MCID: ALV002
MIFTS: 57

Alveolar Echinococcosis malady

Infectious diseases category

Summaries for Alveolar Echinococcosis

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 An echinococcosis that is caused by the larvae of echinococcus multilocularis affecting the liver as a slow growing, destructive tumor, with abdominal pain, biliary obstruction, and occasionally metastatic lesions into the lungs and brain.

MalaCards: Alveolar Echinococcosis, also known as multilocular hydatid, is related to echinococcosis and hepatitis. An important gene associated with Alveolar Echinococcosis is MT-CO1 (mitochondrially encoded cytochrome c oxidase I), and among its related pathways are Malaria and Cytokines and Inflammatory Response. The compounds tacrolimus and solium have been mentioned in the context of this disorder. Affiliated tissues include liver, brain and lung, and related mouse phenotypes are nervous system and muscle.

Wikipedia:63 Alveolar hydatid disease (AHD), also known as alveolar echinococcosis, alveolar colloid of the liver,... more...

Aliases & Classifications for Alveolar Echinococcosis

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 48Orphanet, 60UMLS, 56SNOMED-CT, 27ICD9CM, 26ICD10 via Orphanet, 61UMLS via Orphanet, 35MESH via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Characteristics (Orphanet epidemiological data):

48
alveolar echinococcosis:
Age of onset: Variable


Aliases & Descriptions:

alveolar echinococcosis 8 42 48 60
multilocular hydatid 8
small fox tapeworm 8
alveolococcosis 8
echinococcosis 42


External Ids:

Disease Ontology8 DOID:12148
ICD9CM27 122.7
ICD10 via Orphanet26 B67.6, B67.7, B67.5
SNOMED-CT56 21009004, 240816000
UMLS via Orphanet61 C0948954
MESH via Orphanet35 C536591

Related Diseases for Alveolar Echinococcosis

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Alveolar Echinococcosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 167)
idRelated DiseaseScoreTop Affiliating Genes
1echinococcosis32.1MT-CO1
2hepatitis31.3HLA-DRB1, HLA-A, TAP2
3acquired immunodeficiency syndrome30.1HLA-B
4pancreatitis30.1IL10
5hepatocellular carcinoma30.1KLRK1, HLA-DRB1, HLA-A, TAP1, TAP2
6arthritis30.1IFNG, TNF, HLA-C, HLA-B, HLA-DRB1, HLA-A
7rheumatoid arthritis30.1KLRK1, IFNG, TNF, TSPAN32, TAP2, IL10
8thyroiditis29.8HLA-C, HLA-DRB1
9pneumonia29.8TNF, IL10
10breast cancer29.8HLA-B, HLA-A, TAP1, TAP2, TSPAN32
11tuberculosis29.8IL10, KLRK1, IFNG, TNF, HLA-DQB1, HLA-DRB1
12cystic echinococcosis10.8
13cerebritis10.6
14hepatitis a10.6
15polycystic echinococcosis10.5
16cysticercosis10.5
17liver disease10.5
18taeniasis10.4
19prostatic cyst10.1
20mediastinitis10.1
21peritonitis10.1
22prostatitis10.1
23pulmonary embolism10.1
24ovarian cyst10.0
25bronchiectasis10.0TAP2
26acute leukemia10.0CD8A
27aphthous stomatitis10.0HLA-B
28polymyositis10.0HLA-B
29dermatomyositis10.0HLA-B
30myositis10.0HLA-B
31myopathy10.0HLA-B
32viral hepatitis10.0HLA-DRB1
33encephalitis10.0HLA-B
34herpes simplex10.0HLA-B
35vogt-koyanagi-harada disease10.0HLA-DRB1
36pemphigus vulgaris10.0HLA-DRB1
37leprosy10.0HLA-DRB1
38measles10.0HLA-A
39amyloidosis10.0HLA-B
40pemphigus foliaceus10.0HLA-DRB1
41liver cirrhosis10.0HLA-DRB1
42endometriosis10.0HLA-A
43cervical intraepithelial neoplasia10.0HLA-A
44common variable immune deficiency10.0IL10
45sjogren's syndrome10.0TAP1, TAP2
46disseminated intravascular coagulation10.0TSPAN32
47polymyalgia rheumatica10.0HLA-DRB1
48pulmonary fibrosis10.0CD36
49paracoccidioidomycosis10.0IL10
50cholestasis10.0HLA-B

Graphical network of the top 20 diseases related to Alveolar Echinococcosis:



Diseases related to alveolar echinococcosis

Clinical Features for Alveolar Echinococcosis

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Drugs & Therapeutics for Alveolar Echinococcosis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Alveolar Echinococcosis

Drug clinical trials:

Search ClinicalTrials for Alveolar Echinococcosis

Search NIH Clinical Center for Alveolar Echinococcosis

Search CenterWatch for Alveolar Echinococcosis

Genetic Tests for Alveolar Echinococcosis

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Anatomical Context for Alveolar Echinococcosis

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32MalaCards
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MalaCards organs/tissues related to Alveolar Echinococcosis:

32
Liver, Brain, Lung, Testes, Skin, Bone, Pancreas, Adrenal gland, T cells, Testis, Breast, Spleen, Spinal cord, Prostate

Animal Models for Alveolar Echinococcosis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Alveolar Echinococcosis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036319.1HLA-DQB1, CD8A, TAP1, SLC4A3
2MP:00053698.8HLA-DQB1, MT-CO1, CD36, SLC4A3
3MP:00107686.5IFNG, TNF, HLA-DQB1, HLA-B, CD8A, CD36
4MP:00053976.0HLA-DQB1, TNF, IFNG, KLRK1, HLA-B, CD8A
5MP:00053875.8TSPAN32, KLRK1, IFNG, TNF, HLA-DQB1, HLA-B
6MP:00053845.8HLA-B, HLA-DQB1, TNF, IFNG, KLRK1, MT-CO1

Publications for Alveolar Echinococcosis

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50PubMed
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Articles related to Alveolar Echinococcosis:

(show top 50)    (show all 358)
idTitleAuthorsYear
1
Diagnostics and epidemiology of alveolar echinococcosis in slaughtered pigs from large-scale husbandries in Germany. (23093207)
2013
2
Detecting nested clusters of human alveolar echinococcosis. (23962413)
2013
3
Alveolar echinococcosis-spreading disease challenging clinicians: a case report and literature review. (23864792)
2013
4
Surgical treatment for hepatic alveolar echinococcosis: report of 50 cases. (22469722)
2012
5
Time course of the antibody response in humans compared with rats experimentally infected with hepatic alveolar echinococcosis. (23137748)
2012
6
Immunochromatographic test with recombinant Em18 antigen for the follow-up study of alveolar echinococcosis. (21715578)
2011
7
Specific IgG responses to recombinant antigen B and em18 in cystic and alveolar echinococcosis in china. (20042519)
2010
8
Primary alveolar echinococcosis: course of larval development and antibody responses in intermediate host rodents with different genetic backgrounds after oral infection with eggs of Echinococcus multilocularis. (20601109)
2010
9
Limitations of amphotericin B and nitazoxanide in the treatment of alveolar echinococcosis. (19208302)
2009
10
Alveolar and cystic echinococcosis: towards novel chemotherapeutical treatment options. (19296876)
2009
11
Alveolar echinococcosis localized in the liver, lung and brain. (18208675)
2008
12
Brain and lung metastasis of alveolar echinococcosis in a refugee from a hyperendemic area. (18927422)
2008
13
Socioeconomic and behavior risk factors of human alveolar echinococcosis in Tibetan communities in Sichuan, People's Republic of China. (16687693)
2006
14
Serodiagnostic potential of chemically synthesized glycosphingolipid antigens in an enzyme-linked immunosorbent assay for alveolar echinococcosis. (17125548)
2006
15
Community surveys and risk factor analysis of human alveolar and cystic echinococcosis in Ningxia Hui Autonomous Region, China. (17128341)
2006
16
Orthotopic liver transplantation for incurable alveolar echinococcosis: report of five cases from west China. (15964373)
2005
17
Comparison of contrast-enhanced power Doppler ultrasound (Levovist) and computed tomography in alveolar echinococcosis. (15965776)
2005
18
Epidemiology of alveolar echinococcosis in southern Cantal, Auvergne region, France. (15469627)
2004
19
Use of two sensitive and specific immunoblot markers, em70 and em90, for diagnosis of alveolar echinococcosis. (15243114)
2004
20
Structured treatment interruption in patients with alveolar echinococcosis. (14768005)
2004
21
Hepatic alveolar echinococcosis in cynomolgus monkeys (Macaca fascicularis). (15133171)
2004
22
Alveolar echinococcosis of the liver in an adult with human immunodeficiency virus type-1 infection. (15624896)
2004
23
Mediastinal recurrence of alveolar echinococcosis after liver transplantation. (12514779)
2003
24
Experience of liver transplantation for incurable alveolar echinococcosis: a 45-case European collaborative report. (12660515)
2003
25
Hepatic alveolar echinococcosis: clinical report from an endemic region. (12500915)
2002
26
Veterinary aspects of alveolar echinococcosis--a zoonosis of public health significance. (11516580)
2001
27
Differential serodiagnosis of cystic and alveolar echinococcosis using native and recombinant antigens in Japan. (12041571)
2001
28
HASTE MRCP and MRI findings in alveolar echinococcosis of the liver. (11903184)
2001
29
Extrahepatic alveolar echinococcosis without liver involvement: a rare manifestation. (10879649)
2000
30
An epidemiological and ecological study of human alveolar echinococcosis transmission in south Gansu, China. (11080507)
2000
31
Experimental investigations on the B and T cell immune response in primary alveolar echinococcosis. (10417675)
1999
32
Surgery and outcome of alveolar echinococcosis of the liver: historical comparison of mass screening systems in Japan. (9331854)
1997
33
Epidemiology of alveolar echinococcosis in southern Germany (Bavaria). (7622269)
1995
34
Interleukin-5 is the predominant cytokine produced by peripheral blood mononuclear cells in alveolar echinococcosis. (7729873)
1995
35
MR imaging in alveolar echinococcosis of bone. (8539445)
1995
36
Cellular localisations of interleukin-1 beta, interleukin-6 and tumor necrosis factor-alpha mRNA in a parasitic granulomatous disease of the liver, alveolar echinococcosis. (7880977)
1994
37
Intracranial alveolar echinococcosis: CT and MRI. (8065572)
1994
38
Serological differentiation between cystic and alveolar echinococcosis by use of recombinant larval antigens. (8308113)
1993
39
Colloid liver SPECT of hepatic alveolar echinococcosis. (8292456)
1993
40
CT in lobar atrophy of the liver caused by alveolar echinococcosis. (1545016)
1992
41
Alveolar echinococcosis of the liver: MR findings. (2370360)
1990
42
Alveolar echinococcosis with involvement of the ureter and testis. (2388340)
1990
43
Alveolar echinococcosis of the liver. (2567298)
1989
44
Autoantibodies in humans with cystic or alveolar echinococcosis. (3496692)
1986
45
Pulmonary embolism from a parasitic cardiac clot secondary to hepatic alveolar echinococcosis. (3782269)
1986
46
Collagen immunotyping of the hepatic fibrosis in human alveolar echinococcosis. (3515794)
1986
47
Hepatic alveolar echinococcosis invading pancreas, vertebrae, and spinal cord. (7129411)
1982
48
Alveolar echinococcosis of the liver; studies on 60 operated cases. (6153887)
1980
49
Alveolar Echinococcosis. (20326813)
1961
50
Alveolar echinococcosis; 6 new case reports]. (13602375)
1958

Genetic Variations for Alveolar Echinococcosis

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Expression for genes affiliated with Alveolar Echinococcosis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Alveolar Echinococcosis

Search GEO for disease gene expression data for Alveolar Echinococcosis.

Pathways for genes affiliated with Alveolar Echinococcosis

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Sources:
29KEGG, 37NCBI BioSystems Database, 53Reactome, 12EMD Millipore, 51QIAGEN, 4Cell Signaling Technology, 52R&D Systems, 55SinoBiological
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Pathways related to Alveolar Echinococcosis according to GeneCards/GeneDecks:

(show all 50)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.3KLRK1
210.1HLA-DRB1
310.0CD8A, TAP1
4
Hide members
9.5HLA-DRB1, HLA-DRB5, HLA-DQB1
5
Hide members
9.5HLA-DRB1, HLA-DRB5, HLA-DQB1
6
Immune response Antigen presentation by MHC class II
Hide members
9.5HLA-DRB1, HLA-DRB5, HLA-DQB1
79.5HLA-DRB1, HLA-DRB5, HLA-DQB1
8
Hide members
9.5HLA-DRB1, HLA-DRB5, HLA-DQB1
9
Immune response NFAT in immune response
Hide members
9.5HLA-DRB1, HLA-DRB5, HLA-DQB1
109.5HLA-DRB1, HLA-DRB5, HLA-DQB1
11
Immune response ICOS pathway in T-helper cell
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9.5HLA-DRB1, HLA-DRB5, HLA-DQB1
129.5HLA-DQB1, HLA-DRB5, HLA-DRB1
139.5HLA-DQB1, HLA-DRB5, HLA-DRB1
14
Hide members
9.5HLA-DRB1, HLA-A, CD8A
159.5IFNG, IL10
169.4TAP1, HLA-B, IFNG
17
Immune response IFN alpha/beta signaling pathway
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9.4HLA-C, HLA-B, HLA-A
189.4HLA-C, HLA-B, HLA-A
19
Hide members
9.3HLA-DQB1, HLA-DRB5, HLA-DRB1, CD8A
20
Hide members
9.3HLA-DQB1, HLA-DRB5, HLA-DRB1, CD8A
219.3CD8A, IL10, TAP1, TAP2
22
Hide members
9.2KLRK1, HLA-C, HLA-B, HLA-A
239.2HLA-C, HLA-DQB1, HLA-B, HLA-DRB5
249.1HLA-DQB1, HLA-DRB5, HLA-DRB1, IL10
259.0CD36, TNF
26
Hide members
9.0CD8A, HLA-A, HLA-DRB1, IFNG
27
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8.9HLA-C, HLA-B, HLA-A, TAP1, TAP2
28
Hide members
8.9IL10, TNF, IFNG
298.9IL10, TNF, IFNG
30
Hide members
8.9IL10, TNF, IFNG
318.9IFNG, TNF, IL10
328.7CD8A, HLA-A, TNF, IFNG
338.6HLA-C, HLA-B, HLA-A, CD8A, TAP1, TAP2
34
Hide members
8.6IFNG, TNF, CD8A, IL10
35
Hide members
8.5HLA-A, HLA-DRB5, HLA-DQB1, HLA-C, TNF
368.4TNF, HLA-DQB1, HLA-DRB5, HLA-DRB1, IL10
37
Hide members
8.4HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB1, HLA-A
38
Hide members
8.4HLA-DRB1, HLA-DRB5, HLA-DQB1, TNF, IFNG
398.2HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB1, HLA-A
408.1TNF, HLA-DRB5, HLA-DRB1, CD8A, CD36
41
Hide members
8.1HLA-C, HLA-B, HLA-A, CD36, TAP1, TAP2
42
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8.0KLRK1, IFNG, TNF, HLA-C, HLA-B, HLA-A
43
Hide members
7.9IFNG, TNF, HLA-DQB1, HLA-DRB5, HLA-DRB1, IL10
44
Hide members
7.9IFNG, HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB1
457.5IFNG, HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB1
467.1HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB1, HLA-A
47
Hide members
6.9IFNG, TNF, HLA-C, HLA-B, HLA-A, CD36
48
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6.8IFNG, TNF, HLA-C, HLA-DQB1, HLA-B, HLA-DRB5
49
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6.6IL10, IFNG, TNF, HLA-C, HLA-DQB1, HLA-B
50
Hide members
6.1HLA-B, HLA-DQB1, HLA-C, IFNG, KLRK1, HLA-DRB5

Compounds for genes affiliated with Alveolar Echinococcosis

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Sources:
44Novoseek, 49PharmGKB, 11DrugBank, 28IUPHAR, 59Tocris Bioscience, 24HMDB
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Compounds related to Alveolar Echinococcosis according to GeneCards/GeneDecks:

(show all 46)
idCompoundScoreTop Affiliating Genes
1tacrolimus44 49 1112.4IFNG
2solium4410.3MT-CO1, HLA-B
3dr-104410.2HLA-A, HLA-DRB1
4betaseron449.8IFNG, IL10
5cdp571449.7TNF, IL10
6abacavir44 49 1111.7HLA-B, TNF
7alpha-galactosylceramide449.7IL10, IFNG
8cyclosporin a44 28 5911.7IFNG, HLA-B, HLA-A
9glatiramer acetate44 1110.6IFNG, HLA-DRB1, IL10
10ribavirin44 49 1111.5IL10, HLA-B, IFNG
11ifn-alpha449.5TAP1, IL10, IFNG
12lipoteichoic acid449.5IL10, HLA-B, TNF
13taurine chloramine449.4IFNG, TNF
14gold sodium thiomalate449.4IFNG, TNF, HLA-DRB1
15blys449.4TNF, IL10
16vesnarinone449.4IFNG, TNF
17mip 1alpha449.4IL10, TNF
18allergens449.4IL10, HLA-DRB1, IFNG
19interferon gamma449.3IL10, TNF, IFNG
20gabexate mesilate449.3TNF, IL10
21natalizumab44 1110.3IFNG, TNF, IL10
22adalimumab44 49 1111.3IL10, TNF, IFNG
23il-12449.3IL10, TNF, IFNG
24rantes449.3HLA-B, TNF, IFNG
25imiquimod44 28 59 1112.3IFNG, TNF, IL10
26polymyxin b449.3IL10, TNF, IFNG
27okt3449.3IFNG, TNF, IL10
28gm-csf44 2810.3IL10, TNF, IFNG
29etanercept44 49 1111.2IL10, TNF, IFNG
30infliximab44 49 1111.2IL10, TNF, IFNG
31tarc449.2IFNG, TNF, IL10
32ivig449.2IL10, TNF, IFNG
33ccl344 2810.2IFNG, TNF, IL10
34neopterin449.1IFNG, TNF, IL10
35toxin-1449.1IL10, TNF
36il 10449.1IFNG, TNF, CD8A, IL10
37mycophenolate mofetil44 49 1111.0IL10, CD36, IFNG
38carbamazepine44 49 1111.0CD36, HLA-B, TNF
392,5-oligoadenylate449.0IFNG, TNF, HLA-B, IL10
40oligonucleotide449.0HLA-DQB1, HLA-B, HLA-DRB1, HLA-A, TAP1, TAP2
41budesonide44 49 1110.9IFNG, TNF, CD36
42polyinosinic-polycytidylic acid448.8IL10, HLA-B, TNF, IFNG, KLRK1
4315-deoxy-delta-12,14-prostaglandin j2448.5IL10, CD36, TNF, IFNG
44thalidomide44 49 59 1111.5IL10, CD36, TNF, IFNG
45calcitriol44 59 11 2411.4IFNG, TNF, CD36, IL10
46sb 20358044 599.3IFNG, TNF, CD36, IL10

GO Terms for genes affiliated with Alveolar Echinococcosis

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16Gene Ontology
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Cellular components related to Alveolar Echinococcosis according to GeneCards/GeneDecks:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1TAP complexGO:0428259.9TAP2, TAP1
2MHC class II protein complexGO:0426139.7HLA-DQB1, HLA-DRB5, HLA-DRB1
3clathrin-coated endocytic vesicle membraneGO:0306699.6HLA-DQB1, HLA-DRB5, HLA-DRB1
4MHC class I protein complexGO:0426129.6HLA-C, HLA-B, HLA-A
5transport vesicle membraneGO:0306589.6HLA-DRB1, HLA-DRB5, HLA-DQB1
6trans-Golgi network membraneGO:0325889.5HLA-DQB1, HLA-DRB5, HLA-DRB1
7early endosome membraneGO:0319019.4HLA-A, HLA-B, HLA-C
8phagocytic vesicle membraneGO:0306709.1HLA-A, HLA-B, HLA-C
9endocytic vesicle membraneGO:0306668.9CD36, HLA-DRB1, HLA-DRB5, HLA-DQB1
10integral to lumenal side of endoplasmic reticulum membraneGO:0715568.7HLA-A, HLA-DRB1, HLA-DRB5, HLA-B, HLA-DQB1, HLA-C
11ER to Golgi transport vesicle membraneGO:0125078.7HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB1, HLA-A
12Golgi membraneGO:0001398.6HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB1, HLA-A
13external side of plasma membraneGO:0098977.9IFNG, TNF, HLA-DRB5, HLA-DRB1, CD8A, CD36
14integral to plasma membraneGO:0058877.3TNF, HLA-C, HLA-B, HLA-DRB1, HLA-A, CD8A
15plasma membraneGO:0058866.3TNF, HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB1

Biological processes related to Alveolar Echinococcosis according to GeneCards/GeneDecks:

(show all 39)
idNameGO IDScoreTop Affiliating Genes
1cytosol to ER transportGO:04696710.3TAP2, TAP1
2intracellular transport of viral proteins in host cellGO:01906010.3TAP1, TAP2
3peptide transportGO:01583310.3TAP2, TAP1
4antigen processing and presentation of endogenous peptide antigen via MHC class IGO:01988510.2TAP2, TAP1
5regulation of interleukin-4 productionGO:03267310.2HLA-DRB1, HLA-DRB5
6regulation of interleukin-10 secretionGO:200117910.2HLA-DRB1, HLA-DRB5
7T-helper 1 type immune responseGO:04208810.0HLA-DRB1, HLA-DRB5
8immunoglobulin production involved in immunoglobulin mediated immune responseGO:0023819.9HLA-DRB1, HLA-DRB5, HLA-DQB1
9humoral immune response mediated by circulating immunoglobulinGO:0024559.9HLA-DQB1, HLA-DRB5, HLA-DRB1
10inflammatory response to antigenic stimulusGO:0024379.8HLA-DRB5, HLA-DRB1
11negative regulation of myeloid dendritic cell activationGO:0308869.8IL10, TSPAN32
12antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independentGO:0024809.8HLA-A, HLA-B, HLA-C
13negative regulation of interferon-gamma productionGO:0326899.8IL10, HLA-DRB1, HLA-DRB5
14negative regulation of T cell proliferationGO:0421309.8HLA-DRB5, HLA-DRB1, IL10
15positive regulation of MHC class II biosynthetic processGO:0453489.8IL10, IFNG
16positive regulation of insulin secretion involved in cellular response to glucose stimulusGO:0357749.7HLA-DRB1, HLA-DRB5
17T cell costimulationGO:0312959.7HLA-DQB1, HLA-DRB5, HLA-DRB1
18receptor biosynthetic processGO:0328009.7TNF, IL10
19T cell receptor signaling pathwayGO:0508529.7HLA-DQB1, HLA-DRB5, HLA-DRB1
20negative regulation of cytokine secretion involved in immune responseGO:0027409.7TNF, IL10
21positive regulation of vitamin D biosynthetic processGO:0605579.7TNF, IFNG
22positive regulation of calcidiol 1-monooxygenase activityGO:0605599.7IFNG, TNF
23antigen processing and presentation of exogenous peptide antigen via MHC class IIGO:0198869.7HLA-DRB1, HLA-DRB5, HLA-DQB1
24type I interferon-mediated signaling pathwayGO:0603379.7HLA-C, HLA-B, HLA-A
25detection of bacteriumGO:0160459.6HLA-B, HLA-DRB5, HLA-DRB1, HLA-A
26positive regulation of chemokine biosynthetic processGO:0450809.5TNF, IFNG
27regulation of immune responseGO:0507769.5HLA-C, HLA-B, HLA-A, CD8A
28positive regulation of membrane protein ectodomain proteolysisGO:0510449.4TNF, IFNG
29positive regulation of osteoclast differentiationGO:0456729.3TNF, IFNG
30positive regulation of T cell mediated cytotoxicityGO:0019169.3HLA-C, HLA-B, HLA-A, TAP1, TAP2
31defense response to protozoanGO:0428329.1TSPAN32, IFNG
32cellular response to lipopolysaccharideGO:0712228.9IFNG, CD36, IL10
33immune responseGO:0069558.6HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB1, HLA-A
34antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentGO:0024798.5HLA-C, HLA-B, HLA-A, CD36, TAP1, TAP2
35antigen processing and presentation of exogenous peptide antigen via MHC class IGO:0425908.5HLA-C, HLA-B, HLA-A, CD36, TAP1, TAP2
36antigen processing and presentation of peptide antigen via MHC class IGO:0024748.5HLA-C, HLA-B, HLA-A, CD36, TAP1, TAP2
37negative regulation of growth of symbiont in hostGO:0441308.5IFNG, TNF, CD36, IL10
38interferon-gamma-mediated signaling pathwayGO:0603338.3HLA-A, HLA-DRB1, HLA-DRB5, HLA-B, HLA-DQB1, HLA-C
39cytokine-mediated signaling pathwayGO:0192218.3IFNG, HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB1

Molecular functions related to Alveolar Echinococcosis according to GeneCards/GeneDecks:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1tapasin bindingGO:04698010.1TAP1, TAP2
2peptide transporter activityGO:01519710.0TAP1, TAP2
3TAP2 bindingGO:04697910.0TAP1, TAP2
4TAP1 bindingGO:0469789.9TAP1, TAP2
5MHC class I protein bindingGO:0422889.9TAP2, TAP1, CD8A
6MHC class II receptor activityGO:0323959.8HLA-DRB1, HLA-DQB1
7oligopeptide-transporting ATPase activityGO:0154219.7TAP1, TAP2
8peptide antigen bindingGO:0426058.4TAP2, HLA-C, HLA-B, HLA-DRB5, HLA-DRB1, HLA-A

Products for genes affiliated with Alveolar Echinococcosis

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Sources for Alveolar Echinococcosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet