MCID: ALK003
MIFTS: 31

Aleukemic Leukemia Cutis malady

Categories: Cancer diseases, Immune diseases

Aliases & Classifications for Aleukemic Leukemia Cutis

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Aliases & Descriptions for Aleukemic Leukemia Cutis:

Name: Aleukemic Leukemia Cutis 11 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:6003
NCIt45 C4983

Summaries for Aleukemic Leukemia Cutis

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MalaCards based summary: Aleukemic Leukemia Cutis is related to subleukemic leukemia and leukemia. An important gene associated with Aleukemic Leukemia Cutis is NPM1 (Nucleophosmin), and among its related pathways are Wnt/beta-catenin Signaling Pathway in Leukemia and LDL Oxidation in Atherogenesis. Affiliated tissues include monocytes, myeloid and b cells, and related mouse phenotypes are cardiovascular system and neoplasm.

Related Diseases for Aleukemic Leukemia Cutis

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Diseases related to Aleukemic Leukemia Cutis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 58)
idRelated DiseaseScoreTop Affiliating Genes
1subleukemic leukemia11.3
2leukemia10.6
3acute motor-sensory axonal neuropathy10.3FLT3, MPO
4acute zonal occult outer retinopathy10.3FLT3, NPM1
5lymphoblastic leukemia10.2
6unilateral hemispheric polymicrogyria10.2FLT3, RUNX1
7acute respiratory distress syndrome10.2FLT3, NPM1
8glycogen storage disease type 010.2FLT3, NPM1
9acute necrotizing encephalopathy10.2ANPEP, MPO
10dancing eyes-dancing feet syndrome10.2ELANE, MPO
11acute perichondritis of pinna10.1LYZ, MPO, SPN
12cavernous hemangioma of colon10.1CD34, NCAM1
13actinobacillosis10.1FLT3, MPO, RUNX1
14acute leukemia10.1DNTT, FLT3, MPO
15acute monocytic leukemia10.0
16monocytic leukemia10.0
17myeloid leukemia10.0
18active peptic ulcer disease10.0CD7, FUT4, NCAM1
19thompson baraitser syndrome10.0ANPEP, DNTT, RUNX1
20lymphoma, small cleaved-cell, diffuse10.0CD7, DNTT, MPO
21chiasmal syndrome10.0CD68, LYZ
22mammary paget's disease10.0CD68, LYZ, NCAM1
23rosacea conjunctivitis10.0CD68, LYZ, MPO
24hemophagocytic lymphohistiocytosis10.0DNTT, FLT3, NPM1, RUNX1
25pneumocystosis9.9CD68, NCAM1, SPN
26spermatocytoma9.9CD34, DNTT, NCAM1
27neurofibromatosis9.9DNTT, FLT3, MPO, NCAM1, NPM1
28adducted thumbs dundar type9.9DNTT, FLT3, MPO, MYH11, RUNX1
29milker's nodule9.9CD33, FLT3, MYH11, NPM1, RARA, RUNX1
30myelodysplastic syndrome9.9
31cutaneous mastocytosis9.9
32mastocytosis9.9
33hemangioma of liver9.9CD68, LYZ
34desmoid tumor9.9CD68, DNTT, MPO
35hemopneumothorax9.9CD34, CD68
36liver rhabdomyosarcoma9.9CD68, FUT4, LYZ
37adult spinal cord ependymoma9.9CD34, CD68, MPO
38freemartinism9.9CD33, CD34, CD68
39heavy chain disease9.9CD34, CD68, HAVCR1
40demyelinating disease9.8CD34, CD68, LYZ
41hyperphosphatasia with mental retardation syndrome 29.8ANPEP, DNTT, FLT3, MPO, RUNX1
42pulmonary fibrosis, idiopathic9.8CD34, DNTT, NPM1, SPN
43bilateral breast cancer9.8CD34, CD68
44choriocarcinoma of ovary9.8CD34, CD68
45jewett-marshall bladder cancer9.8CD34, CD68, HAVCR1, LYZ
46nutritional deficiency disease9.7CD34, CD68, FUT4
47peroxisome biogenesis disorder 7a9.7CD33, CD34, DNTT, FLT3, RUNX1
48pleural lipoma9.7CD34, CD68, DNTT
49tactile epilepsy9.7CD34, CD68, FUT4
50laryngeal adenoid cystic carcinoma9.7CD34, CD68

Graphical network of the top 20 diseases related to Aleukemic Leukemia Cutis:



Diseases related to aleukemic leukemia cutis

Symptoms & Phenotypes for Aleukemic Leukemia Cutis

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MGI Mouse Phenotypes related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053858.2ANPEP, DNTT, FUT4, LYZ, MPO, MYH11
2MP:00020067.8CD34, ELANE, FLT3, LYZ, NPM1, RARA
3MP:00053975.6ANPEP, CD34, CD68, CD7, DNTT, ELANE
4MP:00053875.5ANPEP, CD34, CD68, CD7, DNTT, ELANE

Drugs & Therapeutics for Aleukemic Leukemia Cutis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Aleukemic Leukemia Cutis

Genetic Tests for Aleukemic Leukemia Cutis

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Anatomical Context for Aleukemic Leukemia Cutis

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MalaCards organs/tissues related to Aleukemic Leukemia Cutis:

36
Monocytes, Myeloid, B cells, Bone, T cells

Publications for Aleukemic Leukemia Cutis

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Articles related to Aleukemic Leukemia Cutis:

(show all 26)
idTitleAuthorsYear
1
Aleukemic Leukemia Cutis Presenting as a Sole Sign of Relapsed Paediatric Acute Lymphoblastic Leukemia. (27408353)
2016
2
Pediatric Aleukemic Leukemia Cutis: Report of 3 Cases and Review of the Literature. (25148106)
2014
3
Aleukemic leukemia cutis: an unusual rash in a child. (25035690)
2014
4
Recurrent aleukemic leukemia cutis in a patient with pre-B-cell acute lymphoblastic leukemia. (23733764)
2013
5
Acute myeloid leukemia 7A years after aleukemic leukemia cutis. (24261792)
2013
6
Acute promyelocytic leukemia following aleukemic leukemia cutis harboring NPM/RARA fusion gene. (22573339)
2012
7
Aleukemic leukemia cutis manifesting with disseminated nodular eruptions and a plaque preceding acute monocytic leukemia: a case report. (22187541)
2011
8
Aleukemic leukemia cutis in a child preceding T-cell acute lymphoblastic leukemia. (21895759)
2011
9
Siblings presenting with progressive congenital aleukemic leukemia cutis. (21425444)
2011
10
Aleukemic leukemia cutis with extensive bone involvement. (20708479)
2010
11
Spontaneous regression of aleukemic leukemia cutis harboring a NPM/RARA fusion gene in an infant with cutaneous mastocytosis. (19052694)
2009
12
Aleukemic leukemia cutis preceding acute monocytic leukemia: a case report. (18782972)
2008
13
Aleukemic leukemia cutis. (17456918)
2007
14
Aleukemic leukemia cutis in a patient with Philadelphia chromosome-positive biphenotypic leukemia. (15540904)
2004
15
Aleukemic leukemia cutis presenting as benign-appearing exanthema. (11411915)
2001
16
Guess what. B-cell acute lymphoblastic leukemia with aleukemic leukemia cutis. (11275816)
2001
17
Aleukemic leukemia cutis in an adolescent boy. (10084909)
1999
18
Monocytic aleukemic leukemia cutis. (10565632)
1999
19
Aleukemic leukemia cutis in a patient with acute lymphoblastic leukemia. (9555803)
1998
20
Aleukemic leukemia cutis preceding overt acute myeloid leukemia in myelodysplastic syndrome. (8980276)
1997
21
Lymphocytic aleukemic leukemia cutis. (8912603)
1996
22
Aleukemic leukemia cutis. (2406302)
1990
23
Aleukemic leukemia cutis. An unusual presentation of acute myelomonocytic leukemia. (2943614)
1986
24
Aleukemic leukemia cutis. (3729513)
1986
25
Aleukemic leukemia cutis: juvenile chronic granulocytic leukemia presenting with figurate cutaneous lesions. (6579062)
1983
26
Aleukemic leukemia cutis. (1062968)
1976

Variations for Aleukemic Leukemia Cutis

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Expression for genes affiliated with Aleukemic Leukemia Cutis

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Search GEO for disease gene expression data for Aleukemic Leukemia Cutis.

Pathways for genes affiliated with Aleukemic Leukemia Cutis

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GO Terms for genes affiliated with Aleukemic Leukemia Cutis

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Cellular components related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1azurophil granule lumenGO:003557810.4ELANE, LYZ, MPO
2external side of plasma membraneGO:00098979.3ANPEP, CD33, CD34, NCAM1, SPN
3cell surfaceGO:00099868.9CD34, ELANE, FUT4, NCAM1, RARA, SPN
4extracellular exosomeGO:00700627.7ANPEP, CD33, CD7, ELANE, LYZ, MPO

Biological processes related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of growth of symbiont in hostGO:004413010.6ELANE, MPO
2response to yeastGO:000187810.5ELANE, MPO
3hematopoietic stem cell proliferationGO:007142510.3CD34, RUNX1
4defense response to bacteriumGO:004274210.0ELANE, LYZ, MPO, SPN
5hemopoiesisGO:00300979.9CD34, FLT3, RUNX1
6viral entry into host cellGO:00467189.6ANPEP, HAVCR1, NCAM1
7neutrophil degranulationGO:00433128.6ANPEP, CD33, CD68, ELANE, LYZ, MPO

Molecular functions related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulatory region DNA bindingGO:000097510.4RARA, RUNX1
2virus receptor activityGO:00016189.6ANPEP, HAVCR1, NCAM1

Sources for Aleukemic Leukemia Cutis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet