MCID: ANM038
MIFTS: 56

Anemia, Autoimmune Hemolytic

Categories: Rare diseases, Blood diseases, Metabolic diseases, Immune diseases, Genetic diseases

Aliases & Classifications for Anemia, Autoimmune Hemolytic

MalaCards integrated aliases for Anemia, Autoimmune Hemolytic:

Name: Anemia, Autoimmune Hemolytic 53
Autoimmune Hemolytic Anemia 12 72 49 36 28 51 14 69
Idiopathic Autoimmune Hemolytic Anemia 49 69
Immuno-Hemolytic Anemia 49 69
Familial Auto-Immune Hemolytic Anemia 49
Acquired Autoimmune Hemolytic Anemia 49
Autoimmune Hemolytic Anemia Nos 12
Autoimmune Haemolytic Anaemia 12
Anemia, Hemolytic, Autoimmune 41
Anemia Hemolytic Autoimmune 49

Characteristics:

OMIM:

53
Inheritance:
autosomal recessive


HPO:

31
anemia, autoimmune hemolytic:
Inheritance autosomal recessive inheritance


Classifications:



Summaries for Anemia, Autoimmune Hemolytic

NIH Rare Diseases : 49 Autoimmune hemolytic anemia (AIHA) occurs when your immune system makes antibodies that attack your red blood cells. This causes a drop in the number of red blood cells, leading to hemolytic anemia. Symptoms may include unusual weakness and fatigue with tachycardia and breathing difficulties, jaundice, dark urine and/or splenomegaly. AIHA can be primary (idiopathic) or result from an underlying disease or medication. The condition may develop gradually or occur suddenly. There are two main types of autoimmune hemolytic anemia: warm antibody hemolytic anemia and cold antibody hemolytic anemia. Treatment may include corticosteroids such as prednisone, splenectomy, immunosuppressive drugs and/or blood transfusions. Last updated: 3/9/2016

MalaCards based summary : Anemia, Autoimmune Hemolytic, also known as autoimmune hemolytic anemia, is related to evans' syndrome and drug-induced autoimmune hemolytic anemia, and has symptoms including fatigue, dyspnea and fever. An important gene associated with Anemia, Autoimmune Hemolytic is HP (Haptoglobin), and among its related pathways/superpathways are Creation of C4 and C2 activators and Complement and coagulation cascades. The drugs Methylprednisolone and Prednisolone have been mentioned in the context of this disorder. Affiliated tissues include heart, and related phenotype is hematopoietic system.

Disease Ontology : 12 An autoimmune disease of blood that is characterized by deficient red blood cells caused by auto-antibodies.

Wikipedia : 72 Autoimmune hemolytic anemia (or autoimmune haemolytic anaemia; AIHA) occurs when antibodies directed... more...

Description from OMIM: 205700

Related Diseases for Anemia, Autoimmune Hemolytic

Diseases in the Hemolytic Anemia family:

Anemia, Autoimmune Hemolytic Congenital Hemolytic Anemia
Hemolytic Anemia Due to Erythrocyte Adenosine Deaminase Overproduction

Diseases related to Anemia, Autoimmune Hemolytic via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 151)
# Related Disease Score Top Affiliating Genes
1 evans' syndrome 33.2 CD40LG HP
2 drug-induced autoimmune hemolytic anemia 12.3
3 mixed-type autoimmune hemolytic anemia 12.3
4 autoimmune hemolytic anemia, warm type 12.3
5 lymphopenic hypergammaglobulinemia, antibody deficiency, autoimmune hemolytic anemia, and glomerulonephritis 12.1
6 neonatal autoimmune hemolytic anemia 12.1
7 autoimmune hemolytic anemia-autoimmune thrombocytopenia-primary immunodeficiency syndrome 12.1
8 warm antibody hemolytic anemia 11.9
9 cold agglutinin disease 11.5
10 purine nucleoside phosphorylase deficiency 11.4
11 hemolytic anemia 10.6
12 selective igg deficiency disease 10.5 CD40LG CD79A
13 c1q nephropathy 10.5 CD40LG CD79A
14 meningovascular neurosyphilis 10.5 CD40LG CD79A
15 alpha chain disease 10.5 CD40LG CD79A
16 brill-zinsser disease 10.5 CD40LG CD79A
17 exudative glomerulonephritis 10.5 CD40LG CD79A
18 cork-handlers' disease 10.5 CD40LG CD79A
19 salpingo-oophoritis 10.5 CD40LG CD79A
20 early yaws 10.5 CD40LG CD79A
21 ventilation pneumonitis 10.5 CD40LG CD79A
22 chronic interstitial cystitis 10.5 CD40LG CD79A
23 axillary adenitis 10.5 CD40LG CD79A
24 trichostrongyloidiasis 10.5 CD40LG CD79A
25 subacute bacterial endocarditis 10.5 CD40LG CD79A
26 heterophyiasis 10.5 CD40LG CD79A
27 immunoglobulin g deficiency 10.5 CD40LG CD79A
28 orbital granuloma 10.5 CD40LG CD79A
29 transient hypogammaglobulinemia of infancy 10.5 CD40LG CD79A
30 hyperglobulinemic purpura 10.5 CD40LG CD79A
31 gastroduodenitis 10.5 CD40LG CD79A
32 bacterial conjunctivitis 10.5 CD40LG CD79A
33 heavy chain disease 10.5 CD40LG CD79A
34 ophthalmia neonatorum 10.5 CD40LG CD79A
35 immunoglobulin a deficiency 1 10.5 CD40LG CD79A
36 parotid disease 10.5 CD40LG CD79A
37 cerebral arteritis 10.5 CD40LG CD79A
38 selective immunoglobulin deficiency disease 10.5 CD40LG CD79A
39 multiple congenital anomalies-hypotonia-seizures syndrome 2 10.5 CD55 CD59
40 erythema elevatum diutinum 10.5 CD40LG CD79A
41 sporotrichosis 10.5 CD40LG CD79A
42 fallopian tube disease 10.5 CD40LG CD79A
43 hyperimmunoglobulin syndrome 10.5 CD40LG CD79A
44 congenital syphilis 10.5 CD40LG CD79A
45 polyclonal hypergammaglobulinemia 10.5 CD40LG CD79A
46 monoclonal paraproteinemia 10.5 CD40LG CD79A
47 salpingitis 10.5 CD40LG CD79A
48 ocular toxoplasmosis 10.5 CD40LG CD79A
49 parasitic ichthyosporea infectious disease 10.5 CD40LG CD79A
50 dysgammaglobulinemia 10.5 CD40LG CD79A

Comorbidity relations with Anemia, Autoimmune Hemolytic via Phenotypic Disease Network (PDN):


Acquired Thrombocytopenia Acute Cystitis
Deficiency Anemia Familial Atrial Fibrillation
Heart Disease Leukemia, Chronic Lymphocytic
Neutropenia

Graphical network of the top 20 diseases related to Anemia, Autoimmune Hemolytic:



Diseases related to Anemia, Autoimmune Hemolytic

Symptoms & Phenotypes for Anemia, Autoimmune Hemolytic

Symptoms via clinical synopsis from OMIM:

53
Heme:
autoimmune hemolytic anemia

Lab:
coombs positive
abnormal immunoglobulin in heterozygotes


Clinical features from OMIM:

205700

Human phenotypes related to Anemia, Autoimmune Hemolytic:

31 (show all 18)
# Description HPO Frequency HPO Source Accession
1 fatigue 31 hallmark (90%) HP:0012378
2 dyspnea 31 hallmark (90%) HP:0002094
3 fever 31 occasional (7.5%) HP:0001945
4 headache 31 hallmark (90%) HP:0002315
5 abdominal pain 31 occasional (7.5%) HP:0002027
6 muscle weakness 31 hallmark (90%) HP:0001324
7 splenomegaly 31 occasional (7.5%) HP:0001744
8 abnormality of metabolism/homeostasis 31 HP:0001939
9 arrhythmia 31 occasional (7.5%) HP:0011675
10 immunodeficiency 31 frequent (33%) HP:0002721
11 hemolytic anemia 31 hallmark (90%) HP:0001878
12 pallor 31 frequent (33%) HP:0000980
13 congestive heart failure 31 occasional (7.5%) HP:0001635
14 autoimmunity 31 hallmark (90%) HP:0002960
15 lymphoma 31 frequent (33%) HP:0002665
16 abnormal urinary color 31 occasional (7.5%) HP:0012086
17 autoimmune hemolytic anemia 31 HP:0001890
18 abnormal leukocyte morphology 31 hallmark (90%) HP:0001881

MGI Mouse Phenotypes related to Anemia, Autoimmune Hemolytic:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.28 C3 CD40LG CD5 CD55 CD59 CD79A

Drugs & Therapeutics for Anemia, Autoimmune Hemolytic

Drugs for Anemia, Autoimmune Hemolytic (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 71)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methylprednisolone Approved, Vet_approved Phase 3,Phase 2 83-43-2 6741
2
Prednisolone Approved, Vet_approved Phase 3,Phase 2 50-24-8 5755
3
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
4
rituximab Approved Phase 3,Phase 2 174722-31-7 10201696
5
Fludarabine Approved Phase 3,Phase 2 21679-14-1, 75607-67-9 30751
6
Vidarabine Approved, Investigational Phase 3,Phase 2 24356-66-9 21704 32326
7
Chlorambucil Approved Phase 3 305-03-3 2708
8 Antirheumatic Agents Phase 3,Phase 2
9 Antibodies Phase 3,Phase 2
10 Antiemetics Phase 3,Phase 2
11 Anti-Inflammatory Agents Phase 3,Phase 2
12 Antineoplastic Agents, Hormonal Phase 3,Phase 2
13 Autonomic Agents Phase 3,Phase 2
14 Gastrointestinal Agents Phase 3,Phase 2
15 glucocorticoids Phase 3,Phase 2
16 Hormone Antagonists Phase 3,Phase 2
17 Hormones Phase 3,Phase 2
18 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2
19 Immunoglobulins Phase 3,Phase 2
20 Methylprednisolone acetate Phase 3,Phase 2
21 Methylprednisolone Hemisuccinate Phase 3,Phase 2
22 Neuroprotective Agents Phase 3,Phase 2
23 Peripheral Nervous System Agents Phase 3,Phase 2,Phase 1
24 Prednisolone acetate Phase 3,Phase 2
25 Prednisolone hemisuccinate Phase 3,Phase 2
26 Prednisolone phosphate Phase 3,Phase 2
27 Protective Agents Phase 3,Phase 2
28 Alkylating Agents Phase 3,Phase 2
29 Anti-Infective Agents Phase 3,Phase 2,Phase 1
30 Immunosuppressive Agents Phase 3,Phase 2
31 Antibodies, Monoclonal Phase 3,Phase 2
32 Antimetabolites Phase 3,Phase 2
33 Antimetabolites, Antineoplastic Phase 3,Phase 2
34 Antiviral Agents Phase 3,Phase 2,Phase 1
35
Prednisone Approved, Vet_approved Phase 2 53-03-2 5865
36
Lenograstim Approved, Investigational Phase 2 135968-09-1
37
Doxorubicin Approved, Investigational Phase 2 23214-92-8 31703
38
Vincristine Approved, Investigational Phase 2 2068-78-2, 57-22-7 5978
39
Mechlorethamine Approved, Investigational Phase 2 51-75-2 4033
40
Aldesleukin Approved Phase 1, Phase 2 110942-02-4, 85898-30-2
41
alemtuzumab Approved, Investigational Phase 2 216503-57-0
42
Doxil Approved June 1999 Phase 2 31703
43
Lactitol Investigational Phase 1, Phase 2 585-86-4 3871
44 Adjuvants, Immunologic Phase 2
45 Anthelmintics Phase 2
46 Antiparasitic Agents Phase 2
47 Autoantibodies Phase 2
48 Anti-Bacterial Agents Phase 2
49 Antibiotics, Antitubercular Phase 2
50 Antimitotic Agents Phase 2

Interventional clinical trials:

(show all 26)

# Name Status NCT ID Phase Drugs
1 Rituximab in Auto-Immune Hemolytic Anemia Completed NCT01181154 Phase 3 rituximab (Mabthera®);Placebo
2 Prednisolone +/- Addition of Anti-CD20 Antibody, Rituximab, in Patients With Immune Hemolytic Anemia Completed NCT01134432 Phase 3 prednisolone + mabthera;Prednisolone
3 Ofatumumab Added to Fludarabine-Cyclophosphamide vs Fludarabine-Cyclophosphamide Combination in Relapsed Subjects With Chronic Lymphocytic Leukemia Completed NCT00824265 Phase 3 OFC Infusion;FC infusion
4 Ofatumumab + Chlorambucil vs Chlorambucil Monotherapy in Previously Untreated Patients With Chronic Lymphocytic Leukemia Active, not recruiting NCT00748189 Phase 3 chlorambucil, tablets;ofatumumab (GSK1841157) infusion
5 Ofatumumab Maintenance Treatment vs No Further Treatment in Relapsed CLL Responding to Induction Therapy Active, not recruiting NCT01039376 Phase 3
6 Efficacy and Safety of Levamisole Combined With Standard Prednisolone in Warm Antibody Autoimmune Hemolytic Anemia. Unknown status NCT01579110 Phase 2 levamisole;Prednisone
7 A Single-Arm Pilot Study With Low-Dose Rituximab Plus Standard Oral Prednisone In Idiopathic Autoimmune Hemolytic Anemia Completed NCT01345708 Phase 2 prednisone, low dose rituximab
8 Combination Chemotherapy and Rituximab in Treating Patients With Chronic Lymphocytic Leukemia (CLL) That Did Not Respond to Fludarabine, CLL With Autoimmune Haemolytic Anemia (AIHA) or Richter's Transformation (RT) Completed NCT00309881 Phase 2 cyclophosphamide;doxorubicin hydrochloride;prednisone;vincristine sulfate
9 Bendamustine and Rituximab Combination Therapy for Cold Agglutinin Disease Completed NCT02689986 Phase 2 Bendamustine, Rituximab
10 Therapy for Chronic Cold Agglutinin Disease Completed NCT00373594 Phase 2 Rituximab;Fludarabine
11 Phase II Study of High-Dose Cyclophosphamide in Patients With Severe Autoimmune Hematologic Disease Completed NCT00010387 Phase 2 cyclophosphamide;filgrastim
12 Ofatumumab Plus Bendamustine in Frontline and Relapsed Chronic Lymphocytic Leukaemia (CLL) Completed NCT01520922 Phase 2 Bendamustine
13 A Safety and Efficacy Study of R935788 in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia (AIHA) Recruiting NCT02612558 Phase 2 Fostamatinib 150 mg bid
14 Study to Assess the Safety, Tolerability, Efficacy and PK of APL-2 in Patients With wAIHA or CAD Recruiting NCT03226678 Phase 2 APL-2
15 Evaluating the Interest of Interleukine-2 for Patients With Active Warm Hemolytic Anemia Resistant to Conventional Treatment Recruiting NCT02389231 Phase 1, Phase 2 Interleukine-2
16 The Efficacy and Safety of Alemtuzumab in Auotoimmune Cytopenias Terminated NCT00472433 Phase 2 Alemtuzumab
17 Treatment of Autoimmune Thrombocytopenia (AITP) Completed NCT00001630 Phase 1
18 A Safety Study of SYNT001 in Subjects With Chronic, Stable Warm Autoimmune Hemolytic Anemia (WAIHA) Recruiting NCT03075878 Phase 1 SYNT001
19 Safety, Tolerability and Activity of TNT009 in Healthy Volunteers and Patients With Complement Mediated Disorders Recruiting NCT02502903 Phase 1 TNT009
20 Immunopathology of Autoimmune Hemolytic Anemia Unknown status NCT02158195
21 Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases Unknown status NCT00006055 anti-thymocyte globulin;cyclophosphamide;cyclosporine;filgrastim;methylprednisolone;prednisone
22 Auto-antibodies Prevalence and CD1 Role in Gaucher Disease Completed NCT02650219
23 The RITAI Cohort: An Observational Study on Rituximab Off-label Use for Auto-immune Disorders Completed NCT00960713 Rituximab (MABTHERA® or RITUXAN®).
24 Study Assessing Risk of Autoimmune Diseases in Females (9 - 25 Years) Exposed to Cervarix® in United Kingdom Completed NCT01953822
25 Study the Role of T Lymphocytes in Autoimmune Hemolytic Anemia Recruiting NCT02828670
26 One Year Hospital Data Patients With AIHA in Assiut University Hospital - Clinical Hematology Unit Not yet recruiting NCT03269292

Search NIH Clinical Center for Anemia, Autoimmune Hemolytic

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: anemia, hemolytic, autoimmune

Genetic Tests for Anemia, Autoimmune Hemolytic

Genetic tests related to Anemia, Autoimmune Hemolytic:

# Genetic test Affiliating Genes
1 Autoimmune Hemolytic Anemia 28

Anatomical Context for Anemia, Autoimmune Hemolytic

MalaCards organs/tissues related to Anemia, Autoimmune Hemolytic:

38
Heart

Publications for Anemia, Autoimmune Hemolytic

Articles related to Anemia, Autoimmune Hemolytic:

(show top 50) (show all 664)
# Title Authors Year
1
Successful treatment of refractory autoimmune hemolytic anemia after allogeneic hematopoietic stem cell transplantation with bortezomib. ( 29345206 )
2018
2
Exacerbation of autoimmune hemolytic anemia induced by the first dose of programmed death-1 inhibitor pembrolizumab: a case report. ( 29340837 )
2018
3
Durable responses in refractory autoimmune hemolytic anemia with alemtuzumab. ( 29334337 )
2018
4
Should Giant Cell Hepatitis With Autoimmune Hemolytic Anemia Be Considered a Pediatric Autoimmune Liver Disease? ( 29394216 )
2018
5
Ominous comorbidities: Small ventricular septal defect and warm autoimmune hemolytic anemia. ( 29440848 )
2018
6
Simultaneous early-onset severe autoimmune hemolytic anemia and albuminuria during alemtuzumab treatment for multiple sclerosis. ( 29359617 )
2018
7
Autoimmune hemolytic anemia in solid organ transplantation-The role of immunosuppression. ( 28621877 )
2017
8
Therapeutic plasma exchange in refractory warm autoimmune hemolytic anemia. ( 28594138 )
2017
9
Platelet satellitism in autoimmune hemolytic anemia. ( 28619392 )
2017
10
Steroid-Refractory Autoimmune Hemolytic Anemia with Massive Splenomegaly. ( 28389309 )
2017
11
Induction of IL-10 cytokine and the suppression of T cell proliferation by specific peptides from red cell band 3 and in vivo effects of these peptides on autoimmune hemolytic anemia in NZB mice. ( 28455817 )
2017
12
Reliable assessment of the incidence of childhood autoimmune hemolytic anemia. ( 28748541 )
2017
13
Tumor necrosis factor gene polymorphisms in adult patients with autoimmune hemolytic anemia. ( 28111935 )
2017
14
Post-Babesiosis Warm Autoimmune Hemolytic Anemia. ( 28273010 )
2017
15
Treatment of chronic lymphocytic leukemia/small lymphocytic lymphoma presenting simultaneously with acquired hemophilia and warm autoimmune hemolytic anemia. ( 28670081 )
2017
16
Autoimmune hemolytic anemia associated with babesiosis. ( 28405337 )
2017
17
Treatment of refractory autoimmune hemolytic anemia with venetoclax in relapsed chronic lymphocytic leukemia with del(17p). ( 28597168 )
2017
18
Autoimmune Hemolytic Anemia Obscured by the Obstructive Jaundice Associated with IgG4-related Sclerosing Cholangitis in a Patient with Type 1 Autoimmune Pancreatitis: A Case Report and Review of the Literature. ( 29269682 )
2017
19
Severe autoimmune hemolytic anemia during pegylated interferon plus ribavirin treatment for chronic hepatitis C: a case report. ( 28878911 )
2017
20
An unusual association between hemophagocytic lymphohistiocytosis, mixed connective tissue disease, and autoimmune hemolytic anemia: A case report. ( 28700492 )
2017
21
High prevalence of monoclonal gammopathy among patients with warm autoimmune hemolytic anemia. ( 28437873 )
2017
22
A case of pernicious anemia requiring differential diagnosis of autoimmune hemolytic anemia complication. ( 28948030 )
2017
23
Warm autoimmune hemolytic anemia: experience from a single referral center in Mexico City. ( 28401101 )
2017
24
Autoimmune Hemolytic Anemia in Plasmodium vivax Malaria. ( 28290054 )
2017
25
Autoimmune hemolytic anemia associated with trimethoprim-sulfamethoxazole use. ( 28596226 )
2017
26
A rare case of autoimmune hemolytic anemia. ( 28751361 )
2017
27
Rituximab in refractory autoimmune hemolytic anemia in systemic lupus erythematosus. ( 28870533 )
2017
28
Thyroid storm and warm autoimmune hemolytic anemia. ( 28870408 )
2017
29
C5aR activation in the absence of C5a: A new disease mechanism of autoimmune hemolytic anemia in mice. ( 29277896 )
2017
30
Prognostic impact of bone marrow fibrosis and dyserythropoiesis in autoimmune hemolytic anemia. ( 29274091 )
2017
31
Successful treatment of tacrolimus-related pure red cell aplasia and autoimmune hemolytic anemia with rituximab in a pediatric cardiac transplant patient. ( 28598573 )
2017
32
Fatal warm autoimmune hemolytic anemia in a child due to IgM-type autoantibodies. ( 27273179 )
2016
33
Clinical characteristics and treatment outcomes of primary autoimmune hemolytic anemia: a single center study from South India. ( 27382552 )
2016
34
Response to ibrutinib of refractory life-threatening autoimmune hemolytic anemia occurring in a relapsed chronic lymphocytic leukemia patient with 17p deletion. ( 26999572 )
2016
35
Life-Threatening Autoimmune Hemolytic Anemia and Idhiopatic Thrombocytopenic Purpura. Successful Selective Splenic Artery Embolization. ( 27158433 )
2016
36
Blood Group Discrepancy-First Sign of Autoimmune Hemolytic Anemia after Hematopoietic Stem Cell Transplantation in a Child. ( 27408394 )
2016
37
Coombs-negative Autoimmune Hemolytic Anemia Followed by Anti-erythropoetin Receptor Antibody-associated Pure Red Cell Aplasia: A Case Report and Review of Literature. ( 26935373 )
2016
38
Autoimmune hemolytic anemia in systemic lupus erythematosus at diagnosis: differences between pediatric and adult patients. ( 27821514 )
2016
39
No evidence of splenic disease in patients with splenic marginal zone lymphoma undergoing splenectomy for autoimmune hemolytic anemia after monotherapy with rituximab. ( 27082039 )
2016
40
Risk factor analysis of autoimmune hemolytic anemia after allogeneic hematopoietic stem cell transplantation in children. ( 27861376 )
2016
41
Expression of activated molecules on CD5(+)B lymphocytes in autoimmune hemolytic anemia. ( 26968550 )
2016
42
Autoimmune Hemolytic Anemia Induced by Adalimumab. ( 26984099 )
2016
43
Warm Autoimmune Hemolytic Anemia and Direct Antiglobulin Testing With a False-Negative Result in a 53-Year-Old Man: The DAT Will Set You Free. ( 27287943 )
2016
44
AOHE: manuscript AOHE-D-16-00564 paroxysmal nocturnal hemoglobinuria with autoimmune hemolytic anemia following eculizumab therapy-with large granular lymphocytic leukemia. ( 27449072 )
2016
45
Autoimmune hemolytic anemia after nivolumab treatment in Hodgkin lymphoma responsive to immunosuppressive treatment. A case report. ( 27539158 )
2016
46
Postoperative Recurrence of Invasive Thymoma with Cold Agglutinin Disease and Autoimmune Hemolytic Anemia. ( 27629968 )
2016
47
Difficult to swallow: warm autoimmune hemolytic anemia in a Jehovah's Witness treated with hemoglobin concentrate complicated by achalasia. ( 27062564 )
2016
48
Oral cyclophosphamide was effective for Coombs-negative autoimmune hemolytic anemia in CD16+CD56- chronic lymphoproliferative disorder of NK-cells. ( 28028749 )
2016
49
Blastic plasmacytoid dendritic cell neoplasm accompanied by autoimmune hemolytic anemia achieving complete remission with hydroxyurea and steroids. ( 26936199 )
2016
50
Autoimmune Hemolytic Anemia and Hodgkin's Disease: An Unusual Pediatric Association. ( 26904342 )
2016

Variations for Anemia, Autoimmune Hemolytic

Expression for Anemia, Autoimmune Hemolytic

Search GEO for disease gene expression data for Anemia, Autoimmune Hemolytic.

Pathways for Anemia, Autoimmune Hemolytic

GO Terms for Anemia, Autoimmune Hemolytic

Cellular components related to Anemia, Autoimmune Hemolytic according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.1 CD40LG CD5 CD55 CD79A RHCE RHD

Biological processes related to Anemia, Autoimmune Hemolytic according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 B cell proliferation GO:0042100 9.37 CD40LG CD79A
2 regulation of complement activation GO:0030449 9.33 C3 CD55 CD59
3 organic cation transport GO:0015695 9.32 RHCE RHD
4 ammonium transmembrane transport GO:0072488 9.26 RHCE RHD
5 neutrophil degranulation GO:0043312 9.02 C3 CD55 CD59 HP SIRPA
6 ammonium transport GO:0015696 8.96 RHCE RHD

Molecular functions related to Anemia, Autoimmune Hemolytic according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ammonium transmembrane transporter activity GO:0008519 8.62 RHCE RHD

Sources for Anemia, Autoimmune Hemolytic

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7 CNVD
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10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
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33 ICD10 via Orphanet
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36 KEGG
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41 MeSH
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58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
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68 Tocris
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70 UMLS via Orphanet
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