MCID: ALL009
MIFTS: 51

Allergic Conjunctivitis malady

Categories: Eye diseases, Immune diseases

Aliases & Classifications for Allergic Conjunctivitis

Aliases & Descriptions for Allergic Conjunctivitis:

Name: Allergic Conjunctivitis 12 14 69
Conjunctivitis, Allergic 42
Conjunctivitis Allergic 52

Classifications:



External Ids:

Disease Ontology 12 DOID:11204
MeSH 42 D003233
NCIt 47 C34506
UMLS 69 C0009766

Summaries for Allergic Conjunctivitis

Disease Ontology : 12 A chronic conjunctivitis that is an inflammation of the conjunctiva involing red, itchy, and watery eyes a resulting from an exposure to an allergen or an irritant.

MalaCards based summary : Allergic Conjunctivitis, also known as conjunctivitis, allergic, is related to allergic rhinitis and conjunctivitis. An important gene associated with Allergic Conjunctivitis is RNASE3 (Ribonuclease A Family Member 3), and among its related pathways/superpathways are Innate Immune System and TGF-Beta Pathway. The drugs Alcaftadine and Ephedrine have been mentioned in the context of this disorder. Affiliated tissues include eye, t cells and testes, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 71 Allergic conjunctivitis is inflammation of the conjunctiva (the membrane covering the white part of the... more...

Related Diseases for Allergic Conjunctivitis

Diseases related to Allergic Conjunctivitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 177)
id Related Disease Score Top Affiliating Genes
1 allergic rhinitis 11.2
2 conjunctivitis 11.0
3 pollen allergy 10.9
4 dahlberg borer newcomer syndrome 10.3 IL13 IL5
5 restrictive cardiomyopathy 10.3 IL5 RNASE3
6 peptidic growth factors deficiency 10.3 CCL11 IL5
7 aortic atherosclerosis 10.2 IL13 IL5
8 myoglobinuria recurrent 10.2 IFNG IL4
9 ileocolitis 10.2 ICAM1 IL4
10 anterior dislocation of lens 10.2 CCL11 IL4 RNASE3
11 hypercementosis 10.2 IL13 IL5
12 marasmus 10.2 IL4 IL5 RNASE3
13 papillary squamous carcinoma 10.2 IL4 IL5
14 lens-induced iridocyclitis 10.2 IL4 IL5 RNASE3
15 renal hypertension 10.2 IL13 IL5 RNASE3
16 asymptomatic neurosyphilis 10.2 IFNG IL4
17 natural killer cell leukemia 10.2 CCL11 IL5
18 brown shrimp allergy 10.2 IL5 RNASE3
19 orbit alveolar rhabdomyosarcoma 10.2 IL4 IL5 RNASE3
20 bone peripheral neuroepithelioma 10.2 IL13 IL4 IL5
21 indian plum allergy 10.2 IL13 IL4 IL5
22 lactose intolerance 10.2 IL13 IL4 IL5
23 necrotizing gastritis 10.2 CCL11 IL5 RNASE3
24 askin's tumor 10.2 IL13 IL4 IL5
25 gastroschisis abdominal wall defects, included 10.2 IFNG IL5
26 duodenal somatostatinoma 10.2 IL13 IL4 IL5
27 autosomal dominant deafness-onychodystrophy syndrome 10.2 IFNG IL4
28 disordered steroidogenesis due to cytochrome p450 oxidoreductase 10.2 CCL11 IL13 IL5
29 israeli tick typhus 10.2 IFNG IL13
30 monocytic leukemia 10.2 CCL11 IL5 RNASE3
31 hypersensitivity vasculitis 10.1 IL4 IL5
32 tungiasis 10.1 IFNG IL4
33 common peroneal nerve lesion 10.1 CXCL8 IL5
34 conidiobolomycosis 10.1 CXCL8 IL4
35 central nervous system origin vertigo 10.1 IFNG IL4 RNASE3
36 crustacean allergy 10.1 IFNG IL13 IL4
37 chromophobe adenoma 10.1 CXCL8 ICAM1
38 vestibule of mouth cancer 10.1 IL4 TLR3
39 cutaneous candidiasis 10.1 CXCL8 ICAM1
40 microglandular adenosis of breast 10.1 CCL11 CXCL8
41 exudative vitreoretinopathy 2, x-linked 10.1 IL13 IL5
42 hidradenitis suppurativa 10.1 CCL11 CXCL8
43 urethral intrinsic sphincter deficiency 10.1 IFNG IL4 IL5
44 spastic paraplegia 3a, autosomal dominant 10.1 IL13 IL4 IL5 RNASE3
45 luminal breast carcinoma 10.1 IL13 IL4 IL5 RNASE3
46 isolated klippel-feil syndrome 10.1 IFNG IL4 IL5
47 actinic keratosis 10.1 IL13 IL4 IL5 RNASE3
48 abnormal retinal correspondence 10.1 IFNG IL4 IL5
49 apricot allergy 10.1 CCL11 IL4 IL5 RNASE3
50 paralytic poliomyelitis 10.1 IFNG TLR3

Graphical network of the top 20 diseases related to Allergic Conjunctivitis:



Diseases related to Allergic Conjunctivitis

Symptoms & Phenotypes for Allergic Conjunctivitis

MGI Mouse Phenotypes related to Allergic Conjunctivitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.96 CCL11 HRH1 ICAM1 IFNG IL13 IL33
2 homeostasis/metabolism MP:0005376 9.81 HRH1 ICAM1 IFNG IL13 IL33 IL4
3 digestive/alimentary MP:0005381 9.8 IFNG IL13 IL33 IL4 IL5 ICAM1
4 immune system MP:0005387 9.65 CCL11 HRH1 ICAM1 IFNG IL13 IL33
5 respiratory system MP:0005388 9.17 CCL11 IFNG IL13 IL33 IL4 IL5

Drugs & Therapeutics for Allergic Conjunctivitis

Drugs for Allergic Conjunctivitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 158)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Alcaftadine Approved Phase 4,Phase 3 147084-10-4 19371515
2
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1 299-42-3 9294
3
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 75614-87-8, 51-45-6 774
4
Naphazoline Approved Phase 4,Phase 3 835-31-4 4436
5
Pheniramine Approved Phase 4 86-21-5 4761
6
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1 90-82-4 7028
7
Loteprednol Approved Phase 4,Phase 3,Phase 2 82034-46-6, 129260-79-3 444025 9865442
8
Glycerol Approved, Experimental Phase 4,Phase 3 56-81-5 753
9
Tacrolimus Approved, Investigational Phase 4,Phase 2,Phase 3 104987-11-3 445643 439492
10
Ketotifen Approved Phase 4,Phase 3,Phase 2,Phase 1 34580-14-8, 34580-13-7 3827
11
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 50-02-2 5743
12
Epinastine Approved, Investigational Phase 4,Phase 3 80012-43-7 3241
13
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2 83-43-2 6741
14
Prednisolone Approved, Vet_approved Phase 4,Phase 2 50-24-8 5755
15
Desloratadine Approved, Investigational Phase 4,Phase 3 100643-71-8 124087
16
Dipivefrin Approved Phase 4 52365-63-6 3105
17
Tranilast Approved, Investigational Phase 4 53902-12-8 93543
18
Cyclosporine Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 79217-60-0, 59865-13-3 5284373 6435893
19
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 22916-47-8 4189
20
Montelukast Approved Phase 4 158966-92-8 5281040
21
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
22
Tobramycin Approved, Investigational Phase 4,Phase 3 32986-56-4 5496 36294
23
Albendazole Approved, Vet_approved Phase 4 54965-21-8 2082
24
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 53477736 447043
25
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
26
Pimecrolimus Approved, Investigational Phase 4 137071-32-0 6447131 17753757
27
Maleic acid Experimental Phase 4 110-16-7 444266
28 Ophthalmic Solutions Phase 4,Phase 3,Phase 2,Phase 1
29 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1
30 Adrenergic Agents Phase 4,Phase 3,Phase 2
31 Adrenergic Agonists Phase 4,Phase 3,Phase 2
32 Adrenergic alpha-Agonists Phase 4,Phase 3,Phase 2
33 Anti-Allergic Agents Phase 4,Phase 3,Phase 2,Phase 1
34 Antipruritics Phase 4,Phase 3,Phase 2,Phase 1
35 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1
36 Histamine Antagonists Phase 4,Phase 3,Phase 2,Phase 1
37 Histamine H1 Antagonists Phase 4,Phase 3,Phase 2,Phase 1
38
Histamine Phosphate Phase 4,Phase 3,Phase 2,Phase 1 51-74-1 65513
39 Nasal Decongestants Phase 4,Phase 3,Phase 2,Phase 1
40 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
41 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1
42 Vasoconstrictor Agents Phase 4,Phase 3,Phase 2,Phase 1
43 Tetrahydrozoline Phase 4,Phase 3,Phase 2,Phase 1
44 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2
45 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
46 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
47 Bronchodilator Agents Phase 4,Phase 3
48
Fluticasone Phase 4,Phase 3 90566-53-3, 80474-14-2 62924 22833648
49 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
50 Analgesics Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 282)
id Name Status NCT ID Phase
1 Use of BEPREVE (Bepotastine Besilate Ophthalmic Solution) 1.5% for Allergic Conjunctivitis and Contact Lenses Unknown status NCT01337557 Phase 4
2 Comparison of Tolerability Between Two Allergy Drops Unknown status NCT01390961 Phase 4
3 The Effect of BEPREVE 1.5% on Tear Film Osmolarity and Tear Film Lipid Layer Unknown status NCT01346371 Phase 4
4 Ocular Allergy Treatment Practical Impact Trial Unknown status NCT01808768 Phase 4
5 Efficacy and Safety of LAIS® Mites Sublingual Tablets Unknown status NCT02277483 Phase 4
6 Effect of Fluticasone Proprionate 0.05% on Narrow Band UV-B in Active Vitiligo Unknown status NCT01246921 Phase 4
7 A Comparison of Olopatadine and Fluticasone in Patients With Allergic Conjunctivitis Completed NCT00655109 Phase 4
8 Confocal Analysis of Corneal Structures of Symptomatic Allergic Conjunctivitis Patients Completed NCT01697969 Phase 4
9 Bepreve vs. Alrex in Subjects With Moderate to Severe Allergic Conjunctivitis Completed NCT01443442 Phase 4
10 Ketotifen Ophthalmic Solution With Emedastine in Patients With Seasonal Allergic Conjunctivitis Completed NCT00133627 Phase 4
11 A Study of Patient Perception and Quality of Life Associated With the Use of Olopatadine 0.2% in Subjects With Allergic Conjunctivitis Completed NCT01272089 Phase 4
12 Assessing the Efficacy of Maxidex® and Patanol® for the Treatment of Allergic Conjunctivitis Completed NCT01119287 Phase 4
13 Effectiveness of Olopatadine HCl Ophthalmic Solution for the Treatment of Allergic Conjunctivitis in Japan Completed NCT02251613 Phase 4
14 Evaluation of the Effect and Tolerance of Preservative Free NAAGA on the Inflammatory Component and Symptoms of Dry Eye Syndrome in Allergic Conjunctivitis Patients Completed NCT01203540 Phase 4
15 Patient Perceptions and Quality of Life Associated With the Use of Olapatadine 0.2% for the Treatment of Allergic Conjunctivitis Completed NCT01159769 Phase 4
16 A Study to Evaluate the Duration of LASTACAFT® in Acute Allergic Conjunctivitis Completed NCT01470118 Phase 4
17 A Study to Evaluate the Efficacy of Lastacaft® Compared to Pataday™ and Placebo in Patients With Acute Allergic Conjunctivitis Completed NCT01732757 Phase 4
18 Non-Pharmaceutical Treatment of Seasonal Allergic Conjunctivitis Completed NCT01569191 Phase 4
19 Study of Two Marketed Ocular Anti-Allergy Medications in Subjects With Allergic Conjunctivitis Completed NCT00534794 Phase 4
20 Clinical Evaluation of 0.1% Olopatadine Hydrochloride Ophthalmic Solution in Pediatric Patients Completed NCT01109485 Phase 4
21 Patient Perception Study for AL-4943A Completed NCT01294969 Phase 4
22 Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge Model Completed NCT00689078 Phase 4
23 A Study of the Effects of Desloratadine on Conjunctival Allergen Challenge-induced Ocular Signs and Symptoms (Study P04209) Completed NCT00311844 Phase 4
24 Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model Completed NCT01534195 Phase 4
25 Assessment of Alcon's Ocular Image Quantification System Completed NCT01282138 Phase 4
26 Efficacy Investigation Study of Olopatadine Hydrochloride Ophthalmic Solution Using OHIO Chamber in Patients With Seasonal Allergic Rhinitis (SAR) Completed NCT00818805 Phase 4
27 Mast-Cell Stabilizing Effects of Olopatadine Completed NCT00389025 Phase 4
28 Study of the Effect of Fluticasone Furoate Nasal Spray on Spring Allergy Eye Symptoms Completed NCT00891436 Phase 4
29 A Single-Center Evaluation of the Anti-Inflammatory Effects of Lastacaft as Measured by In-Vivo Confocal Microscopy Completed NCT02308501 Phase 4
30 Evaluation of Prednisolone in a Modified Conjunctival Allergen Challenge Model Completed NCT01730872 Phase 4
31 An Allergen BioCube (ABC) Study Evaluating the Efficacy of Fluticasone Propionate Nasal Spray Compared to Placebo Completed NCT01439815 Phase 4
32 Topical Cyclosporine for Vernal Keratoconjunctivitis (VKC) in Rwanda Completed NCT01211327 Phase 4
33 The Evaluation of Bepreve on the Measurement of Wheal and Flare Response From Histamine Skin Prick Testing Completed NCT01128556 Phase 4
34 Montelukast as a Controller of Atopic Syndrome Completed NCT00559546 Phase 4
35 Tolerability of Grazax in Patients With Hayfever in Real Life Settings Completed NCT01433510 Phase 4
36 Study of the Clinical and Biological Efficacity of NAAXIA SINE® in Vernal Keratoconjunctivitis Completed NCT00357019 Phase 4
37 Molecular and Cellular Mechanism in Rhinitis Allergic Patients Treated With GRAZAX® Completed NCT02437786 Phase 4
38 The Impact of Grass SLIT Treatment on Birch Pollen Induced Allergic Rhinitis - a Pilot Evaluation Completed NCT02394600 Phase 4
39 Efficacy of Co-administration of Bilastine and Montelukast in Patients With SARC and Asthma Completed NCT02761252 Phase 4
40 PURETHAL Grasses Rush Study Completed NCT01059266 Phase 4
41 PURETHAL Birch RUSH Study Completed NCT01918956 Phase 4
42 Safety Study of MK-3641 and MK-7243 Co-administered in Adult Participants With Ragweed and Grass Pollen Induced Allergic Rhinitis (P08607, MK-3641-006) Completed NCT02256553 Phase 4
43 Safety and Efficacy of Zylet vs Lotemax, Tobramycin and Vehicle in Pediatric Blepharoconjunctivitis Completed NCT00705159 Phase 4
44 The Utility of in Vivo Confocal Microscopy to Assess Cellular Response and Efficacy of Long-term Topical Steroid Treatment in Patients With Dry Eye Disease Completed NCT02120079 Phase 4
45 Zylet vs TobraDex in Blepharokeratoconjunctivitis Completed NCT00447577 Phase 4
46 Multicenter, Randomized, Controlled Study of the Effect of Lotemax on Initiation of Dry Eye Treatment With Restasis Completed NCT00407043 Phase 4
47 Topical Tacrolimus in Vernal Keratoconjunctivitis Recruiting NCT02456025 Phase 4
48 Sanitation, Water, and Instruction in Face-washing for Trachoma Recruiting NCT02754583 Phase 4
49 A Study to Evaluate the Safety and Efficacy of Lotemax Ophthalmic Suspension 0.5% Active, not recruiting NCT01437982 Phase 4
50 Alleviation of Cedar Pollen Induced Allergic Symptoms by Orally Taken Superfine Beta-1,3-Glucan Terminated NCT00276445 Phase 4

Search NIH Clinical Center for Allergic Conjunctivitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: conjunctivitis, allergic

Genetic Tests for Allergic Conjunctivitis

Anatomical Context for Allergic Conjunctivitis

MalaCards organs/tissues related to Allergic Conjunctivitis:

39
Eye, T Cells, Testes, Monocytes, Endothelial, B Cells, Lymph Node

Publications for Allergic Conjunctivitis

Articles related to Allergic Conjunctivitis:

(show top 50) (show all 575)
id Title Authors Year
1
Diagnosis and management of allergic conjunctivitis in pediatric patients. ( 28052798 )
2017
2
Effects of Exposure to Ozone on the Ocular Surface in an Experimental Model of Allergic Conjunctivitis. ( 28046113 )
2017
3
Role of CCL7 in Type I Hypersensitivity Reactions in Murine Experimental Allergic Conjunctivitis. ( 27956527 )
2017
4
Self-Reported Allergic Rhinitis and/or Allergic Conjunctivitis Associate with IL13 rs20541 Polymorphism in Finnish Adult Asthma Patients. ( 28273659 )
2017
5
Redness response phenotypes of allergic conjunctivitis in an allergen challenge chamber. ( 28007090 )
2017
6
Superoxide dismutase 3 attenuates experimental Th2-driven allergic conjunctivitis. ( 28063939 )
2017
7
Efficacy and safety of an eye wash solution in allergic conjunctivitis after conjunctival allergen challenge. ( 27788889 )
2016
8
Expression of TSLP and Downstream Molecules IL-4, IL-5, and IL-13 on the Eye Surface of Patients with Various Types of Allergic Conjunctivitis. ( 27504196 )
2016
9
High incidence of dry eye in young children with allergic conjunctivitis in Southwest China. ( 27226346 )
2016
10
Ocular Pharmacology of Tear Film, Dry Eye, and Allergic Conjunctivitis. ( 27913889 )
2016
11
Development of Allergic Conjunctivitis Induced by House Dust Mite Extract From Dermatophagoides pteronyssinus. ( 27074380 )
2016
12
TRPV1 Antagonist Suppresses Allergic Conjunctivitis in a Murine Model. ( 27726468 )
2016
13
Treating allergic conjunctivitis: A once-daily medication that provides 24-hour symptom relief. ( 27466061 )
2016
14
Topical Application of Interleukin-28A Attenuates Allergic Conjunctivitis in an Ovalbumin-Induced Mouse Model. ( 26886894 )
2016
15
Allergic Conjunctivitis and the Associated Risk of Migraine Among Children: A Nationwide Population-based Cohort Study. ( 27382919 )
2016
16
Topical Olopatadine in the Treatment of Allergic Conjunctivitis: A Systematic Review and Meta-analysis. ( 27192186 )
2016
17
Topical Administration of I^-1,3-Glucan to Modulate Allergic Conjunctivitis in a Murine Model. ( 27002295 )
2016
18
Risk of Allergic Rhinitis, Allergic Conjunctivitis, and Eczema in Children Born to Mothers with Gum Inflammation during Pregnancy. ( 27224053 )
2016
19
Ocular itch associated with allergic conjunctivitis: latest evidence and clinical management. ( 26770669 )
2016
20
Topical Antihistamines and Mast Cell Stabilizers for Treating Allergic Conjunctivitis. ( 27281835 )
2016
21
Ambient air pollution, weather changes, and outpatient visits for allergic conjunctivitis: A retrospective registry study. ( 27033635 )
2016
22
Evaluating the efficacy of epinastine ophthalmic solution using a conjunctivitis allergen challenge model in patients with birch pollen allergic conjunctivitis. ( 27720602 )
2016
23
Efficacy of olopatadine hydrochloride 0.1%, emedastine difumarate 0.05%, and loteprednol etabonate 0.5% for Chinese children with seasonal allergic conjunctivitis: a randomized vehicle-controlled study. ( 27869354 )
2016
24
Treatment with olopatadine and naphazoline hydrochloride reduces allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF. ( 26936233 )
2016
25
Biomimetic contact lenses eluting olopatadine for allergic conjunctivitis. ( 27221794 )
2016
26
Efficacy and safety of olopatadine hydrochloride 0.77% in patients with allergic conjunctivitis using a conjunctival allergen-challenge model. ( 26392751 )
2015
27
Advances in pharmacotherapy for allergic conjunctivitis. ( 25943976 )
2015
28
Estimating Seasonal Allergic Conjunctivitis Market Size And Spending. ( 26532791 )
2015
29
Oxidative stress parameters and serum magnesium levels in patients with seasonal allergic conjunctivitis. ( 26555509 )
2015
30
Topical Fluorometholone Versus Diclofenac Sodium in Cases With Perennial Allergic Conjunctivitis. ( 26322818 )
2015
31
Roles of Epithelial Cell-Derived Type 2-Initiating Cytokines in Experimental Allergic Conjunctivitis. ( 26244295 )
2015
32
Epidemiology of allergic conjunctivitis: clinical appearance and treatment patterns in a population-based study. ( 26258920 )
2015
33
Topical antihistamines and mast cell stabilisers for treating seasonal and perennial allergic conjunctivitis. ( 26028608 )
2015
34
Possible Mechanism of Action of the Antiallergic Effect of an Aqueous Extract of Heliotropium indicum L. in Ovalbumin-Induced Allergic Conjunctivitis. ( 26681960 )
2015
35
Does allergic conjunctivitis always require prescription eyedrops? ( 26651889 )
2015
36
Allergic conjunctivitis: a cross-sectional study. ( 25809830 )
2015
37
Down-Regulation of miR-146a Expression Induces Allergic Conjunctivitis in Mice by Increasing TSLP Level. ( 26166175 )
2015
38
Efficacy of topical application of 0.03% tacrolimus eye ointment in the management of allergic conjunctivitis. ( 26604594 )
2015
39
Prevalence of allergic conjunctivitis among basic school children in the Kumasi Metropolis (Ghana): a community-based cross-sectional study. ( 26134507 )
2015
40
Loteprednol etabonate in the treatment of allergic conjunctivitis: a meta-analysis. ( 26039179 )
2015
41
Culture medium from TNF-I+-stimulated mesenchymal stem cells attenuates allergic conjunctivitis through multiple antiallergic mechanisms. ( 25652765 )
2015
42
Correction: Role of Macrophage Migration Inhibitory Factor (MIF) in Pollen-Induced Allergic Conjunctivitis and Pollen Dermatitis in Mice. ( 25789999 )
2015
43
The C-C chemokine receptor 6 (CCR6) is crucial for Th2-driven allergic conjunctivitis. ( 26307432 )
2015
44
Effect of alcaftadine 0.25% on ocular itch associated with seasonal or perennial allergic conjunctivitis: a pooled analysis of two multicenter randomized clinical trials. ( 25999684 )
2015
45
Consensus document on allergic conjunctivitis (DECA). ( 25997302 )
2015
46
Prevention of allergic conjunctivitis in mice by a rice-based edible vaccine containing modified Japanese cedar pollen allergens. ( 25563761 )
2015
47
Phase 3 Randomized Double-Masked Study of Efficacy and Safety of Once-Daily 0.77% Olopatadine Hydrochloride Ophthalmic Solution in Subjects With Allergic Conjunctivitis Using the Conjunctival Allergen Challenge Model. ( 26266427 )
2015
48
Semaphorin 3A controls allergic and inflammatory responses in experimental allergic conjunctivitis. ( 25709899 )
2015
49
Combination treatment for allergic conjunctivitis - Plant derived histidine decarboxylase inhibitor and H1 antihistaminic drug. ( 26028180 )
2015
50
Allergic conjunctivitis: Time for a new classification. ( 26108075 )
2015

Variations for Allergic Conjunctivitis

Expression for Allergic Conjunctivitis

Search GEO for disease gene expression data for Allergic Conjunctivitis.

Pathways for Allergic Conjunctivitis

Pathways related to Allergic Conjunctivitis according to GeneCards Suite gene sharing:

(show all 37)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.89 CCL11 CXCL8 ICAM1 IFNG IL13 IL33
2
Show member pathways
13.42 CCL11 CXCL8 ICAM1 IFNG IL13 IL4
3
Show member pathways
13.28 CCL11 CXCL8 IL13 IL4 IL5 TLR3
4
Show member pathways
13.26 CCL11 CXCL8 ICAM1 IFNG IL13 IL33
5
Show member pathways
12.71 CXCL8 ICAM1 IFNG IL13 IL33 IL4
6
Show member pathways
12.66 CCL11 CXCL8 ICAM1 IFNG IL13 IL4
7
Show member pathways
12.49 IFNG IL13 IL4 IL5
8
Show member pathways
12.21 CCL11 CXCL8 IFNG IL13 IL4 IL5
9
Show member pathways
12.15 IFNG IL13 IL4 IL5
10
Show member pathways
12.14 CXCL8 IFNG TLR3
11
Show member pathways
12.12 CCL11 CXCL8 IFNG IL4
12
Show member pathways
12.12 CXCL8 IFNG IL13 IL4 IL5
13 11.96 CXCL8 ICAM1 IFNG IL4
14 11.95 IFNG IL4 IL5 PTGDR2
15 11.95 CCL11 CXCL8 ICAM1 IL13 IL4
16
Show member pathways
11.93 IL13 IL5 TLR3
17
Show member pathways
11.84 IFNG IL4 TLR3
18 11.78 CXCL8 ICAM1 IFNG
19
Show member pathways
11.74 CXCL8 IFNG IL4 IL5
20 11.66 ICAM1 IL4 IL5
21 11.61 CCL11 IL4 IL5
22
Show member pathways
11.6 CXCL8 ICAM1 IFNG
23 11.57 CCL11 CXCL8 IL13 IL4 IL5
24 11.55 CXCL8 ICAM1 IFNG IL13 IL4 IL5
25 11.52 CXCL8 ICAM1 IL13 IL4
26 11.49 CXCL8 ICAM1 IFNG
27 11.44 CXCL8 ICAM1 IFNG
28 11.34 IFNG IL13 IL33 IL4 IL5 PTGDR2
29 11.29 IFNG IL4 IL5
30 11.23 IFNG IL13 IL4 IL5
31 11.16 CCL11 CXCL8 IL13 IL4 IL5
32 11.16 IFNG IL13 IL33 IL4 IL5
33 11.15 IFNG IL13 IL4 IL5
34 11.12 IFNG IL13
35 11.06 ICAM1 IFNG
36 10.92 IL13 IL4 IL5
37 10.77 CCL11 IFNG IL13 IL33 IL4 IL5

GO Terms for Allergic Conjunctivitis

Cellular components related to Allergic Conjunctivitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 CCL11 CXCL8 IFNG IL13 IL33 IL4
2 external side of plasma membrane GO:0009897 9.46 ICAM1 IFNG IL13 IL4
3 extracellular space GO:0005615 9.28 CCL11 CXCL8 ICAM1 IFNG IL13 IL33

Biological processes related to Allergic Conjunctivitis according to GeneCards Suite gene sharing:

(show all 35)
id Name GO ID Score Top Affiliating Genes
1 defense response to virus GO:0051607 9.84 IFNG IL33 TLR3
2 positive regulation of protein phosphorylation GO:0001934 9.83 IFNG IL4 TLR3
3 cellular response to lipopolysaccharide GO:0071222 9.82 CXCL8 ICAM1 IFNG
4 response to ethanol GO:0045471 9.81 ICAM1 IL13 IL4
5 cellular response to tumor necrosis factor GO:0071356 9.81 CCL11 CXCL8 ICAM1
6 response to virus GO:0009615 9.8 CCL11 IFNG TLR3
7 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.77 ICAM1 IL4 IL5
8 movement of cell or subcellular component GO:0006928 9.76 CXCL8 IFNG IL13
9 cellular response to interleukin-1 GO:0071347 9.73 CCL11 CXCL8 ICAM1
10 neutrophil chemotaxis GO:0030593 9.71 CCL11 CXCL8 IFNG
11 chemotaxis GO:0006935 9.71 CCL11 CXCL8 IL4 PTGDR2
12 cellular response to interferon-gamma GO:0071346 9.69 CCL11 ICAM1 TLR3
13 positive regulation of interleukin-12 production GO:0032735 9.66 IFNG TLR3
14 innate immune response in mucosa GO:0002227 9.66 IL4 RNASE3
15 negative regulation of osteoclast differentiation GO:0045671 9.65 IL4 TLR3
16 defense response to protozoan GO:0042832 9.65 IFNG IL4
17 extrinsic apoptotic signaling pathway GO:0097191 9.65 IFNG IL33 TLR3
18 positive regulation of macrophage activation GO:0043032 9.62 IL13 IL33
19 positive regulation of immunoglobulin secretion GO:0051024 9.62 IL33 IL5
20 positive regulation of isotype switching to IgG isotypes GO:0048304 9.61 IFNG IL4
21 positive regulation of mast cell degranulation GO:0043306 9.61 IL13 IL4
22 eosinophil chemotaxis GO:0048245 9.59 CCL11 HRH1
23 positive regulation of interleukin-13 production GO:0032736 9.58 IL33 IL4
24 positive regulation of MHC class II biosynthetic process GO:0045348 9.57 IFNG IL4
25 positive regulation of immunoglobulin production GO:0002639 9.55 IL13 IL4
26 positive regulation of B cell proliferation GO:0030890 9.54 IL13 IL4 IL5
27 type 2 immune response GO:0042092 9.52 IL33 IL4
28 negative regulation of endothelial cell apoptotic process GO:2000352 9.5 ICAM1 IL13 IL4
29 regulation of proton transport GO:0010155 9.49 IL13 IL4
30 negative regulation of complement-dependent cytotoxicity GO:1903660 9.46 IL13 IL4
31 microglial cell activation involved in immune response GO:0002282 9.43 IL33 TLR3
32 microglial cell activation GO:0001774 9.43 IL13 IL4 TLR3
33 inflammatory response GO:0006954 9.43 CCL11 CXCL8 HRH1 IL13 IL5 TLR3
34 positive regulation of chemokine biosynthetic process GO:0045080 9.33 IFNG IL4 TLR3
35 immune response GO:0006955 9.17 CCL11 CXCL8 IFNG IL13 IL4 IL5

Molecular functions related to Allergic Conjunctivitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.17 CCL11 CXCL8 IFNG IL13 IL33 IL4
2 cytokine receptor binding GO:0005126 8.96 IL13 IL4

Sources for Allergic Conjunctivitis

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