MCID: ALK003
MIFTS: 33

Aleukemic Leukemia Cutis malady

Categories: Cancer diseases, Immune diseases

Aliases & Classifications for Aleukemic Leukemia Cutis

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Aliases & Descriptions for Aleukemic Leukemia Cutis:

Name: Aleukemic Leukemia Cutis 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:6003
NCIt42 C4983
UMLS65 C0887846

Summaries for Aleukemic Leukemia Cutis

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MalaCards based summary: Aleukemic Leukemia Cutis is related to leukemia and myelodysplastic syndrome. An important gene associated with Aleukemic Leukemia Cutis is NPM1 (Nucleophosmin (Nucleolar Phosphoprotein B23, Numatrin)), and among its related pathways are LDL Oxidation in Atherogenesis and Transcriptional misregulation in cancer. Affiliated tissues include myeloid, skin and brain, and related mouse phenotypes are tumorigenesis and cardiovascular system.

Related Diseases for Aleukemic Leukemia Cutis

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Diseases related to Aleukemic Leukemia Cutis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 89)
idRelated DiseaseScoreTop Affiliating Genes
1leukemia29.9CD68, FUT4, LYZ, NCAM1, SPN
2myelodysplastic syndrome28.8ANPEP, CD34, FLT3, NPM1, RUNX1
3subleukemic leukemia11.4
4breast cyst10.7MPO, NCAM1
5acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)10.7FLT3, NPM1
6acute myeloblastic leukemia without maturation10.7FLT3, NPM1
7blepharo naso facial syndrome van maldergem type10.7NCAM1, NPM1
8frontal sinus squamous cell carcinoma10.7HAVCR1, LYZ
9distal hereditary motor neuropathy, type ii10.7FLT3, NPM1
10mediastinal mesenchymal tumor10.7CD33, NCAM1
11female reproductive organ cancer10.7MYH11, NCAM1
12inclusion body myositis10.7LYZ, NCAM1
13acute myeloid leukemia and myelodysplastic syndromes related to topoisomerase type 2 inhibitor10.7FLT3, RUNX1
14crescentic glomerulonephritis10.6LYZ, MPO
15alg1-congenital disorder of glycosylation10.6FLT3, RUNX1
16hemosiderosis10.5LYZ, MPO
17acute lymphoblastic leukemia congenital sporadic aniridia10.5ANPEP, MPO
18corticosterone methyloxidase deficiency10.5FLT3, RUNX1
19classic hodgkin lymphoma, mixed cellularity type10.5FLT3, RUNX1
20primary systemic mycosis10.5CD68, NCAM1
21skin granular cell tumor10.5CD68, NCAM1
22rete testis neoplasm10.5CD68, LYZ
23rhabdoid cancer10.4CD68, NCAM1
24ductal carcinoma in situ10.4LYZ, NPM1
25mucinous adenofibroma10.4CD68, LYZ
26pericardial tuberculosis10.4FLT3, MPO, RUNX1
27hematopoietic stem cell transplantation10.4FLT3, NPM1, RUNX1
28primary angle-closure glaucoma10.4CD68, LYZ
29duodenal ulcer10.4CD68, HAVCR1
30burning mouth syndrome10.3CD68, LYZ
31ascending colon cancer10.3LYZ, MPO, SPN
32lymphoblastic leukemia10.3
33cervical incompetence10.2CD68, LYZ, MPO
34acute myeloid leukemia with inv3(p21;q26.2) or t(3;3)(p21;q26.2)10.2FLT3, MPO, MYH11, RUNX1
35pulmonary sclerosing hemangioma10.2CD34, NCAM1
36acute monocytic leukemia10.2
37monocytic leukemia10.2
38myeloid leukemia10.2
39myocardial stunning10.2CD68, LYZ
40intravascular angioleiomyoma10.2CD34, NCAM1
41adult pulmonary langerhans cell histiocytosis10.1ANPEP, FLT3, RUNX1
42nervous system disease10.1CD68, FUT4
43lemierre's syndrome10.1CD68, NCAM1, SPN
44epidural spinal canal angiolipoma10.1CD34, LYZ
45al gazali aziz salem syndrome10.0CD68, LYZ
46cutaneous mastocytosis10.0
47mastocytosis10.0
48adult lymphoma10.0CD34, NCAM1
49malignant pleural mesothelioma10.0CD7, FUT4, NCAM1
50necrotizing fasciitis10.0CD34, CD68

Graphical network of the top 20 diseases related to Aleukemic Leukemia Cutis:



Diseases related to aleukemic leukemia cutis

Symptoms for Aleukemic Leukemia Cutis

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Drugs & Therapeutics for Aleukemic Leukemia Cutis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Aleukemic Leukemia Cutis

Genetic Tests for Aleukemic Leukemia Cutis

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Anatomical Context for Aleukemic Leukemia Cutis

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MalaCards organs/tissues related to Aleukemic Leukemia Cutis:

33
Myeloid, Skin, Brain, Liver, Monocytes, B cells, Bone

Animal Models for Aleukemic Leukemia Cutis or affiliated genes

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MGI Mouse Phenotypes related to Aleukemic Leukemia Cutis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.0CD34, FLT3, LYZ, NPM1, RARA, RUNX1
2MP:00053857.5ANPEP, FUT4, LYZ, MPO, MYH11, NPM1
3MP:00053847.1CD34, FLT3, FUT4, LYZ, MYH11, NCAM1
4MP:00053975.3ANPEP, CD34, CD68, CD7, FLT3, FUT4
5MP:00053875.0ANPEP, CD34, CD68, CD7, FLT3, FUT4

Publications for Aleukemic Leukemia Cutis

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Articles related to Aleukemic Leukemia Cutis:

(show all 25)
idTitleAuthorsYear
1
Pediatric Aleukemic Leukemia Cutis: Report of 3 Cases and Review of the Literature. (25148106)
2014
2
Aleukemic leukemia cutis: an unusual rash in a child. (25035690)
2014
3
Recurrent aleukemic leukemia cutis in a patient with pre-B-cell acute lymphoblastic leukemia. (23733764)
2013
4
Acute myeloid leukemia 7A years after aleukemic leukemia cutis. (24261792)
2013
5
Acute promyelocytic leukemia following aleukemic leukemia cutis harboring NPM/RARA fusion gene. (22573339)
2012
6
Aleukemic leukemia cutis manifesting with disseminated nodular eruptions and a plaque preceding acute monocytic leukemia: a case report. (22187541)
2011
7
Aleukemic leukemia cutis in a child preceding T-cell acute lymphoblastic leukemia. (21895759)
2011
8
Siblings presenting with progressive congenital aleukemic leukemia cutis. (21425444)
2011
9
Aleukemic leukemia cutis with extensive bone involvement. (20708479)
2010
10
Spontaneous regression of aleukemic leukemia cutis harboring a NPM/RARA fusion gene in an infant with cutaneous mastocytosis. (19052694)
2009
11
Aleukemic leukemia cutis preceding acute monocytic leukemia: a case report. (18782972)
2008
12
Aleukemic leukemia cutis. (17456918)
2007
13
Aleukemic leukemia cutis in a patient with Philadelphia chromosome-positive biphenotypic leukemia. (15540904)
2004
14
Guess what. B-cell acute lymphoblastic leukemia with aleukemic leukemia cutis. (11275816)
2001
15
Aleukemic leukemia cutis presenting as benign-appearing exanthema. (11411915)
2001
16
Monocytic aleukemic leukemia cutis. (10565632)
1999
17
Aleukemic leukemia cutis in an adolescent boy. (10084909)
1999
18
Aleukemic leukemia cutis in a patient with acute lymphoblastic leukemia. (9555803)
1998
19
Aleukemic leukemia cutis preceding overt acute myeloid leukemia in myelodysplastic syndrome. (8980276)
1997
20
Lymphocytic aleukemic leukemia cutis. (8912603)
1996
21
Aleukemic leukemia cutis. (2406302)
1990
22
Aleukemic leukemia cutis. (3729513)
1986
23
Aleukemic leukemia cutis. An unusual presentation of acute myelomonocytic leukemia. (2943614)
1986
24
Aleukemic leukemia cutis: juvenile chronic granulocytic leukemia presenting with figurate cutaneous lesions. (6579062)
1983
25
Aleukemic leukemia cutis. (1062968)
1976

Variations for Aleukemic Leukemia Cutis

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Expression for genes affiliated with Aleukemic Leukemia Cutis

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Search GEO for disease gene expression data for Aleukemic Leukemia Cutis.

Pathways for genes affiliated with Aleukemic Leukemia Cutis

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GO Terms for genes affiliated with Aleukemic Leukemia Cutis

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Cellular components related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098978.9ANPEP, CD34, NCAM1

Biological processes related to Aleukemic Leukemia Cutis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulation of synaptic plasticityGO:00481679.8NCAM1, RARA
2negative regulation of tumor necrosis factor productionGO:00327209.2CD34, RARA

Sources for Aleukemic Leukemia Cutis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet