MCID: AML001
MIFTS: 40

Amelanotic Melanoma malady

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Amelanotic Melanoma

Aliases & Descriptions for Amelanotic Melanoma:

Name: Amelanotic Melanoma 12 14
Melanoma, Amelanotic 42 69
Amelanotic Skin Melanoma 69
Melanoma Amelanotic 52

Classifications:



External Ids:

Disease Ontology 12 DOID:4359
MeSH 42 D018328
NCIt 47 C3802
SNOMED-CT 64 70594002
UMLS 69 C0206735

Summaries for Amelanotic Melanoma

MalaCards based summary : Amelanotic Melanoma, also known as melanoma, amelanotic, is related to skin amelanotic melanoma and melanoma. An important gene associated with Amelanotic Melanoma is TYR (Tyrosinase), and among its related pathways/superpathways are Endometrial cancer and Apoptosis and survival Caspase cascade. Affiliated tissues include skin, lung and brain, and related phenotypes are behavior/neurological and cellular

Wikipedia : 71 Amelanotic melanoma is a type of skin cancer in which the cells do not make melanin. They can be... more...

Related Diseases for Amelanotic Melanoma

Diseases related to Amelanotic Melanoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 108)
id Related Disease Score Top Affiliating Genes
1 skin amelanotic melanoma 12.0
2 melanoma 10.9
3 invasive mole 10.3 KIT S100B
4 monkeypox 10.2 KIT S100B
5 verrucous papilloma 10.2 KIT TYR
6 vulval paget's disease 10.2 KIT TYR
7 precursor t-lymphoblastic lymphoma/leukemia 10.2 KIT S100B
8 lupus - neurological sequelae 10.2 S100B VIM
9 benign schwannoma 10.2 S100B VIM
10 myoma 10.2 S100B VIM
11 jejunal neuroendocrine tumor 10.2 S100B VIM
12 spleen angiosarcoma 10.2 S100B VIM
13 postgerminal center chronic lymphocytic leukemia/small lymphocytic lymphoma 10.2 S100B VIM
14 microinvasive cervical squamous cell carcinoma 10.2 S100B VIM
15 subglottis verrucous carcinoma 10.2 S100B VIM
16 conjunctival cancer 10.2 S100B VIM
17 intracranial sinus thrombosis 10.2 KIT VIM
18 clear cell ependymoma 10.2 S100B VIM
19 behcet's syndrome arthropathy 10.2 S100B VIM
20 marfanoid hypermobility syndrome 10.2 KIT VIM
21 sternum cancer 10.2 S100B VIM
22 aneurysm of sinus of valsalva 10.2 S100B VIM
23 cavernous sinus meningioma 10.2 S100B VIM
24 vulvar squamous papilloma 10.2 S100B VIM
25 liver angiosarcoma 10.2 KIT VIM
26 hypogonadotropic hypogonadism-retinitis pigmentosa syndrome 10.2 S100B VIM
27 uterine hypoplasia 10.2 KIT VIM
28 mediastinum liposarcoma 10.2 S100B VIM
29 vaginal yolk sac tumor 10.2 KIT TYR
30 dyslexia 10.2 S100B VIM
31 alcohol-induced mental disorder 10.2 KIT VIM
32 acute disseminated encephalomyelitis 10.2 BRAF KIT
33 sebaceous adenoma 10.2 KIT VIM
34 skin glomus tumor 10.2 S100B VIM
35 gallbladder disease 10.2 TYR TYRP1
36 onychocytic matricoma 10.2 S100B VIM
37 mesenchymoma 10.2 KIT VIM
38 myxopapillary ependymoma 10.2 BRAF VIM
39 autosomal recessive stickler syndrome 10.2 BRAF VIM
40 progressive multifocal leukoencephalopathy 10.1 BRAF VIM
41 pilar sheath acanthoma 10.1 KIT VIM
42 gastrointestinal system cancer 10.1 S100B VIM
43 craniosynostosis 6 10.1 TYR TYRP1
44 lung mucoepidermoid carcinoma 10.1 BRAF KIT
45 inverted follicular keratosis 10.1 CYCS PARP1
46 lymphangiosarcoma 10.1 BRAF VIM
47 childhood brain germinoma 10.1 S100B VIM
48 fitz-hugh-curtis syndrome 10.1 KIT VIM
49 albinism 10.1
50 desmoid tumor 10.1 S100B VIM

Graphical network of the top 20 diseases related to Amelanotic Melanoma:



Diseases related to Amelanotic Melanoma

Symptoms & Phenotypes for Amelanotic Melanoma

MGI Mouse Phenotypes related to Amelanotic Melanoma:

44 (show all 18)
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.23 PARP1 S100B TYR TYRP1 VIM BRAF
2 cellular MP:0005384 10.1 KIT PARP1 TYR VIM BRAF CYCS
3 homeostasis/metabolism MP:0005376 10.1 BRAF DRD2 KIT PARP1 S100B TYR
4 growth/size/body region MP:0005378 10.07 BRAF CYCS DRD2 KIT PARP1 TYR
5 cardiovascular system MP:0005385 10.04 BRAF CYCS DRD2 KIT TYR VIM
6 mortality/aging MP:0010768 10.03 BRAF CYCS DRD2 KIT PARP1 TYR
7 immune system MP:0005387 10.02 BRAF CYCS DRD2 KIT PARP1 TYR
8 embryo MP:0005380 10.01 BRAF CYCS KIT PARP1 TYR VIM
9 integument MP:0010771 10 BRAF DRD2 KIT PARP1 S100B TYR
10 nervous system MP:0003631 9.97 PARP1 TYR TYRP1 VIM BRAF CYCS
11 craniofacial MP:0005382 9.95 BRAF CYCS KIT TYR TYRP1
12 hearing/vestibular/ear MP:0005377 9.91 BRAF KIT PARP1 TYR TYRP1
13 neoplasm MP:0002006 9.8 BRAF DRD2 KIT TYR TYRP1
14 pigmentation MP:0001186 9.72 BRAF DRD2 KIT TYR TYRP1
15 reproductive system MP:0005389 9.7 BRAF DRD2 KIT PARP1 TYR TYRP1
16 renal/urinary system MP:0005367 9.65 BRAF DRD2 KIT PARP1 TYR
17 skeleton MP:0005390 9.43 BRAF CYCS DRD2 KIT TYR TYRP1
18 vision/eye MP:0005391 9.02 BRAF KIT TYR TYRP1 VIM

Drugs & Therapeutics for Amelanotic Melanoma

Search Clinical Trials , NIH Clinical Center for Amelanotic Melanoma

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: melanoma, amelanotic

Genetic Tests for Amelanotic Melanoma

Anatomical Context for Amelanotic Melanoma

MalaCards organs/tissues related to Amelanotic Melanoma:

39
Skin, Lung, Brain, Colon, Testes, Endothelial, Breast

Publications for Amelanotic Melanoma

Articles related to Amelanotic Melanoma:

(show top 50) (show all 240)
id Title Authors Year
1
Amelanotic melanoma in the bone marrow. ( 28092878 )
2016
2
Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Reversion or promotion of malignancy by inducing melanogenesis or metastasis. ( 27206672 )
2016
3
Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Upregulation of antioxidant genes correlates with regression of melanoma malignancy and with malignant progression when downregulated. ( 27206673 )
2016
4
Amelanotic Melanoma in the Vicinity of Acquired Melanocytic Nevi and not Arising from Agminated Melanocytic Nevi: Masquerading as Pyogenic Granuloma. ( 26955141 )
2016
5
Delivery of a hydrophobic phthalocyanine photosensitizer using PEGylated gold nanoparticle conjugates for the in vivo photodynamic therapy of amelanotic melanoma. ( 27064601 )
2016
6
Establishment and characterization of a transplantable tumor line (RMM) and cell line (RMM-C) from a malignant amelanotic melanoma in the F344 rat, with particular reference to galectin-3 expression in vivo and in vitro. ( 26949998 )
2016
7
BILATERALLY SYMMETRICAL ORAL AMELANOTIC MELANOMA IN A BOA CONSTRICTOR (BOA CONSTRICTOR CONSTRICTOR). ( 26352976 )
2015
8
Polarized light dermoscopy to aid in the diagnosis of new pink lesions in an amelanotic melanoma survivor. ( 26568348 )
2015
9
EFFECTS OF ZINGIBER OFFICINALE ROSCOE FRESH EXTRACT ON AMELANOTIC MELANOMA AND NORMAL SKIN FIBROBLASTS. ( 26204672 )
2015
10
Pitfalls in the dermoscopic diagnosis of amelanotic melanoma. ( 25500029 )
2015
11
Metastatic amelanotic melanoma with occult primary masquerading as sarcoma. ( 25859510 )
2015
12
Intracranial amelanotic melanoma: a case report with literature review. ( 25963017 )
2015
13
Amelanotic melanoma in albinism: the power of dermatoscopy. ( 26290313 )
2015
14
Amelanotic melanoma mimicking an atypical fibrohistiocytic lesion. ( 25993406 )
2015
15
Amelanotic Melanoma Presenting with Plasmacytoid Morphology and BRAF V600 Mutation. ( 26266008 )
2015
16
Amelanotic Melanoma Arising within Conjunctival Melanocytic Intraepithelial Neoplasia Sine Pigmento. ( 26498081 )
2015
17
Parotid metastasis of an amelanotic melanoma of the scalp: The great masquerader. ( 26348327 )
2015
18
Amelanotic melanoma masquerading as a pyogenic granuloma: caution warranted. ( 24914083 )
2014
19
Comparative analysis of pathology and boronophenylalanine uptake in experimental orthotopic and heterotopic amelanotic melanoma. ( 24915302 )
2014
20
Amelanotic melanoma mimicking cutaneous epitheliomas. ( 24629365 )
2014
21
Amelanotic melanoma masquerading as a superficial small round cell tumor: a diagnostic challenge. ( 25484414 )
2014
22
A novel BRAF mutation in association with primary amelanotic melanoma with oral metastases. ( 24393566 )
2014
23
Primary central nervous system amelanotic melanoma in a Hispanic male: Case report. ( 25031666 )
2014
24
Primary amelanotic melanoma of the nasal cavity: a case report. ( 24452896 )
2014
25
Oral amelanotic melanoma of the maxilla. ( 25628704 )
2014
26
Amelanotic melanoma: a case with chr 9 monosomy. ( 24965431 )
2014
27
BRAF and KIT somatic mutations are present in amelanotic melanoma. ( 23938765 )
2013
28
Diagnostic usefulness of findings in Doppler sonography for amelanotic melanoma. ( 23802993 )
2013
29
Primary amelanotic melanoma of the rectum mimicking adenocarcinoma. ( 23919101 )
2013
30
Amelanotic melanoma masquerading as a granular cell lesion. ( 23533832 )
2013
31
Reflectance confocal microscopy in the diagnosis of partially and completely amelanotic melanoma: report on seven cases. ( 22324783 )
2013
32
Subungual acrolentiginous amelanotic melanoma treated with amputation of the distal and middle phalanges. ( 23591855 )
2013
33
Amelanotic melanoma of the tongue. ( 23798843 )
2013
34
Hyporeflective pagetoid cells: A new clue for amelanotic melanoma diagnosis by reflectance confocal microscopy. ( 24329036 )
2013
35
Amelanotic melanoma mimicking keratoacanthoma: the diagnostic role of dermoscopy. ( 23113565 )
2013
36
The PDT activity of free and pegylated pheophorbide a against an amelanotic melanoma transplanted in C57/BL6 mice. ( 22688292 )
2013
37
Characteristics and survival of patients with invasive amelanotic melanoma in the USA. ( 23883947 )
2013
38
Proximal atypical lentigo as a clue to amelanotic melanoma: a novel warning sign in the evaluation of monodactylous onychodystrophy. ( 23647618 )
2013
39
Primary amelanotic melanoma of vulva in a young, lactating female. ( 23450061 )
2012
40
Malignant amelanotic melanoma--a diagnostic surprise: Flurodeoxyglocose Positron Emission Tomography-Computed Tomography and immunohistochemistry clinch the 'final diagnosis'. ( 23174735 )
2012
41
Amelanotic melanoma: a detailed morphologic analysis with clinicopathologic correlation of 75 cases. ( 22050235 )
2012
42
Vaginal fistula in a patient with relapsed ovarian cancer and amelanotic melanoma. ( 22593454 )
2012
43
Dermoscopy, reflectance confocal microscopy and histopathology of an amelanotic melanoma from an individual heterozygous for MC1R and tyrosinase variant alleles. ( 22497519 )
2012
44
Metastatic amelanotic melanoma of the jejunum diagnosed on capsule endoscopy. ( 24683379 )
2012
45
A rare case of endobronchial amelanotic melanoma. ( 21317747 )
2011
46
A rare tumor of the face: malignant nodular hidradenoma with dermoscopic features mimicking amelanotic melanoma. ( 21561586 )
2011
47
Conjunctival amelanotic melanoma--a case report. ( 22220456 )
2011
48
Metastatic amelanotic melanoma of larynx-hypopharynx. ( 21493402 )
2011
49
Cytoplasmic immunoreactivity for Ki67 in an invasive amelanotic melanoma--foe or faux pas? ( 21062343 )
2011
50
In situ amelanotic melanoma of the nail unit mimicking lichen planus: report of 3 cases. ( 20404232 )
2010

Variations for Amelanotic Melanoma

Expression for Amelanotic Melanoma

Search GEO for disease gene expression data for Amelanotic Melanoma.

Pathways for Amelanotic Melanoma

GO Terms for Amelanotic Melanoma

Cellular components related to Amelanotic Melanoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 melanosome membrane GO:0033162 8.62 TYR TYRP1

Biological processes related to Amelanotic Melanoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 response to cAMP GO:0051591 9.43 BRAF TYR
2 thymus development GO:0048538 9.4 BRAF TYR
3 long-term synaptic potentiation GO:0060291 9.37 BRAF S100B
4 melanocyte differentiation GO:0030318 9.32 KIT TYRP1
5 melanin biosynthetic process GO:0042438 9.26 TYR TYRP1
6 myeloid progenitor cell differentiation GO:0002318 9.16 BRAF KIT
7 visual learning GO:0008542 9.13 BRAF DRD2 KIT
8 pigmentation GO:0043473 8.92 DRD2 KIT TYR TYRP1

Molecular functions related to Amelanotic Melanoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 metal ion binding GO:0046872 9.8 BRAF CYCS KIT PARP1 S100B TYR
2 protein heterodimerization activity GO:0046982 9.46 BRAF DRD2 TYR TYRP1
3 identical protein binding GO:0042802 9.35 BRAF DRD2 PARP1 S100B VIM
4 protein homodimerization activity GO:0042803 9.02 DRD2 KIT S100B TYR TYRP1

Sources for Amelanotic Melanoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
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42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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