MCID: AML001
MIFTS: 40

Amelanotic Melanoma malady

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Amelanotic Melanoma

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Aliases & Descriptions for Amelanotic Melanoma:

Name: Amelanotic Melanoma 11 13
Melanoma, Amelanotic 37 66
 
Amelanotic Skin Melanoma 66
Melanoma Amelanotic 48

Classifications:



External Ids:

Disease Ontology11 DOID:4359
MeSH37 D018328
SNOMED-CT60 70594002
NCIt43 C3802

Summaries for Amelanotic Melanoma

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Wikipedia:69 Amelanotic melanoma is a type of skin cancer in which the cells do not make melanin. They can be... more...

MalaCards based summary: Amelanotic Melanoma, also known as melanoma, amelanotic, is related to melanoma and skin amelanotic melanoma. An important gene associated with Amelanotic Melanoma is TYR (Tyrosinase), and among its related pathways are AIF Pathway and Gemtuzumab ozogamicin Pathway, Pharmacokinetics/Pharmacodynamics. The drugs cisplatin and cisplatin pwdr have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and brain, and related mouse phenotypes are pigmentation and neoplasm.

Related Diseases for Amelanotic Melanoma

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Diseases related to Amelanotic Melanoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 108)
idRelated DiseaseScoreTop Affiliating Genes
1melanoma32.4KIT, TYR
2skin amelanotic melanoma12.1
3leukemoid reaction10.6KIT, TYR
4vulvar sarcoma10.6KIT, TYR
5diffuse cutaneous mastocytosis10.5CTSG, KIT
6esophagus leiomyosarcoma10.5KIT, TYR
7hypersplenism10.5BRAF, KIT
8parotid gland adenoid cystic carcinoma10.5BRAF, KIT
9epithelioid type angiomyolipoma10.5KIT, TYR
10relapsing epidemic typhus10.3KIT, S100B
11post-surgical hypoinsulinemia10.3CYCS, KIT
12breast papillary carcinoma10.3KIT, S100B
13ureter inverted papilloma10.3CYCS, PARP1
14albinism10.2
15pyometritis10.2CYCS, PARP1
16oculocutaneous albinism10.2
17chronic end-stage hepatitis c10.1KIT, VIM
182q33.1 microdeletion syndrome10.1BRAF, VIM
19focal chorioretinitis10.1KIT, VIM
20tooth erosion10.1KIT, VIM
21choroiditis10.1
22adenocarcinoma10.1
23pyogenic granuloma10.1
24heavy chain disease10.1KIT, TYR
25parachordoma10.1KIT, VIM
26skin sarcoma10.1BRAF, VIM
27pineoblastoma10.1BRAF, VIM
28laryngeal disease10.1KIT, VIM
29ciliary body spindle cell melanoma10.0KIT, S100B, TYR
30perivascular epithelioid cell tumor10.0KIT, VIM
31ovarian surface papilloma10.0BRAF, VIM
32melanoma metastasis10.0
33endotheliitis10.0
34epicardium cancer10.0BRAF, KIT, S100B
35brain meningioma10.0DRD2, S100B
36frontal sinus squamous cell carcinoma9.9KIT, VIM
37duodenal obstruction9.9KIT, VIM
38hypotonia9.9S100B, VIM
39anaplastic oligoastrocytoma9.9S100B, VIM
40exstrophy-epispadias complex9.9S100B, VIM
41absence of fingerprints congenital milia9.9S100B, VIM
42lymphangiosarcoma9.9S100B, VIM
43fraxf syndrome9.9S100B, VIM
44chondroblastoma9.9S100B, VIM
45pediculus humanus capitis infestation9.9S100B, VIM
46malignant cystic nephroma9.9S100B, VIM
47lumbar plexus neoplasm9.9S100B, VIM
48subependymal giant cell astrocytoma9.9S100B, VIM
49malaria9.9
50rothmund-thomson syndrome9.9

Graphical network of the top 20 diseases related to Amelanotic Melanoma:



Diseases related to amelanotic melanoma

Symptoms for Amelanotic Melanoma

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Drugs & Therapeutics for Amelanotic Melanoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Amelanotic Melanoma

Inferred drug relations via UMLS66/NDF-RT44:


Cochrane evidence based reviews: melanoma, amelanotic

Genetic Tests for Amelanotic Melanoma

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Anatomical Context for Amelanotic Melanoma

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MalaCards organs/tissues related to Amelanotic Melanoma:

34
Skin, Lung, Brain, Colon, Testes, Endothelial, Breast

Animal Models for Amelanotic Melanoma or affiliated genes

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MGI Mouse Phenotypes related to Amelanotic Melanoma:

39 (show all 15)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.3BRAF, DRD2, KIT, TYR
2MP:00020068.8BRAF, CTSG, DRD2, KIT, TYR
3MP:00053678.4BRAF, DRD2, KIT, PARP1, TYR
4MP:00107718.3BRAF, DRD2, KIT, PARP1, S100B, TYR
5MP:00053898.0BRAF, DRD2, KIT, PARP1, TYR, VIM
6MP:00053808.0BRAF, CYCS, KIT, PARP1, TYR, VIM
7MP:00028737.9BRAF, CTSG, DRD2, KIT, S100B, TYR
8MP:00053857.5BRAF, CYCS, DRD2, KIT, TYR, VIM
9MP:00053847.5BRAF, CYCS, DRD2, KIT, PARP1, TYR
10MP:00053977.3BRAF, CTSG, CYCS, DRD2, KIT, PARP1
11MP:00036317.2BRAF, CYCS, DRD2, KIT, PARP1, TYR
12MP:00053877.1BRAF, CTSG, CYCS, DRD2, KIT, PARP1
13MP:00053767.0BRAF, DRD2, KIT, PARP1, S100B, TYR
14MP:00107686.9BRAF, CTSG, CYCS, DRD2, KIT, PARP1
15MP:00053866.2BRAF, CYCS, DRD2, KIT, PARP1, S100B

Publications for Amelanotic Melanoma

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Articles related to Amelanotic Melanoma:

(show top 50)    (show all 239)
idTitleAuthorsYear
1
Amelanotic melanoma in albinism: the power of dermatoscopy. (26290313)
2015
2
Comparative analysis of pathology and boronophenylalanine uptake in experimental orthotopic and heterotopic amelanotic melanoma. (24915302)
2014
3
Amelanotic melanoma masquerading as a pyogenic granuloma: caution warranted. (24914083)
2014
4
Primary amelanotic melanoma of the nasal cavity: a case report. (24452896)
2014
5
Characteristics and survival of patients with invasive amelanotic melanoma in the USA. (23883947)
2013
6
Hyporeflective pagetoid cells: A new clue for amelanotic melanoma diagnosis by reflectance confocal microscopy. (24329036)
2013
7
Vaginal fistula in a patient with relapsed ovarian cancer and amelanotic melanoma. (22593454)
2012
8
Amelanotic melanoma: a detailed morphologic analysis with clinicopathologic correlation of 75 cases. (22050235)
2012
9
Conjunctival amelanotic melanoma--a case report. (22220456)
2011
10
Cytoplasmic immunoreactivity for Ki67 in an invasive amelanotic melanoma--foe or faux pas? (21062343)
2011
11
Amelanotic melanoma presenting as contact dermatitis. (20956099)
2010
12
Nodular amelanotic melanoma. (20445300)
2010
13
Amelanotic melanoma in a New Zealand White Rabbit (Oryctolagus cuniculus). (20460451)
2010
14
Pitfalls in the dermoscopic diagnosis of amelanotic melanoma. (20398822)
2010
15
Malignant amelanotic melanoma of the pleura without primary skin lesion:an autopsy case report. (20035295)
2009
16
Coexistence of amelanotic melanoma and liposarcoma. (20523835)
2009
17
Massive cardiac invasion by amelanotic melanoma with obstructive clinical features. (18372490)
2008
18
Orbital amelanotic melanoma in xeroderma pigmentosum: a rare association. (18711275)
2008
19
Antiproliferative effects of essential oils and their major constituents in human renal adenocarcinoma and amelanotic melanoma cells. (19040575)
2008
20
Unusual presentation of metastatic amelanotic melanoma of unknown primary origin as a solitary breast lump. (18971788)
2008
21
The activity of caspases in spontaneous and camptothecin-induced death of melanotic and amelanotic melanoma cell. (17312383)
2007
22
Spontaneous apoptosis of melanotic and amelanotic melanoma cells in different phases of cell cycle: relation to tumor growth. (16584089)
2006
23
Dermoscopy for "true" amelanotic melanoma: a clinical dermoscopic-pathologic case study. (16443072)
2006
24
Primary treatment of choroidal amelanotic melanoma with photodynamic therapy--comment. (16970777)
2006
25
Amelanotic melanoma in a child with oculocutaneous albinism. (12825234)
2003
26
Progressive appearance of pigmentation in amelanotic melanoma lesions. (12100494)
2002
27
Metastatic amelanotic melanoma. (12385549)
2002
28
Effect of boron neutron capture therapy for melanotic and amelanotic melanoma transplanted into mouse brain. (11837459)
2002
29
Subungual amelanotic melanoma. (10826092)
2000
30
Selective uptake of para-boronophenylalanine increases in amelanotic melanoma cells transfected by the tyrosinase gene. (10890385)
2000
31
Role of tissue factor pathway inhibitor-2 (TFPI-2) in amelanotic melanoma (C-32) invasion. (11448060)
2000
32
Neurocutaneous melanosis presenting with intracranial amelanotic melanoma. (10219411)
1999
33
What is your diagnosis? Amelanotic melanoma. (10582151)
1999
34
Enhanced melanogenesis induced by tyrosinase gene-transfer increases boron-uptake and killing effect of boron neutron capture therapy for amelanotic melanoma. (9877098)
1998
35
Differential accumulation of iodine-123-iodobenzamide in melanotic and amelanotic melanoma metastases in vivo. (9627332)
1998
36
Visualization of uveal amelanotic melanoma with technetium-99m(V) dimercaptosuccinic acid. (9212896)
1997
37
Amelanotic melanoma and hypercalcaemia. (8958374)
1996
38
An epithelioid cell type of amelanotic melanoma of the pinna in a Fischer-344 rat: a case report. (8992617)
1996
39
Biosynthesis of 12(S)-hydroxyeicosatetraenoic acid by B16 amelanotic melanoma cells is a determinant of their metastatic potential. (8145526)
1994
40
Plasmodium falciparum: the effect of pH and Ca2+ concentration on the in vitro cytoadherence of infected erythrocytes to amelanotic melanoma cells. (1915750)
1991
41
The biphasic nature of a human amelanotic melanoma tumour line HT-18. (3151541)
1988
42
Sarcoid granuloma simulating amelanotic melanoma of the iris. (3813356)
1986
43
Cytologic diagnosis of amelanotic melanoma. (3859154)
1985
44
Effect of antiplatelet antibody on the development of pulmonary metastases following injection of CT26 colon adenocarcinoma, Lewis lung carcinoma, and B16 amelanotic melanoma tumor cells into mice. (6744304)
1984
45
Plasmodium falciparum malaria. An amelanotic melanoma cell line bears receptors for the knob ligand on infected erythrocytes. (7047567)
1982
46
Amelanotic melanoma of the lung and brain with fenestrated intrinsic tumor capillaries. (9760980)
1981
47
Comparison of the antigenicity of melanotic and amelanotic melanoma cells after the release of surface glycoproteins by trypsin. (7192976)
1980
48
Amelanotic melanoma (tapioca melanoma) of the iris. (532814)
1979
49
Detection and quantitation of 5-S-cysteinyldopa in melanotic and amelanotic melanoma in comparison with nonpigment cell tumors and it's urinary excretion. (120380)
1979
50
A clinicopathologic study of amelanotic melanoma. (5086000)
1972

Variations for Amelanotic Melanoma

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Expression for genes affiliated with Amelanotic Melanoma

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Search GEO for disease gene expression data for Amelanotic Melanoma.

Pathways for genes affiliated with Amelanotic Melanoma

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GO Terms for genes affiliated with Amelanotic Melanoma

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Biological processes related to Amelanotic Melanoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1myeloid progenitor cell differentiationGO:000231810.2BRAF, KIT
2thymus developmentGO:004853810.0BRAF, TYR
3long-term synaptic potentiationGO:00602919.5BRAF, S100B
4visual learningGO:00085429.2BRAF, DRD2, KIT
5pigmentationGO:00434739.0DRD2, KIT, TYR
6positive regulation of gene expressionGO:00106289.0BRAF, KIT, VIM

Molecular functions related to Amelanotic Melanoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein homodimerization activityGO:00428038.6DRD2, KIT, S100B, TYR
2identical protein bindingGO:00428027.7BRAF, DRD2, PARP1, S100B, VIM

Sources for Amelanotic Melanoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet