MCID: ANP009
MIFTS: 44

Anaplastic Oligodendroglioma malady

Neuronal, Cancer categories

Summaries for Anaplastic Oligodendroglioma

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33MalaCards
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MalaCards: Anaplastic Oligodendroglioma is related to oligoastrocytoma and anaplastic astrocytoma. An important gene associated with Anaplastic Oligodendroglioma is CDKN2C (cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)), and among its related pathways are Cell Cycle and Small cell lung cancer. The compounds estrogen and cycloheximide have been mentioned in the context of this disorder. Affiliated tissues include tongue, spinal cord and brain, and related mouse phenotypes are pigmentation and renal/urinary system.

Aliases & Classifications for Anaplastic Oligodendroglioma

Sources:
43NIH Rare Diseases, 45Novoseek, 49Orphanet, 61UMLS
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer
Anatomical: Neuronal


Characteristics (Orphanet epidemiological data):

49
anaplastic oligodendroglioma:
Inheritance: Sporadic; Age of onset: Adulthood


Aliases & Descriptions:

anaplastic oligodendroglioma 43 45 49 61


Related Diseases for Anaplastic Oligodendroglioma

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Anaplastic Oligodendroglioma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 135)
idRelated DiseaseScoreTop Affiliating Genes
1oligoastrocytoma30.8GFAP, MGMT
2anaplastic astrocytoma30.6CDKN2B, CDKN2A, IGFBP2, EGFR, MDM2, MGMT
3astrocytoma30.6MGMT, PDGFRA, MDM2, EGFR, LGALS3, PTEN
4brain cancer30.5MGMT, MDM2, EGFR
5acute leukemia30.4STMN1, IGFBP2, CDKN2B, CDKN2C
6central neurocytoma30.2GFAP, OLIG2
7cerebral cavernous malformation30.2PTEN, KDR
8acute lymphoblastic leukemia, childhood30.2MDM2, CDKN2A, CDKN2B, CDK4
9pilocytic astrocytoma30.2LGALS3, PTEN, GFAP, OLIG2, CDK4, MGMT
10anaplastic oligoastrocytoma10.6
11brain oligodendroglioma10.5
12spinal cord oligodendroglioma10.4
13childhood oligodendroglioma10.1
14arteriovenous malformation10.1
15acute t cell leukemia10.1
16psoriatic arthritis10.1
17ganglioglioma10.1
18gangliocytoma10.1
19cerebellar liponeurocytoma10.1
20cerebral lymphoma10.1
21arthritis10.1
22t-cell leukemia10.1
23williams syndrome10.1
24anaplastic ganglioglioma10.1
25thunderclap headache10.1
26diffuse astrocytoma10.1
27cavernous malformation10.1
28headache10.1
29cholangiocarcinoma10.0LGALS3
30pituitary tumors10.0LGALS3
31uterine sarcoma10.0MDM2
32neurofibromatosis10.0PDGFRA
33multiple myeloma10.0CDKN2A
34hemangiopericytoma10.0MDM2
35paraganglioma10.0GFAP
36hepatitis10.0IGFBP2
37kidney cancer10.0EGFR
38leiomyoma10.0PDGFRA
39cholesteatoma10.0LGALS3
40neurofibroma10.0PDGFRA
41myeloma10.0CDKN2C, CDKN2B
42chondroma10.0PDGFRA
43mycosis fungoides10.0CDKN2B
44myeloid leukemia10.0CDKN2B, CDK4
45meningitis10.0IGFBP2
46leukoplakia10.0MGMT
47biliary tract cancer10.0EGFR
48parathyroid adenoma10.0LGALS3, CDKN2C
49teratoma10.0GFAP
50fibrosarcoma10.0MDM2, PDGFRA

Graphical network of the top 20 diseases related to Anaplastic Oligodendroglioma:



Diseases related to anaplastic oligodendroglioma

Clinical Features for Anaplastic Oligodendroglioma

Drugs & Therapeutics for Anaplastic Oligodendroglioma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Anaplastic Oligodendroglioma

Drug clinical trials:

Search ClinicalTrials for Anaplastic Oligodendroglioma

Search NIH Clinical Center for Anaplastic Oligodendroglioma

Search CenterWatch for Anaplastic Oligodendroglioma

Genetic Tests for Anaplastic Oligodendroglioma

Anatomical Context for Anaplastic Oligodendroglioma

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Anaplastic Oligodendroglioma:

33
Tongue, Spinal cord, Brain, Bone marrow, Breast, B lymphoblasts, B cells, Endothelial

Animal Models for Anaplastic Oligodendroglioma or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Anaplastic Oligodendroglioma:

37 (show all 23)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000118610.5L1CAM
2MP:000536710.4LGALS3, EGFR
3MP:00053909.9PDGFRA, LGALS3, OLIG2, L1CAM
4MP:00053919.9EGFR, GFAP, L1CAM
5MP:00053769.6GFAP, CDKN2C, PDGFRA, MGMT, STMN1, CDK4
6MP:00053899.5L1CAM, PTEN, PDGFRA, CDKN2B, CDKN2A, EGFR
7MP:00036319.4LGALS3, L1CAM, CDK4, INA, OLIG1, OLIG2
8MP:00053889.4KDR, PTEN, LGALS3, CDKN2C, EGFR, OLIG2
9MP:00053699.4GFAP, OLIG2, CDK4, CDKN2A, STMN1, MDM2
10MP:00107719.3L1CAM, CDK4, CDKN2B, CDKN2A, CDKN2C, PTEN
11MP:00053819.2PTEN, GFAP, CDK4, CDKN2A, EGFR, MDM2
12MP:00053799.2CDK4, PDGFRA, MGMT, CDKN2A, CDKN2B, CDKN2C
13MP:00053709.2PTEN, IGFBP2, KDR, CDK4, EGFR, MDM2
14MP:00030129.1OLIG2, CDKN2B, EGFR, MDM2, MGMT, KDR
15MP:00020069.1CDKN2C, CDK4, CDKN2B, CDKN2A, PDGFRA, MGMT
16MP:00053978.8CDKN2B, CDK4, CDKN2C, KDR, PTEN, LGALS3
17MP:00053858.8PTEN, KDR, GFAP, CDKN2C, CDK4, IGFBP2
18MP:00028738.8GFAP, INA, EGFR, STMN1, PDGFRA, IGFBP2
19MP:00053878.7CDKN2A, LGALS3, PDGFRA, MDM2, EGFR, IGFBP2
20MP:00053868.6GFAP, MDM2, PTEN, KDR, OLIG2, CDKN2C
21MP:00053848.5MDM2, EGFR, CDKN2A, CDKN2B, L1CAM, CDKN2C
22MP:00053788.5CDKN2A, CDK4, OLIG1, OLIG2, CDKN2C, PTEN
23MP:00107688.1OLIG2, OLIG1, CDKN2C, CDK4, CDKN2B, CDKN2A

Publications for Anaplastic Oligodendroglioma

Sources:
51PubMed
See all sources

Articles related to Anaplastic Oligodendroglioma:

(show top 50)    (show all 111)
idTitleAuthorsYear
1
Health-related quality of life and cognitive functioning in long-term anaplastic oligodendroglioma and oligoastrocytoma survivors. (24162809)
2014
2
Pitfalls of conservative treatments of multiple probable cerebral cavernous malformations (CCMs): clinicopathological features of CCMs coexisting with vasculogenic mimicry in an anaplastic oligodendroglioma. (24337536)
2013
3
Erratum to: Leukemia-like onset of bone marrow metastasis from anaplastic oligodendroglioma after 17A years of dormancy: an autopsy case report. (24036579)
2013
4
Feline anaplastic oligodendroglioma: long-term remission through radiation therapy and chemotherapy. (23651604)
2013
5
Minding the Ps and Qs: perseverance and quality studies lead to major advances in patients with anaplastic oligodendroglioma. (23071223)
2013
6
Extraneural metastases of anaplastic oligodendroglioma. (24373094)
2013
7
New clinical, pathological and molecular prognostic models and calculators in patients with locally diagnosed anaplastic oligodendroglioma or oligoastrocytoma. A prognostic factor analysis of European Organisation for Research and Treatment of Cancer Brain Tumour Group Study 26951. (23896377)
2013
8
Diffuse anaplastic leptomeningeal oligodendrogliomatosis mimicking neurosarcoidosis. (23914328)
2013
9
A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1. (23527265)
2013
10
Anaplastic oligodendroglioma: a new treatment paradigm and current controversies. (23907441)
2013
11
Anaplastic oligodendroglioma: advances and treatment options. (23344797)
2013
12
Long-term survival in a dog with anaplastic oligodendroglioma treated with radiation therapy and CCNU. (22785244)
2012
13
Breast metastasis of anaplastic oligodendroglioma: a case report. (23389376)
2012
14
Pleomorphic xanthoastrocytoma and oligodendroglioma: collision of 2 morphologically and genetically distinct anaplastic components. (21214337)
2011
15
Extracranial metastases of anaplastic oligodendroglioma. (20888774)
2011
16
Spinal cord anaplastic oligodendroglioma with 1p deletion: report of a relapsing case treated with temozolomide. (21190059)
2011
17
Synchronous anaplastic oligodendroglioma and carcinoma tongue: a rare association. (20622375)
2010
18
Collision tumor of anaplastic oligodendroglioma and gangliocytoma: a case report. (19856221)
2009
19
Anaplastic intraventricular oligodendroglioma: case report and review of the literature. (18291495)
2009
20
Complete Radiologic Response in an Anaplastic Oligodendroglioma Treated with Temozolomide and Bevacizumab. (20740146)
2009
21
Gene amplification is a poor prognostic factor in anaplastic oligodendrogliomas. (18544654)
2008
22
Anaplastic oligodendroglioma with meningeal infiltration in a free-ranging red deer (Cervus elaphus). (17983625)
2008
23
De novo formation of large arteriovenous shunting and a vascular nidus mimicking an arteriovenous malformation within an anaplastic oligodendroglioma: treatment with embolization and resection. (19035725)
2008
24
Extraneural metastases of anaplastic oligodendroglioma. (18280737)
2008
25
CPT-11 for recurrent temozolomide-refractory 1p19q co-deleted anaplastic oligodendroglioma. (18480965)
2008
26
A phase II study of intensified chemotherapy alone as initial treatment for newly diagnosed anaplastic oligodendroglioma: an interim analysis. (18458821)
2008
27
Anaplastic oligodendroglioma after childhood acute lymphoblastic leukemia: chemotherapy and autologous peripheral blood stem cell transplantation. (19011476)
2008
28
Anaplastic astrocytoma and anaplastic oligodendroglioma occurring 6 years after subtotal resection of a central neurocytoma. Case report. (17639893)
2007
29
Frontal anaplastic oligodendroglioma showing multi-organ metastases after a long clinical course. Case report. (17457022)
2007
30
Thunderclap headache associated with a nonhemorrhagic anaplastic oligodendroglioma. (18092032)
2007
31
Anaplastic mixed gliomas and anaplastic oligodendroglioma in children: results from the CCG 945 experience. (17252186)
2007
32
Anaplastic oligodendroglioma responding favorably to intranasal delivery of perillyl alcohol: a case report and literature review. (17145324)
2006
33
Phase III trial of chemotherapy plus radiotherapy compared with radiotherapy alone for pure and mixed anaplastic oligodendroglioma: Intergroup Radiation Therapy Oncology Group Trial 9402. (16782910)
2006
34
Anaplastic oligodendroglioma presenting with drop metastases in the cauda equina. (16023538)
2005
35
MR Imaging in anaplastic oligodendroglioma. (16078116)
2005
36
Clinical and radiological prognostic factors of anaplastic oligodendroglioma treated by combined therapy. (15914962)
2005
37
Efficacy and feasibility of procarbazine, ranimustine and vincristine chemotherapy, and the role of surgical resection in anaplastic oligodendroglioma. (16302731)
2005
38
Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas. (15289301)
2004
39
Efficacy and feasibility of standard procarbazine, lomustine, and vincristine chemotherapy in anaplastic oligodendroglioma and oligoastrocytoma recurrent after radiotherapy. A Phase II study. (15372474)
2004
40
Importance of immunohistochemical staining in metastatic anaplastic oligodendroglioma. (15043478)
2004
41
Role of intraoperative smear cytology in the diagnosis of anaplastic oligodendroglioma. A case report. (12685204)
2003
42
High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma. (14686732)
2003
43
Anaplastic oligodendroglioma with metastasis to the spinal cord. (14579906)
2003
44
B cell non-Hodgkin cerebral lymphoma associated with an anaplastic oligodendroglioma. (12489671)
2002
45
Anaplastic oligodendroglioma with drop metastasis to the spinal cord. (12140111)
2002
46
Case for the panel. Crystalline cytoplasmic inclusions in an anaplastic oligodendroglioma. (11206340)
2000
47
Expression of vascular endothelial growth factor and its receptors in the anaplastic progression of astrocytoma, oligodendroglioma, and ependymoma. (9669344)
1998
48
Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. (9776413)
1998
49
Pancytopaenia from a disseminated anaplastic oligodendroglioma. (9460719)
1997
50
Is there an anaplastic type of oligodendroglioma? A case report. (61266)
1976

Genetic Variations for Anaplastic Oligodendroglioma

Expression for genes affiliated with Anaplastic Oligodendroglioma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Anaplastic Oligodendroglioma

Search GEO for disease gene expression data for Anaplastic Oligodendroglioma.

Pathways for genes affiliated with Anaplastic Oligodendroglioma

Sources:
54Reactome, 30KEGG, 12EMD Millipore, 38NCBI BioSystems Database, 50PharmGKB, 60Tocris Bioscience, 52QIAGEN, 4Cell Signaling Technology, 53R&D Systems
See all sources

Pathways related to Anaplastic Oligodendroglioma according to GeneCards/GeneDecks:

(show all 37)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
10.2DBF4
210.0CDK4, CDKN2B, PTEN
3
Transcription Androgen Receptor nuclear signaling
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9.9PTEN, MDM2, EGFR
49.9PTEN, EGFR, MDM2
5
Hide members
9.9KDR, PDGFRA, EGFR
6
Hide members
9.9MDM2, IGFBP2, PTEN
7
Hide members
9.9CDKN2C, CDKN2B, MDM2, PDGFRA
8
Hide members
9.9CDKN2C, CDKN2B, CDK4, CDKN2A
9
Hide members
9.9STMN1, CDKN2B, CDK4, PDGFRA
10
Hide members
9.9L1CAM, EGFR, KDR
119.8MDM2, CDK4, CDKN2B, CDKN2A
12
Hide members
9.8CDKN2A, PTEN, CDK4, MDM2
139.8GFAP, OLIG2, OLIG1
14
Transcription P53 signaling pathway
Hide members
9.8CDKN2A, KDR, CDK4, MDM2
159.8MDM2, PTEN, CDK4, EGFR
169.8EGFR, LGALS3, CDK4, GFAP
17
Hide members
9.8EGFR, CDK4, MDM2, CDKN2A
18
Hide members
9.8EGFR, MDM2, PDGFRA, PTEN
19
Hide members
9.8EGFR, MDM2, PDGFRA, PTEN
209.8PDGFRA, MDM2, EGFR, KDR
21
Hide members
9.8PDGFRA, KDR, EGFR, MDM2
22
Hide members
9.7KDR, PDGFRA, EGFR, PTEN
23
Hide members
9.7DBF4, MDM2, CDKN2A, CDKN2C
249.7PDGFRA, CDKN2B, CDK4, CDKN2C, CDKN2A
25
Hide members
9.6CDKN2C, CDKN2A, MDM2, CDK4, MGMT
26
Hide members
9.6EGFR, KDR, MDM2, PDGFRA, PTEN
27
Hide members
9.6KDR, PDGFRA, MDM2, EGFR, PTEN
28
Hide members
9.6PTEN, EGFR, MDM2, GFAP, PDGFRA
299.4PTEN, CDKN2A, EGFR, MDM2, PDGFRA, STMN1
309.4PTEN, KDR, CDK4, MDM2, PDGFRA, EGFR
319.4EGFR, CDK4, MDM2, PTEN, PDGFRA, KDR
32
Hide members
9.4CDKN2C, MDM2, CDKN2A, CDK4, CDKN2B, DBF4
33
Hide members
9.4PTEN, MDM2, KDR, CDKN2A, EGFR, PDGFRA
349.3MDM2, PTEN, CDK4, CDKN2B, EGFR, STMN1
359.3CDKN2B, MDM2, EGFR, CDKN2A, PTEN, CDK4
369.2MGMT, PTEN, PDGFRA, MDM2, EGFR, CDKN2A
37
Hide members
8.6CDKN2A, CDKN2B, PDGFRA, MDM2, PTEN, KDR

Compounds for genes affiliated with Anaplastic Oligodendroglioma

Sources:
45Novoseek, 11DrugBank, 50PharmGKB, 60Tocris Bioscience, 24HMDB, 29IUPHAR, 2BitterDB
See all sources

Compounds related to Anaplastic Oligodendroglioma according to GeneCards/GeneDecks:

(show top 50)    (show all 105)
idCompoundScoreTop Affiliating Genes
1estrogen4510.7GFAP
2cycloheximide4510.6IGFBP2
3serine4510.3STMN1, CDKN2B, CDKN2C, GFAP
4bcnu4510.1EGFR, MGMT, CDKN2A, GFAP
5sodium bisulfite4510.1MGMT, CDKN2B, CDKN2A
6flavopiridol45 1111.0CDK4, CDKN2A, EGFR, MDM2
7hematoxylin4510.0LGALS3, CDKN2A, GFAP, PTEN
8tgf beta14510.0CDKN2B, PTEN, KDR, CDK4, PDGFRA
9trastuzumab45 50 1112.0EGFR, MDM2, KDR, PTEN, CDK4
107,12-dimethylbenz(a)anthracene4510.0MDM2, CDKN2A, MGMT
11gefitinib45 50 1112.0CDK4, KDR, EGFR, MDM2, PTEN
12deoxyribonucleic acid4510.0IGFBP2, PTEN, CDKN2A, MGMT
13camptothecin45 60 1112.0MGMT, CDKN2A, MDM2, CDK4, KDR
14carboplatin45 50 1112.0MGMT, KDR, CDK4, EGFR, MDM2
15thymidylate4510.0MGMT, CDKN2A, EGFR, CDK4, MDM2
16mg 13245 6010.9MDM2, KDR, PTEN, CDKN2A, EGFR
17imatinib45 50 1111.9EGFR, KDR, PDGFRA, PTEN, MDM2
185-aza-2deoxycytidine459.9MGMT, MDM2, CDKN2A, CDKN2B, PTEN
19irinotecan45 50 1111.9MGMT, MDM2, EGFR, CDKN2A
20ly294002459.9IGFBP2, CDK4, MDM2, EGFR, KDR
21folate459.8KDR, PDGFRA, MGMT, IGFBP2, CDKN2A
22glyceraldehyde 3-phosphate459.8GFAP, LGALS3, STMN1, IGFBP2, MDM2
23glycogen45 2410.7PTEN, MDM2, IGFBP2, GFAP, CDK4, LGALS3
24pd 98,059459.7PTEN, GFAP, CDK4, CDKN2B, EGFR, MDM2
25progestin459.7KDR, CDK4, IGFBP2, EGFR
265-methylcytosine45 2410.7MGMT, CDKN2B, CDKN2A
275fluorouracil459.6KDR, CDK4, CDKN2A, EGFR, MDM2, MGMT
28phosphotyrosine459.6PTEN, CDK4, EGFR, PDGFRA, KDR
29dexamethasone45 50 29 1112.6MDM2, MGMT, CDK4, CDKN2A, KDR, GFAP
30rapamycin459.6PTEN, PDGFRA, KDR, EGFR, MDM2, IGFBP2
31agar459.5LGALS3, PTEN, MDM2, EGFR, CDKN2A, CDK4
32paclitaxel45 50 1111.5PTEN, KDR, GFAP, CDK4, MDM2, CDKN2A
33calcium45 50 11 2412.5STMN1, LGALS3, IGFBP2, CDK4, INA, GFAP
34doxorubicin45 50 1111.5MDM2, MGMT, STMN1, EGFR, CDKN2A, CDK4
35threonine459.5CDKN2B, STMN1, CDK4, GFAP, CDKN2C, PTEN
36genistein45 29 60 2 11 2414.4CDK4, PTEN, KDR, GFAP, CDKN2A, EGFR
37testosterone45 60 11 2412.4MDM2, EGFR, IGFBP2, CDKN2A, CDK4, GFAP
38thymidine45 2410.4GFAP, MGMT, MDM2, STMN1, IGFBP2, CDK4
39arginine459.4LGALS3, PTEN, CDK4, KDR, IGFBP2, GFAP
40phosphatidylinositol459.4IGFBP2, EGFR, MDM2, PDGFRA, KDR, PTEN
41oxygen45 2410.4LGALS3, PTEN, MDM2, CDKN2A, IGFBP2, STMN1
42cysteine459.3CDK4, MGMT, PTEN, GFAP, CDKN2A, MDM2
43oligonucleotide459.3LGALS3, PTEN, CDK4, CDKN2A, IGFBP2, STMN1
44nitric oxide45 11 2411.2MDM2, MGMT, KDR, CDKN2A, PTEN, LGALS3
45cisplatin45 50 60 1112.2PTEN, GFAP, LGALS3, CDK4, CDKN2A, EGFR
46paraffin459.2EGFR, CDKN2A, CDK4, GFAP, MDM2, KDR
47progesterone45 60 29 11 2413.1MDM2, STMN1, EGFR, IGFBP2, CDK4, GFAP
48vegf458.9IGFBP2, EGFR, LGALS3, CDKN2A, CDK4, GFAP
49tyrosine458.7L1CAM, PDGFRA, MDM2, STMN1, IGFBP2, CDKN2B
50retinoic acid45 249.3CDKN2B, OLIG2, INA, CDK4, CDKN2A, IGFBP2

GO Terms for genes affiliated with Anaplastic Oligodendroglioma

Sources:
16Gene Ontology
See all sources

Cellular components related to Anaplastic Oligodendroglioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytoplasmGO:0057378.4MDM2, EGFR, TRIM8, CDKN2A, CDKN2B, CDKN2C
2nucleusGO:0056347.6LGALS3, PDGFRA, MGMT, MDM2, EGFR, TRIM8

Biological processes related to Anaplastic Oligodendroglioma according to GeneCards/GeneDecks:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1G1/S transition of mitotic cell cycleGO:00008210.4DBF4
2negative regulation of phosphorylationGO:04232610.3CDKN2A, CDKN2B, CDKN2C
3positive regulation of fibroblast proliferationGO:04814610.2PDGFRA, EGFR, CDK4
4regulation of cyclin-dependent protein serine/threonine kinase activityGO:00007910.2CDKN2B, CDKN2C, PTEN
5phosphatidylinositol-mediated signalingGO:04801510.0PTEN, EGFR, MDM2, PDGFRA
6fibroblast growth factor receptor signaling pathwayGO:00854310.0PTEN, EGFR, MDM2, PDGFRA
7Fc-epsilon receptor signaling pathwayGO:0380959.9PTEN, EGFR, MDM2, PDGFRA
8epidermal growth factor receptor signaling pathwayGO:0071739.8PDGFRA, MDM2, EGFR, PTEN
9mitotic cell cycleGO:0002789.8DBF4, CDKN2A, CDKN2B, CDK4, CDKN2C
10response to drugGO:0424939.7MGMT, MDM2, IGFBP2, CDK4
11positive regulation of cell proliferationGO:0082849.7PTEN, KDR, CDK4, EGFR, MDM2, PDGFRA
12neurotrophin TRK receptor signaling pathwayGO:0480119.7PTEN, EGFR, MDM2, PDGFRA
13innate immune responseGO:0450879.6LGALS3, PTEN, EGFR, MDM2, PDGFRA
14positive regulation of ERK1 and ERK2 cascadeGO:0703749.6PDGFRA, EGFR, KDR

Molecular functions related to Anaplastic Oligodendroglioma according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1vascular endothelial growth factor bindingGO:03808510.2KDR, PDGFRA
2cyclin-dependent protein serine/threonine kinase inhibitor activityGO:00486110.2CDKN2C, CDKN2B, CDKN2A
3vascular endothelial growth factor-activated receptor activityGO:00502110.1KDR, PDGFRA
4transmembrane receptor protein tyrosine kinase activityGO:00471410.0KDR, EGFR, PDGFRA
5receptor signaling protein tyrosine kinase activityGO:00471610.0EGFR, KDR
6protein kinase bindingGO:0199019.8CDKN2C, CDKN2B, CDKN2A, PTEN
7integrin bindingGO:0051789.6KDR, GFAP, L1CAM

Products for genes affiliated with Anaplastic Oligodendroglioma

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Anaplastic Oligodendroglioma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet