MCID: AMR003
MIFTS: 35

Amaurosis Fugax malady

Rare diseases, Neuronal diseases categories

Aliases & Classifications for Amaurosis Fugax

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Aliases & Descriptions for Amaurosis Fugax:

Name: Amaurosis Fugax 42
 
Transient Monocular Blindness 42


Classifications:



External Ids:

ICD1025 G45.3

Summaries for Amaurosis Fugax

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Wikipedia:64 Amaurosis fugax (Latin fugax meaning fleeting, Greek amaurosis meaning darkening, dark, or obscure) is a... more...

MalaCards based summary: Amaurosis Fugax, also known as transient monocular blindness, is related to retinal artery occlusion and sneddon syndrome. An important gene associated with Amaurosis Fugax is MMP8 (matrix metallopeptidase 8 (neutrophil collagenase)), and among its related pathways are Cell adhesion ECM remodeling and Formation of Fibrin Clot (Clotting Cascade). The compounds kaolin and cacl2 have been mentioned in the context of this disorder. Affiliated tissues include eye, endothelial and prostate.

Related Diseases for Amaurosis Fugax

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Graphical network of the top 20 diseases related to Amaurosis Fugax:



Diseases related to amaurosis fugax

Symptoms for Amaurosis Fugax

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Drugs & Therapeutics for Amaurosis Fugax

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Drug clinical trials:

Search ClinicalTrials for Amaurosis Fugax

Search NIH Clinical Center for Amaurosis Fugax

Genetic Tests for Amaurosis Fugax

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Anatomical Context for Amaurosis Fugax

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MalaCards organs/tissues related to Amaurosis Fugax:

31
Eye, Endothelial, Prostate, Pituitary

Animal Models for Amaurosis Fugax or affiliated genes

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Publications for Amaurosis Fugax

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Articles related to Amaurosis Fugax:

(show top 50)    (show all 182)
idTitleAuthorsYear
1
Recurrent amaurosis fugax and hemichorea: limb-shaking TIA. (25617405)
2015
2
Increased intraocular pressure after vitreoretinal surgery as a cause of ipsilateral amaurosis fugax upon rising to a standing position. (25613128)
2015
3
Amaurosis fugax caused by neurocysticercosis. (24632665)
2014
4
Cervical rib resulting in amaurosis fugax and stroke. (24035686)
2013
5
Light-induced amaurosis fugax due to severe distal internal carotid artery stenosis: in view of managing ocular ischemic syndrome. (23568216)
2013
6
Detection of unstable carotid plaque by tissue Doppler imaging and contrast-enhanced ultrasound in a patient with recurrent amaurosis fugax. (23365782)
2013
7
Does amaurosis fugax after retrobulbar injection need any treatment? (23595404)
2013
8
Patent foramen ovale presenting with amaurosis fugax. (23472288)
2012
9
Sleep-induced amaurosis fugax. (21723066)
2011
10
Amaurosis fugax is in the first place, during attack, medical emergency for ophthalmologist's practice. (21302720)
2010
11
Diagnosing amaurosis fugax with emergency ultrasound. (20015107)
2010
12
Retinal artery embolization from a calcified bicuspid aortic valve causing amaurosis fugax. (20934672)
2010
13
Novel mouse model of monocular amaurosis fugax. (17975099)
2007
14
Amaurosis fugax caused by heritable thrombophilia-hypofibrinolysis in cases without carotid atherosclerosis: thromboprophylaxis prevents subsequent transient monocular partial blindness. (17456620)
2007
15
Exercise-induced vasospastic amaurosis fugax. (11831932)
2002
16
Wegener's granulomatosis presenting with amaurosis fugax. (12194103)
2002
17
Light-induced amaurosis fugax. (11336956)
2001
18
Amaurosis fugax and stenosis of the ophthalmic artery--a case report. (11668383)
2001
19
Vertigo and amaurosis fugax secondary to Takayasu's arteritis. (11459913)
2001
20
Clinical and pathophysiological features of amaurosis fugax in Japanese stroke patients. (10732827)
2000
21
The prognosis of amaurosis fugax and hemispheric transient ischemic attacks. (10396657)
1999
22
Takayasu arteritis presenting as amaurosis fugax in a man. (9517701)
1998
23
Amaurosis fugax as a symptom of carotid artery stenosis. Its relationship with ulcerated plaque. (8120072)
1994
24
Jaw claudication and amaurosis fugax secondary to atheromatous disease of the carotid arteries. (8019808)
1994
25
Amaurosis fugax: prognosis and the role of acetylsalicylic acid. (7922849)
1994
26
Brief report: treatment of vasospastic amaurosis fugax with calcium-channel blockers. (8326973)
1993
27
Amaurosis fugax in young adults. (8343483)
1993
28
Amaurosis fugax in young people. (1477040)
1992
29
Recurrent attacks of amaurosis fugax treated with calcium channel blocker. (1952830)
1991
30
Carotid endarterectomy and its alternatives in managing amaurosis fugax. (1743894)
1991
31
Amaurosis fugax in a young woman. (1972478)
1990
32
Amaurosis fugax and antiphospholipid antibodies. (1975351)
1990
33
Dynamic amaurosis fugax secondary to compression of vertebral artery. (3044227)
1988
34
Amaurosis fugax in teenagers. A migraine variant. (3344721)
1988
35
Amaurosis fugax in a patient with systemic lupus erythematosus and antiphospholipid antibodies. (3427847)
1987
36
Amaurosis fugax and thrombocythemia. (3683889)
1987
37
Postprandial transient painful amaurosis fugax. (3746361)
1986
38
Amaurosis fugax and retinal vasculitis associated with methamphetamine inhalation. (2934418)
1985
39
Reversible monocular cataract simulating amaurosis fugax. (4037603)
1985
40
Peripheral arterial occlusion and amaurosis fugax as the first manifestation of polycythemia vera. A case report. (6697006)
1984
41
Amaurosis fugax for a long duration. (6222083)
1983
42
Amaurosis fugax. (6812749)
1982
43
Demonstration of pathological circulating endothelial cells in patients with amaurosis fugax. (6946628)
1980
44
Peripapillary staphyloma and amaurosis fugax. (900730)
1977
45
Evidence of silent cerebral embolism in patients with amaurosis fugax. (915508)
1977
46
Effect of aspirin in amaurosis fugax. (4108964)
1972
47
Carotid artery surgery and intermittent monocular blindness (amaurosis fugax). (4501615)
1972
48
Effect of aspirin in amaurosis fugax. (4106235)
1971
49
The natural history of monocular amaurosis fugax. (5782087)
1969
50
Amaurosis fugax: a specific type of transient loss of vision. (13398129)
1957

Variations for Amaurosis Fugax

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Expression for genes affiliated with Amaurosis Fugax

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Search GEO for disease gene expression data for Amaurosis Fugax.

Pathways for genes affiliated with Amaurosis Fugax

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Pathways related to Amaurosis Fugax according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Metalloproteases in connective tissue degradation
9.2MMP8, SERPINE1
2
Show member pathways
9.1F5, SERPINE1
3
Show member pathways
Complement Activation, Classical Pathway36
Complement and Coagulation Cascades36
9.1F5, SERPINE1
4
Show member pathways
9.1F5, SERPINE1
5
Show member pathways
thioredoxin pathway36
9.0SERPINE1, MTHFR

Compounds for genes affiliated with Amaurosis Fugax

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Compounds related to Amaurosis Fugax according to GeneCards Suite gene sharing:

(show top 50)    (show all 72)
idCompoundScoreTop Affiliating Genes
1kaolin449.8F5, APOH
2cacl2449.8F5, MMP8
3coumarins449.8APOH, F5
45-methyltetrahydrofolate44 1110.7F5, MTHFR
5cardiolipin44 1110.7F5, APOH
6cystathionine449.7F5, MTHFR
7phosphatidylethanolamine44 1110.6F5, APOH
8vitamin b6449.6MTHFR, F5
9batroxobin449.5F5, SERPINE1
10ancrod449.5F5, SERPINE1
1111-dehydrothromboxane b2449.5APOH, SERPINE1
12tibolone449.5F5, SERPINE1
13cyproteroneacetate449.5SERPINE1, F5
14deoxyribonucleic acid449.4F5, APOH
15desmopressin44 60 28 1112.4F5, SERPINE1
16malondialdehyde449.4APOH, F5
178-isoprostane449.4APOH, SERPINE1
18hirudin449.4F5, SERPINE1
19p00001449.3MTHFR, SERPINE1
20dextran sulfate449.3F5, APOH
21protamine449.3F5, SERPINE1
22warfarin44 50 24 1112.2MTHFR, APOH, F5
23mycophenolate mofetil44 50 1111.2SERPINE1, F5
24vitamin b12449.2APOH, MTHFR, F5
25lactate449.2APOH, MMP8, F5
26raloxifene44 50 28 1112.2SERPINE1, F5
27folate449.2APOH, MTHFR, F5
28kininogen449.0SERPINE1, APOH, F5
29pge1449.0SERPINE1, F5, APOH
30betacarotene449.0MTHFR, APOH
31endotoxin449.0SERPINE1, F5, APOH
32prostacyclin449.0APOH, SERPINE1, F5
33metformin44 50 1110.9F5, MTHFR, SERPINE1
34methotrexate50 44 1110.9APOH, SERPINE1, MTHFR
35p002448.8F5, MTHFR, APOH, MMP8
36aspartate448.7MTHFR, SERPINE1, F5
37progesterone44 28 60 24 1112.6SERPINE1, F5, MMP8, APOH
38vegf448.6F5, MMP8, SERPINE1, APOH
39nitric oxide44 24 1110.5F5, MMP8, APOH, SERPINE1
40uric acid44 249.4SERPINE1, F5, MTHFR, APOH
41homocysteine44 249.4APOH, F5, MTHFR, SERPINE1
42cyclophosphamide44 50 1110.4SERPINE1, MTHFR, F5, APOH
43aspirin44 50 28 2411.4SERPINE1, F5, MTHFR, APOH
44creatinine448.4MTHFR, F5, APOH, SERPINE1
45heparin44 28 24 1111.4F5, MTHFR, SERPINE1, APOH
46retinoic acid44 249.4MTHFR, SERPINE1, F5, MMP8
47cholesterol44 28 24 1111.4F5, MTHFR, SERPINE1, APOH
48estrogen448.3MTHFR, F5, APOH, SERPINE1
49serine448.3F5, MTHFR, MMP8, SERPINE1
50fibrinogen448.0MTHFR, SERPINE1, MMP8, F5, APOH

GO Terms for genes affiliated with Amaurosis Fugax

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Cellular components related to Amaurosis Fugax according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular matrixGO:00310129.1SERPINE1, APOH
2platelet alpha granule lumenGO:00310938.8F5, SERPINE1
3extracellular spaceGO:00056158.1F5, MMP8, SERPINE1, APOH

Biological processes related to Amaurosis Fugax according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of fibrinolysisGO:00519189.2SERPINE1, APOH
2positive regulation of blood coagulationGO:00301949.1SERPINE1, APOH
3platelet degranulationGO:00025769.1F5, SERPINE1
4negative regulation of blood coagulationGO:00301959.0APOH, SERPINE1
5blood circulationGO:00080159.0F5, MTHFR

Molecular functions related to Amaurosis Fugax according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1serine-type endopeptidase activityGO:00042529.5F5, MMP8

Sources for Amaurosis Fugax

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet