MCID: ALL008
MIFTS: 56

Allergic Bronchopulmonary Aspergillosis

Categories: Rare diseases, Immune diseases, Respiratory diseases, Genetic diseases, Infectious diseases

Aliases & Classifications for Allergic Bronchopulmonary Aspergillosis

MalaCards integrated aliases for Allergic Bronchopulmonary Aspergillosis:

Name: Allergic Bronchopulmonary Aspergillosis 12 72 49 14
Aspergillosis, Allergic Bronchopulmonary 49 41 69
Allergic Bronchopulmonary Mycosis 49 69
Aspergillosis Allergic Bronchopulmonary 51
Pulmonary Aspergillus Disease 12
Hinson-Pepys Disease 49
Abpa 49

Classifications:



Summaries for Allergic Bronchopulmonary Aspergillosis

NIH Rare Diseases : 49 Allergic bronchopulmonary aspergillosis is an allergic lung reaction to a type of fungus (Aspergillus fumigatus). Symptoms vary, but may include wheezing, bronchial hyperreactivity, hemoptysis, productive cough, low-grade fever, malaise, and weight loss. It is more common in people who have asthma or cystic fibrosis. The recommended treatment for allergic bronchopulmonary aspergillosis is itraconazole, a prescription antifungal medication. Oral corticosteroids, like prednisone, may also be helpful. The clinical course of allergic bronchopulmonary aspergillosis is variable. Many people with this condition can be stabilized for long periods when treated. However, only about 50% of patients achieve long-lasting remission and many require recurrent courses of treatment. Last updated: 5/21/2015

MalaCards based summary : Allergic Bronchopulmonary Aspergillosis, also known as aspergillosis, allergic bronchopulmonary, is related to aspergillosis and sinusitis, and has symptoms including cough, wheezing and fever. An important gene associated with Allergic Bronchopulmonary Aspergillosis is IL4 (Interleukin 4), and among its related pathways/superpathways are Bacterial infections in CF airways and Phagosome. The drugs Itraconazole and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include lung, colon and testes, and related phenotypes are hematopoietic system and immune system

Disease Ontology : 12 An aspergillosis that involves an allergic reaction due to the spores of Aspergillus moulds (A. fumigatus), which colonizes the mucus in the airways causing inflammation. The disease has symptom cough, has symptom wheezing and has symptom fever.

Wikipedia : 72 Allergic bronchopulmonary aspergillosis (ABPA) is a condition characterised by an exaggerated response... more...

Related Diseases for Allergic Bronchopulmonary Aspergillosis

Diseases in the Allergic Bronchopulmonary Aspergillosis family:

Allergic Bronchopulmonary Aspergillosis, Familial

Diseases related to Allergic Bronchopulmonary Aspergillosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 111)
# Related Disease Score Top Affiliating Genes
1 aspergillosis 31.2 CCL17 CFTR IL4 IL5 MBL2 SFTPA2
2 sinusitis 31.1 CFTR IL5
3 cystic fibrosis 30.8 CFTR MBL2 SFTPD
4 cough variant asthma 30.5 IL4 IL5
5 churg-strauss syndrome 30.5 CCL17 IL5
6 pneumonia 30.4 IL5 MBL2 SFTPD
7 rhinitis 30.3 EPX IL4 IL5
8 eosinophilic gastroenteritis 30.3 EPX IL5
9 dermatitis 30.2 CCL17 IL4 IL5
10 allergic rhinitis 30.2 EPX IL4 IL5
11 asthma 30.1 CCL17 CFTR EPX IL4 IL5
12 allergic hypersensitivity disease 30.0 CCL17 EPX IL4 IL5
13 gastroenteritis 29.9 IL4 IL5
14 eosinophilic pneumonia 29.7 CCL17 IL5 SFTPD
15 dermatitis, atopic 29.7 CCL17 EPX IL4 IL5
16 lung disease 29.5 CFTR IL5 SFTPA2 SFTPD
17 pulmonary eosinophilia 29.5 CCL17 EPX IL4 IL5
18 allergic bronchopulmonary aspergillosis, familial 12.5
19 plastic bronchitis 11.3
20 fibrosis of extraocular muscles, congenital, 1 11.0
21 egg allergy 10.4 IL4 IL5
22 trichinosis 10.4 IL4 IL5
23 atopic keratoconjunctivitis 10.4 IL4 IL5
24 non-suppurative otitis media 10.4 IL4 IL5
25 scleritis 10.4 IL4 IL5
26 intrinsic asthma 10.4 IL4 IL5
27 angiostrongyliasis 10.4 IL4 IL5
28 angel-shaped phalangoepiphyseal dysplasia 10.4
29 mycobacterium tuberculosis 1 10.4
30 pulmonary tuberculosis 10.4
31 bronchiectasis 10.4
32 gastrointestinal allergy 10.4 IL4 IL5
33 latex allergy 10.4 IL4 IL5
34 eosinophilic meningitis 10.4 IL4 IL5
35 cercarial dermatitis 10.4 IL4 IL5
36 intestinal schistosomiasis 10.4 IL4 IL5
37 chronic conjunctivitis 10.4 IL4 IL5
38 eosinophilic gastritis 10.4 IL4 IL5
39 kimura disease 10.4 IL4 IL5
40 vulvovaginal candidiasis 10.4 IL4 MBL2
41 chronic tic disorder 10.4 IL4 IL5
42 folliculitis 10.4 IL4 IL5
43 vernal keratoconjunctivitis 10.4 IL4 IL5
44 toxic oil syndrome 10.4 IL4 IL5
45 primary amebic meningoencephalitis 10.3 IL4 IL5
46 cryptococcosis 10.3 IL4 MBL2
47 conjunctival disease 10.3 IL4 IL5
48 enterobiasis 10.3 IL4 IL5
49 milk allergy 10.3 IL4 IL5
50 paranasal sinus disease 10.3 IL4 IL5

Graphical network of the top 20 diseases related to Allergic Bronchopulmonary Aspergillosis:



Diseases related to Allergic Bronchopulmonary Aspergillosis

Symptoms & Phenotypes for Allergic Bronchopulmonary Aspergillosis

Symptoms:

12
  • cough
  • wheezing
  • fever

Human phenotypes related to Allergic Bronchopulmonary Aspergillosis:

31 (show all 12)
# Description HPO Frequency HPO Source Accession
1 abnormality of the fingernails 31 occasional (7.5%) HP:0001231
2 weight loss 31 frequent (33%) HP:0001824
3 abnormality of eosinophils 31 hallmark (90%) HP:0001879
4 pulmonary arterial hypertension 31 occasional (7.5%) HP:0002092
5 respiratory insufficiency 31 occasional (7.5%) HP:0002093
6 emphysema 31 occasional (7.5%) HP:0002097
7 asthma 31 hallmark (90%) HP:0002099
8 hemoptysis 31 occasional (7.5%) HP:0002105
9 bronchiectasis 31 frequent (33%) HP:0002110
10 cerebral cortical atrophy 31 frequent (33%) HP:0002120
11 low-grade fever 31 frequent (33%) HP:0011134
12 cough 31 hallmark (90%) HP:0012735

MGI Mouse Phenotypes related to Allergic Bronchopulmonary Aspergillosis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.5 CCL17 CFTR EPX IL4 IL5 MBL2
2 immune system MP:0005387 9.17 CCL17 CFTR EPX IL4 IL5 MBL2

Drugs & Therapeutics for Allergic Bronchopulmonary Aspergillosis

Drugs for Allergic Bronchopulmonary Aspergillosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 63)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Itraconazole Approved, Investigational Phase 4,Phase 2,Phase 3 84625-61-6 55283
2
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 22916-47-8 4189
3
Omalizumab Approved, Investigational Phase 4 242138-07-4
4 Anti-Allergic Agents Phase 4,Phase 2,Phase 3
5 Anti-Asthmatic Agents Phase 4,Phase 2,Phase 3
6 Antibodies Phase 4
7 Antifungal Agents Phase 4,Phase 2,Phase 3
8 Anti-Infective Agents Phase 4,Phase 2,Phase 3
9 Cytochrome P-450 CYP3A Inhibitors Phase 4,Phase 2,Phase 3
10 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 2,Phase 3
11 Hormone Antagonists Phase 4,Phase 2,Phase 3
12 Hormones Phase 4,Phase 2,Phase 3
13 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3
14 Hydroxyitraconazole Phase 4,Phase 2,Phase 3
15 Immunoglobulin E Phase 4
16 Immunoglobulins Phase 4
17 Respiratory System Agents Phase 4,Phase 2,Phase 3
18 Steroid Synthesis Inhibitors Phase 4,Phase 2,Phase 3
19
Methylprednisolone Approved, Vet_approved Phase 2, Phase 3 83-43-2 6741
20
Prednisolone Approved, Vet_approved Phase 2, Phase 3 50-24-8 5755
21
Voriconazole Approved, Investigational Phase 2, Phase 3 137234-62-9 71616
22
Amphotericin B Approved, Investigational Phase 2, Phase 3 1397-89-3 5280965 14956
23
Budesonide Approved Phase 2, Phase 3 51333-22-3 5281004 63006
24
deoxycholic acid Approved Phase 2, Phase 3 83-44-3 222528
25
Cholecalciferol Approved, Nutraceutical Phase 2, Phase 3, Phase 1 67-97-0 10883523 5280795 6221
26
Ergocalciferol Approved, Nutraceutical Phase 2, Phase 3,Phase 1 50-14-6 5280793
27
Vitamin D Approved, Nutraceutical, Vet_approved Phase 2, Phase 3,Phase 1 1406-16-2
28 glucocorticoids Phase 2, Phase 3
29 Methylprednisolone acetate Phase 2, Phase 3
30 Methylprednisolone Hemisuccinate Phase 2, Phase 3
31 Prednisolone acetate Phase 2, Phase 3
32 Prednisolone hemisuccinate Phase 2, Phase 3
33 Prednisolone phosphate Phase 2, Phase 3
34 Antiemetics Phase 2, Phase 3
35 Anti-Inflammatory Agents Phase 2, Phase 3
36 Antineoplastic Agents, Hormonal Phase 2, Phase 3
37 Autonomic Agents Phase 2, Phase 3
38
Fluticasone Phase 2, Phase 3 80474-14-2, 90566-53-3 22833648 62924
39 Formoterol Fumarate Phase 2, Phase 3
40 Gastrointestinal Agents Phase 2, Phase 3
41 Neuroprotective Agents Phase 2, Phase 3
42 Peripheral Nervous System Agents Phase 2, Phase 3
43 Protective Agents Phase 2, Phase 3
44 Adrenergic Agents Phase 2, Phase 3
45 Adrenergic Agonists Phase 2, Phase 3
46 Adrenergic beta-2 Receptor Agonists Phase 2, Phase 3
47 Adrenergic beta-Agonists Phase 2, Phase 3
48 Amphotericin B, deoxycholate drug combination Phase 2, Phase 3
49 Anti-Bacterial Agents Phase 2, Phase 3
50 Antiparasitic Agents Phase 2, Phase 3

Interventional clinical trials:

(show all 18)

# Name Status NCT ID Phase Drugs
1 An Exploratory Study to Assess Multiple Doses of Omalizumab in Patients With Cystic Fibrosis Complicated by Acute Bronchopulmonary Aspergillosis (ABPA) Terminated NCT00787917 Phase 4 Omalizumab;Placebo;Itraconazole
2 Trial on the Efficacy and Safety of Two Different Glucocorticoid Dose Regimens in Allergic Bronchopulmonary Aspergillosis Completed NCT00974766 Phase 2, Phase 3 Glucocorticoids;Glucocorticoids
3 Voriconazole Versus Oral Steroids in Allergic Bronchopulmonary Aspergillosis Completed NCT01621321 Phase 2, Phase 3 Prednisolone;Voriconazole
4 A Randomized Controlled Trial of Inhaled Amphotericin B for Maintaining Remission in Allergic Bronchopulmonary Aspergillosis Completed NCT01857479 Phase 2, Phase 3 Inhaled budesonide;Inhaled amphotericin
5 Monotherapy of Itraconazole Versus Prednisolone in Allergic Bronchopulmonary Aspergillosis Completed NCT01321827 Phase 2, Phase 3 Glucocorticoids;Itraconazole
6 A Randomized Trial of Itraconazole in Acute Stages of Allergic Bronchopulmonary Aspergillosis Recruiting NCT02440009 Phase 2, Phase 3 Itraconazole;Glucocorticoids
7 A Study Evaluating Vitamin D in Allergic Bronchopulmonary Aspergillosis Complicating Asthma Not yet recruiting NCT03133299 Phase 2, Phase 3 Glucocorticoids;Vitamin D
8 Open-label Vitamin D Trial for Patients With Cystic Fibrosis and Allergic Bronchopulmonary Aspergillosis Completed NCT01222273 Phase 1, Phase 2
9 Evaluation of a Therapeutic Strategy Including Nebulised Liposomal Amphotericin B (Ambisome®) in Maintenance Treatment of Allergic Bronchopulmonary Aspergillosis (Cystic Fibrosis Excluded). Active, not recruiting NCT02273661 Phase 2 Liposomal amphotericin B (Ambisome®);placebo
10 Safety, Tolerability, Pharmacokinetics, and Preliminary Pharmacodynamics of QBW251 in Healthy Subjects and Cystic Fibrosis Patients Terminated NCT02190604 Phase 1, Phase 2 Placebo;QBW251
11 Lung MRI and Allergic Broncho-pulmonary Aspergillosis in Cystic Fibrosis Completed NCT02853175
12 Mechanisms of Immune Tolerance and Inflammation in Patients With Cystic Fibrosis With ABPA Completed NCT00585364
13 Protocol TARC-ABPA Completed NCT01710930
14 Evaluation of Bronchial Inflammation in Allergic Bronchopulmonary Aspergillosis (ABPA) Completed NCT00906568
15 Duplication in CHIT1 Gene and the Risk for Aspergillus Lung Disease in CF Patients Completed NCT01572870
16 Natural History of Bronchiectasis Recruiting NCT00943514
17 Diagnostic Value of MRI for Allergic Broncho-Pulmonary Aspergilloses Not yet recruiting NCT03265366
18 Role of Thymus-And Activation-Regulated Chemokine (TARC) In Diagnosis Of Allergic Bronchopulmonary Aspergillosis Not yet recruiting NCT03267394

Search NIH Clinical Center for Allergic Bronchopulmonary Aspergillosis

Cochrane evidence based reviews: aspergillosis, allergic bronchopulmonary

Genetic Tests for Allergic Bronchopulmonary Aspergillosis

Anatomical Context for Allergic Bronchopulmonary Aspergillosis

MalaCards organs/tissues related to Allergic Bronchopulmonary Aspergillosis:

38
Lung, Colon, Testes, T Cells, Skin, Bone, Thymus

Publications for Allergic Bronchopulmonary Aspergillosis

Articles related to Allergic Bronchopulmonary Aspergillosis:

(show top 50) (show all 615)
# Title Authors Year
1
A Randomized Trial of Itraconazole vs Prednisolone in Acute-Stage Allergic Bronchopulmonary Aspergillosis Complicating Asthma. ( 29331473 )
2018
2
Vitamin D levels in asthmatic patients with and without allergic bronchopulmonary aspergillosis. ( 29314357 )
2018
3
Multivariate Analysis As a Support for Diagnostic Flowcharts in Allergic Bronchopulmonary Aspergillosis: A Proof-of-Concept Study. ( 28878778 )
2017
4
Identifying rare diseases using electronic medical records: the example of allergic bronchopulmonary aspergillosis. ( 28370596 )
2017
5
F508del CFTR gene mutation in patients with allergic bronchopulmonary aspergillosis. ( 29035608 )
2017
6
Two cases of non-cystic fibrosis (CF) bronchiectasis with allergic bronchopulmonary aspergillosis. ( 28053855 )
2017
7
Allergic bronchopulmonary aspergillosis in Japan: A nationwide survey. ( 28546015 )
2017
8
Inverted Mucoid Impaction Signal in Allergic Bronchopulmonary Aspergillosis: Are We Calling a Spade a Big Spoon? ( 29045221 )
2017
9
Increasing Total Serum IgE, Allergic Bronchopulmonary Aspergillosis, and Lung Function in Cystic Fibrosis. ( 28526275 )
2017
10
Prevalence of Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with bronchial asthma at a tertiary care center in North India. ( 28360463 )
2017
11
Effect of allergic bronchopulmonary aspergillosis on FEV1 in children and adolescents with cystic fibrosis: a European Cystic Fibrosis Society Patient Registry analysis. ( 28325727 )
2017
12
A review of 42 asthmatic children with allergic bronchopulmonary aspergillosis. ( 28765819 )
2017
13
Allergic Bronchopulmonary Aspergillosis. ( 28483324 )
2017
14
Combination omalizumab and mepolizumab therapy for refractory allergic bronchopulmonary aspergillosis. ( 28279664 )
2017
15
Coexistence of Pulmonary Aspergilloma and Allergic Bronchopulmonary Aspergillosis. ( 28768986 )
2017
16
Diagnosis of Allergic Bronchopulmonary Aspergillosis Exacerbations. ( 29122158 )
2017
17
Omalizumab treatment for allergic bronchopulmonary aspergillosis in young patients with cystic fibrosis. ( 29173443 )
2017
18
Mucus plugging in allergic bronchopulmonary aspergillosis: Implication of the eosinophil DNA traps. ( 28886913 )
2017
19
Clinical Analysis of 77 Patients with Allergic Bronchopulmonary Aspergillosis in Peking Union Medical College Hospital. ( 28695805 )
2017
20
Allergic bronchopulmonary aspergillosis causing bendopnea. ( 28474666 )
2017
21
Allergic Bronchopulmonary Aspergillosis in Cystic Fibrosis: MR Imaging of Airway Mucus Contrasts as a Tool for Diagnosis. ( 28530849 )
2017
22
Successful Treatment of Allergic Bronchopulmonary Aspergillosis With Isavuconazole: Case Report and Review of the Literature. ( 28491888 )
2017
23
Modern challenges of allergic bronchopulmonary aspergillosis diagnosis and management: Finding from a case study with a history of rituximab use. ( 28668248 )
2017
24
Case series of omalizumab for allergic bronchopulmonary aspergillosis in cystic fibrosis patients. ( 27717223 )
2017
25
Allergic bronchopulmonary aspergillosis in patients with cystic fibrosis. ( 28469716 )
2017
26
Allergic bronchopulmonary aspergillosis treated successfully with omalizumab. ( 28705584 )
2017
27
Beneficial effects of Omalizumab therapy in allergic bronchopulmonary aspergillosis: A synthesis review of published literature. ( 27993289 )
2017
28
Delayed diagnosis of allergic bronchopulmonary aspergillosis due to absence of asthmatic symptoms. ( 27489792 )
2016
29
A pilot randomized trial of nebulized amphotericin in patients with allergic bronchopulmonary aspergillosis. ( 26666774 )
2016
30
Childhood allergic bronchopulmonary aspergillosis presenting as a middle lobe syndrome. ( 26844222 )
2016
31
Allergic bronchopulmonary aspergillosis presenting as pulmonary hypertension. ( 27728618 )
2016
32
Tombs of Aspergillus: A missed cause of recurrent respiratory infections in allergic bronchopulmonary aspergillosis. ( 27555698 )
2016
33
Coexisting atopic conditions influence the likelihood of allergic bronchopulmonary aspergillosis in asthma. ( 27234940 )
2016
34
Human Immunodeficiency Virus and Allergic Bronchopulmonary Aspergillosis: Case Report and Review of Literature. ( 27419184 )
2016
35
Are allergic fungal rhinosinusitis and allergic bronchopulmonary aspergillosis lifelong conditions? ( 27601608 )
2016
36
Allergic bronchopulmonary aspergillosis in a patient with rheumatoid arthritis under adalimumab therapy: a case report. ( 27181240 )
2016
37
Antifungal therapies for allergic bronchopulmonary aspergillosis in people with cystic fibrosis. ( 27820955 )
2016
38
Developments in the diagnosis and treatment of allergic bronchopulmonary aspergillosis. ( 27744712 )
2016
39
Treating allergic bronchopulmonary aspergillosis: the way forward. ( 26828049 )
2016
40
Allergic Bronchopulmonary Aspergillosis masquerading as recurrent bacterial pneumonia. ( 27453814 )
2016
41
Blood basophil activation is a reliable biomarker of allergic bronchopulmonary aspergillosis in cystic fibrosis. ( 26585435 )
2016
42
Molecular-based allergy diagnosis of allergic bronchopulmonary aspergillosis in Aspergillus fumigatus-sensitized Japanese patients. ( 26817858 )
2016
43
Allergic Bronchopulmonary Aspergillosis: All A Radiologist Needs To Know. ( 27585455 )
2016
44
Allergic Bronchopulmonary Aspergillosis: A Perplexing Clinical Entity. ( 27126721 )
2016
45
"Blood basophil activation is a reliable biomarker of allergic bronchopulmonary aspergillosis in cystic fibrosis." Yael Gernez, Jeffrey Waters, Bojana MirkoviA8, Gillian M. Lavelle, Colleen E. Dunn, Zoe A. Davies, Cassie Everson, Rabindra Tirouvanziam, Elana Silver, Sylvan Wallenstein, Sanjay H. Chotirmall, Noel G. McElvaney, Leonore A. Herzenberg and Richard B. Moss. Eur Respir J 2016; 47: 177-185. ( 27246085 )
2016
46
Fungal Allergens in a Saxophonist Who Had Never Smoked With Allergic Bronchopulmonary Aspergillosis Previously Diagnosed as COPD. ( 27996950 )
2016
47
Omalizumab Treatment for Allergic Bronchopulmonary Aspergillosis in Cystic Fibrosis. ( 26699090 )
2016
48
Basophil activation test determination of CD63 combined with CD203c is not superior to CD203c alone in identifying allergic bronchopulmonary aspergillosis in cystic fibrosis. ( 27215492 )
2016
49
Question 11: How should Allergic Bronchopulmonary Aspergillosis [ABPA] be managed in Cystic Fibrosis? ( 27964950 )
2016
50
Allergic bronchopulmonary aspergillosis complicating Swyer-James-Macleod's syndrome: case report and review of literature. ( 27152607 )
2016

Variations for Allergic Bronchopulmonary Aspergillosis

Expression for Allergic Bronchopulmonary Aspergillosis

Search GEO for disease gene expression data for Allergic Bronchopulmonary Aspergillosis.

Pathways for Allergic Bronchopulmonary Aspergillosis

Pathways related to Allergic Bronchopulmonary Aspergillosis according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.8 CFTR IL4 SFTPD
2 11.73 MBL2 SFTPA2 SFTPD
3
Show member pathways
11.59 CCL17 CFTR IL4 IL5
4 11.23 CCL17 IL4 IL5
5
Show member pathways
11.21 SFTPA2 SFTPD
6
Show member pathways
11.17 SFTPA2 SFTPD
7 11.13 IL4 IL5 SFTPA2
8 11.04 IL4 IL5
9 11.02 IL4 IL5
10 10.97 IL4 IL5
11 10.89 IL4 IL5
12
Show member pathways
10.85 SFTPA2 SFTPD
13 10.84 CCL17 IL4 IL5
14 10.46 CCL17 IL4 IL5
15 10.4 IL4 IL5

GO Terms for Allergic Bronchopulmonary Aspergillosis

Cellular components related to Allergic Bronchopulmonary Aspergillosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.5 CCL17 EPX IL4 IL5 MBL2 SFTPA2
2 collagen trimer GO:0005581 9.33 MBL2 SFTPA2 SFTPD
3 clathrin-coated endocytic vesicle GO:0045334 9.32 SFTPA2 SFTPD
4 lamellar body GO:0042599 9.26 SFTPA2 SFTPD
5 extracellular space GO:0005615 9.17 CCL17 EPX IL4 IL5 MBL2 SFTPA2

Biological processes related to Allergic Bronchopulmonary Aspergillosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 toll-like receptor signaling pathway GO:0002224 9.26 SFTPA2 SFTPD
2 positive regulation of B cell proliferation GO:0030890 9.16 IL4 IL5
3 respiratory gaseous exchange GO:0007585 8.96 SFTPA2 SFTPD
4 positive regulation of phagocytosis GO:0050766 8.62 MBL2 SFTPD

Molecular functions related to Allergic Bronchopulmonary Aspergillosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 carbohydrate binding GO:0030246 9.13 MBL2 SFTPA2 SFTPD
2 cytokine activity GO:0005125 8.8 CCL17 IL4 IL5

Sources for Allergic Bronchopulmonary Aspergillosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
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70 UMLS via Orphanet
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