ALS6
MCID: AMY023
MIFTS: 18

Amyotrophic Lateral Sclerosis Type 6 (ALS6) malady

Genetic diseases, Rare diseases, Neuronal diseases, Mental diseases, Nephrological diseases categories

Summaries for Amyotrophic Lateral Sclerosis Type 6

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34MalaCards
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MalaCards: Amyotrophic Lateral Sclerosis Type 6, also known as ALS6, is related to lateral sclerosis and amyotrophic lateral sclerosis. An important gene associated with Amyotrophic Lateral Sclerosis Type 6 is FUS (fused in sarcoma).

Aliases & Classifications for Amyotrophic Lateral Sclerosis Type 6

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Sources:
44NIH Rare Diseases, 23GTR
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Classifications:



Aliases & Descriptions:

amyotrophic lateral sclerosis type 6 44 23
als6 44


Related Diseases for Amyotrophic Lateral Sclerosis Type 6

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Sources:
18GeneCards, 19GeneDecks
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Symptoms for Amyotrophic Lateral Sclerosis Type 6

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Drugs & Therapeutics for Amyotrophic Lateral Sclerosis Type 6

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Amyotrophic Lateral Sclerosis Type 6

Drug clinical trials:

Search ClinicalTrials for Amyotrophic Lateral Sclerosis Type 6

Search NIH Clinical Center for Amyotrophic Lateral Sclerosis Type 6

Search CenterWatch for Amyotrophic Lateral Sclerosis Type 6

Genetic Tests for Amyotrophic Lateral Sclerosis Type 6

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Sources:
23GTR
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Genetic tests related to Amyotrophic Lateral Sclerosis Type 6:

id Genetic test Affiliating Genes
1 Amyotrophic Lateral Sclerosis Type 623

Anatomical Context for Amyotrophic Lateral Sclerosis Type 6

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Animal Models for Amyotrophic Lateral Sclerosis Type 6 or affiliated genes

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Publications for Amyotrophic Lateral Sclerosis Type 6

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53PubMed
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Articles related to Amyotrophic Lateral Sclerosis Type 6:

idTitleAuthorsYear
1
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. (19251628)
2009

Variations for Amyotrophic Lateral Sclerosis Type 6

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1 National Center for Biotechnology Information (Clinvar)
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Clinvar genetic disease variations for Amyotrophic Lateral Sclerosis Type 6:

1
id Gene Name Type Significance SNP ID Assembly Location
1FUSNM_004960.3(FUS): c.1561C> G (p.Arg521Gly)single nucleotide variantPathogenicrs121909668GRCh37Chr 16, 31202739: 31202739
2FUSNM_004960.3(FUS): c.1553G> A (p.Arg518Lys)single nucleotide variantPathogenicrs121909669GRCh37Chr 16, 31202731: 31202731
3FUSNM_004960.3(FUS): c.1561C> T (p.Arg521Cys)single nucleotide variantPathogenicrs121909668GRCh37Chr 16, 31202739: 31202739
4FUSNM_004960.3(FUS): c.1562G> A (p.Arg521His)single nucleotide variantPathogenicrs121909671GRCh37Chr 16, 31202740: 31202740
5FUSNM_004960.3(FUS): c.1520G> A (p.Gly507Asp)single nucleotide variantPathogenicrs267606831GRCh37Chr 16, 31202410: 31202410
6FUSNM_004960.3(FUS): c.646C> T (p.Arg216Cys)single nucleotide variantPathogenicrs267606832GRCh37Chr 16, 31196382: 31196382
7FUSNM_004960.3(FUS): c.1570A> T (p.Arg524Trp)single nucleotide variantPathogenicrs267606833GRCh37Chr 16, 31202748: 31202748
8FUSNM_004960.3(FUS): c.1483C> T (p.Arg495Ter)single nucleotide variantPathogenicrs387906627GRCh37Chr 16, 31202373: 31202373
9FUSNM_004960.3(FUS): c.616G> A (p.Gly206Ser)single nucleotide variantPathogenicrs387906628GRCh37Chr 16, 31196352: 31196352

Expression for genes affiliated with Amyotrophic Lateral Sclerosis Type 6

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Amyotrophic Lateral Sclerosis Type 6

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Pathways for genes affiliated with Amyotrophic Lateral Sclerosis Type 6

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Compounds for genes affiliated with Amyotrophic Lateral Sclerosis Type 6

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GO Terms for genes affiliated with Amyotrophic Lateral Sclerosis Type 6

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Products for genes affiliated with Amyotrophic Lateral Sclerosis Type 6

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Amyotrophic Lateral Sclerosis Type 6

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet