MCID: ALC003
MIFTS: 35

Alcoholic Psychosis

Categories: Mental diseases

Aliases & Classifications for Alcoholic Psychosis

MalaCards integrated aliases for Alcoholic Psychosis:

Name: Alcoholic Psychosis 12 52 14
Psychoses, Alcoholic 42 69
Alcoholic Psychoses 12

Classifications:



External Ids:

Disease Ontology 12 DOID:252
ICD9CM 35 291.9
MeSH 42 D011604
UMLS 69 C0033936

Summaries for Alcoholic Psychosis

MalaCards based summary : Alcoholic Psychosis, also known as psychoses, alcoholic, is related to conjunctival degeneration and anodontia. An important gene associated with Alcoholic Psychosis is SLC6A4 (Solute Carrier Family 6 Member 4), and among its related pathways/superpathways are Circadian rythm related genes and Monoamine Transport. The drugs Acamprosate and Ethanol have been mentioned in the context of this disorder. Affiliated tissues include brain, liver and testes.

Related Diseases for Alcoholic Psychosis

Diseases related to Alcoholic Psychosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 58)
id Related Disease Score Top Affiliating Genes
1 conjunctival degeneration 10.6 HTR2A SLC6A4
2 anodontia 10.6 SLC6A3 SLC6A4
3 neurogenic bladder 10.6 HTR2A SLC6A4
4 tinea pedis 10.6 SLC6A3 SLC6A4
5 intrahepatic gall duct cancer 10.5 HTR2A SLC6A4
6 ornithosis 10.5 DRD2 SLC6A4
7 obsessive-compulsive personality disorder 10.5 HTR2A SLC6A4
8 anosognosia 10.5 DRD2 SLC6A4
9 teebi kaurah syndrome 10.5 DRD2 HTR2A
10 acquired aneurysmal subarachnoid hemorrhage 10.5 HTR2A SLC6A4
11 eosinophilia-myalgia syndrome 10.5 DRD2 SLC6A3
12 allergic hypersensitivity disease 10.4 DRD2 HTR2A
13 tubular variant testicular seminoma 10.4 NPS SLC6A3
14 vascular cancer 10.4 DRD2 HTR2A
15 simpson-golabi-behmel syndrome 10.4 DRD2 SLC6A3
16 pelvic inflammatory disease 10.4 DRD2 SLC6A4
17 suppurative periapical periodontitis 10.4 DRD2 SLC6A4
18 primary angle-closure glaucoma 10.4 HTR2A SLC6A4
19 hepatic angiomyolipoma 10.3 HTR2A SLC6A3 SLC6A4
20 keratosis 10.3 HTR2A SLC6A4
21 hemorrhagic cystitis 10.3 DRD2 SLC6A3 SLC6A4
22 tongue disease 10.3 DRD2 SLC6A3 SLC6A4
23 hyperthyroxinemia 10.3 DRD2 HTR2A SLC6A4
24 bladder hepatoid adenocarcinoma 10.3 DRD2 SLC6A3 SLC6A4
25 pompholyx 10.3 DRD2 HTR2A SLC6A4
26 acute female pelvic peritonitis 10.3 DRD2 SLC6A3 SLC6A4
27 carotid stenosis 10.3 DRD2 SLC6A3 SLC6A4
28 pauci-immune glomerulonephritis with anca 10.3 DRD2 HTR2A SLC6A4
29 colon mucinous adenocarcinoma 10.3 DRD2 SLC6A3 SLC6A4
30 perry syndrome 10.3 NPS SLC6A3
31 spinal meningioma 10.3 DRD2 HTR2A
32 perinatal necrotizing enterocolitis 10.3 DRD2 SLC6A3 SLC6A4
33 contact dermatitis 10.3 DRD2 HTR2A SLC6A3
34 postencephalitic parkinson disease 10.3 DRD2 HTR2A SLC6A4
35 heroin dependence 10.3 DRD2 SLC6A3 SLC6A4
36 hereditary multiple exostoses 10.2 DRD2 HTR2A SLC6A4
37 bladder flat intraepithelial lesion 10.2 DRD2 HTR2A SLC6A4
38 partial motor epilepsy 10.2 DRD2 HTR2A SLC6A4
39 parkinsonism-dystonia, infantile 10.2 DRD2 HTR2A SLC6A3
40 hepatopulmonary syndrome 10.2 DRD2 HTR2A SLC6A3
41 laryngeal adductor paralysis 10.2 HTR2A SLC6A4
42 asperger syndrome 10.2 DRD2 SLC6A3
43 pyromania 10.0 DRD2 HTR2A SLC6A3 SLC6A4
44 cecal benign neoplasm 10.0 DRD2 HTR2A SLC6A3 SLC6A4
45 hepatitis d 10.0 DRD2 HTR2A SLC6A3 SLC6A4
46 chronic conjunctivitis 10.0 DRD2 HTR2A SLC6A3 SLC6A4
47 aicardi-goutieres syndrome 2 10.0 DRD2 HTR2A SLC6A3 SLC6A4
48 bone fracture 10.0 DRD2 HTR2A SLC6A3 SLC6A4
49 epileptic encephalopathy, early infantile, 45 10.0 DRD2 HTR2A SLC6A3 SLC6A4
50 sexual disorder 10.0 DRD2 HTR2A SLC6A3 SLC6A4

Graphical network of the top 20 diseases related to Alcoholic Psychosis:



Diseases related to Alcoholic Psychosis

Symptoms & Phenotypes for Alcoholic Psychosis

Drugs & Therapeutics for Alcoholic Psychosis

Drugs for Alcoholic Psychosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 214)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acamprosate Approved, Investigational Phase 4,Phase 2,Phase 1 77337-76-9 71158
2
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 64-17-5 702
3
Disulfiram Approved Phase 4 97-77-8 3117
4
Bupropion Approved Phase 4,Phase 2 34841-39-9, 34911-55-2 444
5
Dopamine Approved Phase 4,Phase 2,Phase 1 51-61-6, 62-31-7 681
6
Fluoxetine Approved, Vet_approved Phase 4 54910-89-3 3386
7
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 16590-41-3 5360515
8
Acetaminophen Approved Phase 4 103-90-2 1983
9
Nicotine Approved Phase 4,Phase 2 54-11-5 942 89594
10
Benzocaine Approved Phase 4,Phase 3 1994-09-7, 94-09-7 2337
11
Sertraline Approved Phase 4,Phase 2,Phase 1 79617-96-2 68617
12
Carbamazepine Approved, Investigational Phase 4 298-46-4 2554
13
Lorazepam Approved Phase 4 846-49-1 3958
14
Icodextrin Approved, Investigational Phase 4 337376-15-5
15
Gabapentin Approved, Investigational Phase 4,Phase 2 60142-96-3 3446
16
Varenicline Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 249296-44-4 5310966
17
Spironolactone Approved Phase 4 1952-01-7, 52-01-7 5833
18
Glutamic Acid Approved, Nutraceutical Phase 4 56-86-0 33032
19
Thiamine Approved, Nutraceutical, Vet_approved Phase 4 59-43-8 1130
20
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
21 tannic acid Approved, Nutraceutical Phase 4,Phase 3
22
gamma-Aminobutyric acid Investigational Phase 4,Phase 2 56-12-2 119
23 Antidepressive Agents Phase 4,Phase 3,Phase 2,Phase 1
24 Antidepressive Agents, Second-Generation Phase 4,Phase 3,Phase 2,Phase 1
25 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
26 Anti-Infective Agents, Local Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
27 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
28 Cytochrome P-450 CYP2D6 Inhibitors Phase 4,Phase 3,Phase 2
29 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 2
30 Dopamine Agents Phase 4,Phase 2,Phase 1
31 Dopamine Uptake Inhibitors Phase 4,Phase 2
32 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Phase 1
33 Neurotransmitter Uptake Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
34 Psychotropic Drugs Phase 4,Phase 3,Phase 2,Phase 1
35
Serotonin Phase 4,Phase 3,Phase 2,Phase 1 50-67-9 5202
36 Serotonin Agents Phase 4,Phase 3,Phase 2,Phase 1
37 Serotonin Uptake Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
38 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
39 Narcotic Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
40 Narcotics Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
41 Central Nervous System Stimulants Phase 4,Phase 1,Phase 2
42 Vitamins Phase 4
43 Anti-Anxiety Agents Phase 4,Phase 2,Phase 1
44 GABA Agents Phase 4,Phase 1,Phase 2
45 GABA Modulators Phase 4,Phase 1
46 Hypnotics and Sedatives Phase 4
47 Tranquilizing Agents Phase 4,Phase 3,Phase 2,Phase 1
48 Analgesics Phase 4,Phase 2
49 Analgesics, Non-Narcotic Phase 4
50 Antipyretics Phase 4

Interventional clinical trials:

(show top 50) (show all 195)

id Name Status NCT ID Phase Drugs
1 Acamprosate vs. Placebo in Bipolar Alcoholics Unknown status NCT00466661 Phase 4 Acamprosate;Placebo
2 Safety of Acamprosate for Alcohol Dependence in the Elderly: An Open-Label Study (SAFADIE) Unknown status NCT00655967 Phase 4 Acamprosate (Campral);Acamprosate
3 Antabuse in Severe Alcoholism: an Open Controlled Study Unknown status NCT00431262 Phase 4 antabuse (disulfiram)
4 Fluoxetine and Bupropion to Treat Patients With Depression and Alcoholism Unknown status NCT00449007 Phase 4 fluoxetine;bupropion
5 Hepatic Function in Alcoholics Following 5 Days of Acetaminophen Dosing Completed NCT00427206 Phase 4 acetaminophen (4g/day);placebo
6 Hepatic Function During and Following Three Days of Acetaminophen Dosing in Alcoholics Completed NCT00402571 Phase 4 acetaminophen
7 Naltrexone Treatment for Alcoholic Women Completed NCT00000448 Phase 4 naltrexone;Placebo
8 Combination Nicotine Replacement for Alcoholic Smokers Completed NCT00064844 Phase 4
9 Behavior and Naltrexone Treatment for Alcoholics Completed NCT00000449 Phase 4 naltrexone (Revia)
10 Bupropion as a Smoking Cessation Aid in Alcoholics Completed NCT00044434 Phase 4 bupropion (Wellbutrin)
11 Naltrexone for Early Problem Drinkers Completed NCT00000455 Phase 4 naltrexone
12 Drug Treatment for Depressed Alcoholics (Naltrexone/Fluoxetine) Completed NCT00006204 Phase 4 naltrexone (Revia);fluoxetine (Prozac)
13 Understanding Treatment Response With Naltrexone Among White Alcoholics Completed NCT00817089 Phase 4 naltrexone;placebo
14 Targeted Naltrexone for Problem Drinkers Completed NCT00369408 Phase 4 Naltrexone;placebo
15 High Dose Vitamin B1 to Reduce Abusive Alcohol Use Completed NCT00680121 Phase 4 Benfotiamine;Placebo
16 Individually Adapted Therapy of Alcoholism Completed NCT00317031 Phase 4 Acamprosate or Naltrexone
17 Sertraline Pharmacotherapy for Alcoholism Subtypes Completed NCT00368550 Phase 4 Sertraline;Placebo
18 Acamprosate: Genes Associated With Response Completed NCT00662571 Phase 4 acamprosate
19 Integrative Therapy in Alcoholism Completed NCT00159107 Phase 4 Acamprosate;Placebo
20 Drug Therapy for Alcohol Detoxification Completed NCT00000441 Phase 4 lorazepam (Ativan);carbamazepine (Tegretol)
21 Behavioral Counseling for Alcohol Dependent Smokers (Nicotine Patch) Completed NCT00004551 Phase 4 nicotine replacement patch
22 Alcohol Detoxification in Primary Care Treatment (ADEPT) Completed NCT00855699 Phase 4 Acamprosate
23 Smoking Cessation in Alcoholism Treatment Completed NCT00000454 Phase 4 nicotine replacement patch
24 Genetic and Brain Mechanisms of Naltrexone's Treatment Efficacy for Alcoholism Completed NCT00920829 Phase 4 Drug;Placebo
25 Acamprosate in Alcoholics With Comorbid Anxiety or Depression Completed NCT00330174 Phase 4 Acamprosate
26 Naltrexone for Heavy Drinking in Young Adults Completed NCT00568958 Phase 4 naltrexone;placebo naltrexone
27 Sertraline for Alcohol Dependence and Depression Completed NCT00004554 Phase 4 naltrexone (Revia);sertraline (Zoloft);Placebo
28 Treatment for Alcohol Dependence With Gabapentin Recruiting NCT02771925 Phase 4 Gabapentin 2g/day divided in two doses for 24 weeks;Placebo 2g/day divided in two doses for 24 weeks
29 Exploration of the Potential Role of Brain Magnetic Stimulation in Preventing Relapse to Alcohol Abuse Not yet recruiting NCT02691390 Phase 4
30 Varenicline Augmentation of Patch Outcomes in Heavy Drinkers' Smoking Cessation Not yet recruiting NCT02859142 Phase 4 Chantix;NicodermCQ
31 Clinical Trial Studying the Effects of Spironolactone on Heart and Skeletal Muscle Function in Chronic Alcoholics Suspended NCT00226109 Phase 4 spironolactone
32 Medication and Counseling for Controlled Drinking Unknown status NCT01115894 Phase 3 Naltrexone;Placebo
33 Making Alcoholics Anonymous Easier Completed NCT01382316 Phase 3
34 Varenicline For Smokers In Recovery From Alcohol Dependence Completed NCT01092702 Phase 2, Phase 3 Varenicline
35 Varenicline Treatment for Active Alcoholic Smokers Completed NCT01347112 Phase 2, Phase 3 Varenicline;placebo
36 Baclofen in the Treatment of Alcohol Dependence With or Without Alcoholic Liver Disease Completed NCT01711125 Phase 3 Baclofen 30mg/day;Baclofen 75mg/day;Placebo
37 Naltrexone & SSRI in Alcoholics With Depression/PTSD Completed NCT00338962 Phase 3 paroxetine;desipramine;Naltrexone;Placebo
38 Quetiapine Fumarate (Seroquel) for the Treatment of Alcohol Dependence. Completed NCT00124059 Phase 3 Seroquel;Placebo
39 Aripiprazole and Topiramate on Free-Choice Alcohol Use Completed NCT00884884 Phase 2, Phase 3 Double Placebo;Aripiprazole 15, placebo;Aripiprazole 7.5, Placebo;Topiramate 100, Placebo;Topiramate 200, Placebo;Topiramate 100, Aripiprazole 15;Topiramate 100, Aripiprazole 7.5;Topiramate 100, Aripiprazole 15mg;Topiramate 200, Aripiprazole 7.5mg;Topiramate 200, Aripiprazole 15
40 A New Pharmacotherapy for Alcohol Dependence: Olanzapine Completed NCT00746785 Phase 3 2.5 mg Olanzapine;5mg Olanzapine;placebo
41 Efficacy and Safety of Levetiracetam in Prevention of Alcohol Relapse in Recently Detoxified Alcohol Dependent Patients Completed NCT00758277 Phase 3 levetiracetam (Keppra);Placebo
42 Web-based Ultra-brief Intervention for Heavy Drinkers Trial Completed NCT00751985 Phase 3
43 Brief Intervention for Heavy Drinkers Completed NCT00728767 Phase 3
44 Promoting Self-Change From Alcohol Problems: Mechanisms of Change in a Community-Based Intervention Completed NCT00732095 Phase 3
45 Baclofen to Prevent Agitation in Alcohol Addicted Patients in ICU Recruiting NCT02723383 Phase 3 BACLOFEN;PLACEBO
46 Nalmefene in Patients With Alcoholic Compensated Cirrhosis for the Treatment of Alcohol Dependence. Not yet recruiting NCT02824354 Phase 3 Nalmefene (Selincro®) 18 mg tablet;placebo
47 Varenicline and Alcohol in Inpatient Addictions Program (IAP) Terminated NCT01169610 Phase 3 Varenicline
48 Efficacy of a Brief Alcohol Intervention for Non Dependant Alcohol-misusing Patients Undergoing a Scheduled Surgery Terminated NCT01348113 Phase 3
49 Residual Effects of Intoxication on Student Performance Unknown status NCT00183170 Phase 2 Beer (alcohol)
50 Pharmacologic Relapse Prevention for Alcoholic Smokers Completed NCT00000457 Phase 2 bupropion (Wellbutrin);Placebo

Search NIH Clinical Center for Alcoholic Psychosis

Cochrane evidence based reviews: psychoses, alcoholic

Genetic Tests for Alcoholic Psychosis

Anatomical Context for Alcoholic Psychosis

MalaCards organs/tissues related to Alcoholic Psychosis:

39
Brain, Liver, Testes, Lung, Heart, Skin, Skeletal Muscle

Publications for Alcoholic Psychosis

Articles related to Alcoholic Psychosis:

id Title Authors Year
1
[The analysis of serotonin receptor type 2A gene polymorphism in patients of different nationalities with acute alcoholic psychosis]. ( 11842624 )
2002
2
[Analysis of insertion-deletion polymorphism in serotonin transporter gene in men of different ethnic appurtenance with acute alcoholic psychosis]. ( 12534269 )
2002
3
[The evaluation of VNTR-polymorphism in the gene of dopamine transporter in men of different nationalities with acute alcoholic psychosis]. ( 11505915 )
2001
4
Haloperidol for acute psychiatric emergencies: a double-blind comparison with perphenazine in acute alcoholic psychosis. ( 4927220 )
1971
5
THE INFLUENCE OF LSD-25 RESEARCH ON AN ALCOHOLIC PSYCHOSIS. ( 14129295 )
1964
6
Post alcoholic psychosis. Report of four cases with unusual characteristics. ( 13925814 )
1962
7
Fat embolism and alcoholic psychosis. ( 13861232 )
1962
8
Histopathology of the mammillary bodies in alcoholic psychosis. ( 13590394 )
1958
9
Experience with reserpine (serpasil) and perphenazine (trilafon) in acute alcoholic intoxications and alcoholic psychosis. ( 13608383 )
1958

Variations for Alcoholic Psychosis

Expression for Alcoholic Psychosis

Search GEO for disease gene expression data for Alcoholic Psychosis.

Pathways for Alcoholic Psychosis

GO Terms for Alcoholic Psychosis

Biological processes related to Alcoholic Psychosis according to GeneCards Suite gene sharing:

(show all 18)
id Name GO ID Score Top Affiliating Genes
1 visual learning GO:0008542 9.58 DRD2 NPS
2 neurotransmitter transport GO:0006836 9.57 SLC6A3 SLC6A4
3 response to nicotine GO:0035094 9.56 DRD2 SLC6A3
4 response to cocaine GO:0042220 9.55 DRD2 SLC6A3
5 release of sequestered calcium ion into cytosol GO:0051209 9.54 DRD2 HTR2A
6 positive regulation of multicellular organism growth GO:0040018 9.52 DRD2 SLC6A3
7 regulation of dopamine secretion GO:0014059 9.51 DRD2 HTR2A
8 behavioral response to cocaine GO:0048148 9.49 DRD2 HTR2A
9 temperature homeostasis GO:0001659 9.48 DRD2 HTR2A
10 response to iron ion GO:0010039 9.46 DRD2 SLC6A3
11 negative regulation of synaptic transmission, glutamatergic GO:0051967 9.43 DRD2 HTR2A
12 neurotransmitter biosynthetic process GO:0042136 9.4 SLC6A3 SLC6A4
13 ammonium transmembrane transport GO:0072488 9.37 SLC6A3 SLC6A4
14 prepulse inhibition GO:0060134 9.32 DRD2 SLC6A3
15 adenohypophysis development GO:0021984 9.26 DRD2 SLC6A3
16 monoamine transport GO:0015844 9.16 SLC6A3 SLC6A4
17 response to drug GO:0042493 9.02 CDK9 DRD2 HTR2A SLC6A3 SLC6A4
18 dopamine uptake involved in synaptic transmission GO:0051583 8.96 SLC6A3 SLC6A4

Molecular functions related to Alcoholic Psychosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 drug binding GO:0008144 9.33 DRD2 HTR2A SLC6A3
2 neurotransmitter:sodium symporter activity GO:0005328 9.32 SLC6A3 SLC6A4
3 dopamine binding GO:0035240 9.26 DRD2 SLC6A3
4 monoamine transmembrane transporter activity GO:0008504 8.96 SLC6A3 SLC6A4
5 dopamine:sodium symporter activity GO:0005330 8.62 SLC6A3 SLC6A4

Sources for Alcoholic Psychosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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