MCID: ALL010
MIFTS: 57

Allergic Contact Dermatitis malady

Categories: Skin diseases, Immune diseases

Aliases & Classifications for Allergic Contact Dermatitis

Summaries for Allergic Contact Dermatitis

Disease Ontology : 12 A contact dermititis that is an allergic skin reaction to foreign chemical or substances leading to red, itchy, weepy reaction where the skin has come into contact with a substance that the immune system recognizes as foreign.

MalaCards based summary : Allergic Contact Dermatitis, also known as dermatitis, allergic contact, is related to rosacea and choroiditis. An important gene associated with Allergic Contact Dermatitis is IL31 (Interleukin 31), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Hydrocortisone and Sodium thiosulfate have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and t cells, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and hematopoietic system

Wikipedia : 71 Allergic contact dermatitis (ACD) is a form of contact dermatitis that is the manifestation of an... more...

Related Diseases for Allergic Contact Dermatitis

Diseases related to Allergic Contact Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 353)
id Related Disease Score Top Affiliating Genes
1 rosacea 30.0 IFNG IL10 IL1B SELE
2 choroiditis 29.5 CXCL8 IL10 IL1B TNF
3 burns 29.3 CXCL8 CXCR3 IFNG IL10 IL17A TNF
4 allergic contact dermatitis of eyelid 12.2
5 occupational dermatitis 11.5
6 dermatitis 11.2
7 contact dermatitis 11.2
8 pyridoxal 5'-phosphate-dependent epilepsy 10.3 IL10 TNF
9 atopic dermatitis 10.3
10 latent syphilis 10.3 CXCR3 ICAM1 IL5
11 right ventricle hypoplasia 10.3 ICAM1 SELE TNF
12 dermatomycosis 10.3 ICAM1 SELE TNF
13 renal hypertension 10.3 CCL17 CXCR3 IL5
14 gastroschisis abdominal wall defects, included 10.3 IFNG IL5
15 dracunculiasis 10.2 ICAM1 SELE TNF
16 severe combined immunodeficiency, t cell-negative, b-cell/natural killer-cell positive 10.2 IFNG IL10 TNF
17 erythema multiforme 10.2
18 psoriasis 10.2
19 persistent mullerian duct syndrome 10.2 ICAM1 IL10 TNF
20 intussusception 10.2 IL1B TNF
21 pancreatic signet ring cell adenocarcinoma 10.2 IFNG IL10 TNF
22 pulpitis 10.2 IFNG IL10 TNF
23 myoglobinuria recurrent 10.2 IFNG IL4
24 idiopathic hypertrophic pachymeningitis 10.2 IL10 IL33 TNF
25 periodontosis 10.2 ICAM1 IFNG TNF
26 hereditary alpha tryptasemia syndrome 10.2 IFNG IL10 TNF
27 hepatitis 10.2 IFNG IL10 TNF
28 pemphigus vulgaris, familial 10.2 ICAM1 SELE TNF
29 multiple mitochondrial dysfunctions syndrome 10.2 IFNG IL10 IL5
30 aniseikonia 10.2 IFNG IL17A TNF
31 smooth muscle tumor 10.2 CXCR3 IL17A IL5
32 plummer's disease 10.2 IFNG IL10 TNF
33 chronic thromboembolic pulmonary hypertension 10.2 IFNG IL10 SELE
34 powassan encephalitis 10.2 CXCR3 ICAM1 SELE TNF
35 radial hypoplasia, triphalangeal thumbs and hypospadias 10.2 CXCR3 IL5 SELE TNF
36 heart conduction disease 10.2 IFNG IL10 TNF
37 retinal ischemia 10.2 CXCR3 ICAM1 IFNG TNF
38 chromophobe adenoma 10.2 CXCL8 ICAM1
39 autosomal dominant deafness-onychodystrophy syndrome 10.2 IFNG IL4 TNF
40 sparganosis 10.2 ICAM1 IL4 SELE
41 tubular renal disease-cardiomyopathy syndrome 10.2 IL10 IL4 TNF
42 tonsil cancer 10.2 ICAM1 SELE
43 causalgia 10.2 CXCR3 IFNG IL10
44 pseudo-meigs syndrome 10.2 FLG IL10 TNF
45 lagophthalmos 10.2 IL10 IL4 TNF
46 esophagus lymphoma 10.2 CXCL8 IFNG TNF
47 clostridium difficile colitis 10.2 IFNG IL4 TNF
48 cutaneous candidiasis 10.1 CXCL8 ICAM1
49 multiple epiphyseal dysplasia due to collagen 9 anomaly 10.1 IFNG IL4 IL5
50 astrocytoma 10.1 CCL17 IL10 IL5 TNF

Graphical network of the top 20 diseases related to Allergic Contact Dermatitis:



Diseases related to Allergic Contact Dermatitis

Symptoms & Phenotypes for Allergic Contact Dermatitis

GenomeRNAi Phenotypes related to Allergic Contact Dermatitis according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.4 IL17A IL1B TNF CXCL8 ICAM1 IL10
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.4 IL17A IL1B TNF CXCL8 ICAM1 IL10

MGI Mouse Phenotypes related to Allergic Contact Dermatitis:

44 (show all 11)
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.25 IL5 SELE TNF CCL17 CD4 CXCR3
2 cellular MP:0005384 10.19 CCL17 CD4 CXCR3 ICAM1 IFNG IL10
3 homeostasis/metabolism MP:0005376 10.18 IL1B IL33 IL4 IL5 SELE TNF
4 immune system MP:0005387 10.18 CCL17 CD4 CXCR3 ICAM1 IFNG IL10
5 digestive/alimentary MP:0005381 10.13 IL17A IL33 IL4 IL5 TNF CD4
6 endocrine/exocrine gland MP:0005379 10.06 IL33 IL4 TNF CD4 ICAM1 IFNG
7 mortality/aging MP:0010768 10 CD4 CXCR3 ICAM1 IFNG IL10 IL17A
8 integument MP:0010771 9.97 CD4 ICAM1 IFNG IL10 IL1B IL33
9 neoplasm MP:0002006 9.7 CXCR3 ICAM1 IFNG IL10 IL1B IL5
10 no phenotypic analysis MP:0003012 9.5 CD4 IFNG IL10 IL17A IL33 IL4
11 respiratory system MP:0005388 9.28 CXCR3 IFNG IL10 IL17A IL33 IL4

Drugs & Therapeutics for Allergic Contact Dermatitis

Drugs for Allergic Contact Dermatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 168)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754 657311
2 Sodium thiosulfate Approved Phase 4
3
Fluocinonide Approved, Investigational Phase 4 356-12-7 9642
4
Bacitracin Approved, Vet_approved Phase 4,Phase 2 1405-87-4 439542 10909430
5
Petrolatum Approved Phase 4,Phase 3 8009-03-8
6
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492
7
Adapalene Approved Phase 4 106685-40-9 60164
8
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
9
Benzoyl peroxide Approved Phase 4 94-36-0 7187
10
Ethanol Approved Phase 4 64-17-5 702
11
Dapsone Approved, Investigational Phase 4 80-08-0 2955
12 Titanium dioxide Approved Phase 4 13463-67-7
13
leucovorin Approved, Nutraceutical Phase 4 58-05-9 54575, 6560146 143
14
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
15
Butyric Acid Experimental Phase 4 107-92-6 264
16 Parthenolide Phase 4,Phase 2 20554-84-1
17 Analgesics Phase 4,Phase 2
18 glucocorticoids Phase 4,Phase 3,Phase 1
19 Chelating Agents Phase 4
20 Cortisol succinate Phase 4
21 Gold Sodium Thiosulfate Phase 4
22 Analgesics, Non-Narcotic Phase 4,Phase 2
23 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1
24 Hormone Antagonists Phase 4,Phase 3,Phase 1
25 Hormones Phase 4,Phase 3,Phase 1
26 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
27 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 1
28 Hydrocortisone 17-butyrate 21-propionate Phase 4
29 Hydrocortisone acetate Phase 4
30 Hydrocortisone-17-butyrate Phase 4
31 Anti-Allergic Agents Phase 4,Phase 3,Phase 2
32 Anti-Asthmatic Agents Phase 4
33 Anti-Bacterial Agents Phase 4,Phase 2
34 Anti-Infective Agents Phase 4,Phase 3,Phase 2
35 Protective Agents Phase 4,Phase 1
36 Antidotes Phase 4
37 Anti-Infective Agents, Local Phase 4,Phase 3,Phase 2
38 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
39 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 2
40 Respiratory System Agents Phase 4,Phase 2
41 Antirheumatic Agents Phase 4,Phase 2
42 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
43 Antitubercular Agents Phase 4
44 Bronopol Phase 4
45 Antioxidants Phase 4
46
Fluticasone Phase 4 90566-53-3, 80474-14-2 62924 22833648
47 Adapalene, Benzoyl Peroxide Drug Combination Phase 4
48 Clindamycin palmitate Phase 4
49 Clindamycin phosphate Phase 4
50 Povidone Phase 4

Interventional clinical trials:

(show top 50) (show all 84)
id Name Status NCT ID Phase
1 Clinical Evaluation of T.R.U.E. Test Allergens in Children an Adolescents Unknown status NCT01797562 Phase 4
2 Quaternium-15, Use Test Unknown status NCT00311454 Phase 4
3 VANOS Cream and Skin Barrier Function Unknown status NCT00819507 Phase 4
4 Study of the Safety and Efficacy of Tacrolimus Ointment in Treating Chronic Allergic Contact Dermatitis Completed NCT00667056 Phase 4
5 Bioequivalence of Ethylenediamine Dihydrochloride Study Completed NCT01798589 Phase 4
6 A Comparative Study of the Tolerability of Two Combination Therapies for the Treatment of Acne Completed NCT00887484 Phase 4
7 A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Facial Acne Completed NCT00964223 Phase 4
8 Clinical Evaluation of T.R.U.E. TEST in Children and Adolescents Completed NCT00795951 Phase 4
9 Dermacyd Infantile (Lactic Acid)- Compatibility. Completed NCT00881374 Phase 4
10 Protopic Ointment in Children Atopic Eczema Completed NCT00689832 Phase 4
11 Protopic Ointment in Adult Atopic Eczema of the Face Completed NCT00690105 Phase 4
12 Mometasone Furoate Cream Reduces Acute Radiation Dermatitis in Head and Neck Squamous Cell Carcinomas' Patients Recruiting NCT02495064 Phase 4
13 Clinical Utility Of Genetic Screening For HLA-B*1301, On Susceptibility To Dapsone Hypersensitivity Syndrome Recruiting NCT02550080 Phase 4
14 Randomized Study for Effectiveness and Safety Evaluation of Dexamethasone 0.5 mg + Fumarate Clemastine 1 mg Compared to Dexamethasone 0.5 mg in Patients With Allergic Dermatitis Unknown status NCT01239719 Phase 3
15 Effectiveness of Clemastine Fumarate + Dexamethasone Compared to Dexchlorpheniramine Maleate in Eczema Treatment Unknown status NCT01257061 Phase 3
16 A Trial Comparing the Efficacy and Safety of Open Dressing With Petrolatum Jelly vs. Standard Gauze Dressing With Silver Sulfadiazine Completed NCT02109718 Phase 3
17 Anti-IL-17 a New Treatment for Contact Dermatititis Recruiting NCT02778711 Phase 3
18 Allergic Rhinitis, Immunotherapy and Vitamin d Recruiting NCT02738619 Phase 2, Phase 3
19 Trial of Vitamin D Supplementation in Cape Town Primary Schoolchildren Recruiting NCT02880982 Phase 3
20 Efficacy and Safety Comparing 5% Monoxidil Milky Lotion Versus 5% Minoxidil Solution in Androgenetic Alopecia Unknown status NCT01650272 Phase 1, Phase 2
21 Study of the Intradermal Injection of rHuPH20 or Placebo in Subjects With Nickel Allergic Contact Dermatitis Completed NCT00928447 Phase 2
22 Clinical Evaluation of the 3 Allergens: Methyldibromoglutharonitrile, Parthenolide and Goldnatriumthiosulphate Completed NCT00133341 Phase 2
23 Clinical Evaluation of Bacitracin Completed NCT00132600 Phase 2
24 Safety, Tolerability, and Efficacy of 21 Days Dermal Application of MRX-6 on Mild to Moderate Contact Dermatitis Completed NCT00867607 Phase 1, Phase 2
25 Study of Apremilast in Atopic or Contact Dermatitis Completed NCT00931242 Phase 2
26 Beginning Assessment of Cutaneous Treatment Efficacy of Roseomonas in Atopic Dermatitis Recruiting NCT03018275 Phase 1, Phase 2
27 Clinical Evaluation of Metal Panel Allergens: Dose Response Study Not yet recruiting NCT02615249 Phase 2
28 Xia Shi Surgical Treatment for Eczema Multi-center Clinical Research Not yet recruiting NCT02517957 Phase 2
29 NI-0801 in Allergic Contact Dermatitis Completed NCT01244607 Phase 1
30 CP-481,715 Nickel Allergy Study. Completed NCT00141180 Phase 1
31 Effect of RANKL Inhibition on UV-induced Immunosuppression Completed NCT01978483 Phase 1
32 Clinical Evaluation of the Photoallergy Potential of Xenaderm Ointment Completed NCT00645164 Phase 1
33 NatrOVA Photoallergy Study - NatrOVA Creme Rinse in Healthy Volunteers Completed NCT00605956 Phase 1
34 Clinical Evaluation of the Photoallergy Potential of Atralin Gel Completed NCT00603772 Phase 1
35 Assess Itch Behavior in Nickel Sulphate Sensitized Volunteers Completed NCT01529320 Phase 1
36 Evaluation of Safety and Efficacy of BBI-2000 in Treating and Preventing Contact Dermatitis Active, not recruiting NCT03089775 Phase 1
37 Pathophysiological Study of Allergic Contact Dermatitis to Para-Phenylenediamine (PPD). Analysis of Cellular and Molecular Targets in Skin Inflammation Unknown status NCT00445029
38 Nickel Desensitization Using Topical Therapy Unknown status NCT01413477
39 A Randomised Clinical Trial in a Population of Health Care Workers With Hand Eczema Unknown status NCT01012453
40 Evaluation of Irritancy/Allergic Sensitivity to Natural Personal-care Products by Patch Tests Unknown status NCT01816542
41 PF and FeNO and Clinical Characteristics in Children Being Diagnosed Due to Suspicion of Allergic Diseases Unknown status NCT01805635
42 Tree Nuts Allergies: Does a Single Nut Allergy Necessitate the Dietary Eviction of Other Tree Nuts? Unknown status NCT01744990
43 Inhibitory Receptors in Eosinophils of Atopic Subjects Unknown status NCT01489293
44 Cow's Milk Allergy and Functional Gastrointestinal Disorders Unknown status NCT01901380
45 Intervention Study to Evaluate the Importance of Information Given to Patients With Contact Allergy Completed NCT01953380
46 Contact Allergies to Dental Metal as a Possible Risk Factor for Oral Cancer Completed NCT00693550
47 Evaluating for Contact Allergies in Patients With Chronic Urticaria Completed NCT00868036
48 Epidemiology and Co-Reactivity of Novel Surfactant Allergens Completed NCT02534441
49 Evaluation of Tetrix Cream in the Healing of Injured Skin in Subjects With Contact Dermatitis Completed NCT00643214
50 Cumulative Irritation Patch Test Completed NCT01842711

Search NIH Clinical Center for Allergic Contact Dermatitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: dermatitis, allergic contact

Genetic Tests for Allergic Contact Dermatitis

Anatomical Context for Allergic Contact Dermatitis

MalaCards organs/tissues related to Allergic Contact Dermatitis:

39
Skin, Testes, T Cells, Eye, Monocytes, Endothelial, Tongue

Publications for Allergic Contact Dermatitis

Articles related to Allergic Contact Dermatitis:

(show top 50) (show all 684)
id Title Authors Year
1
Diagnosis and management of allergic contact dermatitis in children: common allergens that can be easily missed. ( 28525402 )
2017
2
Allergic Contact Dermatitis to 3-o-Ethyl-L-Ascorbic Acid in Skin-lightening Cosmetics. ( 28002235 )
2017
3
Occupational allergic contact dermatitis caused by benzisothiazolinone in printing ink and soap. ( 27957753 )
2017
4
Allergic contact dermatitis caused by exfoliating socks. ( 27957756 )
2017
5
Allergic Contact Dermatitis Due to Methylisothiazolinone in a Young Girl's Laundry Detergent. ( 28523864 )
2017
6
Occupational allergic contact dermatitis caused by tetracaine in an otorhinolaryngologist. ( 27957755 )
2017
7
Occupational Allergic Contact Dermatitis due to Multiple Tropical Plant Species. ( 28529083 )
2017
8
Allergic contact dermatitis caused by efinaconazole: positive patch test reactions up to 0.1% pet. ( 27957750 )
2017
9
Allergic Contact Dermatitis. ( 27886903 )
2017
10
The "Jewelry Addict": Allergic Contact Dermatitis from Repetitive Multiple Children's Jewelry Exposures. ( 27001330 )
2016
11
GPR91 deficiency exacerbates allergic contact dermatitis while reducing arthritic disease in mice. ( 27527650 )
2016
12
Allergic contact dermatitis to balsam of Peru. ( 27499544 )
2016
13
As in Atopic Dermatitis, Nonlesional Skin inA Allergic Contact Dermatitis Displays Abnormalities in Barrier Function and Ceramide Content. ( 27826010 )
2016
14
Allergic contact dermatitis caused by cocamide diethanolamine. ( 27144883 )
2016
15
Herpetol ameliorates allergic contact dermatitis through regulating T-lymphocytes. ( 27588913 )
2016
16
Patch Testing in Children and Adolescents With Suspected Allergic Contact Dermatitis. ( 27784513 )
2016
17
Allergic Contact Dermatitis from Topical Acyclovir: Case Series. ( 27658557 )
2016
18
Allergic Contact Dermatitis Caused by P-Tert-Butylphenol-Formaldehyde Resin in Orthopedic Braces. ( 27071627 )
2016
19
Allergic contact dermatitis caused by phenylethyl resorcinol, a skin-lightening agent contained in a sunscreen. ( 27620125 )
2016
20
Allergic contact dermatitis to parthenolide. ( 27161148 )
2016
21
Airborne allergic contact dermatitis caused by a henna stone. ( 27480518 )
2016
22
Influence of vitamin C on the elicitation of allergic contact dermatitis to p-phenylenediamine. ( 27027508 )
2016
23
Patch tests with commercial hair dye products in patients with allergic contact dermatitis to para-phenylenediamine. ( 27451929 )
2016
24
Allergic contact dermatitis: Patient diagnosis and evaluation. ( 27185421 )
2016
25
Effectiveness of the European Chromium VI Directive for cement implementation on occupational allergic contact dermatitis occurrence: Assessment in France and UK. ( 28008593 )
2016
26
Allergic contact dermatitis caused by the tea tree oil-containing hydrogel Burnshield(Ar). ( 27040879 )
2016
27
Hair-care practices in African American women: potential for allergic contact dermatitis. ( 27918002 )
2016
28
Anogenital allergic contact dermatitis caused by methylchloroisothiazolinone, methylisothiazolinone and topical clotrimazole with subsequent generalized exanthem triggered by oral fluconazole. ( 27040872 )
2016
29
Leather Contains Cobalt and Poses a Risk of Allergic Contact Dermatitis: Cobalt Indicator Solution and X-ray Florescence Spectrometry as Screening Tests. ( 27427822 )
2016
30
Octylisothiazolinone, an additional cause of allergic contact dermatitis caused by leather: case series and potential implications for the study of cross-reactivity with methylisothiazolinone. ( 27538353 )
2016
31
Has the epidemic of allergic contact dermatitis due to Methylisothiazolinone reached its peak? ( 27579576 )
2016
32
Allergic contact dermatitis from acrylic nails in a flamenco guitarist. ( 27834227 )
2016
33
Propolis, Colophony, and Fragrance Cross-Reactivity and Allergic Contact Dermatitis. ( 27172306 )
2016
34
Roseotoxin B Improves Allergic Contact Dermatitis through a Unique Anti-inflammatory Mechanism Involving Excessive Activation of Autophagy in Activated T-Lymphocytes. ( 27155460 )
2016
35
Diclofenac-Induced Allergic Contact Dermatitis: A Series of Four Patients. ( 27882527 )
2016
36
Allergic contact dermatitis caused by VEA(Ar) lipogel: compound allergy? ( 27620121 )
2016
37
Occupational allergic contact dermatitis in a 2-year follow-up study: how well does the patient remember the result of patch testing? ( 27102974 )
2016
38
Allergic contact dermatitis caused by copper. ( 27480515 )
2016
39
Allergic contact dermatitis caused by latex gloves in a dental undergraduate student. ( 27620128 )
2016
40
Allergic contact dermatitis caused by Dermabond(Ar). ( 27620119 )
2016
41
Mast Cells Limit the Exacerbation of Chronic Allergic Contact Dermatitis in Response to Repeated Allergen Exposure. ( 27807191 )
2016
42
Vitamin D in atopic dermatitis, chronic urticaria and allergic contact dermatitis. ( 27014952 )
2016
43
Allergic contact dermatitis caused by insect repellent wipes. ( 27040871 )
2016
44
Allergic contact dermatitis caused by topical sirolimus used as an adjuvant for laser treatment of port wine stains. ( 27480514 )
2016
45
Allergic Contact Dermatitis Due to Capryloyl Salicylic Acid. ( 27154246 )
2016
46
Sensitization to and allergic contact dermatitis caused by Mirvaso(Ar) (brimonidine tartrate) for treatment of rosacea - 2 cases. ( 27133629 )
2016
47
Occupational allergic contact dermatitis caused by heroin (diacetylmorphine) and morphine. ( 27040874 )
2016
48
The burden of allergic contact dermatitis caused by acrylates. ( 27480513 )
2016
49
Allergic contact dermatitis: Patient management and education. ( 27185422 )
2016
50
Activation of Tryptophan and Phenylalanine Catabolism in the Remission Phase of Allergic Contact Dermatitis: A Pilot Study. ( 27771694 )
2016

Variations for Allergic Contact Dermatitis

Expression for Allergic Contact Dermatitis

Search GEO for disease gene expression data for Allergic Contact Dermatitis.

Pathways for Allergic Contact Dermatitis

Pathways related to Allergic Contact Dermatitis according to GeneCards Suite gene sharing:

(show top 50) (show all 72)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
14.07 CD4 CXCL8 ICAM1 IFNG IL10 IL17A
2
Show member pathways
13.89 CCL17 CD4 CXCL8 CXCR3 IL10 IL17A
3
Show member pathways
13.73 CCL17 CD4 CXCL8 CXCR3 IFNG IL10
4
Show member pathways
13.61 CCL17 CD4 CXCL8 ICAM1 IFNG IL10
5
Show member pathways
13.49 CCL17 CD4 CXCL8 CXCR3 IL10 IL17A
6
Show member pathways
13.41 CD4 CXCL8 ICAM1 IFNG IL10 IL17A
7
Show member pathways
13.37 CCL17 CD4 CXCL8 CXCR3 IL10 IL17A
8
Show member pathways
12.92 CXCL8 IFNG IL10 IL1B TNF
9
Show member pathways
12.9 CXCL8 ICAM1 IFNG IL1B IL33 IL4
10
Show member pathways
12.87 CD4 CXCL8 ICAM1 IFNG IL10 IL17A
11
Show member pathways
12.78 CXCL8 IFNG IL1B IL33 TNF
12
Show member pathways
12.72 CD4 IFNG IL10 IL17A IL1B IL4
13
Show member pathways
12.69 CD4 IFNG IL10 IL4 TNF
14
Show member pathways
12.69 CD4 IFNG IL10 IL17A IL1B TNF
15 12.65 IFNG IL10 IL17A IL1B IL4 TNF
16
Show member pathways
12.55 CD4 IFNG IL10 IL17A IL1B IL4
17
Show member pathways
12.52 ICAM1 IFNG IL4 TNF
18
Show member pathways
12.43 ICAM1 IFNG IL1B IL4 TNF
19
Show member pathways
12.41 CCL17 CXCL8 IFNG IL17A IL1B IL4
20
Show member pathways
12.35 IFNG IL10 IL1B IL4 TNF
21
Show member pathways
12.32 CXCL8 IFNG IL1B TNF
22 12.29 IFNG IL10 IL1B TNF
23
Show member pathways
12.29 CXCL8 IFNG IL1B IL4 TNF
24
Show member pathways
12.27 IFNG IL10 IL4 IL5
25 12.23 CXCL8 IL10 IL1B TNF
26 12.21 ICAM1 IFNG IL1B SELE TNF
27
Show member pathways
12.18 CXCL8 IFNG IL10 IL17A IL1B IL4
28 12.15 CXCL8 ICAM1 IFNG IL1B IL4 TNF
29 12.14 CD4 IFNG IL10 IL4 IL5 TNF
30 12.11 CXCL8 ICAM1 IL10 IL17A IL1B IL4
31
Show member pathways
12.09 CD4 IFNG IL10 IL17A IL1B TNF
32
Show member pathways
12.07 CD4 IFNG IL17A IL1B IL4
33
Show member pathways
12.06 CD4 IFNG IL1B IL4
34 12.05 CXCL8 ICAM1 IL1B SELE TNF
35 12.04 ICAM1 IL1B SELE TNF
36 12.04 CD4 IL1B IL4 IL5 TNF
37 12.03 CXCL8 IFNG IL10 IL1B TNF
38 12 CXCL8 ICAM1 IFNG IL17A IL1B TNF
39 11.98 CXCL8 ICAM1 IL1B TNF
40 11.95 CXCL8 IFNG IL1B
41 11.95 CXCL8 ICAM1 IFNG IL4 IL5 SELE
42
Show member pathways
11.91 CXCL8 IFNG IL4 IL5 TNF
43 11.9 CD4 IFNG IL10 IL1B TNF
44
Show member pathways
11.89 CXCL8 ICAM1 IL17A
45 11.87 CXCL8 IL10 IL1B TNF
46 11.86 ICAM1 IL10 IL4 IL5 TNF
47 11.85 CXCL8 IFNG IL1B
48
Show member pathways
11.82 CXCL8 ICAM1 IFNG IL1B SELE TNF
49 11.81 CXCL8 IL1B IL4 IL5 TNF
50 11.78 CCL17 IL10 IL4 IL5

GO Terms for Allergic Contact Dermatitis

Cellular components related to Allergic Contact Dermatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.9 CCL17 CXCL8 IFNG IL10 IL17A IL1B
2 membrane raft GO:0045121 9.56 CD4 ICAM1 SELE TNF
3 external side of plasma membrane GO:0009897 9.5 CD4 CXCR3 ICAM1 IFNG IL17A IL4
4 extracellular space GO:0005615 9.44 CCL17 CXCL8 ICAM1 IFNG IL10 IL17A

Biological processes related to Allergic Contact Dermatitis according to GeneCards Suite gene sharing:

(show top 50) (show all 56)
id Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 9.98 ICAM1 IL1B SELE TNF
2 response to lipopolysaccharide GO:0032496 9.97 ICAM1 IL10 IL1B SELE
3 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.97 CCL17 CD4 ICAM1 TNF
4 chemotaxis GO:0006935 9.95 CCL17 CXCL8 CXCR3 IL4
5 movement of cell or subcellular component GO:0006928 9.88 CXCL8 CXCR3 IFNG
6 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.88 CD4 ICAM1 IL4 IL5
7 positive regulation of protein phosphorylation GO:0001934 9.88 CD4 IFNG IL1B IL4 TNF
8 chemokine-mediated signaling pathway GO:0070098 9.87 CCL17 CXCL8 CXCR3
9 cellular response to interleukin-1 GO:0071347 9.87 CCL17 CXCL8 ICAM1 IL17A
10 regulation of insulin secretion GO:0050796 9.86 IFNG IL1B TNF
11 calcium-mediated signaling GO:0019722 9.84 CXCL8 CXCR3 SELE
12 neutrophil chemotaxis GO:0030593 9.84 CCL17 CXCL8 IFNG IL1B
13 positive regulation of interleukin-6 production GO:0032755 9.83 IL1B IL33 TNF
14 positive regulation of T cell proliferation GO:0042102 9.83 CD4 IFNG IL1B IL4
15 extrinsic apoptotic signaling pathway GO:0097191 9.8 IFNG IL33 TNF
16 cellular response to lipopolysaccharide GO:0071222 9.8 CXCL8 ICAM1 IFNG IL10 TNF
17 negative regulation of endothelial cell apoptotic process GO:2000352 9.78 ICAM1 IL10 IL4
18 positive regulation of osteoclast differentiation GO:0045672 9.77 IFNG IL17A TNF
19 defense response to protozoan GO:0042832 9.75 IFNG IL10 IL4
20 negative regulation of growth of symbiont in host GO:0044130 9.73 IFNG IL10 TNF
21 positive regulation of nitric oxide biosynthetic process GO:0045429 9.73 ICAM1 IFNG IL1B TNF
22 leukocyte tethering or rolling GO:0050901 9.72 SELE TNF
23 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.72 IL1B TNF
24 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.72 IFNG IL1B TNF
25 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.72 IL10 IL1B IL4 IL5 TNF
26 negative regulation of nitric oxide biosynthetic process GO:0045019 9.71 IL10 IL4
27 response to molecule of bacterial origin GO:0002237 9.71 CXCL8 IL10
28 positive regulation of macrophage activation GO:0043032 9.71 IL10 IL33
29 positive regulation of podosome assembly GO:0071803 9.71 IL5 TNF
30 positive regulation of interleukin-2 biosynthetic process GO:0045086 9.71 CD4 IL1B
31 positive regulation of immunoglobulin secretion GO:0051024 9.7 IL33 IL5
32 positive regulation of isotype switching to IgG isotypes GO:0048304 9.7 IFNG IL4
33 positive regulation of interleukin-6 biosynthetic process GO:0045410 9.69 IFNG IL1B
34 endothelial cell apoptotic process GO:0072577 9.69 IL10 TNF
35 positive regulation of interleukin-13 production GO:0032736 9.69 IL33 IL4
36 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.69 IL10 IL1B TNF
37 regulation of defense response to virus by host GO:0050691 9.68 IFNG IL1B
38 regulation of establishment of endothelial barrier GO:1903140 9.68 IL1B TNF
39 negative regulation of cytokine secretion involved in immune response GO:0002740 9.67 IL10 TNF
40 positive regulation of interleukin-23 production GO:0032747 9.66 IFNG IL17A
41 positive regulation of fever generation GO:0031622 9.65 IL1B TNF
42 sequestering of triglyceride GO:0030730 9.64 IL1B TNF
43 regulation of isotype switching GO:0045191 9.64 IL10 IL4
44 positive regulation of mononuclear cell migration GO:0071677 9.63 IL4 TNF
45 positive regulation of MHC class II biosynthetic process GO:0045348 9.63 IFNG IL10 IL4
46 receptor biosynthetic process GO:0032800 9.62 IL10 TNF
47 positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 9.61 ICAM1 TNF
48 inflammatory response GO:0006954 9.61 CCL17 CXCL8 CXCR3 IL10 IL17A IL1B
49 positive regulation of vitamin D biosynthetic process GO:0060557 9.6 IFNG TNF
50 type 2 immune response GO:0042092 9.54 IL10 IL33 IL4

Molecular functions related to Allergic Contact Dermatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.36 CCL17 CXCL8 IFNG IL10 IL17A IL1B

Sources for Allergic Contact Dermatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
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36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
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48 NDF-RT
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65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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