Amyloidosis, Hereditary Renal malady

MalaCards: Amyloidosis, Hereditary Renal, also known as amyloidosis, is related to transthyretin amyloidosis and hereditary amyloidosis. An important gene associated with Amyloidosis, Hereditary Renal is FGA (fibrinogen alpha chain). The drugs acetylcysteine and colchicine have been mentioned in the context of this disorder.

OMIM: 105200

amyloidosis, hereditary renal 33 amyloidosis 43

Diseases related to amyloidosis, hereditary renal by text searches and GeneDecks gene sharing:

(show top 50)    (show all 102)

id	Related Disease	Score	Top Affiliating Genes
1	transthyretin amyloidosis	9.9
2	hereditary amyloidosis	9.6
3	al amyloidosis	9.3
4	familial mediterranean fever	9.0
5	familial transthyretin amyloidosis	8.8
6	hereditary cerebral hemorrhage with amyloidosis	8.7
7	primary cutaneous amyloidosis	8.6
8	cerebral hemorrhage	8.6
9	familial visceral amyloidosis	8.4
10	rheumatoid arthritis	8.4
11	alzheimer's disease	7.9
12	lattice corneal dystrophy type ii	7.9
13	amyloidosis, secondary	7.7
14	finnish type amyloidosis	7.7
15	leptomeningeal amyloidosis	7.6
16	periodic fever	7.6
17	polyneuropathy	7.5
18	amyloidosis aa	7.3
19	amyloidosis, renal	7.3
20	neuropathy	7.1
21	amyloidosis beta2m	6.9
22	amyloidosis corneal	6.7
23	dementia	6.7
24	muckle-wells syndrome	6.7
25	multiple endocrine neoplasia	6.7
26	nephrotic syndrome	6.7
27	amyloidosis cerebral	6.4
28	amyloidosis nodular localized cutaneous	6.4
29	amyloidosis of gingiva and conjunctiva, with mental retardation	6.4
30	corneal dystrophy	6.4
31	apoa1-related familial visceral amyloidosis	6.0
32	cardiomyopathy	6.0
33	factor x deficiency	6.0
34	fga-related familial visceral amyloidosis	6.0
35	familial oculoleptomeningeal amyloidosis	6.0
36	gerstmann-straussler-scheinker disease	6.0
37	hemodialysis-related amyloidosis	6.0
38	lattice corneal dystrophy	6.0
39	lyz-related familial visceral amyloidosis	6.0
40	multiple endocrine neoplasia type 2a	6.0
41	peripheral neuropathy	6.0
42	amyloidosis bronchopulmonary	6.0
43	proteinuria	6.0
44	amyloidosis, 3 or more types	6.0
45	cerebral amyloid angiopathy	5.5
46	carpal tunnel syndrome	5.5
47	castleman's disease	5.5
48	hearing loss	5.5
49	light chain deposition disease	5.5
50	macroglobulinemia	5.5

Clinical features from OMIM: 105200

Approved drugs:

Drug clinical trials:

Inferred drug relations via UMLS/NDF-RT:

^43 28 acetylcysteine, colchcine, colchicine

Genes related to amyloidosis, hereditary renal according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	FGA	fibrinogen alpha chain	11.0	Disorders