MCID: AML001
MIFTS: 40

Amelanotic Melanoma malady

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Amelanotic Melanoma

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Aliases & Descriptions for Amelanotic Melanoma:

Name: Amelanotic Melanoma 10 12
Melanoma, Amelanotic 36 65
 
Amelanotic Skin Melanoma 65
Melanoma Amelanotic 47

Classifications:



External Ids:

Disease Ontology10 DOID:4359
MeSH36 D018328
SNOMED-CT59 70594002
NCIt42 C3802
UMLS65 C0206735

Summaries for Amelanotic Melanoma

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Wikipedia:68 Amelanotic melanoma is a type of skin cancer in which the cells do not make melanin. They can be... more...

MalaCards based summary: Amelanotic Melanoma, also known as melanoma, amelanotic, is related to skin amelanotic melanoma and melanoma. An important gene associated with Amelanotic Melanoma is TYR (Tyrosinase), and among its related pathways are Tyrosine metabolism and Basal cell carcinoma. The drugs cisplatin and cisplatin pwdr have been mentioned in the context of this disorder. Affiliated tissues include skin, breast and lung, and related mouse phenotypes are vision/eye and renal/urinary system.

Related Diseases for Amelanotic Melanoma

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Diseases related to Amelanotic Melanoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 67)
idRelated DiseaseScoreTop Affiliating Genes
1skin amelanotic melanoma12.1
2melanoma11.0
3skin benign neoplasm10.5KIT, TYR
4sweat gland cancer10.5KIT, TYR
5malignant fibroxanthoma10.5KIT, TYR
6gallbladder leiomyosarcoma10.5KIT, TYR
7hepatic osteogenic sarcoma10.5BRAF, KIT
8sublingual gland adenoid cystic carcinoma10.4BRAF, KIT
9connective tissue benign neoplasm10.4KIT, TYR
10mast cell neoplasm10.3CTSG, KIT
11diffuse cutaneous mastocytosis10.3CTSG, KIT
12albinism10.2
13chediak-higashi syndrome10.2CTSG, TYR
14oculocutaneous albinism10.2
15lipoadenoma10.1DRD2, TYRP1
16choroiditis10.1
17adenocarcinoma10.1
18pyogenic granuloma10.1
19dyslexia10.1S100B, TYR
20benign mesothelioma10.1KIT, S100B
21intrahepatic gall duct cancer10.0TYR, TYRP1
22melanoma metastasis10.0
23endotheliitis10.0
24ocular albinism10.0TYR, TYRP1
25vesicoureteral reflux10.0KIT, S100B
26intracranial cavernous angioma10.0KIT, TYR, TYRP1
27cellular schwannoma9.9KIT, S100B
28factor v leiden thrombophilia9.9TYR, TYRP1
29corneal intraepithelial dyskeratosis and ectodermal dysplasia9.9DCT, TYR, TYRP1
30ulcer of lower limbs9.9DRD2, S100B
31primary thrombocytopenia9.9BRAF, TYR
32brain ischemia9.9DRD2, S100B
33malaria9.9
34rothmund-thomson syndrome9.9
35burn scar9.9
36burns9.9
37diabetic foot ulcers9.9
38hepatitis9.9
39dysplastic nevus syndrome9.9
40sarcoma9.9
41plasmodium falciparum malaria9.9
42ocular melanoma9.9
43giant cell tumor9.9
44nodular hidradenoma9.9
45vaginitis9.9
46colon adenocarcinoma9.9
47ovarian cancer9.9
48cervicitis9.9
49papilloma9.9
50cystic teratoma9.9

Graphical network of the top 20 diseases related to Amelanotic Melanoma:



Diseases related to amelanotic melanoma

Symptoms for Amelanotic Melanoma

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Drugs & Therapeutics for Amelanotic Melanoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Amelanotic Melanoma

Inferred drug relations via UMLS65/NDF-RT43:


Cochrane evidence based reviews: melanoma, amelanotic

Genetic Tests for Amelanotic Melanoma

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Anatomical Context for Amelanotic Melanoma

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MalaCards organs/tissues related to Amelanotic Melanoma:

33
Skin, Breast, Lung, Colon, Endothelial, B cells, Prostate

Animal Models for Amelanotic Melanoma or affiliated genes

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MGI Mouse Phenotypes related to Amelanotic Melanoma:

38 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053919.0BRAF, DCT, KIT, TYR, TYRP1
2MP:00053678.6BRAF, DRD2, KIT, SLC4A1, TYR
3MP:00011868.4BRAF, DCT, DRD2, KIT, TYR, TYRP1
4MP:00053868.3BRAF, DRD2, KIT, S100B, TYR, TYRP1
5MP:00020068.0BRAF, CTSG, DRD2, KIT, TYR, TYRP1
6MP:00028737.8BRAF, CTSG, DRD2, KIT, S100B, TYR
7MP:00053877.6BRAF, CTSG, DRD2, KIT, SLC4A1, TYR
8MP:00107717.3BRAF, DCT, DRD2, KIT, S100B, SLC4A1
9MP:00107687.3BRAF, CTSG, DRD2, KIT, SLC4A1, TYR

Publications for Amelanotic Melanoma

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Articles related to Amelanotic Melanoma:

(show top 50)    (show all 239)
idTitleAuthorsYear
1
Polarized light dermoscopy to aid in the diagnosis of new pink lesions in an amelanotic melanoma survivor. (26568348)
2015
2
Comparative analysis of pathology and boronophenylalanine uptake in experimental orthotopic and heterotopic amelanotic melanoma. (24915302)
2014
3
Amelanotic melanoma mimicking cutaneous epitheliomas. (24629365)
2014
4
Amelanotic melanoma masquerading as a granular cell lesion. (23533832)
2013
5
Characteristics and survival of patients with invasive amelanotic melanoma in the USA. (23883947)
2013
6
Hyporeflective pagetoid cells: A new clue for amelanotic melanoma diagnosis by reflectance confocal microscopy. (24329036)
2013
7
Vaginal fistula in a patient with relapsed ovarian cancer and amelanotic melanoma. (22593454)
2012
8
Conjunctival amelanotic melanoma--a case report. (22220456)
2011
9
Cytoplasmic immunoreactivity for Ki67 in an invasive amelanotic melanoma--foe or faux pas? (21062343)
2011
10
In situ amelanotic melanoma of the nail unit mimicking lichen planus: report of 3 cases. (20404232)
2010
11
Amelanotic melanoma presenting as contact dermatitis. (20956099)
2010
12
Nodular amelanotic melanoma. (20445300)
2010
13
Malignant amelanotic melanoma of the pleura without primary skin lesion:an autopsy case report. (20035295)
2009
14
Massive cardiac invasion by amelanotic melanoma with obstructive clinical features. (18372490)
2008
15
The activity of caspases in spontaneous and camptothecin-induced death of melanotic and amelanotic melanoma cell. (17312383)
2007
16
Mitochondrial transmembrane potential in spontaneous and camptothecin-induced apoptosis of melanotic and amelanotic melanoma cells. (17203890)
2007
17
Spontaneous apoptosis of melanotic and amelanotic melanoma cells in different phases of cell cycle: relation to tumor growth. (16584089)
2006
18
Dermoscopy for "true" amelanotic melanoma: a clinical dermoscopic-pathologic case study. (16443072)
2006
19
Primary treatment of choroidal amelanotic melanoma with photodynamic therapy--comment. (16970777)
2006
20
Improvement of the tumor-suppressive effect of boron neutron capture therapy for amelanotic melanoma by intratumoral injection of the tyrosinase gene. (16585201)
2006
21
Immunophenotyping of amelanotic melanoma. A case report. (17053850)
2006
22
Polymorphous vascular patterns in dermoscopy as a sign of malignant skin tumors. A case of an amelanotic melanoma and a porocarcinoma. (15604548)
2005
23
The first description of sentinel node biopsy in a patient with amelanotic melanoma of the glans penis. (16314746)
2005
24
Amelanotic melanoma in a child with oculocutaneous albinism. (12825234)
2003
25
Duodenal metastatic amelanotic melanoma. (12838234)
2003
26
Progressive appearance of pigmentation in amelanotic melanoma lesions. (12100494)
2002
27
Complete remission of Bomirski Ab amelanotic melanoma in hamsters treated with the angiogenesis inhibitor TNP-470. (12458330)
2002
28
Tissue distribution and penetration of 5-ALA induced fluorescence in an amelanotic melanoma after topical application. (11299790)
2001
29
Subungual amelanotic melanoma. (10826092)
2000
30
Neurocutaneous melanosis presenting with intracranial amelanotic melanoma. (10219411)
1999
31
Irradiation of amelanotic melanoma cells with 532 nm high peak power pulsed laser radiation in the presence of the photothermal sensitizer Cu(II)-hematoporphyrin: a new approach to cell photoinactivation. (10378011)
1999
32
Enhanced melanogenesis induced by tyrosinase gene-transfer increases boron-uptake and killing effect of boron neutron capture therapy for amelanotic melanoma. (9877098)
1998
33
Tyrosinase, melan-A, and KBA62 as markers for the immunohistochemical identification of metastatic amelanotic melanomas on paraffin sections. (9720502)
1998
34
Photodynamic therapy with 5-aminolaevulinic acid-induced porphyrins of an amelanotic melanoma in vivo. (9301046)
1997
35
Visualization of uveal amelanotic melanoma with technetium-99m(V) dimercaptosuccinic acid. (9212896)
1997
36
Amelanotic melanoma and hypercalcaemia. (8958374)
1996
37
An epithelioid cell type of amelanotic melanoma of the pinna in a Fischer-344 rat: a case report. (8992617)
1996
38
Amelanotic melanoma. (7632069)
1995
39
Diagnostic ophthalmology. Amelanotic melanoma in an 8-year-old cat. (7585441)
1995
40
Analyses of mixed melanogenesis in tyrosinase cDNA-transfected human amelanotic melanoma cells. (8245515)
1993
41
Amelanotic melanoma presenting as inflammatory plaques. (1401291)
1992
42
The biphasic nature of a human amelanotic melanoma tumour line HT-18. (3151541)
1988
43
Ultrastructural aspects of melanization of hamster Ab amelanotic melanoma in primary cell culture. (2433873)
1986
44
Diagnostic electron microscopy for amelanotic melanoma: correlation of patient biopsy, soft agar assay, and xenograft. (6620008)
1983
45
Plasmodium falciparum strain-specific antibody blocks binding of infected erythrocytes to amelanotic melanoma cells. (6343885)
1983
46
An amelanotic melanoma transformed into melanotic melanoma with development of vitiligo. (7037894)
1981
47
Comparison of the antigenicity of melanotic and amelanotic melanoma cells after the release of surface glycoproteins by trypsin. (7192976)
1980
48
Junctions of endoplasmic reticulum and virus like intranuclear inclusions and virus like intranuclear inclusions in amelanotic melanoma metastatic to the jejunum. (7414714)
1980
49
Activity of some lysosomal hydrolases in the homogenates of transplantable melanotic and amelanotic melanoma in golden hamster (Mesocricetus auratus, Waterhouse). (686981)
1978
50
A clinicopathologic study of amelanotic melanoma. (5086000)
1972

Variations for Amelanotic Melanoma

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Expression for genes affiliated with Amelanotic Melanoma

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Search GEO for disease gene expression data for Amelanotic Melanoma.

Pathways for genes affiliated with Amelanotic Melanoma

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GO Terms for genes affiliated with Amelanotic Melanoma

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Biological processes related to Amelanotic Melanoma according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1myeloid progenitor cell differentiationGO:000231810.1BRAF, KIT
2thymus developmentGO:00485389.8BRAF, TYR
3somatic stem cell population maintenanceGO:00350199.7BRAF, KIT
4long-term synaptic potentiationGO:00602919.5BRAF, S100B
5intracellular signal transductionGO:00355569.3BRAF, DRD2, KIT
6visual learningGO:00085429.2DRD2, KIT
7pigmentationGO:00434738.8DCT, DRD2, KIT, TYRP1

Sources for Amelanotic Melanoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet