MCID: ANP006
MIFTS: 41

Anaplastic Ependymoma malady

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Anaplastic Ependymoma

Aliases & Descriptions for Anaplastic Ependymoma:

Name: Anaplastic Ependymoma 50 56 52 69
High-Grade Ependymoma 56

Characteristics:

Orphanet epidemiological data:

56
anaplastic ependymoma
Inheritance: Not applicable; Age of onset: Adolescent,Adult,Childhood;

Classifications:

Orphanet: 56  
Rare neurological diseases


External Ids:

Orphanet 56 ORPHA251646
UMLS via Orphanet 70 C0280788

Summaries for Anaplastic Ependymoma

NIH Rare Diseases : 50 an ependymoma is a tumor that forms when cells in the central nervous system (including the brain and spinal cord) begin to multiple rapidly.  an anaplastic ependymoma is one in which the cells are significantly unusual and grow very quickly.  ependymomas can occur at any age; when they occur in children, they are more frequently located in the brain, whereas they are more often found in the spinal cord of affected adults.  symptoms of an ependymoma depend on the age of the patient and the size and location of the tumor.  though the exact cause of ependymoma is not yet known, it is thought that changes (mutations) in certain genes allow the cells to begin growing quickly.  treatment for ependymoma begins with surgery to remove as much of the tumor as possible, and may include other therapies as well.  of all individuals diagnosed with an ependymoma, approximately half are alive five years after their initial diagnosis. last updated: 3/27/2012

MalaCards based summary : Anaplastic Ependymoma, also known as high-grade ependymoma, is related to myxopapillary ependymoma and subependymoma, and has symptoms including headache, nausea and seizures. An important gene associated with Anaplastic Ependymoma is MUC1 (Mucin 1, Cell Surface Associated), and among its related pathways/superpathways are Cytoskeletal Signaling and MicroRNAs in cancer. The drugs Donepezil and Fentanyl have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and bone, and related phenotype is behavior/neurological.

Related Diseases for Anaplastic Ependymoma

Diseases related to Anaplastic Ependymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 214)
id Related Disease Score Top Affiliating Genes
1 myxopapillary ependymoma 29.3 GFAP NF2 SYP VIM
2 subependymoma 11.0
3 malignant ependymoma 11.0
4 malignant adult ependymoma 11.0
5 ependymoma 10.7
6 lucey-driscoll syndrome 10.3 MUC1 S100B
7 secondary pulmonary hemosiderosis 10.3 MUC1 S100B
8 invasive mole 10.3 MUC1 S100B
9 pemphigus vegetans 10.3 MUC1 S100B
10 skeletal-extraskeletal angiomatosis 10.3 MUC1 SYP
11 endocardium cancer 10.3 MUC1 S100B
12 prolactin producing pituitary tumor 10.3 MUC1 SYP
13 precursor t-lymphoblastic lymphoma/leukemia 10.3 MUC1 S100B
14 hypoparathyroidism-intellectual disability-dysmorphism syndrome 10.2 S100B SYP
15 marfanoid hypermobility syndrome 10.2 MUC1 VIM
16 tanycytic ependymoma 10.2 MUC1 VIM
17 movement disease 10.2 S100B SYP
18 bladder adenocarcinoma 10.2 MUC1 VIM
19 nipple neoplasm 10.2 MUC1 SYP
20 benign schwannoma 10.2 S100B VIM
21 avian influenza 10.2 MUC1 VIM
22 early-onset parkinson disease 10.2 S100B SYP
23 bone deterioration disease 10.2 S100B SYP
24 testicular granulosa cell tumor 10.2 MUC1 VIM
25 petrous apex meningioma 10.2 MUC1 VIM
26 pelvic inflammatory disease 10.2 MUC1 SYP
27 thymoma 10.2 MUC1 SYP
28 vulvar angiokeratoma 10.2 MUC1 VIM
29 lymphangiosarcoma 10.2 MUC1 VIM
30 vagina leiomyosarcoma 10.2 GFAP MUC1
31 cavernous sinus meningioma 10.2 S100B VIM
32 bone marrow cancer 10.2 MUC1 SYP
33 adult central nervous system primitive neuroectodermal neoplasm 10.2 SYP VIM
34 progeria 10.2 MUC1 VIM
35 pulmonary neuroendocrine tumor 10.2 MUC1 S100B
36 anal gland neoplasm 10.2 MUC1 VIM
37 tabes dorsalis 10.2 MUC1 SYP
38 appendix mucinous cystadenocarcinoma 10.2 MUC1 VIM
39 dyslexia 10.2 S100B VIM
40 strabismus 10.2 S100B SYP
41 diabetes hypogonadism deafness mental retardation 10.2 GFAP SYP
42 papillary tumor of the pineal region 10.2 GFAP SYP
43 brain stem ependymoma 10.2 GFAP SYP
44 episodic ataxia 10.2 MDM2 MUC1
45 stomach diverticulosis 10.2 S100B VIM
46 mesenchymoma 10.2 MUC1 VIM
47 intrahepatic bile duct adenoma 10.2 GFAP SYP
48 pilocytic astrocytoma of cerebellum 10.2 GFAP SYP
49 uterine corpus leiomyomatosis 10.2 MUC1 S100B
50 children's interstitial lung disease 10.2 GFAP SYP

Graphical network of the top 20 diseases related to Anaplastic Ependymoma:



Diseases related to Anaplastic Ependymoma

Symptoms & Phenotypes for Anaplastic Ependymoma

UMLS symptoms related to Anaplastic Ependymoma:


headache, nausea, seizures, vomiting

MGI Mouse Phenotypes related to Anaplastic Ependymoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.17 NF2 PTEN S100B SYP VIM GFAP

Drugs & Therapeutics for Anaplastic Ependymoma

Drugs for Anaplastic Ependymoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 237)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Donepezil Approved Phase 3,Phase 2 120014-06-4 3152
2
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
3
Dopamine Approved Phase 3 51-61-6, 62-31-7 681
4
Histamine Approved, Investigational Phase 3 75614-87-8, 51-45-6 774
5
Cyproheptadine Approved Phase 3 129-03-3 2913
6
Methylphenidate Approved, Investigational Phase 3 113-45-1 4158
7 Dermatologic Agents Phase 3,Phase 1,Phase 2
8 Central Nervous System Depressants Phase 3,Phase 1,Phase 2
9 pancreatic polypeptide Phase 3,Phase 1
10 Analgesics Phase 3,Phase 2,Phase 1
11 Cholinergic Agents Phase 3,Phase 2
12 Adjuvants, Anesthesia Phase 3
13 Cholinesterase Inhibitors Phase 3,Phase 2
14 Narcotics Phase 3
15 Gastrointestinal Agents Phase 3,Phase 2,Phase 1
16 Neurotransmitter Agents Phase 3,Phase 2
17 Nootropic Agents Phase 3,Phase 2
18 Analgesics, Opioid Phase 3
19 Anesthetics Phase 3,Phase 1
20 Anesthetics, General Phase 3
21 Anesthetics, Intravenous Phase 3
22 Peripheral Nervous System Agents Phase 3,Phase 2,Phase 1
23 Liver Extracts Phase 3,Phase 2,Phase 1
24 Central Nervous System Stimulants Phase 3,Phase 2
25 Dopamine Agents Phase 3
26
Histamine Phosphate Phase 3 51-74-1 65513
27
Serotonin Phase 3 50-67-9 5202
28 Serotonin Agents Phase 3
29 Serotonin Antagonists Phase 3
30 Neurotransmitter Uptake Inhibitors Phase 3
31 Histamine Antagonists Phase 3
32 Histamine H1 Antagonists Phase 3
33 Dexmethylphenidate Hydrochloride Phase 3
34 Dopamine Uptake Inhibitors Phase 3
35 Anti-Allergic Agents Phase 3
36 Antipruritics Phase 3
37 Cola Nutraceutical Phase 3,Phase 1
38
Ethanol Approved Phase 1, Phase 2 64-17-5 702
39
Aminolevulinic acid Approved Phase 2 106-60-5 137
40
Dacarbazine Approved, Investigational Phase 2,Phase 1 4342-03-4 5351166
41
Temozolomide Approved, Investigational Phase 2,Phase 1 85622-93-1 5394
42
Carmustine Approved Phase 1, Phase 2 154-93-8 2578
43
Doxorubicin Approved, Investigational Phase 2 23214-92-8 31703
44
Vincristine Approved, Investigational Phase 2,Phase 1 2068-78-2, 57-22-7 5978
45
Paclitaxel Approved, Vet_approved Phase 2,Phase 1 33069-62-4 36314
46
Etoposide Approved Phase 2,Phase 1 33419-42-0 36462
47
Cisplatin Approved Phase 2,Phase 1 15663-27-1 84093 441203 2767
48
Topotecan Approved, Investigational Phase 2 119413-54-6, 123948-87-8 60700
49
Methotrexate Approved Phase 2 1959-05-2, 59-05-2 126941
50
Irinotecan Approved, Investigational Phase 2 97682-44-5, 100286-90-6 60838

Interventional clinical trials:

(show top 50) (show all 106)
id Name Status NCT ID Phase
1 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3
2 Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors Completed NCT00369785 Phase 3
3 Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors Terminated NCT00031798 Phase 3
4 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3
5 Phase I/II Trial of Safety and Anti-tumor Efficacy of AXL1717(Picropodophyllin) in the Treatment of Recurrent Malignant Astrocytomas Unknown status NCT01721577 Phase 1, Phase 2
6 Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma Unknown status NCT00826241 Phase 2
7 Carmustine Followed By Surgery in Treating Patients With Recurrent Supratentorial Malignant Glioma or Metastatic Brain Neoplasm Unknown status NCT00009854 Phase 1, Phase 2
8 Veliparib and Temozolomide in Treating Patients With Recurrent Glioblastoma Unknown status NCT01026493 Phase 1, Phase 2
9 A Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Malignant Glial Tumors of the Brain Unknown status NCT01403311 Phase 2
10 Etoposide Plus Cisplatin in Treating Patients With Recurrent Ependymomas Completed NCT00002876 Phase 2
11 Combination Chemotherapy Plus Radiation Therapy in Treating Adult Patients With Brain Cancer Completed NCT00003309 Phase 2
12 Poly-ICLC in Treating Patients With Recurrent or Progressive Anaplastic Glioma Completed NCT00058123 Phase 2
13 Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors Completed NCT01836549 Phase 2
14 Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer Completed NCT00492089 Phase 2
15 Thiotepa Followed by Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Malignant Glioma Completed NCT00008008 Phase 2
16 Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma Completed NCT00006258 Phase 2
17 Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors Completed NCT00002608 Phase 2
18 Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Cancers Completed NCT00002752 Phase 1, Phase 2
19 Armodafinil in Treating Fatigue Caused By Radiation Therapy in Patients With Primary Brain Tumors Completed NCT01032200 Phase 2
20 Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging in Evaluating Patients Who Are Undergoing Treatment for Gliomas Completed NCT00274755 Phase 2
21 Tamoxifen, Carboplatin, and Topotecan in Treating Patients With CNS Metastases or Recurrent Brain or Spinal Cord Tumors Completed NCT00541138 Phase 2
22 Temozolomide in Treating Patients With Recurrent Glioblastoma Multiforme or Other Malignant Glioma Completed NCT00498927 Phase 2
23 Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor Completed NCT00070161 Phase 2
24 Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and/or Radiation Therapy For Primary Brain Tumors Completed NCT00629889 Phase 2
25 Chemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain Cancer Completed NCT00014573 Phase 2
26 Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary Brain Tumors Completed NCT00003478 Phase 1, Phase 2
27 Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) With Bevacizumab and Irinotecan for Malignant Glioma Completed NCT00352521 Phase 2
28 Sunitinib Malate in Treating Younger Patients With Recurrent, Refractory, or Progressive Malignant Glioma or Ependymoma Completed NCT01462695 Phase 2
29 Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma Completed NCT00381797 Phase 2
30 Bevacizumab and Lapatinib in Children With Recurrent or Refractory Ependymoma Completed NCT00883688 Phase 2
31 Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors Completed NCT00095940 Phase 1, Phase 2
32 Carboplatin and Bevacizumab for Recurrent Ependymoma Recruiting NCT01295944 Phase 2
33 Everolimus for Children With Recurrent or Progressive Ependymoma Recruiting NCT02155920 Phase 2
34 Efficacy of Hypofractionated XRT w/Bev. + Temozolomide for Recurrent Gliomas Active, not recruiting NCT01478321 Phase 2
35 Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma Active, not recruiting NCT00027846 Phase 2
36 Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer Active, not recruiting NCT00445965 Phase 2
37 Crizotinib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma Active, not recruiting NCT00939770 Phase 1, Phase 2
38 Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas Active, not recruiting NCT01125046 Phase 2
39 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2
40 Phase II Pediatric Study With Dabrafenib in HGG Patients Not yet recruiting NCT02684058 Phase 2
41 Antineoplaston Therapy in Treating Patients With Ependymoma Terminated NCT00003479 Phase 2
42 Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Glioma Terminated NCT01095094 Phase 2
43 Photodynamic Therapy in the Treatment of Malignant Intracranial Tumors Withdrawn NCT00243490 Phase 2
44 Functional Magnetic Resonance Imaging and 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Treating Patients With Newly Diagnosed Brain Tumors Withdrawn NCT00005083 Phase 2
45 Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors Unknown status NCT00002647 Phase 1
46 Enzastaurin and Temozolomide in Treating Patients With Primary Gliomas Unknown status NCT00516607 Phase 1
47 Lonafarnib and Temozolomide in Treating Patients With Recurrent Primary Supratentorial Gliomas Unknown status NCT00083096 Phase 1
48 Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Gluco Completed NCT01082926 Phase 1
49 Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction Completed NCT00030498 Phase 1
50 Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors Completed NCT01131234 Phase 1

Search NIH Clinical Center for Anaplastic Ependymoma

Genetic Tests for Anaplastic Ependymoma

Anatomical Context for Anaplastic Ependymoma

MalaCards organs/tissues related to Anaplastic Ependymoma:

39
Spinal Cord, Brain, Bone

Publications for Anaplastic Ependymoma

Articles related to Anaplastic Ependymoma:

(show top 50) (show all 86)
id Title Authors Year
1
Magnetic resonance imaging findings of extraventricular anaplastic ependymoma: A report of 11 cases. ( 27602137 )
2016
2
Supratentorial extraventricular WHO grade III (anaplastic) ependymoma 17 years after total removal of WHO grade II ependymoma of the fourth ventricle. ( 27215793 )
2016
3
Angiocentric glioma transformed into anaplastic ependymoma: Review of the evidence for malignant potential. ( 27742374 )
2016
4
Brain Tumor in an In Vitro Fertilization-Facilitated Pregnancy: Fourth Ventricle Anaplastic Ependymoma in the Second Trimester. ( 27330925 )
2016
5
Pure extra-axial supratentorial anaplastic ependymoma with no cortical attachment: A rare case. ( 26954823 )
2016
6
Radiation-induced anaplastic ependymoma mimicking a skull base meningioma: A case report. ( 26893630 )
2016
7
Re-irradiation of recurrent anaplastic ependymoma using radiosurgery or fractionated stereotactic radiotherapy. ( 26682738 )
2016
8
Erratum to: Re-irradiation of recurrent anaplastic ependymoma using radiosurgery or fractionated stereotactic radiotherapy. ( 26820979 )
2016
9
An extraneural primary anaplastic ependymoma at the subcutaneous inguinal region: Report of a rare case. ( 26549094 )
2015
10
Paediatric Intracranial Anaplastic Ependymoma: The Role of Multiple Surgical Resections for Disease Relapse in Maintaining Quality of Life and Prolonged Survival. ( 25871983 )
2015
11
Temozolomide Treatment for Pediatric Refractory Anaplastic Ependymoma With Low MGMT Protein Expression. ( 26305586 )
2015
12
Role of Evaluating MGMT Status and 1p36 Deletion in Radiosurgery-Induced Anaplastic Ependymoma That Rapidly and Completely Resolved by Temozolomide Alone: Case Report and Review of the Literature. ( 26251808 )
2015
13
Anaplastic Ependymoma in a Child With Sickle Cell Anemia: A Case Report Highlighting Treatment Challenges for Young Children With Central Nervous System Tumors and Underlying Vasculopathy. ( 26488903 )
2015
14
An 11 Year Old Child with a Right Parieto-Occipital Lesion. Anaplastic Ependymoma (WHO Grade III) with Granular Cell Features. ( 26086056 )
2015
15
Supratentorial extraventricular anaplastic ependymoma with extracranial metastasis. ( 25455735 )
2015
16
Anaplastic ependymoma of spinal cord presented with lower back pain. ( 25843250 )
2015
17
Treatment of Ovarian Anaplastic Ependymoma by an Aromatase Inhibitor. ( 24413241 )
2014
18
Anaplastic ependymoma of the third ventricle. ( 24643478 )
2014
19
Ectopic cortical anaplastic ependymoma: an unusual case report and literature review. ( 25051164 )
2014
20
Supratentorial Extraventricular Anaplastic Ependymoma Presenting with Repeated Intratumoral Hemorrhage. ( 25408930 )
2014
21
Supratentorial extraventricular anaplastic ependymoma in a child. ( 24623545 )
2014
22
Extra and intramedullary anaplastic ependymoma in thoracic spinal cord. ( 24757483 )
2013
23
Anaplastic ependymoma with holocordal and intracranial meningeal carcinomatosis and holospinal bone metastases. ( 23422903 )
2013
24
Supratentorial extraventricular anaplastic ependymoma in an adult with repeated intratumoral hemorrhage. ( 23546851 )
2013
25
Cortical anaplastic ependymoma with significant desmoplasia: a case report and literature review. ( 24455359 )
2013
26
Anaplastic ependymoma with ependymoblastic multilayered rosettes. ( 23791209 )
2013
27
A headache presenting in the emergency room, a clinical manifestation of an unfortunate diagnosis (grade III left frontal anaplastic ependymoma with 1p deletion). ( 23912654 )
2013
28
Cisplatin and temozolomide combination in the treatment of supratentorial anaplastic ependymoma. ( 24192541 )
2013
29
Radiation-induced anaplastic ependymoma with a remarkable clinical response to temozolomide: a case report. ( 23163298 )
2013
30
Supratentorial gross-totally resected non-anaplastic ependymoma: population based patterns of care and outcomes analysis. ( 24085643 )
2013
31
Metronomic cyclophosphamide with cisplatin and bevacizumab: a new chemotherapeutic regimen for refractory anaplastic ependymoma. ( 23155280 )
2012
32
Supratentorial extra-axial anaplastic ependymoma mimicking a meningioma. ( 22406799 )
2012
33
Tandem high-dose chemotherapy and autologous stem cell transplantation for anaplastic ependymoma in children younger than 3 years of age. ( 22081297 )
2012
34
Cystic with mural nodule: Unusual radiological presentation of supratentorial anaplastic ependymoma. ( 23248684 )
2012
35
Sacrococcygeal myxopapillary ependymoma with anaplastic ependymoma component in an infant. ( 23560014 )
2012
36
An anaplastic ependymoma presenting as an intrinsic brainstem glioma. ( 22406810 )
2012
37
Purely cortical anaplastic ependymoma. ( 23119204 )
2012
38
Anaplastic ependymoma simulating glioblastoma in the cerebrum of an adult. ( 21833575 )
2012
39
Extraventricular anaplastic ependymoma with metastasis to scalp and neck. ( 21222217 )
2011
40
Spinal intradural, extramedullary anaplastic ependymoma with an extradural component: Case report and review of the literature. ( 21918734 )
2011
41
Metachronous occurrence of a temporal ganglioglioma and a bifrontal anaplastic ependymoma: coincidence or an explainable pathological curiosity? ( 21501061 )
2011
42
Isolated extracranial recurrence of anaplastic ependymoma. ( 20830772 )
2011
43
Anaplastic ependymoma with sclerotic bone metastases. ( 20979177 )
2010
44
Huge supratentorial extraventricular anaplastic ependymoma presenting with massive calcification--case report. ( 20185883 )
2010
45
Supratentorial extraventricular anaplastic ependymoma in a 10-year-old girl. ( 21555909 )
2010
46
Recurrent posterior fossa anaplastic ependymoma with prominent chondroid metaplasia: a case report and review of literature. ( 21045418 )
2010
47
Dissemination limits the survival of patients with anaplastic ependymoma after extensive surgical resection, meticulous follow up, and intensive treatment for recurrence. ( 20186454 )
2010
48
Metastasizing anaplastic ependymoma in an adult. Chromosomal imbalances, metabolic and gene expression profiles. ( 19309408 )
2009
49
A case of an anaplastic ependymoma with gliosarcomatous components. ( 19408092 )
2009
50
Divergent ependymal tumor (ependymoblastoma/anaplastic ependymoma) of the posterior fossa: an uncommon case observed in a child. ( 18827270 )
2008

Variations for Anaplastic Ependymoma

Expression for Anaplastic Ependymoma

Search GEO for disease gene expression data for Anaplastic Ependymoma.

Pathways for Anaplastic Ependymoma

Pathways related to Anaplastic Ependymoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 12.06 MUC1 NF2 VIM
2 12.02 MDM2 PTEN VIM
3 11.77 GFAP NF2 S100B SYP
4 11.48 MDM2 NF2 PTEN
5
Show member pathways
11.37 GFAP MDM2 S100B
6 10.98 MDM2 PTEN
7 10.83 GFAP S100B SYP VIM

GO Terms for Anaplastic Ependymoma

Cellular components related to Anaplastic Ependymoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 neuron projection GO:0043005 8.92 NF2 PTEN SYP VIM

Biological processes related to Anaplastic Ependymoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 learning or memory GO:0007611 9.32 PTEN S100B
2 long-term synaptic potentiation GO:0060291 9.26 PTEN S100B
3 cellular response to organic substance GO:0071310 9.16 MDM2 SYP
4 regulation of neuronal synaptic plasticity GO:0048168 8.96 S100B SYP
5 cellular response to hypoxia GO:0071456 8.8 MDM2 PTEN S100B

Molecular functions related to Anaplastic Ependymoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.1 GFAP MDM2 PTEN S100B SYP VIM
2 scaffold protein binding GO:0097110 8.96 MDM2 VIM

Sources for Anaplastic Ependymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
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42 MeSH
43 MESH via Orphanet
44 MGI
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48 NDF-RT
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54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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