MCID: AML004
MIFTS: 31

Ameloblastic Carcinoma

Categories: Rare diseases, Oral diseases, Cancer diseases

Aliases & Classifications for Ameloblastic Carcinoma

MalaCards integrated aliases for Ameloblastic Carcinoma:

Name: Ameloblastic Carcinoma 50 56 69

Characteristics:

Orphanet epidemiological data:

56
ameloblastic carcinoma
Inheritance: Not applicable; Prevalence: <1/1000000 (Worldwide); Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 56  
Rare odontological diseases


External Ids:

Orphanet 56 ORPHA314422
UMLS via Orphanet 70 C1314678
ICD10 via Orphanet 34 C41.1

Summaries for Ameloblastic Carcinoma

MalaCards based summary : Ameloblastic Carcinoma is related to split hand split foot nystagmus and orbital lymphoma, and has symptoms including pain An important gene associated with Ameloblastic Carcinoma is MKI67 (Marker Of Proliferation Ki-67), and among its related pathways/superpathways are MicroRNAs in cancer and DNA Damage. Affiliated tissues include smooth muscle and lung, and related phenotypes are cellular and homeostasis/metabolism

Wikipedia : 72 Ameloblastic carcinoma is a rare form of odontogenic tumor, one that develops in the jawbones from the... more...

Related Diseases for Ameloblastic Carcinoma

Diseases related to Ameloblastic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 64)
id Related Disease Score Top Affiliating Genes
1 split hand split foot nystagmus 10.6 CDKN2A MKI67
2 orbital lymphoma 10.6 CDKN2A MKI67
3 rectal neoplasm 10.5 MKI67 VIM
4 myeloid/lymphoid neoplasm associated with pdgfra rearrangement 10.5 CDKN2A VIM
5 olivopontocerebellar atrophy deafness 10.5 KRT14 VIM
6 pulmonary venoocclusive disease 10.5 KRT14 VIM
7 persian gulf syndrome 10.5 CDKN2A VIM
8 diffuse meningeal melanocytosis 10.5 CDKN2A VIM
9 myoepithelial carcinoma 10.5 MKI67 VIM
10 spindle cell liposarcoma 10.5 CDKN2A VIM
11 childhood oligodendroglioma 10.5 CDKN2A MKI67
12 middle ear squamous cell carcinoma 10.5 CDKN2A KRT14
13 enamel hypoplasia cataract hydrocephaly 10.5 MKI67 VIM
14 spastic ataxia 3 10.5 CDKN2A VIM
15 ductal carcinoma in situ 10.4 CDKN2A KRT14
16 connective tissue benign neoplasm 10.4 KRT14 SLC2A1
17 neonatal respiratory failure 10.4 KRT14 TP63
18 bladder squamous cell carcinoma 10.4 CDKN2A SLC2A1
19 prostate disease 10.4 SLC2A1 VIM
20 vaginal adenoma 10.4 KRT14 TP63
21 liver disease 10.4 KRT14 TP63
22 epicardium cancer 10.4 KRT14 SLC2A1
23 epidermolysa bullosa simplex with muscular dystrophy 10.4 MKI67 VIM
24 c-p angle neurinoma 10.4 CDKN2A SLC2A1
25 vulvar squamous papilloma 10.4 TP63 VIM
26 angelman syndrome due to imprinting defect in 15q11-q13 10.3 CDKN2A VIM
27 mesenchymoma 10.3 TP63 VIM
28 ameloblastoma 10.3
29 anaerobic pneumonia 10.3 CDKN2A KRT14
30 charcot-marie-tooth disease type 2a 10.3 CDKN2A MKI67
31 internal auditory canal lipoma 10.3 CDKN2A MAPK8IP2
32 bullous keratopathy 10.3 KRT14 TP63
33 iridogoniodysgenesis and skeletal anomalies 10.3 HIF1A VIM
34 breast duct papilloma 10.3 KRT14 MKI67
35 long qt syndrome-11 10.2 SLC2A1 VIM
36 hyperpituitarism 10.2 SLC2A1 VIM
37 bladder colloid adenocarcinoma 10.2 CDKN2A MKI67 VIM
38 small cell neuroendocrine carcinoma 10.2 KRT14 VIM
39 gastrointestinal stromal tumor 10.2 CDKN2A MKI67 VIM
40 estrogen-receptor negative breast cancer 10.1 CDKN2A KRT14
41 nominal aphasia 10.1 KRT14 MKI67 TP63
42 plasmodium ovale malaria 10.1 CDKN2A MKI67 TP63
43 autoimmune lymphoproliferative syndrome 10.1 MKI67 SLC2A1 VIM
44 childhood type dermatomyositis 10.1 CDKN2A MKI67 TP63
45 chronic neutrophilic leukemia 10.1 CDKN2A SDC1
46 adamantinous craniopharyngioma 10.1 KRT14 MKI67
47 pseudounicornuate uterus 10.1 MKI67 TP63 VIM
48 esophagus lymphoma 10.1 CDKN2A MKI67 TP63
49 hip subluxation 10.1 MKI67 TP63 VIM
50 polyosteolysis/hyperostosis syndrome 10.1 MKI67 TP63 VIM

Graphical network of the top 20 diseases related to Ameloblastic Carcinoma:



Diseases related to Ameloblastic Carcinoma

Symptoms & Phenotypes for Ameloblastic Carcinoma

UMLS symptoms related to Ameloblastic Carcinoma:


pain

MGI Mouse Phenotypes related to Ameloblastic Carcinoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.98 CDKN2A HIF1A KRT14 SDC1 SLC2A1 TP63
2 homeostasis/metabolism MP:0005376 9.97 CDKN2A HIF1A KRT14 MAPK8IP2 SDC1 SLC2A1
3 mortality/aging MP:0010768 9.92 MAPK8IP2 SDC1 SLC2A1 TP63 VIM CDKN2A
4 endocrine/exocrine gland MP:0005379 9.88 CDKN2A HIF1A KRT14 MAPK8IP2 SDC1 TP63
5 neoplasm MP:0002006 9.65 CDKN2A HIF1A KRT14 SDC1 TP63
6 reproductive system MP:0005389 9.63 CDKN2A KRT14 MAPK8IP2 SDC1 TP63 VIM
7 respiratory system MP:0005388 9.35 VIM CDKN2A HIF1A KRT14 TP63
8 vision/eye MP:0005391 9.1 CDKN2A HIF1A KRT14 MAPK8IP2 TP63 VIM

Drugs & Therapeutics for Ameloblastic Carcinoma

Search Clinical Trials , NIH Clinical Center for Ameloblastic Carcinoma

Genetic Tests for Ameloblastic Carcinoma

Anatomical Context for Ameloblastic Carcinoma

MalaCards organs/tissues related to Ameloblastic Carcinoma:

39
Smooth Muscle, Lung

Publications for Ameloblastic Carcinoma

Articles related to Ameloblastic Carcinoma:

(show top 50) (show all 120)
id Title Authors Year
1
Recurrence and cancerization of ameloblastoma: multivariate analysis of 87 recurrent craniofacial ameloblastoma to assess risk factors associated with early recurrence and secondary ameloblastic carcinoma. ( 28729769 )
2017
2
Ameloblastic Carcinoma: A Rare Malignant Tumour in Maxillofacial Region. ( 28717298 )
2017
3
Pattern of care and impact of prognostic factors in the outcome of ameloblastic carcinoma: a systematic review and individual patient data analysis of 199 cases. ( 28600599 )
2017
4
A Rare Case Report of Spindle Cell Ameloblastic Carcinoma Involving the Mandible. ( 28274070 )
2017
5
Ameloblastic carcinoma of the maxilla: A case report and an updated review of the literature. ( 28105148 )
2016
6
Immunohistochemical expression of K6, K8, K16, K17, K19, maspin, syndecan-1 (CD138), I+-SMA, and Ki-67 in ameloblastoma and ameloblastic carcinoma: diagnostic and prognostic correlations. ( 26972539 )
2016
7
Ameloblastic carcinoma (secondary type) with extensive squamous differentiation areas and dedifferentiated regions. ( 26768075 )
2016
8
Ameloblastic Carcinoma: A Report of Three Cases. ( 27891485 )
2016
9
Treatment of ameloblastoma and ameloblastic carcinoma with radiotherapy. ( 26796877 )
2016
10
Ameloblastic carcinoma: a Brazilian collaborative study of 17 cases. ( 27195964 )
2016
11
Ameloblastic carcinoma of the maxilla: a report of two cases and a review of the literature. ( 26904494 )
2016
12
Immunohistochemical Expression of GLUT-1 and HIF-1I+ in Tooth Germ, Ameloblastoma, and Ameloblastic Carcinoma. ( 27020375 )
2016
13
Massive Skull Base Ameloblastic Carcinoma with Intracranial Extension. ( 27560532 )
2015
14
Single-Fraction Helical Tomotherapy forA Ameloblastic Carcinoma. ( 26272005 )
2015
15
Spindle-cell ameloblastic carcinoma of the maxilla with adenoid cystic carcinoma-like areas: A new variant? ( 26549079 )
2015
16
Spindle cell variant of ameloblastic carcinoma: a case report and review of literature. ( 25939122 )
2015
17
Immunoexpression of Ki-67, MCM2, and MCM3 in Ameloblastoma and Ameloblastic Carcinoma and Their Correlations with Clinical and Histopathological Patterns. ( 26823641 )
2015
18
Expression of the transcription factor PITX2 in ameloblastic carcinoma. ( 25791324 )
2015
19
Ameloblastic Carcinoma: A Case Report. ( 26393226 )
2015
20
Primary ameloblastic carcinoma of the maxilla: A case report and literature review. ( 25436009 )
2015
21
Ameloblastic carcinoma: An effort to abridge this diagnostic challenge! ( 26853419 )
2015
22
Ameloblastic Carcinoma. ( 26126621 )
2015
23
Ameloblastic carcinoma with features of ghost cell odontogenic carcinoma in a patient with suspected Gardner syndrome. ( 25434693 )
2015
24
Ameloblastic carcinoma of the mandible manifesting as an infected odontogenic cyst. ( 25574726 )
2015
25
Spindle cell variant of ameloblastic carcinoma: a case report and literature review. ( 26238174 )
2015
26
Usefulness of (11)C-methionine positron emission tomography for detecting intracranial ameloblastic carcinoma: A case report. ( 25202358 )
2014
27
Prominent response with helical tomotherapy in recurrent ameloblastic carcinoma of maxillary sinus: a case report. ( 25027948 )
2014
28
Ameloblastic carcinoma developing in preexisting ameloblastoma with a mutation of the p53 gene: a case report. ( 24906942 )
2014
29
Ameloblastic carcinoma of mandible: facts and dilemmas. ( 25343557 )
2014
30
Identification of proteins with increased levels in ameloblastic carcinoma. ( 24485979 )
2014
31
Evaluation of SOX2 as a potential marker for ameloblastic carcinoma. ( 24603057 )
2014
32
Ameloblastic carcinoma: An analysis of 12 cases with a review of the literature. ( 25013517 )
2014
33
Ameloblastic carcinoma of the mandible: Report of a case and review. ( 25364189 )
2014
34
A rare case of ameloblastic carcinoma. ( 25255357 )
2014
35
Ameloblastic carcinoma: A case series. ( 25210376 )
2014
36
Ameloblastic carcinoma: A clinicopathologic dilemma - Report of two cases with total review of literature from 1984 to 2012. ( 24987603 )
2014
37
Ameloblastic carcinoma: Report of a rare case. ( 24579073 )
2014
38
Ameloblastic carcinoma of the mandible with clear cell changes: a case report. ( 23713037 )
2013
39
Spindle cell ameloblastic carcinoma in a labrador retriever dog. ( 23229541 )
2013
40
Large ameloblastic carcinoma: A rare case with management. ( 24379872 )
2013
41
Treatment strategy of a huge ameloblastic carcinoma. ( 23348302 )
2013
42
Hypermethylation of p16 tumor-suppressor gene in ameloblastic carcinoma, ameloblastoma, and dental follicles. ( 22705216 )
2013
43
Mandibular ameloblastic carcinoma. ( 24034198 )
2013
44
The use of Gamma Knife stereotactic radiosurgery in the treatment of ameloblastic carcinoma. ( 23726272 )
2013
45
The variability and complexity of ameloblastoma: carcinoma ex ameloblastoma or primary ameloblastic carcinoma. ( 22920533 )
2013
46
Ameloblastic carcinoma, secondary type, of the mandible: a case report. ( 23099227 )
2013
47
Ameloblastic carcinoma in a young patient. ( 24184061 )
2013
48
Alpha smooth muscle actin expression in a case of ameloblastic carcinoma: a case report. ( 24422027 )
2013
49
Mandibular ameloblastic carcinoma in a young patient. ( 22395519 )
2012
50
Ameloblastic carcinoma, primary type: case report, immunohistochemical analysis and literature review. ( 22493395 )
2012

Variations for Ameloblastic Carcinoma

Expression for Ameloblastic Carcinoma

Search GEO for disease gene expression data for Ameloblastic Carcinoma.

Pathways for Ameloblastic Carcinoma

Pathways related to Ameloblastic Carcinoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.97 CDKN2A TP63 VIM
2 11.72 CDKN2A MKI67 TP63 VIM
3 10.82 HIF1A SLC2A1
4 10.53 CDKN2A HIF1A SLC2A1
5
Show member pathways
10.5 CDKN2A TP63

GO Terms for Ameloblastic Carcinoma

Cellular components related to Ameloblastic Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.56 CDKN2A HIF1A KRT14 MAPK8IP2 MKI67 SLC2A1
2 protein complex GO:0043234 8.92 HIF1A MAPK8IP2 SDC1 TP63

Molecular functions related to Ameloblastic Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein C-terminus binding GO:0008022 9.33 MKI67 SDC1 VIM
2 transcription factor activity, transcription factor binding GO:0000989 8.96 HIF1A TP63
3 keratin filament binding GO:1990254 8.62 KRT14 VIM

Sources for Ameloblastic Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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