MCID: AMY005
MIFTS: 23

Amyloid Neuropathy malady

Neuronal diseases category

Summaries for Amyloid Neuropathy

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32MalaCards
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MalaCards: Amyloid Neuropathy, also known as amyloid neuropathies, is related to neuropathy and polyneuropathy. An important gene associated with Amyloid Neuropathy is TTR (transthyretin), and among its related pathways are Visual phototransduction and FOXA2 and FOXA3 transcription factor networks. The compounds thioflavin t and trifluoroethanol have been mentioned in the context of this disorder. Related mouse phenotype homeostasis/metabolism.

Aliases & Classifications for Amyloid Neuropathy

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Sources:
42NIH Rare Diseases, 44Novoseek, 60UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

amyloid neuropathy 42
amyloid neuropathies 44 60
neuropathy amyloid 42


Related Diseases for Amyloid Neuropathy

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Amyloid Neuropathy:



Diseases related to amyloid neuropathy

Clinical Features for Amyloid Neuropathy

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Drugs & Therapeutics for Amyloid Neuropathy

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Amyloid Neuropathy

Drug clinical trials:

Search ClinicalTrials for Amyloid Neuropathy

Search NIH Clinical Center for Amyloid Neuropathy

Search CenterWatch for Amyloid Neuropathy

Genetic Tests for Amyloid Neuropathy

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Anatomical Context for Amyloid Neuropathy

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Animal Models for Amyloid Neuropathy or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Amyloid Neuropathy:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053768.0GSN, TTR, MPZ, APOA1

Publications for Amyloid Neuropathy

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Genetic Variations for Amyloid Neuropathy

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Expression for genes affiliated with Amyloid Neuropathy

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Amyloid Neuropathy

Search GEO for disease gene expression data for Amyloid Neuropathy.

Pathways for genes affiliated with Amyloid Neuropathy

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Sources:
53Reactome, 37NCBI BioSystems Database, 4Cell Signaling Technology
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Pathways related to Amyloid Neuropathy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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9.1TTR, APOA1
29.1TTR, APOA1
3
Hide members
9.1TTR, APOA1
49.0GSN, APOA1
58.5APOA1, TTR, GSN

Compounds for genes affiliated with Amyloid Neuropathy

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Sources:
44Novoseek, 11DrugBank, 24HMDB, 28IUPHAR, 59Tocris Bioscience
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Compounds related to Amyloid Neuropathy according to GeneCards/GeneDecks:

(show all 28)
idCompoundScoreTop Affiliating Genes
1thioflavin t449.7TTR, GSN
2trifluoroethanol44 1110.7TTR, GSN
3retinyl palmitate44 2410.5TTR, APOA1
4sodium dodecylsulfate449.5GSN, TTR
5tocopherol449.5TTR, APOA1
6mspi449.5APOA1, TTR
7guanidine44 11 2411.5TTR, APOA1
825-hydroxyvitamin d449.4TTR, APOA1
9vitamin b12449.4APOA1, TTR
10guanidine hydrochloride449.4TTR, APOA1
11uric acid44 2410.4TTR, APOA1
12carnitine449.4TTR, APOA1
13alpha tocopherol449.3TTR, APOA1
14dihydrotestosterone44 28 11 2412.3MPZ, GSN
15homocysteine44 2410.2TTR, APOA1
16cysteine449.2GSN, MPZ
17methionine449.2MPZ, TTR, GSN
18thyroxine44 2410.1TTR, APOA1
19creatinine448.9TTR, MPZ, APOA1
20fibrinogen448.9GSN, TTR, APOA1
21cholesterol44 28 11 2411.9APOA1, MPZ, TTR
22testosterone44 59 11 2411.8GSN, TTR, APOA1
23alanine448.7APOA1, TTR, GSN
24retinoic acid44 249.6GSN, TTR, APOA1
25aspartate448.4GSN, TTR, MPZ, APOA1
26glutamate448.4GSN, TTR, MPZ, APOA1
27serine448.3GSN, TTR, MPZ, APOA1
28glucose448.2GSN, TTR, APOA1

GO Terms for genes affiliated with Amyloid Neuropathy

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16Gene Ontology
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Cellular components related to Amyloid Neuropathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.5GSN, TTR, APOA1

Biological processes related to Amyloid Neuropathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1phototransduction, visible lightGO:0076039.1TTR, APOA1
2retinoid metabolic processGO:0015238.8TTR, APOA1

Products for genes affiliated with Amyloid Neuropathy

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Amyloid Neuropathy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet