MCID: ALT002
MIFTS: 33

Aleutian Mink Disease malady

Categories: Infectious diseases

Aliases & Classifications for Aleutian Mink Disease

Aliases & Descriptions for Aleutian Mink Disease:

Name: Aleutian Mink Disease 12 42 14 69
Aleutian Disease 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2934
MeSH 42 D000453
SNOMED-CT 64 62251004
UMLS 69 C0002016

Summaries for Aleutian Mink Disease

Disease Ontology : 12 A viral infectious disease that results_in inflammatory destruction located in blood vessels of minks and rarely in humans, which has material basis in Aleutian mink disease virus. The infection has symptom weight loss, has symptom hepatomegaly, has symptom enlarged spleen, and has symptom anemia.

MalaCards based summary : Aleutian Mink Disease, also known as aleutian disease, is related to infundibulocystic basal cell carcinoma and generalized atherosclerosis, and has symptoms including weight loss, hepatomegaly and enlarged spleen. An important gene associated with Aleutian Mink Disease is MMP11 (Matrix Metallopeptidase 11), and among its related pathways/superpathways are TNFR1 Pathway and TRAF Pathway. Affiliated tissues include spleen, kidney and testes.

Related Diseases for Aleutian Mink Disease

Diseases related to Aleutian Mink Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
id Related Disease Score Top Affiliating Genes
1 infundibulocystic basal cell carcinoma 10.2 CD40LG PHYH
2 generalized atherosclerosis 10.2 CD40LG IL6
3 temporal arteritis 10.2 ALB PHYH
4 bile duct adenocarcinoma 10.2 ALB CD40LG
5 colloid adenoma 10.2 ALB CD40LG
6 shoulder impingement syndrome 10.2 ALB IL6
7 estrogen excess 10.2 ALB CD40LG
8 freiberg's disease 10.2 ALB CD40LG
9 striatonigral degeneration 10.1 ALB CD40LG
10 human immunodeficiency virus infectious disease 10.1 CD40LG IL6
11 dyskeratosis congenita 10.1 ALB CD40LG
12 hereditary alpha tryptasemia syndrome 10.1 ALB CD40LG IL6
13 glucosephosphate dehydrogenase deficiency 10.1 ALB IL6
14 plummer's disease 10.1 ALB CD40LG IL6
15 early yaws 10.1 ALB CD40LG IL6
16 papilledema 10.1 IL6 TTR
17 depressed scar 10.1 ALB CD40LG IL6
18 pneumonia 10.1
19 anterior foramen magnum meningioma 10.1 ALB CD40LG IL6
20 phaeochromocytoma 10.1 ALB TTR
21 bacterial meningitis 10.1 ALB CD40LG IL6
22 nephropathy with pretibial epidermolysis bullosa and deafness 10.1 ALB CD40LG IL6
23 foodborne botulism 10.1 ALB CD40LG IL6
24 pulmonary eosinophilia 10.1 ALB CD40LG IL6
25 acute chest syndrome 10.1 ALB CD40LG IL6
26 ehlers-danlos syndrome, periodontal type 1 10.1 ALB TTR
27 calcinosis 10.1 ALB CD40LG IL6
28 coronary artery dissection, spontaneous 10.1 ALB CD40LG
29 membranoproliferative glomerulonephritis 10.1 ALB CD40LG IL6
30 labyrinthine bilateral reactive loss 10.0 ALB IL6
31 childhood malignant hemangiopericytoma 10.0 ALB CD40LG IL6
32 trachoma 10.0 ALB CD40LG NGFR
33 male genital organ stricture 10.0 ALB TTR
34 glomangiosarcoma 10.0 CD40LG PHYH
35 female infertility of uterine origin 10.0 ALB TTR
36 cataract 10.0 ALB TTR
37 chronic inflammatory demyelinating polyneuritis 10.0 ALB CD40LG
38 bladder sarcoma 10.0 ALB IL6 TTR
39 congenital nonspherocytic hemolytic anemia 10.0 ALB TTR
40 paranasal sinus sarcoma 10.0 ALB IL6 TTR
41 central nervous system leiomyoma 10.0 ALB IL6 TTR
42 spastic entropion 10.0 ALB CD40LG TTR
43 glomerulonephritis 9.9
44 immune-complex glomerulonephritis 9.9
45 uterine ligament serous adenocarcinoma 9.9 ALB CD40LG TTR
46 chronic myocardial ischemia 9.9 ALB IL6 TTR
47 connective tissue disease 9.9
48 peritonitis 9.9
49 meningoencephalitis 9.9
50 interstitial nephritis 9.9

Graphical network of the top 20 diseases related to Aleutian Mink Disease:



Diseases related to Aleutian Mink Disease

Symptoms & Phenotypes for Aleutian Mink Disease

Symptoms:

12
  • weight loss
  • hepatomegaly
  • enlarged spleen
  • anemia

UMLS symptoms related to Aleutian Mink Disease:


lameness, animal

Drugs & Therapeutics for Aleutian Mink Disease

Search Clinical Trials , NIH Clinical Center for Aleutian Mink Disease

Cochrane evidence based reviews: aleutian mink disease

Genetic Tests for Aleutian Mink Disease

Anatomical Context for Aleutian Mink Disease

MalaCards organs/tissues related to Aleutian Mink Disease:

39
Spleen, Kidney, Testes, B Cells, Lymph Node, Brain

The Foundational Model of Anatomy Ontology organs/tissues related to Aleutian Mink Disease:

18
Blood Vessels Of Minks

Publications for Aleutian Mink Disease

Articles related to Aleutian Mink Disease:

(show top 50) (show all 101)
id Title Authors Year
1
Accuracy of enzyme-linked immunosorbent assays for quantification of antibodies against Aleutian mink disease virus. ( 27283885 )
2016
2
Progression of experimental chronic Aleutian mink disease virus infection. ( 27250118 )
2016
3
Genetic characterization of the complete genome of an Aleutian mink disease virus isolated in north China. ( 27007772 )
2016
4
A fast and robust method for whole genome sequencing of the Aleutian Mink Disease Virus (AMDV) genome. ( 27060623 )
2016
5
Identification of a novel Aleutian mink disease virus B-cell epitope using a monoclonal antibody against VP2 protein. ( 27354304 )
2016
6
Development of an Enzyme-Linked Immunosorbent Assay Based on Fusion VP2332-452 Antigen for Detecting Antibodies against Aleutian Mink Disease Virus. ( 26582828 )
2016
7
Development of a Peptide ELISA for the Diagnosis of Aleutian Mink Disease. ( 27802320 )
2016
8
High molecular polymorphism of the hypervariable region in the VP2 gene of Aleutian mink disease virus. ( 27928914 )
2016
9
Driving forces behind the evolution of the Aleutian mink disease parvovirus in the context of intensive farming. ( 27774297 )
2016
10
Aleutian mink disease virus in free-ranging mustelids in Finland - a cross-sectional epidemiologic and phylogenetic study. ( 25667324 )
2015
11
Molecular epidemiology of Aleutian mink disease virus (AMDV) in Estonia, and a global phylogeny of AMDV. ( 25616049 )
2015
12
Detection of Aleutian mink disease virus DNA and antiviral antibodies in American mink (Neovison vison) 10 days postinoculation. ( 25862712 )
2015
13
PREVALENCE OF ANTIBODY TO ALEUTIAN MINK DISEASE VIRUS IN EUROPEAN MINK (MUSTELA LUTREOLA) AND AMERICAN MINK (NEOVISON VISON) IN SPAIN. ( 26528576 )
2015
14
Aleutian mink disease virus in striped skunks (mephitis mephitis): evidence for cross-species spillover. ( 25647590 )
2015
15
Aleutian mink disease virus in free-ranging mink from sweden. ( 25822750 )
2015
16
Molecular epidemiology of Aleutian mink disease virus in China. ( 24561116 )
2014
17
Inactivation of Aleutian mink disease virus through high temperature exposure in vitro and under field-based composting conditions. ( 25139658 )
2014
18
Molecular characterization of the small nonstructural proteins of parvovirus Aleutian mink disease virus (AMDV) during infection. ( 24606679 )
2014
19
Diagnosing Aleutian mink disease infection by a new fully automated ELISA or by counter current immunoelectrophoresis: a comparison of sensitivity and specificity. ( 24462658 )
2014
20
Validation of an automated ELISA system for detection of antibodies to Aleutian mink disease virus using blood samples collected in filter paper strips. ( 25103400 )
2014
21
Testing for aleutian mink disease virus in the river otter (Lontra canadensis) in sympatry with infected American mink (Neovison vison). ( 24807350 )
2014
22
Monitoring chronic infection with a field strain of Aleutian mink disease virus. ( 24389253 )
2014
23
Application of real-time PCR to detect Aleutian Mink Disease Virus on environmental farm sources. ( 25183237 )
2014
24
Aleutian mink disease virus in furbearing mammals in Nova Scotia, Canada. ( 23394546 )
2013
25
Evaluation of two enzyme-linked immunosorbent assays for serodiagnosis of Aleutian mink disease virus infection in mink. ( 24274663 )
2013
26
Genetic characterization of Aleutian mink disease viruses isolated in China. ( 22415541 )
2012
27
Prevalence of the Aleutian mink disease virus infection in Nova Scotia, Canada. ( 22497690 )
2012
28
Phylogenetic analysis of the VP2 gene of Aleutian mink disease parvoviruses isolated from 2009 to 2011 in China. ( 22415542 )
2012
29
High prevalence of Aleutian mink disease virus in free-ranging mink on a remote Danish island. ( 22493130 )
2012
30
Implementation and validation of a sensitive PCR detection method in the eradication campaign against Aleutian mink disease virus. ( 20951744 )
2011
31
Diversity and stability of Aleutian mink disease virus during bottleneck transitions resulting from eradication in domestic mink in Denmark. ( 21112164 )
2011
32
A survey of Aleutian mink disease virus infection of feral American mink in Nova Scotia. ( 20357945 )
2010
33
Neuropathologic features of Aleutian disease in farmed mink in Ireland and molecular characterization of Aleutian mink disease virus detected in brain tissues. ( 20093694 )
2010
34
The capsid proteins of Aleutian mink disease virus activate caspases and are specifically cleaved during infection. ( 20042496 )
2010
35
Development and evaluation of an enzyme-linked immunosorbent assay based on recombinant VP2 capsids for the detection of antibodies to Aleutian mink disease virus. ( 19641102 )
2009
36
Molecular epidemiology of Aleutian mink disease virus in Finland. ( 18799272 )
2009
37
Aleutian mink disease virus and humans. ( 19961696 )
2009
38
The abundant R2 mRNA generated by aleutian mink disease parvovirus is tricistronic, encoding NS2, VP1, and VP2. ( 17428872 )
2007
39
The transcription profile of Aleutian mink disease virus in CRFK cells is generated by alternative processing of pre-mRNAs produced from a single promoter. ( 16378968 )
2006
40
DNA vaccination with the Aleutian mink disease virus NS1 gene confers partial protection against disease. ( 15652664 )
2005
41
Persistent viral shedding during asymptomatic Aleutian mink disease parvoviral infection in a ferret. ( 16475522 )
2005
42
Pathogenesis of aleutian mink disease parvovirus and similarities to b19 infection. ( 16316395 )
2005
43
Antibodies to Aleutian mink disease parvovirus in free-ranging European mink (Mustela lutreola) and other small carnivores from southwestern France. ( 15465705 )
2004
44
Cytokine profiles in adult mink infected with Aleutian mink disease parvovirus. ( 12805443 )
2003
45
Caspase cleavage of the nonstructural protein NS1 mediates replication of Aleutian mink disease parvovirus. ( 12692232 )
2003
46
Caspase activation is required for permissive replication of Aleutian mink disease parvovirus in vitro. ( 11878925 )
2002
47
Identification of aleutian mink disease parvovirus capsid sequences mediating antibody-dependent enhancement of infection, virus neutralization, and immune complex formation. ( 11602751 )
2001
48
Aleutian mink disease parvovirus in wild riparian carnivores in Spain. ( 11272488 )
2001
49
Nonsuppurative meningoencephalitis associated with Aleutian mink disease parvovirus infection in ranch mink. ( 10730948 )
2000
50
Replication of Aleutian mink disease parvovirus in mink lymph node histocultures. ( 10644831 )
2000

Variations for Aleutian Mink Disease

Expression for Aleutian Mink Disease

Search GEO for disease gene expression data for Aleutian Mink Disease.

Pathways for Aleutian Mink Disease

GO Terms for Aleutian Mink Disease

Cellular components related to Aleutian Mink Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.63 ALB CD40LG DEFB4A DEFB4B IL6 TTR
2 extracellular region GO:0005576 9.23 ALB CD40LG DEFB4A DEFB4B IL6 MMP11
3 Golgi lumen GO:0005796 9.13 DEFB4A DEFB4B MMP11

Biological processes related to Aleutian Mink Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.67 ALB CD40LG IL6 NGFR
2 aging GO:0007568 9.5 CASP7 DMD IL6
3 immune response GO:0006955 9.35 CD40LG DEFB4A DEFB4B IL6 NGFR
4 defense response to Gram-positive bacterium GO:0050830 9.33 DEFB4A DEFB4B IL6
5 muscle cell cellular homeostasis GO:0046716 9.26 DMD IL6
6 defense response to Gram-negative bacterium GO:0050829 8.8 DEFB4A DEFB4B IL6

Molecular functions related to Aleutian Mink Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cysteine-type endopeptidase activity involved in execution phase of apoptosis GO:0097200 8.96 CASP10 CASP7
2 CCR6 chemokine receptor binding GO:0031731 8.62 DEFB4A DEFB4B

Sources for Aleutian Mink Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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