MCID: ALZ025

Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual Plaques malady

Summaries for Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual...

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33OMIM, 22MalaCards
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MalaCards: Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual Plaques, also known as alzheimer's disease, is related to alzheimer disease familial and frontotemporal dementia. An important gene associated with Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual Plaques is PSEN1 (presenilin 1). The drugs divalproex and galantamine hydrobromide have been mentioned in the context of this disorder.

OMIM: 607822

Aliases & Descriptions for Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual...

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33OMIM, 43UMLS
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alzheimer disease, type 3, with spastic paraparesis and unusual plaques 33
alzheimer's disease 43

Related Diseases for Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual...

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13GeneCards, 14GeneDecks
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Diseases related to alzheimer disease, type 3, with spastic paraparesis and unusual plaques by text searches and GeneDecks gene sharing:

(show top 50)    (show all 67)
idRelated DiseaseScoreTop Affiliating Genes
1alzheimer disease familial9.7
2frontotemporal dementia9.7
3early-onset familial alzheimer disease9.5
4tauopathy9.3
5lewy body dementia9.2
6memory impairment8.8
7neuroblastoma8.8
8cerebral hemorrhage8.6
9multiple system atrophy8.0
10neurologic diseases8.0
11was-related disorders8.0
12alzheimer disease type 38.0
13corticobasal degeneration8.0
14huntington's disease8.0
15alzheimer's disease without neurofibrillary tangles7.7
16hereditary cerebral hemorrhage with amyloidosis7.7
17normal pressure hydrocephalus7.7
18twinning7.7
19gliosis7.1
20hemochromatosis7.1
21hydrocephalus7.1
22logopenic progressive aphasia7.1
23rem sleep behavior disorder7.1
24spinocerebellar ataxia7.1
25alzheimer disease type 27.1
26ataxia7.1
27convulsions6.2
28prostatitis6.2
29alzheimer disease risk factor (apoe genotype)6.2
30cr1 deficiency6.2
31head injury6.2
32pertussis6.2
33alzheimer disease, pathogenesis, association with6.2
34cerebral atherosclerosis6.2
35hereditary diffuse leukoencephalopathy with spheroids6.2
36retinol binding protein6.2
37alzheimer disease, type 3, with spastic paraparesis and apraxia6.2
38cerebral atrophy6.2
39herpes simplex6.2
40subcortical arteriosclerotic encephalopathy6.2
41aphasia6.2
42hyperlipoproteinemia6.2
43substance dependence6.2
44apraxia6.2
45lymphoblastic leukemia6.2
46scrapie6.2
47degenerative nerve diseases6.2
48sjogren's syndrome6.2
49dementia - subcortical6.2
50meningoencephalitis6.2

Graphical network of the top 20 diseases related to alzheimer disease, type 3, with spastic paraparesis and unusual plaques:



Graphical network of diseases related to alzheimer disease, type 3, with spastic paraparesis and unusual plaques

Clinical Features for Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual...

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33OMIM
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Clinical features from OMIM: 607822

Drugs & Therapeutics for Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual...

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4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT
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Approved drugs:

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Drug clinical trials:

Search ClinicalTrials for alzheimer disease, type 3, with spastic paraparesis and unusual plaques

Search NIH Clinical Center for alzheimer disease, type 3, with spastic paraparesis and unusual plaques

Search CenterWatch for alzheimer disease, type 3, with spastic paraparesis and unusual plaques

Inferred drug relations via UMLS/NDF-RT:

43 28 divalproex, divalproex sodium, donepezil, donepezil hydrochloride, galantamine, galantamine hydrobromide, rivastigmine, rivastigmine tartrate, selegiline, selegiline hydrochloride, tacrine, tacrine hydrochloride, valproate sodium, valproic acid

Genetic Tests for Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual...

Anatomical Context for Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual...

Phenotypes for genes affiliated with Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual...

Publications for genes affiliated with Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual...

Expression for genes affiliated with Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual...

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1BioGPS
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Expression patterns in normal tissues for genes affiliated with Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual Plaques

Pathways for genes affiliated with Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual...

Compounds for genes affiliated with Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual...

GO Terms for genes affiliated with Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual...

Sources for Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual...

2CDC
11FMA
18HMDB
19ICD9CM
20KEGG
24MeSH
25MGI
27NCIt
28NDF-RT
31NINDS
32Novoseek
33OMIM
35PubMed
36QIAGEN
43UMLS