MCID: AMY082
MIFTS: 46

Amyloidosis, Familial Visceral malady

Categories: Genetic diseases, Rare diseases, Nephrological diseases, Bone diseases, Metabolic diseases, Neuronal diseases

Aliases & Classifications for Amyloidosis, Familial Visceral

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Aliases & Descriptions for Amyloidosis, Familial Visceral:

Name: Amyloidosis, Familial Visceral 51 67
Hereditary Amyloid Nephropathy 47 53 67
Familial Visceral Amyloidosis 11 69 13
Familial Amyloid Nephropathy 47 53 69
Familial Renal Amyloidosis 47 53 69
Ostertag Type Amyloidosis 11 47 69
German Type Amyloidosis 11 47 69
Hereditary Amyloidosis with Primary Renal Involement 47 53
Hereditary Renal Amyloidosis 47 53
Amyloidosis, 3 or More Types 51 12
Amyloidosis, Ostertag Type 47 53
Amyloidosis Viii 47 69
 
Amyloidosis 8 47 69
Systemic Non-Neuropathic Amyloidosis 69
Amyloidosis, Systemic Nonneuropathic 49
Systemic Nonneuropathic Amyloidosis 11
Amyloidosis Systemic Nonneuropathic 47
Amyloidosis Familial Visceral 47
Amyloidosis, Familial Renal 11
Amyloidosis Familial Renal 47
Amyloid Nephropathy 67
Amyloidosis, Renal 51
Renal Amyloidosis 49
Amyl8 69

Characteristics:

Orphanet epidemiological data:

53
hereditary amyloid nephropathy:
Inheritance: Autosomal dominant; Age of onset: All ages

HPO:

63
amyloidosis, familial visceral:
Inheritance: autosomal dominant inheritance

Classifications:



External Ids:

OMIM51 105200
Disease Ontology11 DOID:0050636
Orphanet53 ORPHA85450
ICD10 via Orphanet30 E85.0
MedGen36 C0268389
MeSH38 D028226

Summaries for Amyloidosis, Familial Visceral

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UniProtKB/Swiss-Prot:69 Amyloidosis 8: A form of hereditary generalized amyloidosis. Clinical features include extensive visceral amyloid deposits, renal amyloidosis resulting in nephrotic syndrome, arterial hypertension, hepatosplenomegaly, cholestasis, petechial skin rash. There is no involvement of the nervous system.

MalaCards based summary: Amyloidosis, Familial Visceral, also known as hereditary amyloid nephropathy, is related to apoa1-related familial visceral amyloidosis and fga-related familial visceral amyloidosis, and has symptoms including proteinuria, nephrotic syndrome and nephropathy. An important gene associated with Amyloidosis, Familial Visceral is APOA1 (Apolipoprotein A1), and among its related pathways are Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF) and Advanced glycosylation endproduct receptor signaling. Affiliated tissues include skin, kidney and bone, and related mouse phenotypes are liver/biliary system and integument.

Wikipedia:70 Familial renal amyloidosis (or familial visceral amyloidosis, or hereditary amyloid nephropathy) is a... more...

Description from OMIM:51 105200

Related Diseases for Amyloidosis, Familial Visceral

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Diseases in the Amyloidosis, Familial Visceral family:

Apoa1-Related Familial Visceral Amyloidosis Fga-Related Familial Visceral Amyloidosis
Lyz-Related Familial Visceral Amyloidosis

Diseases related to Amyloidosis, Familial Visceral via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 60)
idRelated DiseaseScoreTop Affiliating Genes
1apoa1-related familial visceral amyloidosis12.0
2fga-related familial visceral amyloidosis12.0
3lyz-related familial visceral amyloidosis12.0
4muckle-wells syndrome11.1
5adiaspiromycosis10.6LYZ, MEFV
6spasmodic dystonia10.6B2M, FGA
7tyrosinemia, type ii10.6APOA1, APOA2
8lemierre's syndrome10.5LYZ, MEFV
9abnormal threshold of rods10.5B2M, TTR
10lesion of sciatic nerve10.5B2M, TTR
11thrombotic thrombocytopenic purpura10.4B2M, LYZ
12chronic salpingitis10.4B2M, TTR
13lethal congenital contracture syndrome 110.4GSN, TTR
14autosomal recessive secondary polycythemia not associated with vhl gene10.4MEFV, TNFRSF1A
15adult-onset multiple mitochondrial dna deletion syndrome due to dguok deficiency10.4MEFV, TNFRSF1A
16mesangial proliferative glomerulonephritis10.4B2M, LYZ
17pure mitochondrial myopathy10.4MEFV, TNFRSF1A
18multiple sclerosis 510.3MEFV, TNFRSF1A
19familial cold-induced inflammatory syndrome 110.3MEFV, TNFRSF1A
20bone lymphoma10.3B2M, TTR
21blue drum syndrome10.3B2M, LYZ
22multifocal choroiditis10.3GSN, TTR
23hypotrichosis 610.2B2M, GSN, TTR
24hypervitaminosis d10.2LPA, TTR
25squamous cell papilloma10.2APOA1, GSN, TTR
26porokeratosis 3, disseminated superficial actinic10.2SAA1, TNFRSF1A
27survival motor neuron spinal muscular atrophy10.2APOA1, IAPP, TTR
28plague10.2GSN, SAA1, TTR
29amyloidosis10.1
30alzheimer disease 19, late onset10.1APOA2, LPA
31polyneuropathy10.1APOA1, APOA2, LPA
32pyloric stenosis, infantile hypertrophic, 210.1MEFV, SAA1, TNFRSF1A
33bladder diverticulum10.1APOA1, APOA2, LPA
34inflamed seborrheic keratosis10.1APOA1, APOA2, LPA
35von willebrand disease, platelet-type10.1APOA1, APOA2, LPA
36apolipoprotein c-iii deficiency10.1APOA1, APOA2, LPA
37obesity, hyperphagia, and developmental delay10.1APOA1, APOA2, LPA
38alopecia-mental retardation syndrome 310.1APOA1, GSN, LYZ, TTR
39narcolepsy 610.0APOA1, APOA2, LPA
40immunodeficiency 199.9APOA1, APOA2, LPA
41rubinstein taybi like syndrome9.9APOA1, LPA
42enteropathy-associated t-cell lymphoma9.9APP, PSEN1
43intravascular angioleiomyoma9.8APP, PSEN1
44mesenteric vascular occlusion9.7APP, SAA1
45fetal erythroblastosis9.7APP, LYZ, TNFRSF1A
46rheumatic disease9.6APP, PSEN1, TTR
47amyoplasia mandibulofacial dysostosis9.6APOA1, APOA2, FGA, GSN, LYZ, TTR
48gemistocytic astrocytoma9.6APOA1, APP, PSEN1
49chronic intestinal vascular insufficiency9.6APP, PSEN1, TTR
50obesity9.5

Graphical network of the top 20 diseases related to Amyloidosis, Familial Visceral:



Diseases related to amyloidosis, familial visceral

Symptoms for Amyloidosis, Familial Visceral

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Symptoms by clinical synopsis from OMIM:

105200

Clinical features from OMIM:

105200

Human phenotypes related to Amyloidosis, Familial Visceral:

 63 (show all 11)
id Description HPO Frequency HPO Source Accession
1 proteinuria63 HP:0000093
2 nephrotic syndrome63 HP:0000100
3 nephropathy63 HP:0000112
4 hematuria63 HP:0000790
5 hypertension63 HP:0000822
6 edema63 HP:0000969
7 skin rash63 HP:0000988
8 cholestasis63 HP:0001396
9 splenomegaly63 HP:0001744
10 hepatomegaly63 HP:0002240
11 generalized amyloid deposition63 HP:0003216

Drugs & Therapeutics for Amyloidosis, Familial Visceral

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Drugs for Amyloidosis, Familial Visceral (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Doxycyclineapproved, investigational, vet_approvedPhase 2237564-25-054671203
Synonyms:
(2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
10597-92-9
17086-28-1 (mono-hydrate)
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)
24390-14-5
41411-66-9 (6-epimer, mono-hydrochloride)
5-Hydroxy-alpha-6-deoxytetracycline
5-hydroxy-╬▒-6-deoxytetracycline
564-25-0
6-Deoxyoxytetracycline
6-Deoxytetracycline
6-alpha-Deoxy-5-oxytetracycline
6-alpha-deoxy-5-oxytetracycline
69935-17-7 (mono-hydrochloride, di-hydrate)
6alpha-Deoxy-5-oxytetracycline
6alpha-deoxy-5-oxytetracycline
6╬▒-deoxy-5-oxytetracycline
7164-70-7
7264-10-0
94088-85-4 (calcium salt (1:2))
AB08 (*Fosfatex)
AC1NQXW7
AC1NS4CW
AC1NUYS8
AC1O8PYM
Alti-Doxycycline
Anhydrous doxycycline
Apo-Doxy
Atridox
Azudoxat
BCBcMAP01_000024
BIDD:GT0146
BMY-28689
BPBio1_000951
BSPBio_000863
BSPBio_001936
BU-3839T
C06973
CHEBI:50845
CHEMBL1433
CID5281011
CID5353597
CID5463943
CID6713981
CPD001550033
D07876
DB00254
DMSC (*Fosfatex)
DOXCYCLINE ANHYDROUS
DOXY
DOXYCYCLINE CALCIUM
DOXYCYCLINE MONOHYDRATE
Deoxymykoin
DivK1c_000345
Dossiciclina
Dossiciclina [DCIT]
Doxcycline anhydrous
Doxiciclina
Doxiciclina [INN-Spanish]
Doxiciclina [Italian]
Doxitard
Doxivetin
Doxy-Caps
Doxy-Puren
Doxy-Tabs
Doxycen
Doxychel
Doxychel (TN)
Doxycin
Doxycyclin
Doxycycline (200mg/day) or Placebo
 
Doxycycline (INN)
Doxycycline (TN)
Doxycycline (anhydrous)
Doxycycline (internal use)
Doxycycline Hyclate
Doxycycline Monohydrate
Doxycycline anhydrous
Doxycycline hyclate
Doxycycline-Chinoin
Doxycyclinum
Doxycyclinum [INN-Latin]
Doxysol
Doxytec
Doxytetracycline
EINECS 209-271-1
GS-3065 (*monohydrate)
HMS2090E06
HSDB 3071
Hydramycin
IDI1_000345
Investin
Jenacyclin
KBio1_000345
KBio2_001287
KBio2_003855
KBio2_006423
KBio3_001156
KBioGR_001133
KBioSS_001287
LS-187766
LS-93868
Liviatin
Lopac0_000405
MolPort-002-507-423
Monodox
Monodox (*monohydrate)
NCGC00161602-01
NCGC00161602-03
NCGC00161602-04
NCGC00167961-01
NCGC00179395-01
NINDS_000345
NSC633557
Novo-Doxylin
Nu-Doxycycline
Oracea
Prestwick0_000852
Prestwick1_000852
Prestwick2_000852
Prestwick3_000852
Ronaxan
SAM002589932
SMP1_000107
SPBio_000246
SPBio_002784
STOCK1N-34341
Spanor
Spectrum2_000143
Spectrum3_000408
Spectrum4_000527
Spectrum5_000947
Spectrum_000807
Supracyclin
UNII-334895S862
UPCMLD-DP021
UPCMLD-DP021:001
Vibra-tabs
Vibramycin
Vibramycin (*monohydrate)
Vibramycin Novum
Vibramycine
Vibravenos
Vivox (*Hyclate)
alpha-6-Deoxy-5-hydroxytetracycline
alpha-6-Deoxyoxytetracycline
alpha-Doxycycline
doxycycline
2
Tauroursodeoxycholic acidapproved, investigationalPhase 21214605-22-212443252
Synonyms:
2-(((3-alpha,5-beta,7-beta)-3,7-Dihydroxy-24-oxocholan-24-yl) amino)ethanesulfonate
2-(((3-alpha,5-beta,7-beta)-3,7-Dihydroxy-24-oxocholan-24-yl) amino)ethanesulfonic acid
2-(((3-alpha,5-beta,7-beta)-3,7-Dihydroxy-24-oxocholan-24-yl)amino)-Ethanesulfonate
2-(((3-alpha,5-beta,7-beta)-3,7-Dihydroxy-24-oxocholan-24-yl)amino)-Ethanesulfonic acid
3a,7b-Dihydroxy-5b-cholanoyltaurine
 
N-(3-alpha,7-beta-Dihydroxy-5-beta-cholan-24-oyl)-Taurine
TUDCA
Tauroursodeoxycholate
Tauroursodeoxycholic acid
Tauroursodesoxycholic acid
UR 906
Ursodeoxycholyltaurine
3Gastrointestinal AgentsPhase 28109
4Taurochenodeoxycholic AcidPhase 211
5Cholagogues and CholereticsPhase 2127
6Antiviral AgentsPhase 29732
7Anti-Infective AgentsPhase 221402
8AntimalarialsPhase 21216
9Antiparasitic AgentsPhase 22127
10Antiprotozoal AgentsPhase 21986
11Anti-Bacterial AgentsPhase 210884

Interventional clinical trials:

idNameStatusNCT IDPhase
1Safety, Efficacy and Pharmacokinetics of Doxycycline Plus Tauroursodeoxycholic Acid in Transthyretin AmyloidosisCompletedNCT01171859Phase 2

Search NIH Clinical Center for Amyloidosis, Familial Visceral

Genetic Tests for Amyloidosis, Familial Visceral

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Anatomical Context for Amyloidosis, Familial Visceral

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MalaCards organs/tissues related to Amyloidosis, Familial Visceral:

35
Skin, Kidney, Bone

Animal Models for Amyloidosis, Familial Visceral or affiliated genes

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MGI Mouse Phenotypes related to Amyloidosis, Familial Visceral:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.7APOA1, B2M, FGA, LYZ, MEFV, TNFRSF1A
2MP:00107717.7APOA1, APP, B2M, FGA, GSN, LYZ
3MP:00053977.6APP, B2M, FGA, GSN, IAPP, LYZ
4MP:00053877.5APP, B2M, FGA, GSN, IAPP, LYZ
5MP:00053766.4APOA1, APOA2, APP, B2M, FGA, GSN

Publications for Amyloidosis, Familial Visceral

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Variations for Amyloidosis, Familial Visceral

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UniProtKB/Swiss-Prot genetic disease variations for Amyloidosis, Familial Visceral:

69
id Symbol AA change Variation ID SNP ID
1APOA1p.Gly50ArgVAR_000609rs28931574
2APOA1p.Leu84ArgVAR_000610rs121912724
3B2Mp.Asp96AsnVAR_076691rs398122820
4FGAp.Glu545ValVAR_010731rs121909612
5FGAp.Arg573LeuVAR_010732rs78506343
6LYZp.Ile74ThrVAR_004280rs121913547
7LYZp.Asp85HisVAR_004281rs121913548

Clinvar genetic disease variations for Amyloidosis, Familial Visceral:

5 (show all 16)
id Gene Variation Type Significance SNP ID Assembly Location
1LYZNM_000239.2(LYZ): c.221T> C (p.Ile74Thr)SNVPathogenicrs121913547GRCh37Chr 12, 69743972: 69743972
2LYZNM_000239.2(LYZ): c.199G> C (p.Asp67His)SNVPathogenicrs387906535GRCh37Chr 12, 69743950: 69743950
3LYZNM_000239.2(LYZ): c.244T> C (p.Trp82Arg)SNVPathogenicrs387906536GRCh37Chr 12, 69743995: 69743995
4LYZNM_000239.2(LYZ): c.223T> A (p.Phe75Ile)SNVPathogenicrs121913549GRCh37Chr 12, 69743974: 69743974
5LYZNM_000239.2(LYZ): c.244T> A (p.Trp82Arg)SNVPathogenicrs387906536GRCh37Chr 12, 69743995: 69743995
6FGANM_000508.4(FGA): c.1718G> T (p.Arg573Leu)SNVPathogenicrs78506343GRCh37Chr 4, 155506863: 155506863
7FGANM_000508.4(FGA): c.1622delT (p.Val541Alafs)deletionPathogenicrs587777761GRCh38Chr 4, 154585807: 154585807
8FGANM_000508.4(FGA): c.1634A> T (p.Glu545Val)SNVPathogenicrs121909612GRCh37Chr 4, 155506947: 155506947
9FGANM_000508.4(FGA): c.1629delG (p.Thr544Leufs)deletionPathogenicrs587777762GRCh37Chr 4, 155506952: 155506952
10FGANM_000508.4(FGA): c.991A> G (p.Thr331Ala)SNVrisk factorrs6050GRCh37Chr 4, 155507590: 155507590
11APOA1NM_000039.2(APOA1): c.251T> G (p.Leu84Arg)SNVPathogenicrs121912724GRCh37Chr 11, 116707077: 116707077
12APOA1APOA1, 12-BP DEL AND 2-BP INSindelPathogenicChr na, -1: -1
13APOA1NM_000039.2(APOA1): c.220T> C (p.Trp74Arg)SNVPathogenicrs121912726GRCh37Chr 11, 116707108: 116707108
14APOA1NM_000039.2(APOA1): c.593T> C (p.Leu198Ser)SNVPathogenicrs121912729GRCh37Chr 11, 116706735: 116706735
15APOA1NM_000039.2(APOA1): c.595G> C (p.Ala199Pro)SNVPathogenicrs121912730GRCh37Chr 11, 116706733: 116706733
16B2MNM_004048.2(B2M): c.286G> A (p.Asp96Asn)SNVPathogenicrs398122820GRCh37Chr 15, 45007839: 45007839

Expression for genes affiliated with Amyloidosis, Familial Visceral

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Search GEO for disease gene expression data for Amyloidosis, Familial Visceral.

Pathways for genes affiliated with Amyloidosis, Familial Visceral

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Pathways related to Amyloidosis, Familial Visceral according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
110.0APOA1, APOA2
29.3APP, SAA1
3
Show member pathways
9.2APOA1, SAA1, SAA2, SAA4
49.1APP, PSEN1
58.6APP, PSEN1, TNFRSF1A
6
Show member pathways
7.2APOA1, APP, B2M, FGA, GSN, IAPP
7
Show member pathways
7.2APOA1, APP, B2M, FGA, GSN, IAPP

GO Terms for genes affiliated with Amyloidosis, Familial Visceral

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Cellular components related to Amyloidosis, Familial Visceral according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1chylomicronGO:004262710.7APOA1, APOA2
2very-low-density lipoprotein particleGO:003436110.7APOA1, APOA2
3endocytic vesicle lumenGO:007168210.6APOA1, SAA1
4spherical high-density lipoprotein particleGO:003436610.6APOA1, APOA2
5ciliary rootletGO:00352539.8APP, PSEN1
6high-density lipoprotein particleGO:00343649.6APOA1, APOA2, SAA1, SAA2, SAA4
7smooth endoplasmic reticulumGO:00057909.6APP, PSEN1
8rough endoplasmic reticulumGO:00057919.5APP, FGA, PSEN1
9blood microparticleGO:00725629.4APOA1, APOA2, FGA, GSN
10cytoplasmic vesicleGO:00314108.6APOA1, APP, MEFV, PSEN1
11cell surfaceGO:00099868.4APOA1, APP, FGA, PSEN1, TNFRSF1A
12extracellular exosomeGO:00700626.6APOA1, APOA2, APP, B2M, FGA, GSN
13extracellular spaceGO:00056155.8APOA1, APOA2, APP, B2M, FGA, GSN
14extracellular regionGO:00055765.6APOA1, APOA2, APP, B2M, FGA, GSN

Biological processes related to Amyloidosis, Familial Visceral according to GeneCards Suite gene sharing:

(show all 29)
idNameGO IDScoreTop Affiliating Genes
1protein oxidationGO:001815810.6APOA1, APOA2
2regulation of intestinal cholesterol absorptionGO:003030010.6APOA1, APOA2
3negative regulation of lipase activityGO:006019210.6APOA1, APOA2
4negative regulation of very-low-density lipoprotein particle remodelingGO:001090310.6APOA1, APOA2
5positive regulation of cholesterol esterificationGO:001087310.6APOA1, APOA2
6phospholipid effluxGO:003370010.6APOA1, APOA2
7high-density lipoprotein particle assemblyGO:003438010.6APOA1, APOA2
8lipoprotein biosynthetic processGO:004215810.6APOA1, APOA2
9peptidyl-methionine modificationGO:001820610.6APOA1, APOA2
10cholesterol effluxGO:003334410.6APOA1, APOA2
11high-density lipoprotein particle clearanceGO:003438410.6APOA1, APOA2
12negative regulation of cytokine secretion involved in immune responseGO:000274010.6APOA1, APOA2
13high-density lipoprotein particle remodelingGO:003437510.5APOA1, APOA2
14phosphatidylcholine biosynthetic processGO:000665610.5APOA1, APOA2
15cholesterol transportGO:003030110.5APOA1, APOA2
16reverse cholesterol transportGO:004369110.5APOA1, APOA2
17positive chemotaxisGO:00509189.9SAA1, SAA2, SAA4
18lipoprotein metabolic processGO:00421579.8APOA1, APOA2, LPA
19amyloid fibril formationGO:19900009.8APP, GSN
20smooth endoplasmic reticulum calcium ion homeostasisGO:00515639.8APP, PSEN1
21regulation of epidermal growth factor-activated receptor activityGO:00071769.8APP, PSEN1
22acute-phase responseGO:00069539.7FGA, SAA1, SAA2, SAA4
23platelet degranulationGO:00025769.7APOA1, APP, FGA
24negative regulation of inflammatory responseGO:00507289.6APOA1, MEFV, SAA1, TNFRSF1A
25regulation of protein bindingGO:00433939.6APP, PSEN1
26retinoid metabolic processGO:00015239.6APOA1, APOA2, TTR
27cholesterol metabolic processGO:00082039.2APOA1, APOA2, APP
28innate immune responseGO:00450878.8APP, B2M, FGA, SAA1
29cellular protein metabolic processGO:00442676.4APOA1, APP, B2M, FGA, GSN, IAPP

Molecular functions related to Amyloidosis, Familial Visceral according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1high-density lipoprotein particle receptor bindingGO:007065310.6APOA1, APOA2
2lipase inhibitor activityGO:005510210.6APOA1, APOA2
3phosphatidylcholine-sterol O-acyltransferase activator activityGO:006022810.6APOA1, APOA2
4apolipoprotein receptor bindingGO:003419010.6APOA1, APOA2
5high-density lipoprotein particle bindingGO:000803510.5APOA1, APOA2
6cholesterol transporter activityGO:001712710.5APOA1, APOA2
7lipid transporter activityGO:000531910.5APOA1, APOA2
8phosphatidylcholine bindingGO:003121010.5APOA1, APOA2
9chemoattractant activityGO:00420569.8SAA1, SAA2, SAA4
10identical protein bindingGO:00428028.2APOA1, APP, B2M, IAPP, LYZ, TTR

Sources for Amyloidosis, Familial Visceral

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet