MCID: ALC011
MIFTS: 31

Alcoholic Neuropathy malady

Neuronal diseases category

Summaries for Alcoholic Neuropathy

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63Wikipedia, 32MalaCards
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Wikipedia:63 Alcoholic polyneuropathy (A.K.A Alcohol leg) is a neurological disorder in which multiple peripheral... more...

MalaCards: Alcoholic Neuropathy, also known as alcohol-related polyneuropathy, is related to neuropathy and diabetic neuropathy. An important gene associated with Alcoholic Neuropathy is ALDH2 (aldehyde dehydrogenase 2 family (mitochondrial)). The drugs hydroxocobalamin and thiamine and the compound histamine have been mentioned in the context of this disorder. Affiliated tissues include liver and skin.

Aliases & Classifications for Alcoholic Neuropathy

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 27ICD9CM, 56SNOMED-CT, 34MeSH, 39NCIt, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

alcoholic neuropathy 8 10 44 60
alcohol-related polyneuropathy 8
alcoholic polyneuropathy 8


External Ids:

Disease Ontology8 DOID:14183
ICD9CM27 357.5
MeSH34 D020269
NCIt39 C26926
ICD1025 G62.1

Related Diseases for Alcoholic Neuropathy

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17GeneCards, 18GeneDecks
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Diseases related to Alcoholic Neuropathy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1neuropathy10.8
2diabetic neuropathy10.1
3peripheral neuropathy10.1
4polyneuropathy10.0
5gastritis10.0CXCL1
6adenoma10.0CXCL1
7ulnar neuropathy10.0
8median neuropathy10.0
9esophagitis10.0

Graphical network of diseases related to Alcoholic Neuropathy:



Diseases related to alcoholic neuropathy

Clinical Features for Alcoholic Neuropathy

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Drugs & Therapeutics for Alcoholic Neuropathy

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Alcoholic Neuropathy

Drug clinical trials:

Search ClinicalTrials for Alcoholic Neuropathy

Search NIH Clinical Center for Alcoholic Neuropathy

Search CenterWatch for Alcoholic Neuropathy

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Alcoholic Neuropathy

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Anatomical Context for Alcoholic Neuropathy

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32MalaCards
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MalaCards organs/tissues related to Alcoholic Neuropathy:

32
Liver, Skin

Animal Models for Alcoholic Neuropathy or affiliated genes

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Publications for Alcoholic Neuropathy

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50PubMed
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Articles related to Alcoholic Neuropathy:

(show top 50)    (show all 60)
idTitleAuthorsYear
1
Independent contributions of alcohol and stress axis hormones to painful peripheral neuropathy. (23128028)
2013
2
Progression in idiopathic, diabetic, paraproteinemic, alcoholic, and B12 deficiency neuropathy. (24028193)
2013
3
Evaluation of ameliorative effect of quercetin in experimental model of alcoholic neuropathy in rats. (22349996)
2012
4
Experimental alcohol-related peripheral neuropathy: role of insulin/IGF resistance. (23016131)
2012
5
Severe acute bilateral alcohol-induced toxic optic neuropathy--case report. (23373403)
2012
6
Therapeutic role of curcumin in prevention of biochemical and behavioral aberration induced by alcoholic neuropathy in laboratory animals. (22281447)
2012
7
Electrophysiological and behavioral changes by phosphodiesterase 4 inhibitor in a rat model of alcoholic neuropathy. (22993675)
2012
8
Hooch blindness: a community study report on a few indoor patients of toxic optic neuropathy following consumption of adulterated alcohol in West Bengal. (22344014)
2012
9
Alcoholic neuropathy: possible mechanisms and future treatment possibilities. (21988193)
2012
10
Mutations for Leber hereditary optic neuropathy in patients with alcohol and tobacco optic neuropathy. (22194643)
2011
11
Amelioration of functional, biochemical and molecular deficits by epigallocatechin gallate in experimental model of alcoholic neuropathy. (20699198)
2011
12
Muscle pain in models of chemotherapy-induced and alcohol-induced peripheral neuropathy. (21786301)
2011
13
Acute motor axonal neuropathy: a severe complication of alcohol abuse. (21037141)
2010
14
Evaluation of retinal nerve fiber layer thickness measurements using optical coherence tomography in patients with tobacco-alcohol-induced toxic optic neuropathy. (20952853)
2010
15
Evaluation of retinal nerve fiber layer thickness measurements using optical coherence tomography in patients with tobacco-alcohol-induced toxic optic neuropathy. (20195038)
2010
16
Tocotrienol ameliorates behavioral and biochemical alterations in the rat model of alcoholic neuropathy. (19541419)
2009
17
Alcohol-induced stress in painful alcoholic neuropathy. (18093169)
2008
18
Alcoholic optic neuropathy: another complication of alcohol abuse. (18806243)
2008
19
Impact of cytokines on the pathomechanism of diabetic and alcoholic neuropathies. (17594598)
2007
20
Resolution of alcoholic neuropathy following liver transplantation. (15558589)
2004
21
Pathogenesis of alcoholic neuropathy. (12061083)
2002
22
Key role for the epsilon isoform of protein kinase C in painful alcoholic neuropathy in the rat. (11069970)
2000
23
Changes in sympathetic and parasympathetic function in alcoholic neuropathy. (9549310)
1998
24
Alcoholism, peripheral neuropathy (PNP) and cardiovascular autonomic neuropathy (CAN). (9879694)
1998
25
Decreased muscle strength in patients with alcoholic liver cirrhosis in relation to nutritional status, alcohol abstinence, liver function, and neuropathy. (9581671)
1998
26
Genotypes of aldehyde dehydrogenase and alcohol dehydrogenase polymorphisms in patients with Leber's hereditary optic neuropathy. (9183998)
1997
27
Mexiletine for painful alcoholic neuropathy. (7549147)
1995
28
Sympathetic dysfunction mediating cardiovascular regulation in alcoholic neuropathy. (7926889)
1994
29
Comparison of sympathetic sudomotor and skin responses in alcoholic neuropathy. (8455654)
1993
30
Acute or subacute alcoholic neuropathy mimicking Guillain-BarrAc syndrome. (2401897)
1990
31
The haematic thiamine level in the course of alcoholic neuropathy. (3032641)
1987
32
The primary role of the Erb's point--axilla segment in median and ulnar motor nerve conduction determinations in alcoholic neuropathy. (3011999)
1986
33
Sympathetic vasoconstrictor nerve function in alcoholic neuropathy. (6540153)
1984
34
Alcoholic neuropathy associated with the eighth cranial nerve. (6867249)
1983
35
Drinking habits and peripheral alcoholic neuropathy. (6278809)
1982
36
Alcohol, nutrition, and the nervous system. Alcoholic neuropathy. (6292675)
1982
37
Eighth nerve alcoholic neuropathy: a case report with light and electron microscopic findings. (7252342)
1981
38
Quantitative electrophysiological study of alcoholic neuropathy. (7420094)
1980
39
Animal models of alcoholic neuropathy: morphologic, electrophysiologic, and biochemical findings. (232540)
1979
40
Experimental alcoholic neuropathy in the rat: histological and electrophysiological study on the myoneural junctions and the peripheral nerves. (205081)
1978
41
Respective importance of different electrophysiological parameters in alcoholic neuropathy. (199711)
1977
42
Alcoholic neuropathy. An electron-microscopic study. (169325)
1975
43
The sympathetic nervous system in alcoholic neuropathy. A clinical and pathological study. (171025)
1975
44
Electrophysiological evidence for a distal lesion in alcoholic neuropathy. (4343480)
1972
45
Pathogenesis of diabetic and alcoholic neuropathy. (5546239)
1971
46
Alcoholic neuropathy. (4328432)
1970
47
Deterioration of esophageal peristalsis in patients with alcoholic neuropathy. (4298673)
1968
48
Alcoholic neuropathy. Its characteristic picture and variants viewed in the light of electromyography. (13766774)
1961
49
ALCOHOLIC neuropathy. (13050905)
1953
50
Alcoholic neuropathy and Laennec's cirrhosis. (15412051)
1950

Genetic Variations for Alcoholic Neuropathy

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Expression for genes affiliated with Alcoholic Neuropathy

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Alcoholic Neuropathy

Search GEO for disease gene expression data for Alcoholic Neuropathy.

Pathways for genes affiliated with Alcoholic Neuropathy

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Compounds for genes affiliated with Alcoholic Neuropathy

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44Novoseek, 28IUPHAR, 24HMDB
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Compounds related to Alcoholic Neuropathy according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1histamine44 28 2411.4ALDH2, CXCL1

GO Terms for genes affiliated with Alcoholic Neuropathy

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Products for genes affiliated with Alcoholic Neuropathy

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Alcoholic Neuropathy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet