MCID: AMP010
MIFTS: 33

Ampulla of Vater Carcinoma malady

Cancer diseases, Liver diseases, Rare diseases categories

Aliases & Classifications for Ampulla of Vater Carcinoma

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Sources:
9Disease Ontology, 11DISEASES, 47Orphanet, 60UMLS, 55SNOMED-CT, 38NCIt, 26ICD10 via Orphanet, 61UMLS via Orphanet, 25ICD10
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Ampulla of Vater Carcinoma, Aliases & Descriptions:

Name: Ampulla of Vater Carcinoma 9 11
Carcinoma of Ampulla of Vater 9 60
Ampullary Carcinoma 9 47
Carcinoma of the Ampulla of Vater 47
Tumor of the Ampulla of Vater 9
 
Neoplasm of Ampulla of Vater 60
Ampulla of Vater Neoplasm 9
Ampulla of Vater Cancer 9
Ampulloma 47


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Liver diseases


Characteristics (Orphanet epidemiological data):

47
ampullary carcinoma:
Inheritance: Not applicable; Age of onset: Adult; Age of death: adult


External Ids:

Disease Ontology9 DOID:4932, DOID:10022
NCIt38 C3908, C4443
Orphanet47 300557
ICD10 via Orphanet26 C24.1
UMLS via Orphanet61 C0262401
ICD1025 C24.1

Summaries for Ampulla of Vater Carcinoma

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Disease Ontology:9 An ampulla of vater cancer that has material basis in abnormally proliferating cells derives from epithelial cells.

MalaCards based summary: Ampulla of Vater Carcinoma, also known as carcinoma of ampulla of vater, is related to adenosquamous carcinoma and adenocarcinoma. An important gene associated with Ampulla of Vater Carcinoma is MUC2 (mucin 2, oligomeric mucus/gel-forming), and among its related pathways are NOD-like Receptor Signaling Pathways and O-linked glycosylation of mucins. The compounds cesium chloride and carbohydrates have been mentioned in the context of this disorder. Affiliated tissues include liver and lymph node.

Related Diseases for Ampulla of Vater Carcinoma

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Diseases related to Ampulla of Vater Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 61)
idRelated DiseaseScoreTop Affiliating Genes
1adenosquamous carcinoma30.6MUC5AC, MUC2
2adenocarcinoma30.5MUC2, MUC5AC, PSG2
3gallbladder cancer30.2MUC5AC, MUC2
4adenoma30.2MUC2, MUC5AC, PSG2
5cholangiocarcinoma29.9PSG2, MUC5AC, MUC2
6neuroendocrine carcinoma10.9
7large cell neuroendocrine carcinoma10.6
8gastrointestinal stromal tumor10.6
9biliary papillomatosis10.4MUC2
10small cell neuroendocrine carcinoma10.4
11acinar cell carcinoma10.4
12fibromatosis10.4
13aneurysmal bone cysts10.4
14duodenal ulcer10.4
15acalculous cholecystitis10.4
16inflammatory myofibroblastic tumor10.4
17obstructive jaundice10.4
18cholecystitis10.4
19neuroendocrine tumor10.4
20adenocarcinoid tumor10.4
21aneurysm10.4
22ampulla of vater squamous cell carcinoma10.3
23ampulla of vater adenosquamous carcinoma10.3
24ampulla of vater adenocarcinoma10.3
25pancreatitis10.3
26duodenitis10.3
27annular pancreas10.3
28microinvasive gastric cancer10.2PSG2, MUC2
29laryngeal carcinoma10.2MUC2, PSG2
30situs inversus10.1
31intrahepatic cholangiocarcinoma10.1
32spondyloarthropathy10.1
33endotheliitis10.1
34pseudomyxoma peritonei10.1MUC5AC, MUC2
35papilloma10.1MUC2, MUC5AC
36pancreatic ductal carcinoma10.1MUC5AC, MUC2
37cystadenocarcinoma10.1MUC2, MUC5AC
38bronchiolo-alveolar adenocarcinoma10.0MUC2, MUC5AC
39tubular adenocarcinoma10.0MUC5AC, MUC2
40respiratory failure10.0MUC2, MUC5AC
41factor vii deficiency10.0MUC5AC, PSG2
42barrett esophagus/esophageal adenocarcinoma10.0MUC5AC, MUC2
43pancreatic cancer10.0MUC5AC, MUC2
44adenomatous polyposis coli10.0MUC5AC, MUC2
45bladder cancer, somatic10.0PSG2, MUC2
46pulmonary disease, chronic obstructive10.0MUC5AC, MUC2
47colon adenocarcinoma9.9MUC5AC, MUC2
48cork-handlers' disease9.9PSG2, MUC5AC
49inflammatory bowel disease9.9MUC5AC, MUC2
50lung cancer9.9PSG2, MUC5AC

Graphical network of the top 20 diseases related to Ampulla of Vater Carcinoma:



Diseases related to ampulla of vater carcinoma

Symptoms for Ampulla of Vater Carcinoma

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Drugs & Therapeutics for Ampulla of Vater Carcinoma

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Drug clinical trials:

Search ClinicalTrials for Ampulla of Vater Carcinoma

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Genetic Tests for Ampulla of Vater Carcinoma

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Anatomical Context for Ampulla of Vater Carcinoma

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MalaCards organs/tissues related to Ampulla of Vater Carcinoma:

31
Liver, Lymph node

Animal Models for Ampulla of Vater Carcinoma or affiliated genes

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Publications for Ampulla of Vater Carcinoma

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Articles related to Ampulla of Vater Carcinoma:

(show all 14)
idTitleAuthorsYear
1
Ampulla of Vater carcinoma in real-world clinical practice: a case series. (25908045)
2015
2
Clinical value of serum CA19-9 as a prognostic factor for the ampulla of Vater carcinoma. (23933785)
2013
3
Proposed indications for limited resection of early ampulla of Vater carcinoma: clinico-histopathological criteria to confirm cure. (22203456)
2012
4
Mutational profiling of kinases in human tumours of pancreatic origin identifies candidate cancer genes in ductal and ampulla of vater carcinomas. (20838624)
2010
5
Significance analysis of histologic type and perineural invasion as prognostic factors after curative resection of ampulla of Vater carcinoma. (20698243)
2010
6
Spontaneous choledochoduodenal fistula after metallic biliary stent placement in a patient with ampulla of vater carcinoma. (20431778)
2009
7
Determinants of long-term survival after pancreaticoduodenectomy for ampulla of Vater carcinoma]. (20223115)
2009
8
Prognostic relevance of lymph node ratio and number of resected nodes after curative resection of ampulla of Vater carcinoma. (18712568)
2008
9
Transduodenal local resection for low-risk group ampulla of vater carcinoma. (18158802)
2007
10
Periampullary choledochoduodenal fistula associated with ampulla of Vater carcinoma. (17404887)
2007
11
Factors influencing recurrence after curative resection for ampulla of Vater carcinoma. (17326125)
2007
12
The clinicopathologic and immunohistochemical characteristics of ampulla of Vater carcinoma: the intestinal type is associated with a better prognosis. (18019683)
2007
13
Clinics in diagnostic imaging (79). Ampulla of Vater carcinoma. (12680532)
2002
14
Prognostic value of MIB-1 index and DNA ploidy in resectable ampulla of Vater carcinoma. (10203085)
1999

Variations for Ampulla of Vater Carcinoma

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Expression for genes affiliated with Ampulla of Vater Carcinoma

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Search GEO for disease gene expression data for Ampulla of Vater Carcinoma.

Pathways for genes affiliated with Ampulla of Vater Carcinoma

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Pathways related to Ampulla of Vater Carcinoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways58
Immune response IL 1 signaling pathway58
9.4MUC5AC, MUC2
2
Show member pathways
9.4MUC5AC, MUC2

Compounds for genes affiliated with Ampulla of Vater Carcinoma

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Compounds related to Ampulla of Vater Carcinoma according to GeneCards Suite gene sharing:

(show all 12)
idCompoundScoreTop Affiliating Genes
1cesium chloride43 5910.6MUC5AC, MUC2
2carbohydrates439.5MUC5AC, MUC2
3dmso439.4MUC2, MUC5AC
4pd 98,059439.4MUC5AC, MUC2
5methotrexate49 43 1211.3MUC5AC, MUC2
6sb 20358043 5910.1MUC5AC, MUC2
7hematoxylin439.1PSG2, MUC5AC, MUC2
8sialic acid439.0PSG2, MUC5AC, MUC2
95fluorouracil439.0MUC2, MUC5AC, PSG2
10paraffin439.0PSG2, MUC5AC, MUC2
11glucose438.9PSG2, MUC5AC, MUC2
12estrogen438.8MCRS1, MUC2, MUC5AC

GO Terms for genes affiliated with Ampulla of Vater Carcinoma

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Cellular components related to Ampulla of Vater Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1Golgi lumenGO:00057969.4MUC5AC, MUC2

Biological processes related to Ampulla of Vater Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1post-translational protein modificationGO:00436879.4MUC5AC, MUC2
2O-glycan processingGO:00162669.1MUC5AC, MUC2

Products for genes affiliated with Ampulla of Vater Carcinoma

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Sources for Ampulla of Vater Carcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet