MCID: ALK003
MIFTS: 32

Aleukemic Leukemia Cutis malady

Categories: Cancer diseases, Immune diseases

Aliases & Classifications for Aleukemic Leukemia Cutis

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Aliases & Descriptions for Aleukemic Leukemia Cutis:

Name: Aleukemic Leukemia Cutis 11 13 66

Classifications:



External Ids:

Disease Ontology11 DOID:6003
NCIt43 C4983

Summaries for Aleukemic Leukemia Cutis

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MalaCards based summary: Aleukemic Leukemia Cutis is related to acute myelomonocytic leukemia and myelodysplastic syndrome. An important gene associated with Aleukemic Leukemia Cutis is NPM1 (Nucleophosmin), and among its related pathways are LDL Oxidation in Atherogenesis and Transcriptional misregulation in cancer. Affiliated tissues include monocytes, myeloid and b cells, and related mouse phenotypes are neoplasm and cardiovascular system.

Related Diseases for Aleukemic Leukemia Cutis

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Diseases related to Aleukemic Leukemia Cutis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 82)
idRelated DiseaseScoreTop Affiliating Genes
1acute myelomonocytic leukemia31.1FLT3, NPM1
2myelodysplastic syndrome27.8ANPEP, CD33, CD34, DNTT, FLT3, NPM1
3subleukemic leukemia11.4
4leukemia10.7
5aml with myelodysplasia-related features10.7FLT3, MYH11
6acute panmyelosis with myelofibrosis10.7FLT3, NPM1
7viral laryngitis10.7LYZ, NCAM1
8hyperpituitarism10.7HAVCR1, LYZ
9dyserythropoietic anemia and thrombocytopenia10.7FLT3, NPM1
10malignant adenofibroma10.7HAVCR1, LYZ
11adult acute lymphocytic leukemia10.6FLT3, MPO
12unclassified intestinal pseudoobstruction10.6FLT3, RUNX1
13gastric teratoma10.6CD33, NCAM1
14suppurative uveitis10.6LYZ, MPO
15sezary's disease10.6LYZ, NCAM1, NPM1
16blepharo naso facial syndrome van maldergem type10.6NCAM1, NPM1
17diffuse pulmonary fibrosis10.5CD68, LYZ
18herpes zoster10.4FLT3, LYZ, MPO
19post-surgical hypoinsulinemia10.4LYZ, MPO, SPN
20aniseikonia10.4CD68, NCAM1
21granular cell tumor10.4CD68, NCAM1
22nodular tenosynovitis10.4CD68, LYZ
23lymphoblastic leukemia10.4
24pulmonary alveolar proteinosis10.4LYZ, MPO
25acute kidney failure10.3DNTT, FLT3, MPO
26yellow fever10.3CD68, LYZ, MPO
27kidney rhabdoid cancer10.2CD68, NCAM1
28hilar lung neoplasm10.2CD34, NCAM1
29acute monocytic leukemia10.2
30monocytic leukemia10.2
31myeloid leukemia10.2
32choroiditis10.2CD68, LYZ
33ethmoid sinus cancer10.1CD68, DNTT
34tetanus10.1CD68, NCAM1, SPN
35upper gum cancer10.1CD34, MPO
36congenital myasthenic syndrome10.1DNTT, FUT4
37dens in dente and palatal invaginations10.1CD68, DNTT, MPO
38isthmian coarctation10.1ANPEP, DNTT, RUNX1
39upper lip cancer10.1CD68, FUT4
40acrorenal syndrome10.1CD68, SPN
41tonsillar pillar cancer10.0CD33, FLT3, LYZ, MPO, NPM1
42akinetic mutism10.0CD34, NCAM1
43liver cirrhosis10.0FLT3, NPM1, RARA, RUNX1
44cutaneous mastocytosis10.0
45mastocytosis10.0
46diverticulitis9.9CD7, FUT4, NCAM1
47skeletal muscle cancer9.9CD68, FUT4, LYZ
48critical congenital heart disease9.9FLT3, RUNX1
49intravascular fasciitis9.9CD34, CD68
50malignant type ab thymoma9.9CD34, CD68

Graphical network of the top 20 diseases related to Aleukemic Leukemia Cutis:



Diseases related to aleukemic leukemia cutis

Symptoms for Aleukemic Leukemia Cutis

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Drugs & Therapeutics for Aleukemic Leukemia Cutis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Aleukemic Leukemia Cutis

Genetic Tests for Aleukemic Leukemia Cutis

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Anatomical Context for Aleukemic Leukemia Cutis

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MalaCards organs/tissues related to Aleukemic Leukemia Cutis:

34
Monocytes, Myeloid, B cells, Bone, T cells

Animal Models for Aleukemic Leukemia Cutis or affiliated genes

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MGI Mouse Phenotypes related to Aleukemic Leukemia Cutis:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020067.9CD34, FLT3, LYZ, NPM1, RARA, RUNX1
2MP:00053857.4ANPEP, DNTT, FUT4, LYZ, MPO, MYH11
3MP:00053847.2CD34, FLT3, FUT4, LYZ, MYH11, NCAM1
4MP:00053875.3ANPEP, CD34, CD68, CD7, DNTT, FLT3
5MP:00053975.0ANPEP, CD34, CD68, CD7, DNTT, FLT3

Publications for Aleukemic Leukemia Cutis

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Articles related to Aleukemic Leukemia Cutis:

(show all 26)
idTitleAuthorsYear
1
Aleukemic Leukemia Cutis Presenting as a Sole Sign of Relapsed Paediatric Acute Lymphoblastic Leukemia. (27408353)
2016
2
Pediatric Aleukemic Leukemia Cutis: Report of 3 Cases and Review of the Literature. (25148106)
2014
3
Aleukemic leukemia cutis: an unusual rash in a child. (25035690)
2014
4
Acute myeloid leukemia 7A years after aleukemic leukemia cutis. (24261792)
2013
5
Recurrent aleukemic leukemia cutis in a patient with pre-B-cell acute lymphoblastic leukemia. (23733764)
2013
6
Acute promyelocytic leukemia following aleukemic leukemia cutis harboring NPM/RARA fusion gene. (22573339)
2012
7
Aleukemic leukemia cutis manifesting with disseminated nodular eruptions and a plaque preceding acute monocytic leukemia: a case report. (22187541)
2011
8
Aleukemic leukemia cutis in a child preceding T-cell acute lymphoblastic leukemia. (21895759)
2011
9
Siblings presenting with progressive congenital aleukemic leukemia cutis. (21425444)
2011
10
Aleukemic leukemia cutis with extensive bone involvement. (20708479)
2010
11
Spontaneous regression of aleukemic leukemia cutis harboring a NPM/RARA fusion gene in an infant with cutaneous mastocytosis. (19052694)
2009
12
Aleukemic leukemia cutis preceding acute monocytic leukemia: a case report. (18782972)
2008
13
Aleukemic leukemia cutis. (17456918)
2007
14
Aleukemic leukemia cutis in a patient with Philadelphia chromosome-positive biphenotypic leukemia. (15540904)
2004
15
Guess what. B-cell acute lymphoblastic leukemia with aleukemic leukemia cutis. (11275816)
2001
16
Aleukemic leukemia cutis presenting as benign-appearing exanthema. (11411915)
2001
17
Monocytic aleukemic leukemia cutis. (10565632)
1999
18
Aleukemic leukemia cutis in an adolescent boy. (10084909)
1999
19
Aleukemic leukemia cutis in a patient with acute lymphoblastic leukemia. (9555803)
1998
20
Aleukemic leukemia cutis preceding overt acute myeloid leukemia in myelodysplastic syndrome. (8980276)
1997
21
Lymphocytic aleukemic leukemia cutis. (8912603)
1996
22
Aleukemic leukemia cutis. (2406302)
1990
23
Aleukemic leukemia cutis. (3729513)
1986
24
Aleukemic leukemia cutis. An unusual presentation of acute myelomonocytic leukemia. (2943614)
1986
25
Aleukemic leukemia cutis: juvenile chronic granulocytic leukemia presenting with figurate cutaneous lesions. (6579062)
1983
26
Aleukemic leukemia cutis. (1062968)
1976

Variations for Aleukemic Leukemia Cutis

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Expression for genes affiliated with Aleukemic Leukemia Cutis

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Search GEO for disease gene expression data for Aleukemic Leukemia Cutis.

Pathways for genes affiliated with Aleukemic Leukemia Cutis

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GO Terms for genes affiliated with Aleukemic Leukemia Cutis

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Cellular components related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098978.3ANPEP, CD33, CD34, NCAM1, SPN
2cell surfaceGO:00099868.0CD34, FUT4, NCAM1, RARA, SPN

Biological processes related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hematopoietic stem cell proliferationGO:00714259.6CD34, RUNX1
2viral entry into host cellGO:00467189.4ANPEP, HAVCR1, NCAM1
3regulation of immune responseGO:00507768.9CD33, CD34, SPN
4hemopoiesisGO:00300978.7CD34, FLT3, RUNX1

Molecular functions related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulatory region DNA bindingGO:00009759.9RARA, RUNX1
2virus receptor activityGO:00016189.4ANPEP, HAVCR1, NCAM1

Sources for Aleukemic Leukemia Cutis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet