MCID: AML001
MIFTS: 39

Amelanotic Melanoma malady

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Amelanotic Melanoma

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Aliases & Descriptions for Amelanotic Melanoma:

Name: Amelanotic Melanoma 11 13
Melanoma, Amelanotic 38 67
 
Amelanotic Skin Melanoma 67
Melanoma Amelanotic 49

Classifications:



External Ids:

Disease Ontology11 DOID:4359
MeSH38 D018328
SNOMED-CT61 70594002
NCIt44 C3802

Summaries for Amelanotic Melanoma

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Wikipedia:70 Amelanotic melanoma is a type of skin cancer in which the cells do not make melanin. They can be... more...

MalaCards based summary: Amelanotic Melanoma, also known as melanoma, amelanotic, is related to skin amelanotic melanoma and relapsing epidemic typhus. An important gene associated with Amelanotic Melanoma is TYR (Tyrosinase), and among its related pathways are AIF Pathway and Gemtuzumab ozogamicin Pathway, Pharmacokinetics/Pharmacodynamics. The drugs cisplatin pwdr and cisplatin have been mentioned in the context of this disorder. Affiliated tissues include skin, brain and lung, and related mouse phenotypes are hearing/vestibular/ear and vision/eye.

Related Diseases for Amelanotic Melanoma

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Diseases related to Amelanotic Melanoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 116)
idRelated DiseaseScoreTop Affiliating Genes
1skin amelanotic melanoma12.0
2relapsing epidemic typhus10.5KIT, S100B
3hypotonia10.5S100B, VIM
4anaplastic oligoastrocytoma10.5S100B, VIM
5vulvar sarcoma10.5KIT, TYR
6exstrophy-epispadias complex10.5S100B, VIM
7absence of fingerprints congenital milia10.5S100B, VIM
8lymphangiosarcoma10.5S100B, VIM
9fraxf syndrome10.5S100B, VIM
10chondroblastoma10.5S100B, VIM
11breast papillary carcinoma10.5KIT, S100B
12pediculus humanus capitis infestation10.5S100B, VIM
13malignant cystic nephroma10.5S100B, VIM
14lumbar plexus neoplasm10.5S100B, VIM
15subependymal giant cell astrocytoma10.5S100B, VIM
16bartholin's gland benign neoplasm10.4S100B, VIM
17malignant adenofibroma10.4S100B, VIM
18eccrine papillary adenoma10.4S100B, VIM
19sclerosing liposarcoma10.4S100B, VIM
20chronic end-stage hepatitis c10.4KIT, VIM
21esophagus leiomyosarcoma10.4KIT, TYR
22gallbladder adenoma10.4S100B, VIM
23skin glomangioma10.4S100B, VIM
24pineal parenchymal tumor of intermediate differenciation10.4S100B, VIM
25focal chorioretinitis10.4KIT, VIM
26tooth erosion10.4KIT, VIM
27pauciarticular onset juvenile idiopathic arthritis10.4S100B, VIM
28osteopetrosis and infantile neuroaxonal dystrophy10.4S100B, VIM
292q33.1 microdeletion syndrome10.4BRAF, VIM
30l-cell glucagon-like peptide producing tumor10.4S100B, VIM
31epithelioid type angiomyolipoma10.4KIT, TYR
32central centrifugal cicatricial alopecia10.4S100B, VIM
33parachordoma10.4KIT, VIM
34laryngeal disease10.4KIT, VIM
35dens in dente and palatal invaginations10.4S100B, VIM
36hypersplenism10.4BRAF, KIT
37perivascular epithelioid cell tumor10.4KIT, VIM
38novak syndrome10.4S100B, VIM
39skin sarcoma10.4BRAF, VIM
40pineoblastoma10.3BRAF, VIM
41glioma susceptibility 110.3S100B, VIM
42acute serous otitis media10.3S100B, VIM
43parotid gland adenoid cystic carcinoma10.3BRAF, KIT
44gallbladder leiomyosarcoma10.3S100B, VIM
45ovarian surface papilloma10.3BRAF, VIM
46adenomyoma of uterine corpus10.3S100B, VIM
47frontal sinus squamous cell carcinoma10.3KIT, VIM
48anus leiomyosarcoma10.3S100B, VIM
49autism susceptibility 1610.3TYR, TYRP1
50duodenal obstruction10.3KIT, VIM

Graphical network of the top 20 diseases related to Amelanotic Melanoma:



Diseases related to amelanotic melanoma

Symptoms for Amelanotic Melanoma

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Drugs & Therapeutics for Amelanotic Melanoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Amelanotic Melanoma

Inferred drug relations via UMLS67/NDF-RT45:


Cochrane evidence based reviews: melanoma, amelanotic

Genetic Tests for Amelanotic Melanoma

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Anatomical Context for Amelanotic Melanoma

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MalaCards organs/tissues related to Amelanotic Melanoma:

35
Skin, Brain, Lung, Colon, Testes, Endothelial, Breast

Animal Models for Amelanotic Melanoma or affiliated genes

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MGI Mouse Phenotypes related to Amelanotic Melanoma:

40 (show all 17)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053779.2BRAF, KIT, PARP1, TYRP1
2MP:00053918.6BRAF, KIT, TYR, TYRP1, VIM
3MP:00020068.6BRAF, DRD2, KIT, TYR, TYRP1
4MP:00011868.6BRAF, DRD2, KIT, TYR, TYRP1
5MP:00053678.1BRAF, DRD2, KIT, PARP1, TYR
6MP:00053807.8BRAF, CYCS, KIT, PARP1, TYR, VIM
7MP:00053907.7BRAF, CYCS, DRD2, KIT, TYR, TYRP1
8MP:00107717.6BRAF, DRD2, KIT, PARP1, S100B, TYR
9MP:00053897.6BRAF, DRD2, KIT, PARP1, TYR, TYRP1
10MP:00053847.1BRAF, CYCS, DRD2, KIT, PARP1, TYR
11MP:00053857.0BRAF, CYCS, DRD2, KIT, TYR, VIM
12MP:00053877.0BRAF, CYCS, DRD2, KIT, PARP1, TYR
13MP:00053786.9BRAF, CYCS, DRD2, KIT, PARP1, TYR
14MP:00053766.8BRAF, DRD2, KIT, PARP1, S100B, TYR
15MP:00107686.6BRAF, CYCS, DRD2, KIT, PARP1, TYR
16MP:00036316.4BRAF, CYCS, DRD2, KIT, PARP1, TYR
17MP:00053866.2BRAF, CYCS, DRD2, KIT, PARP1, S100B

Publications for Amelanotic Melanoma

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Articles related to Amelanotic Melanoma:

(show top 50)    (show all 240)
idTitleAuthorsYear
1
Amelanotic melanoma in the bone marrow. (28092878)
2016
2
Amelanotic melanoma in albinism: the power of dermatoscopy. (26290313)
2015
3
Comparative analysis of pathology and boronophenylalanine uptake in experimental orthotopic and heterotopic amelanotic melanoma. (24915302)
2014
4
Amelanotic melanoma masquerading as a pyogenic granuloma: caution warranted. (24914083)
2014
5
Primary amelanotic melanoma of the nasal cavity: a case report. (24452896)
2014
6
Characteristics and survival of patients with invasive amelanotic melanoma in the USA. (23883947)
2013
7
Hyporeflective pagetoid cells: A new clue for amelanotic melanoma diagnosis by reflectance confocal microscopy. (24329036)
2013
8
Vaginal fistula in a patient with relapsed ovarian cancer and amelanotic melanoma. (22593454)
2012
9
Conjunctival amelanotic melanoma--a case report. (22220456)
2011
10
Cytoplasmic immunoreactivity for Ki67 in an invasive amelanotic melanoma--foe or faux pas? (21062343)
2011
11
Amelanotic melanoma presenting as contact dermatitis. (20956099)
2010
12
Nodular amelanotic melanoma. (20445300)
2010
13
Amelanotic melanoma in a New Zealand White Rabbit (Oryctolagus cuniculus). (20460451)
2010
14
Pitfalls in the dermoscopic diagnosis of amelanotic melanoma. (20398822)
2010
15
Malignant amelanotic melanoma of the pleura without primary skin lesion:an autopsy case report. (20035295)
2009
16
Coexistence of amelanotic melanoma and liposarcoma. (20523835)
2009
17
Massive cardiac invasion by amelanotic melanoma with obstructive clinical features. (18372490)
2008
18
Orbital amelanotic melanoma in xeroderma pigmentosum: a rare association. (18711275)
2008
19
Antiproliferative effects of essential oils and their major constituents in human renal adenocarcinoma and amelanotic melanoma cells. (19040575)
2008
20
Unusual presentation of metastatic amelanotic melanoma of unknown primary origin as a solitary breast lump. (18971788)
2008
21
The activity of caspases in spontaneous and camptothecin-induced death of melanotic and amelanotic melanoma cell. (17312383)
2007
22
Spontaneous apoptosis of melanotic and amelanotic melanoma cells in different phases of cell cycle: relation to tumor growth. (16584089)
2006
23
Dermoscopy for "true" amelanotic melanoma: a clinical dermoscopic-pathologic case study. (16443072)
2006
24
Primary treatment of choroidal amelanotic melanoma with photodynamic therapy--comment. (16970777)
2006
25
Amelanotic melanoma in a child with oculocutaneous albinism. (12825234)
2003
26
Progressive appearance of pigmentation in amelanotic melanoma lesions. (12100494)
2002
27
Metastatic amelanotic melanoma. (12385549)
2002
28
Effect of boron neutron capture therapy for melanotic and amelanotic melanoma transplanted into mouse brain. (11837459)
2002
29
Subungual amelanotic melanoma. (10826092)
2000
30
Selective uptake of para-boronophenylalanine increases in amelanotic melanoma cells transfected by the tyrosinase gene. (10890385)
2000
31
Role of tissue factor pathway inhibitor-2 (TFPI-2) in amelanotic melanoma (C-32) invasion. (11448060)
2000
32
Neurocutaneous melanosis presenting with intracranial amelanotic melanoma. (10219411)
1999
33
What is your diagnosis? Amelanotic melanoma. (10582151)
1999
34
Enhanced melanogenesis induced by tyrosinase gene-transfer increases boron-uptake and killing effect of boron neutron capture therapy for amelanotic melanoma. (9877098)
1998
35
Differential accumulation of iodine-123-iodobenzamide in melanotic and amelanotic melanoma metastases in vivo. (9627332)
1998
36
Visualization of uveal amelanotic melanoma with technetium-99m(V) dimercaptosuccinic acid. (9212896)
1997
37
Amelanotic melanoma and hypercalcaemia. (8958374)
1996
38
An epithelioid cell type of amelanotic melanoma of the pinna in a Fischer-344 rat: a case report. (8992617)
1996
39
Biosynthesis of 12(S)-hydroxyeicosatetraenoic acid by B16 amelanotic melanoma cells is a determinant of their metastatic potential. (8145526)
1994
40
Plasmodium falciparum: the effect of pH and Ca2+ concentration on the in vitro cytoadherence of infected erythrocytes to amelanotic melanoma cells. (1915750)
1991
41
The biphasic nature of a human amelanotic melanoma tumour line HT-18. (3151541)
1988
42
Sarcoid granuloma simulating amelanotic melanoma of the iris. (3813356)
1986
43
Cytologic diagnosis of amelanotic melanoma. (3859154)
1985
44
Effect of antiplatelet antibody on the development of pulmonary metastases following injection of CT26 colon adenocarcinoma, Lewis lung carcinoma, and B16 amelanotic melanoma tumor cells into mice. (6744304)
1984
45
Plasmodium falciparum malaria. An amelanotic melanoma cell line bears receptors for the knob ligand on infected erythrocytes. (7047567)
1982
46
Amelanotic melanoma of the lung and brain with fenestrated intrinsic tumor capillaries. (9760980)
1981
47
Comparison of the antigenicity of melanotic and amelanotic melanoma cells after the release of surface glycoproteins by trypsin. (7192976)
1980
48
Amelanotic melanoma (tapioca melanoma) of the iris. (532814)
1979
49
Detection and quantitation of 5-S-cysteinyldopa in melanotic and amelanotic melanoma in comparison with nonpigment cell tumors and it's urinary excretion. (120380)
1979
50
A clinicopathologic study of amelanotic melanoma. (5086000)
1972

Variations for Amelanotic Melanoma

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Expression for genes affiliated with Amelanotic Melanoma

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Search GEO for disease gene expression data for Amelanotic Melanoma.

Pathways for genes affiliated with Amelanotic Melanoma

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GO Terms for genes affiliated with Amelanotic Melanoma

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Cellular components related to Amelanotic Melanoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1melanosome membraneGO:00331629.8TYR, TYRP1

Biological processes related to Amelanotic Melanoma according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1melanocyte differentiationGO:003031810.0KIT, TYRP1
2melanin biosynthetic processGO:004243810.0TYR, TYRP1
3myeloid progenitor cell differentiationGO:00023189.9BRAF, KIT
4thymus developmentGO:00485389.9BRAF, TYR
5long-term synaptic potentiationGO:00602919.7BRAF, S100B
6visual learningGO:00085428.9BRAF, DRD2, KIT
7pigmentationGO:00434738.4DRD2, KIT, TYR, TYRP1

Molecular functions related to Amelanotic Melanoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein homodimerization activityGO:00428038.4DRD2, KIT, S100B, TYR, TYRP1
2protein heterodimerization activityGO:00469828.3BRAF, DRD2, TYR, TYRP1
3identical protein bindingGO:00428027.9BRAF, DRD2, PARP1, S100B, VIM

Sources for Amelanotic Melanoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet