MCID: ANM001
MIFTS: 35

Anemia of Prematurity malady

Fetal diseases, Blood diseases categories

Summaries for Anemia of Prematurity

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66Wikipedia, 34MalaCards
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Wikipedia:66 Anemia of prematurity refers to a form of anemia affecting preterm infants with decreased hematocrit. more...

MalaCards: Anemia of Prematurity is related to blindness and 5q- syndrome. An important gene associated with Anemia of Prematurity is EPO (erythropoietin), and among its related pathways are Jak-STAT signaling pathway and Hematopoietic cell lineage. The compounds mitomycin c and bryostatin 1 have been mentioned in the context of this disorder. Affiliated tissues include heart, and related mouse phenotypes are cardiovascular system and integument.

Aliases & Classifications for Anemia of Prematurity

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9Disease Ontology, 63UMLS, 28ICD9CM, 59SNOMED-CT, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Fetal diseases
Anatomical: Blood diseases


Aliases & Descriptions:

anemia of prematurity 9


External Ids:

Disease Ontology9 DOID:11243
ICD9CM28 776.6
SNOMED-CT59 47100003
ICD1026 P61.2

Related Diseases for Anemia of Prematurity

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Anemia of Prematurity:



Diseases related to anemia of prematurity

Symptoms for Anemia of Prematurity

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Drugs & Therapeutics for Anemia of Prematurity

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Anemia of Prematurity

Drug clinical trials:

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Search NIH Clinical Center for Anemia of Prematurity

Search CenterWatch for Anemia of Prematurity

Genetic Tests for Anemia of Prematurity

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Anatomical Context for Anemia of Prematurity

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34MalaCards
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MalaCards organs/tissues related to Anemia of Prematurity:

34
Heart

Animal Models for Anemia of Prematurity or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Anemia of Prematurity:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053858.5AREG, CSF2, EPO
2MP:00107718.2AREG, CSF2, EPO

Publications for Anemia of Prematurity

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53PubMed
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Articles related to Anemia of Prematurity:

(show top 50)    (show all 94)
idTitleAuthorsYear
1
Exploring the use of expanded erythroid cells for autologous transfusion for anemia of prematurity. (23521158)
2013
2
Erythropoietin in anemia of prematurity. (23025776)
2012
3
Effect of short-term recombinant human erythropoietin therapy in the prevention of anemia of prematurity in very low birth weight neonates. (23540189)
2012
4
Is there a role for autologous/placental red blood cell transfusions in the anemia of prematurity? (20303035)
2010
5
Current controversies in the management of the anemia of prematurity. (19167579)
2009
6
Pathophysiology of Anemia During the Neonatal Period, Including Anemia of Prematurity. (20463861)
2008
7
A clinical study on the feasibility of autologous cord blood transfusion for anemia of prematurity. (18507748)
2008
8
A randomized, controlled trial of the effects of adding vitamin B12 and folate to erythropoietin for the treatment of anemia of prematurity. (16818564)
2006
9
Effects of transfusion in anemia of prematurity. (16166047)
2005
10
Erythropoietin in anemia of prematurity. (12785302)
2003
11
Human recombinant erythropoietin in the prevention and treatment of anemia of prematurity. (11888358)
2002
12
Does early erythropoietin therapy decrease transfusions in anemia of prematurity? (12061670)
2002
13
The role of high-dose oral iron supplementation during erythropoietin therapy for anemia of prematurity. (11533837)
2001
14
Anemia of prematurity. (12144218)
2001
15
Managing the anemia of prematurity: red blood cell transfusions versus recombinant erythropoietin. (11471123)
2001
16
Meta-analysis of controlled clinical trials studying the efficacy of rHuEPO in reducing blood transfusions in the anemia of prematurity. (11274599)
2001
17
Recombinant human erythropoietin in anemia of prematurity. (10709119)
1999
18
Recombinant human erythropoietin therapy for treatment of anemia of prematurity in very low birth weight infants: a randomized, double-blind, placebo-controlled trial. (9659643)
1998
19
Erythropoietin to treat anemia of prematurity. (9161667)
1997
20
Recombinant erythropoietin for the anemia of prematurity: still a promise, not a panacea. (9403639)
1997
21
The role of erythropoietin in the anemia of prematurity. (9190030)
1997
22
Erythropoietin therapy for anemia of prematurity. (8772909)
1996
23
Erythropoietin--not yet a standard treatment for anemia of prematurity. (7770317)
1995
24
A cost analysis comparing erythropoietin and red cell transfusions in the treatment of anemia of prematurity. (8604492)
1995
25
Pathophysiology and treatment of the anemia of prematurity. (7743231)
1995
26
Evaluation of treatment results for anemia of prematurity treated with various doses of human recombinant erythropoietin]. (8657506)
1995
27
Use of epoetin (erythropoietin) in the anemia of prematurity. (7747503)
1995
28
The effect of recombinant human erythropoietin in treating the anemia of prematurity. (7793277)
1995
29
Follow-up of very low birth weight infants after erythropoietin treatment to prevent anemia of prematurity. (7636658)
1995
30
Blood transfusion in late anemia of prematurity: effect on oxygen consumption, heart rate, and weight gain in otherwise healthy infants. (7873916)
1994
31
Recombinant erythropoietin in anemia of prematurity: five years later. (8414840)
1993
32
Erythropoietin therapy for anemia of prematurity. (1552415)
1992
33
Recombinant erythropoietin compared with erythrocyte transfusion in the treatment of anemia of prematurity. (1941387)
1991
34
Use of recombinant erythropoietin in treatment of the anemia of prematurity. (1793163)
1991
35
Erythroid "burst promoting" activity in serum of patients with the anemia of prematurity. (2184214)
1990
36
Prediction of the need for transfusion during anemia of prematurity. (2184213)
1990
37
Circulating erythroid progenitors in the anemia of prematurity. (3627181)
1987
38
Lessons from the anemia of prematurity. (3329178)
1987
39
Anemia of prematurity. Current concepts in the issue of when to transfuse. (3513096)
1986
40
Erythropoietin and the anemia of prematurity. (4056994)
1985
41
Erythropoietin and the anemia of prematurity. (6502305)
1984
42
Anemia of prematurity: determinants of the erythropoietin response. (6502312)
1984
43
Plasma erythropoietin concentrations during the early anemia of prematurity. (6673483)
1983
44
The anemia of prematurity and the decision when to transfuse. (6369939)
1983
45
Anemia of prematurity. (7013658)
1981
46
The anemia of prematurity. Factors governing the erythropoietin response. (851485)
1977
47
Anemia of prematurity. (1167980)
1975
48
The anemia of prematurity. (13642236)
1959
49
Use of cobalt and iron in the treatment and prevention of anemia of prematurity. (14368067)
1955
50
Studies on the anemia of prematurity. (13206378)
1954

Variations for Anemia of Prematurity

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Expression for genes affiliated with Anemia of Prematurity

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Anemia of Prematurity

Search GEO for disease gene expression data for Anemia of Prematurity.

Pathways for genes affiliated with Anemia of Prematurity

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51PathCards, 31KEGG, 39NCBI BioSystems Database
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Pathways related to Anemia of Prematurity according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Type III interferon signaling39
9.0CSF2, EPO
29.0CSF2, EPO

Compounds for genes affiliated with Anemia of Prematurity

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Sources:
46Novoseek, 12DrugBank, 30IUPHAR, 52PharmGKB, 62Tocris Bioscience, 3BitterDB, 25HMDB
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Compounds related to Anemia of Prematurity according to GeneCards/GeneDecks:

(show all 42)
idCompoundScoreTop Affiliating Genes
1mitomycin c469.7AREG, EPO
2bryostatin 1469.5AREG, CSF2
3pegfilgrastim46 1210.5CSF2, EPO
4anagrelide46 1210.5EPO, CSF2
5pixy321469.5CSF2, EPO
6amifostine46 1210.5CSF2, EPO
7filgrastim46 1210.4EPO, CSF2
8isoproterenol46 1210.4AREG, CSF2
9gm-csf46 3010.4CSF2, EPO
10methylcellulose469.4EPO, CSF2
11ribavirin46 52 1211.4CSF2, EPO
12melphalan46 52 1211.4CSF2, EPO
1312-o-tetradecanoylphorbol 13-acetate469.4AREG, CSF2
14bleomycin46 1210.4EPO, CSF2
15thalidomide46 52 62 1212.4CSF2, EPO
16sb 20358046 6210.4CSF2, AREG
17zidovudine46 52 1211.4CSF2, EPO
18carboplatin46 52 1211.4EPO, CSF2
19hydroxyurea46 52 1211.4CSF2, EPO
20gp 130469.4EPO, CSF2
21polysaccharide469.4CSF2, AREG
22cytarabine46 52 1211.4CSF2, EPO
23hydrocortisone46 3 62 1212.4EPO, CSF2
24inositol469.4CSF2, EPO
25norepinephrine46 25 1211.3AREG, CSF2
26gnrh469.3CSF2, EPO
27pd 98,059469.3CSF2, AREG
28butyrate469.3CSF2, EPO
29wortmannin469.3AREG, CSF2
30vitamin d469.3CSF2, EPO
31actinomycin d469.2CSF2, AREG
32pge2469.1AREG, CSF2
33cycloheximide469.1AREG, CSF2
34cyclosporin a46 30 6211.1CSF2, EPO
35calcitriol46 62 25 1211.9AREG, CSF2, EPO
36lactate468.9EPO, CSF2
37thymidine46 259.9AREG, CSF2, EPO
38cisplatin46 52 62 1211.9EPO, CSF2, AREG
39vegf468.9AREG, CSF2, EPO
40phosphatidylinositol468.9EPO, CSF2, AREG
41heparin46 30 25 1211.8AREG, CSF2
42tyrosine468.8EPO, CSF2, AREG

GO Terms for genes affiliated with Anemia of Prematurity

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17Gene Ontology
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Biological processes related to Anemia of Prematurity according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of cell proliferationGO:0082849.0CSF2, EPO
2positive regulation of tyrosine phosphorylation of Stat5 proteinGO:0425238.9CSF2, EPO
3positive regulation of DNA replicationGO:0457408.7CSF2, EPO

Products for genes affiliated with Anemia of Prematurity

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Anemia of Prematurity

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet