MCID: ANM001
MIFTS: 31

Anemia of Prematurity malady

Fetal diseases category

Summaries for Anemia of Prematurity

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63Wikipedia, 32MalaCards
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Wikipedia:63 Anemia of prematurity refers to a form of anemia affecting preterm infants with decreased hematocrit. more...

MalaCards: Anemia of Prematurity is related to deficiency anemia and neonatal anemia. An important gene associated with Anemia of Prematurity is EPO (erythropoietin), and among its related pathways are Jak-STAT signaling pathway and Hematopoietic cell lineage. The compounds pegfilgrastim and anagrelide have been mentioned in the context of this disorder. Affiliated tissues include heart.

Aliases & Classifications for Anemia of Prematurity

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8Disease Ontology, 60UMLS, 27ICD9CM, 56SNOMED-CT, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Fetal diseases


Aliases & Descriptions:

anemia of prematurity 8


External Ids:

Disease Ontology8 DOID:11243
ICD9CM27 776.6
SNOMED-CT56 47100003
ICD1025 P61.2

Related Diseases for Anemia of Prematurity

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17GeneCards, 18GeneDecks
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Graphical network of diseases related to Anemia of Prematurity:



Diseases related to anemia of prematurity

Clinical Features for Anemia of Prematurity

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Drugs & Therapeutics for Anemia of Prematurity

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Anemia of Prematurity

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Anatomical Context for Anemia of Prematurity

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32MalaCards
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MalaCards organs/tissues related to Anemia of Prematurity:

32
Heart

Animal Models for Anemia of Prematurity or affiliated genes

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Publications for Anemia of Prematurity

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50PubMed
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Articles related to Anemia of Prematurity:

(show top 50)    (show all 102)
idTitleAuthorsYear
1
Erythropoietin in anemia of prematurity. (23025776)
2012
2
Comparison of oral recombinant erythropoietin and subcutaneous recombinant erythropoietin in prevention of anemia of prematurity. (22737576)
2012
3
Wilms tumor, AML and medulloblastoma in a child with cancer prone syndrome of total premature chromatid separation and Fanconi anemia. (19373780)
2009
4
A randomized, controlled trial of the effects of adding vitamin B12 and folate to erythropoietin for the treatment of anemia of prematurity. (16818564)
2006
5
Erythropoietin in anemia of prematurity. (12785302)
2003
6
Human recombinant erythropoietin in the prevention and treatment of anemia of prematurity. (11888358)
2002
7
Iron status and the treatment of the anemia of prematurity. (12168242)
2002
8
Anemia of prematurity. (12144218)
2001
9
Managing the anemia of prematurity: red blood cell transfusions versus recombinant erythropoietin. (11471123)
2001
10
Meta-analysis of controlled clinical trials studying the efficacy of rHuEPO in reducing blood transfusions in the anemia of prematurity. (11274599)
2001
11
Recombinant human erythropoietin in anemia of prematurity. (10709119)
1999
12
Comparison between two and five doses a week of recombinant human erythropoietin for anemia of prematurity: a randomized trial. (10428996)
1999
13
Financial impact of the introduction of erythropoietin in the treatment of anemia of premature infants in Israel. (10731302)
1999
14
Recombinant human erythropoietin therapy for treatment of anemia of prematurity in very low birth weight infants: a randomized, double-blind, placebo-controlled trial. (9659643)
1998
15
Erythropoietin to treat anemia of prematurity. (9161667)
1997
16
The role of erythropoietin in the anemia of prematurity. (9190030)
1997
17
Erythropoietin therapy for anemia of prematurity. (8772909)
1996
18
Effect of protein intake on erythropoiesis during erythropoietin treatment of anemia of prematurity. (8618185)
1996
19
Pathophysiology and treatment of the anemia of prematurity. (7743231)
1995
20
The effect of recombinant human erythropoietin in treating the anemia of prematurity. (7793277)
1995
21
Follow-up of very low birth weight infants after erythropoietin treatment to prevent anemia of prematurity. (7636658)
1995
22
Recombinant human erythropoietin in the treatment of anemia of prematurity. (8540930)
1995
23
Potential for treatment of anemia of prematurity with recombinant human erythropoietin. (7787927)
1995
24
Blood transfusion in late anemia of prematurity: effect on oxygen consumption, heart rate, and weight gain in otherwise healthy infants. (7873916)
1994
25
Pilot study comparing recombinant erythropoietin alone with erythropoietin plus recombinant granulocyte-macrophage colony-stimulating factor for treatment of the anemia of prematurity. (8014692)
1994
26
The reactivation of fetal hemoglobin synthesis during anemia of prematurity. (7526326)
1994
27
Myocardial, erythropoietic, and metabolic adaptations to anemia of prematurity. (8040778)
1994
28
Recombinant erythropoietin in anemia of prematurity: five years later. (8414840)
1993
29
Erythropoietin therapy for anemia of prematurity. (8458164)
1993
30
Recombinant erythropoietin compared with erythrocyte transfusion in the treatment of anemia of prematurity. (1941387)
1991
31
Physiologic sequelae of prematurity: the nurse practitioner's role. Part IV. Anemia. (1990113)
1991
32
Recombinant human erythropoietin in the anemia of prematurity: results of a placebo-controlled pilot study. (2040933)
1991
33
A randomized, placebo-controlled clinical trial of recombinant human erythropoietin in the anemia of prematurity. (2040193)
1991
34
The changing pattern of maternal and neonatal anemia at Udaipur during 2 decades in relation to poverty, parity, prematurity and vegetarianism. (2064586)
1991
35
Prediction of the need for transfusion during anemia of prematurity. (2184213)
1990
36
Rationale for using recombinant human erythropoietin to treat the anemia of prematurity. (2684531)
1989
37
Circulating erythroid progenitors in the anemia of prematurity. (3627181)
1987
38
Anemia of prematurity. Current concepts in the issue of when to transfuse. (3513096)
1986
39
Plasma erythropoietin concentrations during the early anemia of prematurity. (6673483)
1983
40
Anemia of prematurity. (7013658)
1981
41
Ceruloplasmin levels and erythrocyte superoxide dismutase activity in small preterm infants during the early anemia of prematurity. (7324938)
1981
42
The anemia of prematurity. Factors governing the erythropoietin response. (851485)
1977
43
Anemia of prematurity. (332429)
1977
44
Anemia of prematurity. (1167980)
1975
45
Premature chromosome condensation in a case of Fanconi's anemia. (1150270)
1975
46
The anemia of prematurity. (13642236)
1959
47
Use of cobalt and iron in the treatment and prevention of anemia of prematurity. (14368067)
1955
48
Effect of a cobalt-iron mixture on the anemia of prematurity. (13169050)
1954
49
Further comments on cobalt-iron therapy of anemia of prematurity. (13205508)
1954
50
Fetal and adult hemoglobins in premature infants with observations on the mechanism of the anemia of prematurity. (13091330)
1953

Genetic Variations for Anemia of Prematurity

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Expression for genes affiliated with Anemia of Prematurity

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Anemia of Prematurity

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Pathways for genes affiliated with Anemia of Prematurity

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29KEGG
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Pathways related to Anemia of Prematurity according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3EPO, CSF2
29.3EPO, CSF2

Compounds for genes affiliated with Anemia of Prematurity

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44Novoseek, 11DrugBank, 28IUPHAR, 49PharmGKB, 59Tocris Bioscience, 2BitterDB, 24HMDB
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Compounds related to Anemia of Prematurity according to GeneCards/GeneDecks:

(show all 26)
idCompoundScoreTop Affiliating Genes
1pegfilgrastim44 1110.7EPO, CSF2
2anagrelide44 1110.7EPO, CSF2
3pixy321449.7EPO, CSF2
4amifostine44 1110.7EPO, CSF2
5filgrastim44 1110.7EPO, CSF2
6gm-csf44 2810.7EPO, CSF2
7methylcellulose449.6EPO, CSF2
8ribavirin44 49 1111.6EPO, CSF2
9melphalan44 1110.6CSF2, EPO
10carboplatin44 49 1111.6EPO, CSF2
11bleomycin44 1110.6EPO, CSF2
12thalidomide44 49 59 1112.6CSF2, EPO
13zidovudine44 1110.6EPO, CSF2
14hydroxyurea44 49 1111.5EPO, CSF2
15gp 130449.4EPO, CSF2
16bryostatin 1449.4CSF2, AREG
17cytarabine44 49 1111.3CSF2, EPO
18hydrocortisone44 2 59 1112.2EPO, CSF2
19mitomycin c449.2EPO, AREG
20inositol449.0EPO, CSF2
21isoproterenol44 1110.0AREG, CSF2
22calcitriol44 59 11 2411.9CSF2, AREG, EPO
23cisplatin44 49 59 1111.8EPO, AREG, CSF2
24thymidine44 249.8CSF2, AREG, EPO
25vegf448.7EPO, AREG, CSF2
26phosphatidylinositol448.7CSF2, AREG, EPO

GO Terms for genes affiliated with Anemia of Prematurity

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16Gene Ontology
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Biological processes related to Anemia of Prematurity according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of DNA replicationGO:0457409.3EPO, CSF2
2positive regulation of tyrosine phosphorylation of Stat5 proteinGO:0425239.0EPO, CSF2

Products for genes affiliated with Anemia of Prematurity

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Anemia of Prematurity

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet