MCID: ANM001
MIFTS: 35

Anemia of Prematurity malady

Fetal diseases, Blood diseases categories
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Summaries for Anemia of Prematurity

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65Wikipedia, 33MalaCards
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Wikipedia:65 Anemia of prematurity refers to a form of anemia affecting preterm infants with decreased hematocrit. more...

MalaCards: Anemia of Prematurity is related to blindness and 5q- syndrome. An important gene associated with Anemia of Prematurity is EPO (erythropoietin), and among its related pathways are Jak-STAT signaling pathway and Hematopoietic cell lineage. The compounds mitomycin c and bryostatin 1 have been mentioned in the context of this disorder. Affiliated tissues include heart, and related mouse phenotypes are cardiovascular system and integument.

Aliases & Classifications for Anemia of Prematurity

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8Disease Ontology, 62UMLS, 27ICD9CM, 58SNOMED-CT, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Fetal diseases
Anatomical: Blood diseases


Aliases & Descriptions:

anemia of prematurity 8


External Ids:

Disease Ontology8 DOID:11243
ICD9CM27 776.6
SNOMED-CT58 47100003
ICD1025 P61.2

Related Diseases for Anemia of Prematurity

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Anemia of Prematurity:



Diseases related to anemia of prematurity

Symptoms for Anemia of Prematurity

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Drugs & Therapeutics for Anemia of Prematurity

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Anemia of Prematurity

Search NIH Clinical Center for Anemia of Prematurity

Genetic Tests for Anemia of Prematurity

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Anatomical Context for Anemia of Prematurity

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33MalaCards
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MalaCards organs/tissues related to Anemia of Prematurity:

33
Heart

Animal Models for Anemia of Prematurity or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Anemia of Prematurity:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053858.5AREG, CSF2, EPO
2MP:00107718.2AREG, CSF2, EPO

Publications for Anemia of Prematurity

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52PubMed
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Articles related to Anemia of Prematurity:

(show top 50)    (show all 94)
idTitleAuthorsYear
1
Exploring the use of expanded erythroid cells for autologous transfusion for anemia of prematurity. (23521158)
2013
2
Erythropoietin in anemia of prematurity. (23025776)
2012
3
Effect of short-term recombinant human erythropoietin therapy in the prevention of anemia of prematurity in very low birth weight neonates. (23540189)
2012
4
Is there a role for autologous/placental red blood cell transfusions in the anemia of prematurity? (20303035)
2010
5
Current controversies in the management of the anemia of prematurity. (19167579)
2009
6
Pathophysiology of Anemia During the Neonatal Period, Including Anemia of Prematurity. (20463861)
2008
7
A clinical study on the feasibility of autologous cord blood transfusion for anemia of prematurity. (18507748)
2008
8
A randomized, controlled trial of the effects of adding vitamin B12 and folate to erythropoietin for the treatment of anemia of prematurity. (16818564)
2006
9
Effects of transfusion in anemia of prematurity. (16166047)
2005
10
Erythropoietin in anemia of prematurity. (12785302)
2003
11
Human recombinant erythropoietin in the prevention and treatment of anemia of prematurity. (11888358)
2002
12
Does early erythropoietin therapy decrease transfusions in anemia of prematurity? (12061670)
2002
13
The role of high-dose oral iron supplementation during erythropoietin therapy for anemia of prematurity. (11533837)
2001
14
Anemia of prematurity. (12144218)
2001
15
Managing the anemia of prematurity: red blood cell transfusions versus recombinant erythropoietin. (11471123)
2001
16
Meta-analysis of controlled clinical trials studying the efficacy of rHuEPO in reducing blood transfusions in the anemia of prematurity. (11274599)
2001
17
Recombinant human erythropoietin in anemia of prematurity. (10709119)
1999
18
Recombinant human erythropoietin therapy for treatment of anemia of prematurity in very low birth weight infants: a randomized, double-blind, placebo-controlled trial. (9659643)
1998
19
Erythropoietin to treat anemia of prematurity. (9161667)
1997
20
Recombinant erythropoietin for the anemia of prematurity: still a promise, not a panacea. (9403639)
1997
21
The role of erythropoietin in the anemia of prematurity. (9190030)
1997
22
Erythropoietin therapy for anemia of prematurity. (8772909)
1996
23
Erythropoietin--not yet a standard treatment for anemia of prematurity. (7770317)
1995
24
A cost analysis comparing erythropoietin and red cell transfusions in the treatment of anemia of prematurity. (8604492)
1995
25
Pathophysiology and treatment of the anemia of prematurity. (7743231)
1995
26
Evaluation of treatment results for anemia of prematurity treated with various doses of human recombinant erythropoietin]. (8657506)
1995
27
Use of epoetin (erythropoietin) in the anemia of prematurity. (7747503)
1995
28
The effect of recombinant human erythropoietin in treating the anemia of prematurity. (7793277)
1995
29
Follow-up of very low birth weight infants after erythropoietin treatment to prevent anemia of prematurity. (7636658)
1995
30
Blood transfusion in late anemia of prematurity: effect on oxygen consumption, heart rate, and weight gain in otherwise healthy infants. (7873916)
1994
31
Recombinant erythropoietin in anemia of prematurity: five years later. (8414840)
1993
32
Erythropoietin therapy for anemia of prematurity. (1552415)
1992
33
Recombinant erythropoietin compared with erythrocyte transfusion in the treatment of anemia of prematurity. (1941387)
1991
34
Use of recombinant erythropoietin in treatment of the anemia of prematurity. (1793163)
1991
35
Erythroid "burst promoting" activity in serum of patients with the anemia of prematurity. (2184214)
1990
36
Prediction of the need for transfusion during anemia of prematurity. (2184213)
1990
37
Circulating erythroid progenitors in the anemia of prematurity. (3627181)
1987
38
Lessons from the anemia of prematurity. (3329178)
1987
39
Anemia of prematurity. Current concepts in the issue of when to transfuse. (3513096)
1986
40
Erythropoietin and the anemia of prematurity. (4056994)
1985
41
Erythropoietin and the anemia of prematurity. (6502305)
1984
42
Anemia of prematurity: determinants of the erythropoietin response. (6502312)
1984
43
Plasma erythropoietin concentrations during the early anemia of prematurity. (6673483)
1983
44
The anemia of prematurity and the decision when to transfuse. (6369939)
1983
45
Anemia of prematurity. (7013658)
1981
46
The anemia of prematurity. Factors governing the erythropoietin response. (851485)
1977
47
Anemia of prematurity. (1167980)
1975
48
The anemia of prematurity. (13642236)
1959
49
Use of cobalt and iron in the treatment and prevention of anemia of prematurity. (14368067)
1955
50
Studies on the anemia of prematurity. (13206378)
1954

Variations for Anemia of Prematurity

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Expression for genes affiliated with Anemia of Prematurity

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Anemia of Prematurity

Search GEO for disease gene expression data for Anemia of Prematurity.

Pathways for genes affiliated with Anemia of Prematurity

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50PathCards, 30KEGG, 38NCBI BioSystems Database
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Pathways related to Anemia of Prematurity according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Type III interferon signaling38
9.0CSF2, EPO
29.0CSF2, EPO

Compounds for genes affiliated with Anemia of Prematurity

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45Novoseek, 11DrugBank, 29IUPHAR, 51PharmGKB, 61Tocris Bioscience, 3BitterDB, 24HMDB
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Compounds related to Anemia of Prematurity according to GeneCards/GeneDecks:

(show all 42)
idCompoundScoreTop Affiliating Genes
1mitomycin c459.7AREG, EPO
2bryostatin 1459.5AREG, CSF2
3pegfilgrastim45 1110.5CSF2, EPO
4anagrelide45 1110.5EPO, CSF2
5pixy321459.5CSF2, EPO
6amifostine45 1110.5CSF2, EPO
7filgrastim45 1110.4EPO, CSF2
8isoproterenol45 1110.4AREG, CSF2
9gm-csf45 2910.4CSF2, EPO
10methylcellulose459.4EPO, CSF2
11ribavirin45 51 1111.4CSF2, EPO
12melphalan45 51 1111.4CSF2, EPO
1312-o-tetradecanoylphorbol 13-acetate459.4AREG, CSF2
14bleomycin45 1110.4EPO, CSF2
15thalidomide45 51 61 1112.4CSF2, EPO
16sb 20358045 6110.4CSF2, AREG
17zidovudine45 51 1111.4CSF2, EPO
18carboplatin45 51 1111.4EPO, CSF2
19hydroxyurea45 51 1111.4CSF2, EPO
20gp 130459.4EPO, CSF2
21polysaccharide459.4CSF2, AREG
22cytarabine45 51 1111.4CSF2, EPO
23hydrocortisone45 3 61 1112.4EPO, CSF2
24inositol459.4CSF2, EPO
25norepinephrine45 24 1111.3AREG, CSF2
26gnrh459.3CSF2, EPO
27pd 98,059459.3CSF2, AREG
28butyrate459.3CSF2, EPO
29wortmannin459.3AREG, CSF2
30vitamin d459.3CSF2, EPO
31actinomycin d459.2CSF2, AREG
32pge2459.1AREG, CSF2
33cycloheximide459.1AREG, CSF2
34cyclosporin a45 29 6111.1CSF2, EPO
35calcitriol45 61 24 1111.9AREG, CSF2, EPO
36lactate458.9EPO, CSF2
37thymidine45 249.9AREG, CSF2, EPO
38cisplatin45 51 61 1111.9EPO, CSF2, AREG
39vegf458.9AREG, CSF2, EPO
40phosphatidylinositol458.9EPO, CSF2, AREG
41heparin45 29 24 1111.8AREG, CSF2
42tyrosine458.8EPO, CSF2, AREG

GO Terms for genes affiliated with Anemia of Prematurity

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16Gene Ontology
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Biological processes related to Anemia of Prematurity according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of cell proliferationGO:0082849.0CSF2, EPO
2positive regulation of tyrosine phosphorylation of Stat5 proteinGO:0425238.9CSF2, EPO
3positive regulation of DNA replicationGO:0457408.7CSF2, EPO

Products for genes affiliated with Anemia of Prematurity

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Anemia of Prematurity

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet