MCID: ALL014
MIFTS: 32

Allergic Encephalomyelitis malady

Rare diseases, Immune diseases categories

Aliases & Classifications for Allergic Encephalomyelitis

About this section

Aliases & Descriptions for Allergic Encephalomyelitis:

Name: Allergic Encephalomyelitis 45
 
Experimental Autoimmune Encephalomyelitis 65


Classifications:



Summaries for Allergic Encephalomyelitis

About this section
Wikipedia:68 The experimental autoimmune encephalomyelitis, sometimes experimental allergic encephalomyelitis (EAE)... more...

MalaCards based summary: Allergic Encephalomyelitis, also known as experimental autoimmune encephalomyelitis, is related to orchitis and endotheliitis. An important gene associated with Allergic Encephalomyelitis is MBP (Myelin Basic Protein), and among its related pathways are Glial Cell Differentiation and Mineral absorption. Affiliated tissues include t cells, brain and spinal cord, and related mouse phenotypes are behavior/neurological and nervous system.

Related Diseases for Allergic Encephalomyelitis

About this section

Graphical network of the top 20 diseases related to Allergic Encephalomyelitis:



Diseases related to allergic encephalomyelitis

Symptoms for Allergic Encephalomyelitis

About this section

Drugs & Therapeutics for Allergic Encephalomyelitis

About this section

Interventional clinical trials:

idNameStatusNCT IDPhase
1Evaluation of Autologous Mesenchymal Stem Cell Transplantation (Effects and Side Effects) in Multiple SclerosisCompletedNCT01377870Phase 1, Phase 2
2Mesenchymal Stem Cells for the Treatment of MSActive, not recruitingNCT00781872Phase 1, Phase 2
3A Study to Assess the Relative Bioavailability of Different Formulations of GSK2018682, a Sphingosine-1-phosphate Receptor Subtype 1 Agonist, in Healthy Volunteers.CompletedNCT01466322Phase 1
4A Pilot Study of Intermittent Calorie Restriction in Multiple SclerosisRecruitingNCT02647502Phase 1

Search NIH Clinical Center for Allergic Encephalomyelitis

Genetic Tests for Allergic Encephalomyelitis

About this section

Anatomical Context for Allergic Encephalomyelitis

About this section

MalaCards organs/tissues related to Allergic Encephalomyelitis:

33
T cells, Brain, Spinal cord, B cells, Bone, Pituitary, Monocytes

Animal Models for Allergic Encephalomyelitis or affiliated genes

About this section

MGI Mouse Phenotypes related to Allergic Encephalomyelitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.0HMOX1, MBP, MOG, PLP1, POMC
2MP:00036317.6FTH1, MBP, MOG, PLP1, POMC
3MP:00053767.5FTH1, HMOX1, MBP, PLP1, POMC
4MP:00053847.4FTH1, HMOX1, MBP, MOG, PLP1, POMC
5MP:00053977.1FTH1, HMOX1, MBP, MOG, PLP1, POMC
6MP:00053876.8FTH1, HMOX1, MBP, MOG, PLP1, POMC

Publications for Allergic Encephalomyelitis

About this section

Articles related to Allergic Encephalomyelitis:

(show top 50)    (show all 538)
idTitleAuthorsYear
1
Analysis of the direct injury effector of oligodendroglia cells or myelin sheath in an experimental allergic encephalomyelitis model induced by the MOG35-55 peptide. (26459920)
2015
2
Effect of oral administration of pig spinal cord hydrolysate on clinical and histopathological symptoms of experimental allergic encephalomyelitis in rats. (26216115)
2015
3
Prevention of clinical and histological signs of proteolipid protein (PLP)-induced experimental allergic encephalomyelitis (EAE) in mice by the water-soluble carbon monoxide-releasing molecule (CORM)-A1. (21235533)
2011
4
The kinase inhibitory region of SOCS-1 is sufficient to inhibit T-helper 17 and other immune functions in experimental allergic encephalomyelitis. (21131060)
2011
5
Augmentation of regulatory B cell activity in experimental allergic encephalomyelitis by glatiramer acetate. (21111489)
2011
6
Experimental study of implantation of neurotropin-3 modified olfactory ensheathing cells in experimental allergic encephalomyelitis]. (20017332)
2009
7
Gene-based delivery of IFN-beta is efficacious in a murine model of experimental allergic encephalomyelitis. (16800783)
2006
8
How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis. (16802293)
2006
9
Latent TGF-beta1-transduced CD4+ T cells suppress the progression of allergic encephalomyelitis. (16244108)
2006
10
Effects of pixantrone on immune-cell function in the course of acute rat experimental allergic encephalomyelitis. (16120465)
2005
11
Pixantrone (BBR2778) reduces the severity of experimental allergic encephalomyelitis. (15145604)
2004
12
Adult gonadal hormones selectively regulate sexually dimorphic quantitative traits observed in experimental allergic encephalomyelitis. (14695330)
2004
13
Mast cells exert effects outside the central nervous system to influence experimental allergic encephalomyelitis disease course. (14530364)
2003
14
A human leucocyte antigen-DR1 transgene confers susceptibility to experimental allergic encephalomyelitis elicited by an epitope of myelin basic protein. (12869140)
2003
15
Expression and activity of nitric oxide synthase isoforms in rat brain during the development of experimental allergic encephalomyelitis. (11869804)
2002
16
Quantification and localization of PEGylated polycyanoacrylate nanoparticles in brain and spinal cord during experimental allergic encephalomyelitis in the rat. (11994126)
2002
17
Cuprizone and piperonyl butoxide, proposed inhibitors of T-cell function, attenuate experimental allergic encephalomyelitis in SJL mice. (11585623)
2001
18
Essential role of TGF-beta in the natural resistance to experimental allergic encephalomyelitis in rats. (11298338)
2001
19
Mycophenolate mofetil treatment accelerates recovery from experimental allergic encephalomyelitis. (11562063)
2001
20
Bone marrow-derived dendritic cells from experimental allergic encephalomyelitis induce immune tolerance to EAE in Lewis rats. (11529923)
2001
21
Reversal of experimental allergic encephalomyelitis with non-mitogenic, non-depleting anti-CD3 mAb therapy with a preferential effect on T(h)1 cells that is augmented by IL-4. (11526091)
2001
22
Astrocyte-targeted expression of IL-12 induces active cellular immune responses in the central nervous system and modulates experimental allergic encephalomyelitis. (10779748)
2000
23
Treatment of experimental allergic encephalomyelitis (EAE) induced by guinea pig myelin basic protein epitope 72-85 with a human MBP(87-99) analogue and effects of cyclic peptides. (11003134)
2000
24
Experimental allergic encephalomyelitis animal models for analyzing features of multiple sclerosis. (10729911)
2000
25
Activation of nuclear factor-kB in the spinal cord of experimental allergic encephalomyelitis. (10841980)
2000
26
Inhibition of experimental allergic encephalomyelitis with an antibody that recognizes a novel antigen expressed on lymphocytes, endothelial cells, and microglia. (10744067)
2000
27
A gene therapy or purified CTLA4IgG treatment of experimental allergic encephalomyelitis. (10642893)
1999
28
Galectin-3/MAC-2 in experimental allergic encephalomyelitis. (10619568)
1999
29
Genetic analysis of disease subtypes and sexual dimorphisms in mouse experimental allergic encephalomyelitis (EAE): relapsing/remitting and monophasic remitting/nonrelapsing EAE are immunogenetically distinct. (10072563)
1999
30
Correlation between MRI and clinico-pathological manifestations in Lewis rats protected from experimental allergic encephalomyelitis by acylated synthetic peptide of myelin basic protein. (10372527)
1999
31
Dendritic cells in experimental allergic encephalomyelitis and multiple sclerosis. (10695720)
1999
32
Type IV phosphodiesterase inhibition in experimental allergic encephalomyelitis of Lewis rats: sequential gene expression analysis of cytokines, adhesion molecules and the inducible nitric oxide synthase. (10385042)
1999
33
Microvascular and cellular responses in the retina of rats with acute experimental allergic encephalomyelitis (EAE). (9669699)
1998
34
B-cell-deficient mice develop experimental allergic encephalomyelitis with demyelination after myelin oligodendrocyte glycoprotein sensitization. (9794370)
1998
35
Abnormalities of cardiac repolarization in multiple sclerosis: relationship with a model of allergic encephalomyelitis in rat. (9626255)
1998
36
The pattern of cytokine gene expression in lymphoid organs and peripheral blood mononuclear cells of mice with experimental allergic encephalomyelitis. (9670856)
1998
37
Essential fatty acid preparation improves biochemical and cognitive functions in experimental allergic encephalomyelitis rats. (9203563)
1997
38
Inhibition of allergic encephalomyelitis in marmosets by vaccination with recombinant vaccinia virus encoding for myelin basic protein. (9394784)
1997
39
Perfluoro-15-crown-5-ether labelled macrophages in adoptive transfer experimental allergic encephalomyelitis. (9167839)
1997
40
Suppression of acute experimental allergic encephalomyelitis in Lewis rats with a mycophenolic acid derivative. (9362104)
1997
41
Modulation of Outward K(+) Conductance Is a Post-Activational Event in Rat T Lymphocytes Responsible for the Adoptive Transfer of Experimental Allergic Encephalomyelitis. (11725140)
1997
42
Native, but not genetically inactivated, pertussis toxin protects mice against experimental allergic encephalomyelitis. (8640862)
1996
43
Analysis of T cell receptor beta chains in the rat: I. Allelic polymorphism of V beta 8.2 is not a predisposing genetic factor in susceptibility to experimental allergic encephalomyelitis. (8892081)
1996
44
A CD4-CDR3 peptide analog inhibits both primary and secondary autoreactive CD4+ T cell responses in experimental allergic encephalomyelitis. (8871674)
1996
45
Experimental allergic encephalomyelitis in non-human primates: MRI and MRS may predict the type of brain damage. (7547186)
1995
46
Eicosenoids Modify Experimental Allergic Encephalomyelitis. (11854849)
1995
47
Staphylococcal enterotoxin B and tumor-necrosis factor-alpha-induced relapses of experimental allergic encephalomyelitis: protection by transforming growth factor-beta and interleukin-10. (7489740)
1995
48
The IFN pregnancy recognition hormone IFN-tau blocks both development and superantigen reactivation of experimental allergic encephalomyelitis without associated toxicity. (7544384)
1995
49
Experimental allergic encephalomyelitis, beta-adrenergic receptors and interferon gamma-secreting cells in beta-adrenergic agonist-treated rats. (8788119)
1995
50
Soluble recombinant complement receptor 1 inhibits inflammation and demyelination in antibody-mediated demyelinating experimental allergic encephalomyelitis. (8189065)
1994

Variations for Allergic Encephalomyelitis

About this section

Expression for genes affiliated with Allergic Encephalomyelitis

About this section
Search GEO for disease gene expression data for Allergic Encephalomyelitis.

Pathways for genes affiliated with Allergic Encephalomyelitis

About this section

Pathways related to Allergic Encephalomyelitis according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.6MBP, PLP1
29.1FTH1, HMOX1

GO Terms for genes affiliated with Allergic Encephalomyelitis

About this section

Cellular components related to Allergic Encephalomyelitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1myelin sheathGO:00432099.1MBP, MOG, PLP1

Biological processes related to Allergic Encephalomyelitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1axon ensheathmentGO:000836610.1MBP, PLP1
2myelinationGO:00425529.8MBP, PLP1
3substantia nigra developmentGO:00217629.8MBP, PLP1
4central nervous system developmentGO:00074179.5MBP, MOG
5regulation of blood pressureGO:00082179.3HMOX1, POMC
6cellular iron ion homeostasisGO:00068799.0FTH1, HMOX1

Molecular functions related to Allergic Encephalomyelitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of myelin sheathGO:00199119.6MBP, PLP1

Sources for Allergic Encephalomyelitis

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet