MCID: ANM001
MIFTS: 41

Anemia of Prematurity malady

Categories: Fetal diseases, Blood diseases

Aliases & Classifications for Anemia of Prematurity

Aliases & Descriptions for Anemia of Prematurity:

Name: Anemia of Prematurity 12 14

Classifications:



External Ids:

Disease Ontology 12 DOID:11243
ICD10 33 P61.2
ICD9CM 35 776.6
NCIt 47 C97167
SNOMED-CT 64 47100003
UMLS 69 C0158996

Summaries for Anemia of Prematurity

MalaCards based summary : Anemia of Prematurity is related to choledochal cyst and myotonic dystrophy 1. An important gene associated with Anemia of Prematurity is EPO (Erythropoietin), and among its related pathways/superpathways are PEDF Induced Signaling and Akt Signaling. The drugs Iron and Copper have been mentioned in the context of this disorder. Affiliated tissues include heart, and related phenotypes are homeostasis/metabolism and hematopoietic system

Wikipedia : 71 Anemia of prematurity refers to a form of anemia affecting preterm infants with decreased... more...

Related Diseases for Anemia of Prematurity

Diseases related to Anemia of Prematurity via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 39)
id Related Disease Score Top Affiliating Genes
1 choledochal cyst 10.2 CSF2 IL3
2 myotonic dystrophy 1 10.2 EPO KITLG
3 queensland tick typhus 10.2 EPO EPOR IL3
4 atrioventricular septal defect 2 10.2 EPO EPOR
5 pyloric stenosis, infantile hypertrophic, 4 10.2 EPO IL3
6 long qt syndrome 10.2 EPO EPOR
7 cytokine receptor deficiency 10.1 CSF2 IL3 KITLG
8 granulomatous hepatitis 10.1 CSF2 EPO IL3
9 middle cerebral artery infarction 10.1 CSF2 IL3 KITLG
10 eosinophilic cystitis 10.0 CSF2 CSF3
11 febrile seizures, familial, 2 10.0 CSF2 CSF3 IL3
12 mental retardation, autosomal dominant 37 10.0 CSF2 CSF3 IL3
13 scleroderma, familial progressive 10.0 CSF2 CSF3 IL3
14 blood coagulation disease 10.0 CSF2 CSF3 EPO
15 grix blankenship peterson syndrome 9.9 CSF2 CSF3 IL3
16 medullary cystic kidney disease 1 9.9 CSF2 STAT5A STAT5B
17 intestinal impaction 9.9 EPO EPOR IL3 KITLG STAT5A
18 erythrocytosis, somatic 9.9 EPO EPOR IL3 KITLG STAT5A
19 extranodal nasal nk/t cell lymphoma 9.9 CSF3 EPO EPOR KITLG
20 drug-induced hepatitis 9.9 CSF2 EPO EPOR GYPA IL3 KITLG
21 autoimmune disease of eyes, ear, nose and throat 9.9 STAT5A STAT5B
22 cerebellar hypoplasia and mental retardation with or without quadrupedal locomotion 1 9.8 EPO EPOR IL3 STAT5A STAT5B
23 sinusitis 9.8 CSF2 CSF3 IL3 KITLG
24 acute dacryoadenitis 9.8 CSF2 CSF3 IL3 KITLG
25 membranoproliferative glomerulonephritis 9.8 CSF2 CSF3 EPO HAMP
26 osteoarthritis 9.8 CSF2 CSF3 IL3 KITLG
27 neuronal ceroid-lipofuscinoses 9.7 CSF3 EPO EPOR HAMP IL3
28 hyperparathyroidism, neonatal 9.7 CSF2 CSF3 EPO IL3 KITLG
29 hemophagocytic lymphohistiocytosis 9.7 CSF2 CSF3 IL3 KITLG STAT5B
30 immunodeficiency due to defect in mapbp-interacting protein 9.6 CSF2 CSF3 EPO GYPA HAMP SLC4A1
31 deficiency anemia 9.5
32 bronchopulmonary dysplasia 9.5
33 iron deficiency anemia 9.5
34 basilar artery insufficiency 9.5 CSF3 EPO EPOR IL3 STAT5A STAT5B
35 leukemia, acute myeloid 9.5 CSF2 CSF3 EPO EPOR IL3 KITLG
36 peroxisome biogenesis disorder 7a 9.4 CSF2 CSF3 EPO IL3 KITLG STAT5A
37 cranioectodermal dysplasia 1 9.3 CSF2 CSF3 GYPA IL3 KITLG STAT5A
38 actinobacillosis 9.3 CSF2 CSF3 EPO EPOR IL3 KITLG
39 dic in newborn 8.0 CSF2 CSF3 EPO EPOR GPX3 GYPA

Graphical network of the top 20 diseases related to Anemia of Prematurity:



Diseases related to Anemia of Prematurity

Symptoms & Phenotypes for Anemia of Prematurity

MGI Mouse Phenotypes related to Anemia of Prematurity:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.13 CSF2 EPO EPOR GPX3 HIF1AN KITLG
2 hematopoietic system MP:0005397 10.11 CSF2 CSF3 EPO EPOR GPX3 KITLG
3 cellular MP:0005384 10.1 CSF2 EPO EPOR HIF1AN KITLG SCO2
4 cardiovascular system MP:0005385 10.09 CSF2 EPO EPOR GPX3 HIF1AN KITLG
5 immune system MP:0005387 9.96 PTGDR SLC4A1 SLC7A11 STAT5A STAT5B CSF2
6 integument MP:0010771 9.81 CSF2 CSF3 EPO KITLG PTGDR SLC4A1
7 liver/biliary system MP:0005370 9.56 SCO2 STAB2 STAT5A STAT5B EPO EPOR
8 mortality/aging MP:0010768 9.36 KITLG PTGDR SCO2 SLC4A1 STAB2 STAT5A

Drugs & Therapeutics for Anemia of Prematurity

Drugs for Anemia of Prematurity (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 165)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Iron Approved Phase 4,Phase 3,Phase 2 7439-89-6 23925
2
Copper Approved Phase 4,Phase 3,Phase 2 15158-11-9, 7440-50-8 27099
3
Hydroxocobalamin Approved Phase 4,Phase 3,Phase 2 13422-51-0 11953898 5460373 44475014
4
Selenium Approved, Vet_approved Phase 4,Phase 3 7782-49-2
5
Zinc Approved Phase 4,Phase 3 7440-66-6 32051 23994
6
Pyrimethamine Approved, Vet_approved Phase 4,Phase 3 58-14-0 4993
7
Sulfadoxine Approved Phase 4,Phase 3 2447-57-6 17134
8
Cyclosporine Approved, Investigational, Vet_approved Phase 4 79217-60-0, 59865-13-3 5284373 6435893
9
Everolimus Approved Phase 4 159351-69-6 6442177
10
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3 22916-47-8 4189
11
Sirolimus Approved, Investigational Phase 4 53123-88-9 5284616 6436030 46835353
12
chloroquine Approved, Vet_approved Phase 4,Phase 3 54-05-7 2719
13
Cyanocobalamin Approved, Nutraceutical Phase 4,Phase 3,Phase 2 68-19-9 44176380
14
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 59-30-3 6037
15
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2 58-05-9 54575, 6560146 143
16
Niacin Approved, Investigational, Nutraceutical Phase 4,Phase 3,Phase 2 59-67-6 938
17
Nicotinamide Approved, Nutraceutical Phase 4,Phase 3,Phase 2 98-92-0 936
18
Pyridoxal Approved, Nutraceutical Phase 4,Phase 3,Phase 2 66-72-8 1050
19
Pyridoxine Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 65-23-6 1054
20
Riboflavin Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 83-88-5 493570
21
Thiamine Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 59-43-8 1130
22
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 11103-57-4, 68-26-8 445354
23
Vitamin C Approved, Nutraceutical Phase 4,Phase 3,Phase 2 50-81-7 5785 54670067
24
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4,Phase 3 59-02-9 14985
25 Ferric oxide, saccharated Phase 4
26 Hematinics Phase 4,Phase 2,Phase 3,Phase 1
27 Micronutrients Phase 4,Phase 3,Phase 2
28 Trace Elements Phase 4,Phase 3,Phase 2
29 Epoetin alfa Phase 4,Phase 2,Phase 3,Phase 1 113427-24-0
30 Pharmaceutical Solutions Phase 4,Phase 2,Phase 3,Phase 1
31 cadexomer iodine Phase 4,Phase 3,Phase 2
32
Iodine Phase 4,Phase 3,Phase 2 7553-56-2 807
33 Nicotinic Acids Phase 4,Phase 3,Phase 2
34 Retinol palmitate Phase 4,Phase 3,Phase 2
35 Tocopherols Phase 4,Phase 3
36 Tocotrienols Phase 4,Phase 3
37 Vitamin B 12 Phase 4,Phase 3,Phase 2
38 Vitamin B 6 Phase 4,Phase 3,Phase 2
39 Vitamin B Complex Phase 4,Phase 3,Phase 2
40 vitamin d Phase 4,Phase 3,Phase 2
41 Vitamins Phase 4,Phase 3,Phase 2
42 Anti-Infective Agents Phase 4,Phase 3,Phase 2
43 Antimalarials Phase 4,Phase 3
44 Antiparasitic Agents Phase 4,Phase 3
45 Antiprotozoal Agents Phase 4,Phase 3
46 Fanasil, pyrimethamine drug combination Phase 4,Phase 3
47 Folic Acid Antagonists Phase 4,Phase 3
48 Renal Agents Phase 4,Phase 3
49 Anti-Bacterial Agents Phase 4,Phase 3
50 Antibiotics, Antitubercular Phase 4

Interventional clinical trials:

(show top 50) (show all 101)
id Name Status NCT ID Phase
1 Effects of Early Short-term Intravenous Iron Supplements Combinded EPO in Preterm Infants Unknown status NCT02060851 Phase 4
2 Effect of Erythropoietin on Preterm Brain Injury Completed NCT02036073 Phase 4
3 Prevention of Intrauterine Growth Retardation in Hounde District, Burkina Faso Completed NCT00642408 Phase 4
4 Intermittent Preventive Treatment of Malaria in HIV-Seropositive Pregnant Women in Zambia Completed NCT00270530 Phase 4
5 Open Label Comparative Study Of De Novo Renal Allograft Recipients Receiving CSA + MMF + Corticosteroids Versus CSA + Rapamune + Corticosteroids Completed NCT01601821 Phase 4
6 IPT of Malaria With SP in Different Zones of Drug Resistance in Rwanda Completed NCT00372632 Phase 4
7 Effects of Transfusion Thresholds on Neurocognitive Outcome of Extremely Low Birth Weight Infants Active, not recruiting NCT01393496 Phase 4
8 Prevention of P. Vivax Malaria During Pregnancy in Bolivia Withdrawn NCT00290420 Phase 4
9 Premature Infants in Need of Transfusion (PINT) Completed NCT00182390 Phase 3
10 Early Detection of Anaemia During the Maternity Completed NCT00827463 Phase 3
11 Randomized Trial of Iron Supplementation to Prevent Anemia in Very-low-birth-weight Infants Completed NCT01224236 Phase 2, Phase 3
12 Doppler or Amniocentesis to Predict Fetal Anemia Completed NCT00295516 Phase 3
13 The Effects of Erythropoietin (EPO) on the Transfusion Requirements of Very Low Birth Weight Infants Completed NCT01203514 Phase 2, Phase 3
14 Establishing Effectiveness of Daily Co-trimoxazole Prophylaxis For Prevention of Malaria in Pregnancy Completed NCT01053325 Phase 3
15 Eculizumab to Treat Paroxysmal Nocturnal Hemoglobinuria Completed NCT00098280 Phase 3
16 Eculizumab to Treat Paroxysmal Nocturnal Hemoglobinuria Completed NCT00130000 Phase 3
17 Gestational Sulfadoxine-pyrimethamine and Azithromycin Treatment to Prevent Preterm Birth Completed NCT00131235 Phase 3
18 Safety and Efficacy Study of Oral Ferric Iron To Treat Iron Deficiency Anaemia in Quiescent Crohn's Disease (AEGIS-2) Completed NCT01352221 Phase 3
19 Safety and Efficacy Study of Oral Ferric Iron To Treat Iron Deficiency Anaemia in Quiescent Ulcerative Colitis (AEGIS-1) Completed NCT01340872 Phase 3
20 Intermittent Preventive Treatment (IPTp) Versus Rapid Diagnostic Testing (RDT) and Treatment of Malaria in Pregnancy Completed NCT00432367 Phase 3
21 Efficacy,Safety and Tolerability of Dihydroartemisinin-Piperaquine for Uncomplicated Malaria in Pregnancy in Ghana Completed NCT01231113 Phase 3
22 Intermittent Preventive Treatment During Pregnancy in Benin Completed NCT00274235 Phase 3
23 Impact of Prenatal Vitamin/Mineral Supplements on Perinatal Mortality Completed NCT00133744 Phase 3
24 Chloroquine for Malaria in Pregnancy Completed NCT01443130 Phase 3
25 Supplementing Maternal and Infant Diet With High-energy, Micronutrient Fortified Lipid-based Nutrient Supplements (LNS) Completed NCT01239693 Phase 3
26 Combination Treatment With and Without Protease Inhibitors for Women Who Begin Therapy for HIV Infection During Pregnancy Completed NCT00017719 Phase 3
27 Comparison of Anti-HIV Drug Combinations to Prevent Mother-to-Child Transmission of HIV Completed NCT00086359 Phase 3
28 Randomised Trial of 3 Artemisinin Combination Therapy for Malaria in Pregnancy Completed NCT01054248 Phase 3
29 Prevention of Pregnancy-associated Malaria in HIV-infected Women: Cotrimoxazole Prophylaxis Versus Mefloquine Completed NCT00970879 Phase 3
30 Protease Inhibitors to Reduce Malaria Morbidity in HIV-Infected Pregnant Women Completed NCT00993031 Phase 3
31 Transfusion of Prematures Trial Recruiting NCT01702805 Phase 3
32 Safety and Efficacy Study of BCD-066 Compared to Aranesp® for Anemia Treatment in Chronic Kidney Disease Patients Recruiting NCT02506868 Phase 3
33 Oxygen Therapy and Pregnancy in Sickle Cell Disease Recruiting NCT02813850 Phase 3
34 Impact of Pre-pregnancy Micronutrient Supplementation on Maternal and Child Outcomes Active, not recruiting NCT01665378 Phase 3
35 Randomized Trial: Maternal Vitamin D Supplementation to Prevent Childhood Asthma (VDAART) Active, not recruiting NCT00920621 Phase 3
36 Daily Co-trimoxazole Prophylaxis to Prevent Malaria in Pregnancy Terminated NCT00711906 Phase 3
37 Darbepoetin Administration to Preterm Infants Unknown status NCT00334737 Phase 2
38 Recombinant Erythropoietin for Neuroprotection in Very Preterm Infants Unknown status NCT00910234 Phase 1, Phase 2
39 Milking the Umbilical Cord Versus Immediate Clamping in Pre-term Infants < 33 Weeks Unknown status NCT01819532 Phase 2
40 Immediate VS Delayed Cord Clamping on Newborns Unknown status NCT01029496 Phase 1, Phase 2
41 Neurological Outcome After Erythropoietin Treatment for Neonatal Encephalopathy Completed NCT00808704 Phase 1, Phase 2
42 Impact of One Versus Two Amino Acid Chelated Iron Capsules on Prevention of Iron Deficiency Anemia in Non-anemic Women With Twin Gestations Completed NCT02858505 Phase 2
43 Randomized Study of Weekly Erythropoietin Dosing in Preterm Infants Completed NCT01235923 Phase 2
44 Red Blood Cell (RBC) Survival Following Transfusion in Infants Completed NCT00731588 Phase 2
45 A Study of Mircera in Anemic Patients With Non-Small Cell Lung Cancer Receiving First Line Chemotherapy. Completed NCT00327535 Phase 2
46 Pegylated Interferon Alfa-2a Maintenance Therapy and Liver Disease Progression in People Infected With Both HIV and Hepatitis C Virus (HCV) Completed NCT00078403 Phase 2
47 Optimized Erythropoietin (EPO) Treatment Recruiting NCT02075970 Phase 2
48 The Effect of Adjunctive Use of Vaginal Progesterone After Cerclage on Prevention of 2nd Trimester Miscarriage Recruiting NCT02846909 Phase 2
49 The Study on Umbilical Cord Milking to Prevent and Decrease the Severity of Anemia in Preterms Not yet recruiting NCT03023917 Phase 1, Phase 2
50 The Effect of Iron Deficiency Anemia During Pregnancy Not yet recruiting NCT02590224 Phase 2

Search NIH Clinical Center for Anemia of Prematurity

Genetic Tests for Anemia of Prematurity

Anatomical Context for Anemia of Prematurity

MalaCards organs/tissues related to Anemia of Prematurity:

39
Heart

Publications for Anemia of Prematurity

Articles related to Anemia of Prematurity:

(show top 50) (show all 97)
id Title Authors Year
1
Exploring the use of expanded erythroid cells for autologous transfusion for anemia of prematurity. ( 23521158 )
2013
2
Comparison of oral recombinant erythropoietin and subcutaneous recombinant erythropoietin in prevention of anemia of prematurity. ( 22737576 )
2012
3
Erythropoietin in anemia of prematurity. ( 23025776 )
2012
4
Necrotizing enterocolitis and the role of anemia of prematurity. ( 22818548 )
2012
5
Effect of short-term recombinant human erythropoietin therapy in the prevention of anemia of prematurity in very low birth weight neonates. ( 23540189 )
2012
6
Sucking improvement following blood transfusion for anemia of prematurity. ( 22664924 )
2012
7
Is there a role for autologous/placental red blood cell transfusions in the anemia of prematurity? ( 20303035 )
2010
8
Current controversies in the management of the anemia of prematurity. ( 19167579 )
2009
9
Erythrocyte transfusions and serum prohepcidin levels in premature newborns with anemia of prematurity. ( 19816209 )
2009
10
A clinical study on the feasibility of autologous cord blood transfusion for anemia of prematurity. ( 18507748 )
2008
11
Pathophysiology of Anemia During the Neonatal Period, Including Anemia of Prematurity. ( 20463861 )
2008
12
Controversies in the management of the anemia of prematurity using single-donor red blood cell transfusions and/or recombinant human erythropoietin. ( 16373186 )
2006
13
A randomized, controlled trial of the effects of adding vitamin B12 and folate to erythropoietin for the treatment of anemia of prematurity. ( 16818564 )
2006
14
Effects of transfusion in anemia of prematurity. ( 16166047 )
2005
15
Erythropoietin in anemia of prematurity. ( 12785302 )
2003
16
Iron status and the treatment of the anemia of prematurity. ( 12168242 )
2002
17
Does early erythropoietin therapy decrease transfusions in anemia of prematurity? ( 12061670 )
2002
18
Human recombinant erythropoietin in the prevention and treatment of anemia of prematurity. ( 11888358 )
2002
19
Anemia of prematurity. ( 12144218 )
2001
20
[The effect of recombinant human erythropoietin on the treatment of anemia of prematurity] ( 14647595 )
2001
21
Meta-analysis of controlled clinical trials studying the efficacy of rHuEPO in reducing blood transfusions in the anemia of prematurity. ( 11274599 )
2001
22
The role of high-dose oral iron supplementation during erythropoietin therapy for anemia of prematurity. ( 11533837 )
2001
23
Managing the anemia of prematurity: red blood cell transfusions versus recombinant erythropoietin. ( 11471123 )
2001
24
[Prophylaxis of anemia of prematurity with erythropoietin. Case control study]. ( 11083968 )
2000
25
Erythropoietin to prevent and treat the anemia of prematurity. ( 10202619 )
1999
26
Comparison between two and five doses a week of recombinant human erythropoietin for anemia of prematurity: a randomized trial. ( 10428996 )
1999
27
Recombinant human erythropoietin in anemia of prematurity. ( 10709119 )
1999
28
Financial impact of the introduction of erythropoietin in the treatment of anemia of premature infants in Israel. ( 10731302 )
1999
29
The use of erythropoietin in treatment of anemia of prematurity. ( 9601351 )
1998
30
Myocardial, erythropoietic, and metabolic adaptations to anemia of prematurity in infants with bronchopulmonary dysplasia. ( 9580761 )
1998
31
Recombinant human erythropoietin therapy for treatment of anemia of prematurity in very low birth weight infants: a randomized, double-blind, placebo-controlled trial. ( 9659643 )
1998
32
[Randomized multi-center trial of the administration of erythropoietin in anemia of prematurity]. ( 9297428 )
1997
33
The role of erythropoietin in the anemia of prematurity. ( 9190030 )
1997
34
Recombinant human erythropoietin as a treatment for anemia of prematurity. ( 9451192 )
1997
35
Recombinant erythropoietin for the anemia of prematurity: still a promise, not a panacea. ( 9403639 )
1997
36
Erythropoietin to treat anemia of prematurity. ( 9161667 )
1997
37
Erythropoietin therapy for anemia of prematurity. ( 8772909 )
1996
38
Effect of protein intake on erythropoiesis during erythropoietin treatment of anemia of prematurity. ( 8618185 )
1996
39
Do cardiac output and serum lactate levels indicate blood transfusion requirements in anemia of prematurity? ( 8796405 )
1996
40
Potential for treatment of anemia of prematurity with recombinant human erythropoietin. ( 7787927 )
1995
41
Use of epoetin (erythropoietin) in the anemia of prematurity. ( 7747503 )
1995
42
The effect of recombinant human erythropoietin in treating the anemia of prematurity. ( 7793277 )
1995
43
Follow-up of very low birth weight infants after erythropoietin treatment to prevent anemia of prematurity. ( 7636658 )
1995
44
[Effects of recombinant human erythropoietin in the treatment of anemia of prematurity]. ( 7739926 )
1995
45
Erythropoietin--not yet a standard treatment for anemia of prematurity. ( 7770317 )
1995
46
Pathophysiology and treatment of the anemia of prematurity. ( 7743231 )
1995
47
[Evaluation of treatment results for anemia of prematurity treated with various doses of human recombinant erythropoietin]. ( 8657506 )
1995
48
Recombinant human erythropoietin in the treatment of anemia of prematurity. ( 8540930 )
1995
49
A cost analysis comparing erythropoietin and red cell transfusions in the treatment of anemia of prematurity. ( 8604492 )
1995
50
Erythropoietin production by macrophages from preterm infants: implications regarding the cause of the anemia of prematurity. ( 8165050 )
1994

Variations for Anemia of Prematurity

Expression for Anemia of Prematurity

Search GEO for disease gene expression data for Anemia of Prematurity.

Pathways for Anemia of Prematurity

Pathways related to Anemia of Prematurity according to GeneCards Suite gene sharing:

(show all 16)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.47 CSF2 CSF3 EPO EPOR IL3 KITLG
2
Show member pathways
13.21 CSF2 CSF3 EPOR IL3 KITLG STAT5A
3 12.41 CSF3 EPO EPOR IL3 KITLG
4 12.34 IL3 KITLG STAT5A STAT5B
5
Show member pathways
12.05 EPO EPOR IL3 KITLG STAT5A STAT5B
6
Show member pathways
11.94 CSF2 CSF3 EPO EPOR IL3 STAT5A
7 11.8 CSF2 CSF3 EPO GYPA IL3 KITLG
8
Show member pathways
11.69 EPO EPOR STAT5A STAT5B
9
Show member pathways
11.66 IL3 STAT5A STAT5B
10 11.6 CSF2 STAT5A STAT5B
11 11.55 EPO EPOR IL3 STAT5A STAT5B
12 11.49 CSF2 CSF3 EPO EPOR GYPA IL3
13 11.35 EPO IL3 KITLG
14 11.09 CSF2 CSF3 IL3
15 10.85 CSF2 CSF3 EPO GYPA IL3 KITLG
16 10.84 STAT5A STAT5B

GO Terms for Anemia of Prematurity

Cellular components related to Anemia of Prematurity according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 CSF2 CSF3 EPO EPOR GPX3 HAMP
2 extracellular space GO:0005615 9.17 CSF2 CSF3 EPO GPX3 HAMP IL3

Biological processes related to Anemia of Prematurity according to GeneCards Suite gene sharing:

(show all 24)
id Name GO ID Score Top Affiliating Genes
1 peptidyl-tyrosine phosphorylation GO:0018108 9.83 CSF2 IL3 STAT5A STAT5B
2 cellular response to lipopolysaccharide GO:0071222 9.79 CSF2 CSF3 HAMP
3 cytokine-mediated signaling pathway GO:0019221 9.76 CSF3 EPOR IL3 STAT5B
4 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.75 CSF3 IL3 KITLG
5 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.65 CSF2 EPO IL3
6 positive regulation of cell proliferation GO:0008284 9.63 CSF2 CSF3 EPO IL3 KITLG STAT5B
7 response to vitamin A GO:0033189 9.61 EPO HAMP
8 positive regulation of Ras protein signal transduction GO:0046579 9.61 EPO KITLG
9 2-oxoglutarate metabolic process GO:0006103 9.6 STAT5A STAT5B
10 embryonic hemopoiesis GO:0035162 9.59 IL3 KITLG
11 JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 9.58 STAT5A STAT5B
12 oxaloacetate metabolic process GO:0006107 9.57 STAT5A STAT5B
13 creatine metabolic process GO:0006600 9.56 STAT5A STAT5B
14 succinate metabolic process GO:0006105 9.55 STAT5A STAT5B
15 citrate metabolic process GO:0006101 9.54 STAT5A STAT5B
16 valine metabolic process GO:0006573 9.51 STAT5A STAT5B
17 taurine metabolic process GO:0019530 9.49 STAT5A STAT5B
18 creatinine metabolic process GO:0046449 9.43 STAT5A STAT5B
19 isoleucine metabolic process GO:0006549 9.4 STAT5A STAT5B
20 erythropoietin-mediated signaling pathway GO:0038162 9.37 EPO EPOR
21 allantoin metabolic process GO:0000255 9.32 STAT5A STAT5B
22 prolactin signaling pathway GO:0038161 9.26 STAT5A STAT5B
23 positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 9.13 CSF2 EPO IL3
24 positive regulation of DNA replication GO:0045740 8.92 CSF2 EPO IL3 KITLG

Molecular functions related to Anemia of Prematurity according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.46 CSF2 CSF3 IL3 KITLG
2 Ras guanyl-nucleotide exchange factor activity GO:0005088 9.43 CSF2 IL3 KITLG
3 protein tyrosine kinase activity GO:0004713 9.26 CSF2 IL3 STAT5A STAT5B
4 growth factor activity GO:0008083 8.92 CSF2 CSF3 IL3 KITLG

Sources for Anemia of Prematurity

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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