MCID: ALP056
MIFTS: 13

Alpha-Mannosidosis, Adult Form

Categories: Neuronal diseases, Bone diseases, Metabolic diseases, Rare diseases, Genetic diseases, Eye diseases

Aliases & Classifications for Alpha-Mannosidosis, Adult Form

MalaCards integrated aliases for Alpha-Mannosidosis, Adult Form:

Name: Alpha-Mannosidosis, Adult Form 56
Lysosomal Alpha-D-Mannosidase Deficiency, Adult Form 56

Classifications:



External Ids:

Orphanet 56 ORPHA309288
ICD10 via Orphanet 34 E77.1

Summaries for Alpha-Mannosidosis, Adult Form

MalaCards based summary : Alpha-Mannosidosis, Adult Form, is also known as lysosomal alpha-d-mannosidase deficiency, adult form. An important gene associated with Alpha-Mannosidosis, Adult Form is MAN2B1 (Mannosidase Alpha Class 2B Member 1). The drugs Cyclophosphamide and Busulfan have been mentioned in the context of this disorder. Affiliated tissues include bone and bone marrow.

Related Diseases for Alpha-Mannosidosis, Adult Form

Symptoms & Phenotypes for Alpha-Mannosidosis, Adult Form

Drugs & Therapeutics for Alpha-Mannosidosis, Adult Form

Drugs for Alpha-Mannosidosis, Adult Form (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cyclophosphamide Approved, Investigational Phase 2 50-18-0, 6055-19-2 2907
2
Busulfan Approved, Investigational Phase 2 55-98-1 2478
3
Prednisolone Approved, Vet_approved Phase 2 50-24-8 5755
4
Methylprednisolone Approved, Vet_approved Phase 2 83-43-2 6741
5
Mycophenolic acid Approved Phase 2 24280-93-1 446541
6
Mycophenolate mofetil Approved, Investigational Phase 2 128794-94-5 5281078
7
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
8
Mesna Approved Phase 2 3375-50-6 598
9
alemtuzumab Approved, Investigational Phase 2 216503-57-0
10
Benzocaine Approved Phase 2 1994-09-7, 94-09-7 2337
11 tannic acid Approved, Nutraceutical Phase 2
12 Prednisolone acetate Phase 2
13 Alkylating Agents Phase 2
14 Methylprednisolone acetate Phase 2
15 Methylprednisolone Hemisuccinate Phase 2
16 Immunosuppressive Agents Phase 2
17 Prednisolone hemisuccinate Phase 2
18 Prednisolone phosphate Phase 2
19 Antilymphocyte Serum Phase 2
20 Antirheumatic Agents Phase 2
21 Cyclosporins Phase 2
22 Dermatologic Agents Phase 2
23 Anti-Bacterial Agents Phase 2
24 Anti-Infective Agents Phase 2
25 Antifungal Agents Phase 2
26 Antibiotics, Antitubercular Phase 2
27 Calcineurin Inhibitors Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Stem Cell Transplantation for Hurler Completed NCT00176917 Phase 2 Busulfan, Cyclophosphamide, ATG
2 Allogeneic Bone Marrow Transplant for Inherited Metabolic Disorders Active, not recruiting NCT01043640 Phase 2 Campath-1H;Cyclophosphamide;Busulfan;Cyclosporine A;Mycophenolate Mofetil

Search NIH Clinical Center for Alpha-Mannosidosis, Adult Form

Genetic Tests for Alpha-Mannosidosis, Adult Form

Anatomical Context for Alpha-Mannosidosis, Adult Form

MalaCards organs/tissues related to Alpha-Mannosidosis, Adult Form:

39
Bone, Bone Marrow

Publications for Alpha-Mannosidosis, Adult Form

Variations for Alpha-Mannosidosis, Adult Form

Expression for Alpha-Mannosidosis, Adult Form

Search GEO for disease gene expression data for Alpha-Mannosidosis, Adult Form.

Pathways for Alpha-Mannosidosis, Adult Form

GO Terms for Alpha-Mannosidosis, Adult Form

Sources for Alpha-Mannosidosis, Adult Form

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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