MCID: ALC005
MIFTS: 39

Alcoholic Pancreatitis malady

Endocrine diseases category

Summaries for Alcoholic Pancreatitis

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34MalaCards
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MalaCards: Alcoholic Pancreatitis, also known as pancreatitis, alcoholic, is related to pancreatitis and tropical calcific pancreatitis. An important gene associated with Alcoholic Pancreatitis is SPINK1 (serine peptidase inhibitor, Kazal type 1), and among its related pathways are Selected targets of CREB1 and Peptide ligand-binding receptors. The compounds benzodiazepine and enterostatin have been mentioned in the context of this disorder. Affiliated tissues include pancreas, liver and testes, and related mouse phenotype homeostasis/metabolism.

Aliases & Classifications for Alcoholic Pancreatitis

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Sources:
9Disease Ontology, 11DISEASES, 46Novoseek, 63UMLS, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Endocrine diseases


Aliases & Descriptions:

alcoholic pancreatitis 9 11
pancreatitis, alcoholic 63
pancreatitis alcoholic 46


External Ids:

Disease Ontology9 DOID:4988
MeSH36 D019512

Related Diseases for Alcoholic Pancreatitis

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Alcoholic Pancreatitis:



Diseases related to alcoholic pancreatitis

Symptoms for Alcoholic Pancreatitis

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Drugs & Therapeutics for Alcoholic Pancreatitis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Alcoholic Pancreatitis

Drug clinical trials:

Search ClinicalTrials for Alcoholic Pancreatitis

Search NIH Clinical Center for Alcoholic Pancreatitis

Search CenterWatch for Alcoholic Pancreatitis

Genetic Tests for Alcoholic Pancreatitis

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Anatomical Context for Alcoholic Pancreatitis

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34MalaCards
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MalaCards organs/tissues related to Alcoholic Pancreatitis:

34
Pancreas, Liver, Testes, Skin, Spinal cord

Animal Models for Alcoholic Pancreatitis or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Alcoholic Pancreatitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.7CCK, IAPP, DBI, NQO2, SPINK1

Publications for Alcoholic Pancreatitis

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53PubMed
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Articles related to Alcoholic Pancreatitis:

(show top 50)    (show all 239)
idTitleAuthorsYear
1
Is alcoholic pancreatitis associated with enteroviral infection? (23840120)
2013
2
Goal-related outcome after acute alcohol-pancreatitis -- a two-year follow-up study. (24018221)
2013
3
Serum proinflammatory cytokine levels and white blood cell differential count in patients with different degrees of severity of acute alcoholic pancreatitis. (22763297)
2012
4
Fatty acid composition of plasma lipid classes in chronic alcoholic pancreatitis. (20980776)
2010
5
Mechanisms of alcoholic pancreatitis. (21091991)
2010
6
Alcoholic pancreatitis: lessons from the liver. (20238397)
2010
7
Association analyses of genetic polymorphisms of GSTM1, GSTT1, NQO1, NAT2, LPL, PRSS1, PSTI, and CFTR with chronic alcoholic pancreatitis in Japan. (18986377)
2010
8
Ascites with Strongyloides stercoralis in a patient with acute alcoholic pancreatitis and liver cirrhosis. (19795035)
2009
9
A novel SPINK1 gene mutation, c.206C>T, in a Thai patient with chronic alcoholic pancreatitis. (18182741)
2008
10
Individual susceptibility to alcoholic pancreatitis. (18336667)
2008
11
Pancreatic stellate cells and chronic alcoholic pancreatitis. (17356252)
2007
12
Activated perilobular, not periacinar, pancreatic stellate cells contribute to fibrogenesis in chronic alcoholic pancreatitis. (17199738)
2007
13
Cystic dystrophy of the duodenal wall associated with chronic alcoholic pancreatitis. Clinical features, diagnostic procedures and therapeutic management in a retrospective multicenter series of 23 patients. (16733382)
2006
14
Duodenal diazepam-binding protein expression and plasma cholecystokinin after alcoholic pancreatitis. (17101560)
2006
15
Endoscopic transgastric debridement and drainage for splenic necrosis following an acute episode in chronic alcoholic pancreatitis. (16802272)
2006
16
Purtscher's like retinopathy as the presenting feature of acute alcoholic pancreatitis. (15803177)
2006
17
Is it long-term continuous drinking or the post-drinking withdrawal period that triggers the first acute alcoholic pancreatitis? (16265780)
2005
18
Alcoholic pancreatitis. (15528016)
2004
19
Does acute alcoholic pancreatitis precede the chronic form or is the opposite true? A histological study. (15128075)
2004
20
Elevated fasting plasma level of islet amyloid polypeptide (IAPP) in chronic alcoholic pancreatitis (CAP). (12630035)
2003
21
Short note about a symposium on alcoholic pancreatitis. (12649569)
2003
22
Animal models in alcoholic pancreatitis--what can we learn? (12138724)
2002
23
Usefulness of carbohydrate-deficient transferrin and trypsin activity in the diagnosis of acute alcoholic pancreatitis. (11419828)
2001
24
Neurological damage and duodenopancreatic reflux in the pathogenesis of alcoholic pancreatitis. (10722028)
2000
25
Screening for mutations of the cationic trypsinogen gene: are they of relevance in chronic alcoholic pancreatitis? (10026330)
1999
26
Alcoholic pancreatitis and polymorphisms of the variable length polythymidine tract in the cystic fibrosis gene. (10195826)
1999
27
FAEE injury in rats: relevant to alcoholic pancreatitis? (9428243)
1998
28
Acute alcoholic pancreatitis does not lead to complete recovery. (9088129)
1996
29
The relationship between drinking status and serial changes of pancreatographic findings in patients with suspected early chronic alcoholic pancreatitis. (8829191)
1996
30
Enteral nutritional support in acute alcoholic pancreatitis. (8598429)
1995
31
Trypsin activity. A new marker of acute alcoholic pancreatitis. (7527752)
1994
32
Pancreaticoduodenectomy for recurrent alcoholic pancreatitis associated with microabscesses. (8096346)
1993
33
Factors predictive of liver histopathological appearance in chronic alcoholic pancreatitis with common bile duct stenosis and increased serum alkaline phosphatase. (8225211)
1993
34
Variations of the pancreatic ducts as a cause of chronic alcoholic pancreatitis; ansa pancreatica. (1590328)
1992
35
The role of acetaldehyde in the pathogenesis of acute alcoholic pancreatitis. (1720611)
1991
36
Aberrant pancreas is not susceptible to alcoholic pancreatitis. (2051062)
1991
37
Histopathologic and immunohistochemical studies on alcoholic pancreatitis and chronic obstructive pancreatitis: special emphasis on ductal obstruction and genesis of pancreatitis. (2178399)
1990
38
On the pathogenesis of chronic alcoholic pancreatitis from the viewpoint of experimental results in rats. (3681035)
1987
39
Diet and drinking habits in alcoholic pancreatitis. (3699570)
1986
40
Blood group lewis phenotype on erythrocytes and in saliva in alcoholic pancreatitis and chronic liver disease. (6430969)
1984
41
Physiopathogenic basis of alcoholic pancreatitis: the effects of elevated cholinergic tone and increased "pancreon" ecbolic response to CCK-PZ. (6361529)
1983
42
Gastric secretion, gastroduodenal histological changes, and serum gastrin in chronic alcoholic pancreatitis. (7072677)
1982
43
Sixteen years follow-up of a patient with alcoholic pancreatitis: serial findings of morphology and function on the pancreas and the liver. (7141202)
1982
44
Peritoneal dialysis in the treatment of acute alcoholic pancreatitis. (7376052)
1980
45
HLA antigens in chronic alcoholic pancreatitis. (442066)
1979
46
Predictive value of biochemical indexes in acute alcoholic pancreatitis. (617496)
1977
47
Cyclic AMP as a determinant of the course of acute alcoholic pancreatitis. (175517)
1975
48
Chronic calcifying pancreatitis--chronic alcoholic pancreatitis. (4595185)
1974
49
Experimental acute alcoholic pancreatitis. (5264055)
1970
50
The clinical varieties of alcoholic pancreatitis in the South Western Cape--a review of 206 cases. (5854981)
1965

Variations for Alcoholic Pancreatitis

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Expression for genes affiliated with Alcoholic Pancreatitis

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Alcoholic Pancreatitis

Search GEO for disease gene expression data for Alcoholic Pancreatitis.

Pathways for genes affiliated with Alcoholic Pancreatitis

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51PathCards, 13EMD Millipore, 56Reactome, 39NCBI BioSystems Database, 31KEGG
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Compounds for genes affiliated with Alcoholic Pancreatitis

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46Novoseek, 30IUPHAR, 12DrugBank, 52PharmGKB, 3BitterDB, 25HMDB, 62Tocris Bioscience
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Compounds related to Alcoholic Pancreatitis according to GeneCards/GeneDecks:

(show all 16)
idCompoundScoreTop Affiliating Genes
1benzodiazepine469.4CCK, DBI
2enterostatin469.4CCK, IAPP
3rimonabant46 30 1211.4IAPP, CCK
4pramlintide46 1210.4CCK, IAPP
5incretin469.4IAPP, CCK
6amphetamine46 52 1211.4CCK, IAPP
7c-peptide469.3CCK, IAPP
8opiate469.3IAPP, CCK
9amide469.3CCK, IAPP
10acetaminophen46 3 52 25 1213.2CCK, IAPP
11ibmx46 62 3011.1CCK, IAPP
12trypsinogen468.9CCK, PRSS1, SPINK1
13cocaine46 129.8CCK, IAPP
14cholesterol46 30 25 1211.7CCK, IAPP, DBI
15arginine468.5PRSS1, IAPP, CCK
16calcium46 52 25 1211.0CCK, IAPP, PRSS1, SPINK1

GO Terms for genes affiliated with Alcoholic Pancreatitis

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17Gene Ontology
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Cellular components related to Alcoholic Pancreatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.1CCK, IAPP, PRSS1, SPINK1

Biological processes related to Alcoholic Pancreatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1eating behaviorGO:0427559.1CCK, IAPP

Molecular functions related to Alcoholic Pancreatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:0051799.1CCK, IAPP

Products for genes affiliated with Alcoholic Pancreatitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Alcoholic Pancreatitis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet