MCID: ANP006
MIFTS: 42

Anaplastic Ependymoma

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Anaplastic Ependymoma

MalaCards integrated aliases for Anaplastic Ependymoma:

Name: Anaplastic Ependymoma 50 56 52 69
High-Grade Ependymoma 56

Characteristics:

Orphanet epidemiological data:

56
anaplastic ependymoma
Inheritance: Not applicable; Age of onset: Adolescent,Adult,Childhood;

Classifications:

Orphanet: 56  
Rare neurological diseases


External Ids:

Orphanet 56 ORPHA251646
UMLS via Orphanet 70 C0280788

Summaries for Anaplastic Ependymoma

NIH Rare Diseases : 50 an ependymoma is a tumor that forms when cells in the central nervous system (including the brain and spinal cord) begin to multiple rapidly.  an anaplastic ependymoma is one in which the cells are significantly unusual and grow very quickly.  ependymomas can occur at any age; when they occur in children, they are more frequently located in the brain, whereas they are more often found in the spinal cord of affected adults.  symptoms of an ependymoma depend on the age of the patient and the size and location of the tumor.  though the exact cause of ependymoma is not yet known, it is thought that changes (mutations) in certain genes allow the cells to begin growing quickly.  treatment for ependymoma begins with surgery to remove as much of the tumor as possible, and may include other therapies as well.  of all individuals diagnosed with an ependymoma, approximately half are alive five years after their initial diagnosis. last updated: 3/27/2012

MalaCards based summary : Anaplastic Ependymoma, also known as high-grade ependymoma, is related to ganglioglioma and ependymoma, and has symptoms including headache, nausea and seizures. An important gene associated with Anaplastic Ependymoma is MUC1 (Mucin 1, Cell Surface Associated), and among its related pathways/superpathways are Cytoskeletal Signaling and MicroRNAs in cancer. The drugs Fentanyl and Donepezil have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and bone, and related phenotype is behavior/neurological.

Related Diseases for Anaplastic Ependymoma

Diseases related to Anaplastic Ependymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 228)
id Related Disease Score Top Affiliating Genes
1 ganglioglioma 29.2 GFAP MUC1 S100B VIM
2 ependymoma 11.5
3 subependymoma 11.0
4 logopenic progressive aphasia 10.7 MUC1 S100B
5 heiner syndrome 10.7 MUC1 S100B
6 dedifferentiated liposarcoma 10.7 MUC1 S100B
7 simple cryoglobulinemia 10.7 MUC1 S100B
8 enteric pattern testicular yolk sac tumor 10.7 MUC1 S100B
9 gastric papillary adenocarcinoma 10.6 MUC1 S100B
10 situs inversus totalis with cystic dysplasia of kidneys and pancreas 10.6 MUC1 SYP
11 bronchus adenoma 10.6 MUC1 SYP
12 epithelioid sarcoma 10.6 MUC1 SYP
13 hypogonadotropic hypogonadism without anosmia, x-linked 10.6 S100B SYP
14 proliferative type fibrocystic change of breast 10.6 MUC1 SYP
15 mannose-binding lectin protein deficiency 10.6 MUC1 VIM
16 vulvar angiokeratoma 10.6 MUC1 VIM
17 tabes dorsalis 10.6 MUC1 SYP
18 sm-ahnmd 10.6 S100B SYP
19 bladder colloid adenocarcinoma 10.6 MUC1 VIM
20 benallegue lacete syndrome 10.6 S100B VIM
21 cellular ependymoma 10.6 MUC1 VIM
22 strabismus 10.6 MUC1 S100B
23 phobic disorder 10.6 MUC1 S100B
24 lymphangiosarcoma 10.6 MUC1 VIM
25 persian gulf syndrome 10.5 MUC1 VIM
26 fallopian tube germ cell cancer 10.5 MUC1 VIM
27 ovary papillary carcinoma 10.5 MUC1 VIM
28 childhood pleomorphic rhabdomyosarcoma 10.5 MUC1 VIM
29 central nervous system melanocytic neoplasm 10.5 MUC1 SYP
30 pancreatic serous cystadenoma 10.5 MUC1 VIM
31 short-rib thoracic dysplasia 12 10.5 MUC1 VIM
32 migraine with aura 10.5 MUC1 SYP
33 ovarian mucinous adenocarcinoma 10.5 MUC1 VIM
34 small intestine neuroendocrine neoplasm 10.5 S100B VIM
35 extraskeletal mesenchymal chondrosarcoma 10.5 MUC1 VIM
36 skin papilloma 10.5 SYP VIM
37 secondary syphilis 10.5 MUC1 VIM
38 adult medulloblastoma 10.5 SYP VIM
39 mesenchymoma 10.5 MUC1 VIM
40 malignant breast melanoma 10.5 S100B VIM
41 juvenile xanthogranuloma 10.5 S100B VIM
42 spastic ataxia 3 10.5 MUC1 VIM
43 epicardium cancer 10.5 MUC1 S100B
44 classic variant of chromophobe renal cell carcinoma 10.5 MUC1 SYP
45 early-onset parkinson disease 10.5 S100B SYP
46 devriendt syndrome 10.5 GFAP SYP
47 hypogonadotropic hypogonadism-frontoparietal alopecia syndrome 10.5 GFAP SYP
48 dystonia 10.5 GFAP SYP
49 spinal cord ependymoma 10.5 GFAP SYP
50 neurofibroma of the esophagus 10.5 MDM2 MUC1

Graphical network of the top 20 diseases related to Anaplastic Ependymoma:



Diseases related to Anaplastic Ependymoma

Symptoms & Phenotypes for Anaplastic Ependymoma

UMLS symptoms related to Anaplastic Ependymoma:


headache, nausea, seizures, vomiting

MGI Mouse Phenotypes related to Anaplastic Ependymoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.17 GFAP MDM2 NF2 PTEN S100B SYP

Drugs & Therapeutics for Anaplastic Ependymoma

Drugs for Anaplastic Ependymoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 205)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
2
Donepezil Approved Phase 3,Phase 2 120014-06-4 3152
3
Dopamine Approved Phase 3 51-61-6, 62-31-7 681
4
Methylphenidate Approved, Investigational Phase 3 113-45-1 4158
5 Pancreatic Polypeptide Investigational Phase 3,Phase 1 59763-91-6
6 Central Nervous System Depressants Phase 3,Phase 1,Phase 2
7 Adjuvants, Anesthesia Phase 3
8 Analgesics Phase 3,Phase 2,Phase 1
9 Analgesics, Opioid Phase 3
10 Anesthetics Phase 3
11 Anesthetics, General Phase 3
12 Anesthetics, Intravenous Phase 3
13 Liver Extracts Phase 3,Phase 2,Phase 1
14 Narcotics Phase 3
15 Peripheral Nervous System Agents Phase 3,Phase 2,Phase 1
16 Cholinergic Agents Phase 3,Phase 2
17 Cholinesterase Inhibitors Phase 3,Phase 2
18 Neurotransmitter Agents Phase 3,Phase 2
19 Nootropic Agents Phase 3,Phase 2
20 Central Nervous System Stimulants Phase 3,Phase 2
21 Dopamine Agents Phase 3
22 Dexmethylphenidate Hydrochloride Phase 3
23 Dopamine Uptake Inhibitors Phase 3
24 Neurotransmitter Uptake Inhibitors Phase 3
25 Cola Nutraceutical Phase 3,Phase 1
26
Dacarbazine Approved, Investigational Phase 2,Phase 1 4342-03-4 5351166
27
Temozolomide Approved, Investigational Phase 2,Phase 1 85622-93-1 5394
28
Carmustine Approved Phase 1, Phase 2 154-93-8 2578
29
Ethanol Approved Phase 1, Phase 2 64-17-5 702
30
Cisplatin Approved Phase 2,Phase 1 15663-27-1 84093 441203 2767
31
Etoposide Approved Phase 2 33419-42-0 36462
32
Cyclophosphamide Approved, Investigational Phase 2 50-18-0, 6055-19-2 2907
33
Lenograstim Approved Phase 2,Phase 1 135968-09-1
34
Vincristine Approved, Investigational Phase 2 2068-78-2, 57-22-7 5978
35
Bevacizumab Approved, Investigational Phase 2 216974-75-3
36 Thiotepa Approved Phase 2,Phase 1 52-24-4 5453
37
Methotrexate Approved Phase 2 1959-05-2, 59-05-2 126941
38
Doxorubicin Approved, Investigational Phase 2 23214-92-8 31703
39
Tamoxifen Approved Phase 2 10540-29-1 2733526
40
Armodafinil Approved, Investigational Phase 2 112111-43-0
41
Modafinil Approved, Investigational Phase 2 68693-11-8 4236
42
Carboplatin Approved Phase 2,Phase 1 41575-94-4 10339178 498142 38904
43
Topotecan Approved, Investigational Phase 2 119413-54-6, 123948-87-8 60700
44 Piracetam Approved Phase 2 7491-74-9
45
Pregabalin Approved, Illicit, Investigational Phase 2 148553-50-8 5486971
46
Aldesleukin Approved Phase 2,Phase 1 85898-30-2, 110942-02-4
47
Paclitaxel Approved, Vet_approved Phase 2,Phase 1 33069-62-4 36314
48
Irinotecan Approved, Investigational Phase 2 97682-44-5, 100286-90-6 60838
49
Everolimus Approved Phase 2 159351-69-6 6442177
50
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189

Interventional clinical trials:

(show top 50) (show all 87)

id Name Status NCT ID Phase Drugs
1 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
2 Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors Completed NCT00369785 Phase 3 donepezil hydrochloride;Placebo
3 Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors Terminated NCT00031798 Phase 3 methylphenidate hydrochloride
4 Phase I/II Trial of Safety and Anti-tumor Efficacy of AXL1717(Picropodophyllin) in the Treatment of Recurrent Malignant Astrocytomas Unknown status NCT01721577 Phase 1, Phase 2 AXL1717
5 Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma Unknown status NCT00826241 Phase 2 Temozolomide;Lapatinib
6 Carmustine Followed By Surgery in Treating Patients With Recurrent Supratentorial Malignant Glioma or Metastatic Brain Neoplasm Unknown status NCT00009854 Phase 1, Phase 2 carmustine in ethanol
7 Etoposide Plus Cisplatin in Treating Patients With Recurrent Ependymomas Completed NCT00002876 Phase 2 cisplatin;etoposide
8 Combination Chemotherapy Plus Radiation Therapy in Treating Adult Patients With Brain Cancer Completed NCT00003309 Phase 2 cisplatin;cyclophosphamide;etoposide;vincristine sulfate
9 Poly-ICLC in Treating Patients With Recurrent or Progressive Anaplastic Glioma Completed NCT00058123 Phase 2 poly ICLC
10 Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors Completed NCT01836549 Phase 2 imetelstat sodium
11 Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer Completed NCT00492089 Phase 2 bevacizumab;placebo
12 Thiotepa Followed by Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Malignant Glioma Completed NCT00008008 Phase 2 cyclophosphamide;thiotepa
13 Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma Completed NCT00006258 Phase 2 cisplatin;cyclophosphamide;etoposide;methotrexate;vincristine sulfate
14 Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors Completed NCT00002608 Phase 2 cisplatin;doxorubicin hydrochloride;tamoxifen citrate
15 Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Cancers Completed NCT00002752 Phase 1, Phase 2
16 Armodafinil in Treating Fatigue Caused By Radiation Therapy in Patients With Primary Brain Tumors Completed NCT01032200 Phase 2 Armodafinil
17 Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging in Evaluating Patients Who Are Undergoing Treatment for Gliomas Completed NCT00274755 Phase 2 chemotherapy
18 Tamoxifen, Carboplatin, and Topotecan in Treating Patients With CNS Metastases or Recurrent Brain or Spinal Cord Tumors Completed NCT00541138 Phase 2 carboplatin;tamoxifen citrate;topotecan hydrochloride
19 Temozolomide in Treating Patients With Recurrent Glioblastoma Multiforme or Other Malignant Glioma Completed NCT00498927 Phase 2 temozolomide
20 Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor Completed NCT00070161 Phase 2 donepezil hydrochloride
21 Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and/or Radiation Therapy For Primary Brain Tumors Completed NCT00629889 Phase 2 levetiracetam;pregabalin
22 Chemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain Cancer Completed NCT00014573 Phase 2 carmustine;cisplatin;cyclophosphamide;paclitaxel
23 Veliparib and Temozolomide in Treating Patients With Recurrent Glioblastoma Completed NCT01026493 Phase 1, Phase 2 temozolomide 60 mg x 21 days;temozolomide 75 mg x 21 days;ABT-888 20 mg x 21 days;ABT-888 40 mg x 21 days;Temozolomide 150 mg x 5 days;ABT-888 40 mg x 5 days
24 Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary Brain Tumors Completed NCT00003478 Phase 1, Phase 2
25 Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) With Bevacizumab and Irinotecan for Malignant Glioma Completed NCT00352521 Phase 2 bevacizumab;irinotecan
26 Carboplatin and Bevacizumab for Recurrent Ependymoma Recruiting NCT01295944 Phase 2 Carboplatin;Bevacizumab
27 Everolimus for Children With Recurrent or Progressive Ependymoma Recruiting NCT02155920 Phase 2 Everolimus
28 Efficacy of Hypofractionated XRT w/Bev. + Temozolomide for Recurrent Gliomas Active, not recruiting NCT01478321 Phase 2 Temozolomide
29 Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma Active, not recruiting NCT00027846 Phase 2 carboplatin;cyclophosphamide;etoposide;vincristine sulfate;Mesna
30 Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer Active, not recruiting NCT00445965 Phase 2
31 Phase II Pediatric Study With Dabrafenib in Combination With Trametinib in Patients With HGG Not yet recruiting NCT02684058 Phase 2 dabrafenib;trametinib
32 Antineoplaston Therapy in Treating Patients With Ependymoma Terminated NCT00003479 Phase 2 Antineoplaston therapy (Atengenal + Astugenal)
33 Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Glioma Terminated NCT01095094 Phase 2 ritonavir;lopinavir
34 Photodynamic Therapy in the Treatment of Malignant Intracranial Tumors Withdrawn NCT00243490 Phase 2
35 Functional Magnetic Resonance Imaging and 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Treating Patients With Newly Diagnosed Brain Tumors Withdrawn NCT00005083 Phase 2
36 Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors Unknown status NCT00002647 Phase 1 verteporfin
37 Enzastaurin and Temozolomide in Treating Patients With Primary Gliomas Unknown status NCT00516607 Phase 1 enzastaurin hydrochloride;temozolomide
38 Lonafarnib and Temozolomide in Treating Patients With Recurrent Primary Supratentorial Gliomas Unknown status NCT00083096 Phase 1 lonafarnib;temozolomide
39 Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Gluco Completed NCT01082926 Phase 1
40 Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction Completed NCT00030498 Phase 1 erlotinib hydrochloride
41 Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors Completed NCT01131234 Phase 1 Gamma-Secretase Inhibitor RO4929097;Cediranib Maleate
42 RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma Completed NCT01119599 Phase 1 Gamma-Secretase Inhibitor RO4929097;Temozolomide
43 Mibefradil Dihydrochloride and Temozolomide in Treating Patients With Recurrent Glioma Completed NCT01480050 Phase 1 temozolomide;Mibefradil
44 Carmustine in Treating Patients With Recurrent Malignant Glioma Completed NCT00004028 Phase 1 carmustine
45 Cellular Adoptive Immunotherapy Using Genetically Modified T-Lymphocytes in Treating Patients With Recurrent or Refractory High-Grade Malignant Glioma Completed NCT00730613 Phase 1
46 Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to Treatment Completed NCT00544284 Phase 1 bortezomib;temozolomide
47 MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma Completed NCT00020579 Phase 1 entinostat
48 Monoclonal Antibody Therapy in Treating Patients With Leptomeningeal Cancer Completed NCT00003022 Phase 1
49 Monoclonal Antibody Therapy in Treating Patients With Recurrent Gliomas Completed NCT00002753 Phase 1
50 Sodium Stibogluconate and IFNa-2b Followed By CDDP, VLB and DTIC Treating Pts.With Advanced Melanoma or Other Cancers Completed NCT00498979 Phase 1 cisplatin;sodium stibogluconate;dacarbazine;vinblastine

Search NIH Clinical Center for Anaplastic Ependymoma

Genetic Tests for Anaplastic Ependymoma

Anatomical Context for Anaplastic Ependymoma

MalaCards organs/tissues related to Anaplastic Ependymoma:

39
Brain, Spinal Cord, Bone, Bone Marrow, Liver, T Cells, Kidney

Publications for Anaplastic Ependymoma

Articles related to Anaplastic Ependymoma:

(show top 50) (show all 91)
id Title Authors Year
1
Spinal cord anaplastic ependymoma induced by radiation treatment of breast cancer. ( 28555490 )
2017
2
Anaplastic Ependymoma With Ganglionic Differentiation: Report of a Rare Case and Implications in Diagnosis. ( 28554236 )
2017
3
Rapid autopsy of a patient with recurrent anaplastic ependymoma. ( 28942746 )
2017
4
Hormonal based treatment of ovarian anaplastic ependymoma with anastrozole. ( 28393092 )
2017
5
Encouraging option of multi-staged gross total resection for a C11orf-RelA fusion-positive supratentorial anaplastic ependymoma. ( 28831588 )
2017
6
"Drop" Metastases from an Operated Case of Intracranial Anaplastic Ependymoma Identified on Fluoro-2-deoxyglucose Positron Emission Tomography/Computed Tomography. ( 28242994 )
2017
7
Angiocentric glioma transformed into anaplastic ependymoma: Review of the evidence for malignant potential. ( 27742374 )
2016
8
Pure extra-axial supratentorial anaplastic ependymoma with no cortical attachment: A rare case. ( 26954823 )
2016
9
Radiation-induced anaplastic ependymoma mimicking a skull base meningioma: A case report. ( 26893630 )
2016
10
Re-irradiation of recurrent anaplastic ependymoma using radiosurgery or fractionated stereotactic radiotherapy. ( 26682738 )
2016
11
Supratentorial extraventricular WHO grade III (anaplastic) ependymoma 17 years after total removal of WHO grade II ependymoma of the fourth ventricle. ( 27215793 )
2016
12
Magnetic resonance imaging findings of extraventricular anaplastic ependymoma: A report of 11 cases. ( 27602137 )
2016
13
Brain Tumor in an In Vitro Fertilization-Facilitated Pregnancy: Fourth Ventricle Anaplastic Ependymoma in the Second Trimester. ( 27330925 )
2016
14
Paediatric Intracranial Anaplastic Ependymoma: The Role of Multiple Surgical Resections for Disease Relapse in Maintaining Quality of Life and Prolonged Survival. ( 25871983 )
2015
15
Supratentorial extraventricular anaplastic ependymoma with extracranial metastasis. ( 25455735 )
2015
16
Anaplastic ependymoma of spinal cord presented with lower back pain. ( 25843250 )
2015
17
An extraneural primary anaplastic ependymoma at the subcutaneous inguinal region: Report of a rare case. ( 26549094 )
2015
18
An 11 Year Old Child with a Right Parieto-Occipital Lesion. Anaplastic Ependymoma (WHO Grade III) with Granular Cell Features. ( 26086056 )
2015
19
Temozolomide Treatment for Pediatric Refractory Anaplastic Ependymoma With Low MGMT Protein Expression. ( 26305586 )
2015
20
Anaplastic Ependymoma in a Child With Sickle Cell Anemia: A Case Report Highlighting Treatment Challenges for Young Children With Central Nervous System Tumors and Underlying Vasculopathy. ( 26488903 )
2015
21
Role of Evaluating MGMT Status and 1p36 Deletion in Radiosurgery-Induced Anaplastic Ependymoma That Rapidly and Completely Resolved by Temozolomide Alone: Case Report and Review of the Literature. ( 26251808 )
2015
22
Supratentorial extraventricular anaplastic ependymoma in a child. ( 24623545 )
2014
23
Ectopic cortical anaplastic ependymoma: an unusual case report and literature review. ( 25051164 )
2014
24
Anaplastic ependymoma of the third ventricle. ( 24643478 )
2014
25
Treatment of Ovarian Anaplastic Ependymoma by an Aromatase Inhibitor. ( 24413241 )
2014
26
Supratentorial Extraventricular Anaplastic Ependymoma Presenting with Repeated Intratumoral Hemorrhage. ( 25408930 )
2014
27
A headache presenting in the emergency room, a clinical manifestation of an unfortunate diagnosis (grade III left frontal anaplastic ependymoma with 1p deletion). ( 23912654 )
2013
28
Supratentorial gross-totally resected non-anaplastic ependymoma: population based patterns of care and outcomes analysis. ( 24085643 )
2013
29
Cisplatin and temozolomide combination in the treatment of supratentorial anaplastic ependymoma. ( 24192541 )
2013
30
Cortical anaplastic ependymoma with significant desmoplasia: a case report and literature review. ( 24455359 )
2013
31
Extra and intramedullary anaplastic ependymoma in thoracic spinal cord. ( 24757483 )
2013
32
Supratentorial extraventricular anaplastic ependymoma in an adult with repeated intratumoral hemorrhage. ( 23546851 )
2013
33
Anaplastic ependymoma with ependymoblastic multilayered rosettes. ( 23791209 )
2013
34
Radiation-induced anaplastic ependymoma with a remarkable clinical response to temozolomide: a case report. ( 23163298 )
2013
35
Anaplastic ependymoma with holocordal and intracranial meningeal carcinomatosis and holospinal bone metastases. ( 23422903 )
2013
36
Metronomic cyclophosphamide with cisplatin and bevacizumab: a new chemotherapeutic regimen for refractory anaplastic ependymoma. ( 23155280 )
2012
37
Purely cortical anaplastic ependymoma. ( 23119204 )
2012
38
Sacrococcygeal myxopapillary ependymoma with anaplastic ependymoma component in an infant. ( 23560014 )
2012
39
Supratentorial extra-axial anaplastic ependymoma mimicking a meningioma. ( 22406799 )
2012
40
Tandem high-dose chemotherapy and autologous stem cell transplantation for anaplastic ependymoma in children younger than 3 years of age. ( 22081297 )
2012
41
Cystic with mural nodule: Unusual radiological presentation of supratentorial anaplastic ependymoma. ( 23248684 )
2012
42
Anaplastic ependymoma simulating glioblastoma in the cerebrum of an adult. ( 21833575 )
2012
43
An anaplastic ependymoma presenting as an intrinsic brainstem glioma. ( 22406810 )
2012
44
Spinal intradural, extramedullary anaplastic ependymoma with an extradural component: Case report and review of the literature. ( 21918734 )
2011
45
Extraventricular anaplastic ependymoma with metastasis to scalp and neck. ( 21222217 )
2011
46
Isolated extracranial recurrence of anaplastic ependymoma. ( 20830772 )
2011
47
Metachronous occurrence of a temporal ganglioglioma and a bifrontal anaplastic ependymoma: coincidence or an explainable pathological curiosity? ( 21501061 )
2011
48
Recurrent posterior fossa anaplastic ependymoma with prominent chondroid metaplasia: a case report and review of literature. ( 21045418 )
2010
49
Anaplastic ependymoma with sclerotic bone metastases. ( 20979177 )
2010
50
Supratentorial extraventricular anaplastic ependymoma in a 10-year-old girl. ( 21555909 )
2010

Variations for Anaplastic Ependymoma

Expression for Anaplastic Ependymoma

Search GEO for disease gene expression data for Anaplastic Ependymoma.

Pathways for Anaplastic Ependymoma

Pathways related to Anaplastic Ependymoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 12.06 MUC1 NF2 VIM
2 12.02 MDM2 PTEN VIM
3 11.77 GFAP NF2 S100B SYP
4 11.48 MDM2 NF2 PTEN
5
Show member pathways
11.37 GFAP MDM2 S100B
6 10.98 MDM2 PTEN
7 10.83 GFAP S100B SYP VIM

GO Terms for Anaplastic Ependymoma

Cellular components related to Anaplastic Ependymoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell projection GO:0042995 9.13 NF2 PTEN VIM
2 neuron projection GO:0043005 8.92 NF2 PTEN SYP VIM

Biological processes related to Anaplastic Ependymoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cellular response to hypoxia GO:0071456 9.5 MDM2 PTEN S100B
2 cellular response to organic substance GO:0071310 9.46 MDM2 SYP
3 regulation of neuronal synaptic plasticity GO:0048168 9.43 S100B SYP
4 negative regulation of neuron projection development GO:0010977 9.16 MDM2 VIM
5 intermediate filament organization GO:0045109 9.1 VIM
6 astrocyte development GO:0014002 9.07 VIM
7 Bergmann glial cell differentiation GO:0060020 8.96 VIM
8 intermediate filament-based process GO:0045103 8.65 VIM
9 long-term synaptic potentiation GO:0060291 8.62 PTEN S100B

Molecular functions related to Anaplastic Ependymoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.1 GFAP MDM2 PTEN S100B SYP VIM

Sources for Anaplastic Ependymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....