MCID: ALC011
MIFTS: 34

Alcoholic Neuropathy malady

Neuronal diseases category
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Summaries for Alcoholic Neuropathy

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Wikipedia:65 Alcoholic polyneuropathy (A.K.A alcohol leg) is a neurological disorder in which multiple peripheral... more...

MalaCards based summary: Alcoholic Neuropathy, also known as alcohol-related polyneuropathy, is related to neuropathy and polyneuropathy. An important gene associated with Alcoholic Neuropathy is ALDH2 (aldehyde dehydrogenase 2 family (mitochondrial)), and among its related pathways is Metabolism. The drugs hydroxocobalamin and vitamin b 12 and the compound cholesterol have been mentioned in the context of this disorder. Affiliated tissues include liver and skin, and related mouse phenotype reproductive system.

Aliases & Classifications for Alcoholic Neuropathy

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 57SNOMED-CT, 34MeSH, 39NCIt, 27ICD9CM, 25ICD10
See all sources

Alcoholic Neuropathy, Aliases & Descriptions:

Name: Alcoholic Neuropathy 8 10 44 62
Alcohol-Related Polyneuropathy 8 62
 
Polyneuropathy, Alcoholic 62
Alcoholic Polyneuropathy 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


External Ids:

Disease Ontology8 DOID:14183
MeSH34 D020269
NCIt39 C26926
ICD9CM27 357.5
ICD1025 G62.1

Related Diseases for Alcoholic Neuropathy

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Diseases related to Alcoholic Neuropathy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1neuropathy10.8
2polyneuropathy10.1
3esophagitis10.0

Symptoms for Alcoholic Neuropathy

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Drugs & Therapeutics for Alcoholic Neuropathy

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Drug clinical trials:

Search ClinicalTrials for Alcoholic Neuropathy

Search NIH Clinical Center for Alcoholic Neuropathy

Inferred drug relations via UMLS62/NDF-RT40:

Genetic Tests for Alcoholic Neuropathy

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Anatomical Context for Alcoholic Neuropathy

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MalaCards organs/tissues related to Alcoholic Neuropathy:

32
Liver, Skin

Animal Models for Alcoholic Neuropathy or affiliated genes

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MGI Mouse Phenotypes related to Alcoholic Neuropathy:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053899.1ALDH2, SPTLC1

Publications for Alcoholic Neuropathy

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Articles related to Alcoholic Neuropathy:

(show all 42)
idTitleAuthorsYear
1
Erythrocyte transketolase activity in patients with diabetic and alcoholic neuropathies. (24114639)
2013
2
Evaluation of ameliorative effect of quercetin in experimental model of alcoholic neuropathy in rats. (22349996)
2012
3
Therapeutic role of curcumin in prevention of biochemical and behavioral aberration induced by alcoholic neuropathy in laboratory animals. (22281447)
2012
4
Electrophysiological and behavioral changes by phosphodiesterase 4 inhibitor in a rat model of alcoholic neuropathy. (22993675)
2012
5
Alcoholic neuropathy: possible mechanisms and future treatment possibilities. (21988193)
2012
6
Amelioration of functional, biochemical and molecular deficits by epigallocatechin gallate in experimental model of alcoholic neuropathy. (20699198)
2011
7
Tocotrienol ameliorates behavioral and biochemical alterations in the rat model of alcoholic neuropathy. (19541419)
2009
8
Alcohol-induced stress in painful alcoholic neuropathy. (18093169)
2008
9
Impact of cytokines on the pathomechanism of diabetic and alcoholic neuropathies. (17594598)
2007
10
Alcoholic neuropathy. (16969158)
2006
11
Resolution of alcoholic neuropathy following liver transplantation. (15558589)
2004
12
Alcoholic neuropathy is clinicopathologically distinct from thiamine-deficiency neuropathy. (12838517)
2003
13
Pathogenesis of alcoholic neuropathy. (12061083)
2002
14
Key role for the epsilon isoform of protein kinase C in painful alcoholic neuropathy in the rat. (11069970)
2000
15
Changes in sympathetic and parasympathetic function in alcoholic neuropathy. (9549310)
1998
16
Mexiletine for painful alcoholic neuropathy. (7549147)
1995
17
Sympathetic dysfunction mediating cardiovascular regulation in alcoholic neuropathy. (7926889)
1994
18
Comparison of sympathetic sudomotor and skin responses in alcoholic neuropathy. (8455654)
1993
19
Acute or subacute alcoholic neuropathy mimicking Guillain-BarrAc syndrome. (2401897)
1990
20
The haematic thiamine level in the course of alcoholic neuropathy. (3032641)
1987
21
The primary role of the Erb's point--axilla segment in median and ulnar motor nerve conduction determinations in alcoholic neuropathy. (3011999)
1986
22
Sympathetic vasoconstrictor nerve function in alcoholic neuropathy. (6540153)
1984
23
Alcoholic neuropathy associated with the eighth cranial nerve. (6867249)
1983
24
Alcoholic neuropathy and hepatopathy in mice. An experimental study. (6303042)
1983
25
Drinking habits and peripheral alcoholic neuropathy. (6278809)
1982
26
Alcohol, nutrition, and the nervous system. Alcoholic neuropathy. (6292675)
1982
27
Eighth nerve alcoholic neuropathy: a case report with light and electron microscopic findings. (7252342)
1981
28
Quantitative electrophysiological study of alcoholic neuropathy. (7420094)
1980
29
Animal models of alcoholic neuropathy: morphologic, electrophysiologic, and biochemical findings. (232540)
1979
30
Experimental alcoholic neuropathy in the rat: histological and electrophysiological study on the myoneural junctions and the peripheral nerves. (205081)
1978
31
Respective importance of different electrophysiological parameters in alcoholic neuropathy. (199711)
1977
32
Correlation of electrophysiological and quantitative histological findings in the sural nerve of man. Studies on alcoholic neuropathy. (72812)
1977
33
Alcoholic neuropathy. An electron-microscopic study. (169325)
1975
34
The sympathetic nervous system in alcoholic neuropathy. A clinical and pathological study. (171025)
1975
35
Electrophysiological evidence for a distal lesion in alcoholic neuropathy. (4343480)
1972
36
Pathogenesis of diabetic and alcoholic neuropathy. (5546239)
1971
37
Alcoholic neuropathy. (4328432)
1970
38
Alcoholic neuropathy. An electrophysiological and histological study. (4315536)
1970
39
Deterioration of esophageal peristalsis in patients with alcoholic neuropathy. (4298673)
1968
40
Alcoholic neuropathy. Its characteristic picture and variants viewed in the light of electromyography. (13766774)
1961
41
ALCOHOLIC neuropathy. (13050905)
1953
42
Alcoholic neuropathy and Laennec's cirrhosis. (15412051)
1950

Variations for Alcoholic Neuropathy

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Expression for genes affiliated with Alcoholic Neuropathy

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Expression patterns in normal tissues for genes affiliated with Alcoholic Neuropathy

Search GEO for disease gene expression data for Alcoholic Neuropathy.

Pathways for genes affiliated with Alcoholic Neuropathy

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Pathways related to Alcoholic Neuropathy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1ALDH2, SPTLC1

Compounds for genes affiliated with Alcoholic Neuropathy

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Sources:
44Novoseek, 28IUPHAR, 24HMDB, 11DrugBank
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Compounds related to Alcoholic Neuropathy according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1cholesterol44 28 24 1112.1ALDH2, SPTLC1

GO Terms for genes affiliated with Alcoholic Neuropathy

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Biological processes related to Alcoholic Neuropathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1small molecule metabolic processGO:0442819.1ALDH2, SPTLC1

Products for genes affiliated with Alcoholic Neuropathy

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  • Antibodies
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Sources for Alcoholic Neuropathy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet