MCID: ANM001
MIFTS: 31

Anemia of Prematurity malady

Fetal diseases category

Summaries for Anemia of Prematurity

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63Wikipedia, 32MalaCards
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Wikipedia:63 Anemia of prematurity refers to a form of anemia affecting preterm infants with decreased hematocrit. more...

MalaCards: Anemia of Prematurity is related to deficiency anemia and neonatal anemia. An important gene associated with Anemia of Prematurity is EPO (erythropoietin), and among its related pathways are Jak-STAT signaling pathway and Hematopoietic cell lineage. The compounds pegfilgrastim and anagrelide have been mentioned in the context of this disorder. Affiliated tissues include heart.

Aliases & Classifications for Anemia of Prematurity

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Sources:
8Disease Ontology, 60UMLS, 27ICD9CM, 56SNOMED-CT, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Fetal diseases


Aliases & Descriptions:

anemia of prematurity 8


External Ids:

Disease Ontology8 DOID:11243
ICD9CM27 776.6
SNOMED-CT56 47100003
ICD1025 P61.2

Related Diseases for Anemia of Prematurity

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17GeneCards, 18GeneDecks
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Graphical network of diseases related to Anemia of Prematurity:



Diseases related to anemia of prematurity

Clinical Features for Anemia of Prematurity

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Drugs & Therapeutics for Anemia of Prematurity

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Anemia of Prematurity

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Anatomical Context for Anemia of Prematurity

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32MalaCards
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MalaCards organs/tissues related to Anemia of Prematurity:

32
Heart

Animal Models for Anemia of Prematurity or affiliated genes

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Publications for Anemia of Prematurity

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50PubMed
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Articles related to Anemia of Prematurity:

(show top 50)    (show all 102)
idTitleAuthorsYear
1
Exploring the use of expanded erythroid cells for autologous transfusion for anemia of prematurity. (23521158)
2013
2
Effect of short-term recombinant human erythropoietin therapy in the prevention of anemia of prematurity in very low birth weight neonates. (23540189)
2012
3
Necrotizing enterocolitis and the role of anemia of prematurity. (22818548)
2012
4
Wilms tumor, AML, and medulloblastoma in a child with cancer prone syndrome of total premature chromatid separation and Fanconi anemia. (19856400)
2010
5
Is there a role for autologous/placental red blood cell transfusions in the anemia of prematurity? (20303035)
2010
6
Current controversies in the management of the anemia of prematurity. (19167579)
2009
7
Wilms tumor, AML and medulloblastoma in a child with cancer prone syndrome of total premature chromatid separation and Fanconi anemia. (19373780)
2009
8
Erythrocyte transfusions and serum prohepcidin levels in premature newborns with anemia of prematurity. (19816209)
2009
9
Pathophysiology of Anemia During the Neonatal Period, Including Anemia of Prematurity. (20463861)
2008
10
A clinical study on the feasibility of autologous cord blood transfusion for anemia of prematurity. (18507748)
2008
11
Controversies in the management of the anemia of prematurity using single-donor red blood cell transfusions and/or recombinant human erythropoietin. (16373186)
2006
12
Does early erythropoietin therapy decrease transfusions in anemia of prematurity? (12061670)
2002
13
The role of high-dose oral iron supplementation during erythropoietin therapy for anemia of prematurity. (11533837)
2001
14
The effect of recombinant human erythropoietin on the treatment of anemia of prematurity (14647595)
2001
15
Prophylaxis of anemia of prematurity with erythropoietin. Case control study]. (11083968)
2000
16
Erythropoietin to prevent and treat the anemia of prematurity. (10202619)
1999
17
The use of erythropoietin in treatment of anemia of prematurity. (9601351)
1998
18
Myocardial, erythropoietic, and metabolic adaptations to anemia of prematurity in infants with bronchopulmonary dysplasia. (9580761)
1998
19
Erythropoietin to treat anemia of prematurity. (9161667)
1997
20
Recombinant erythropoietin for the anemia of prematurity: still a promise, not a panacea. (9403639)
1997
21
Randomized multi-center trial of the administration of erythropoietin in anemia of prematurity]. (9297428)
1997
22
Do cardiac output and serum lactate levels indicate blood transfusion requirements in anemia of prematurity? (8796405)
1996
23
Erythropoietin--not yet a standard treatment for anemia of prematurity. (7770317)
1995
24
Pathophysiology and treatment of the anemia of prematurity. (7743231)
1995
25
Use of epoetin (erythropoietin) in the anemia of prematurity. (7747503)
1995
26
Effects of recombinant human erythropoietin in the treatment of anemia of prematurity]. (7739926)
1995
27
Recombinant human erythropoietin in the treatment of anemia of prematurity. (8540930)
1995
28
Blood transfusion in late anemia of prematurity: effect on oxygen consumption, heart rate, and weight gain in otherwise healthy infants. (7873916)
1994
29
Erythropoietin production by macrophages from preterm infants: implications regarding the cause of the anemia of prematurity. (8165050)
1994
30
Recombinant human erythropoietin vs transfusions in the treatment of anemia of prematurity. A cost-benefit analysis. (8193681)
1994
31
Lactic acid as a predictor for erythrocyte transfusion in healthy preterm infants with anemia of prematurity. (8463915)
1993
32
Anemia of prematurity: the prospects for avoiding blood transfusions by treatment with recombinant human erythropoietin. (8249712)
1993
33
In which neonates does early recombinant human erythropoietin treatment prevent anemia of prematurity? Results of a randomized, controlled study. (8284109)
1993
34
Erythropoietin therapy for anemia of prematurity. (1552415)
1992
35
Use of recombinant erythropoietin in treatment of the anemia of prematurity. (1793163)
1991
36
Anemia of prematurity: progress and prospects. (2178457)
1990
37
Rationale for using recombinant human erythropoietin to treat the anemia of prematurity. (2684531)
1989
38
Circulating erythroid progenitors in the anemia of prematurity. (3627181)
1987
39
Lessons from the anemia of prematurity. (3329178)
1987
40
Anemia of prematurity. Current concepts in the issue of when to transfuse. (3513096)
1986
41
Erythropoietin and the anemia of prematurity. (4056994)
1985
42
Erythropoietin and the anemia of prematurity. (6502305)
1984
43
Decreased response of plasma immunoreactive erythropoietin to "available oxygen" in anemia of prematurity. (6502313)
1984
44
The anemia of prematurity and the decision when to transfuse. (6369939)
1983
45
Plasma vitamin E levels and vitamin E/beta-lipoprotein relationships in small preterm infants during the early anemia of prematurity. (7227390)
1981
46
Physiological anemia of infancy and anemia of prematurity. (7024124)
1981
47
Anemia of prematurity. (332429)
1977
48
The use of intramuscular iron in the prophylaxis of the iron-deficiency anemia of prematurity. (14415450)
1960
49
Erythrocyte production and iron stores in premature infants during the first months of life; the anemia of prematurity-etiology, pathogenesis, iron requirement. (13381463)
1956
50
Studies on the anemia of prematurity. (13206378)
1954

Genetic Variations for Anemia of Prematurity

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Expression for genes affiliated with Anemia of Prematurity

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Anemia of Prematurity

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Pathways for genes affiliated with Anemia of Prematurity

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29KEGG
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Pathways related to Anemia of Prematurity according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3EPO, CSF2
29.3EPO, CSF2

Compounds for genes affiliated with Anemia of Prematurity

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Sources:
44Novoseek, 11DrugBank, 28IUPHAR, 49PharmGKB, 59Tocris Bioscience, 2BitterDB, 24HMDB
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Compounds related to Anemia of Prematurity according to GeneCards/GeneDecks:

(show all 26)
idCompoundScoreTop Affiliating Genes
1pegfilgrastim44 1110.7EPO, CSF2
2anagrelide44 1110.7EPO, CSF2
3pixy321449.7EPO, CSF2
4amifostine44 1110.7EPO, CSF2
5filgrastim44 1110.7EPO, CSF2
6gm-csf44 2810.7EPO, CSF2
7methylcellulose449.6EPO, CSF2
8ribavirin44 49 1111.6EPO, CSF2
9melphalan44 1110.6CSF2, EPO
10carboplatin44 49 1111.6EPO, CSF2
11bleomycin44 1110.6EPO, CSF2
12thalidomide44 49 59 1112.6CSF2, EPO
13zidovudine44 1110.6EPO, CSF2
14hydroxyurea44 49 1111.5EPO, CSF2
15gp 130449.4EPO, CSF2
16bryostatin 1449.4CSF2, AREG
17cytarabine44 49 1111.3CSF2, EPO
18hydrocortisone44 2 59 1112.2EPO, CSF2
19mitomycin c449.2EPO, AREG
20inositol449.0EPO, CSF2
21isoproterenol44 1110.0AREG, CSF2
22calcitriol44 59 11 2411.9CSF2, AREG, EPO
23cisplatin44 49 59 1111.8EPO, AREG, CSF2
24thymidine44 249.8CSF2, AREG, EPO
25vegf448.7EPO, AREG, CSF2
26phosphatidylinositol448.7CSF2, AREG, EPO

GO Terms for genes affiliated with Anemia of Prematurity

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16Gene Ontology
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Biological processes related to Anemia of Prematurity according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of DNA replicationGO:0457409.3EPO, CSF2
2positive regulation of tyrosine phosphorylation of Stat5 proteinGO:0425239.0EPO, CSF2

Products for genes affiliated with Anemia of Prematurity

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Anemia of Prematurity

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet