ABPA
MCID: ALL008
MIFTS: 67

Allergic Bronchopulmonary Aspergillosis (ABPA) malady

Rare diseases, Respiratory diseases, Immune diseases, Infectious diseases categories
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Summaries for Allergic Bronchopulmonary Aspergillosis

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Disease Ontology:8 An aspergillosis that involves an allergic reaction due to the spores of aspergillus moulds (a. fumigatus), which colonizes the mucus in the airways causing inflammation. the disease has symptom cough, has symptom wheezing and has symptom fever.

MalaCards based summary: Allergic Bronchopulmonary Aspergillosis, also known as aspergillosis, allergic bronchopulmonary, is related to aspergillosis and asthma, and has symptoms including asthma/bronchospasm, cough and anomalies of the immunitary system. An important gene associated with Allergic Bronchopulmonary Aspergillosis is SFTPA2 (surfactant protein A2), and among its related pathways are IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types and FOXA1 transcription factor network. The compounds betaseron and omalizumab have been mentioned in the context of this disorder. Affiliated tissues include lung, colon and testes, and related mouse phenotypes are digestive/alimentary and liver/biliary system.

Wikipedia:65 Allergic bronchopulmonary aspergillosis (ABPA) is a condition characterised by an exaggerated response... more...

Description from OMIM:46 103920

Aliases & Classifications for Allergic Bronchopulmonary Aspergillosis

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 44Novoseek, 48Orphanet, 46OMIM, 62UMLS, 34MeSH, 39NCIt, 57SNOMED-CT, 27ICD9CM, 35MESH via Orphanet, 26ICD10 via Orphanet, 63UMLS via Orphanet
See all sources

Allergic Bronchopulmonary Aspergillosis, Aliases & Descriptions:

Name: Allergic Bronchopulmonary Aspergillosis 8 42 48 46
Aspergillosis, Allergic Bronchopulmonary 42 62
Allergic Bronchopulmonary Mycosis 42 62
Hinson-Pepys Disease 42 48
 
Abpa 42 48
Aspergillosis Allergic Bronchopulmonary 44
Pulmonary Aspergillus Disease 8
Allergic Aspergillosis 48


Classifications:



Characteristics (Orphanet epidemiological data):

48
allergic bronchopulmonary aspergillosis:
Inheritance: Sporadic; Age of onset: Childhood


External Ids:

Disease Ontology8 DOID:13166
OMIM46 103920
MeSH34 D001229
NCIt39 C84547
SNOMED-CT57 37981002
ICD9CM27 518.6
MESH via Orphanet35 D001229
ICD10 via Orphanet26 B44.1
UMLS via Orphanet63 C0004031

Related Diseases for Allergic Bronchopulmonary Aspergillosis

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Diseases related to Allergic Bronchopulmonary Aspergillosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 135)
idRelated DiseaseScoreTop Affiliating Genes
1aspergillosis32.7MBL2, IFNG, SFTPA2, SFTPD
2asthma31.9IL5, IL4, IGHE, IGES
3cystic fibrosis31.9IGES, SFTPD, CFTR, CCL17, CCL22, MBL2
4sinusitis31.6IGES, IGHE, CFTR, IL5
5bronchiectasis31.4IGES, IGHE, CFTR, MBL2
6atopic dermatitis31.2CCL17, CCL22, IL4
7rhinitis31.1IGES, IGHE, IL4, IL5
8allergic rhinitis31.0IL5, IL4, IGHE
9extrinsic allergic alveolitis31.0IGHE, SFTPD
10chronic obstructive pulmonary disease30.8SFTPD, CFTR, TXN, CCR4
11eosinophilic pneumonia30.8IGHE, CCL17, CCL22, IL5
12bronchitis30.7IGHE, CFTR, IL5
13pulmonary eosinophilia30.7IL5, IL4, SFTPD, IGHE
14respiratory failure30.6IGES, IGHE, SFTPD, CFTR, CCL17
15dermatitis30.2IL5, IL4, IFNG, CCL22, CCR4, CCL17
16atopy30.0IL10, IL5, IL4, IFNG, CCL22, CCL17
17pulmonary tuberculosis30.0HLA-DRB1, HLA-DQB1, IGES, IFNG, IL4, MBL2
18pneumonia29.9MBL2, IL10, IL5, CCL22, CCL17, TXN
19sarcoidosis29.8HLA-DQB1, HLA-DRB1, SFTPD, TXN, CCR4, IFNG
20eosinophilia29.8IFNG, CCR4, CCL17, IGHE, IGES, IL4
21arthritis29.7HLA-DRB1, TXN, IFNG, IL4, IL10
22tuberculosis29.6IGES, HLA-DQB1, HLA-DRB1, SFTPD, CCR4, IFNG
23rheumatoid arthritis28.6HLA-DQB1, HLA-DRB1, SFTPD, CFTR, TXN, CCR4
24middle lobe syndrome10.5
25pneumothorax10.5
26interstitial lung disease10.5SFTPD
27conjunctivitis10.5IGES, IGHE
28eczema herpeticum10.5IGHE
29eosinophilic fasciitis10.5IL5
30eosinophilia-myalgia syndrome10.5IL5
31keratoconjunctivitis10.5IL5
32rheumatic congestive heart failure10.5MBL2
33churg-strauss syndrome10.5
34endocarditis10.5
35cryptosporidiosis10.4MBL2
36keratoconjunctivitis sicca10.4CFTR
37immunoglobulin g deficiency10.4IGHE, MBL2
38leprosy10.4HLA-DRB1
39eosinophilic gastroenteritis10.4IGHE, IL5
40filariasis10.4IL5, IGHE
41strongyloidiasis10.4IL5, IGHE
42adult t-cell leukemia10.4TXN
43lymphomatoid papulosis10.4CCL17, CCR4
44periapical granuloma10.4IL4
45immunodeficiency with hyper igm type 110.4IGHE, IL4
46helminthiasis10.4IGHE, IL5
47otitis media10.3MBL2, IGHE, IGES
48collagen disease10.3MBL2, SFTPD
49kimura disease10.3IGES, IGHE, IL5
50paragonimiasis10.3IL5, CCL17, IGHE

Graphical network of the top 20 diseases related to Allergic Bronchopulmonary Aspergillosis:



Diseases related to allergic bronchopulmonary aspergillosis

Symptoms for Allergic Bronchopulmonary Aspergillosis

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Symptoms by clinical synopsis from OMIM:

103920

Clinical features from OMIM:

103920

Symptoms:

48 (show all 13)
  • asthma/bronchospasm
  • cough
  • anomalies of the immunitary system
  • eosinophils anomalies/hypereosinophilia
  • ground-glass/reticular/alveolar/interstitial lung/pulmonary opacity
  • bronchial dilation/dilatation/bronchiectasia
  • weight loss/loss of appetite/break in weight curve/general health alteration
  • fever/chilling
  • abnormal fingernails
  • respiratory distress/dyspnea/respiratory failure/lung volume reduction
  • emphysema
  • hemoptysis
  • pulmonary hypertension

HPO human phenotypes related to Allergic Bronchopulmonary Aspergillosis:

(show all 12)
id Description Frequency HPO Source Accession
1 abnormality of eosinophils hallmark (90%) HP:0001879
2 asthma hallmark (90%) HP:0002099
3 weight loss typical (50%) HP:0001824
4 abnormality of the bronchi typical (50%) HP:0002109
5 abnormality of temperature regulation typical (50%) HP:0004370
6 abnormality of the fingernails occasional (7.5%) HP:0001231
7 pulmonary hypertension occasional (7.5%) HP:0002092
8 respiratory insufficiency occasional (7.5%) HP:0002093
9 emphysema occasional (7.5%) HP:0002097
10 hemoptysis occasional (7.5%) HP:0002105
11 autosomal dominant inheritance HP:0000006
12 abnormality of the immune system HP:0002715

Drugs & Therapeutics for Allergic Bronchopulmonary Aspergillosis

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Drug clinical trials:

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Search NIH Clinical Center for Allergic Bronchopulmonary Aspergillosis

Genetic Tests for Allergic Bronchopulmonary Aspergillosis

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Anatomical Context for Allergic Bronchopulmonary Aspergillosis

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MalaCards organs/tissues related to Allergic Bronchopulmonary Aspergillosis:

32
Lung, Colon, Testes, T cells, Skin, B cells, Neutrophil

Animal Models for Allergic Bronchopulmonary Aspergillosis or affiliated genes

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MGI Mouse Phenotypes related to Allergic Bronchopulmonary Aspergillosis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.5CFTR, IFNG, IL4, IL5, IL10, HLA-DQB1
2MP:00053708.4HLA-DQB1, CFTR, IFNG, IL4, IL5, IL10
3MP:00053887.7HLA-DQB1, SFTPD, CFTR, CCR4, IFNG, IL4
4MP:00053767.2IGHE, HLA-DQB1, SFTPD, CFTR, IFNG, IL4
5MP:00053976.8MBL2, IGHE, HLA-DQB1, SFTPD, CFTR, CCL17
6MP:00053876.7CFTR, SFTPD, HLA-DQB1, IGHE, CCL17, CCR4

Publications for Allergic Bronchopulmonary Aspergillosis

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Articles related to Allergic Bronchopulmonary Aspergillosis:

(show top 50)    (show all 515)
idTitleAuthorsYear
1
Sinobronchial allergic aspergillosis with allergic bronchopulmonary aspergillosis: a less common co-existence. (25371437)
2014
2
Anti-IgE therapy for allergic bronchopulmonary aspergillosis. (24291616)
2013
3
Allergic bronchopulmonary aspergillosis. (22640845)
2012
4
Clinical features of allergic bronchopulmonary aspergillosis in Korea. (22950037)
2012
5
Serologic allergic bronchopulmonary aspergillosis (ABPA-S): long-term outcomes. (22445696)
2012
6
Blood basophils from cystic fibrosis patients with allergic bronchopulmonary aspergillosis are primed and hyper-responsive to stimulation by aspergillus allergens. (22608296)
2012
7
A rare cause of acute respiratory failure--allergic bronchopulmonary aspergillosis. (20028466)
2011
8
Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis among asthma patients in eastern India. (21661466)
2010
9
Aerosolized amphotericin for the treatment of allergic bronchopulmonary aspergillosis. (20658484)
2010
10
An alternate method of classifying allergic bronchopulmonary aspergillosis based on high-attenuation mucus. (21179536)
2010
11
Codiagnosis of allergic bronchopulmonary aspergillosis and sarcoid in a severe asthmatic patient. (21130394)
2010
12
Voriconazole in the treatment of allergic bronchopulmonary aspergillosis in cystic fibrosis. (19284017)
2009
13
Chronic necrotizing and allergic bronchopulmonary aspergillosis in an asthmatic patient--a therapeutic challenge. (20298342)
2008
14
Multiple bronchoceles in a non-asthmatic patient with allergic bronchopulmonary aspergillosis. (18846804)
2008
15
Frequency of familial occurrence in 164 patients with allergic bronchopulmonary aspergillosis. (18939723)
2008
16
Successful treatment of allergic bronchopulmonary aspergillosis with recombinant anti-IgE antibody. (17329558)
2007
17
Using rare diseases as models for biobehavioral research: allergic bronchopulmonary aspergillosis. (17883921)
2007
18
Case quiz. Thoracic CT illustrating hyperdense bronchial mucous plugging: allergic bronchopulmonary aspergillosis. (12890264)
2003
19
Antifungal therapy for allergic bronchopulmonary aspergillosis. (12743553)
2003
20
Aspergillus antigens associated with allergic bronchopulmonary aspergillosis. (12456371)
2003
21
Azoles for allergic bronchopulmonary aspergillosis associated with asthma. (12917898)
2003
22
Allergic bronchopulmonary aspergillosis, allergic fungal sinusitis, and hypersensitivity pneumonitis. (11577554)
2002
23
Allergic bronchopulmonary aspergillosis. (10893349)
2000
24
Therapy of allergic bronchopulmonary aspergillosis. (15597668)
2000
25
Increased sensitivity to IL-4 in patients with allergic bronchopulmonary aspergillosis. (11146389)
2000
26
Accuracy of CT in the diagnosis of allergic bronchopulmonary aspergillosis in asthmatic patients. (10511153)
1999
27
Specific IgG subclass antibody pattern to Aspergillus fumigatus in patients with cystic fibrosis with allergic bronchopulmonary aspergillosis (ABPA). (10343631)
1999
28
The role of bronchial biopsy and washing in the diagnosis of allergic bronchopulmonary aspergillosis. (9688180)
1998
29
Recurrence of allergic bronchopulmonary aspergillosis in the posttransplant lungs of a cystic fibrosis patient. (9228393)
1997
30
The use of bronchofiberscopy for diagnosis of allergic bronchopulmonary aspergillosis. (9475240)
1997
31
Prevalence of allergic bronchopulmonary aspergillosis and atopy in adult patients with cystic fibrosis. (8769507)
1996
32
Immunohistochemical detection of GM-CSF, IL-4 and IL-5 in a murine model of allergic bronchopulmonary aspergillosis. (8732244)
1996
33
Successful treatment of fungus ball in a patient with allergic bronchopulmonary aspergillosis: continuous percutaneous instillation of antifungal agents into the cavity. (8915703)
1996
34
T cell subsets, epitope mapping, and HLA-restriction in patients with allergic bronchopulmonary aspergillosis. (8636413)
1996
35
Allergic bronchopulmonary aspergillosis: an unusual complication of bronchial asthma. (8920604)
1995
36
Problems with skin testing in patients with allergic bronchopulmonary aspergillosis. (8603286)
1995
37
Management of allergic bronchopulmonary aspergillosis. (8029520)
1994
38
Diagnosis and management of allergic bronchopulmonary aspergillosis. (7721084)
1994
39
Serum anti-Aspergillus fumigatus antibodies by immunoblot and ELISA in cystic fibrosis with allergic bronchopulmonary aspergillosis. (8182235)
1994
40
Pneumothorax and bronchopleural fistula during treatment of allergic bronchopulmonary aspergillosis. (8367756)
1993
41
Concanavalin A-nonbinding Aspergillus fumigatus antigen: a major immunogen in allergic bronchopulmonary aspergillosis. (1583388)
1992
42
A murine model of allergic bronchopulmonary aspergillosis with elevated eosinophils and IgE. (1602128)
1992
43
Adjunctive therapy of allergic bronchopulmonary aspergillosis with itraconazole. (1653680)
1991
44
Pathologic features of allergic bronchopulmonary aspergillosis. (3344888)
1988
45
Allergic bronchopulmonary aspergillosis in a young child: diagnostic confirmation by serum IgE and IgG indices. (3954164)
1986
46
Environmental aerobiological studies in allergic bronchopulmonary aspergillosis. (6711771)
1984
47
Varying presentations of allergic bronchopulmonary aspergillosis. (6365793)
1984
48
Allergic bronchopulmonary aspergillosis: reactivity of IgE and IgG antibodies with antigenic components of Aspergillus fumigatus (IgE/IgG antigen complexes). (6605984)
1983
49
Mould counts and exacerbations of allergic bronchopulmonary aspergillosis. (6342846)
1983
50
Allergic bronchopulmonary aspergillosis in cystic fibrosis. (7138421)
1982

Variations for Allergic Bronchopulmonary Aspergillosis

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Expression for genes affiliated with Allergic Bronchopulmonary Aspergillosis

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Expression patterns in normal tissues for genes affiliated with Allergic Bronchopulmonary Aspergillosis

Search GEO for disease gene expression data for Allergic Bronchopulmonary Aspergillosis.

Pathways for genes affiliated with Allergic Bronchopulmonary Aspergillosis

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Pathways related to Allergic Bronchopulmonary Aspergillosis according to GeneCards/GeneDecks:

(show all 34)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.9IL5, IL4
2
Show member pathways
FOXA transcription factor networks37
9.8SFTPD, SFTPA1, SFTPA2
39.7SFTPA1, SFTPA2, IL10
49.6IL5, IL4, HLA-DRB1
5
Show member pathways
Calcium signaling in the CD4+ TCR pathway37
9.5IFNG, IL4, IL5
69.5IFNG, IL4, IL5
79.5IL5, IL4, IFNG
8
Show member pathways
Immune response IL 12 induced IFN gamma production60
9.5IL4, IFNG, HLA-DRB1
9
Show member pathways
9.4CCL22, CCR4, CCL17
109.4HLA-DQB1, HLA-DRB1, IFNG
119.3IL10, IL4, TXN
12
Show member pathways
Immune response T cell receptor signaling pathway60
Immune response CD28 signaling60
Immune response ICOS pathway in T helper cell60
9.3IGHE, HLA-DQB1, HLA-DRB1
139.2HLA-DQB1, HLA-DRB1, IL10, MBL2
14
Show member pathways
BCR signaling pathway37
TCR Signaling Pathway37
9.1IFNG, IL4, IL5, IL10
15
Show member pathways
Type III interferon signaling37
9.1IFNG, IL4, IL5, IL10
169.1IL10, IL5, IL4, IFNG
179.1IL10, IL5, IL4, IFNG
18
Show member pathways
9.1IL4, IFNG, HLA-DRB1, HLA-DQB1
19
Show member pathways
9.1IL5, IFNG, HLA-DRB1, HLA-DQB1
20
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
9.0SFTPD, SFTPA1, CFTR, IFNG, IL4
21
Show member pathways
9.0IL10, IFNG, HLA-DRB1, HLA-DQB1
229.0IL10, IFNG, HLA-DRB1, HLA-DQB1
239.0IL10, IFNG, HLA-DRB1, HLA-DQB1
248.9HLA-DQB1, HLA-DRB1, SFTPD, SFTPA1, SFTPA2, MBL2
258.8IGHE, CCL17, IL4, IL5, IL10
268.8IL10, IL5, IL4, IFNG, HLA-DRB1
27
Show member pathways
8.7CCL17, CCL22, IFNG, IL4, IL5, IL10
28
Show member pathways
8.5CCL17, CCR4, CCL22, IL4, IL5, IL10
29
Show member pathways
8.5CCL17, CCR4, CCL22, IL4, IL5, IL10
30
Show member pathways
8.5CCL17, CCR4, CCL22, IL4, IL5, IL10
31
Show member pathways
8.5HLA-DQB1, HLA-DRB1, IFNG, IL4, IL5, IL10
32
Show member pathways
8.5HLA-DQB1, HLA-DRB1, IFNG, IL4, IL5, IL10
33
Show member pathways
8.3HLA-DQB1, HLA-DRB1, SRSF7, IFNG, IL4
34
Show member pathways
8.1CCL17, CCR4, CCL22, IFNG, IL4, IL5

Compounds for genes affiliated with Allergic Bronchopulmonary Aspergillosis

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Compounds related to Allergic Bronchopulmonary Aspergillosis according to GeneCards/GeneDecks:

(show top 50)    (show all 132)
idCompoundScoreTop Affiliating Genes
1betaseron449.8IL10, IFNG, IL4
2omalizumab44 1110.8IL4, IL5, IGHE
3interferon gamma449.8IFNG, IL4, IL10
4alpha-galactosylceramide449.7IL4, IL10, IFNG
5ovomucoid449.7IL5, IL4, IGHE
6nedocromil sodium449.6IGHE, IL4, IL5
7anti-fungal449.6MBL2, IL5, IFNG, SFTPD
8polymyxin b449.6IL4, IL10, MBL2, IFNG
9il-12449.5IL10, IFNG, IL4, IL5
10gm-csf44 2810.5IL4, IFNG, IL10, IL5
11tuberculin449.5MBL2, IL10, IFNG
12polyinosinic-polycytidylic acid449.5IL5, IFNG, IL4, IL10
13rolipram44 61 2811.5IFNG, IL4, IL5, IL10
14ribavirin44 50 1111.5MBL2, IL10, IL4, IFNG
15praziquantel44 1110.4IL10, IL5, IL4, IGHE
16montelukast44 50 28 1112.4IGHE, IL10, IL5, IL4
17neopterin449.4MBL2, IL4, IFNG, IL10
18il 10449.4IL10, IL5, IL4, CCL17, IFNG
19fluticasone propionate44 50 61 1112.4IGHE, IFNG, IL5, IL4
20con a449.3IFNG, IL4, IL5, IL10, MBL2
21gold sodium thiomalate449.3IFNG, TXN, HLA-DRB1
22glatiramer acetate44 1110.2HLA-DRB1, IL4, IL5, IFNG, IL10
23infliximab44 50 1111.2IFNG, IL4, IL10, IGHE
24budesonide44 50 1111.2SFTPD, IL4, IGHE, IL5, IFNG
25methacholine44 50 1111.2IL5, CCL22, IGES, IL4, IGHE
26tacrolimus44 50 1111.1CCL22, IL10, IL4, IL5, CCL17, IFNG
2715-deoxy-delta-12,14-prostaglandin j2449.1IL4, IL10, IFNG, TXN
28ccl344 2810.1IL10, CCL22, IFNG, CCL17, CCR4
29ivig449.0IGHE, IFNG, IL4, IL10, IL5
30hydrocortisone44 2 61 1112.0IFNG, IL4, IL10, IL5, IGHE
31carbohydrates449.0MBL2, IGHE, TXN, CFTR, SFTPD
32sb 20358044 619.9IL10, IL4, IFNG, CCL22, IL5
33pge2448.9CFTR, IL10, CCL22, IL5, IL4, IFNG
34paraffin448.7IL4, IL5, IL10, MBL2, CFTR, CCR4
35thyroxine44 249.7IL4, TXN, IL5, IL10, MBL2, IGHE
36vitamin d448.6IGHE, TXN, MBL2, IL10, IL5, CFTR
37glutamine448.6SFTPD, IGHE, CFTR, TXN, IL5, HLA-DQB1
38indomethacin44 28 61 1111.4IGHE, CFTR, IFNG, IL5, IL4
39adenylate448.4TXN, CCL22, IL5, IL4, CFTR, IGHE
40aspartate448.3IGHE, HLA-DQB1, TXN, IL10, CFTR, MBL2
41rantes448.3IL10, MBL2, IFNG, CCL22, CCR4, IL5
42prednisolone44 28 1110.2IGHE, SFTPD, IL5, IL10, MBL2, IFNG
43histamine44 28 2410.1IL4, IL10, IFNG, CCL22, IL5, SFTPD
44vegf448.1MBL2, IFNG, TXN, IGHE, IL4, IL10
45tarc448.0IL5, CCL17, IGHE, CCR4, CCL22, IFNG
46cycloheximide448.0IFNG, IL5, IGHE, TXN, IL4, IL10
47allergens447.8IFNG, CCL17, IL10, IL5, IGES, IGHE
48arginine447.5IL4, IL5, IGHE, HLA-DRB1, TXN, SRSF7
49cyclosporin a44 28 619.4IFNG, CCL22, IL10, CCL17, TXN, CFTR
50dexamethasone44 50 28 1110.3MBL2, IFNG, IGHE, SFTPD, IL10, IL5

GO Terms for genes affiliated with Allergic Bronchopulmonary Aspergillosis

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Cellular components related to Allergic Bronchopulmonary Aspergillosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1MHC class II protein complexGO:0426139.8HLA-DRB1, HLA-DQB1
2collagenGO:0055819.5SFTPD, SFTPA1, SFTPA2, MBL2
3external side of plasma membraneGO:0098978.5IL4, IFNG, CCR4, HLA-DRB1
4extracellular regionGO:0055767.9IGHE, SFTPD, SFTPA1, SFTPA2, CCL17, CCL22
5extracellular spaceGO:0056157.9MBL2, SFTPD, SFTPA1, SFTPA2, CCL17, CCL22

Biological processes related to Allergic Bronchopulmonary Aspergillosis according to GeneCards/GeneDecks:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1regulation of isotype switchingGO:04519110.1IL10, IL4
2type 2 immune responseGO:04209210.1IL4, IL10
3immunoglobulin production involved in immunoglobulin mediated immune responseGO:00238110.0HLA-DRB1, HLA-DQB1
4positive regulation of isotype switching to IgG isotypesGO:04830410.0IL4, IFNG
5positive regulation of chemokine biosynthetic processGO:04508010.0IFNG, IL4
6humoral immune response mediated by circulating immunoglobulinGO:00245510.0HLA-DQB1, HLA-DRB1
7negative regulation of nitric oxide biosynthetic processGO:0450199.9IL4, IL10
8respiratory gaseous exchangeGO:0075859.9SFTPD, SFTPA1, SFTPA2, CFTR
9positive regulation of phagocytosisGO:0507669.9MBL2, SFTPD
10negative regulation of T cell proliferationGO:0421309.8IL10, SFTPD, HLA-DRB1
11defense response to protozoanGO:0428329.8IL4, IFNG
12negative regulation of growth of symbiont in hostGO:0441309.8IFNG, IL10, MBL2
13positive regulation of MHC class II biosynthetic processGO:0453489.8IL10, IL4, IFNG
14negative regulation of interferon-gamma productionGO:0326899.8IL10, HLA-DRB1
15positive regulation of sequence-specific DNA binding transcription factor activityGO:0510919.7IL10, IL5, IL4
16interferon-gamma-mediated signaling pathwayGO:0603339.7HLA-DQB1, HLA-DRB1, IFNG
17defense response to bacteriumGO:0427429.5SFTPD, IFNG, IL10, MBL2
18chemotaxisGO:0069359.5CCL17, CCR4, CCL22, IL4
19cell-cell signalingGO:0072679.4TXN, CCL17, CCL22, IL10
20cytokine-mediated signaling pathwayGO:0192219.4IL5, IFNG, HLA-DRB1, HLA-DQB1
21response to drugGO:0424939.3CFTR, IFNG, IL4, IL10
22inflammatory responseGO:0069549.1IL10, IL5, CCL22, CCR4, CCL17
23response to radiationGO:0093149.0CCR4, TXN
24immune responseGO:0069558.1IL5, IGHE, HLA-DQB1, HLA-DRB1, CCL17, CCR4

Molecular functions related to Allergic Bronchopulmonary Aspergillosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1MHC class II receptor activityGO:0323959.7HLA-DRB1, HLA-DQB1
2growth factor activityGO:0080839.6IL10, IL5, IL4
3carbohydrate bindingGO:0302469.5SFTPD, SFTPA1, SFTPA2
4cytokine activityGO:0051259.1IL10, IL5, IL4, IFNG

Products for genes affiliated with Allergic Bronchopulmonary Aspergillosis

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Sources for Allergic Bronchopulmonary Aspergillosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet