MCID: AML004
MIFTS: 35

Ameloblastic Carcinoma

Categories: Rare diseases, Cancer diseases, Oral diseases

Aliases & Classifications for Ameloblastic Carcinoma

MalaCards integrated aliases for Ameloblastic Carcinoma:

Name: Ameloblastic Carcinoma 49 55 69

Characteristics:

Orphanet epidemiological data:

55
ameloblastic carcinoma
Inheritance: Not applicable; Prevalence: <1/1000000 (Worldwide); Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 55  
Rare odontological diseases


External Ids:

Orphanet 55 ORPHA314422
UMLS via Orphanet 70 C1314678
ICD10 via Orphanet 33 C41.1
UMLS 69 C1314678

Summaries for Ameloblastic Carcinoma

MalaCards based summary : Ameloblastic Carcinoma is related to ameloblastoma and spitz nevus, and has symptoms including pain An important gene associated with Ameloblastic Carcinoma is MKI67 (Marker Of Proliferation Ki-67), and among its related pathways/superpathways are MicroRNAs in cancer and DNA Damage. Affiliated tissues include smooth muscle and lung, and related phenotypes are homeostasis/metabolism and cellular

Wikipedia : 72 Ameloblastic carcinoma is a rare form of odontogenic tumor, one that develops in the jawbones from the... more...

Related Diseases for Ameloblastic Carcinoma

Diseases related to Ameloblastic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 65)
# Related Disease Score Top Affiliating Genes
1 ameloblastoma 10.4
2 spitz nevus 10.4 CDKN2A MKI67
3 squamous cell carcinoma of the larynx 10.4 CDKN2A MKI67
4 oral leukoplakia 10.4 CDKN2A MKI67
5 cervical clear cell adenocarcinoma 10.4 CDKN2A KRT14
6 odontoma 10.3 KRT14 VIM
7 malignant peritoneal mesothelioma 10.3 CDKN2A VIM
8 inverted papilloma 10.3 CDKN2A MKI67
9 sarcomatoid mesothelioma 10.3 CDKN2A VIM
10 spiradenoma 10.3 KRT14 VIM
11 pleomorphic liposarcoma 10.3 CDKN2A VIM
12 basaloid squamous cell carcinoma 10.3 CDKN2A KRT14
13 embryonal sarcoma 10.3 MKI67 VIM
14 endocervical adenocarcinoma 10.3 CDKN2A VIM
15 pre-malignant neoplasm 10.3 CDKN2A KRT14
16 malignant fibroxanthoma 10.3 MKI67 VIM
17 integumentary system benign neoplasm 10.3 KRT14 SLC2A1
18 hypohidrosis 10.2 KRT14 TP63
19 perineurioma 10.2 SLC2A1 VIM
20 intraneural perineurioma 10.2 KRT14 SLC2A1
21 limbal stem cell deficiency 10.2 KRT14 TP63
22 papillary thyroid microcarcinoma 10.2 MKI67 TP63
23 ependymoma 10.2 MKI67 VIM
24 lipoadenoma 10.2 KRT14 TP63
25 cellular schwannoma 10.2 CDKN2A SLC2A1
26 chondromyxoid fibroma 10.2 CDKN2A VIM
27 syringoma 10.2 TP63 VIM
28 in situ carcinoma 10.2 CDKN2A KRT14
29 cervical intraepithelial neoplasia 10.2 CDKN2A MKI67
30 cervix small cell carcinoma 10.2 CDKN2A MAPK8IP2
31 pinguecula 10.2 KRT14 TP63
32 dermoid cyst 10.2 TP63 VIM
33 intravascular papillary endothelial hyperplasia 10.2 HIF1A VIM
34 glomangioma 10.2 SLC2A1 VIM
35 dystonia 11, myoclonic 10.1 SLC2A1 VIM
36 cavernous hemangioma 10.1 KRT14 MKI67 VIM
37 endometrial mucinous adenocarcinoma 10.1 CDKN2A MKI67 VIM
38 chordoma 10.1 CDKN2A VIM
39 gastrointestinal stromal tumor 10.1 CDKN2A MKI67 VIM
40 spindle cell carcinoma 10.1 TP63 VIM
41 mucoepidermoid carcinoma 10.0 KRT14 MKI67 TP63
42 necrotizing sialometaplasia 10.0 CDKN2A MKI67 TP63
43 meningioma, familial 10.0 MKI67 SLC2A1 VIM
44 cervical squamous cell carcinoma 10.0 CDKN2A MKI67 TP63
45 mucinous bronchioloalveolar adenocarcinoma 10.0 CDKN2A SDC1
46 craniopharyngioma 10.0 KRT14 MKI67
47 benign breast phyllodes tumor 10.0 MKI67 TP63 VIM
48 hidradenocarcinoma 10.0 MKI67 TP63 VIM
49 polymorphous low-grade adenocarcinoma 10.0 MKI67 TP63 VIM
50 papilloma 10.0 CDKN2A KRT14 TP63

Graphical network of the top 20 diseases related to Ameloblastic Carcinoma:



Diseases related to Ameloblastic Carcinoma

Symptoms & Phenotypes for Ameloblastic Carcinoma

UMLS symptoms related to Ameloblastic Carcinoma:


pain

MGI Mouse Phenotypes related to Ameloblastic Carcinoma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.01 SDC1 SLC2A1 TP63 VIM CDKN2A HIF1A
2 cellular MP:0005384 10 TP63 VIM CDKN2A HIF1A KRT14 SDC1
3 mortality/aging MP:0010768 9.97 CDKN2A HIF1A KRT14 MAPK8IP2 SDC1 SLC2A1
4 endocrine/exocrine gland MP:0005379 9.91 CDKN2A HIF1A KRT14 MAPK8IP2 SDC1 TP63
5 neoplasm MP:0002006 9.72 CDKN2A HIF1A KRT14 SDC1 TP63
6 no phenotypic analysis MP:0003012 9.65 CDKN2A MAPK8IP2 MKI67 SLC2A1 TP63
7 reproductive system MP:0005389 9.63 CDKN2A KRT14 MAPK8IP2 SDC1 TP63 VIM
8 respiratory system MP:0005388 9.35 CDKN2A HIF1A KRT14 TP63 VIM
9 vision/eye MP:0005391 9.1 CDKN2A HIF1A KRT14 MAPK8IP2 TP63 VIM

Drugs & Therapeutics for Ameloblastic Carcinoma

Search Clinical Trials , NIH Clinical Center for Ameloblastic Carcinoma

Genetic Tests for Ameloblastic Carcinoma

Anatomical Context for Ameloblastic Carcinoma

MalaCards organs/tissues related to Ameloblastic Carcinoma:

38
Smooth Muscle, Lung

Publications for Ameloblastic Carcinoma

Articles related to Ameloblastic Carcinoma:

(show top 50) (show all 123)
# Title Authors Year
1
Reconnoitre ameloblastic carcinoma: A prognostic update. ( 29362117 )
2018
2
Ameloblastic carcinoma with metastasis to the parotid gland. ( 29124909 )
2018
3
A Rare Case Report of Spindle Cell Ameloblastic Carcinoma Involving the Mandible. ( 28274070 )
2017
4
Pattern of care and impact of prognostic factors in the outcome of ameloblastic carcinoma: a systematic review and individual patient data analysis of 199 cases. ( 28600599 )
2017
5
Cervicopectoral flap as an adequate decision for advanced ameloblastic carcinoma. ( 28984029 )
2017
6
Recurrence and cancerization of ameloblastoma: multivariate analysis of 87 recurrent craniofacial ameloblastoma to assess risk factors associated with early recurrence and secondary ameloblastic carcinoma. ( 28729769 )
2017
7
Ameloblastic Carcinoma: A Rare Malignant Tumour in Maxillofacial Region. ( 28717298 )
2017
8
Immunohistochemical Expression of GLUT-1 and HIF-1I+ in Tooth Germ, Ameloblastoma, and Ameloblastic Carcinoma. ( 27020375 )
2016
9
Ameloblastic carcinoma of the maxilla: A case report and an updated review of the literature. ( 28105148 )
2016
10
Ameloblastic carcinoma: a Brazilian collaborative study of 17 cases. ( 27195964 )
2016
11
Ameloblastic Carcinoma: A Report of Three Cases. ( 27891485 )
2016
12
Ameloblastic carcinoma of the maxilla: a report of two cases and a review of the literature. ( 26904494 )
2016
13
Immunohistochemical expression of K6, K8, K16, K17, K19, maspin, syndecan-1 (CD138), I+-SMA, and Ki-67 in ameloblastoma and ameloblastic carcinoma: diagnostic and prognostic correlations. ( 26972539 )
2016
14
Ameloblastic carcinoma (secondary type) with extensive squamous differentiation areas and dedifferentiated regions. ( 26768075 )
2016
15
Treatment of ameloblastoma and ameloblastic carcinoma with radiotherapy. ( 26796877 )
2016
16
Ameloblastic carcinoma with features of ghost cell odontogenic carcinoma in a patient with suspected Gardner syndrome. ( 25434693 )
2015
17
Spindle-cell ameloblastic carcinoma of the maxilla with adenoid cystic carcinoma-like areas: A new variant? ( 26549079 )
2015
18
Ameloblastic carcinoma of the mandible manifesting as an infected odontogenic cyst. ( 25574726 )
2015
19
Spindle cell variant of ameloblastic carcinoma: a case report and review of literature. ( 25939122 )
2015
20
Ameloblastic carcinoma: An effort to abridge this diagnostic challenge! ( 26853419 )
2015
21
Expression of the transcription factor PITX2 in ameloblastic carcinoma. ( 25791324 )
2015
22
Immunoexpression of Ki-67, MCM2, and MCM3 in Ameloblastoma and Ameloblastic Carcinoma and Their Correlations with Clinical and Histopathological Patterns. ( 26823641 )
2015
23
Single-Fraction Helical Tomotherapy forA Ameloblastic Carcinoma. ( 26272005 )
2015
24
Massive Skull Base Ameloblastic Carcinoma with Intracranial Extension. ( 27560532 )
2015
25
Spindle cell variant of ameloblastic carcinoma: a case report and literature review. ( 26238174 )
2015
26
Ameloblastic Carcinoma. ( 26126621 )
2015
27
Primary ameloblastic carcinoma of the maxilla: A case report and literature review. ( 25436009 )
2015
28
Ameloblastic Carcinoma: A Case Report. ( 26393226 )
2015
29
Ameloblastic carcinoma developing in preexisting ameloblastoma with a mutation of the p53 gene: a case report. ( 24906942 )
2014
30
Ameloblastic carcinoma: A case series. ( 25210376 )
2014
31
Ameloblastic carcinoma: An analysis of 12 cases with a review of the literature. ( 25013517 )
2014
32
Ameloblastic carcinoma of mandible: facts and dilemmas. ( 25343557 )
2014
33
Usefulness of (11)C-methionine positron emission tomography for detecting intracranial ameloblastic carcinoma: A case report. ( 25202358 )
2014
34
Ameloblastic carcinoma of the mandible: Report of a case and review. ( 25364189 )
2014
35
Ameloblastic carcinoma: A clinicopathologic dilemma - Report of two cases with total review of literature from 1984 to 2012. ( 24987603 )
2014
36
Evaluation of SOX2 as a potential marker for ameloblastic carcinoma. ( 24603057 )
2014
37
Prominent response with helical tomotherapy in recurrent ameloblastic carcinoma of maxillary sinus: a case report. ( 25027948 )
2014
38
Ameloblastic carcinoma: Report of a rare case. ( 24579073 )
2014
39
A rare case of ameloblastic carcinoma. ( 25255357 )
2014
40
Identification of proteins with increased levels in ameloblastic carcinoma. ( 24485979 )
2014
41
Treatment strategy of a huge ameloblastic carcinoma. ( 23348302 )
2013
42
Ameloblastic carcinoma of the mandible with clear cell changes: a case report. ( 23713037 )
2013
43
The variability and complexity of ameloblastoma: carcinoma ex ameloblastoma or primary ameloblastic carcinoma. ( 22920533 )
2013
44
The use of Gamma Knife stereotactic radiosurgery in the treatment of ameloblastic carcinoma. ( 23726272 )
2013
45
Large ameloblastic carcinoma: A rare case with management. ( 24379872 )
2013
46
Ameloblastic carcinoma in a young patient. ( 24184061 )
2013
47
Ameloblastic carcinoma, secondary type, of the mandible: a case report. ( 23099227 )
2013
48
Mandibular ameloblastic carcinoma. ( 24034198 )
2013
49
Alpha smooth muscle actin expression in a case of ameloblastic carcinoma: a case report. ( 24422027 )
2013
50
Hypermethylation of p16 tumor-suppressor gene in ameloblastic carcinoma, ameloblastoma, and dental follicles. ( 22705216 )
2013

Variations for Ameloblastic Carcinoma

Expression for Ameloblastic Carcinoma

Search GEO for disease gene expression data for Ameloblastic Carcinoma.

Pathways for Ameloblastic Carcinoma

Pathways related to Ameloblastic Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.97 CDKN2A TP63 VIM
2 11.73 CDKN2A MKI67 TP63 VIM
3 10.82 HIF1A SLC2A1
4 10.53 CDKN2A HIF1A SLC2A1
5
Show member pathways
10.5 CDKN2A TP63

GO Terms for Ameloblastic Carcinoma

Cellular components related to Ameloblastic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein complex GO:0043234 8.92 HIF1A MAPK8IP2 SDC1 TP63

Molecular functions related to Ameloblastic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein domain specific binding GO:0019904 9.43 HIF1A TP63 VIM
2 protein C-terminus binding GO:0008022 9.33 MKI67 SDC1 VIM
3 transcription factor activity, transcription factor binding GO:0000989 8.96 HIF1A TP63
4 keratin filament binding GO:1990254 8.62 KRT14 VIM

Sources for Ameloblastic Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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