MCID: AML004
MIFTS: 32

Ameloblastic Carcinoma malady

Categories: Rare diseases, Oral diseases, Cancer diseases

Aliases & Classifications for Ameloblastic Carcinoma

About this section
Sources:
31ICD10 via Orphanet, 48NIH Rare Diseases, 54Orphanet, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Ameloblastic Carcinoma:

Name: Ameloblastic Carcinoma 48 54 68

Characteristics:

Orphanet epidemiological data:

54
ameloblastic carcinoma:
Inheritance: Not applicable; Prevalence: <1/1000000 (Worldwide); Age of onset: All ages; Age of death: any age

Classifications:



External Ids:

Orphanet54 ORPHA314422
UMLS via Orphanet69 C1314678
ICD10 via Orphanet31 C41.1

Summaries for Ameloblastic Carcinoma

About this section
Wikipedia:71 Ameloblastic carcinoma is a rare form of odontogenic tumor, one that develops in the jawbones from the... more...

MalaCards based summary: Ameloblastic Carcinoma is related to ameloblastoma and conjunctival cancer, and has symptoms including pain An important gene associated with Ameloblastic Carcinoma is MKI67 (Marker Of Proliferation Ki-67), and among its related pathways are TP53 Network and Photodynamic therapy-induced HIF-1 survival signaling. Affiliated tissues include smooth muscle and lung, and related mouse phenotypes are respiratory system and integument.

Related Diseases for Ameloblastic Carcinoma

About this section

Diseases related to Ameloblastic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 55)
idRelated DiseaseScoreTop Affiliating Genes
1ameloblastoma10.3
2conjunctival cancer10.2KRT14, VIM
3onychodystrophy-anonychia10.2KRT14, VIM
4spondylarthropathy10.2CDKN2A, MKI67
513q12.3 microdeletion syndrome10.2CDKN2A, VIM
6neonatal respiratory failure10.2KRT14, TP63
7oro-mandibular-limb hypogenesis syndrome10.2CDKN2A, MKI67
8vulvar squamous papilloma10.2TP63, VIM
9immunodeficiency due to a classical component pathway complement deficiency10.2CDKN2A, VIM
10secondary corneal edema10.2KRT14, TP63
11mesenchymoma10.2TP63, VIM
12lung combined type small cell carcinoma10.2KRT14, TP63
13enchondromatosis dwarfism deafness10.2MKI67, VIM
14avian influenza10.2CDKN2A, VIM
15lymphedema10.2KRT14, TP63
16vulvar alveolar soft part sarcoma10.2CDKN2A, KRT14
17mediastinum liposarcoma10.2CDKN2A, VIM
18spastic ataxia 510.2CDKN2A, VIM
19spinal cord oligodendroglioma10.2CDKN2A, MKI67
20thymus squamous cell carcinoma10.2CDKN2A, KRT14
21ossifying fibromyxoid tumor10.2CDKN2A, VIM
22epidermolysis bullosa simplex-mp10.1KRT14, TP63
23heavy chain disease10.1KRT14, SLC2A1
24subependymal glioma10.1KRT14, MKI67, VIM
25mongolian spot10.1KRT14, SLC2A1
26uterine hypoplasia10.1MKI67, TP63, VIM
27retrograde amnesia10.1KRT14, MKI67, TP63
28popliteal pterygium syndrome, bartsocas-papas type10.1MKI67, TP63, VIM
29his bundle tachycardia10.1MKI67, TP63, VIM
30testicular granulosa cell tumor10.1KRT14, TP63, VIM
31cauda equina intradural extramedullary astrocytoma10.1KRT14, TP63, VIM
32estrogen-receptor positive breast cancer10.1CDKN2A, KRT14
33scirrhous adenocarcinoma10.1KRT14, TP63, VIM
34bladder adenocarcinoma10.1CDKN2A, MKI67, VIM
35hypertrophy of breast10.1MKI67, SDC1
36mediastinum angiosarcoma10.1KRT14, TP63, VIM
37vascular myelopathy10.1CDKN2A, SLC2A1
38charcot-marie-tooth disease type 2n10.1CDKN2A, MKI67
39plasmodium ovale malaria10.1CDKN2A, MKI67, TP63
40caroli disease10.1CDKN2A, KRT14, VIM
41gastrointestinal stromal tumor10.1CDKN2A, MKI67, VIM
42childhood-onset cerebral x-linked adrenoleukodystrophy10.1CDKN2A, MKI67, TP63
43sternum lymphoma10.1CDKN2A, MAPK8IP2
44isolated anterior cervical hypertrichosis10.1HIF1A, VIM
45autonomic nervous system neoplasm10.0CDKN2A, KRT14, TP63
46orofaciodigital syndrome iv10.0MKI67, SLC2A1, VIM
47mitochondrial encephalomyopathy10.0CDKN2A, TP63
48hyperpituitarism10.0SLC2A1, VIM
49central nervous system leiomyosarcoma9.9HIF1A, TP63
50ocular melanoma9.9CDKN2A, KRT14, MKI67, TP63

Graphical network of the top 20 diseases related to Ameloblastic Carcinoma:



Diseases related to ameloblastic carcinoma

Symptoms & Phenotypes for Ameloblastic Carcinoma

About this section

UMLS symptoms related to Ameloblastic Carcinoma:


pain

MGI Mouse Phenotypes related to Ameloblastic Carcinoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053889.1CDKN2A, HIF1A, KRT14, TP63, VIM
2MP:00107719.0CDKN2A, HIF1A, KRT14, SDC1, TP63
3MP:00020069.0CDKN2A, HIF1A, KRT14, SDC1, TP63
4MP:00053808.9CDKN2A, HIF1A, SLC2A1, TP63, VIM
5MP:00053898.3CDKN2A, KRT14, MAPK8IP2, SDC1, TP63, VIM
6MP:00053798.2CDKN2A, HIF1A, KRT14, MAPK8IP2, SDC1, TP63
7MP:00053848.1CDKN2A, HIF1A, KRT14, SDC1, SLC2A1, TP63
8MP:00053917.5CDKN2A, HIF1A, KRT14, MAPK8IP2, TP63, VIM
9MP:00053767.2CDKN2A, HIF1A, KRT14, MAPK8IP2, SDC1, SLC2A1
10MP:00107687.2CDKN2A, HIF1A, KRT14, MAPK8IP2, SDC1, SLC2A1

Drugs & Therapeutics for Ameloblastic Carcinoma

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Ameloblastic Carcinoma

Genetic Tests for Ameloblastic Carcinoma

About this section

Anatomical Context for Ameloblastic Carcinoma

About this section

MalaCards organs/tissues related to Ameloblastic Carcinoma:

36
Smooth muscle, Lung

Publications for Ameloblastic Carcinoma

About this section

Articles related to Ameloblastic Carcinoma:

(show top 50)    (show all 115)
idTitleAuthorsYear
1
Ameloblastic Carcinoma: A Report of Three Cases. (27891485)
2016
2
Ameloblastic carcinoma of the maxilla: a report of two cases and a review of the literature. (26904494)
2016
3
Treatment of ameloblastoma and ameloblastic carcinoma with radiotherapy. (26796877)
2016
4
Immunohistochemical Expression of GLUT-1 and HIF-1I+ in Tooth Germ, Ameloblastoma, and Ameloblastic Carcinoma. (27020375)
2016
5
Ameloblastic carcinoma: a Brazilian collaborative study of 17 cases. (27195964)
2016
6
Immunohistochemical expression of K6, K8, K16, K17, K19, maspin, syndecan-1 (CD138), I+-SMA, and Ki-67 in ameloblastoma and ameloblastic carcinoma: diagnostic and prognostic correlations. (26972539)
2016
7
Ameloblastic carcinoma (secondary type) with extensive squamous differentiation areas and dedifferentiated regions. (26768075)
2016
8
Single-Fraction Helical Tomotherapy forA Ameloblastic Carcinoma. (26272005)
2015
9
Ameloblastic carcinoma of the mandible manifesting as an infected odontogenic cyst. (25574726)
2015
10
Expression of the transcription factor PITX2 in ameloblastic carcinoma. (25791324)
2015
11
Ameloblastic Carcinoma: A Case Report. (26393226)
2015
12
Primary ameloblastic carcinoma of the maxilla: A case report and literature review. (25436009)
2015
13
Spindle-cell ameloblastic carcinoma of the maxilla with adenoid cystic carcinoma-like areas: A new variant? (26549079)
2015
14
Spindle cell variant of ameloblastic carcinoma: a case report and literature review. (26238174)
2015
15
Massive Skull Base Ameloblastic Carcinoma with Intracranial Extension. (27560532)
2015
16
Ameloblastic carcinoma with features of ghost cell odontogenic carcinoma in a patient with suspected Gardner syndrome. (25434693)
2015
17
Spindle cell variant of ameloblastic carcinoma: a case report and review of literature. (25939122)
2015
18
Ameloblastic Carcinoma. (26126621)
2015
19
Immunoexpression of Ki-67, MCM2, and MCM3 in Ameloblastoma and Ameloblastic Carcinoma and Their Correlations with Clinical and Histopathological Patterns. (26823641)
2015
20
Ameloblastic carcinoma: An effort to abridge this diagnostic challenge! (26853419)
2015
21
Ameloblastic carcinoma of mandible: facts and dilemmas. (25343557)
2014
22
Identification of proteins with increased levels in ameloblastic carcinoma. (24485979)
2014
23
Prominent response with helical tomotherapy in recurrent ameloblastic carcinoma of maxillary sinus: a case report. (25027948)
2014
24
Evaluation of SOX2 as a potential marker for ameloblastic carcinoma. (24603057)
2014
25
Ameloblastic carcinoma: An analysis of 12 cases with a review of the literature. (25013517)
2014
26
Ameloblastic carcinoma: Report of a rare case. (24579073)
2014
27
Ameloblastic carcinoma of the mandible: Report of a case and review. (25364189)
2014
28
Ameloblastic carcinoma: A clinicopathologic dilemma - Report of two cases with total review of literature from 1984 to 2012. (24987603)
2014
29
Ameloblastic carcinoma developing in preexisting ameloblastoma with a mutation of the p53 gene: a case report. (24906942)
2014
30
Usefulness of (11)C-methionine positron emission tomography for detecting intracranial ameloblastic carcinoma: A case report. (25202358)
2014
31
Ameloblastic carcinoma: A case series. (25210376)
2014
32
A rare case of ameloblastic carcinoma. (25255357)
2014
33
The variability and complexity of ameloblastoma: carcinoma ex ameloblastoma or primary ameloblastic carcinoma. (22920533)
2013
34
Treatment strategy of a huge ameloblastic carcinoma. (23348302)
2013
35
Ameloblastic carcinoma, secondary type, of the mandible: a case report. (23099227)
2013
36
The use of Gamma Knife stereotactic radiosurgery in the treatment of ameloblastic carcinoma. (23726272)
2013
37
Mandibular ameloblastic carcinoma. (24034198)
2013
38
Spindle cell ameloblastic carcinoma in a labrador retriever dog. (23229541)
2013
39
Ameloblastic carcinoma of the mandible with clear cell changes: a case report. (23713037)
2013
40
Hypermethylation of p16 tumor-suppressor gene in ameloblastic carcinoma, ameloblastoma, and dental follicles. (22705216)
2013
41
Alpha smooth muscle actin expression in a case of ameloblastic carcinoma: a case report. (24422027)
2013
42
Ameloblastic carcinoma in a young patient. (24184061)
2013
43
Large ameloblastic carcinoma: A rare case with management. (24379872)
2013
44
Spindle cell variant of ameloblastic carcinoma arising from an unicystic amelobastoma: Report of a rare case. (23087740)
2012
45
Manifestation of an ameloblastic carcinoma ten years after follicular cyst enucleation in the mandibular ramus. (21741264)
2012
46
Evaluation of PKM2 and MAPK8IP2 Polymorphism in Ameloblastic Carcinoma: A Retrospective Quantitative Study. (24551779)
2012
47
Comparative evaluation of expression of proliferating cell nuclear antigen in variants of ameloblastoma and ameloblastic carcinoma. (22842243)
2012
48
Ameloblastic carcinoma, primary type: case report, immunohistochemical analysis and literature review. (22493395)
2012
49
Ameloblastic carcinoma of the maxilla with extension into the ethmoidal air cells and close proximity to the anterior skull base: a rare case presentation. (23997861)
2012
50
Ameloblastic carcinoma of the maxilla: A case report. (23205126)
2012

Variations for Ameloblastic Carcinoma

About this section

Expression for genes affiliated with Ameloblastic Carcinoma

About this section
Search GEO for disease gene expression data for Ameloblastic Carcinoma.

Pathways for genes affiliated with Ameloblastic Carcinoma

About this section

Pathways related to Ameloblastic Carcinoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.6CDKN2A, TP63
29.3HIF1A, SLC2A1
39.2CDKN2A, TP63, VIM
48.9CDKN2A, MKI67, TP63, VIM
58.9CDKN2A, HIF1A, SLC2A1

GO Terms for genes affiliated with Ameloblastic Carcinoma

About this section

Cellular components related to Ameloblastic Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein complexGO:00432348.2HIF1A, MAPK8IP2, SDC1, TP63
2cytoplasmGO:00057377.3CDKN2A, HIF1A, KRT14, MAPK8IP2, MKI67, SLC2A1

Molecular functions related to Ameloblastic Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1keratin filament bindingGO:199025410.6KRT14, VIM
2protein C-terminus bindingGO:00080229.6MKI67, SDC1, VIM
3transcription factor activity, transcription factor bindingGO:00009899.5HIF1A, TP63
4protein bindingGO:00055156.7CDKN2A, HIF1A, KRT14, MAPK8IP2, MKI67, SDC1

Sources for Ameloblastic Carcinoma

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet