MCID: ALC011
MIFTS: 29

Alcoholic Neuropathy malady

Category: Neuronal diseases

Aliases & Classifications for Alcoholic Neuropathy

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Aliases & Descriptions for Alcoholic Neuropathy:

Name: Alcoholic Neuropathy 11 13 48 37 66
Alcohol-Related Polyneuropathy 11
 
Alcoholic Polyneuropathy 11

Classifications:



External Ids:

Disease Ontology11 DOID:14183
ICD1028 G62.1
ICD9CM30 357.5
MeSH37 D020269
NCIt43 C26926

Summaries for Alcoholic Neuropathy

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Wikipedia:69 Alcoholic polyneuropathy (A.K.A alcohol leg) is a neurological disorder in which multiple peripheral... more...

MalaCards based summary: Alcoholic Neuropathy, also known as alcohol-related polyneuropathy, is related to neuropathy and polyneuropathy. An important gene associated with Alcoholic Neuropathy is MIA3 (MIA Family Member 3, ER Export Factor), and among its related pathways are Fatty acid metabolism and Cyclophosphamide Pathway, Pharmacodynamics. The drugs hydroxocobalamin and vitamin b 12 have been mentioned in the context of this disorder. Affiliated tissues include skin and liver.

Related Diseases for Alcoholic Neuropathy

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Diseases related to Alcoholic Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1neuropathy10.4
2polyneuropathy9.7
3esophagitis9.6
4narcolepsy 29.5ADH4, ALDH2
5amelogenesis imperfecta9.2ADH4, ALDH2
6hemangioma of intra-abdominal structure8.4ADH4, ALDH2, MIA3, SPTLC1
7frozen shoulder8.0ADH4, ALAD, ALDH2, MIA3, SPTLC1

Comorbidity relations with Alcoholic Neuropathy via Phenotypic Disease Network (PDN):


Deficiency AnemiaAlcohol Abuse
Alcoholic HepatitisAlcoholic Liver Cirrhosis
Protein-Energy MalnutritionAcute Cystitis

Graphical network of diseases related to Alcoholic Neuropathy:



Diseases related to alcoholic neuropathy

Symptoms for Alcoholic Neuropathy

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Drugs & Therapeutics for Alcoholic Neuropathy

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Drugs for Alcoholic Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Ethanol197164-17-5702
Synonyms:
(C6-C9)Alkyl alcohol
02483_FLUKA
02851_FLUKA
02853_FLUKA
02854_FLUKA
02855_FLUKA
02856_FLUKA
02856_SIAL
02857_FLUKA
02857_SIAL
02858_FLUKA
02858_SIAL
02860_FLUKA
02865_FLUKA
02865_SIAL
02870_FLUKA
02870_SIAL
02875_FLUKA
02877_FLUKA
02878_FLUKA
02882_FLUKA
02882_SIAL
02883_FLUKA
02884_FLUKA
02890_FLUKA
02890_SIAL
02891_FLUKA
02891_SIAL
1-Hydroxyethane
100C.NPA
121182-78-3
187380_ALDRICH
187380_SIAL
24102_RIEDEL
24102_SIAL
24103_RIEDEL
24103_SIAL
24105_RIEDEL
24105_SIAL
24106_RIEDEL
24106_SIAL
24194_RIEDEL
24194_SIAL
245119_ALDRICH
245119_SIAL
270741_ALDRICH
270741_SIAL
277649_ALDRICH
277649_SIAL
2858_SIGMA
29221_FLUKA
32205_RIEDEL
32205_SIAL
32221_RIEDEL
32221_SIAL
32294_RIEDEL
32294_SIAL
34870_SIAL
34963_RIEDEL
39278_FLUKA
40210_ALDRICH
40210_RIEDEL
41322_FLUKA
458600_ALDRICH
458600_SIAL
459828_ALDRICH
459828_SIAL
459836_ALDRICH
459836_SIAL
459844_SIAL
48075_SUPELCO
493511_SIAL
493538_ALDRICH
493538_SIAL
493546_ALDRICH
493546_SIAL
64-17-5
676829_SIAL
68475-56-9
71076-86-3
71329-38-9
8000-16-6
8024-45-1
AC1L19TW
AC1Q31MM
AHD 2000
AI3-01706
ALCOHOL 5% IN D5-W
Absolute Alcohol
Absolute Ethanol
Absolute alcohol
Absolute ethanol
Absolute ethyl alcohol
Aethanol
Aethanol [German]
Aethylalkohol
Alcare Hand Degermer
Alcohol
Alcohol (USP)
Alcohol (ethyl)
Alcohol Anhydrous
Alcohol [USP]
Alcohol anhydrous
Alcohol dehydrated
Alcohol denatured
Alcohol etílico
Alcohol, Absolute
Alcohol, Dehydrated
Alcohol, Diluted
Alcohol, Grain
Alcohol, anhydrous
Alcohol, dehydrated
Alcohol, denatured
Alcohol, diluted
Alcohol, ethyl
Alcohols
Alcohols, C1-3
Alcohols, C30
Alcohols, C6-9
Alcool Ethylique
Alcool Etilico
Alcool ethylique
Alcool etilico
Alcool éthylique
Algrain
Alkohol
Alkohol [German]
Alkoholu Etylowego
Alkoholu etylowego
Aminoethanol
Anhydrol
Anhydrol PM 4085
Anhydrous alcohol
Anhydrous ethanol
Beta-Aminoethanol
Beta-Aminoethyl Alcohol
Beta-Ethanolamine
Beta-Hydroxyethylamine
C00469
C2H5OH
C2H6O
CCRIS 945
CDA 19
CDA 19-200
CHEBI:16236
CHEMBL545
CID702
Caswell No. 426
Caswell No. 430
Colamine
Cologne Spirit
Cologne spirit
Cologne spirits
 
D000431
D00068
DB00898
Dehydrated Ethanol
Dehydrated alcohol
Dehydrated ethanol
Denatured Alcohol
Denatured Alcohol Cd-10
Denatured Alcohol Cd-5
Denatured Alcohol Cd-5a
Denatured Alcohol Sd-1
Denatured Alcohol Sd-13a
Denatured Alcohol Sd-17
Denatured Alcohol Sd-23a
Denatured Alcohol Sd-28
Denatured Alcohol Sd-30
Denatured Alcohol Sd-39b
Denatured Alcohol Sd-39c
Denatured Alcohol Sd-3a
Denatured Alcohol Sd-40m
Denatured Ethanol
Denatured alcohol
Denatured ethanol
Desinfektol EL
Diluted Alcohol
Distilled spirits
E2385_SIGMA
E7023_ALDRICH
E7023_SIAL
E7148_ALDRICH
E7148_SIAL
E7517_SIGMA
EINECS 200-578-6
EINECS 270-649-4
EOH
EOX
ETA
Envision Conditioner Pdd 9020
Esumiru WK 88
EtOH
Etanolo
Etanolo [Italian]
Ethanol (9CI)
Ethanol 200 Proof
Ethanol 200 proof
Ethanol Absolute
Ethanol Absolute Bp
Ethanol Anhydrous
Ethanol Extra Pure
Ethanol Vapor
Ethanol [JAN]
Ethanol solution
Ethanol, Silent Spirit
Ethanol, undenatured
Ethanolum anhydricum
Ethicap
Ethyl Alcohol
Ethyl Alcohol & Water, 10%
Ethyl Alcohol & Water, 20%
Ethyl Alcohol & Water, 30%
Ethyl Alcohol & Water, 40%
Ethyl Alcohol & Water, 5%
Ethyl Alcohol & Water, 50%
Ethyl Alcohol & Water, 60%
Ethyl Alcohol & Water, 70%
Ethyl Alcohol & Water, 80%
Ethyl Alcohol & Water, 95%
Ethyl Alcohol & Water, 96%
Ethyl Alcohol Anhydrous
Ethyl Alcohol, Anhydrous
Ethyl Alcohol, Denatured
Ethyl Hydrate
Ethyl Hydroxide
Ethyl alc
Ethyl alcohol
Ethyl alcohol anhydrous
Ethyl alcohol in alcoholic beverages
Ethyl alcohol usp
Ethyl hydrate
Ethyl hydroxide
Ethylalcohol
Ethylalcohol [Dutch]
Ethylol
Ethylolamine
Ethyloxy Group
Etylowy alkohol
FEMA No. 2419
FEMA Number 2419
Fermentation alcohol
Glycinol
Grain alcohol
HSDB 531
HSDB 82
HYDROXYETHYL GROUP
Hinetoless
Hydroxyethane
I14-12648
IMS 99
Infinity Pure
Jaysol
Jaysol S
LS-1539
LTBB002977
Lux
Methylated Spirit Mineralised
Methylated spirit
Methylcarbinol
MolPort-001-785-844
Molasses alcohol
NCGC00091458-01
NCI-C03134
NSC 85228
NSC85228
Oxydimethylene Group
Potato alcohol
Punctilious ethyl alcohol
Pyro
QMHAIh@
Reagent Alcohol
Ru-Tuss Expectorant
SDA 3A
SDA 40-2
SDM No. 37
SY Fresh M
Sekundasprit
Silent spirit
Spirit
Spirits of wine
Spiritus vini
Spirt
Synasol
Tecsol
Tecsol C
Thanol
Thiofaco M-50
UNII-3K9958V90M
USAF EK-1597
Undenatured Ethanol
WLN: Q2
absolute alcohol
alcohol
alcohol etilico
bmse000297
etanol
ethanol
ethyl alcohol
grain alcohol
nchem.651-comp3c
nchembio.552-comp10
nchembio.94-comp20
spiritus vini
Äthanol
Äthylalkohol
éthanol

Interventional clinical trials:

idNameStatusNCT IDPhase
1Somatic Disease Among Alcohol Abusers in an Out-day Patients' ClinicCompletedNCT01081197
2A Study of Phyllanthus Niruri and Sida Cordifolia in Diabetic Peripheral PolyneuropathyCompletedNCT02107469
3Cutaneous Denervation in Alcoholic NeuropathyRecruitingNCT00190073

Search NIH Clinical Center for Alcoholic Neuropathy

Inferred drug relations via UMLS66/NDF-RT44:


Cochrane evidence based reviews: alcoholic neuropathy

Genetic Tests for Alcoholic Neuropathy

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Anatomical Context for Alcoholic Neuropathy

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MalaCards organs/tissues related to Alcoholic Neuropathy:

34
Skin, Liver

Animal Models for Alcoholic Neuropathy or affiliated genes

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Publications for Alcoholic Neuropathy

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Articles related to Alcoholic Neuropathy:

(show all 42)
idTitleAuthorsYear
1
Erythrocyte transketolase activity in patients with diabetic and alcoholic neuropathies. (24114639)
2013
2
Evaluation of ameliorative effect of quercetin in experimental model of alcoholic neuropathy in rats. (22349996)
2012
3
Electrophysiological and behavioral changes by phosphodiesterase 4 inhibitor in a rat model of alcoholic neuropathy. (22993675)
2012
4
Alcoholic neuropathy: possible mechanisms and future treatment possibilities. (21988193)
2012
5
Therapeutic role of curcumin in prevention of biochemical and behavioral aberration induced by alcoholic neuropathy in laboratory animals. (22281447)
2012
6
Amelioration of functional, biochemical and molecular deficits by epigallocatechin gallate in experimental model of alcoholic neuropathy. (20699198)
2011
7
Tocotrienol ameliorates behavioral and biochemical alterations in the rat model of alcoholic neuropathy. (19541419)
2009
8
Alcohol-induced stress in painful alcoholic neuropathy. (18093169)
2008
9
Impact of cytokines on the pathomechanism of diabetic and alcoholic neuropathies. (17594598)
2007
10
Alcoholic neuropathy. (16969158)
2006
11
Resolution of alcoholic neuropathy following liver transplantation. (15558589)
2004
12
Alcoholic neuropathy is clinicopathologically distinct from thiamine-deficiency neuropathy. (12838517)
2003
13
Pathogenesis of alcoholic neuropathy. (12061083)
2002
14
Key role for the epsilon isoform of protein kinase C in painful alcoholic neuropathy in the rat. (11069970)
2000
15
Changes in sympathetic and parasympathetic function in alcoholic neuropathy. (9549310)
1998
16
Mexiletine for painful alcoholic neuropathy. (7549147)
1995
17
Sympathetic dysfunction mediating cardiovascular regulation in alcoholic neuropathy. (7926889)
1994
18
Comparison of sympathetic sudomotor and skin responses in alcoholic neuropathy. (8455654)
1993
19
Acute or subacute alcoholic neuropathy mimicking Guillain-BarrAc syndrome. (2401897)
1990
20
The haematic thiamine level in the course of alcoholic neuropathy. (3032641)
1987
21
The primary role of the Erb's point--axilla segment in median and ulnar motor nerve conduction determinations in alcoholic neuropathy. (3011999)
1986
22
Sympathetic vasoconstrictor nerve function in alcoholic neuropathy. (6540153)
1984
23
Alcoholic neuropathy associated with the eighth cranial nerve. (6867249)
1983
24
Alcoholic neuropathy and hepatopathy in mice. An experimental study. (6303042)
1983
25
Drinking habits and peripheral alcoholic neuropathy. (6278809)
1982
26
Alcohol, nutrition, and the nervous system. Alcoholic neuropathy. (6292675)
1982
27
Eighth nerve alcoholic neuropathy: a case report with light and electron microscopic findings. (7252342)
1981
28
Quantitative electrophysiological study of alcoholic neuropathy. (7420094)
1980
29
Animal models of alcoholic neuropathy: morphologic, electrophysiologic, and biochemical findings. (232540)
1979
30
Experimental alcoholic neuropathy in the rat: histological and electrophysiological study on the myoneural junctions and the peripheral nerves. (205081)
1978
31
Respective importance of different electrophysiological parameters in alcoholic neuropathy. (199711)
1977
32
Correlation of electrophysiological and quantitative histological findings in the sural nerve of man. Studies on alcoholic neuropathy. (72812)
1977
33
Alcoholic neuropathy. An electron-microscopic study. (169325)
1975
34
The sympathetic nervous system in alcoholic neuropathy. A clinical and pathological study. (171025)
1975
35
Electrophysiological evidence for a distal lesion in alcoholic neuropathy. (4343480)
1972
36
Pathogenesis of diabetic and alcoholic neuropathy. (5546239)
1971
37
Alcoholic neuropathy. (4328432)
1970
38
Alcoholic neuropathy. An electrophysiological and histological study. (4315536)
1970
39
Deterioration of esophageal peristalsis in patients with alcoholic neuropathy. (4298673)
1968
40
Alcoholic neuropathy. Its characteristic picture and variants viewed in the light of electromyography. (13766774)
1961
41
ALCOHOLIC neuropathy. (13050905)
1953
42
Alcoholic neuropathy and Laennec's cirrhosis. (15412051)
1950

Variations for Alcoholic Neuropathy

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Expression for genes affiliated with Alcoholic Neuropathy

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Search GEO for disease gene expression data for Alcoholic Neuropathy.

Pathways for genes affiliated with Alcoholic Neuropathy

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Pathways related to Alcoholic Neuropathy according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.1ADH4, ALDH2
2
Show member pathways
9.1ADH4, ALDH2
3
Show member pathways
9.1ADH4, ALDH2

GO Terms for genes affiliated with Alcoholic Neuropathy

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Biological processes related to Alcoholic Neuropathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ethanol oxidationGO:00060699.1ADH4, ALDH2
2alcohol metabolic processGO:00060669.1ADH4, ALDH2

Sources for Alcoholic Neuropathy

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet