Amyloidosis Cerebral malady

Genetics Home Reference: Hereditary cerebral amyloid angiopathy is a condition that can cause a progressive loss of intellectual function (dementia), stroke, and other neurological problems starting in mid-adulthood. Due to neurological decline, this condition is typically fatal in one's sixties, although there is variation depending on the severity of the signs and symptoms. Most affected individuals die within a decade after signs and symptoms first appear, although some people with the disease have survived longer.¹⁷

MalaCards: Amyloidosis Cerebral, also known as senile cerebral amyloid angiopathy, is related to cerebral amyloid angiopathy, dutch, italian, iowa, flemish, arctic variants and arteriosclerosis. An important gene associated with Amyloidosis Cerebral is APP (amyloid beta (A4) precursor protein). The drugs acetylcysteine and colchicine have been mentioned in the context of this disorder.

amyloidosis cerebral 30 senile cerebral amyloid angiopathy 30 cerebral amyloid angiopathy 30 cerebral amyloidosis 30

amyloid angiopathy 30 amyloidosis 43 caa 30

Diseases related to amyloidosis cerebral by text searches and GeneDecks gene sharing:

(show all 16)

id	Related Disease	Score	Top Affiliating Genes
1	cerebral amyloid angiopathy, dutch, italian, iowa, flemish, arctic variants	8.8
2	arteriosclerosis	8.3
3	schizophrenia	7.7
4	brain injury	7.4
5	dementia familial british	7.4
6	traumatic brain injury	7.4
7	vascular dementia	7.4
8	prostate cancer	5.4
9	prostatitis	5.4
10	spinocerebellar ataxia type 17	5.4
11	spinocerebellar ataxia type17	5.4
12	ventricular tachycardia	5.4
13	alpha thalassemia	5.4
14	bipolar disorder	5.4
15	catecholaminergic polymorphic ventricular tachycardia	5.4
16	pancreatic cancer	5.4

Approved drugs:

Drug clinical trials:

Inferred drug relations via UMLS/NDF-RT:

^43 28 acetylcysteine, colchcine, colchicine

Genes related to amyloidosis cerebral according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	APP	amyloid beta (A4) precursor protein	11.1	Disorders, Summaries