ALS6
MCID: AMY023
MIFTS: 18

Amyotrophic Lateral Sclerosis Type 6 (ALS6) malady

Genetic diseases, Rare diseases, Neuronal diseases, Mental diseases, Nephrological diseases categories
Download this MalaCard

Summaries for Amyotrophic Lateral Sclerosis Type 6

About this section
Sources:
33MalaCards
See all sources

Fully expand this MalaCard
MalaCards: Amyotrophic Lateral Sclerosis Type 6, also known as ALS6, is related to lateral sclerosis and amyotrophic lateral sclerosis. An important gene associated with Amyotrophic Lateral Sclerosis Type 6 is FUS (fused in sarcoma).

Aliases & Classifications for Amyotrophic Lateral Sclerosis Type 6

About this section
Sources:
43NIH Rare Diseases, 22GTR
See all sources

Classifications:



Aliases & Descriptions:

amyotrophic lateral sclerosis type 6 43 22
als6 43


Related Diseases for Amyotrophic Lateral Sclerosis Type 6

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Symptoms for Amyotrophic Lateral Sclerosis Type 6

About this section

Drugs & Therapeutics for Amyotrophic Lateral Sclerosis Type 6

About this section
Sources:
42NIH Clinical Center, 6ClinicalTrials
See all sources

Drug clinical trials:

Search ClinicalTrials for Amyotrophic Lateral Sclerosis Type 6

Search NIH Clinical Center for Amyotrophic Lateral Sclerosis Type 6

Genetic Tests for Amyotrophic Lateral Sclerosis Type 6

About this section
Sources:
22GTR
See all sources

Genetic tests related to Amyotrophic Lateral Sclerosis Type 6:

id Genetic test Affiliating Genes
1 Amyotrophic Lateral Sclerosis Type 622

Anatomical Context for Amyotrophic Lateral Sclerosis Type 6

About this section

Animal Models for Amyotrophic Lateral Sclerosis Type 6 or affiliated genes

About this section

Publications for Amyotrophic Lateral Sclerosis Type 6

About this section
Sources:
52PubMed
See all sources

Articles related to Amyotrophic Lateral Sclerosis Type 6:

idTitleAuthorsYear
1
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. (19251628)
2009

Variations for Amyotrophic Lateral Sclerosis Type 6

About this section
Sources:
1 National Center for Biotechnology Information (Clinvar)
See all sources

Clinvar genetic disease variations for Amyotrophic Lateral Sclerosis Type 6:

1
id Gene Name Type Significance SNP ID Assembly Location
1FUSNM_004960.3(FUS): c.1561C> G (p.Arg521Gly)single nucleotide variantPathogenicrs121909668GRCh37Chr 16, 31202739: 31202739
2FUSNM_004960.3(FUS): c.1553G> A (p.Arg518Lys)single nucleotide variantPathogenicrs121909669GRCh37Chr 16, 31202731: 31202731
3FUSNM_004960.3(FUS): c.1561C> T (p.Arg521Cys)single nucleotide variantPathogenicrs121909668GRCh37Chr 16, 31202739: 31202739
4FUSNM_004960.3(FUS): c.1562G> A (p.Arg521His)single nucleotide variantPathogenicrs121909671GRCh37Chr 16, 31202740: 31202740
5FUSNM_004960.3(FUS): c.1520G> A (p.Gly507Asp)single nucleotide variantPathogenicrs267606831GRCh37Chr 16, 31202410: 31202410
6FUSNM_004960.3(FUS): c.646C> T (p.Arg216Cys)single nucleotide variantPathogenicrs267606832GRCh37Chr 16, 31196382: 31196382
7FUSNM_004960.3(FUS): c.1570A> T (p.Arg524Trp)single nucleotide variantPathogenicrs267606833GRCh37Chr 16, 31202748: 31202748
8FUSNM_004960.3(FUS): c.1483C> T (p.Arg495Ter)single nucleotide variantPathogenicrs387906627GRCh37Chr 16, 31202373: 31202373
9FUSNM_004960.3(FUS): c.616G> A (p.Gly206Ser)single nucleotide variantPathogenicrs387906628GRCh37Chr 16, 31196352: 31196352

Expression for genes affiliated with Amyotrophic Lateral Sclerosis Type 6

About this section
Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Amyotrophic Lateral Sclerosis Type 6

Search GEO for disease gene expression data for Amyotrophic Lateral Sclerosis Type 6.

Pathways for genes affiliated with Amyotrophic Lateral Sclerosis Type 6

About this section

Compounds for genes affiliated with Amyotrophic Lateral Sclerosis Type 6

About this section

GO Terms for genes affiliated with Amyotrophic Lateral Sclerosis Type 6

About this section

Products for genes affiliated with Amyotrophic Lateral Sclerosis Type 6

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Amyotrophic Lateral Sclerosis Type 6

About this section
4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet