MCID: AML001
MIFTS: 39

Amelanotic Melanoma malady

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Amelanotic Melanoma

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Aliases & Descriptions for Amelanotic Melanoma:

Name: Amelanotic Melanoma 11 13
Melanoma, Amelanotic 39 68
 
Amelanotic Skin Melanoma 68
Melanoma Amelanotic 50

Classifications:



External Ids:

Disease Ontology11 DOID:4359
MeSH39 D018328
SNOMED-CT62 70594002
NCIt45 C3802

Summaries for Amelanotic Melanoma

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Wikipedia:71 Amelanotic melanoma is a type of skin cancer in which the cells do not make melanin. They can be... more...

MalaCards based summary: Amelanotic Melanoma, also known as melanoma, amelanotic, is related to skin amelanotic melanoma and relapsing epidemic typhus. An important gene associated with Amelanotic Melanoma is TYR (Tyrosinase), and among its related pathways are AIF Pathway and Gemtuzumab ozogamicin Pathway, Pharmacokinetics/Pharmacodynamics. The drugs cisplatin pwdr and cisplatin have been mentioned in the context of this disorder. Affiliated tissues include skin, brain and lung, and related mouse phenotypes are hearing/vestibular/ear and vision/eye.

Related Diseases for Amelanotic Melanoma

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Diseases related to Amelanotic Melanoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 116)
idRelated DiseaseScoreTop Affiliating Genes
1skin amelanotic melanoma12.0
2relapsing epidemic typhus10.5KIT, S100B
3hypotonia10.5S100B, VIM
4anaplastic oligoastrocytoma10.5S100B, VIM
5vulvar sarcoma10.5KIT, TYR
6exstrophy-epispadias complex10.5S100B, VIM
7absence of fingerprints congenital milia10.5S100B, VIM
8lymphangiosarcoma10.5S100B, VIM
9fraxf syndrome10.5S100B, VIM
10chondroblastoma10.5S100B, VIM
11breast papillary carcinoma10.5KIT, S100B
12pediculus humanus capitis infestation10.5S100B, VIM
13malignant cystic nephroma10.5S100B, VIM
14lumbar plexus neoplasm10.5S100B, VIM
15subependymal giant cell astrocytoma10.5S100B, VIM
16bartholin's gland benign neoplasm10.4S100B, VIM
17malignant adenofibroma10.4S100B, VIM
18eccrine papillary adenoma10.4S100B, VIM
19sclerosing liposarcoma10.4S100B, VIM
20chronic end-stage hepatitis c10.4KIT, VIM
21esophagus leiomyosarcoma10.4KIT, TYR
22gallbladder adenoma10.4S100B, VIM
23skin glomangioma10.4S100B, VIM
24pineal parenchymal tumor of intermediate differenciation10.4S100B, VIM
25focal chorioretinitis10.4KIT, VIM
26tooth erosion10.4KIT, VIM
27pauciarticular onset juvenile idiopathic arthritis10.4S100B, VIM
28osteopetrosis and infantile neuroaxonal dystrophy10.4S100B, VIM
292q33.1 microdeletion syndrome10.4BRAF, VIM
30l-cell glucagon-like peptide producing tumor10.4S100B, VIM
31epithelioid type angiomyolipoma10.4KIT, TYR
32central centrifugal cicatricial alopecia10.4S100B, VIM
33parachordoma10.4KIT, VIM
34laryngeal disease10.4KIT, VIM
35dens in dente and palatal invaginations10.4S100B, VIM
36hypersplenism10.4BRAF, KIT
37perivascular epithelioid cell tumor10.4KIT, VIM
38novak syndrome10.4S100B, VIM
39skin sarcoma10.4BRAF, VIM
40pineoblastoma10.3BRAF, VIM
41glioma susceptibility 110.3S100B, VIM
42acute serous otitis media10.3S100B, VIM
43parotid gland adenoid cystic carcinoma10.3BRAF, KIT
44gallbladder leiomyosarcoma10.3S100B, VIM
45ovarian surface papilloma10.3BRAF, VIM
46adenomyoma of uterine corpus10.3S100B, VIM
47frontal sinus squamous cell carcinoma10.3KIT, VIM
48anus leiomyosarcoma10.3S100B, VIM
49autism susceptibility 1610.3TYR, TYRP1
50duodenal obstruction10.3KIT, VIM

Graphical network of the top 20 diseases related to Amelanotic Melanoma:



Diseases related to amelanotic melanoma

Symptoms & Phenotypes for Amelanotic Melanoma

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MGI Mouse Phenotypes related to Amelanotic Melanoma according to GeneCards Suite gene sharing:

41 (show all 17)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053779.2BRAF, KIT, PARP1, TYRP1
2MP:00053918.6BRAF, KIT, TYR, TYRP1, VIM
3MP:00020068.6BRAF, DRD2, KIT, TYR, TYRP1
4MP:00011868.6BRAF, DRD2, KIT, TYR, TYRP1
5MP:00053678.1BRAF, DRD2, KIT, PARP1, TYR
6MP:00053807.8BRAF, CYCS, KIT, PARP1, TYR, VIM
7MP:00053907.7BRAF, CYCS, DRD2, KIT, TYR, TYRP1
8MP:00107717.6BRAF, DRD2, KIT, PARP1, S100B, TYR
9MP:00053897.6BRAF, DRD2, KIT, PARP1, TYR, TYRP1
10MP:00053847.1BRAF, CYCS, DRD2, KIT, PARP1, TYR
11MP:00053857.0BRAF, CYCS, DRD2, KIT, TYR, VIM
12MP:00053877.0BRAF, CYCS, DRD2, KIT, PARP1, TYR
13MP:00053786.9BRAF, CYCS, DRD2, KIT, PARP1, TYR
14MP:00053766.8BRAF, DRD2, KIT, PARP1, S100B, TYR
15MP:00107686.6BRAF, CYCS, DRD2, KIT, PARP1, TYR
16MP:00036316.4BRAF, CYCS, DRD2, KIT, PARP1, TYR
17MP:00053866.2BRAF, CYCS, DRD2, KIT, PARP1, S100B

Drugs & Therapeutics for Amelanotic Melanoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Amelanotic Melanoma

Inferred drug relations via UMLS68/NDF-RT46:


Cochrane evidence based reviews: melanoma, amelanotic

Genetic Tests for Amelanotic Melanoma

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Anatomical Context for Amelanotic Melanoma

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MalaCards organs/tissues related to Amelanotic Melanoma:

36
Skin, Brain, Lung, Colon, Testes, Endothelial, Breast

Publications for Amelanotic Melanoma

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Articles related to Amelanotic Melanoma:

(show top 50)    (show all 240)
idTitleAuthorsYear
1
Amelanotic melanoma in the bone marrow. (28092878)
2016
2
Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Upregulation of antioxidant genes correlates with regression of melanoma malignancy and with malignant progression when downregulated. (27206673)
2016
3
Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Reversion or promotion of malignancy by inducing melanogenesis or metastasis. (27206672)
2016
4
Amelanotic Melanoma in the Vicinity of Acquired Melanocytic Nevi and not Arising from Agminated Melanocytic Nevi: Masquerading as Pyogenic Granuloma. (26955141)
2016
5
Delivery of a hydrophobic phthalocyanine photosensitizer using PEGylated gold nanoparticle conjugates for the in vivo photodynamic therapy of amelanotic melanoma. (27064601)
2016
6
Establishment and characterization of a transplantable tumor line (RMM) and cell line (RMM-C) from a malignant amelanotic melanoma in the F344 rat, with particular reference to galectin-3 expression in vivo and in vitro. (26949998)
2016
7
Amelanotic melanoma in albinism: the power of dermatoscopy. (26290313)
2015
8
Amelanotic Melanoma Presenting with Plasmacytoid Morphology and BRAF V600 Mutation. (26266008)
2015
9
Parotid metastasis of an amelanotic melanoma of the scalp: The great masquerader. (26348327)
2015
10
BILATERALLY SYMMETRICAL ORAL AMELANOTIC MELANOMA IN A BOA CONSTRICTOR (BOA CONSTRICTOR CONSTRICTOR). (26352976)
2015
11
Metastatic amelanotic melanoma with occult primary masquerading as sarcoma. (25859510)
2015
12
Polarized light dermoscopy to aid in the diagnosis of new pink lesions in an amelanotic melanoma survivor. (26568348)
2015
13
Intracranial amelanotic melanoma: a case report with literature review. (25963017)
2015
14
Amelanotic melanoma mimicking an atypical fibrohistiocytic lesion. (25993406)
2015
15
Pitfalls in the dermoscopic diagnosis of amelanotic melanoma. (25500029)
2015
16
EFFECTS OF ZINGIBER OFFICINALE ROSCOE FRESH EXTRACT ON AMELANOTIC MELANOMA AND NORMAL SKIN FIBROBLASTS. (26204672)
2015
17
Amelanotic Melanoma Arising within Conjunctival Melanocytic Intraepithelial Neoplasia Sine Pigmento. (26498081)
2015
18
Comparative analysis of pathology and boronophenylalanine uptake in experimental orthotopic and heterotopic amelanotic melanoma. (24915302)
2014
19
Amelanotic melanoma masquerading as a pyogenic granuloma: caution warranted. (24914083)
2014
20
Primary amelanotic melanoma of the nasal cavity: a case report. (24452896)
2014
21
Oral amelanotic melanoma of the maxilla. (25628704)
2014
22
Amelanotic melanoma masquerading as a superficial small round cell tumor: a diagnostic challenge. (25484414)
2014
23
Amelanotic melanoma mimicking cutaneous epitheliomas. (24629365)
2014
24
Amelanotic melanoma: a case with chr 9 monosomy. (24965431)
2014
25
Primary central nervous system amelanotic melanoma in a Hispanic male: Case report. (25031666)
2014
26
A novel BRAF mutation in association with primary amelanotic melanoma with oral metastases. (24393566)
2014
27
Characteristics and survival of patients with invasive amelanotic melanoma in the USA. (23883947)
2013
28
Hyporeflective pagetoid cells: A new clue for amelanotic melanoma diagnosis by reflectance confocal microscopy. (24329036)
2013
29
Amelanotic melanoma mimicking keratoacanthoma: the diagnostic role of dermoscopy. (23113565)
2013
30
Amelanotic melanoma masquerading as a granular cell lesion. (23533832)
2013
31
Diagnostic usefulness of findings in Doppler sonography for amelanotic melanoma. (23802993)
2013
32
Proximal atypical lentigo as a clue to amelanotic melanoma: a novel warning sign in the evaluation of monodactylous onychodystrophy. (23647618)
2013
33
Reflectance confocal microscopy in the diagnosis of partially and completely amelanotic melanoma: report on seven cases. (22324783)
2013
34
Amelanotic melanoma of the tongue. (23798843)
2013
35
BRAF and KIT somatic mutations are present in amelanotic melanoma. (23938765)
2013
36
Primary amelanotic melanoma of the rectum mimicking adenocarcinoma. (23919101)
2013
37
The PDT activity of free and pegylated pheophorbide a against an amelanotic melanoma transplanted in C57/BL6 mice. (22688292)
2013
38
Subungual acrolentiginous amelanotic melanoma treated with amputation of the distal and middle phalanges. (23591855)
2013
39
Vaginal fistula in a patient with relapsed ovarian cancer and amelanotic melanoma. (22593454)
2012
40
Amelanotic melanoma: a detailed morphologic analysis with clinicopathologic correlation of 75 cases. (22050235)
2012
41
Metastatic amelanotic melanoma of the jejunum diagnosed on capsule endoscopy. (24683379)
2012
42
Primary amelanotic melanoma of vulva in a young, lactating female. (23450061)
2012
43
Dermoscopy, reflectance confocal microscopy and histopathology of an amelanotic melanoma from an individual heterozygous for MC1R and tyrosinase variant alleles. (22497519)
2012
44
Malignant amelanotic melanoma--a diagnostic surprise: Flurodeoxyglocose Positron Emission Tomography-Computed Tomography and immunohistochemistry clinch the 'final diagnosis'. (23174735)
2012
45
Conjunctival amelanotic melanoma--a case report. (22220456)
2011
46
Cytoplasmic immunoreactivity for Ki67 in an invasive amelanotic melanoma--foe or faux pas? (21062343)
2011
47
A rare case of endobronchial amelanotic melanoma. (21317747)
2011
48
A rare tumor of the face: malignant nodular hidradenoma with dermoscopic features mimicking amelanotic melanoma. (21561586)
2011
49
Metastatic amelanotic melanoma of larynx-hypopharynx. (21493402)
2011
50
Amelanotic melanoma presenting as contact dermatitis. (20956099)
2010

Variations for Amelanotic Melanoma

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Expression for genes affiliated with Amelanotic Melanoma

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Search GEO for disease gene expression data for Amelanotic Melanoma.

Pathways for genes affiliated with Amelanotic Melanoma

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GO Terms for genes affiliated with Amelanotic Melanoma

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Cellular components related to Amelanotic Melanoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1melanosome membraneGO:00331629.8TYR, TYRP1

Biological processes related to Amelanotic Melanoma according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1melanin biosynthetic processGO:004243810.3TYR, TYRP1
2melanocyte differentiationGO:003031810.2KIT, TYRP1
3long-term synaptic potentiationGO:006029110.2BRAF, S100B
4myeloid progenitor cell differentiationGO:000231810.1BRAF, KIT
5thymus developmentGO:004853810.1BRAF, TYR
6pigmentationGO:00434739.3DRD2, KIT, TYR, TYRP1
7visual learningGO:00085428.9BRAF, DRD2, KIT

Molecular functions related to Amelanotic Melanoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein heterodimerization activityGO:00469829.3BRAF, DRD2, TYR, TYRP1
2identical protein bindingGO:00428028.7BRAF, DRD2, PARP1, S100B, VIM
3protein homodimerization activityGO:00428038.4DRD2, KIT, S100B, TYR, TYRP1

Sources for Amelanotic Melanoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet