ABPA
MCID: ALL008
MIFTS: 66

Allergic Bronchopulmonary Aspergillosis (ABPA) malady

Rare diseases, Respiratory diseases, Immune diseases, Infectious diseases categories

Summaries for Allergic Bronchopulmonary Aspergillosis

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9Disease Ontology, 66Wikipedia, 48OMIM, 34MalaCards
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Disease Ontology:9 An aspergillosis that involves an allergic reaction due to the spores of aspergillus moulds (a. fumigatus), which colonizes the mucus in the airways causing inflammation. the disease has symptom cough, has symptom wheezing and has symptom fever.

MalaCards: Allergic Bronchopulmonary Aspergillosis, also known as aspergillosis, allergic bronchopulmonary, is related to aspergillosis and cystic fibrosis, and has symptoms including fever, wheezing and cough. An important gene associated with Allergic Bronchopulmonary Aspergillosis is SFTPA2 (surfactant protein A2), and among its related pathways are IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types and FOXA1 transcription factor network. The compounds betaseron and omalizumab have been mentioned in the context of this disorder. Affiliated tissues include lung, colon and testes, and related mouse phenotypes are digestive/alimentary and liver/biliary system.

Wikipedia:66 Allergic bronchopulmonary aspergillosis (ABPA) is a condition characterised by an exaggerated response... more...

Description from OMIM:48 103920

Aliases & Classifications for Allergic Bronchopulmonary Aspergillosis

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Sources:
9Disease Ontology, 44NIH Rare Diseases, 46Novoseek, 50Orphanet, 48OMIM, 63UMLS, 28ICD9CM, 59SNOMED-CT, 36MeSH, 41NCIt, 37MESH via Orphanet, 27ICD10 via Orphanet, 60SNOMED-CT via Orphanet, 64UMLS via Orphanet
See all sources

Classifications:



Characteristics (Orphanet epidemiological data):

50
allergic bronchopulmonary aspergillosis:
Inheritance: Sporadic; Age of onset: Childhood


Aliases & Descriptions:

allergic bronchopulmonary aspergillosis 9 44 50 48
aspergillosis, allergic bronchopulmonary 44 63
hinson-pepys disease 44 50
abpa 44 50
aspergillosis allergic bronchopulmonary 46
allergic bronchopulmonary mycosis 44
pulmonary aspergillus disease 9
allergic aspergillosis 50


External Ids:

Disease Ontology9 DOID:13166
ICD9CM28 518.6
OMIM48 103920
MeSH36 D001229
NCIt41 C84547
SNOMED-CT59 37981002
MESH via Orphanet37 D001229
ICD10 via Orphanet27 B44.1
SNOMED-CT via Orphanet60 37981002
UMLS via Orphanet64 C0004031

Related Diseases for Allergic Bronchopulmonary Aspergillosis

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Allergic Bronchopulmonary Aspergillosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 133)
idRelated DiseaseScoreTop Affiliating Genes
1aspergillosis32.5MBL2, IFNG, SFTPA2, SFTPD
2cystic fibrosis31.9IGES, SFTPD, CFTR, CCL17, CCL22, MBL2
3asthma31.7IL5, IL4, IGHE, IGES
4sinusitis31.4IGES, IGHE, CFTR, IL5
5bronchiectasis31.1IGES, IGHE, CFTR, MBL2
6rhinitis30.9IGES, IGHE, IL4, IL5
7pulmonary tuberculosis30.8HLA-DRB1, HLA-DQB1, IGES, IFNG, IL4, MBL2
8atopic dermatitis30.8CCL17, CCL22, IL4
9allergic rhinitis30.8IL5, IL4, IGHE
10tuberculosis30.7IGES, HLA-DQB1, HLA-DRB1, SFTPD, CCR4, IFNG
11pneumonia30.7MBL2, IL10, IL5, CCL22, CCL17, TXN
12atopy30.7IL10, IL5, IL4, IFNG, CCL22, CCL17
13eosinophilia30.6IFNG, CCR4, CCL17, IGHE, IGES, IL4
14extrinsic allergic alveolitis30.6IGHE, SFTPD
15dermatitis30.5IL5, IL4, IFNG, CCL22, CCR4, CCL17
16eosinophilic pneumonia30.5IGHE, CCL17, CCL22, IL5
17bronchitis30.5IGHE, CFTR, IL5
18pulmonary eosinophilia30.5IL5, IL4, SFTPD, IGHE
19respiratory failure30.5IGES, IGHE, SFTPD, CFTR, CCL17
20sarcoidosis30.3HLA-DQB1, HLA-DRB1, SFTPD, TXN, CCR4, IFNG
21arthritis30.3HLA-DRB1, TXN, IFNG, IL4, IL10
22rheumatoid arthritis30.0HLA-DQB1, HLA-DRB1, SFTPD, CFTR, TXN, CCR4
23pneumothorax10.5
24middle lobe syndrome10.4
25churg-strauss syndrome10.4
26endocarditis10.4
27antiphospholipid syndrome10.3
28chronic eosinophilic pneumonia10.3
29lipid pneumonia10.3
30cerebritis10.3
31cough variant asthma10.3
32cataract10.3
33hypertension10.3
34infective endocarditis10.3
35mycetoma10.3
36spontaneous pneumothorax10.3
37pulmonary function10.3
38interstitial lung disease10.1SFTPD
39conjunctivitis10.1IGES, IGHE
40eczema herpeticum10.1IGHE
41eosinophilic fasciitis10.1IL5
42eosinophilia-myalgia syndrome10.1IL5
43keratoconjunctivitis10.1IL5
44rheumatic congestive heart failure10.1MBL2
45cryptosporidiosis10.1MBL2
46keratoconjunctivitis sicca10.1CFTR
47immunoglobulin g deficiency10.1IGHE, MBL2
48leprosy10.1HLA-DRB1
49eosinophilic gastroenteritis10.1IGHE, IL5
50adult t-cell leukemia10.1TXN

Graphical network of the top 20 diseases related to Allergic Bronchopulmonary Aspergillosis:



Diseases related to allergic bronchopulmonary aspergillosis

Symptoms for Allergic Bronchopulmonary Aspergillosis

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Sources:
48OMIM, 9Disease Ontology
See all sources

Symptoms by clinical synopsis from OMIM:

103920

Clinical features from OMIM:

103920

Symptoms:

9 (show all 15)
  • fever
  • wheezing
  • cough
  • pulmonary hypertension
  • hemoptysis
  • emphysema
  • anomalies of the immunitary system
  • eosinophils anomalies/hypereosinophilia
  • ground-glass/reticular/alveolar/interstitial lung/pulmonary opacity
  • bronchial dilation/dilatation/bronchiectasia
  • weight loss/loss of appetite/break in weight curve/general health alteration
  • fever/chilling
  • abnormal fingernails
  • respiratory distress/dyspnea/respiratory failure/lung volume reduction
  • asthma/bronchospasm

Drugs & Therapeutics for Allergic Bronchopulmonary Aspergillosis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Allergic Bronchopulmonary Aspergillosis

Drug clinical trials:

Search ClinicalTrials for Allergic Bronchopulmonary Aspergillosis

Search NIH Clinical Center for Allergic Bronchopulmonary Aspergillosis

Search CenterWatch for Allergic Bronchopulmonary Aspergillosis

Genetic Tests for Allergic Bronchopulmonary Aspergillosis

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Anatomical Context for Allergic Bronchopulmonary Aspergillosis

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Sources:
34MalaCards
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MalaCards organs/tissues related to Allergic Bronchopulmonary Aspergillosis:

34
Lung, Colon, Testes, T cells, Skin, B cells

Animal Models for Allergic Bronchopulmonary Aspergillosis or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Allergic Bronchopulmonary Aspergillosis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.5CFTR, IFNG, IL4, IL5, IL10, HLA-DQB1
2MP:00053708.4HLA-DQB1, CFTR, IFNG, IL4, IL5, IL10
3MP:00053887.7HLA-DQB1, SFTPD, CFTR, CCR4, IFNG, IL4
4MP:00053767.2IGHE, HLA-DQB1, SFTPD, CFTR, IFNG, IL4
5MP:00053976.8MBL2, IGHE, HLA-DQB1, SFTPD, CFTR, CCL17
6MP:00053876.7CFTR, SFTPD, HLA-DQB1, IGHE, CCL17, CCR4

Publications for Allergic Bronchopulmonary Aspergillosis

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Sources:
53PubMed
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Articles related to Allergic Bronchopulmonary Aspergillosis:

(show top 50)    (show all 497)
idTitleAuthorsYear
1
Anti-IgE therapy for allergic bronchopulmonary aspergillosis. (24291616)
2013
2
Allergic bronchopulmonary aspergillosis. (22640845)
2012
3
Clinical features of allergic bronchopulmonary aspergillosis in Korea. (22950037)
2012
4
Serologic allergic bronchopulmonary aspergillosis (ABPA-S): long-term outcomes. (22445696)
2012
5
Blood basophils from cystic fibrosis patients with allergic bronchopulmonary aspergillosis are primed and hyper-responsive to stimulation by aspergillus allergens. (22608296)
2012
6
A rare cause of acute respiratory failure--allergic bronchopulmonary aspergillosis. (20028466)
2011
7
Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis among asthma patients in eastern India. (21661466)
2010
8
Aerosolized amphotericin for the treatment of allergic bronchopulmonary aspergillosis. (20658484)
2010
9
An alternate method of classifying allergic bronchopulmonary aspergillosis based on high-attenuation mucus. (21179536)
2010
10
Codiagnosis of allergic bronchopulmonary aspergillosis and sarcoid in a severe asthmatic patient. (21130394)
2010
11
Allergic bronchopulmonary aspergillosis: Indian perspective. (19445441)
2009
12
Voriconazole in the treatment of allergic bronchopulmonary aspergillosis in cystic fibrosis. (19284017)
2009
13
Multiple bronchoceles in a non-asthmatic patient with allergic bronchopulmonary aspergillosis. (18846804)
2008
14
Frequency of familial occurrence in 164 patients with allergic bronchopulmonary aspergillosis. (18939723)
2008
15
Successful treatment of allergic bronchopulmonary aspergillosis with recombinant anti-IgE antibody. (17329558)
2007
16
Using rare diseases as models for biobehavioral research: allergic bronchopulmonary aspergillosis. (17883921)
2007
17
Case quiz. Thoracic CT illustrating hyperdense bronchial mucous plugging: allergic bronchopulmonary aspergillosis. (12890264)
2003
18
Antifungal therapy for allergic bronchopulmonary aspergillosis. (12743553)
2003
19
Aspergillus antigens associated with allergic bronchopulmonary aspergillosis. (12456371)
2003
20
Azoles for allergic bronchopulmonary aspergillosis associated with asthma. (12917898)
2003
21
Allergic bronchopulmonary aspergillosis, allergic fungal sinusitis, and hypersensitivity pneumonitis. (11577554)
2002
22
Allergic bronchopulmonary aspergillosis. (10893349)
2000
23
Therapy of allergic bronchopulmonary aspergillosis. (15597668)
2000
24
Increased sensitivity to IL-4 in patients with allergic bronchopulmonary aspergillosis. (11146389)
2000
25
Accuracy of CT in the diagnosis of allergic bronchopulmonary aspergillosis in asthmatic patients. (10511153)
1999
26
Specific IgG subclass antibody pattern to Aspergillus fumigatus in patients with cystic fibrosis with allergic bronchopulmonary aspergillosis (ABPA). (10343631)
1999
27
The role of bronchial biopsy and washing in the diagnosis of allergic bronchopulmonary aspergillosis. (9688180)
1998
28
Recurrence of allergic bronchopulmonary aspergillosis in the posttransplant lungs of a cystic fibrosis patient. (9228393)
1997
29
The use of bronchofiberscopy for diagnosis of allergic bronchopulmonary aspergillosis. (9475240)
1997
30
Prevalence of allergic bronchopulmonary aspergillosis and atopy in adult patients with cystic fibrosis. (8769507)
1996
31
Immunohistochemical detection of GM-CSF, IL-4 and IL-5 in a murine model of allergic bronchopulmonary aspergillosis. (8732244)
1996
32
Successful treatment of fungus ball in a patient with allergic bronchopulmonary aspergillosis: continuous percutaneous instillation of antifungal agents into the cavity. (8915703)
1996
33
T cell subsets, epitope mapping, and HLA-restriction in patients with allergic bronchopulmonary aspergillosis. (8636413)
1996
34
Allergic bronchopulmonary aspergillosis: an unusual complication of bronchial asthma. (8920604)
1995
35
Problems with skin testing in patients with allergic bronchopulmonary aspergillosis. (8603286)
1995
36
Allergic bronchopulmonary aspergillosis: a case report. (7674424)
1995
37
Management of allergic bronchopulmonary aspergillosis. (8029520)
1994
38
Diagnosis and management of allergic bronchopulmonary aspergillosis. (7721084)
1994
39
Serum anti-Aspergillus fumigatus antibodies by immunoblot and ELISA in cystic fibrosis with allergic bronchopulmonary aspergillosis. (8182235)
1994
40
Pneumothorax and bronchopleural fistula during treatment of allergic bronchopulmonary aspergillosis. (8367756)
1993
41
Concanavalin A-nonbinding Aspergillus fumigatus antigen: a major immunogen in allergic bronchopulmonary aspergillosis. (1583388)
1992
42
A murine model of allergic bronchopulmonary aspergillosis with elevated eosinophils and IgE. (1602128)
1992
43
Adjunctive therapy of allergic bronchopulmonary aspergillosis with itraconazole. (1653680)
1991
44
Pathologic features of allergic bronchopulmonary aspergillosis. (3344888)
1988
45
Allergic bronchopulmonary aspergillosis in a young child: diagnostic confirmation by serum IgE and IgG indices. (3954164)
1986
46
Environmental aerobiological studies in allergic bronchopulmonary aspergillosis. (6711771)
1984
47
Varying presentations of allergic bronchopulmonary aspergillosis. (6365793)
1984
48
Allergic bronchopulmonary aspergillosis: reactivity of IgE and IgG antibodies with antigenic components of Aspergillus fumigatus (IgE/IgG antigen complexes). (6605984)
1983
49
Mould counts and exacerbations of allergic bronchopulmonary aspergillosis. (6342846)
1983
50
Allergic bronchopulmonary aspergillosis in cystic fibrosis. (7138421)
1982

Variations for Allergic Bronchopulmonary Aspergillosis

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Expression for genes affiliated with Allergic Bronchopulmonary Aspergillosis

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Allergic Bronchopulmonary Aspergillosis

Search GEO for disease gene expression data for Allergic Bronchopulmonary Aspergillosis.

Pathways for genes affiliated with Allergic Bronchopulmonary Aspergillosis

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Sources:
51PathCards, 55R&D Systems, 39NCBI BioSystems Database, 31KEGG, 61Thomson Reuters, 56Reactome, 5Cell Signaling Technology, 54QIAGEN
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Pathways related to Allergic Bronchopulmonary Aspergillosis according to GeneCards/GeneDecks:

(show all 34)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.9IL5, IL4
2
Show member pathways
FOXA transcription factor networks39
9.8SFTPA2, SFTPA1, SFTPD
39.7SFTPA2, SFTPA1, IL10
49.6HLA-DRB1, IL5, IL4
59.5IFNG, IL5, IL4
69.5IL5, IFNG, IL4
7
Show member pathways
Calcium signaling in the CD4+ TCR pathway39
9.5IL4, IL5, IFNG
8
Show member pathways
Immune response IL 12 induced IFN gamma production61
9.5IFNG, IL4, HLA-DRB1
9
Show member pathways
9.4CCL17, CCL22, CCR4
109.4HLA-DRB1, IFNG, HLA-DQB1
119.3IL10, IL4, TXN
12
Show member pathways
Immune response T cell receptor signaling pathway61
Immune response CD28 signaling61
Immune response ICOS pathway in T helper cell61
9.3HLA-DQB1, HLA-DRB1, IGHE
139.2HLA-DQB1, HLA-DRB1, IL10, MBL2
14
Show member pathways
Type III interferon signaling39
9.1IL4, IL10, IL5, IFNG
15
Show member pathways
BCR signaling pathway39
TCR Signaling Pathway39
9.1IFNG, IL4, IL10, IL5
169.1IFNG, IL10, IL5, IL4
179.1IL10, IFNG, IL5, IL4
18
Show member pathways
9.1IL4, IFNG, HLA-DRB1, HLA-DQB1
19
Show member pathways
9.1IL5, IFNG, HLA-DRB1, HLA-DQB1
20
Show member pathways
Transcription NF kB signaling pathway61
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response61
9.0IL4, IFNG, CFTR, SFTPA1, SFTPD
219.0IFNG, HLA-DQB1, HLA-DRB1, IL10
22
Show member pathways
9.0HLA-DQB1, IL10, IFNG, HLA-DRB1
239.0HLA-DQB1, HLA-DRB1, IFNG, IL10
248.9MBL2, SFTPA2, SFTPA1, SFTPD, HLA-DQB1, HLA-DRB1
258.8IGHE, CCL17, IL4, IL5, IL10
268.8IL10, HLA-DRB1, IFNG, IL5, IL4
27
Show member pathways
8.7IL5, IL10, IL4, IFNG, CCL22, CCL17
28
Show member pathways
8.5CCL17, CCR4, IL5, IL4, CCL22, IL10
29
Show member pathways
8.5IL5, CCL22, IL10, CCL17, CCR4, IL4
30
Show member pathways
8.5IL10, CCL17, CCR4, CCL22, IL4, IL5
31
Show member pathways
8.5HLA-DQB1, IL10, IL5, IFNG, HLA-DRB1, IL4
32
Show member pathways
8.5HLA-DQB1, HLA-DRB1, IL4, IL5, IFNG, IL10
33
Show member pathways
8.3SRSF7, HLA-DRB1, IL4, HLA-DQB1, IFNG
34
Show member pathways
8.1IL10, CCR4, CCL22, IFNG, IL4, IL5

Compounds for genes affiliated with Allergic Bronchopulmonary Aspergillosis

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Sources:
46Novoseek, 12DrugBank, 30IUPHAR, 62Tocris Bioscience, 52PharmGKB, 3BitterDB, 25HMDB
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Compounds related to Allergic Bronchopulmonary Aspergillosis according to GeneCards/GeneDecks:

(show top 50)    (show all 132)
idCompoundScoreTop Affiliating Genes
1betaseron469.8IL10, IFNG, IL4
2omalizumab46 1210.8IL4, IL5, IGHE
3interferon gamma469.8IFNG, IL4, IL10
4alpha-galactosylceramide469.7IL4, IL10, IFNG
5ovomucoid469.7IL5, IL4, IGHE
6nedocromil sodium469.6IGHE, IL4, IL5
7anti-fungal469.6MBL2, IL5, IFNG, SFTPD
8polymyxin b469.6IL4, IL10, MBL2, IFNG
9il-12469.5IL10, IFNG, IL4, IL5
10gm-csf46 3010.5IL4, IFNG, IL10, IL5
11tuberculin469.5MBL2, IL10, IFNG
12polyinosinic-polycytidylic acid469.5IL5, IFNG, IL4, IL10
13rolipram46 62 3011.5IFNG, IL4, IL5, IL10
14ribavirin46 52 1211.5MBL2, IL10, IL4, IFNG
15praziquantel46 1210.4IL10, IL5, IL4, IGHE
16montelukast46 52 30 1212.4IGHE, IL10, IL5, IL4
17neopterin469.4MBL2, IL4, IFNG, IL10
18il 10469.4IL10, IL5, IL4, CCL17, IFNG
19fluticasone propionate46 52 62 1212.4IGHE, IFNG, IL5, IL4
20con a469.3IFNG, IL4, IL5, IL10, MBL2
21gold sodium thiomalate469.3IFNG, TXN, HLA-DRB1
22glatiramer acetate46 1210.2HLA-DRB1, IL4, IL5, IFNG, IL10
23infliximab46 52 1211.2IFNG, IL4, IL10, IGHE
24budesonide46 52 1211.2SFTPD, IL4, IGHE, IL5, IFNG
25methacholine46 52 1211.2IL5, CCL22, IGES, IL4, IGHE
26tacrolimus46 52 1211.1CCL22, IL10, IL4, IL5, CCL17, IFNG
2715-deoxy-delta-12,14-prostaglandin j2469.1IL4, IL10, IFNG, TXN
28ccl346 3010.1IL10, CCL22, IFNG, CCL17, CCR4
29ivig469.0IGHE, IFNG, IL4, IL10, IL5
30hydrocortisone46 3 62 1212.0IFNG, IL4, IL10, IL5, IGHE
31carbohydrates469.0MBL2, IGHE, TXN, CFTR, SFTPD
32sb 20358046 629.9IL10, IL4, IFNG, CCL22, IL5
33pge2468.9CFTR, IL10, CCL22, IL5, IL4, IFNG
34paraffin468.7IL4, IL5, IL10, MBL2, CFTR, CCR4
35thyroxine46 259.7IL4, TXN, IL5, IL10, MBL2, IGHE
36vitamin d468.6IGHE, TXN, MBL2, IL10, IL5, CFTR
37glutamine468.6SFTPD, IGHE, CFTR, TXN, IL5, HLA-DQB1
38indomethacin46 30 62 1211.4IGHE, CFTR, IFNG, IL5, IL4
39adenylate468.4TXN, CCL22, IL5, IL4, CFTR, IGHE
40aspartate468.3IGHE, HLA-DQB1, TXN, IL10, CFTR, MBL2
41rantes468.3IL10, MBL2, IFNG, CCL22, CCR4, IL5
42prednisolone46 30 1210.2IGHE, SFTPD, IL5, IL10, MBL2, IFNG
43histamine46 30 2510.1IL4, IL10, IFNG, CCL22, IL5, SFTPD
44vegf468.1MBL2, IFNG, TXN, IGHE, IL4, IL10
45tarc468.0IL5, CCL17, IGHE, CCR4, CCL22, IFNG
46cycloheximide468.0IFNG, IL5, IGHE, TXN, IL4, IL10
47allergens467.8IFNG, CCL17, IL10, IL5, IGES, IGHE
48arginine467.5IL4, IL5, IGHE, HLA-DRB1, TXN, SRSF7
49cyclosporin a46 30 629.4IFNG, CCL22, IL10, CCL17, TXN, CFTR
50dexamethasone46 52 30 1210.3MBL2, IFNG, IGHE, SFTPD, IL10, IL5

GO Terms for genes affiliated with Allergic Bronchopulmonary Aspergillosis

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Sources:
17Gene Ontology
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Cellular components related to Allergic Bronchopulmonary Aspergillosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1MHC class II protein complexGO:0426139.8HLA-DRB1, HLA-DQB1
2collagenGO:0055819.5SFTPA1, MBL2, SFTPA2, SFTPD
3external side of plasma membraneGO:0098978.5IL4, IFNG, CCR4, HLA-DRB1
4extracellular regionGO:0055767.9MBL2, CCL22, IL5, IFNG, IGHE, SFTPD
5extracellular spaceGO:0056157.9IL10, IL5, IL4, IFNG, CCL22, CCL17

Biological processes related to Allergic Bronchopulmonary Aspergillosis according to GeneCards/GeneDecks:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1regulation of isotype switchingGO:04519110.1IL4, IL10
2type 2 immune responseGO:04209210.1IL10, IL4
3positive regulation of isotype switching to IgG isotypesGO:04830410.0IL4, IFNG
4immunoglobulin production involved in immunoglobulin mediated immune responseGO:00238110.0HLA-DRB1, HLA-DQB1
5positive regulation of chemokine biosynthetic processGO:04508010.0IFNG, IL4
6humoral immune response mediated by circulating immunoglobulinGO:00245510.0HLA-DRB1, HLA-DQB1
7negative regulation of nitric oxide biosynthetic processGO:0450199.9IL4, IL10
8respiratory gaseous exchangeGO:0075859.9SFTPA1, SFTPA2, SFTPD, CFTR
9positive regulation of phagocytosisGO:0507669.9MBL2, SFTPD
10negative regulation of T cell proliferationGO:0421309.8IL10, HLA-DRB1, SFTPD
11defense response to protozoanGO:0428329.8IL4, IFNG
12negative regulation of growth of symbiont in hostGO:0441309.8IL10, MBL2, IFNG
13positive regulation of MHC class II biosynthetic processGO:0453489.8IFNG, IL4, IL10
14negative regulation of interferon-gamma productionGO:0326899.8HLA-DRB1, IL10
15positive regulation of sequence-specific DNA binding transcription factor activityGO:0510919.7IL4, IL5, IL10
16interferon-gamma-mediated signaling pathwayGO:0603339.7HLA-DQB1, IFNG, HLA-DRB1
17defense response to bacteriumGO:0427429.5IL10, SFTPD, IFNG, MBL2
18chemotaxisGO:0069359.5CCL17, IL4, CCR4, CCL22
19cell-cell signalingGO:0072679.4CCL17, TXN, IL10, CCL22
20cytokine-mediated signaling pathwayGO:0192219.4IL5, HLA-DRB1, IFNG, HLA-DQB1
21response to drugGO:0424939.3IFNG, IL4, IL10, CFTR
22inflammatory responseGO:0069549.1IL5, CCL17, CCL22, IL10, CCR4
23response to radiationGO:0093149.0CCR4, TXN
24immune responseGO:0069558.1HLA-DRB1, IL5, IL4, CCL22, CCR4, CCL17

Molecular functions related to Allergic Bronchopulmonary Aspergillosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1MHC class II receptor activityGO:0323959.7HLA-DRB1, HLA-DQB1
2growth factor activityGO:0080839.6IL10, IL5, IL4
3carbohydrate bindingGO:0302469.5SFTPD, SFTPA1, SFTPA2
4cytokine activityGO:0051259.1IL10, IL5, IL4, IFNG

Products for genes affiliated with Allergic Bronchopulmonary Aspergillosis

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Sources for Allergic Bronchopulmonary Aspergillosis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet