MCID: ALZ036
MIFTS: 51

Alzheimer Disease, Type 3 malady

Categories: Genetic diseases, Rare diseases, Neuronal diseases, Mental diseases

Aliases & Classifications for Alzheimer Disease, Type 3

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Aliases & Descriptions for Alzheimer Disease, Type 3:

Name: Alzheimer Disease, Type 3 52 12
Ad3 11 48 24 70
Alzheimer Disease Type 3 48 24 27
Alzheimer Disease 3 11 48 70
Familial Alzheimer Disease 3 with Spastic Paraparesis and Apraxia 70 27
Familial Alzheimer Disease 3 with Spastic Paraparesis and Unusual Plaques 70
Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual Plaques 52
Alzheimer Disease, Type 3, with Spastic Paraparesis and Apraxia 52
 
Early-Onset Familial Alzheimer Disease 3 70
Alzheimer Disease Early Onset Type 3 48
Alzheimer Disease, Familial, Type 3 68
Alzheimer Disease 3, Early Onset 11
Familial Alzheimer Disease 3 70
Alzheimer Disease Familial 3 11
Alzheimer's Disease 3 11
Ad 3 24

Characteristics:

HPO:

64
alzheimer disease, type 3:
Inheritance: autosomal dominant inheritance
Onset and clinical course: adult onset, rapidly progressive

Classifications:



External Ids:

OMIM52 607822
Disease Ontology11 DOID:0110042
MeSH39 D000544

Summaries for Alzheimer Disease, Type 3

About this section
UniProtKB/Swiss-Prot:70 Alzheimer disease 3: A familial early-onset form of Alzheimer disease. Alzheimer disease is a neurodegenerative disorder characterized by progressive dementia, loss of cognitive abilities, and deposition of fibrillar amyloid proteins as intraneuronal neurofibrillary tangles, extracellular amyloid plaques and vascular amyloid deposits. The major constituent of these plaques is the neurotoxic amyloid-beta-APP 40-42 peptide (s), derived proteolytically from the transmembrane precursor protein APP by sequential secretase processing. The cytotoxic C-terminal fragments (CTFs) and the caspase-cleaved products such as C31 derived from APP, are also implicated in neuronal death.

MalaCards based summary: Alzheimer Disease, Type 3, also known as ad3, is related to hyperlipidemia type 3 and multiple enchondromatosis, maffucci type, and has symptoms including dementia, personality changes and seizures. An important gene associated with Alzheimer Disease, Type 3 is PSEN1 (Presenilin 1), and among its related pathways are Notch signaling pathway (KEGG) and Neuroscience. Affiliated tissues include brain, testes and breast.

Disease Ontology:11 An Alzheimer's disease that has material basis in mutation in the presenilin-1 gene (PSEN1) on chromosome 14q24.

Description from OMIM:52 607822

Related Diseases for Alzheimer Disease, Type 3

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Graphical network of diseases related to Alzheimer Disease, Type 3:



Diseases related to alzheimer disease, type 3

Symptoms & Phenotypes for Alzheimer Disease, Type 3

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Symptoms by clinical synopsis from OMIM:

607822

Clinical features from OMIM:

607822

Human phenotypes related to Alzheimer Disease, Type 3:

 64 (show all 18)
id Description HPO Frequency HPO Source Accession
1 dementia64 HP:0000726
2 personality changes64 HP:0000751
3 seizures64 HP:0001250
4 dysarthria64 HP:0001260
5 spastic tetraparesis64 HP:0001285
6 gait disturbance64 HP:0001288
7 dystonia64 HP:0001332
8 myoclonus64 HP:0001336
9 dysphagia64 HP:0002015
10 abnormality of extrapyramidal motor function64 HP:0002071
11 cerebral cortical atrophy64 HP:0002120
12 neurofibrillary tangles64 HP:0002185
13 apraxia64 HP:0002186
14 memory impairment64 HP:0002354
15 lower limb hyperreflexia64 HP:0002395
16 alzheimer disease64 HP:0002511
17 babinski sign64 HP:0003487
18 agnosia64 HP:0010524

UMLS symptoms related to Alzheimer Disease, Type 3:


myoclonus, seizures, extrapyramidal sign, personality change, memory loss

Drugs & Therapeutics for Alzheimer Disease, Type 3

About this section

Drugs for Alzheimer Disease, Type 3 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 182)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
DonepezilapprovedPhase 4, Phase 3, Phase 2280120014-06-43152
Synonyms:
( inverted exclamation markA)-E 2020
1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine
120014-06-4
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one
AB1004836
AC-6969
AC1L1FAE
AKOS000277311
Aricept
Aricept ODT
C24H29NO3
CHEBI:53289
CHEMBL502
CID3152
D07869
DB00843
Domepezil
Donaz
Donaz (TN)
 
Donepezil
Donepezil (INN)
Donepezil [INN:BAN]
Donepezil hydrochloride
Donepezilo
Donepezilum
Eranz
I06-0343
KBio2_002144
KBio2_004712
KBio2_007280
KBioSS_002144
LS-81819
MolPort-000-881-588
MolPort-003-847-014
NCGC00167537-01
Oprea1_188452
Spectrum5_001662
Spectrum_001664
TL8000531
UNII-8SSC91326P
2
Memantineapproved, investigationalPhase 4, Phase 317619982-08-24054
Synonyms:
1,3-Dimethyl-5-adamantanamine
1-Amino-3,5-dimethyladamantane
19982-08-2
3,5-Dimethyl-1-adamantanamine
3,5-Dimethyl-1-adamantylamine
3,5-Dimethyl-1-aminoadamantane
3,5-Dimethyladamantan-1-ylamine
3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
3,5-dimethyladamantan-1-amine
3,5-dimethyltricyclo[3.3.1.1~3,7~]decan-1-amine
41100-52-1 (Hydrochloride)
51052-62-1
AB00053600
AC1L1HB7
AKOS000113995
BBL000737
BPBio1_001117
BPBio1_001270
BSPBio_001015
Biomol-NT_000209
C13736
CBMicro_020348
CHEBI:152523
CHEMBL807
CID4054
D08174
DB01043
DMAA
DivK1c_000068
EU-0053634
Ebixa
Exiba
Exiba (TN)
HMS500D10
HSDB 7327
IDI1_000068
KBio1_000068
KBio2_001087
KBio2_003655
 
KBio2_006223
KBio3_001926
KBioGR_001543
KBioSS_001087
LS-157051
Lopac0_000861
Memantin
Memantina
Memantina [INN-Spanish]
Memantine
Memantine (INN)
Memantine HCL
Memantine Hydrochloride
Memantine [INN:BAN]
Memantine [INN]
Memantinum
Memantinum [INN-Latin]
MolPort-002-041-858
NCGC00015705-05
NCGC00024782-02
NCGC00024782-03
NINDS_000068
Namenda
Oprea1_480562
Prestwick0_000978
Prestwick1_000978
Prestwick2_000978
Prestwick3_000978
SPBio_001456
SPBio_002926
ST057652
STK520682
Spectrum2_001408
Spectrum3_000923
Spectrum4_001022
Spectrum5_001355
Spectrum_000607
UNII-W8O17SJF3T
ZERO/006024
memantine
3
Rivastigmineapproved, investigationalPhase 4, Phase 383123441-03-277991
Synonyms:
(S)-3-(1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate
123441-03-2
3-((1S)-1-(Dimethylamino)ethyl)phenyl N-ethyl-N-methylcarbamate
3-((1S)-1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate
3-[(1S)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate
AB1004572
AC1L2U92
BIDD:GT0316
C11766
CHEMBL636
CID77991
Carbamic acid, N-ethyl-N-methyl-, 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester
Carbamic acid, ethylmethyl-, 3-((1S)-1-(dimethylamino)ethyl)phenyl ester
D03822
DB00989
ENA 713 free base
 
Ena 713 Free Base
Ethylmethylcarbamic acid 3-((1S)-1-(dimethylamino)ethyl)phenyl ester
Exelon
Exelon Patch
HMS2089H18
I06-2037
LS-172571
MolPort-003-666-662
NCGC00167531-01
Rivastigmine (JAN/USAN/INN)
Rivastigmine Hydrogen Tartrate
Rivastigmine [USAN:INN]
Rivastigmine hydrogen tartrate
SDZ 212-713
UNII-PKI06M3IW0
[3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate
m-((S)-1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate
rivastigmine
4
DipivefrinapprovedPhase 49452365-63-63105
Synonyms:
( -)-2,2-Dimethylpropansaeure-4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylenester
( -)-4-(1-Hydroxy-2-methylaminoethyl)-o-phenylendipivalat
(+-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol 3,4-dipivalate
(+-)-4-[1-Hydroxy-2-(methylamino)ethyl]-O-phenylene divavalate
(+-)-4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate
(RS)-4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylen dipivalat
1-(3',4'-Dipivaloyloxyphenyl)-2-methylamino-1-ethanol
1-(3',4'-dipivaloyloxyphenyl)-2-methylamino-1-ethanol
2,2-Dimethylpropanoic acid 4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene ester
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylen dipivalat
4-[1-Hydroxy-2-(methylamino)ethyl]-O-phenylene divavalate
4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate
4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diyl bis(2,2-dimethylpropanoate)
52365-63-6
AB00514686
AC1L1F6K
AKOS003662293
AKPro
BPBio1_000688
BRD-A47494775-003-03-0
BSPBio_000624
C06963
C19H29NO5
CHEBI:4646
CID3105
D02349
DB00449
Dipivalyl Epinephrine
 
Dipivefrin
Dipivefrin (USAN)
Dipivefrin HCL
Dipivefrin [USAN]
Dipivefrina
Dipivefrina [INN-Spanish]
Dipivefrine
Dipivefrine (INN)
Dipivefrinum
Dipivefrinum [INN-Latin]
Dipivéfrine
K 30081
L000915
LS-121419
NCGC00179499-01
Ophtho-Dipivefrin
Prestwick0_000632
Prestwick1_000632
Prestwick2_000632
Prestwick3_000632
Pro-Epinephrine
Propine
Propine C Cap B.I.D.
SPBio_002843
UNII-8Q1PVL543G
[2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate
dipivalyl epinephrine
dipivefrin
nchembio747-comp3
5
BenzocaineapprovedPhase 4, Phase 218921994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthone
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Bensokain
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Caswell No. 430A
Chloraseptic
D001566
D00552
DB01086
Dermoplast
Diet Ayds
DivK1c_000932
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
 
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Formate, Benzocaine
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Hurricaine
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Keloform
LS-35847
MLS001331704
MLS002153970
Methanesulfonate, Benzocaine
MolPort-000-871-526
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Norcain
Norcaine
Norcainum
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orthesin
Otocain
Outgro
Parathesin
Parathesin (TN)
Parathesine
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Topcaine
UNII-U3RSY48JW5
WLN: ZR DVO2
ZINC12358719
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
6
DopamineapprovedPhase 4, Phase 3375951-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
7
Dexamethasoneapproved, investigational, vet_approvedPhase 4208450-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
 
Dexameth
Dexamethansone
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
8
OndansetronapprovedPhase 430999614-02-54595
Synonyms:
(RS)-1,2,3,9-Tetrahydro-9-methyl-3-(2-methylimidazol-1-ylmethyl)carbazol-4-one
1,2,3,9-Tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-4H-carbazol-4-one
103639-04-9 (mono-hydrochloride dihydrate)
108303-49-7
116002-70-1
9-Methyl-3-(2-methyl-imidazol-1-ylmethyl)-1,2,3,9-tetrahydro-carbazol-4-one
9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one
9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4-one
99614-01-4 (mono-hydrochloride)
99614-02-5
AB00373674
AC1L1IIM
AKOS000599484
Apo-ondansetron
BAS 00717177
BPBio1_001118
BRD-A19736161-001-01-8
BRD-A19736161-003-03-0
BRN 3622981
BSPBio_001016
C07325
C18H19N3O
CBDivE_008994
CHEMBL46
CID4595
CPD001307702
D00456
DB00904
DESMETHYLONDANSETRON
GR 38032
GR 38032X
GR-38032F
GR38032F
HMS2090H16
I06-0687
I06-1329
 
L000456
LS-172305
LS-51878
MolPort-001-944-253
NCI60_022780
Novo-ondansetron
Ondansetron
Ondansetron (JAN/USP/INN)
Ondansetron [USAN:INN:BAN]
Ondansetron, (+,-)-Isomer
Oprea1_435466
Oprea1_852372
PHL-ondansetron
PMS-ondansetron
Prestwick0_001058
Prestwick1_001058
Prestwick2_001058
Prestwick3_001058
Ratio-ondansetron
SAM002589958
SN-307
SPBio_002938
STK370548
STOCK4S-10990
Sandoz ondansetron
TL8006071
TimTec1_001750
UNII-4AF302ESOS
ZOFRAN IN PLASTIC CONTAINER
Zofran
Zofran ODT
Zofran ODT (TN)
Zofran odt
Zophren
Zudan
ondansetron
ondansetron (Zofran)
9
Sevofluraneapproved, vet_approvedPhase 447928523-86-65206
Synonyms:
1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane
28523-86-6
AC-15484
AC1L1JU0
BRN 2041023
Bax 3084
C009250
C07520
C4H3F7O
CHEBI:9130
CHEMBL1200694
CID5206
D00547
DB01236
F0691
Fluoromethyl 1,1,1,3,3,3-Hexafluoroisopropyl Ether
Fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
I14-13357
LS-67851
MR6S4
 
MR_6S4
MolPort-001-775-746
NCGC00167421-01
PC4681
Sevofluran
Sevoflurane
Sevoflurane (JAN/USAN/INN)
Sevoflurane [USAN:INN:BAN:JAN]
Sevoflurano
Sevoflurano [INN-Spanish]
Sevofluranum
Sevofluranum [INN-Latin]
Sevofrane
Sevorane
Sojourn
UNII-38LVP0K73A
Ultane
Ultane (TN)
ZINC01530810
fluoromethyl hexafluoroisopropyl ether
fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
sevoflurane
10
AcetaminophenapprovedPhase 4978103-90-21983
Synonyms:
4'-Hydroxyacetanilide
4'-hydroxyacetanilide
4-(Acetylamino)phenol
4-Acetamidophenol
4-Acetaminophenol
4-Hydroxyacetanilide
4-Hydroxyanilid kyseliny octove
4-acetamidophenol
A-Per
A.F. Anacin
AC1Q1KYJ
AC1Q1KYK
APAP
Abenol
Abensanil
Abrol
Abrolet
Acamol
Accu-Tap
Acenol
Acephen
Acertol
Aceta Elixir
Aceta Tablets
Acetaco
Acetagesic
Acetalgin
Acetaminofen
Acetaminophen
Acetaminophen Uniserts
Acetamol
Acetavance
Acetofen
Actamin
Actamin Extra
Actamin Super
Actifed Plus
Actimol
Actimol Chewable Tablets
Actimol Children'S Suspension
Actimol Infants' Suspension
Actimol Junior Strength Caplets
Actron
Afebrin
Afebryl
Aferadol
Algesidal
Algina
Algomol
Algotropyl
Allay
Alpiny
Alpinyl
Alvedon
Amadil
Aminofen
Aminofen Max
Anacin
Anacin 3
Anacin-3
Anacin-3 Extra Strength
Anadin dla dzieci
Anaflon
Analter
Anapap
Andox
Anelix
Anexsia
Anexsia 10/660
Anexsia 5/325
Anexsia 7.5/325
Anexsia 7.5/650
Anhiba
Anoquan
Anti-Algos
Antidol
Anuphen
Apacet
Apacet Capsules
Apacet Elixir
Apacet Extra Strength Caplets
Apacet Extra Strength Tablets
Apacet Regular Strength Tablets
Apadon
Apamid
Apamide
Apitrelal
Apo-Acetaminophen
Arfen
Arthralgen
Asetam
Asomal
Aspac
Aspirin Free Anacin Maximum Strength Caplets
Aspirin Free Anacin Maximum Strength Gel Caplets
Aspirin Free Anacin Maximum Strength Tablets
Aspirin-Free Anacin
Aspirin-Free Excedrin Caplets
Asplin
Atasol
Atasol Caplets
Atasol Drops
Atasol Forte Caplets
Atasol Forte Tablets
Atasol Oral Solution
Atasol Tablets
Atralidon
Babikan
Bacetamol
Bancap
Bancap Hc
Banesin
Bayer Select
Bayer Select Allergy-Sinus
Bayer Select Head Cold
Bayer Select Headache Pain
Bayer Select Maximum Strength Headache Pain Relief Formula
Bayer Select Menstrual Multi-Symptom
Bayer Select Sinus Pain Relief
Ben-u-ron
Benmyo
Bickie-mol
Biocetamol
Bucet
Butalbital
Butapap
CCRIS 3
CHEBI:46195
Cadafen
Calapol
Calmanticold
Calonal
Calpol
Capital
Capital with Codeine
Captin
Causalon
Cefalex
Cetadol
Children'S Acetaminophen Elixir Drops
Children'S Acetaminophen Oral Solution
Children'S Tylenol Chewable
Claradol Codeine
Clixodyne
Co-Gesic
Cod-Acamol Forte
Codabrol
Codalgin
Codapane
Codicet
Codisal
Codisal Forte
Codoliprane
Codral Pain Relief
Cofamol
Conacetol
Contac Cough & Sore Throat Formula
Contra-Schmerz P
Coricidin
Coricidin D
Coricidin Sinus
Cosutone
Croix Blanche
Cuponol
Curadon
Curpol
Custodial
D oliprane
Dafalgan
Dapa
Dapa X-S
Darocet
Darvocet
Darvocet-N 50
Datril
Datril Extra-Strength
Daygrip
Demilets
Deminofen
Democyl
Demogripal
Desfebre
Dhamol
Dhc Plus
Dial-a-gesic
Dial-alpha-gesic
Dimindol
Dirox
Disprol
Dol-Stop
Dolcor
Dolefin
Dolegrippin
Dolene AP-65
Dolene Ap-65
Dolgesic
Doliprane
Dolko
Dolofugin
Doloreduct
Dolorfug
Dolorol Forte
Dolorstop
Dolotec
Dolprone
Dorocoff
Dresan
Dristan Cold No Drowsiness
Dristancito
Drixoral Plus
Duaneo
Dularin
Duorol
Duracetamol
Duradyne Dhc
Durapan
Dymadon
Dymadon Co
Dymadon Forte
Dypap
Ecosetol
Elixodyne
Empracet
Endecon
Enelfa
Eneril
Esgic
Esgic-Plus
Eu-Med
Excedrin
Excedrin Caplets
Excedrin Extra Strength Caplets
Excipain
Exdol
Exdol Strong
Fanalgic
Farmadol
Febranine
Febrectal
Febrectol
Febrex
Febricet
Febridol
Febrilix
Febrin
Febrinol
Febro-Gesic
Febrolin
Femcet
Fendon
Fensum
Fepanil
Fever All
Feverall
Feverall Junior Strength
Feverall Sprinkle Caps Junior Strength
Fevor
Finimal
Finiweh
Fioricet
Fluparmol
Fortalidon P
Freka-cetamol
Gattaphen T
Gelocatil
Geluprane
Genapap
Genapap Children'S Elixir
Genapap Children'S Tablets
Genapap Extra Strength Caplets
Genapap Extra Strength Tablets
Genapap Regular Strength Tablets
Genebs
Genebs Extra Strength Caplets
Genebs Regular Strength Tablets
Genebs X-Tra
Geralgine-P
Gripin Bebe
Grippostad
Gynospasmine
Hedex
Helon N
Homoolan
Hy-Phen
Hycomine Compound
Hydrocet
Ildamol
Inalgex
Infadrops
Infants' Feverall
Influbene N
Injectapap
Intensin
Janupap
Jin Gang
Junior Disprol
KBio1_000660
Kataprin
Kinder Finimal
Korum
Kratofin simplex
L024125
Labamol
Lekadol
Lemgrip
Lemsip
Lestemp
Liqiprine
Liquagesic
Liquigesic Co
Liquiprin
Liquiprin Children'S Elixir
Liquiprin Infants" Drops
Lonarid
Lonarid Mono
Lorcet-Hd
Lortab
Lupocet
Lyteca
Lyteca Syrup
Magnidol
Malex N
Malgis
Malidens
Maxadol
Medigesic Plus
Medinol Paediatric
Medocodene
Melabon Infantil
Mexalen
Midol Maximum Strength
Midol PM Night Time Formula
Midol Regular Strength
Midol Teen Formula
Migraleve Yellow
Minafen
Minoset
Miralgin
Momentum
Mono Praecimed
 
Multin
N-(4-Hydroxyphenyl)acetamide
N-Acetyl-4-aminophenol
N-Acetyl-p-aminophenol
N-acetyl-p-aminophenol
NAPA
NCX 701
NEBS
NSC3991
Naldegesic
Napafen
Napap
Naprinol
Nealgyl
Nebs
Neo-Fepramol
NeoCitran
Neodol
Neodolito
Neopap
Neotrend
Neuridon
New Cortal for Children
NilnOcen
Nina
No-Febril
Nobedon
Nodolex
Noral
Norcet
Norco
O-Acetaminophenol
Ofirmev
Oltyl
Oralgan
Oraphen-PD
Ortensan
Oxycet
Oxycocet
Oxycodone 2.5/Apap 500
Oxycodone 5/Apap 500
PCM Paracetamol Lichtenstein
Paceco
Pacemo
Pacemol
Pacet
Pacimol
Paedialgon
Paedol
Painex
Paldesic
Pamol
Panacete
Panadeine
Panadeine Co
Panadiene
Panado-Co
Panado-Co Caplets
Panadol
Panadol Extra Strength
Panadol Junior Strength Caplets
Panadol Maximum Strength Caplets
Panadol Maximum Strength Tablets
Panale ve
Panaleve
Panamax
Panasorb
Panasorbe
Panets
Panex
Panodil
Panofen
Pantalgin
Papa-Deine
Papa-Deine #3
Papa-Deine #4
Para-Suppo
Para-Tabs
Paracemol
Paracenol
Paracet
Paracetamol
Paracetamol AL
Paracetamol Antipanin P
Paracetamol BC
Paracetamol Basics
Paracetamol DC
Paracetamol Dr. Schmidgall
Paracetamol Fecofar
Paracetamol Genericon
Paracetamol Hanseler
Paracetamol Harkley
Paracetamol Heumann
Paracetamol Hexal
Paracetamol Italfarmaco
Paracetamol Nycomed
Paracetamol PB
Paracetamol Raffo
Paracetamol Ratiopharm
Paracetamol Rosch
Paracetamol Saar
Paracetamol SmithKline Beecham
Paracetamol Stada
Paracetamol Winthrop
Paracetamol von ct
Paracetamole
Paracetamolo
Paracetamolum
Paracetanol
Paracetol
Paracin
Paracod
Paracodol
Paracétamol
Parador
Paradrops
Parakapton
Parake
Paralen
Paralief
Paralink
Paralyoc
Paramol
Paramolan
Paranox
Parapan
Parasedol
Parasin
Paraspen
Parcetol
Parelan
Parmol
Parogal
Paroma
Pasolind
Pasolind N
Pe-Tam
Pediapirin
Pediatrix
Pedric
Percocet
Percocet-5
Percocet-Demi
Percogesic with Codeine
Perdolan Mono
Perfalgan
Phenaphen
Phenaphen Caplets
Phenaphen W/Codeine
Phendon
Phenipirin
Phogoglandin
Phrenilin
Phrenilin Forte
Pinex
Piramin
Pirinasol
Plicet
Polmofen
Predimol
Predualito
Prestwick_13
Prodol
Prompt
Prontina
Propacet
Propacet 100
Proval #3
Puernol
Pulmofen
Pyregesic-C
Pyrigesic
Pyrinazine
Pyromed
Quiet World
Redutemp
Reliv
Remedol
Rhinex D-Lay Tablets
Rivalgyl
Robigesic
Robitussin Night Relief
Rockamol Plus
Rounox
Roxicet
Roxicet 5/500
Roxilox
RubieMol
Rubophen
Rupemol
SK-Apap
SPBio_002836
Salzone
Sanicet
Sanicopyrine
Scanol
Scentalgyl
Scherzatabletten Rezeptur 534
Schmerzex
Sedalito
Sedapap
Semolacin
Servigesic
Seskamol
Setakop
Setamol
Setol
Sifenol
Sinaspril
Sine-Off Sinus Medicine Caplets
Sinedol
Sinmol
Sinubid
Snaplets-FR
Spalt N
Spalt fur die nacht
St Joseph Aspirin-Free
St Joseph Aspirin-Free for Children
St. Joseph Cold Tablets for Children
St. Joseph Fever Reducer
Stanback
Stopain
Sudafed Severe Cold Formula
Sudafed Sinus
Sunetheton
Supac
Supadol mono
Supofen
Suppap
Suppap-120
Suppap-325
Suppap-650
Supramol-M
Synalgos-Dc-A
TYL
Tabalgin
Tachiprina
Talacen
Tapanol
Tapanol Extra Strength Caplets
Tapanol Extra Strength Tablets
Tapar
Tavist Allergy/Sinus/Headache
Tazamol
Temlo
Tempanal
Tempra
Tempra Caplets
Tempra Chewable Tablets
Tempra D.S
Tempra Drops
Tempra Syrup
Tencon
Termacet
Termalgin
Termalgine
Termofren
TheraFlu
Tibinide
Tibizide
Tiffy
Tisin
Tisiodrazida
Titralgan
Tizide
Tocris-1706
Toximer P
Tralgon
Treupel N
Treupel mon
Treuphadol
Triad
Triaminic Sore Throat Formula
Triaprin
Tricoton
Tussapap
Ty lenol
Tycolet
Tylenol
Tylenol (TN)
Tylenol Allergy Sinus
Tylenol Arthritis Extended Relief
Tylenol Caplets
Tylenol Children'S Chewable Tablets
Tylenol Children'S Elixir
Tylenol Children'S Suspension Liquid
Tylenol Drops
Tylenol Elixir
Tylenol Extra Strength Adult Liquid Pain Reliever
Tylenol Extra Strength Caplets
Tylenol Extra Strength Gelcaps
Tylenol Extra Strength Tablets
Tylenol Gelcaps
Tylenol Infants Drops
Tylenol Infants" Suspension Drops
Tylenol Junior Strength Caplets
Tylenol Junior Strength Chewable Tablets
Tylenol Regular Strength Caplets
Tylenol Regular Strength Tablets
Tylenol Tablets
Tylex
Tylex CD
Tylol
Tylox
Tylox-325
Tymol
Ultracet
Upsanol
Utragin
Valadol
Valgesic
Valorin
Valorin Extra
Vanquish
Veralgina
Vermidon
Verpol
Viclor Richet
Vicodin
Vicodin Es
Vicodin Hp
Vips
Viruflu
Vivimed
Volpan
Wygesic
Zatinol
Zolben
acetaminofén
acétaminophène
alpha-Per
p-(Acetylamino)phenol
p-Acetamidophenol
p-Acetaminophenol
p-Acetylaminophenol
p-Hydroxyacetanilide
p-Hydroxyphenolacetamide
p-acetamidophenol
p-acetaminophenol
p-hydroxy-acetanilid
p-hydroxyacetanilide
p-hydroxyphenolacetamide
11
MetforminapprovedPhase 41746657-24-914219, 4091
Synonyms:
1,1-Dimethyl biguanide
1,1-Dimethylbiguanide
3-(diaminomethylidene)-1,1-dimethylguanidine
657-24-9
AC1L1HE4
AKOS000121065
Apo-Metformin
BIDD:GT0697
BPBio1_000009
BRD-K79602928-003-04-1
BSPBio_000007
BSPBio_002314
C07151
C4H11N5
CAS-1115-70-4
CCRIS 9321
CHEBI:6801
CHEMBL1431
CID4091
D04966
DB00331
DMGG
Diabetosan
Diabex
Dimethylbiguanid
Dimethylbiguanide
Dimethylbiguanidine
Dimethyldiguanide
Dimethylguanylguanidine
EINECS 211-517-8
Fluamine
Flumamine
Fortamet
Gen-Metformin
Glifage
Gliguanid
Glucophage
Glucophage XR
Glumetza
Glycon
HMS2089D19
HSCI1_000295
Haurymelin
Haurymellin
Islotin
KBio2_002310
KBio2_004878
KBio2_007446
KBio3_002790
KBioGR_002310
 
KBioSS_002312
LA-6023
LS-43899
Melbin
Metformin
Metformin (USAN/INN)
Metformin HCL
Metformin [USAN:INN:BAN]
Metformina
Metformina [DCIT]
Metformina [Spanish]
Metformine
Metformine [INN-French]
Metformine pamoate
Metforminum
Metforminum [INN-Latin]
Metiguanide
MolPort-002-929-560
MolPort-004-288-389
MolPort-005-767-418
Mylan-Metformin
N,N-Dimethylbiguanide
N,N-Dimethyldiguanide
N,N-Dimethylimidodicarbonimidic diamide
N,N-dimethylimidodicarbonimidic diamide
N1,N1-Dimethylbiguanide
NCGC00016564-01
NCGC00016564-02
NCGC00016564-03
NNDG
Novo-Metformin
Nu-Metformin
PMS-Metformin
Prestwick0_000004
Prestwick1_000004
Prestwick2_000004
Prestwick3_000004
Ran-Metformin
Ratio-Metformin
Riomet
S2483_Selleck
SPBio_001928
STK011633
Sandoz Metformin
Siofor
T5895664
Teva-Metformin
UNII-9100L32L2N
ZINC12859773
cMAP_000016
metformin
metformin hydrochloride
12
Vitamin Capproved, nutraceuticalPhase 451450-81-75785, 54670067
Synonyms:
(+)-Sodium L-ascorbate
(+)-ascorbate
(+)-ascorbic acid
(2R)-2-[(1S)-1,2-Dihydroxyethyl]-4,5-dihydroxy-furan-3-one
(2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one
(5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one
129940-97-2
134-03-2 (monosodium salt)
14536-17-5
154170-90-8
2-(1,2-Dihydroxyethyl)-4,5-dihydroxyfuran-3-one
255564_SIAL
259133-78-3
3-Keto-L-gulofuranolactone
3-Oxo-L-gulofuranolactone
3-Oxo-L-gulofuranolactone (enol form)
30208-61-8
33034_RIEDEL
33034_SIAL
47863_SUPELCO
47A605F0-4187-47A8-B0CE-F9E7DA1B0076
50-81-7
50976-75-5
56172-55-5
56533-05-2
57304-74-2
57606-40-3
623158-95-2
6730-29-6
882690-91-7
884381-69-5
885512-24-3
88845-26-5
89924-69-6
95209_FLUKA
95209_SIGMA
95210_FLUKA
95210_SIAL
95212_FLUKA
A0278_SIGMA
A0537
A2174_SIGMA
A2218_SIGMA
A2343_SIGMA
A4403_SIGMA
A4544_SIGMA
A5960_SIGMA
A7506_SIGMA
A92902_ALDRICH
A92902_SIAL
AA
AB00376923
AB1002440
AC1L1L4T
AC1Q77S6
AR-1J3435
Acid Ascorbic
Acide ascorbique
Acide ascorbique [INN-French]
Acido ascorbico
Acido ascorbico [INN-Spanish]
Acidum ascorbicum
Acidum ascorbicum [INN-Latin]
Acidum ascorbinicum
Adenex
Allercorb
Ambap36431-82-0
Antiscorbic Vitamin
Antiscorbic vitamin
Antiscorbutic Vitamin
Antiscorbutic factor
Antiscorbutic vitamin
Arco-Cee
Arco-cee
Ascoltin
Ascoltin (TN)
Ascor-B.I.D.
Ascorb
Ascorbajen
Ascorbate
Ascorbic Acid
Ascorbic Acid, Monosodium Salt
Ascorbic acid
Ascorbic acid (JP15/USP/INN)
Ascorbic acid [BAN:INN:JAN]
Ascorbic acid [INN:BAN:JAN]
Ascorbicab
Ascorbicap
Ascorbicap (TN)
Ascorbicin
Ascorbin
Ascorbinsaeure
Ascorbinsäure
Ascorbutina
Ascorbyl radical
Ascorin
Ascorteal
Ascorvit
BPBio1_000363
BSPBio_000329
C-Level
C-Long
C-Quin
C-Span
C-Vimin
C00072
C6H8O6
CCRIS 57
CE-VI-Sol
CHEBI:29073
CHEMBL196
CID5785
Cantan
Cantaxin
Caswell No. 061B
Catavin C
Ce Lent
Ce lent
Ce-Mi-Lin
Ce-mi-lin
Ce-vi-sol
Cebicure
Cebid
Cebion
Cebione
Cecon
Cee-Caps TD
Cee-Caps Td
Cee-Vite
Cee-caps TD
Cee-vite
Cegiolan
Ceglion
Ceklin
Celaskon
Celin
Cell C
Cemagyl
Cemill
Cenetone
Cenolate
Cereon
Cergona
Cescorbat
Cetamid
Cetane
Cetane-Caps TC
Cetane-Caps TD
Cetane-Caps Tc
Cetane-Caps Td
Cetane-caps TC
Cetane-caps TD
Cetebe
 
Cetemican
Cevalin
Cevatine
Cevex
Cevi-Bid
Cevi-bid
Cevimin
Cevital
Cevitamate
Cevitamic Acid
Cevitamic acid
Cevitamin
Cevitan
Cevitex
Cewin
Chewcee
Ciamin
Cipca
Citriscorb
Citrovit
Colascor
Concemin
Cortalex
D00018
DB00126
Davitamon C
Dora-C-500
Duoscorb
EINECS 200-066-2
FEMA No. 2109
Ferancee
Ferrous ascorbate
HSDB 818
HiCee
Hicee
Hybrin
IDO-C
Ido-C
Iron(II) ascorbate
Iron-ascorbic acid complexes
Juvamine
Kangbingfeng
Kyselina Askorbova
Kyselina askorbova
Kyselina askorbova [Czech]
L(+)-Ascorbate
L(+)-Ascorbic acid
L-(+)-Ascorbate
L-(+)-Ascorbic Acid
L-(+)-Ascorbic acid
L-(+)-ascorbic acid
L-3-Ketothreohexuronic acid lactone
L-3-ketothreohexuronic acid
L-Ascorbate
L-Ascorbic Acid
L-Ascorbic acid
L-Ascorbic acid, free radical form
L-Lyxoascorbate
L-Lyxoascorbic Acid
L-Lyxoascorbic acid
L-Threo-ascorbic acid
L-Threoascorbic acid
L-Xyloascorbate
L-Xyloascorbic Acid
L-Xyloascorbic acid
L-ascorbate
L-threo-Hex-2-enonic acid, gamma-lactone
L-threo-ascorbic acid
L-threo-hex-2-enono-1,4-lactone
LS-145
Laroscorbine
Lemascorb
Liqui-Cee
Liqui-cee
MLS002153776
Magnesium Ascorbicum
Magnorbin
Meri-C
Meri-c
MolPort-001-792-501
Monodehydroascorbic acid
NCGC00091517-01
NCGC00091517-02
NCGC00164357-01
NCI-C54808
NSC 33832
Natrascorb
Natrascorb injectable
Oral Vitamin C
Planavit C
Prestwick3_000325
Proscorbin
Redoxon
Ribena
Ronotec 100
Rontex 100
Roscorbic
Rovimix C
SMR001233160
Scorbacid
Scorbu C
Scorbu-C
Secorbate
Semidehydroascorbate
Sodascorbate
Sodium Ascorbate (Ascorbic Acid)
Stuartinic
Suncoat VC 40
Sunkist
Testascorbic
Tolfrinic
UNII-PQ6CK8PD0R
VASC
Vicelat
Vicin
Vicomin C
Viforcit
Viscorin
Viscorin 100M
Vitace
Vitacee
Vitacimin
Vitacin
Vitamin C
Vitamin- C
Vitamin-?C
Vitamisin
Vitascorbol
W210901_ALDRICH
Xitix
acide ascorbique
acidum ascorbicum
acidum ascorbinicum
antiscorbic vita min
ascor-b.i.d
ascorbate
ascorbic acid
bmse000182
cee-caps td
cevibid
component of Cortalex
component of E and C-Level
component of Endoglobin Forte
component of Ferancee
gamma-Lactone L-threo-Hex-2-enonate
gamma-Lactone L-threo-Hex-2-enonic acid
l-ascorbic acid
l-threo-hex-1-eofuranos-3-ulose
nchembio.174-comp5
nchembio.89-comp1
nchembio.92-comp2
nchembio821-comp9
roscorbi c
vitamin C
ácido ascórbico
13tannic acidapproved, NutraceuticalPhase 4, Phase 21892
14Cholinergic AgentsPhase 4, Phase 3, Phase 23846
15Cholinesterase InhibitorsPhase 4, Phase 3, Phase 2570
16Nootropic AgentsPhase 4, Phase 3, Phase 2701
17Neurotransmitter AgentsPhase 4, Phase 3, Phase 217734
18MicronutrientsPhase 4, Phase 25802
19AntioxidantsPhase 42928
20Protective AgentsPhase 4, Phase 37190
21Trace ElementsPhase 4, Phase 25802
22XenonPhase 466
23VitaminsPhase 4, Phase 25095
24Excitatory Amino Acid AntagonistsPhase 4, Phase 31282
25Insulin, Globin ZincPhase 4, Phase 24523
26AnalgesicsPhase 4, Phase 311287
27Analgesics, Non-NarcoticPhase 4, Phase 36260
28insulinPhase 4, Phase 24524
29Hypoglycemic AgentsPhase 4, Phase 3, Phase 25733
30Dopamine AgentsPhase 4, Phase 33759
31Tranquilizing AgentsPhase 4, Phase 3, Phase 24164
32Excitatory Amino AcidsPhase 4, Phase 31297
33Antiparkinson AgentsPhase 4, Phase 31527
34Neuroprotective AgentsPhase 4, Phase 31672
35Antipsychotic AgentsPhase 4, Phase 32359
36AntipruriticsPhase 4864
37Autonomic AgentsPhase 4, Phase 39774
38BB 1101Phase 42084
39Dermatologic AgentsPhase 45674
40Central Nervous System DepressantsPhase 4, Phase 3, Phase 212806
41Anti-Inflammatory AgentsPhase 4, Phase 310355
42AntiemeticsPhase 43888
43AnestheticsPhase 4, Phase 39001
44Serotonin AntagonistsPhase 41381
45Anesthetics, GeneralPhase 42787
46Anesthetics, InhalationPhase 4649
47Anti-Anxiety AgentsPhase 41816
48Dexamethasone 21-phosphatePhase 42084
49Antineoplastic Agents, HormonalPhase 45407
50
protease inhibitorsPhase 4, Phase 2, Phase 35320
Synonyms:
 
protease inhibitors

Interventional clinical trials:

(show top 50)    (show all 142)
idNameStatusNCT IDPhase
1Visual Function With Bilateral AcrySof® ReSTOR® Aspheric SN6AD1CompletedNCT00710931Phase 4
2Visual Performance After RESTOR ImplantationCompletedNCT01065064Phase 4
3Visual Acuity After the Combined Binocular Implantation of +2.5 Diopters and +3.0 Diopters ReSTOR Multifocal Intraocular Lenses.CompletedNCT02314572Phase 4
4Depth of Hypnosis and Postoperative Nausea and Vomiting During Xenon AnaesthesiaCompletedNCT00793663Phase 4
5ACRYSOF® ReSTOR® Aspheric +3.0 D Add Power Intraocular Lens (IOL)CompletedNCT00684138Phase 4
6Visual Outcomes of Subjects Bilaterally Implanted With ReSTOR Aspheric +4 vs. Tecnis or Acri.LISACompletedNCT00721253Phase 4
7Cognitive and Cerebral Blood Flow Effects of Vitamin CCompletedNCT01055418Phase 4
8Clinical Study to Evaluate the Visual Performance of Three Multifocal IOLsCompletedNCT02990689Phase 4
9Presbyopia-Correcting Intraocular Lenses (IOLs)CompletedNCT00963560Phase 4
10A Study of EGb 761® (Tanakan®) in Dementia of Alzheimer Type Onset in Patients Suffering From Memory ComplaintsCompletedNCT00276510Phase 4
11Corticolimbic Degeneration and Treatment of DementiaCompletedNCT00768261Phase 4
12Convenience, Tolerability, and Safety of Change in the Administration of Rivastigmine From Capsules to a Transdermal Patch in Patients With Mild to Moderate Alzheimer's DiseaseCompletedNCT00549601Phase 4
13Efficacy and Safety of Memantine Hydrochloride in Enhancing the Cognitive Abilities of Young Adults With Down SyndromeCompletedNCT01112683Phase 4
14Comparison of Outcomes With Multifocal Intraocular LensesRecruitingNCT02678962Phase 4
15Insulin Resistance and Mild Cognitive Impairment (IRMCI) StudyRecruitingNCT02409238Phase 4
16Behavioral Expressions in Alzheimer's DiseaseRecruitingNCT02719834Phase 4
17Visual Function With Contralateral AcrySof® ReSTOR® Aspheric SN6AD1 and SN6AD3TerminatedNCT00710905Phase 4
18Cerebrolysin Compared to Donepezil in Patients With Mild to Moderate Dementia of Alzheimer's Type (DAT)WithdrawnNCT01822951Phase 4
19Donepezil Treatment of Psychotic Symptoms in Dementia PatientsUnknown statusNCT00190021Phase 3
20Evaluating the Effects of Music Interventions on Hospitalised People With DementiaUnknown statusNCT00448318Phase 2, Phase 3
21Lidocaine Infusion for Major Abdominal Pediatric SurgeryCompletedNCT01387568Phase 3
22Efficacy Study of MPC-7869 to Treat Patients With Alzheimer'sCompletedNCT00105547Phase 3
23Rosiglitazone (Extended Release Tablets) As Adjunctive Therapy In Subjects With Mild To Moderate Alzheimer's DiseaseCompletedNCT00348140Phase 3
24An Efficacy and Safety Study of INM-176 for the Treatment of Patients With Alzheimer Type DementiaCompletedNCT01245530Phase 3
25Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of Alzheimer's TypeCompletedNCT01438060Phase 3
26A Study of the Safety and Efficacy of Memantine in Moderate to Severe Alzheimer's DiseaseCompletedNCT00322153Phase 3
27Study of Xaliproden (SR57746A) in Patients With Mild-to-Moderate Dementia of the Alzheimer's TypeCompletedNCT00104013Phase 3
2818-Month Study of the Efficacy of Xaliproden (SR57746A) in Patients With Mild-to-Moderate Dementia of the Alzheimer's TypeCompletedNCT00103649Phase 3
29Study of Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of the Alzheimer's TypeCompletedNCT00041678Phase 3
30Study of Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of the Alzheimer's TypeCompletedNCT00036114Phase 3
31An Efficacy and Safety Study of Galantamine for the Treatment of Patients With Alzheimer's DiseaseCompletedNCT00814801Phase 3
32The Safety and Efficacy of Neramexane in Patients With Moderate to Severe Alzheimer's DiseaseCompletedNCT00090116Phase 3
33Efficacy Assessment of Three Non Pharmacological Therapies in Alzheimer's DiseaseCompletedNCT00646269Phase 3
34Discontinuation of Cholinesterase Inhibitors for the Treatment of Severe Alzheimer's DiseaseCompletedNCT02035982Phase 3
35A 24-weeks, Multi-center, Randomized, Double-blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of Donepezil Hydrochloride in Chinese Subjects With Severe Alzheimer's DiseaseCompletedNCT01404169Phase 3
36Compare the Efficacy and Safety of Donepezil Hydrochloride 23 mg Treatment With Continuation of Donepezil Hydrochloride 10 mg Treatment in Japanese Subjects With Severe Alzheimer's DiseaseCompletedNCT01539031Phase 3
37Efficacy and Safety of the Rivastigmine Transdermal Patch in Patients With Probable Alzheimer's DiseaseCompletedNCT00099242Phase 3
38Safety and Efficacy of High Dose, Rapid Titration Galantamine in Patients With Alzheimer's DiseaseCompletedNCT00338117Phase 3
39Rosiglitazone (Extended Release Tablets) As Monotherapy In Subjects With Mild To Moderate Alzheimer's DiseaseCompletedNCT00428090Phase 3
40A Phase 3 Study Evaluating Safety and Effectiveness of Immune Globulin Intravenous (IGIV 10%) for the Treatment of Mild-to-Moderate Alzheimer´s DiseaseCompletedNCT00818662Phase 3
41Memantine and Validation of a New Alzheimer's Disease ScaleCompletedNCT00804271Phase 3
42Project COPE:Managing Dementia at HomeCompletedNCT00259454Phase 3
43Oculomotor Testing in the Differential Diagnosis of DementiaCompletedNCT01577394Phase 3
44Project ACT: Advancing Caregiving TechniquesCompletedNCT00259480Phase 3
45Efficacy and Safety of Aricept in the Treatment of Severe Alzheimer's DiseaseCompletedNCT00096473Phase 3
46Open Label Pilot Study of the Effects of Memantine on FDG-PET in Frontotemporal DementiaCompletedNCT00594737Phase 3
47Aripiprazole for the Treatment of Patients With Agitation Associated With Dementia of the Alzheimer's TypeRecruitingNCT02168920Phase 3
48Efficacy, Safety and Tolerability of AVP-786 (Deuterated [d6]-Dextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's TypeRecruitingNCT02442765Phase 3
49Efficacy, Safety, and Tolerability of AVP-786 (Deuterated [d6]-Dextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's TypeRecruitingNCT02442778Phase 3
50Long Term, Extension Study of the Safety and Efficacy of AVP-786 (Deuterated [d6] Dextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's TypeRecruitingNCT02446132Phase 3

Search NIH Clinical Center for Alzheimer Disease, Type 3

Genetic Tests for Alzheimer Disease, Type 3

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Genetic tests related to Alzheimer Disease, Type 3:

id Genetic test Affiliating Genes
1 Alzheimer Disease, Type 327
2 Alzheimer Disease, Familial, 3, with Spastic Paraparesis and Apraxia27
3 Alzheimer Disease Type 324 PSEN1

Anatomical Context for Alzheimer Disease, Type 3

About this section

MalaCards organs/tissues related to Alzheimer Disease, Type 3:

36
Brain, Testes, Breast, Eye, Bone

Publications for Alzheimer Disease, Type 3

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Variations for Alzheimer Disease, Type 3

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UniProtKB/Swiss-Prot genetic disease variations for Alzheimer Disease, Type 3:

70 (show all 73)
id Symbol AA change Variation ID SNP ID
1PSEN1p.Val82LeuVAR_006414rs63749967
2PSEN1p.Val96PheVAR_006415rs63750601
3PSEN1p.Tyr115CysVAR_006416rs63750450
4PSEN1p.Tyr115HisVAR_006417
5PSEN1p.Glu120AspVAR_006418rs63751272
6PSEN1p.Glu120LysVAR_006419rs63750800
7PSEN1p.Met139IleVAR_006420rs63750522
8PSEN1p.Met139ThrVAR_006421rs63751106
9PSEN1p.Met139ValVAR_006422rs63751037
10PSEN1p.Ile143PheVAR_006423rs63750322
11PSEN1p.Ile143ThrVAR_006424rs63750004
12PSEN1p.Met146LeuVAR_006426rs63750306
13PSEN1p.Met146ValVAR_006427rs63750306
14PSEN1p.His163ArgVAR_006428rs63750590
15PSEN1p.His163TyrVAR_006429rs63749885
16PSEN1p.Ser169LeuVAR_006430rs63751210
17PSEN1p.Ser169ProVAR_006431rs63750418
18PSEN1p.Leu171ProVAR_006432rs63750963
19PSEN1p.Gly209ValVAR_006433rs63750053
20PSEN1p.Ile213ThrVAR_006434rs63751309
21PSEN1p.Ala231ThrVAR_006435rs63749836
22PSEN1p.Ala231ValVAR_006436rs63750799
23PSEN1p.Met233ThrVAR_006437rs63751024
24PSEN1p.Leu235ProVAR_006438rs63749835
25PSEN1p.Ala246GluVAR_006439rs63750526
26PSEN1p.Leu250SerVAR_006440rs63751163
27PSEN1p.Ala260ValVAR_006441rs63751420
28PSEN1p.Leu262PheVAR_006442rs63750248
29PSEN1p.Cys263ArgVAR_006443rs63750543
30PSEN1p.Pro264LeuVAR_006444rs63750301
31PSEN1p.Pro267SerVAR_006445rs63751229
32PSEN1p.Pro267ThrVAR_006446
33PSEN1p.Arg269GlyVAR_006447rs63751019
34PSEN1p.Arg269HisVAR_006448rs63750900
35PSEN1p.Arg278ThrVAR_006449rs63749891
36PSEN1p.Glu280AlaVAR_006450rs63750231
37PSEN1p.Glu280GlyVAR_006451rs63750231
38PSEN1p.Ala285ValVAR_006452rs63751139
39PSEN1p.Leu286ValVAR_006453rs63751235
40PSEN1p.Gly378GluVAR_006455
41PSEN1p.Gly384AlaVAR_006456rs63750646
42PSEN1p.Leu392ValVAR_006457rs63751416
43PSEN1p.Cys410TyrVAR_006458rs661
44PSEN1p.Ala426ProVAR_006459rs63751223
45PSEN1p.Pro436GlnVAR_006460rs28930977
46PSEN1p.Pro436SerVAR_008141rs63749925
47PSEN1p.Phe105LeuVAR_009208rs63750321
48PSEN1p.Pro117LeuVAR_009209rs63749805
49PSEN1p.Gly209ArgVAR_009210rs63749880
50PSEN1p.Met233LeuVAR_009211rs63751287
51PSEN1p.Leu282ArgVAR_009212rs63750050
52PSEN1p.Ala409ThrVAR_009213rs63750227
53PSEN1p.Thr116AsnVAR_010120
54PSEN1p.Asn135AspVAR_010121rs63750353
55PSEN1p.Met139LysVAR_010122
56PSEN1p.Thr147IleVAR_010123rs63750907
57PSEN1p.Trp165CysVAR_010124rs63751484
58PSEN1p.Leu173TrpVAR_010125rs63750299
59PSEN1p.Leu219ProVAR_010126rs63750761
60PSEN1p.Ser289CysVAR_010127
61PSEN1p.Ser390IleVAR_010128rs63750883
62PSEN1p.Asn405SerVAR_010129rs63751254
63PSEN1p.Cys92SerVAR_016214rs63751141
64PSEN1p.Leu166ProVAR_016216rs63750265
65PSEN1p.Leu174MetVAR_016217rs63751144
66PSEN1p.Gly206AlaVAR_016218rs63750082
67PSEN1p.Gly266SerVAR_016219rs121917807
68PSEN1p.Leu271ValVAR_016220rs63750886
69PSEN1p.Ala431GluVAR_025605rs63750083
70PSEN1p.Leu262ValVAR_070025
71PSEN1p.Ile83ThrVAR_075261
72PSEN1p.Ile408ThrVAR_075277
73PSEN1p.Leu435PheVAR_075280rs63750001

Clinvar genetic disease variations for Alzheimer Disease, Type 3:

5 (show all 34)
id Gene Variation Type Significance SNP ID Assembly Location
1PSEN1NM_000021.3(PSEN1): c.436A> C (p.Met146Leu)SNVPathogenicrs63750306GRCh37Chr 14, 73640371: 73640371
2PSEN1NM_000021.3(PSEN1): c.488A> G (p.His163Arg)SNVPathogenicrs63750590GRCh37Chr 14, 73653568: 73653568
3PSEN1NM_000021.3(PSEN1): c.737C> A (p.Ala246Glu)SNVPathogenicrs63750526GRCh37Chr 14, 73659540: 73659540
4PSEN1NM_000021.3(PSEN1): c.856C> G (p.Leu286Val)SNVPathogenicrs63751235GRCh37Chr 14, 73664825: 73664825
5PSEN1NM_000021.3(PSEN1): c.1229G> A (p.Cys410Tyr)SNVPathogenicrs661GRCh37Chr 14, 73683933: 73683933
6PSEN1NM_000021.3(PSEN1): c.415A> G (p.Met139Val)SNVPathogenicrs63751037GRCh37Chr 14, 73640350: 73640350
7PSEN1NM_000021.3(PSEN1): c.436A> G (p.Met146Val)SNVPathogenicrs63750306GRCh37Chr 14, 73640371: 73640371
8PSEN1NM_000021.3(PSEN1): c.487C> T (p.His163Tyr)SNVPathogenicrs63749885GRCh37Chr 14, 73653567: 73653567
9PSEN1NM_000021.3(PSEN1): c.839A> C (p.Glu280Ala)SNVPathogenicrs63750231GRCh37Chr 14, 73664808: 73664808
10PSEN1NM_000021.3(PSEN1): c.839A> G (p.Glu280Gly)SNVPathogenicrs63750231GRCh37Chr 14, 73664808: 73664808
11PSEN1NM_000021.3(PSEN1): c.799C> T (p.Pro267Ser)SNVPathogenicrs63751229GRCh37Chr 14, 73664768: 73664768
12PSEN1PSEN1, IVS8AS, G-T, -1, EX9DELdeletionPathogenicChr na, -1: -1
13PSEN1NM_000021.3(PSEN1): c.360A> T (p.Glu120Asp)SNVPathogenicrs63751272GRCh37Chr 14, 73640295: 73640295
14PSEN1NM_000021.3(PSEN1): c.1276G> C (p.Ala426Pro)SNVPathogenicrs63751223GRCh37Chr 14, 73685869: 73685869
15PSEN1NM_000021.3(PSEN1): c.438G> A (p.Met146Ile)SNVPathogenicrs63750391GRCh37Chr 14, 73640373: 73640373
16PSEN1NM_000021.3(PSEN1): c.749T> C (p.Leu250Ser)SNVPathogenicrs63751163GRCh37Chr 14, 73659552: 73659552
17PSEN1PSEN1, IVS4DS, 1-BP DEL, GdeletionPathogenicChr na, -1: -1
18PSEN1NM_000021.3(PSEN1): c.1300_1301delGCinsTG (p.Ala434Cys)indelPathogenicrs281875357GRCh37Chr 14, 73685893: 73685894
19PSEN1NM_000021.3(PSEN1): c.275G> C (p.Cys92Ser)SNVPathogenicrs63751141GRCh37Chr 14, 73637692: 73637692
20PSEN1NM_000021.3(PSEN1): c.617G> C (p.Gly206Ala)SNVPathogenicrs63750082GRCh37Chr 14, 73659420: 73659420
21PSEN1NM_000021.3(PSEN1): c.338T> C (p.Leu113Pro)SNVPathogenicrs63751399GRCh37Chr 14, 73637755: 73637755
22PSEN1NM_000021.3(PSEN1): c.497T> C (p.Leu166Pro)SNVPathogenicrs63750265GRCh37Chr 14, 73653577: 73653577
23PSEN1NM_000021.3(PSEN1): c.520C> A (p.Leu174Met)SNVPathogenicrs63751144GRCh37Chr 14, 73653600: 73653600
24PSEN1NM_000021.3(PSEN1): c.548G> T (p.Gly183Val)SNVPathogenicrs63751068GRCh37Chr 14, 73653628: 73653628
25PSEN1NM_000021.3(PSEN1): c.1307C> A (p.Pro436Gln)SNVPathogenicrs121917808GRCh37Chr 14, 73685900: 73685900
26PSEN1NM_000021.3(PSEN1): c.833G> T (p.Arg278Ile)SNVPathogenicrs63749891GRCh37Chr 14, 73664802: 73664802
27PSEN1NM_000021.3(PSEN1): c.1292C> A (p.Ala431Glu)SNVPathogenicrs63750083GRCh37Chr 14, 73685885: 73685885
28PSEN1NM_000021.3(PSEN1): c.236C> T (p.Ala79Val)SNVPathogenicrs63749824GRCh37Chr 14, 73637653: 73637653
29PSEN1NM_000021.3(PSEN1): c.509C> T (p.Ser170Phe)SNVPathogenicrs63750577GRCh37Chr 14, 73653589: 73653589
30PSEN1NM_000021.3(PSEN1): c.1175T> C (p.Leu392Pro)SNVPathogenicrs63750218GRCh37Chr 14, 73683879: 73683879
31PSEN1NM_000021.3(PSEN1): c.265G> T (p.Val89Leu)SNVPathogenicrs63750815GRCh37Chr 14, 73637682: 73637682
32PSEN1NM_000021.3(PSEN1): c.697A> G (p.Met233Val)SNVPathogenicrs63751287GRCh37Chr 14, 73659500: 73659500
33PSEN1NM_000021.3(PSEN1): c.767A> C (p.Tyr256Ser)SNVPathogenicrs63751320GRCh37Chr 14, 73659570: 73659570
34PSEN1NM_000021.3(PSEN1): c.1141C> G (p.Leu381Val)SNVPathogenicrs63750687GRCh37Chr 14, 73683845: 73683845

Expression for genes affiliated with Alzheimer Disease, Type 3

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Search GEO for disease gene expression data for Alzheimer Disease, Type 3.

Pathways for genes affiliated with Alzheimer Disease, Type 3

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Pathways related to Alzheimer Disease, Type 3 according to GeneCards Suite gene sharing:

(show all 11)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.1PSEN1, PSEN2
29.1PSEN1, PSEN2
3
Show member pathways
9.1PSEN1, PSEN2
4
Show member pathways
9.1PSEN1, PSEN2
59.1PSEN1, PSEN2
6
Show member pathways
9.1PSEN1, PSEN2
79.1PSEN1, PSEN2
89.1PSEN1, PSEN2
99.1PSEN1, PSEN2
109.1PSEN1, PSEN2
119.1PSEN1, PSEN2

GO Terms for genes affiliated with Alzheimer Disease, Type 3

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Cellular components related to Alzheimer Disease, Type 3 according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1centrosomeGO:00058139.9PSEN1, PSEN2
2Golgi membraneGO:00001399.8PSEN1, PSEN2
3kinetochoreGO:00007769.8PSEN1, PSEN2
4neuronal cell bodyGO:00430259.8PSEN1, PSEN2
5protein complexGO:00432349.1PSEN1, PSEN2

Biological processes related to Alzheimer Disease, Type 3 according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1amyloid precursor protein catabolic processGO:00429879.9PSEN1, PSEN2
2beta-amyloid metabolic processGO:00504359.9PSEN1, PSEN2
3intracellular signal transductionGO:00355569.8PSEN1, PSEN2
4membrane protein ectodomain proteolysisGO:00065099.8PSEN1, PSEN2
5negative regulation of apoptotic processGO:00430669.8PSEN1, PSEN2
6Notch receptor processingGO:00072209.8PSEN1, PSEN2
7Notch signaling pathwayGO:00072199.8PSEN1, PSEN2
8positive regulation of apoptotic processGO:00430659.7PSEN1, PSEN2
9positive regulation of catalytic activityGO:00430859.6PSEN1, PSEN2
10protein processingGO:00164859.1PSEN1, PSEN2

Molecular functions related to Alzheimer Disease, Type 3 according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1aspartic-type endopeptidase activityGO:00041909.6PSEN1, PSEN2
2endopeptidase activityGO:00041759.1PSEN1, PSEN2

Sources for Alzheimer Disease, Type 3

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet