MCID: ALK003
MIFTS: 31

Aleukemic Leukemia Cutis malady

Categories: Cancer diseases, Immune diseases

Aliases & Classifications for Aleukemic Leukemia Cutis

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Aliases & Descriptions for Aleukemic Leukemia Cutis:

Name: Aleukemic Leukemia Cutis 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:6003
NCIt42 C4983
UMLS65 C0887846

Summaries for Aleukemic Leukemia Cutis

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MalaCards based summary: Aleukemic Leukemia Cutis is related to subleukemic leukemia and breast cyst. An important gene associated with Aleukemic Leukemia Cutis is NPM1 (Nucleophosmin (Nucleolar Phosphoprotein B23, Numatrin)), and among its related pathways are LDL Oxidation in Atherogenesis and Transcriptional misregulation in cancer. Affiliated tissues include prostate, temporal lobe and b cells, and related mouse phenotypes are tumorigenesis and cardiovascular system.

Related Diseases for Aleukemic Leukemia Cutis

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Diseases related to Aleukemic Leukemia Cutis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 105)
idRelated DiseaseScoreTop Affiliating Genes
1subleukemic leukemia11.8
2breast cyst10.5MPO, NCAM1
3acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)10.5FLT3, NPM1
4acute myeloblastic leukemia without maturation10.5FLT3, NPM1
5blepharo naso facial syndrome van maldergem type10.5NCAM1, NPM1
6frontal sinus squamous cell carcinoma10.5HAVCR1, LYZ
7distal hereditary motor neuropathy, type ii10.5FLT3, NPM1
8mediastinal mesenchymal tumor10.5CD33, NCAM1
9female reproductive organ cancer10.4MYH11, NCAM1
10inclusion body myositis10.4LYZ, NCAM1
11acute myeloid leukemia and myelodysplastic syndromes related to topoisomerase type 2 inhibitor10.4FLT3, RUNX1
12crescentic glomerulonephritis10.4LYZ, MPO
13alg1-congenital disorder of glycosylation10.4FLT3, RUNX1
14hemosiderosis10.4LYZ, MPO
15acute lymphoblastic leukemia congenital sporadic aniridia10.3ANPEP, MPO
16corticosterone methyloxidase deficiency10.3FLT3, RUNX1
17classic hodgkin lymphoma, mixed cellularity type10.3FLT3, RUNX1
18primary systemic mycosis10.3CD68, NCAM1
19skin granular cell tumor10.3CD68, NCAM1
20rete testis neoplasm10.3CD68, LYZ
21rhabdoid cancer10.3CD68, NCAM1
22ductal carcinoma in situ10.3LYZ, NPM1
23mucinous adenofibroma10.3CD68, LYZ
24pheochromocytoma10.3
25hepatitis c virus10.3
26hemochromatosis10.3
27thyroxine-binding globulin deficiency10.3
28bipolar disorder10.3
29hepatitis10.3
30paraganglioma10.3
31lymphoma10.3
32sclerosing cholangitis10.3
33neuroendocrine tumor10.3
34hepatitis c10.3
35acromegaly10.3
36cryoglobulinemia10.3
37pseudohermaphroditism10.3
38arteriolosclerosis10.3
39hyperthyroidism10.3
40peritonitis10.3
41cholangitis10.3
42hemangioendothelioma10.3
43spastic paraparesis10.3
44spasticity10.3
45epithelioid hemangioendothelioma10.3
46pericardial tuberculosis10.3FLT3, MPO, RUNX1
47hematopoietic stem cell transplantation10.2FLT3, NPM1, RUNX1
48primary angle-closure glaucoma10.2CD68, LYZ
49duodenal ulcer10.2CD68, HAVCR1
50burning mouth syndrome10.2CD68, LYZ

Graphical network of the top 20 diseases related to Aleukemic Leukemia Cutis:



Diseases related to aleukemic leukemia cutis

Symptoms for Aleukemic Leukemia Cutis

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Drugs & Therapeutics for Aleukemic Leukemia Cutis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Aleukemic Leukemia Cutis

Genetic Tests for Aleukemic Leukemia Cutis

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Anatomical Context for Aleukemic Leukemia Cutis

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MalaCards organs/tissues related to Aleukemic Leukemia Cutis:

33
Prostate, Temporal lobe, B cells

Animal Models for Aleukemic Leukemia Cutis or affiliated genes

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MGI Mouse Phenotypes related to Aleukemic Leukemia Cutis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.0CD34, FLT3, LYZ, NPM1, RARA, RUNX1
2MP:00053857.5ANPEP, FUT4, LYZ, MPO, MYH11, NPM1
3MP:00053847.1CD34, FLT3, FUT4, LYZ, MYH11, NCAM1
4MP:00053975.3ANPEP, CD34, CD68, CD7, FLT3, FUT4
5MP:00053875.0ANPEP, CD34, CD68, CD7, FLT3, FUT4

Publications for Aleukemic Leukemia Cutis

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Articles related to Aleukemic Leukemia Cutis:

(show all 25)
idTitleAuthorsYear
1
Prognostic impact of molecular phenotype in patients with recurrent anaplastic glioma treated with prolonged administration of temozolomide. (26138051)
2015
2
Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines. (23676439)
2014
3
Periodic epileptiform discharges in mesial temporal lobe epilepsy with hippocampal sclerosis. (23787169)
2013
4
The BCL11A transcription factor directly activates RAG gene expression and V(D)J recombination. (23438597)
2013
5
Myocardial perfusion spect imaging in dextrocardia: a case report. (24003402)
2013
6
The dominant roles of ICAM-1-encoding gene in DNA vaccination against Japanese encephalitis virus are the activation of dendritic cells and enhancement of cellular immunity. (23411485)
2013
7
Follicular adenoma with extensive extracellular mucin deposition: report on two cases. (23236259)
2012
8
An inverse relationship between KAI1 expression, invasive ability, and MMP-2 expression and activity in bladder cancer cell lines. (20864363)
2012
9
A divergent Sm fold in EDC3 proteins mediates DCP1 binding and P-body targeting. (17923697)
2007
10
Spontaneous cerebrospinal fluid otorrhoea presenting as otitis externa. (17252280)
2007
11
Mammaglobin vs GCDFP-15: an immunohistologic validation survey for sensitivity and specificity. (17145637)
2007
12
Novel compound heterozygous mutations in the PANK2 gene in a Chinese patient with atypical pantothenate kinase-associated neurodegeneration. (15747360)
2005
13
Olanzapine increases slow wave sleep and sleep continuity in SSRI-resistant depressed patients. (15816787)
2005
14
Are 90K/MAC-2BP serum levels correlated with poor prognosis in HCC patients? Preliminary results. (14535594)
2003
15
Habitual snoring and sleep bruxism in a paediatric outpatient population in Hong Kong. (12683350)
2002
16
In vitro effects of some anesthetic drugs on enzymatic activity of human red blood cell glucose 6-phosphate dehydrogenase. (12020046)
2002
17
Structure characterization of human serum proteins in solution and dry state. (11906609)
2002
18
A mouse gene knockout model for juvenile ceroid-lipofuscinosis (Batten disease). (10440905)
1999
19
Serum apolipoprotein E level is not increased in Alzheimer's disease: the Rotterdam study. (9665654)
1998
20
Block by MOPS reveals a conformation change in the CFTR pore produced by ATP hydrolysis. (9357772)
1997
21
Trispiral tomographic staging of KienbAPck's disease. (9195446)
1997
22
Is the activated T helper stimulus able to induce Ig isotype switching in cultured human B cells? (8268132)
1993
23
U-rich sequence-binding proteins (URBPs) interacting with a 20-nucleotide U-rich sequence in the 3' untranslated region of c-fos mRNA may be involved in the first step of c-fos mRNA degradation. (1620106)
1992
24
Effect of finasteride, a 5 alpha-reductase inhibitor on prostate tissue androgens and prostate-specific antigen. (1699965)
1990
25
Left-sided gallbladder:: calculous cholecystitis with situs inversus. (1211989)
1975

Variations for Aleukemic Leukemia Cutis

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Expression for genes affiliated with Aleukemic Leukemia Cutis

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Search GEO for disease gene expression data for Aleukemic Leukemia Cutis.

Pathways for genes affiliated with Aleukemic Leukemia Cutis

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GO Terms for genes affiliated with Aleukemic Leukemia Cutis

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Cellular components related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098978.9ANPEP, CD34, NCAM1

Biological processes related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulation of synaptic plasticityGO:00481679.8NCAM1, RARA
2negative regulation of tumor necrosis factor productionGO:00327209.2CD34, RARA

Sources for Aleukemic Leukemia Cutis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet