Anaplastic Meningioma malady

MalaCards: Anaplastic Meningioma, also known as malignant meningioma, is related to meningioma and meninges hemangiopericytoma. An important gene associated with Anaplastic Meningioma is CDKN2B (cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)), and among its related pathways are Pancreatic cancer and Signal transduction_PTEN pathway. The compounds egcg and threonine have been mentioned in the context of this disorder. Affiliated tissues include b cells, and related mouse phenotypes are endocrine/exocrine gland and respiratory system.

anaplastic meningioma 8 32 malignant meningioma 43

Diseases related to anaplastic meningioma by text searches and GeneDecks gene sharing:

(show top 50)    (show all 582)

id	Related Disease	Score	Top Affiliating Genes
1	meningioma	34.4	PCNA, MKI67, PGR
2	meninges hemangiopericytoma	28.4	RB1, VIM, MUC1, CDH1, NF2, EPB41L3
3	hemangiopericytoma	26.3	RB1, VIM, VEGFA, KDR, MUC1, S100A1
4	hepatoblastoma	24.3	PCNA, RB1, VIM, CDKN2C, CDKN2B, CDKN1B
5	meningitis	23.2	PCNA, RB1, VIM, VEGFA, MUC1, CDH1
6	laryngitis	20.4	PCNA, RB1, VIM, VEGFA, KDR, MUC1
7	esophagitis	19.9	PCNA, RB1, VIM, VEGFA, KDR, MUC1
8	carcinoma	18.9	PCNA, RB1, VIM, VEGFA, KDR, MUC1
9	prostatitis	18.0	PCNA, RB1, VIM, VEGFA, KDR, LEPREL4
10	mature t-cell and nk-cell neoplasm	13.7	CDKN1B, PTEN
11	bannayan-riley-ruvalcaba syndrome	13.7	CDKN3, PTEN
12	unilateral retinoblastoma	13.6	RB1, MKI67
13	brain ependymoma	13.6	NF2, GFAP
14	klatskin's tumor	13.5	VIM, MMP2, MMP9
15	hepatic angiomyolipoma	13.5	RB1, VIM, CDKN2A
16	odontogenic myxoma	13.5	VIM, MMP2, MMP9
17	verruciform xanthoma of skin	13.5	VIM, CD68
18	refractive error	13.5	MMP2, MMP9, NF2
19	rhabdoid meningioma	13.4	VIM, GFAP
20	blastic plasmacytoid dendritic cell	13.4	CDKN1B, CDKN2A
21	spinal cancer	13.4	NF2, GFAP
22	cancer progression/metastasis	13.4	MMP2, MMP9, EPB41L3
23	familial melanoma	13.4	CDKN2C, CDKN2A, CDK4
24	neurofibromatosis	13.4	CD44, NF2, EPB41L3
25	endometrial carcinoma, somatic	13.4	CDH1, PTEN
26	astroblastoma	13.4	VIM, GFAP
27	neurilemmoma	13.4	VIM, NF2, GFAP
28	dermatofibrosarcoma protuberans	13.4	VIM, PDGFB
29	liver sarcoma	13.4	VIM, CD68
30	acute lymphoblastic leukemia, childhood	13.3	CDKN2B, CDKN1B, CDKN2A, CDK4
31	clear cell ependymoma	13.3	VIM, MUC1
32	prostate stromal sarcoma	13.3	VIM, MUC1
33	spindle cell lipoma	13.3	VIM, S100A1, CDK4
34	tongue cancer	13.3	CDH1, MMP2, MMP9
35	langerhans-cell histiocytosis	13.3	S100A1, PDGFB
36	clear cell meningioma	13.3	VIM, MUC1, MKI67
37	inverted papilloma	13.3	PCNA, CDKN1B, MKI67
38	endometrial mucinous adenocarcinoma	13.3	VIM, MUC1, CDKN2A
39	microcystic meningioma	13.3	VEGFA, MMP2, MMP9
40	adenoid squamous cell carcinoma	13.3	VIM, MUC1
41	peripheral primitive neuroectodermal tumor	13.3	RB1, VIM, S100A1, ETS1
42	mixed glioma	13.2	VIM, GFAP
43	reticulosarcoma	13.2	MUC1, CDKN1B, CD68, CTSD
44	cellular schwannoma	13.2	VIM, S100A1, NF2, GFAP
45	adenomatoid tumor	13.2	VIM, MUC1, MMP2
46	inflammatory myofibroblastic tumor	13.2	VIM, S100A1, CDK4, MKI67
47	chondroid chordoma	13.2	VIM, MUC1, S100A1
48	perineurioma	13.2	VIM, MUC1, NF2
49	oligodendroglioma	13.2	CDKN2C, CDKN2B, CDKN2A, PTEN, GFAP
50	ameloblastic carcinoma	13.2	MUC1, MKI67

Approved drugs:

Drug clinical trials:

MalaCards organs/tissues related to anaplastic meningioma:

²²

MGI Mouse Phenotypes related to anaplastic meningioma:

²⁵ (show all 25)

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	endocrine/exocrine gland phenotype	MP:0005379	10.0	CDKN2C, CDKN1B, NF2, CDKN2B, EPB41L3
2	respiratory system phenotype	MP:0005388	9.9	INSR, PDGFB, NF2, ALPL
3	liver/biliary system phenotype	MP:0005370	9.2	TP53, NF2, VEGFA
4	limbs/digits/tail phenotype	MP:0005371	9.0	RB1, ALPL, MMP9, CD44, VEGFA
5	renal/urinary system phenotype	MP:0005367	8.9	INSR, CDKN2C, PDGFB, NF2, PTEN, CDK4
6	pigmentation phenotype	MP:0001186	8.8	RB1, CDKN1B, CDKN2A, TP53, PTEN, PDGFB
7	hematopoietic system phenotype	MP:0005397	8.8	PDGFB, AKT3, ETS1, ALPL, CD68, CDK4
8	embryogenesis phenotype	MP:0005380	8.8	PGR, CDK4, VIM, NF2, ETS1, ALPL
9	nervous system phenotype	MP:0003631	8.5	CDK4, CD44, MMP2, INSR, AKT3, PTEN
10	normal phenotype	MP:0002873	7.7	AKT3, GFAP, INA, CD44, EPB41L3, PGR
11	reproductive system phenotype	MP:0005389	7.7	MMP9, CDH1, CD44, CDKN1B, CDKN2B, CDKN2C
12	immune system phenotype	MP:0005387	7.6	CD68, CDK4, CDKN1B, CDKN2B, CDKN2C, KDR
13	integument phenotype	MP:0010771	7.4	RB1, TP53, MAP2K1, CD44, CDK4, CDKN1B
14	no phenotypic analysis	MP:0003012	7.0	TP53, CDKN1B, PDGFB, CDH1, PCNA, CD44
15	behavior/neurological phenotype	MP:0005386	6.9	VIM, KDR, S100A1, CDKN2C, CDKN1B, CD44
16	skeleton phenotype	MP:0005390	6.7	CD68, MMP2, ALPL, TP53, PTEN, NF2
17	growth/size phenotype	MP:0005378	6.7	NF2, CD44, GFAP, PDGFB, CDKN2C, MAP2K1
18	mortality/aging	MP:0010768	6.6	KDR, CDKN2C, CDKN1B, CDK4, CDH1, ALPL
19	tumorigenesis	MP:0002006	6.1	CD44, CDK4, CDKN1B, CDKN2B, CDKN2C, MUC1
20	digestive/alimentary phenotype	MP:0005381	6.0	MAP2K1, MUC1, CDKN1B, CDKN2A, CDK4, PTEN
21	vision/eye phenotype	MP:0005391	6.0	CDKN2A, CDKN1B, MUC1, KDR, VEGFA, VIM
22	muscle phenotype	MP:0005369	5.6	KDR, PTEN, PDGFB, GFAP, PGR, CDK4
23	cardiovascular system phenotype	MP:0005385	4.7	PGR, GFAP, PDGFB, PTEN, TP53, ETS1
24	cellular phenotype	MP:0005384	3.9	MMP9, CDH1, INSR, CD44, CDK4, MAP2K1
25	homeostasis/metabolism phenotype	MP:0005376	3.6	RB1, VIM, VEGFA, KDR, ALPL, ETS1

Articles related to anaplastic meningioma:

(show all 18)

id	Title	Authors	Year	Affiliating Genes
1	Increased STAT-3 and synchronous activation of Raf-1-MEK-1-MAPK, and phosphatidylinositol 3-Kinase-Akt-mTOR pathways in atypical and anaplastic meningiomas. (19034385)	Johnson M.D.... Bakos R.S.	2009	MAP2K1
2	Expression of cell adhesion proteins and proteins related to angiogenesis and fatty acid metabolism in benign, atypical, and anaplastic meningiomas. (18418552)	Panagopoulos A.T.... Colquhoun A.	2008	KDR, CDH1, MMP2
3	De novo versus transformed atypical and anaplastic meningiomas: comparisons of clinical course, cytogenetics, cytokinetics, and outcome. (17881961)	KrayenbA1hl N.... Al-Mefty O.	2007	PGR
4	Ets-1 is up-regulated together with its target gene products matrix metalloproteinase-2 and matrix metalloproteinase-9 in atypical and anaplastic meningiomas. (16722933)	Okuducu A.F.... von Deimling A.	2006	MMP2, MMP9, ETS1
5	Expression of extracellular matrix-degrading proteins in classic, atypical, and anaplastic meningiomas. (16563650)	von Randow A.J.... Tews D.S.	2006	CTSD, MMP9
6	Microarray-based gene expression profiling of benign, atypical and anaplastic meningiomas identifies novel genes associated with meningioma progression. (15540215)	Wrobel G.... Lichter P.	2005	AKT3
7	Aberrant CpG island hypermethylation profile is associated with atypical and anaplastic meningiomas. (15892004)	Liu Y.... Ng H.K.	2005	CDKN2B
8	Anaplastic meningioma versus meningeal hemangiopericytoma: immunohistochemical and genetic markers. (15668900)	Rajaram V.... Perry A.	2004	NF2, EPB41L3
9	Immunohistochemical study of anaplastic meningioma with special reference to the phenotypic change of intermediate filament protein. (12913843)	Ikeda H.... Yoshimoto T.	2003	VIM, MUC1, INA
10	A role for chromosome 9p21 deletions in the malignant progression of meningiomas and the prognosis of anaplastic meningiomas. (11958372)	Perry A.... Scheithauer B.W.	2002	CDKN2A
11	Immunohistochemical study of Ki-67 (MIB-1), p53 protein, p21WAF1, and p27KIP1 expression in benign, atypical, and anaplastic meningiomas. (11567227)	Amatya V.J.... Inai K.	2001	CDKN1B, MKI67
12	Alterations of the tumor suppressor genes CDKN2A (p16(INK4a)), p14(ARF), CDKN2B (p15(INK4b)), and CDKN2C (p18(INK4c)) in atypical and anaplastic meningiomas. (11485924)	Bostrom J.... Reifenberger G.	2001	CDKN2A, CDKN2B, CDKN2C
13	PS6K amplification characterizes a small subset of anaplastic meningiomas. (11211609)	Cai D.X.... Perry A.	2001	INSR
14	Involvement of disregulated c-myc but not c-sis/PDGF in atypical and anaplastic meningiomas. (11311470)	Nagashima G.... Hirakawa K.	2001	PDGFB
15	Xanthomatous changes in atypical and anaplastic meningiomas. Light and electron microscopic investigations. (11043974)	Taraszewska A.... Bogucki J.	2000	CD68
16	Analysis of genomic alterations in benign, atypical, and anaplastic meningiomas: toward a genetic model of meningioma progression. (9405679)	Weber R.G.... Lichter P.	1997	CDK4, TP53
17	Cytology and immunohistochemistry of anaplastic meningiomas in squash preparations. A report of two cases. (7531379)	Kobayashi S.... Ohmori M.	1995	VIM, S100A1
18	Atypical (anaplastic) meningioma: relationship between histologic features and recurrence--a clinicopathologic study. (2187642)	Chen W.Y.... Liu H.C.	1990	VIM, S100A1

Genes related to anaplastic meningioma according to GeneCards:

(show all 37)

id	Symbol	Description	Score	GeneCards Section Context
1	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	11.0	Publications
2	ALPL	alkaline phosphatase, liver/bone/kidney	11.0
3	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	11.0	Publications
4	CTSD	cathepsin D	11.0	Publications
5	NF2	neurofibromin 2 (merlin)	11.0	Publications
6	MKI67	antigen identified by monoclonal antibody Ki-67	11.0	Publications
7	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	11.0	Publications
8	CDKN3	cyclin-dependent kinase inhibitor 3	11.0
9	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	11.0	Publications
10	CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	11.0	Publications
11	RB1	retinoblastoma 1	11.0
12	PTEN	phosphatase and tensin homolog	11.0
13	CDKN2A	cyclin-dependent kinase inhibitor 2A	11.0	Publications
14	LEPREL4	leprecan-like 4	11.0
15	RRP36	ribosomal RNA processing 36 homolog (S. cerevisiae)	11.0
16	FABP7	fatty acid binding protein 7, brain	11.0	Publications
17	CD68	CD68 molecule	11.0	Publications
18	INA	internexin neuronal intermediate filament protein, alpha	11.0	Publications
19	CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	11.0	Publications
20	S100A1	S100 calcium binding protein A1	11.0	Publications
21	TXNDC16	thioredoxin domain containing 16	11.0	Disorders
22	PDGFB	platelet-derived growth factor beta polypeptide	11.0	Publications
23	VIM	vimentin	11.0	Publications
24	EPB41L3	erythrocyte membrane protein band 4.1-like 3	11.0	Publications
25	CD44	CD44 molecule (Indian blood group)	11.0	Publications
26	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	11.0	Publications
27	CDK4	cyclin-dependent kinase 4	11.0	Publications
28	MAP2K1	mitogen-activated protein kinase kinase 1	11.0	Publications
29	INSR	insulin receptor	11.0	Publications
30	KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	11.0	Publications
31	GFAP	glial fibrillary acidic protein	11.0
32	MUC1	mucin 1, cell surface associated	11.0	Publications
33	PCNA	proliferating cell nuclear antigen	11.0	Publications
34	CDH1	cadherin 1, type 1, E-cadherin (epithelial)	11.0	Publications
35	PGR	progesterone receptor	11.0	Publications
36	TP53	tumor protein p53	11.0	Publications
37	VEGFA	vascular endothelial growth factor A	11.0	Publications

Pathways related to anaplastic meningioma according to GeneDecks:

(show top 50)    (show all 62)

id	Pathway	Score	Top Affiliating Genes
1	Pancreatic cancer20	10.6	AKT3
2	Signal transduction_PTEN pathway41	10.4	PCNA
3	Renal cell carcinoma20	10.2	PDGFB, AKT3, ETS1
4	Cell cycle Regulation of G1/S transition (part 1)10	10.1	CDK4, CDKN2A, CDKN2B, CDKN1B
5	Cell cycle_Regulation of G1/S transition (part 1)41	10.0	CDKN1B, CDKN2A, CDK4, CDKN2B
6	Adipocytokines & Insulin Signaling37	10.0	INSR, AKT3
7	Transcription Receptor-mediated HIF regulation10	10.0	INSR, MAP2K1, AKT3
8	Akt Signaling36	10.0	PDGFB
9	Cytoskeleton remodeling FAK signaling10	9.9	AKT3, MAP2K1, KDR
10	Development VEGF-family signaling10	9.9	AKT3, KDR, MAP2K1
11	Angiogenesis3	9.9	MMP2, KDR, ETS1, MMP9
12	HGF Pathway36	9.9	RB1, CDKN1B, MAP2K1, ETS1, AKT3
13	Development VEGF signaling and activation10	9.9	AKT3, KDR, MAP2K1
14	Non-small cell lung cancer20	9.7	AKT3, MAP2K1, CDKN2A, RB1, CDK4
15	Signal transduction PTEN pathway10	9.7	PCNA, MAP2K1, AKT3, PTEN
16	Development_EGFR signaling pathway41	9.6	AKT3, MMP9, MAP2K1, MMP2
17	p53 Signaling36	9.6	PTEN, CDK4, TP53
18	Inhibition of Ribosome Biogenesis by p14(ARF)36	9.6	RB1, CDKN2A, TP53
19	Cell Cycle, Mitotic38	9.5	CDKN2C, CDKN2A, RB1, PCNA, CDKN1B
20	Transcription P53 signaling pathway10	9.4	VEGFA, TP53, CDKN2A
21	Development_VEGF-family signaling41	9.4	KDR, VEGFA, MAP2K1, AKT3
22	Development VEGF signaling via VEGFR2 - generic cascades10	9.4	AKT3, VEGFA, MAP2K1, KDR
23	Development_VEGF signaling and activation41	9.3	AKT3, VEGFA, KDR, MAP2K1
24	VEGF Signaling Pathway34	9.3	MAP2K1, KDR, AKT3, VEGFA
25	Transcription_Receptor-mediated HIF regulation41	9.3	PTEN, AKT3, MAP2K1, VEGFA, INSR
26	p53 signaling pathway20	9.3	PTEN, CDK4, CDKN2A, TP53
27	Cytoskeleton remodeling_FAK signaling41	9.3	MAP2K1, AKT3, PTEN, KDR, VEGFA
28	Endometrial cancer20	9.1	CDH1, MAP2K1, TP53, PTEN
29	G1-S Phase Transition36	9.1	CDKN1B, RB1, CDKN2C, TP53, CDK4, CDKN2A
30	Cyclins and Cell Cycle Regulation36	9.1	CDKN2A, TP53, CDK4, CDKN1B, CDKN2B, CDKN2C
31	VEGF signaling pathway20	9.0	KDR, VEGFA, MAP2K1, AKT3
32	Signal transduction_AKT signaling41	9.0	TP53, AKT3, CDKN1B, PCNA, PTEN
33	Focal adhesion20	9.0	KDR, MAP2K1, PDGFB, VEGFA, AKT3, PTEN
34	Small cell lung cancer20	9.0	CDKN2B, CDKN1B, AKT3, CDK4, TP53, PTEN
35	ILK Signaling36	8.9	KDR, VIM, AKT3, INSR, CDH1, PDGFB
36	EGF Pathway36	8.9	MUC1, CDH1, MAP2K1, AKT3
37	p53 Mediated Apoptosis36	8.8	AKT3, PDGFB, TP53, PTEN, KDR
38	Prostate cancer20	8.8	TP53, CDKN1B, MAP2K1, AKT3, PDGFB, RB1
39	Colorectal Cancer Metastasis36	8.8	MMP2, CDH1, MAP2K1, TP53, MMP9
40	Chronic myeloid leukemia20	8.8	TP53, RB1, CDKN1B, CDKN2A, CDK4, MAP2K1
41	Transcription_P53 signaling pathway41	8.8	VEGFA, TP53, MMP2, CDKN2A, KDR, RB1
42	Cell cycle20	8.6	TP53, CDKN2A, PCNA, CDKN2C, CDKN2B, CDKN1B
43	Cell Cycle / Checkpoint Control3	8.6	TP53, CDKN2B, CDK4, CDKN2C, CDKN1B, CDKN2A
44	Glioma20	8.6	RB1, PDGFB, TP53, AKT3, MAP2K1, CDK4
45	Glioblastoma Multiforme36	8.5	RB1, TP53, PDGFB, NF2, PTEN, AKT3
46	Melanoma20	8.1	CDK4, CDH1, MAP2K1, AKT3, TP53, PTEN
47	Bladder cancer20	7.9	TP53, MAP2K1, MMP9, MMP2, CDH1, CDK4
48	Pathways in cancer20	7.6	VEGFA, MMP9, RB1, PTEN, TP53, AKT3
49	Pancreatic Adenocarcinoma36	7.4	CDKN2B, CDKN2C, KDR, RB1, CDKN1B, CDKN2A
50	Molecular Mechanisms of Cancer36	7.2	CDKN1B, MAP2K1, TP53, PTEN, PDGFB, CDKN2C

Compounds related to anaplastic meningioma according to GeneDecks:

(show top 50)    (show all 205)

id	Compound	Score	Top Affiliating Genes
1	egcg32	10.6	MAP2K1
2	threonine32	10.1	CDKN2C, CDKN2B, CDKN1B, NF2
3	h2o232	9.8	MAP2K1, INSR, CDKN3
4	arginine32	9.1	GFAP, ETS1, MAP2K1, CD44, CDK4
5	rapamycin32 42	10.0	RB1, VIM, KDR, VEGFA, CDK4, NF2
6	12-o-tetradecanoylphorbol 13-acetate32	8.7	CTSD, CDKN1B, CD44, CDH1, RB1, MMP2
7	tgf beta132	8.7	MAP2K1, MKI67, MMP2, CDH1, CDK4, CDKN1B
8	ly29400232	8.5	AKT3, MAP2K1, MMP9, MMP2, VEGFA, CDKN1B
9	biotin32 9 18 9	11.4	MUC1, INSR, MKI67, RB1, VIM, CDKN3
10	progestin32	8.3	INSR, CDH1, CDK4, KDR, VEGFA, VIM
11	hematoxylin32	8.1	GFAP, PTEN, MKI67, MMP9, CDH1, CDKN2A
12	trastuzumab32 34 9 9	11.1	MUC1, CDKN3, PGR, CTSD, PTEN, CDKN1B
13	celecoxib32 42 34 9 18 9	13.1	MAP2K1, MKI67, CDH1, CDKN1B, KDR, VEGFA
14	gefitinib32 34 9 9	11.0	VIM, VEGFA, KDR, CDKN1B, CDKN3, CDK4
15	etoposide32 42 9 9	10.9	PCNA, CDKN3, RB1, CDKN1B, CD44, CDH1
16	pd 98,05932	7.9	MMP2, CDK4, CDKN1B, CDKN2B, RB1, CDH1
17	formaldehyde32 18	8.8	RB1, PCNA, MUC1, CDKN1B, GFAP, CTSD
18	phosphatidylinositol32	7.8	RB1, KDR, CDKN1B, CDKN3, CD44, MMP2
19	methotrexate32 34 42 9 9	11.7	MMP2, CDKN2A, MMP9, MKI67, PCNA, PGR
20	cytarabine32 34 9 9	10.6	GFAP, TP53, CDKN2A, CDKN1B, CDKN2B, MUC1
21	agar32	7.6	MUC1, CDKN1B, CDKN2A, CDK4, CDH1, MAP2K1
22	n acetylcysteine32	7.5	MMP9, TP53, PCNA, CDKN1B, CDKN2A, CDK4
23	glycogen32 18	8.4	GFAP, PTEN, CDK4, MAP2K1, MUC1, VIM
24	matrigel32	7.3	MAP2K1, ETS1, GFAP, CDH1, MMP9, MMP2
25	retinoic acid32 42 18	9.3	CDKN2A, CDKN3, CDK4, CD44, MMP9, INA
26	progesterone32 42 9 18 9	11.3	GFAP, PGR, EPB41L3, S100A1, CDKN1B, CDKN2A
27	estradiol32 9 18 9	10.3	MKI67, PGR, PCNA, RB1, VIM, MAP2K1
28	estrogen32	7.2	PCNA, KDR, S100A1, CDH1, MMP2, MKI67
29	butyrate32	7.2	RB1, VIM, MUC1, CDKN1B, CDKN2A, CDKN3
30	thymidylate32	7.2	MKI67, CDH1, CDK4, CDKN2A, VEGFA, VIM
31	resveratrol32 9 18 9	10.2	TP53, CDK4, PCNA, RB1, VEGFA, CDKN1B
32	arsenite32 18	8.1	CDKN3, MMP9, MAP2K1, TP53, PTEN, PGR
33	actinomycin d32	7.1	INSR, CDKN3, MUC1, CD44, VEGFA, RB1
34	sb 20358032 42	8.1	INSR, RB1, TP53, ETS1, MMP2, CDH1
35	doxorubicin32 34 9 9	10.0	PGR, PTEN, CTSD, VIM, KDR, CDKN1B
36	cysteine32	6.7	KDR, GFAP, NF2, CTSD, MUC1, S100A1
37	alanine32	6.4	CTSD, GFAP, PGR, CDKN2A, PTEN, CDK4
38	thymidine32 18	7.2	TP53, CTSD, PDGFB, GFAP, EPB41L3, ETS1
39	tamoxifen32 34 9 9	9.1	CDH1, CDKN1B, MUC1, KDR, VEGFA, VIM
40	5fluorouracil32	6.0	MUC1, PCNA, RB1, PGR, CTSD, PTEN
41	testosterone32 9 18 9	8.9	PCNA, RB1, VIM, MUC1, CDKN1B, CDKN2A
42	cycloheximide32	5.9	VIM, VEGFA, GFAP, PGR, PDGFB, CTSD
43	genistein32 9 18 9	8.8	CDKN1B, CDKN2A, CDKN3, GFAP, CDK4, CDH1
44	vegf32	5.8	PCNA, KDR, MUC1, CDKN1B, CDKN3, CDH1
45	tyrosine32	5.7	CDH1, PTEN, CD44, CDK4, CDKN3, CDKN1B
46	cisplatin32 34 9 9	8.6	PCNA, RB1, VEGFA, KDR, MUC1, CDKN1B
47	dexamethasone32 42 34 9 9	9.5	VIM, VEGFA, KDR, MUC1, CDKN1B, CDKN2A
48	paclitaxel32 34 9 9	8.4	CDKN2A, CDK4, CD44, PGR, GFAP, CTSD
49	serine32	4.7	PDGFB, CD44, CDK4, CDKN3, CDKN2A, CDKN1B
50	paraffin32	4.3	CD44, CD68, CDH1, MMP2, MMP9, MKI67

Cellular components related to anaplastic meningioma according to GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	nucleus	GO:005634	5.3	PGR, CDK4, CDKN2A, CDKN1B, CDKN2B, CDKN2C
2	cytoplasm	GO:005737	4.2	EPB41L3, CDH1, CDKN2A, CDKN1B, CDKN2B, CDKN2C

Biological processes related to anaplastic meningioma according to GeneDecks:

(show all 20)

id	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of phosphorylation	GO:042326	10.2	CDKN2A, CDKN1B, CDKN2B, CDKN2C
2	regulation of cyclin-dependent protein kinase activity	GO:000079	10.0	CDKN2B, PTEN, CDKN3, CDKN1B, CDKN2C
3	Bergmann glial cell differentiation	GO:060020	9.9	VIM, GFAP
4	G1 phase of mitotic cell cycle	GO:000080	9.8	CDKN1B, RB1, CDKN2C, CDKN2B, CDKN2A, CDK4
5	response to estradiol stimulus	GO:032355	9.8	PDGFB, ETS1, MMP9, INSR
6	transformation of host cell by virus	GO:019087	9.7	MMP9, INSR
7	induction of apoptosis	GO:006917	9.7	CDKN2C, PTEN, ETS1, CDKN2A, CDKN1B
8	activation of protein kinase activity	GO:032147	9.6	PDGFB, INSR, VEGFA
9	positive regulation of angiogenesis	GO:045766	9.5	KDR, MMP9, ETS1, VEGFA
10	response to antibiotic	GO:046677	9.3	ALPL, ETS1, TP53
11	G1/S transition of mitotic cell cycle	GO:000082	9.3	PCNA, CDKN3, CDKN2A, CDKN2C, CDKN1B, RB1
12	negative regulation of cell growth	GO:030308	9.3	TP53, CDKN2A, CDKN2C, RB1, CDKN1B
13	mitotic cell cycle	GO:000278	9.3	PCNA, RB1, CDKN2C, CDKN2B, CDKN1B, CDKN2A
14	Ras protein signal transduction	GO:007265	9.2	CDKN2A, RB1, MAP2K1, TP53
15	positive regulation of cell migration	GO:030335	9.0	ETS1, KDR, INSR, VEGFA, MAP2K1, PDGFB
16	positive regulation of peptidyl-tyrosine phosphorylation	GO:050731	8.9	VEGFA, PDGFB, TP53, CD44
17	cell cycle arrest	GO:007050	8.8	CDKN2A, RB1, CDKN2B, CDKN1B, MAP2K1, CDKN2C
18	positive regulation of cell proliferation	GO:008284	8.6	PDGFB, PTEN, INSR, CDK4, CDKN1B, KDR
19	negative regulation of apoptotic process	GO:043066	8.4	TP53, CD44, CDKN1B, VEGFA, KDR, PTEN
20	negative regulation of cell proliferation	GO:008285	8.4	MAP2K1, CDKN2A, CDKN2B, CDKN2C, ETS1, FABP7

Molecular functions related to anaplastic meningioma according to GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	cyclin-dependent protein kinase inhibitor activity	GO:004861	9.6	CDKN2C, CDKN2A, CDKN1B, CDKN2B
2	protein kinase binding	GO:019901	8.8	TP53, CDKN2A, CDKN2B, CDKN2C, VIM, PTEN
3	protein binding	GO:005515	2.9	MMP2, CDK4, CD44, CDH1, NF2, MMP9