MCID: ANM001
MIFTS: 37

Anemia of Prematurity malady

Fetal diseases, Blood diseases categories
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Summaries for Anemia of Prematurity

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Wikipedia:65 Anemia of prematurity refers to a form of anemia affecting preterm infants with decreased hematocrit. more...

MalaCards based summary: Anemia of Prematurity, also known as anaemia of prematurity, is related to deficiency anemia and 5q- syndrome. An important gene associated with Anemia of Prematurity is EPO (erythropoietin), and among its related pathways are Jak-STAT signaling pathway and Hematopoietic cell lineage. The compounds mitomycin c and bryostatin 1 have been mentioned in the context of this disorder. Affiliated tissues include heart, and related mouse phenotypes are cardiovascular system and integument.

Aliases & Classifications for Anemia of Prematurity

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Anemia of Prematurity, Aliases & Descriptions:

Name: Anemia of Prematurity 8
 
Anaemia of Prematurity 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Fetal diseases
Anatomical: Blood diseases


External Ids:

Disease Ontology8 DOID:11243
ICD9CM27 776.6
SNOMED-CT57 47100003
ICD1025 P61.2

Related Diseases for Anemia of Prematurity

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Graphical network of the top 20 diseases related to Anemia of Prematurity:



Diseases related to anemia of prematurity

Symptoms for Anemia of Prematurity

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Drugs & Therapeutics for Anemia of Prematurity

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Drug clinical trials:

Search ClinicalTrials for Anemia of Prematurity

Search NIH Clinical Center for Anemia of Prematurity

Genetic Tests for Anemia of Prematurity

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Anatomical Context for Anemia of Prematurity

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MalaCards organs/tissues related to Anemia of Prematurity:

32
Heart

Animal Models for Anemia of Prematurity or affiliated genes

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MGI Mouse Phenotypes related to Anemia of Prematurity:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053858.5AREG, CSF2, EPO
2MP:00107718.2AREG, CSF2, EPO

Publications for Anemia of Prematurity

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Articles related to Anemia of Prematurity:

(show top 50)    (show all 96)
idTitleAuthorsYear
1
Exploring the use of expanded erythroid cells for autologous transfusion for anemia of prematurity. (23521158)
2013
2
Erythropoietin in anemia of prematurity. (23025776)
2012
3
Effect of short-term recombinant human erythropoietin therapy in the prevention of anemia of prematurity in very low birth weight neonates. (23540189)
2012
4
Is there a role for autologous/placental red blood cell transfusions in the anemia of prematurity? (20303035)
2010
5
Current controversies in the management of the anemia of prematurity. (19167579)
2009
6
Pathophysiology of Anemia During the Neonatal Period, Including Anemia of Prematurity. (20463861)
2008
7
A randomized, controlled trial of the effects of adding vitamin B12 and folate to erythropoietin for the treatment of anemia of prematurity. (16818564)
2006
8
Effects of transfusion in anemia of prematurity. (16166047)
2005
9
Erythropoietin in anemia of prematurity. (12785302)
2003
10
Human recombinant erythropoietin in the prevention and treatment of anemia of prematurity. (11888358)
2002
11
Does early erythropoietin therapy decrease transfusions in anemia of prematurity? (12061670)
2002
12
The role of high-dose oral iron supplementation during erythropoietin therapy for anemia of prematurity. (11533837)
2001
13
Anemia of prematurity. (12144218)
2001
14
Managing the anemia of prematurity: red blood cell transfusions versus recombinant erythropoietin. (11471123)
2001
15
Meta-analysis of controlled clinical trials studying the efficacy of rHuEPO in reducing blood transfusions in the anemia of prematurity. (11274599)
2001
16
Recombinant human erythropoietin in anemia of prematurity. (10709119)
1999
17
The use of erythropoietin in treatment of anemia of prematurity. (9601351)
1998
18
Recombinant human erythropoietin therapy for treatment of anemia of prematurity in very low birth weight infants: a randomized, double-blind, placebo-controlled trial. (9659643)
1998
19
Erythropoietin to treat anemia of prematurity. (9161667)
1997
20
Recombinant erythropoietin for the anemia of prematurity: still a promise, not a panacea. (9403639)
1997
21
The role of erythropoietin in the anemia of prematurity. (9190030)
1997
22
Erythropoietin therapy for anemia of prematurity. (8772909)
1996
23
Erythropoietin--not yet a standard treatment for anemia of prematurity. (7770317)
1995
24
A cost analysis comparing erythropoietin and red cell transfusions in the treatment of anemia of prematurity. (8604492)
1995
25
Pathophysiology and treatment of the anemia of prematurity. (7743231)
1995
26
Evaluation of treatment results for anemia of prematurity treated with various doses of human recombinant erythropoietin]. (8657506)
1995
27
Use of epoetin (erythropoietin) in the anemia of prematurity. (7747503)
1995
28
The effect of recombinant human erythropoietin in treating the anemia of prematurity. (7793277)
1995
29
Follow-up of very low birth weight infants after erythropoietin treatment to prevent anemia of prematurity. (7636658)
1995
30
Blood transfusion in late anemia of prematurity: effect on oxygen consumption, heart rate, and weight gain in otherwise healthy infants. (7873916)
1994
31
Recombinant erythropoietin in anemia of prematurity: five years later. (8414840)
1993
32
Erythropoietin therapy for anemia of prematurity. (1552415)
1992
33
Recombinant erythropoietin compared with erythrocyte transfusion in the treatment of anemia of prematurity. (1941387)
1991
34
Use of recombinant erythropoietin in treatment of the anemia of prematurity. (1793163)
1991
35
Erythroid "burst promoting" activity in serum of patients with the anemia of prematurity. (2184214)
1990
36
Prediction of the need for transfusion during anemia of prematurity. (2184213)
1990
37
Circulating erythroid progenitors in the anemia of prematurity. (3627181)
1987
38
Anemia of prematurity. Current concepts in the issue of when to transfuse. (3513096)
1986
39
Erythropoietin and the anemia of prematurity. (4056994)
1985
40
Erythropoietin and the anemia of prematurity. (6502305)
1984
41
Anemia of prematurity: determinants of the erythropoietin response. (6502312)
1984
42
Plasma erythropoietin concentrations during the early anemia of prematurity. (6673483)
1983
43
The anemia of prematurity and the decision when to transfuse. (6369939)
1983
44
Anemia of prematurity. (7013658)
1981
45
The anemia of prematurity. Factors governing the erythropoietin response. (851485)
1977
46
Anemia of prematurity. (1167980)
1975
47
The use of intramuscular iron in the prophylaxis of the iron-deficiency anemia of prematurity. (14415450)
1960
48
The anemia of prematurity. (13642236)
1959
49
Use of cobalt and iron in the treatment and prevention of anemia of prematurity. (14368067)
1955
50
Studies on the anemia of prematurity. (13206378)
1954

Variations for Anemia of Prematurity

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Expression for genes affiliated with Anemia of Prematurity

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Expression patterns in normal tissues for genes affiliated with Anemia of Prematurity

Search GEO for disease gene expression data for Anemia of Prematurity.

Pathways for genes affiliated with Anemia of Prematurity

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Pathways related to Anemia of Prematurity according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Type III interferon signaling37
9.0CSF2, EPO
29.0CSF2, EPO

Compounds for genes affiliated with Anemia of Prematurity

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Compounds related to Anemia of Prematurity according to GeneCards/GeneDecks:

(show all 42)
idCompoundScoreTop Affiliating Genes
1mitomycin c449.7AREG, EPO
2bryostatin 1449.5AREG, CSF2
3pegfilgrastim44 1110.5CSF2, EPO
4anagrelide44 1110.5EPO, CSF2
5pixy321449.5CSF2, EPO
6amifostine44 1110.5CSF2, EPO
7filgrastim44 1110.4EPO, CSF2
8isoproterenol44 1110.4AREG, CSF2
9gm-csf44 2810.4CSF2, EPO
10methylcellulose449.4EPO, CSF2
11ribavirin44 50 1111.4CSF2, EPO
12melphalan44 50 1111.4CSF2, EPO
1312-o-tetradecanoylphorbol 13-acetate449.4AREG, CSF2
14bleomycin44 1110.4EPO, CSF2
15thalidomide44 50 61 1112.4CSF2, EPO
16sb 20358044 6110.4CSF2, AREG
17zidovudine44 50 1111.4CSF2, EPO
18carboplatin44 50 1111.4EPO, CSF2
19hydroxyurea44 50 1111.4CSF2, EPO
20gp 130449.4EPO, CSF2
21polysaccharide449.4CSF2, AREG
22cytarabine44 50 1111.4CSF2, EPO
23hydrocortisone44 2 61 1112.4EPO, CSF2
24inositol449.4CSF2, EPO
25norepinephrine44 24 1111.3AREG, CSF2
26gnrh449.3CSF2, EPO
27pd 98,059449.3CSF2, AREG
28butyrate449.3CSF2, EPO
29wortmannin449.3AREG, CSF2
30vitamin d449.3CSF2, EPO
31actinomycin d449.2CSF2, AREG
32pge2449.1AREG, CSF2
33cycloheximide449.1AREG, CSF2
34cyclosporin a44 28 6111.1CSF2, EPO
35calcitriol44 61 24 1111.9AREG, CSF2, EPO
36lactate448.9EPO, CSF2
37thymidine44 249.9AREG, CSF2, EPO
38cisplatin44 50 61 1111.9EPO, CSF2, AREG
39vegf448.9AREG, CSF2, EPO
40phosphatidylinositol448.9EPO, CSF2, AREG
41heparin44 28 24 1111.8AREG, CSF2
42tyrosine448.8EPO, CSF2, AREG

GO Terms for genes affiliated with Anemia of Prematurity

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Biological processes related to Anemia of Prematurity according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of cell proliferationGO:0082849.0CSF2, EPO
2positive regulation of tyrosine phosphorylation of Stat5 proteinGO:0425238.9CSF2, EPO
3positive regulation of DNA replicationGO:0457408.7CSF2, EPO

Products for genes affiliated with Anemia of Prematurity

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Sources for Anemia of Prematurity

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet