MCID: ALZ008
MIFTS: 19

Alzheimer Disease Risk Factor malady

Summaries for Alzheimer Disease Risk Factor

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32MalaCards
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MalaCards: Alzheimer Disease Risk Factor is related to hereditary cerebral amyloid angiopathy and inclusion body myositis. An important gene associated with Alzheimer Disease Risk Factor is APOE (apolipoprotein E), and among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Neuroscience. The compounds thioflavine s and metrifonate have been mentioned in the context of this disorder. Related mouse phenotype other.

Aliases & Classifications for Alzheimer Disease Risk Factor

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20GeneTests
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Aliases & Descriptions:

alzheimer disease risk factor 20


Related Diseases for Alzheimer Disease Risk Factor

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Alzheimer Disease Risk Factor:



Diseases related to alzheimer disease risk factor

Clinical Features for Alzheimer Disease Risk Factor

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Drugs & Therapeutics for Alzheimer Disease Risk Factor

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Alzheimer Disease Risk Factor

Drug clinical trials:

Search ClinicalTrials for Alzheimer Disease Risk Factor

Search NIH Clinical Center for Alzheimer Disease Risk Factor

Search CenterWatch for Alzheimer Disease Risk Factor

Genetic Tests for Alzheimer Disease Risk Factor

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20GeneTests
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Genetic tests related to Alzheimer Disease Risk Factor:

id Genetic test Affiliating Genes
1 Alzheimer Disease Risk Factor (apoe Genotype)20 APOE

Anatomical Context for Alzheimer Disease Risk Factor

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Animal Models for Alzheimer Disease Risk Factor or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Alzheimer Disease Risk Factor:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053959.1APOE, APP

Publications for Alzheimer Disease Risk Factor

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Genetic Variations for Alzheimer Disease Risk Factor

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Expression for genes affiliated with Alzheimer Disease Risk Factor

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Alzheimer Disease Risk Factor

Search GEO for disease gene expression data for Alzheimer Disease Risk Factor.

Pathways for genes affiliated with Alzheimer Disease Risk Factor

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53Reactome, 29KEGG, 37NCBI BioSystems Database, 4Cell Signaling Technology, 51QIAGEN, 52R&D Systems
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Pathways related to Alzheimer Disease Risk Factor according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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9.1APOE, APP
29.1APOE, APP
39.1APP, APOE
49.1APOE, APP
59.1APOE, APP

Compounds for genes affiliated with Alzheimer Disease Risk Factor

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Sources:
44Novoseek, 11DrugBank, 24HMDB, 49PharmGKB, 28IUPHAR, 2BitterDB, 59Tocris Bioscience
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Compounds related to Alzheimer Disease Risk Factor according to GeneCards/GeneDecks:

(show all 29)
idCompoundScoreTop Affiliating Genes
1thioflavine s449.5APOE, APP
2metrifonate449.5APOE, APP
324s-hydroxy-cholesterol449.5APOE, APP
4thioflavin t449.5APP, APOE
5tacrine44 1110.5APOE, APP
6donepezil44 11 2411.5APOE, APP
7galantamine44 49 1111.5APOE, APP
8formate449.5APP, APOE
9ibuprofen44 28 49 11 2413.5APOE, APP
104-hydroxynonenal44 2410.5APOE, APP
11chloroquine44 2 49 28 1113.5APOE, APP
12lactacystin449.5APP, APOE
13lovastatin44 49 59 28 1113.4APOE, APP
14sodium dodecylsulfate449.4APOE, APP
15simvastatin44 49 59 28 11 2414.4APP, APOE
16folate449.4APOE, APP
17nicotine44 49 28 1112.4APOE, APP
18valine449.4APOE, APP
19vitamin a44 11 2411.4APP, APOE
20aspirin44 49 28 2412.4APOE, APP
21nmda44 2810.3APOE, APP
22acetylcholine44 49 28 11 2413.3APP, APOE
23actinomycin d449.3APOE, APP
24cyclosporin a44 28 5911.2APOE, APP
25glutamine449.2APOE, APP
26dopamine44 28 11 2412.1APP, APOE
27heparin44 28 11 2412.1APOE, APP
28creatinine449.0APOE, APP
29aspartate448.8APOE, APP

GO Terms for genes affiliated with Alzheimer Disease Risk Factor

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16Gene Ontology
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Biological processes related to Alzheimer Disease Risk Factor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cholesterol metabolic processGO:0082039.1APOE, APP

Molecular functions related to Alzheimer Disease Risk Factor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1identical protein bindingGO:0428029.1APOE, APP
2heparin bindingGO:0082018.8APOE, APP

Products for genes affiliated with Alzheimer Disease Risk Factor

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Alzheimer Disease Risk Factor

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet