Alzheimer Disease, Type 3, with Spastic Paraparesis and Apraxia malady

MalaCards: Alzheimer Disease, Type 3, with Spastic Paraparesis and Apraxia, also known as alzheimer's disease, is related to alzheimer disease, type 3, with spastic paraparesis and unusual plaques. An important gene associated with Alzheimer Disease, Type 3, with Spastic Paraparesis and Apraxia is PSEN1 (presenilin 1). The drugs divalproex and galantamine hydrobromide have been mentioned in the context of this disorder.

OMIM: 607822

alzheimer disease, type 3, with spastic paraparesis and apraxia 33 alzheimer's disease 43

Diseases related to alzheimer disease, type 3, with spastic paraparesis and apraxia by text searches and GeneDecks gene sharing:

id	Related Disease	Score	Top Affiliating Genes
1	alzheimer disease, type 3, with spastic paraparesis and unusual plaques	6.2

Clinical features from OMIM: 607822

Approved drugs:

Drug clinical trials:

Inferred drug relations via UMLS/NDF-RT:

^43 28 divalproex, divalproex sodium, donepezil, donepezil hydrochloride, galantamine, galantamine hydrobromide, rivastigmine, rivastigmine tartrate, selegiline, selegiline hydrochloride, tacrine, tacrine hydrochloride, valproate sodium, valproic acid

Genes related to alzheimer disease, type 3, with spastic paraparesis and apraxia according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	PSEN1	presenilin 1	11.1	Disorders