MCID: ALC011
MIFTS: 28

Alcoholic Neuropathy malady

Neuronal category

Summaries for Alcoholic Neuropathy

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Alcoholic polyneuropathy (A.K.A Alcohol leg) is a neurological disorder in which multiple peripheral... more...

MalaCards: Alcoholic Neuropathy, also known as alcohol-related polyneuropathy, is related to ulnar neuropathy and median neuropathy. An important gene associated with Alcoholic Neuropathy is ALDH2 (aldehyde dehydrogenase 2 family (mitochondrial)). The drugs hydroxocobalamin and thiamine and the compound histamine have been mentioned in the context of this disorder. Affiliated tissues include skin and liver.

Aliases & Classifications for Alcoholic Neuropathy

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 27ICD9CM, 57SNOMED-CT, 35MeSH, 40NCIt, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal


Aliases & Descriptions:

alcoholic neuropathy 8 10 45 61
alcohol-related polyneuropathy 8
alcoholic polyneuropathy 8


External Ids:

Disease Ontology8 DOID:14183
ICD9CM27 357.5
MeSH35 D020269
NCIt40 C26926
ICD1025 G62.1

Related Diseases for Alcoholic Neuropathy

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Alcoholic Neuropathy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1ulnar neuropathy10.0
2median neuropathy10.0
3n syndrome10.0
4guillain-barr� syndrome10.0
5gastritis10.0CXCL1
6adenoma10.0CXCL1

Graphical network of diseases related to Alcoholic Neuropathy:



Diseases related to alcoholic neuropathy

Clinical Features for Alcoholic Neuropathy

Drugs & Therapeutics for Alcoholic Neuropathy

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Alcoholic Neuropathy

Drug clinical trials:

Search ClinicalTrials for Alcoholic Neuropathy

Search NIH Clinical Center for Alcoholic Neuropathy

Search CenterWatch for Alcoholic Neuropathy

Inferred drug relations via UMLS61/NDF-RT41:

Genetic Tests for Alcoholic Neuropathy

Anatomical Context for Alcoholic Neuropathy

Sources:
33MalaCards
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MalaCards organs/tissues related to Alcoholic Neuropathy:

33
Skin, Liver

Animal Models for Alcoholic Neuropathy or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Alcoholic Neuropathy

Sources:
51PubMed
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Articles related to Alcoholic Neuropathy:

(show all 44)
idTitleAuthorsYear
1
Progression in idiopathic, diabetic, paraproteinemic, alcoholic, and B12 deficiency neuropathy. (24028193)
2013
2
Evaluation of ameliorative effect of quercetin in experimental model of alcoholic neuropathy in rats. (22349996)
2012
3
Therapeutic role of curcumin in prevention of biochemical and behavioral aberration induced by alcoholic neuropathy in laboratory animals. (22281447)
2012
4
Electrophysiological and behavioral changes by phosphodiesterase 4 inhibitor in a rat model of alcoholic neuropathy. (22993675)
2012
5
Alcoholic neuropathy: possible mechanisms and future treatment possibilities. (21988193)
2012
6
Amelioration of functional, biochemical and molecular deficits by epigallocatechin gallate in experimental model of alcoholic neuropathy. (20699198)
2011
7
Tocotrienol ameliorates behavioral and biochemical alterations in the rat model of alcoholic neuropathy. (19541419)
2009
8
Alcohol-induced stress in painful alcoholic neuropathy. (18093169)
2008
9
Alcoholic optic neuropathy: another complication of alcohol abuse. (18806243)
2008
10
Alcoholic neuropathy. (16969158)
2006
11
Resolution of alcoholic neuropathy following liver transplantation. (15558589)
2004
12
Alcoholic neuropathy is clinicopathologically distinct from thiamine-deficiency neuropathy. (12838517)
2003
13
Pathogenesis of alcoholic neuropathy. (12061083)
2002
14
Key role for the epsilon isoform of protein kinase C in painful alcoholic neuropathy in the rat. (11069970)
2000
15
Changes in sympathetic and parasympathetic function in alcoholic neuropathy. (9549310)
1998
16
Decreased muscle strength in patients with alcoholic liver cirrhosis in relation to nutritional status, alcohol abstinence, liver function, and neuropathy. (9581671)
1998
17
Mexiletine for painful alcoholic neuropathy. (7549147)
1995
18
Sympathetic dysfunction mediating cardiovascular regulation in alcoholic neuropathy. (7926889)
1994
19
Comparison of sympathetic sudomotor and skin responses in alcoholic neuropathy. (8455654)
1993
20
Acute or subacute alcoholic neuropathy mimicking Guillain-BarrAc syndrome. (2401897)
1990
21
The haematic thiamine level in the course of alcoholic neuropathy. (3032641)
1987
22
The primary role of the Erb's point--axilla segment in median and ulnar motor nerve conduction determinations in alcoholic neuropathy. (3011999)
1986
23
Peripheral neuropathy, cerebral atrophy, and intellectual impairment in chronic alcoholics. (6095578)
1984
24
Sympathetic vasoconstrictor nerve function in alcoholic neuropathy. (6540153)
1984
25
Alcoholic neuropathy associated with the eighth cranial nerve. (6867249)
1983
26
Alcoholic neuropathy and hepatopathy in mice. An experimental study. (6303042)
1983
27
Drinking habits and peripheral alcoholic neuropathy. (6278809)
1982
28
Alcohol, nutrition, and the nervous system. Alcoholic neuropathy. (6292675)
1982
29
Eighth nerve alcoholic neuropathy: a case report with light and electron microscopic findings. (7252342)
1981
30
Quantitative electrophysiological study of alcoholic neuropathy. (7420094)
1980
31
Animal models of alcoholic neuropathy: morphologic, electrophysiologic, and biochemical findings. (232540)
1979
32
Experimental alcoholic neuropathy in the rat: histological and electrophysiological study on the myoneural junctions and the peripheral nerves. (205081)
1978
33
Respective importance of different electrophysiological parameters in alcoholic neuropathy. (199711)
1977
34
Correlation of electrophysiological and quantitative histological findings in the sural nerve of man. Studies on alcoholic neuropathy. (72812)
1977
35
Alcoholic neuropathy. An electron-microscopic study. (169325)
1975
36
The sympathetic nervous system in alcoholic neuropathy. A clinical and pathological study. (171025)
1975
37
Electrophysiological evidence for a distal lesion in alcoholic neuropathy. (4343480)
1972
38
Pathogenesis of diabetic and alcoholic neuropathy. (5546239)
1971
39
Alcoholic neuropathy. (4328432)
1970
40
Alcoholic neuropathy. An electrophysiological and histological study. (4315536)
1970
41
Deterioration of esophageal peristalsis in patients with alcoholic neuropathy. (4298673)
1968
42
Alcoholic neuropathy. Its characteristic picture and variants viewed in the light of electromyography. (13766774)
1961
43
ALCOHOLIC neuropathy. (13050905)
1953
44
Alcoholic neuropathy and Laennec's cirrhosis. (15412051)
1950

Genetic Variations for Alcoholic Neuropathy

Expression for genes affiliated with Alcoholic Neuropathy

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Alcoholic Neuropathy

Search GEO for disease gene expression data for Alcoholic Neuropathy.

Pathways for genes affiliated with Alcoholic Neuropathy

Compounds for genes affiliated with Alcoholic Neuropathy

Sources:
45Novoseek, 29IUPHAR, 24HMDB
See all sources

Compounds related to Alcoholic Neuropathy according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1histamine45 29 2411.4ALDH2, CXCL1

GO Terms for genes affiliated with Alcoholic Neuropathy

Products for genes affiliated with Alcoholic Neuropathy

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Alcoholic Neuropathy

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet