MCID: ALC011
MIFTS: 32

Alcoholic Neuropathy malady

Neuronal diseases category

Aliases & Classifications for Alcoholic Neuropathy

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Sources:
10Disease Ontology, 47Novoseek, 12DISEASES, 65UMLS, 36MeSH, 59SNOMED-CT, 42NCIt, 29ICD9CM, 27ICD10
See all sources

Aliases & Descriptions for Alcoholic Neuropathy:

Name: Alcoholic Neuropathy 10 47 12 65 36
Alcohol-Related Polyneuropathy 10
 
Alcoholic Polyneuropathy 10


Classifications:



External Ids:

Disease Ontology10 DOID:14183
MeSH36 D020269
NCIt42 C26926
ICD9CM29 357.5
ICD1027 G62.1

Summaries for Alcoholic Neuropathy

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Wikipedia:68 Alcoholic polyneuropathy (A.K.A alcohol leg) is a neurological disorder in which multiple peripheral... more...

MalaCards based summary: Alcoholic Neuropathy, also known as alcohol-related polyneuropathy, is related to alcohol dependence and neuropathy. An important gene associated with Alcoholic Neuropathy is ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial)), and among its related pathways are Fatty acid metabolism and Cyclophosphamide Pathway, Pharmacodynamics. The drugs hydroxocobalamin and mecobalamin have been mentioned in the context of this disorder. Affiliated tissues include skin and liver.

Related Diseases for Alcoholic Neuropathy

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Graphical network of the top 20 diseases related to Alcoholic Neuropathy:



Diseases related to alcoholic neuropathy

Symptoms for Alcoholic Neuropathy

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Drugs & Therapeutics for Alcoholic Neuropathy

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Drugs for Alcoholic Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1

Interventional clinical trials:

idNameStatusNCT IDPhase
1Somatic Disease Among Alcohol Abusers in an Out-day Patients' ClinicCompletedNCT01081197
2A Study of Phyllanthus Niruri and Sida Cordifolia in Diabetic Peripheral PolyneuropathyCompletedNCT02107469
3Cutaneous Denervation in Alcoholic NeuropathyRecruitingNCT00190073

Search NIH Clinical Center for Alcoholic Neuropathy

Inferred drug relations via UMLS65/NDF-RT43:


Cochrane evidence based reviews: Alcoholic Neuropathy

Genetic Tests for Alcoholic Neuropathy

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Anatomical Context for Alcoholic Neuropathy

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MalaCards organs/tissues related to Alcoholic Neuropathy:

33
Skin, Liver

Animal Models for Alcoholic Neuropathy or affiliated genes

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Publications for Alcoholic Neuropathy

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Articles related to Alcoholic Neuropathy:

(show all 41)
idTitleAuthorsYear
1
Erythrocyte transketolase activity in patients with diabetic and alcoholic neuropathies. (24114639)
2013
2
Evaluation of ameliorative effect of quercetin in experimental model of alcoholic neuropathy in rats. (22349996)
2012
3
Therapeutic role of curcumin in prevention of biochemical and behavioral aberration induced by alcoholic neuropathy in laboratory animals. (22281447)
2012
4
Electrophysiological and behavioral changes by phosphodiesterase 4 inhibitor in a rat model of alcoholic neuropathy. (22993675)
2012
5
Alcoholic neuropathy: possible mechanisms and future treatment possibilities. (21988193)
2012
6
Amelioration of functional, biochemical and molecular deficits by epigallocatechin gallate in experimental model of alcoholic neuropathy. (20699198)
2011
7
Tocotrienol ameliorates behavioral and biochemical alterations in the rat model of alcoholic neuropathy. (19541419)
2009
8
Alcohol-induced stress in painful alcoholic neuropathy. (18093169)
2008
9
Impact of cytokines on the pathomechanism of diabetic and alcoholic neuropathies. (17594598)
2007
10
Alcoholic neuropathy. (16969158)
2006
11
Resolution of alcoholic neuropathy following liver transplantation. (15558589)
2004
12
Alcoholic neuropathy is clinicopathologically distinct from thiamine-deficiency neuropathy. (12838517)
2003
13
Pathogenesis of alcoholic neuropathy. (12061083)
2002
14
Key role for the epsilon isoform of protein kinase C in painful alcoholic neuropathy in the rat. (11069970)
2000
15
Changes in sympathetic and parasympathetic function in alcoholic neuropathy. (9549310)
1998
16
Mexiletine for painful alcoholic neuropathy. (7549147)
1995
17
Sympathetic dysfunction mediating cardiovascular regulation in alcoholic neuropathy. (7926889)
1994
18
Comparison of sympathetic sudomotor and skin responses in alcoholic neuropathy. (8455654)
1993
19
Acute or subacute alcoholic neuropathy mimicking Guillain-BarrAc syndrome. (2401897)
1990
20
The haematic thiamine level in the course of alcoholic neuropathy. (3032641)
1987
21
The primary role of the Erb's point--axilla segment in median and ulnar motor nerve conduction determinations in alcoholic neuropathy. (3011999)
1986
22
Sympathetic vasoconstrictor nerve function in alcoholic neuropathy. (6540153)
1984
23
Alcoholic neuropathy associated with the eighth cranial nerve. (6867249)
1983
24
Alcoholic neuropathy and hepatopathy in mice. An experimental study. (6303042)
1983
25
Drinking habits and peripheral alcoholic neuropathy. (6278809)
1982
26
Alcohol, nutrition, and the nervous system. Alcoholic neuropathy. (6292675)
1982
27
Eighth nerve alcoholic neuropathy: a case report with light and electron microscopic findings. (7252342)
1981
28
Animal models of alcoholic neuropathy: morphologic, electrophysiologic, and biochemical findings. (232540)
1979
29
Experimental alcoholic neuropathy in the rat: histological and electrophysiological study on the myoneural junctions and the peripheral nerves. (205081)
1978
30
Respective importance of different electrophysiological parameters in alcoholic neuropathy. (199711)
1977
31
Correlation of electrophysiological and quantitative histological findings in the sural nerve of man. Studies on alcoholic neuropathy. (72812)
1977
32
Alcoholic neuropathy. An electron-microscopic study. (169325)
1975
33
The sympathetic nervous system in alcoholic neuropathy. A clinical and pathological study. (171025)
1975
34
Electrophysiological evidence for a distal lesion in alcoholic neuropathy. (4343480)
1972
35
Pathogenesis of diabetic and alcoholic neuropathy. (5546239)
1971
36
Alcoholic neuropathy. (4328432)
1970
37
Alcoholic neuropathy. An electrophysiological and histological study. (4315536)
1970
38
Deterioration of esophageal peristalsis in patients with alcoholic neuropathy. (4298673)
1968
39
Alcoholic neuropathy. Its characteristic picture and variants viewed in the light of electromyography. (13766774)
1961
40
ALCOHOLIC neuropathy. (13050905)
1953
41
Alcoholic neuropathy and Laennec's cirrhosis. (15412051)
1950

Variations for Alcoholic Neuropathy

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Expression for genes affiliated with Alcoholic Neuropathy

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Search GEO for disease gene expression data for Alcoholic Neuropathy.

Pathways for genes affiliated with Alcoholic Neuropathy

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GO Terms for genes affiliated with Alcoholic Neuropathy

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Biological processes related to Alcoholic Neuropathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ethanol oxidationGO:00060699.6ADH4, ALDH2
2alcohol metabolic processGO:00060669.2ADH4, ALDH2
3xenobiotic metabolic processGO:00068058.9ADH4, ALDH2

Molecular functions related to Alcoholic Neuropathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptorGO:00166209.2ADH4, ALDH2

Sources for Alcoholic Neuropathy

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet