MCID: ALC009
MIFTS: 49

Alcoholic Liver Cirrhosis malady

Categories: Gastrointestinal diseases, Liver diseases

Aliases & Classifications for Alcoholic Liver Cirrhosis

Aliases & Descriptions for Alcoholic Liver Cirrhosis:

Name: Alcoholic Liver Cirrhosis 38 12 14
Alcoholic Cirrhosis 12 52 14
Portal Cirrhosis 12 52 69
Liver Cirrhosis, Alcoholic 42 69
Laennec's Cirrhosis, Alcoholic 12
Alcoholic Cirrhosis of Liver 12
Laennec's Cirrhosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:14018
ICD10 33 K70.3
ICD9CM 35 571.2
MeSH 42 D008104
NCIt 47 C34782
UMLS 69 C0023891

Summaries for Alcoholic Liver Cirrhosis

MalaCards based summary : Alcoholic Liver Cirrhosis, also known as alcoholic cirrhosis, is related to alcoholic hepatitis and meningitis, and has symptoms including icterus An important gene associated with Alcoholic Liver Cirrhosis is ADH1B (Alcohol Dehydrogenase 1B (Class I), Beta Polypeptide), and among its related pathways/superpathways are Metabolism and Cytochrome P450 - arranged by substrate type. The drugs Losartan and Propranolol have been mentioned in the context of this disorder. Affiliated tissues include Liver, liver and bone, and related phenotype is homeostasis/metabolism.

Related Diseases for Alcoholic Liver Cirrhosis

Diseases related to Alcoholic Liver Cirrhosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 92)
id Related Disease Score Top Affiliating Genes
1 alcoholic hepatitis 29.8 CXCL8 F2 TF
2 meningitis 29.2 CXCL8 CYP2E1 PNPLA3 SLC17A5
3 liver cirrhosis 10.8
4 hepatitis 10.3
5 allopurinol toxicity 10.3 CYP2E1 NAT2
6 nondystrophic myotonia 10.3 ALB F2
7 lethal hydranencephaly-diaphragmatic hernia syndrome 10.2 ADH1B ADH1C CYP2E1
8 freiberg's disease 10.2 ALB F2
9 retinitis pigmentosa 29 10.2 ADH1B ADH1C
10 pharynx carcinoma in situ 10.2 ALB F2
11 uvula cancer 10.2 ALDH2 CYP2E1 GSTM1
12 emery-dreifuss muscular dystrophy, x-linked 10.2 CYP2E1 GSTM1 NAT2
13 microglandular adenosis of breast 10.2 CXCL8 GSTM1
14 male genital organ stricture 10.2 ALB TF
15 capillary leak syndrome 10.2 ALB CXCL8
16 rapsn-related fetal akinesia deformation sequence 10.2 CYP2E1 GSTM1 NAT2
17 bile duct cystadenocarcinoma 10.2 ALB F2
18 cervical adenomyoma 10.1 ADH1B ALDH2 CYP2E1 GSTM1
19 coronary artery dissection, spontaneous 10.1 ALB TF
20 depressed scar 10.1 ALB CXCL8 F2
21 asbestosis 10.1 ALB CXCL8 F2
22 sclerosing adenosis of breast 10.1 ALB CXCL8 F2
23 basal cell carcinoma 3 10.1 ALDH2 CYP2A6 GSTM1
24 pancreatitis 10.1
25 membranoproliferative glomerulonephritis 10.1 ALB F2 TF
26 pigmentation disease 10.1 ALB CXCL8 TF
27 tubular adenocarcinoma 10.1 AHSG F2
28 bicipital tenosynovitis 10.1 ADH4 ALDH2
29 polycystic echinococcosis 10.1 AHSG F2 TF
30 focal epithelial hyperplasia 10.1 AHSG ALB TF
31 duane retraction syndrome 10.1 ALB F2
32 bile duct mucoepidermoid carcinoma 10.1 AHSG ALB TF
33 extratemporal epilepsy 10.1 ADH4 ALDH2
34 handl syndrome 10.1 CXCL8 TF
35 inflammatory bowel disease 6 10.1 ADH1B ADH4
36 hepatocellular carcinoma 10.0
37 peritonitis 10.0
38 childhood malignant hemangiopericytoma 10.0 ALB CXCL8 F2
39 kohler's disease 10.0 ALB F2 SLC17A5
40 infiltrating ureter transitional cell carcinoma 10.0 ALB F2 SLC17A5
41 acute monocytic leukemia 10.0 ALB F2 SLC17A5
42 hereditary alpha tryptasemia syndrome 10.0 ALB F2 SLC17A5
43 congenital hypoplastic anemia 10.0 ALB F2 SLC17A5
44 esophagitis 10.0
45 hepatitis c 10.0
46 noninfectious dermatoses of eyelid 10.0 ALB F2 SLC17A5
47 immune system disease 10.0 AHSG CXCL8 GSTM1
48 epiphora due to excess lacrimation 10.0 F2 TF
49 hepatitis c virus 10.0
50 alopecia 10.0 ALDH2 CYP2E1 SLC17A5 TF

Comorbidity relations with Alcoholic Liver Cirrhosis via Phenotypic Disease Network (PDN): (show all 26)


Acquired Thrombocytopenia Active Peptic Ulcer Disease
Acute Cystitis Acute Kidney Failure
Acute Pancreatitis Alcohol Abuse
Alcoholic Cardiomyopathy Alcoholic Gastritis
Alcoholic Hepatitis Alcoholic Neuropathy
Chronic Congestive Splenomegaly Chronic Kidney Failure
Deficiency Anemia Esophageal Varix
Familial Atrial Fibrillation Fatty Liver Disease
Heart Disease Hepatic Encephalopathy
Hepatocellular Carcinoma Hepatorenal Syndrome
Hypersplenism Iron Deficiency Anemia
Portal Hypertension Protein-Energy Malnutrition
Respiratory Failure Urea Cycle Disorder

Graphical network of the top 20 diseases related to Alcoholic Liver Cirrhosis:



Diseases related to Alcoholic Liver Cirrhosis

Symptoms & Phenotypes for Alcoholic Liver Cirrhosis

UMLS symptoms related to Alcoholic Liver Cirrhosis:


icterus

MGI Mouse Phenotypes related to Alcoholic Liver Cirrhosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.32 ADH1C AHSG ALB ALDH2 CYP2E1 F2

Drugs & Therapeutics for Alcoholic Liver Cirrhosis

Drugs for Alcoholic Liver Cirrhosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 173)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Losartan Approved Phase 4,Phase 3 114798-26-4 3961
2
Propranolol Approved, Investigational Phase 4,Phase 3 525-66-6 4946
3
Ethanol Approved Phase 4,Phase 3,Phase 1,Phase 2 64-17-5 702
4
Spironolactone Approved Phase 4 1952-01-7, 52-01-7 5833
5
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
6
Metformin Approved Phase 4 657-24-9 14219 4091
7
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
8
Pyridoxal Approved, Nutraceutical Phase 4 66-72-8 1050
9
Pyridoxine Approved, Nutraceutical, Vet_approved Phase 4 65-23-6 1054
10
Angiotensin II Phase 4,Phase 3,Phase 1,Phase 2 68521-88-0, 11128-99-7 65143 172198
11 Angiotensin II Type 1 Receptor Blockers Phase 4,Phase 3,Phase 1,Phase 2
12 Angiotensin Receptor Antagonists Phase 4,Phase 3,Phase 1,Phase 2
13 Angiotensinogen Phase 4,Phase 3,Phase 1,Phase 2
14 Anti-Arrhythmia Agents Phase 4,Phase 3
15 Antihypertensive Agents Phase 4,Phase 3,Phase 1,Phase 2
16 Liver Extracts Phase 4,Phase 3,Phase 2,Phase 1
17 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
18 Neurotransmitter Agents Phase 4,Phase 3
19 Micronutrients Phase 4,Phase 3
20 Trace Elements Phase 4,Phase 3
21 Vitamins Phase 4,Phase 3
22 Adrenergic Agents Phase 4,Phase 3
23 Adrenergic Antagonists Phase 4,Phase 3
24 Adrenergic beta-Antagonists Phase 4,Phase 3
25 Vasodilator Agents Phase 4,Phase 3,Phase 2,Phase 1
26 Anti-Infective Agents, Local Phase 4,Phase 3,Phase 2
27 Central Nervous System Depressants Phase 4,Phase 3,Phase 2
28 Natriuretic Agents Phase 4,Phase 3
29 Analgesics Phase 4
30 Anti-Anxiety Agents Phase 4
31 Anticonvulsants Phase 4
32 Antimanic Agents Phase 4
33 Antiparkinson Agents Phase 4
34 calcium channel blockers Phase 4
35 Calcium, Dietary Phase 4
36 Excitatory Amino Acid Antagonists Phase 4
37 Excitatory Amino Acids Phase 4
38 GABA Agents Phase 4
39
gamma-Aminobutyric Acid Phase 4 56-12-2 119
40 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
41 Psychotropic Drugs Phase 4
42 Tranquilizing Agents Phase 4
43 Metadoxine Phase 4
44 Vitamin B 6 Phase 4
45 Vitamin B Complex Phase 4
46 diuretics Phase 4,Phase 2,Phase 3
47 Hormone Antagonists Phase 4,Phase 2,Phase 3
48 Hormones Phase 4,Phase 2,Phase 3
49 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3
50 Diuretics, Potassium Sparing Phase 4

Interventional clinical trials:

(show top 50) (show all 86)
id Name Status NCT ID Phase
1 Prevention of Decompensation in Liver Cirrhosis Unknown status NCT00239096 Phase 4
2 Treatment for Alcohol Dependence With Gabapentin Recruiting NCT02771925 Phase 4
3 Effect of Metadoxine on Oxidative Stress in Non-alcoholic Hepatic Steatosis Recruiting NCT02051842 Phase 4
4 Hemodynamic Effects of Chronic Administration of Spironolactone and/or Propranolol in Alcoholic Cirrhotic Patients Terminated NCT00188045 Phase 4
5 Baclofen in the Treatment of Alcoholic Liver Disease Unknown status NCT01711125 Phase 3
6 Probiotics for Portal Hypertension Unknown status NCT01134692 Phase 3
7 Effect on Liver Histology of Vitamin D in Patients With Non-alcoholic Steatohepatitis Unknown status NCT01623024 Phase 3
8 Tenofovir Versus Lamivudine for Patients of Chronic Hepatitis B With Severe Acute Exacerbation Unknown status NCT01848743 Phase 3
9 Treatment of Severe Alcoholic Hepatitis With Corticoids Plus N Acetyl Cysteine Versus Corticoids Alone Completed NCT00863785 Phase 3
10 Trial for Hepatocellular Carcinoma Adjuvant Treatment by Lipiocis Completed NCT00116454 Phase 3
11 Anti-Fibrotic Effects of Losartan In Nash Evaluation Study Completed NCT01051219 Phase 3
12 Efficacy of Granulocyte Colony-stimulating Factor and Erythropoetin for Patients With Acute-on-chronic Liver Failure Completed NCT01383460 Phase 3
13 A Placebo-Controlled, Double-Blind Study to Confirm the Reversal of Hepatorenal Syndrome Type 1 With Terlipressin Completed NCT01143246 Phase 3
14 REnal Function in Liver Transplantation: Everolimus With Calcineurin Inhibitor (CNI)-Sparing sTrategy Recruiting NCT02115113 Phase 3
15 Proton Radiotherapy Versus Radiofrequency Ablation for Patients With Medium or Large Hepatocellular Carcinoma Recruiting NCT02640924 Phase 3
16 Granulocyte Colony Stimulating Factor And Growth Hormone In Cirrhosis Of Liver: An Open Label Study Recruiting NCT02451033 Phase 2, Phase 3
17 To Study the Effect of Nonselective Beta Blockers in Advanced Stage Liver Disease With Ascites Recruiting NCT02649335 Phase 3
18 SurVival of Lysosomal Acid Lipase Deficiency (LAL-D) Infants Treated With SebelipAse aLfa Active, not recruiting NCT01371825 Phase 2, Phase 3
19 Nalmefene in Patients With Alcoholic Compensated Cirrhosis for the Treatment of Alcohol Dependence. Not yet recruiting NCT02824354 Phase 3
20 Phlebotomy and Risk of Hepatocellular Carcinoma in Patients With Compensated Alcoholic Cirrhosis Terminated NCT01342705 Phase 3
21 Children With Lysosomal Acid Lipase Deficiency Who Previously Received Treatment With SBC-102 Terminated NCT01473875 Phase 2, Phase 3
22 The Effectiveness and Safety for Mesenchymal Stem Cell for Alcoholic Liver Cirrhosis Unknown status NCT01741090 Phase 2
23 REVIVE(Randomized Exploratory Clinical Trial to Evaluate the Safety and Effectiveness of Stem Cell Product in Alcoholic Liver Cirrhosis Patient) Completed NCT01875081 Phase 2
24 Dose Finding Study to Assess Safety and Efficacy of Stem Cells in Liver Cirrhosis Completed NCT01591200 Phase 2
25 Efficacy of Baclofen in the Treatment of Alcohol Addiction Completed NCT00525252 Phase 1, Phase 2
26 A Phase II, Double-blinded, Randomized, Controlled Study to Evaluate the Efficacy and Safety of Vitalliver in Patients With Decompensated Cirrhosis Completed NCT00562783 Phase 2
27 Effect of Candesartan in Alcoholic Liver Fibrosis Completed NCT00990639 Phase 1, Phase 2
28 Antioxidant Replacement Therapy in Patients With Alcohol Abuse Completed NCT00936000 Phase 2
29 Treating Nonalcoholic Steatohepatitis With Pioglitazone Completed NCT00062764 Phase 2
30 Use of F-652 in Patients With Alcoholic Hepatitis Recruiting NCT02655510 Phase 1, Phase 2
31 Selonsertib in Combination With Prednisolone Versus Prednisolone Alone in Participants With Severe Alcoholic Hepatitis (AH) Recruiting NCT02854631 Phase 2
32 Clinical Trial in Infants With Rapidly Progressive Lysosomal Acid Lipase Deficiency Active, not recruiting NCT02193867 Phase 2
33 Long-term Follow-up Study of Livercellgram in Alcoholic Liver Cirrhosis Patients Who Completed Livercellgram Phase 2 Study Enrolling by invitation NCT02806011 Phase 2
34 Effects of Rifaximin in Patients With Acute Alcoholic Hepatitis Enrolling by invitation NCT02116556 Phase 2
35 Pegfilgrastim in Patients With Alcoholic Hepatitis Not yet recruiting NCT02776059 Phase 2
36 Pharmacokinetic and Pharmacodynamic Study of IDN-6556 in ACLF Terminated NCT01937130 Phase 2
37 Pharmacokinetics (PK) of Tipranavir/Ritonavir, Ribavirin, Pegylated Interferon (Peg INF) in Hepatitis C (HCV) Subjects With Mild Hepatic Impairment and in HCV, Hepatitis B (HBV), Hepatitis D Infected Subjects or Alcoholic Cirrhosis With Moderate Hepatic I Completed NCT02259855 Phase 1
38 PeproStat Haemostat Study in Subjects Undergoing Liver Surgery Completed NCT02204930 Phase 1
39 Pilot Study of Pentoxifylline for Hepatopulmonary Syndrome Terminated NCT00593658 Phase 1
40 Pangenomic Study During Alcoholic Cirrhosis Unknown status NCT01065233
41 Prospective Analysis Of Cardiac Function In Cirrhotic Patients By Echocardiography And Its Correlation With Events Unknown status NCT01433848
42 Measurement of Fibrinogen in Patients With Systemic Inflammatory Response Syndrome (SIRS), Sepsis or Chronicle Liver Disease on Intensive Care Units (ICU) Unknown status NCT01169168
43 FGL2/Fibroleukin and Hepatitis C Virus Recurrence Post Liver Transplantation Unknown status NCT00701272
44 Multicentre Prospective Cohort Study of Patients With Chronic Alcoholic and/or Metabolic Liver Disease Unknown status NCT01237574
45 The Efficacy of S-adenosyl Methionine (SAMe) Versus Pentoxiphylline in Patients With Non-alcoholic Steatohepatitis With Fibrosis Unknown status NCT02231333
46 Acupuncture as an Adjunctive Treatment for Hepatitis C Patients Unknown status NCT01750515
47 Volatile Organic Compounds (VOCs) and Liver Diseases Unknown status NCT01279356
48 Sulfation of Bile Acids as a Biomarker for Hepatobiliary Diseases Unknown status NCT01200082
49 Liver Transplantation Versus Alternative Therapies for Patients With Pugh B Alcoholic Cirrhosis Completed NCT00701792
50 Adipose Tissue Involvement in Alcohol-induced Liver Inflammation in Human Completed NCT00388323

Search NIH Clinical Center for Alcoholic Liver Cirrhosis

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Alcoholic Liver Cirrhosis cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Alcoholic Liver Cirrhosis:
Livercellgram, bone marrow-derived mesenchymal stem cells for treatment of alcoholic liver cirrhosis
Embryonic/Adult Cultured Cells Related to Alcoholic Liver Cirrhosis:
Bone marrow-derived mesenchymal stem cells

Cochrane evidence based reviews: liver cirrhosis, alcoholic

Genetic Tests for Alcoholic Liver Cirrhosis

Anatomical Context for Alcoholic Liver Cirrhosis

MalaCards organs/tissues related to Alcoholic Liver Cirrhosis:

39
Liver, Bone, T Cells, Monocytes, Bone Marrow, Small Intestine, B Cells
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Alcoholic Liver Cirrhosis:
id Tissue Anatomical CompartmentCell Relevance
1 Liver Liver Lobule Hepatocytes Affected by disease

Publications for Alcoholic Liver Cirrhosis

Articles related to Alcoholic Liver Cirrhosis:

(show top 50) (show all 238)
id Title Authors Year
1
Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis. ( 27802312 )
2016
2
Henoch-SchAPnlein purpura nephritis and colitis in an adult patient with alcoholic liver cirrhosis. ( 27668165 )
2016
3
Concentrations of fetuin-A, osteoprotegerin and I+-Klotho in patients with alcoholic liver cirrhosis. ( 27882180 )
2016
4
Serum Concentrations of Selected Heavy Metals in Patients with Alcoholic Liver Cirrhosis from the Lublin Region in Eastern Poland. ( 27304961 )
2016
5
Behavior of Oxidative Stress Markers in Alcoholic Liver Cirrhosis Patients. ( 28074118 )
2016
6
CLIF-SOFA score and SIRS are independent prognostic factors in patients with hepatic encephalopathy due to alcoholic liver cirrhosis. ( 27367990 )
2016
7
Aldehyde Dehydrogenase 2 (ALDH2) Polymorphism and the Risk of Alcoholic Liver Cirrhosis among East Asians: A Meta-Analysis. ( 27189280 )
2016
8
Letter to the editor: treatment for superficial esophageal cancer with rectal varices bleeding in a patient with alcoholic liver cirrhosis. ( 26728025 )
2016
9
Lispro insulin in people with non-alcoholic liver cirrhosis and type 2 diabetes mellitus. ( 26803356 )
2016
10
A study on hematological spectrum in patients with alcoholic liver cirrhosis. ( 27727674 )
2016
11
Risk for alcoholic liver cirrhosis after an initial hospital contact with alcohol problems: A nationwide prospective cohort study. ( 27862159 )
2016
12
Confluent hepatic fibrosis in alcohol liver cirrhosis with elevated pivkaii value - usefulness of immunostaining for EZH2 and p16(INK4a) in differentiating it from cholangiolocellular carcinoma - Confluent hepatic fibrosis. ( 27418411 )
2016
13
A Single Nucleotide Polymorphism in the RASGRF2 Gene Is Associated with Alcoholic Liver Cirrhosis in Men. ( 27992614 )
2016
14
Proinflammatory Cytokines (IL-1I+, IL-6) and Hepatocyte Growth Factor in Patients with Alcoholic Liver Cirrhosis. ( 26448742 )
2015
15
Alcohol abuse and alcoholic liver cirrhosis leading to spontaneous muscle hematoma: an event fraught with danger. ( 25969676 )
2015
16
Alcohol dehydrogenase 1C (ADH1C) gene polymorphism and alcoholic liver cirrhosis risk: a meta analysis. ( 26379912 )
2015
17
Alcoholic Liver Cirrhosis and Significant Risk Factors for the Development of Alcohol-related Hepatocellular Carcinoma--Japan, 2012. ( 26946783 )
2015
18
A variant in the nuclear dot protein 52kDa gene increases the risk for spontaneous bacterial peritonitis in patients with alcoholic liver cirrhosis. ( 26493630 )
2015
19
Predictors of hepatorenal syndrome in alcoholic liver cirrhosis. ( 25820623 )
2015
20
Plasma osteopontin is a biomarker for the severity of alcoholic liver cirrhosis, not for hepatocellular carcinoma screening. ( 26122937 )
2015
21
Activity of MMP1 and MMP13 and Amino Acid Metabolism in Patients with Alcoholic Liver Cirrhosis. ( 25863779 )
2015
22
Aldehyde dehydrogenase 2 polymorphism influences development to hepatocellular carcinoma in East Asian alcoholic liver cirrhosis. ( 25778454 )
2015
23
Genetic polymorphism in alcohol dehydrogenase 2 (ADH2) gene and alcoholic liver cirrhosis risk. ( 26221330 )
2015
24
Alcohol drinking pattern and risk of alcoholic liver cirrhosis: A prospective cohort study. ( 25634330 )
2015
25
Flavobacterium ceti From Blood Samples of a Korean Patient With Alcoholic Liver Cirrhosis. ( 25932454 )
2015
26
Hypothyroidism Enhanced Portal Hypertension in a Patient with Alcoholic Liver Cirrhosis, Resulting in the Development of Ascites. ( 26370856 )
2015
27
Circulating Lipids Are Associated with Alcoholic Liver Cirrhosis and Represent Potential Biomarkers for Risk Assessment. ( 26107182 )
2015
28
Successful treatment of invasive gastric mucormycosis in a patient with alcoholic liver cirrhosis: A case report. ( 25009590 )
2014
29
Evidence of degraded BMD and geometry at the proximal femora in male patients with alcoholic liver cirrhosis. ( 25172381 )
2014
30
Interleukin 10 promoter haplotype is associated with alcoholic liver cirrhosis in Taiwanese patients. ( 24835349 )
2014
31
Lacosamide as add-on treatment of focal symptomatic epilepsy in a patient with alcoholic liver cirrhosis. ( 25667897 )
2014
32
Correlation between hepatic blood flow and liver function in alcoholic liver cirrhosis. ( 25493018 )
2014
33
Systematic review with meta-analysis: the I148M variant of patatin-like phospholipase domain-containing 3 gene (PNPLA3) is significantly associated with alcoholic liver cirrhosis. ( 25060292 )
2014
34
Vitamin D status, bone metabolism and bone mass in patients with alcoholic liver cirrhosis. ( 25318918 )
2014
35
Septic shock due to Aeromonas hydrophila bacteremia in a patient with alcoholic liver cirrhosis: a case report. ( 25464981 )
2014
36
Serum amyloid A and C-reactive protein positive nodule in alcoholic liver cirrhosis, hard to make definite diagnosis. ( 23607539 )
2013
37
Diagnostic significance of nitrates and nitrites and L-arginine, in development of hepatorenal syndrome in patients with end stage alcoholic liver cirrhosis. ( 23651488 )
2013
38
Evaluation of periodontal status in alcoholic liver cirrhosis patients: a comparative study. ( 23811642 )
2013
39
Portosystemic shunt via the superior mesenteric and right ovarian vein leading to small intestine bleeding in alcoholic liver cirrhosis. ( 23513021 )
2013
40
Alcoholic liver cirrhosis increases the risk of left ventricular diastolic dysfunction. ( 24362094 )
2013
41
Abnormalities in the serum phospholipids fatty acid profile in patients with alcoholic liver cirrhosis - a pilot study. ( 23874070 )
2013
42
An unusual cause of spontaneous bacterial peritonitis due to Campylobacter fetus with alcoholic liver cirrhosis. ( 23417384 )
2013
43
Serum albumin is present at higher levels in alcoholic liver cirrhosis as compared to HCV-related cirrhosis. ( 22969847 )
2012
44
Alcoholic chronic pancreatitis and alcoholic liver cirrhosis: differences in alcohol use habits and patterns in Indian subjects. ( 22481284 )
2012
45
Different patterns of decompensation in patients with alcoholic vs. non-alcoholic liver cirrhosis. ( 22530565 )
2012
46
Detection of alcohol consumption in patients with alcoholic liver cirrhosis during the evaluation process for liver transplantation. ( 22577089 )
2012
47
The effect of a single oral megadose of vitamin D provided as either ergocalciferol (Da88) or cholecalciferol (Da88) in alcoholic liver cirrhosis. ( 22027703 )
2012
48
Iliopsoas muscle hematoma secondary to alcoholic liver cirrhosis. ( 23185153 )
2012
49
Diagnostical significance of dimethylarginine in the development of hepatorenal syndrome in patients with alcoholic liver cirrhosis. ( 22924265 )
2012
50
New insight into the role of NT-proBNP in alcoholic liver cirrhosis as a noninvasive marker of esophageal varices. ( 22911531 )
2012

Variations for Alcoholic Liver Cirrhosis

Expression for Alcoholic Liver Cirrhosis

Search GEO for disease gene expression data for Alcoholic Liver Cirrhosis.

Pathways for Alcoholic Liver Cirrhosis

Pathways related to Alcoholic Liver Cirrhosis according to GeneCards Suite gene sharing:

(show all 17)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.88 ADH1B ADH1C ADH4 ALB ALDH2 CYP2A6
2
Show member pathways
12.86 ADH1B ADH1C ADH4 ALDH2 CYP2A6 CYP2E1
3
Show member pathways
12.45 ADH1B ADH1C ADH4 ALDH2
4
Show member pathways
12.02 ADH1B ALDH2 CYP2A6 CYP2E1
5
Show member pathways
11.81 ADH1B ADH1C ADH4 ALDH2 CYP2A6 CYP2E1
6
Show member pathways
11.67 ADH1B ADH1C ADH4 ALDH2
7
Show member pathways
11.6 CYP2A6 CYP2E1 GSTM1
8
Show member pathways
11.56 ADH1B ADH1C ADH4
9
Show member pathways
11.06 CYP2A6 CYP2E1 NAT2
10 10.99 CYP2A6 CYP2E1 GSTM1
11 10.86 CYP2A6 CYP2E1
12
Show member pathways
10.75 ADH1B ADH1C ADH4 ALDH2
13
Show member pathways
10.72 ADH1B ALDH2 CYP2E1
14 10.65 ADH1B ADH1C
15
Show member pathways
10.64 ADH1B ADH4 ALDH2
16
Show member pathways
10.37 ADH1B CYP2A6 CYP2E1
17 10.27 CYP2E1 GSTM1

GO Terms for Alcoholic Liver Cirrhosis

Cellular components related to Alcoholic Liver Cirrhosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum lumen GO:0005788 9.26 AHSG ALB F2 TF
2 blood microparticle GO:0072562 8.92 AHSG ALB F2 TF

Biological processes related to Alcoholic Liver Cirrhosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.56 AHSG ALB F2 TF
2 platelet degranulation GO:0002576 9.5 AHSG ALB TF
3 oxidation-reduction process GO:0055114 9.43 ADH1B ADH1C ADH4 ALDH2 CYP2A6 CYP2E1
4 drug metabolic process GO:0017144 9.4 CYP2A6 CYP2E1
5 epoxygenase P450 pathway GO:0019373 9.37 CYP2A6 CYP2E1
6 alcohol metabolic process GO:0006066 9.16 ADH4 ALDH2
7 ethanol oxidation GO:0006069 8.92 ADH1B ADH1C ADH4 ALDH2

Molecular functions related to Alcoholic Liver Cirrhosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 9.43 ADH1B ADH1C ADH4 ALDH2 CYP2A6 CYP2E1
2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 9.4 ADH4 ALDH2
3 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 9.37 CYP2A6 CYP2E1
4 retinol dehydrogenase activity GO:0004745 9.32 ADH1C ADH4
5 arachidonic acid epoxygenase activity GO:0008392 9.26 CYP2A6 CYP2E1
6 alcohol dehydrogenase (NAD) activity GO:0004022 9.16 ADH1C ADH4
7 alcohol dehydrogenase activity, zinc-dependent GO:0004024 8.8 ADH1B ADH1C ADH4

Sources for Alcoholic Liver Cirrhosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....