410.000
16DCDC2doublecortin domain containing 2Liver+4.280.000
17EPCAMepithelial cell adhesion moleculeLiver+4.260.000
18NQO1NAD(P)H dehydrogenase, quinone 1Liver+4.100.000
19SOX9SRY (sex determining region Y)-box 9Liver+3.990.000
20THBS2thrombospondin 2Liver+3.980.000
21KRT7keratin 7Liver+3.960.000
22BICC1BicC family RNA binding protein 1Liver+3.960.000
23FABP4fatty acid binding protein 4, adipocyteLiver+3.940.000
24IL32interleukin 32Liver+3.940.000
25RRM2ribonucleotide reductase M2Liver+3.900.000
26IL8interleukin 8Liver+3.900.000
27VCANversicanLiver+3.900.000
28COL1A1collagen, type I, alpha 1Liver+3.890.000
29COL5A1collagen, type V, alpha 1Liver+3.770.000
30RGS4regulator of G-protein signaling 4Liver+3.760.000
31STMN2stathmin 2Liver+3.720.000
32SOX4SRY (sex determining region Y)-box 4Liver+3.710.000
33ANXA2annexin A2Liver+3.670.000
34ADAMTS18ADAM metallopeptidase with thrombospondin type 1 motif, 18Brain-3.660.005
35ANXA2P2annexin A2 pseudogene 2Liver+3.660.000
36DTNAdystrobrevin, alphaLiver+3.620.000
37FAT1FAT atypical cadherin 1Liver+3.590.000
38C15orf48chromosome 15 open reading frame 48Liver+3.560.000
39CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)Liver+3.510.000
40ACSL4acyl-CoA synthetase long-chain family member 4Liver+3.510.000
41CTHRC1collagen triple helix repeat containing 1Liver+3.500.000
42SLC51Bsolute carrier family 51, beta subunitLiver+3.490.001
43CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)Liver+3.480.000
44KDELR3KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3Liver+3.470.000
45LXNlatexinLiver+3.450.000
46CD109CD109 moleculeLiver+3.400.000
47S100PS100 calcium binding protein PLiver+3.380.014
48COL4A1collagen, type IV, alpha 1Liver+3.370.000
49LGALS3lectin, galactoside-binding, soluble, 3Liver+3.290.000
50GPX2glutathione peroxidase 2 (gastrointestinal)Liver+3.290.000
51AQP1aquaporin 1 (Colton blood group)Liver+3.270.000
52CA12carbonic anhydrase XIILiver+3.250.000
53ANXA13annexin A13Liver+3.210.000
54TNFRSF12Atumor necrosis factor receptor superfamily, member 12ALiver+3.190.000
55KLHL29kelch-like family member 29Liver+3.170.000
56TIMP1TIMP metallopeptidase inhibitor 1Liver+3.150.000
57TRNP1TMF1-regulated nuclear protein 1Liver+3.120.000
58LGALS4lectin, galactoside-binding, soluble, 4Liver+3.110.000
59CDH11cadherin 11, type 2, OB-cadherin (osteoblast)Liver+3.110.000
60CHI3L1chitinase 3-like 1 (cartilage glycoprotein-39)Liver+3.090.010
61COL3A1collagen, type III, alpha 1Liver+3.040.000
62EEF1A2eukaryotic translation elongation factor 1 alpha 2Liver+3.030.001
63PLP2proteolipid protein 2 (colonic epithelium-enriched)Liver+3.030.000
64TAX1BP3Tax1 (human T-cell leukemia virus type I) binding protein 3Liver+3.020.000
65SLC44A3solute carrier family 44, member 3Liver+3.010.000
66PHLDA2pleckstrin homology-like domain, family A, member 2Liver+3.010.000

Search GEO for disease gene expression data for Alcoholic Hepatitis.

Pathways for genes affiliated with Alcoholic Hepatitis

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Pathways related to Alcoholic Hepatitis according to GeneCards Suite gene sharing:

(show all 34)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Calcium signaling in the CD4+ TCR pathway36
9.5TNF, IL8
29.5TNF, IL8
39.5IL8, TNF
4
Show member pathways
9.4IL8, ICAM1
59.4IL8, ICAM1
69.3ICAM1, TNF
79.3TNF, ICAM1
8
Show member pathways
9.2IL8, TNF, CYP2E1
9
Show member pathways
IL27-mediated signaling events36
9.1TNF, IL10
109.1TNF, IL10
11
Show member pathways
9.1IL10, TNF
129.1IL10, TNF
139.0IL10, ICAM1
14
Show member pathways
thioredoxin pathway36
9.0ICAM1, TNF, F2
15
Show member pathways
8.9IL8, ICAM1, TNF
168.9TNF, ICAM1, IL8
178.9TNF, ICAM1, IL8
188.9TNF, ICAM1, IL8
198.9TNF, ICAM1, IL8
20
Show member pathways
IL23-mediated signaling events36
Immune response IL 10 signaling pathway58
Angiopoietin receptor Tie2-mediated signaling36
Development PDGF signaling via STATs and NF kB58
Development Angiopoietin Tie2 signaling58
8.8IL10, TNF, F2
218.7IL8, IL10, TNF
228.7IL8, IL10, TNF
238.7TNF, IL10, IL8
24
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
8.7TNF, IL10, IL8
258.7TNF, IL10, IL8
26
Show member pathways
8.6IL10, IL22, TNF
27
Show member pathways
8.5TNF, ICAM1, IL10
288.5TNF, ICAM1, IL10
29
Show member pathways
7.7TNF, IL22, IL10, IL8, HGF
30
Show member pathways
7.7TNF, IL22, IL10, IL8, HGF
31
Show member pathways
7.7TNF, IL22, IL10, IL8, HGF
327.6HGF, IL8, IL10, ICAM1, TNF
33
Show member pathways
7.4F2, TNF, IL22, IL10, IL8, HGF
34
Show member pathways
7.4F2, TNF, IL22, IL10, IL8, HGF

Compounds for genes affiliated with Alcoholic Hepatitis

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Compounds related to Alcoholic Hepatitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 163)
idCompoundScoreTop Affiliating Genes
1n-tosyl-l-phenylalanine chloromethyl ketone439.3IL8, ICAM1, TNF
2azithromycin43 1210.3IL8, IL10, F2
3staurosporin439.1IL8, TNF, ICAM1
4gabexate mesilate439.1IL10, TNF, IL8
5toxin-1439.1TNF, IL8, IL10
6mip 1alpha439.1IL10, IL8, TNF
7egcg439.0CYP2E1, TNF, IL8, HGF
85 aminosalicylic acid439.0IL10, TNF, IL8
9il-12439.0TNF, IL10, IL8
10diphenyleneiodonium439.0CYP2E1, TNF, ICAM1, IL8
11cdp571438.9IL10, ICAM1, TNF
12interferon gamma438.9TNF, ICAM1, IL10
13imiquimod43 59 28 1211.9IL8, IL10, TNF
14parthenolide43 29.9IL8, ICAM1, TNF
15hyaluronic acid43 249.9HGF, F2, IL8, ICAM1
16pdtc438.9ICAM1, TNF, HGF, IL8
17aprotinin43 129.8IL10, HGF, IL8, F2
18sp 60012543 599.8HGF, IL8, ICAM1, TNF
19go 697643 599.8ICAM1, TNF, IL8
20natalizumab43 129.8TNF, ICAM1, IL10
21mg 13243 599.8TNF, ICAM1, IL8, HGF
22herbimycin a43 599.7ICAM1, HGF, IL8, TNF
23thalidomide43 49 59 1211.7TNF, HGF, IL10, CYP2E1
24triptolide438.6IL8, TNF, ICAM1
25hydrocortisone43 2 59 1211.6HGF, TNF, IL10, IL8
26ulinastatin438.6TNF, ICAM1, IL10, IL8
27polymyxin b438.5IL10, ICAM1, TNF, IL8
28groalpha438.5IL10, ICAM1, IL8, TNF
29gm-csf43 289.5ICAM1, TNF, IL8, IL10
30n acetylcysteine438.5HGF, IL8, ICAM1, F2, TNF
318-isoprostane438.5IL10, ICAM1, IL8, TNF
32tarc438.5IL8, TNF, ICAM1, IL10
33ccl343 289.5IL8, IL10, ICAM1, TNF
34okt3438.5TNF, ICAM1, IL10
35neopterin438.5TNF, ICAM1, IL10, IL8
36genistein43 28 59 2 24 1213.4CYP2E1, TNF, ICAM1, IL8, HGF
37endotoxin438.3IL8, TNF, ICAM1, IL10
38simvastatin43 49 59 28 24 1213.2F2, TNF, IL8, ICAM1, IL10
39lactate438.2CYP2E1, TNF, ICAM1, F2, IL8, HGF
40pentoxifylline43 129.2IL8, IL10, ICAM1, TNF, CYP2E1
41prostacyclin438.2HGF, IL10, ICAM1, TNF
42h2o2438.2TNF, CYP2E1, ICAM1, IL8, HGF
43histamine43 28 2410.0TNF, ICAM1, IL10, IL8, HGF
44ly294002438.0TNF, HGF, ICAM1, IL10, IL8
45pge2438.0TNF, ICAM1, IL10, IL8, HGF
46oxygen43 248.9TNF, IL8, IL22, CYP2E1, HGF, ICAM1
47cycloheximide437.8TNF, IL10, IL8, HGF, ICAM1
48cyclosporin a43 28 599.7HGF, IL8, IL10, TNF, F2, ICAM1
49sb 20358043 598.7HGF, CYP2E1, TNF, IL8, IL10, ICAM1
50dexamethasone43 49 28 1210.7ICAM1, IL10, IL8, HGF, CYP2E1, TNF

GO Terms for genes affiliated with Alcoholic Hepatitis

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Cellular components related to Alcoholic Hepatitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055768.2HGF, IL8, IL22, TNF, F2
2extracellular spaceGO:00056156.5HGF, F2, TNF, ICAM1, IL22, IL10

Biological processes related to Alcoholic Hepatitis according to GeneCards Suite gene sharing:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1embryonic digestive tract developmentGO:00485669.8TNF, IL8
2acute-phase responseGO:00069539.7F2, IL22
3calcium-mediated signalingGO:00197229.6IL8, TNF
4cellular response to interleukin-1GO:00713479.6IL8, ICAM1
5positive regulation of phosphatidylinositol 3-kinase signalingGO:00140689.6F2, HGF
6response to molecule of bacterial originGO:00022379.5IL8, IL10
7positive regulation of nitric oxide biosynthetic processGO:00454299.5ICAM1, TNF
8receptor biosynthetic processGO:00328009.5IL10, TNF
9regulation of cell adhesionGO:00301559.4IL8, ICAM1
10negative regulation of cytokine secretion involved in immune responseGO:00027409.4TNF, IL10
11negative regulation of growth of symbiont in hostGO:00441309.4IL10, TNF
12positive regulation of peptidyl-tyrosine phosphorylationGO:00507319.4HGF, ICAM1
13negative regulation of interleukin-6 productionGO:00327159.4IL10, TNF
14positive regulation of cytokine secretionGO:00507159.4IL10, TNF
15response to activityGO:00148239.3TNF, IL10
16cellular response to tumor necrosis factorGO:00713569.1IL8, ICAM1
17cellular response to lipopolysaccharideGO:00712228.9ICAM1, IL10, IL8
18response to glucocorticoidGO:00513848.9IL10, IL22, TNF
19inflammatory responseGO:00069548.5IL8, IL10, IL22, TNF
20response to drugGO:00424938.5CYP2E1, TNF, ICAM1, IL10

Molecular functions related to Alcoholic Hepatitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:00051258.6IL10, IL22, TNF
2growth factor activityGO:00080838.6HGF, IL10, F2

Products for genes affiliated with Alcoholic Hepatitis

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Sources for Alcoholic Hepatitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet