MCID: ALK003
MIFTS: 31

Aleukemic Leukemia Cutis malady

Categories: Cancer diseases, Immune diseases

Aliases & Classifications for Aleukemic Leukemia Cutis

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Aliases & Descriptions for Aleukemic Leukemia Cutis:

Name: Aleukemic Leukemia Cutis 11 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:6003
NCIt45 C4983

Summaries for Aleukemic Leukemia Cutis

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MalaCards based summary: Aleukemic Leukemia Cutis is related to myelodysplastic syndrome and subleukemic leukemia. An important gene associated with Aleukemic Leukemia Cutis is NPM1 (Nucleophosmin), and among its related pathways are LDL Oxidation in Atherogenesis and Cell adhesion molecules (CAMs). Affiliated tissues include monocytes, myeloid and b cells, and related mouse phenotypes are cardiovascular system and neoplasm.

Related Diseases for Aleukemic Leukemia Cutis

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Diseases related to Aleukemic Leukemia Cutis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 77)
idRelated DiseaseScoreTop Affiliating Genes
1myelodysplastic syndrome27.9ANPEP, CD33, CD34, DNTT, FLT3, NPM1
2subleukemic leukemia11.3
3aml with myelodysplasia-related features10.6FLT3, MYH11
4leukemia10.6
5viral laryngitis10.6LYZ, NCAM1
6acute panmyelosis with myelofibrosis10.6FLT3, NPM1
7hyperpituitarism10.6HAVCR1, LYZ
8dyserythropoietic anemia and thrombocytopenia10.6FLT3, NPM1
9malignant adenofibroma10.6HAVCR1, LYZ
10placenta praevia10.6ELANE, MPO
11lemierre's syndrome10.6ELANE, LYZ
12adult acute lymphocytic leukemia10.6FLT3, MPO
13unclassified intestinal pseudoobstruction10.6FLT3, RUNX1
14gastric teratoma10.5CD33, NCAM1
15sezary's disease10.5LYZ, NCAM1, NPM1
16febrile seizures, familial, 210.4ELANE, MPO
17proliferative glomerulonephritis10.4ELANE, MPO
18diffuse pulmonary fibrosis10.4CD68, LYZ
19herpes zoster10.4FLT3, LYZ, MPO
20suppurative uveitis10.4LYZ, MPO
21post-surgical hypoinsulinemia10.4LYZ, MPO, SPN
22aniseikonia10.3CD68, NCAM1
23granular cell tumor10.3CD68, NCAM1
24nodular tenosynovitis10.3CD68, LYZ
25acute kidney failure10.3DNTT, FLT3, MPO
26lymphoblastic leukemia10.2
27yellow fever10.2CD68, LYZ, MPO
28blepharo naso facial syndrome van maldergem type10.2NCAM1, NPM1
29hilar lung neoplasm10.1CD34, NCAM1
30tetanus10.1CD68, NCAM1, SPN
31upper gum cancer10.1CD34, MPO
32dens in dente and palatal invaginations10.1CD68, DNTT, MPO
33isthmian coarctation10.1ANPEP, DNTT, RUNX1
34acute monocytic leukemia10.0
35monocytic leukemia10.0
36myeloid leukemia10.0
37kidney rhabdoid cancer10.0CD68, NCAM1
38upper lip cancer10.0CD68, FUT4
39tonsillar pillar cancer10.0CD33, FLT3, LYZ, MPO, NPM1
40complex partial epilepsy10.0ELANE, MPO
41congenital myasthenic syndrome10.0DNTT, FUT4
42liver cirrhosis10.0FLT3, NPM1, RARA, RUNX1
43hyperlucent lung9.9CD34, ELANE
44diverticulitis9.9CD7, FUT4, NCAM1
45skeletal muscle cancer9.9CD68, FUT4, LYZ
46akinetic mutism9.9CD34, NCAM1
47ethmoid sinus cancer9.9CD68, DNTT
48cutaneous mastocytosis9.9
49mastocytosis9.9
50intravascular fasciitis9.9CD34, CD68

Graphical network of the top 20 diseases related to Aleukemic Leukemia Cutis:



Diseases related to aleukemic leukemia cutis

Symptoms & Phenotypes for Aleukemic Leukemia Cutis

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MGI Mouse Phenotypes related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053858.2ANPEP, DNTT, FUT4, LYZ, MPO, MYH11
2MP:00020067.6CD34, ELANE, FLT3, LYZ, NPM1, RARA
3MP:00053975.6ANPEP, CD34, CD68, CD7, DNTT, ELANE
4MP:00053875.5ANPEP, CD34, CD68, CD7, DNTT, ELANE

Drugs & Therapeutics for Aleukemic Leukemia Cutis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Aleukemic Leukemia Cutis

Genetic Tests for Aleukemic Leukemia Cutis

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Anatomical Context for Aleukemic Leukemia Cutis

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MalaCards organs/tissues related to Aleukemic Leukemia Cutis:

36
Monocytes, Myeloid, B cells, Bone, T cells

Publications for Aleukemic Leukemia Cutis

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Articles related to Aleukemic Leukemia Cutis:

(show all 26)
idTitleAuthorsYear
1
Aleukemic Leukemia Cutis Presenting as a Sole Sign of Relapsed Paediatric Acute Lymphoblastic Leukemia. (27408353)
2016
2
Pediatric Aleukemic Leukemia Cutis: Report of 3 Cases and Review of the Literature. (25148106)
2014
3
Aleukemic leukemia cutis: an unusual rash in a child. (25035690)
2014
4
Acute myeloid leukemia 7A years after aleukemic leukemia cutis. (24261792)
2013
5
Recurrent aleukemic leukemia cutis in a patient with pre-B-cell acute lymphoblastic leukemia. (23733764)
2013
6
Acute promyelocytic leukemia following aleukemic leukemia cutis harboring NPM/RARA fusion gene. (22573339)
2012
7
Aleukemic leukemia cutis manifesting with disseminated nodular eruptions and a plaque preceding acute monocytic leukemia: a case report. (22187541)
2011
8
Aleukemic leukemia cutis in a child preceding T-cell acute lymphoblastic leukemia. (21895759)
2011
9
Siblings presenting with progressive congenital aleukemic leukemia cutis. (21425444)
2011
10
Aleukemic leukemia cutis with extensive bone involvement. (20708479)
2010
11
Spontaneous regression of aleukemic leukemia cutis harboring a NPM/RARA fusion gene in an infant with cutaneous mastocytosis. (19052694)
2009
12
Aleukemic leukemia cutis preceding acute monocytic leukemia: a case report. (18782972)
2008
13
Aleukemic leukemia cutis. (17456918)
2007
14
Aleukemic leukemia cutis in a patient with Philadelphia chromosome-positive biphenotypic leukemia. (15540904)
2004
15
Guess what. B-cell acute lymphoblastic leukemia with aleukemic leukemia cutis. (11275816)
2001
16
Aleukemic leukemia cutis presenting as benign-appearing exanthema. (11411915)
2001
17
Monocytic aleukemic leukemia cutis. (10565632)
1999
18
Aleukemic leukemia cutis in an adolescent boy. (10084909)
1999
19
Aleukemic leukemia cutis in a patient with acute lymphoblastic leukemia. (9555803)
1998
20
Aleukemic leukemia cutis preceding overt acute myeloid leukemia in myelodysplastic syndrome. (8980276)
1997
21
Lymphocytic aleukemic leukemia cutis. (8912603)
1996
22
Aleukemic leukemia cutis. (2406302)
1990
23
Aleukemic leukemia cutis. (3729513)
1986
24
Aleukemic leukemia cutis. An unusual presentation of acute myelomonocytic leukemia. (2943614)
1986
25
Aleukemic leukemia cutis: juvenile chronic granulocytic leukemia presenting with figurate cutaneous lesions. (6579062)
1983
26
Aleukemic leukemia cutis. (1062968)
1976

Variations for Aleukemic Leukemia Cutis

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Expression for genes affiliated with Aleukemic Leukemia Cutis

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Search GEO for disease gene expression data for Aleukemic Leukemia Cutis.

Pathways for genes affiliated with Aleukemic Leukemia Cutis

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GO Terms for genes affiliated with Aleukemic Leukemia Cutis

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Cellular components related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.0ANPEP, CD33, CD34, NCAM1, SPN
2cell surfaceGO:00099868.5CD34, ELANE, FUT4, NCAM1, RARA, SPN
3extracellular exosomeGO:00700627.6ANPEP, CD33, CD7, ELANE, LYZ, MPO

Biological processes related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of growth of symbiont in hostGO:004413010.4ELANE, MPO
2response to yeastGO:000187810.4ELANE, MPO
3defense response to bacteriumGO:004274210.2ELANE, LYZ, SPN
4hematopoietic stem cell proliferationGO:007142510.0CD34, RUNX1
5hemopoiesisGO:00300979.6CD34, FLT3, RUNX1
6leukocyte migrationGO:00509009.5CD34, ELANE, SPN
7viral entry into host cellGO:00467189.5ANPEP, HAVCR1, NCAM1

Molecular functions related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulatory region DNA bindingGO:000097510.3RARA, RUNX1
2virus receptor activityGO:00016189.5ANPEP, HAVCR1, NCAM1

Sources for Aleukemic Leukemia Cutis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet