MCID: ALK003
MIFTS: 31

Aleukemic Leukemia Cutis malady

Categories: Cancer diseases, Immune diseases

Aliases & Classifications for Aleukemic Leukemia Cutis

Aliases & Descriptions for Aleukemic Leukemia Cutis:

Name: Aleukemic Leukemia Cutis 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:6003
NCIt 47 C4983
UMLS 69 C0887846

Summaries for Aleukemic Leukemia Cutis

MalaCards based summary : Aleukemic Leukemia Cutis is related to subleukemic leukemia and leukemia. An important gene associated with Aleukemic Leukemia Cutis is NPM1 (Nucleophosmin), and among its related pathways/superpathways are NF-kappaB Signaling and Transcriptional misregulation in cancer. Affiliated tissues include monocytes, myeloid and b cells, and related phenotypes are hematopoietic system and cardiovascular system

Related Diseases for Aleukemic Leukemia Cutis

Diseases related to Aleukemic Leukemia Cutis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 58)
id Related Disease Score Top Affiliating Genes
1 subleukemic leukemia 11.3
2 leukemia 10.6
3 acute motor-sensory axonal neuropathy 10.3 FLT3 MPO
4 acute zonal occult outer retinopathy 10.3 FLT3 NPM1
5 lymphoblastic leukemia 10.2
6 unilateral hemispheric polymicrogyria 10.2 FLT3 RUNX1
7 acute respiratory distress syndrome 10.2 FLT3 NPM1
8 glycogen storage disease type 0 10.2 FLT3 NPM1
9 acute necrotizing encephalopathy 10.2 ANPEP MPO
10 dancing eyes-dancing feet syndrome 10.2 ELANE MPO
11 acute perichondritis of pinna 10.1 LYZ MPO SPN
12 cavernous hemangioma of colon 10.1 CD34 NCAM1
13 actinobacillosis 10.1 FLT3 MPO RUNX1
14 acute leukemia 10.1 DNTT FLT3 MPO
15 acute monocytic leukemia 10.0
16 monocytic leukemia 10.0
17 myeloid leukemia 10.0
18 active peptic ulcer disease 10.0 CD7 FUT4 NCAM1
19 thompson baraitser syndrome 10.0 ANPEP DNTT RUNX1
20 lymphoma, small cleaved-cell, diffuse 10.0 CD7 DNTT MPO
21 chiasmal syndrome 10.0 CD68 LYZ
22 mammary paget's disease 10.0 CD68 LYZ NCAM1
23 rosacea conjunctivitis 10.0 CD68 LYZ MPO
24 hemophagocytic lymphohistiocytosis 10.0 DNTT FLT3 NPM1 RUNX1
25 pneumocystosis 9.9 CD68 NCAM1 SPN
26 spermatocytoma 9.9 CD34 DNTT NCAM1
27 neurofibromatosis 9.9 DNTT FLT3 MPO NCAM1 NPM1
28 adducted thumbs dundar type 9.9 DNTT FLT3 MPO MYH11 RUNX1
29 milker's nodule 9.9 CD33 FLT3 MYH11 NPM1 RARA RUNX1
30 myelodysplastic syndrome 9.9
31 cutaneous mastocytosis 9.9
32 mastocytosis 9.9
33 hemangioma of liver 9.9 CD68 LYZ
34 desmoid tumor 9.9 CD68 DNTT MPO
35 hemopneumothorax 9.9 CD34 CD68
36 liver rhabdomyosarcoma 9.9 CD68 FUT4 LYZ
37 adult spinal cord ependymoma 9.9 CD34 CD68 MPO
38 freemartinism 9.9 CD33 CD34 CD68
39 heavy chain disease 9.9 CD34 CD68 HAVCR1
40 demyelinating disease 9.8 CD34 CD68 LYZ
41 hyperphosphatasia with mental retardation syndrome 2 9.8 ANPEP DNTT FLT3 MPO RUNX1
42 pulmonary fibrosis, idiopathic 9.8 CD34 DNTT NPM1 SPN
43 bilateral breast cancer 9.8 CD34 CD68
44 choriocarcinoma of ovary 9.8 CD34 CD68
45 jewett-marshall bladder cancer 9.8 CD34 CD68 HAVCR1 LYZ
46 nutritional deficiency disease 9.7 CD34 CD68 FUT4
47 peroxisome biogenesis disorder 7a 9.7 CD33 CD34 DNTT FLT3 RUNX1
48 pleural lipoma 9.7 CD34 CD68 DNTT
49 tactile epilepsy 9.7 CD34 CD68 FUT4
50 laryngeal adenoid cystic carcinoma 9.7 CD34 CD68

Graphical network of the top 20 diseases related to Aleukemic Leukemia Cutis:



Diseases related to Aleukemic Leukemia Cutis

Symptoms & Phenotypes for Aleukemic Leukemia Cutis

MGI Mouse Phenotypes related to Aleukemic Leukemia Cutis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10 ANPEP CD34 CD68 CD7 DNTT ELANE
2 cardiovascular system MP:0005385 9.91 ANPEP DNTT FUT4 LYZ MPO MYH11
3 immune system MP:0005387 9.8 ELANE FLT3 FUT4 LYZ MPO NPM1
4 neoplasm MP:0002006 9.23 CD34 ELANE FLT3 LYZ NPM1 RARA

Drugs & Therapeutics for Aleukemic Leukemia Cutis

Search Clinical Trials , NIH Clinical Center for Aleukemic Leukemia Cutis

Genetic Tests for Aleukemic Leukemia Cutis

Anatomical Context for Aleukemic Leukemia Cutis

MalaCards organs/tissues related to Aleukemic Leukemia Cutis:

39
Monocytes, Myeloid, B Cells, T Cells, Bone

Publications for Aleukemic Leukemia Cutis

Articles related to Aleukemic Leukemia Cutis:

(show all 26)
id Title Authors Year
1
Aleukemic Leukemia Cutis Presenting as a Sole Sign of Relapsed Paediatric Acute Lymphoblastic Leukemia. ( 27408353 )
2016
2
Pediatric Aleukemic Leukemia Cutis: Report of 3 Cases and Review of the Literature. ( 25148106 )
2014
3
Aleukemic leukemia cutis: an unusual rash in a child. ( 25035690 )
2014
4
Recurrent aleukemic leukemia cutis in a patient with pre-B-cell acute lymphoblastic leukemia. ( 23733764 )
2013
5
Acute myeloid leukemia 7A years after aleukemic leukemia cutis. ( 24261792 )
2013
6
Acute promyelocytic leukemia following aleukemic leukemia cutis harboring NPM/RARA fusion gene. ( 22573339 )
2012
7
Aleukemic leukemia cutis manifesting with disseminated nodular eruptions and a plaque preceding acute monocytic leukemia: a case report. ( 22187541 )
2011
8
Aleukemic leukemia cutis in a child preceding T-cell acute lymphoblastic leukemia. ( 21895759 )
2011
9
Siblings presenting with progressive congenital aleukemic leukemia cutis. ( 21425444 )
2011
10
Aleukemic leukemia cutis with extensive bone involvement. ( 20708479 )
2010
11
Spontaneous regression of aleukemic leukemia cutis harboring a NPM/RARA fusion gene in an infant with cutaneous mastocytosis. ( 19052694 )
2009
12
Aleukemic leukemia cutis preceding acute monocytic leukemia: a case report. ( 18782972 )
2008
13
Aleukemic leukemia cutis. ( 17456918 )
2007
14
Aleukemic leukemia cutis in a patient with Philadelphia chromosome-positive biphenotypic leukemia. ( 15540904 )
2004
15
Aleukemic leukemia cutis presenting as benign-appearing exanthema. ( 11411915 )
2001
16
Guess what. B-cell acute lymphoblastic leukemia with aleukemic leukemia cutis. ( 11275816 )
2001
17
Aleukemic leukemia cutis in an adolescent boy. ( 10084909 )
1999
18
Monocytic aleukemic leukemia cutis. ( 10565632 )
1999
19
Aleukemic leukemia cutis in a patient with acute lymphoblastic leukemia. ( 9555803 )
1998
20
Aleukemic leukemia cutis preceding overt acute myeloid leukemia in myelodysplastic syndrome. ( 8980276 )
1997
21
Lymphocytic aleukemic leukemia cutis. ( 8912603 )
1996
22
Aleukemic leukemia cutis. ( 2406302 )
1990
23
Aleukemic leukemia cutis. An unusual presentation of acute myelomonocytic leukemia. ( 2943614 )
1986
24
Aleukemic leukemia cutis. ( 3729513 )
1986
25
Aleukemic leukemia cutis: juvenile chronic granulocytic leukemia presenting with figurate cutaneous lesions. ( 6579062 )
1983
26
Aleukemic leukemia cutis. ( 1062968 )
1976

Variations for Aleukemic Leukemia Cutis

Expression for Aleukemic Leukemia Cutis

Search GEO for disease gene expression data for Aleukemic Leukemia Cutis.

Pathways for Aleukemic Leukemia Cutis

GO Terms for Aleukemic Leukemia Cutis

Cellular components related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.91 ANPEP CD33 CD7 ELANE LYZ MPO
2 cell surface GO:0009986 9.43 CD34 ELANE FUT4 NCAM1 RARA SPN
3 azurophil granule lumen GO:0035578 9.33 ELANE LYZ MPO
4 external side of plasma membrane GO:0009897 9.02 ANPEP CD33 CD34 NCAM1 SPN

Biological processes related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 viral entry into host cell GO:0046718 9.5 ANPEP HAVCR1 NCAM1
2 defense response to bacterium GO:0042742 9.46 ELANE LYZ MPO SPN
3 hemopoiesis GO:0030097 9.43 CD34 FLT3 RUNX1
4 negative regulation of growth of symbiont in host GO:0044130 9.4 ELANE MPO
5 hematopoietic stem cell proliferation GO:0071425 9.37 CD34 RUNX1
6 neutrophil degranulation GO:0043312 9.1 ANPEP CD33 CD68 ELANE LYZ MPO
7 response to yeast GO:0001878 8.96 ELANE MPO

Molecular functions related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 regulatory region DNA binding GO:0000975 8.96 RARA RUNX1
2 virus receptor activity GO:0001618 8.8 ANPEP HAVCR1 NCAM1

Sources for Aleukemic Leukemia Cutis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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