Aliases & Classifications for Aneurysm

MalaCards integrated aliases for Aneurysm:

Name: Aneurysm 50 28 51 69 59
Aneurysms 40

Summaries for Aneurysm

NINDS : 50 A cerebral aneurysm is a weak or thin spot on a blood vessel in the brain that balloons out and fills with blood.  An aneurysm can press on a nerve or surrounding tissue, and also leak or burst, which lets blood spill into surrounding tissues (called a hemorrhage). Cerebral aneurysms can occur at any age, although they are more common in adults than in children and are slightly more common in women than in men.  The signs and symptoms of an unruptured cerebral aneurysm will partly depend on its size and rate of growth. For example, a small, unchanging aneurysm will generally produce no symptoms, whereas a larger aneurysm that is steadily growing may produce symptoms such as headache, numbness, loss of feeling in the face or problems with the eyes. Immediately after an aneurysm ruptures, an individual may experience such symptoms as a sudden and unusually severe headache, nausea, vision impairment, vomiting, and loss of consciousness.

MalaCards based summary : Aneurysm, also known as aneurysms, is related to intracranial aneurysm and familial thoracic aortic aneurysm and dissection, and has symptoms including edema, chest pain and angina pectoris. An important gene associated with Aneurysm is TGFBR2 (Transforming Growth Factor Beta Receptor 2), and among its related pathways/superpathways are ERK Signaling and PAK Pathway. The drugs Heparin and Dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include bone, endothelial and heart, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

MedlinePlus : 40 An aneurysm is a bulge or "ballooning" in the wall of an artery. Arteries are blood vessels that carry oxygen-rich blood from the heart to other parts of the body. If an aneurysm grows large, it can burst and cause dangerous bleeding or even death. Most aneurysms occur in the aorta, the main artery that runs from the heart through the chest and abdomen. Aneurysms also can happen in arteries in the brain, heart and other parts of the body. If an aneurysm in the brain bursts, it causes a stroke. Aneurysms can develop and become large before causing any symptoms. Often doctors can stop aneurysms from bursting if they find and treat them early. They use imaging tests to find aneurysms. Often aneurysms are found by chance during tests done for other reasons. Medicines and surgery are the two main treatments for aneurysms. NIH: National Heart, Lung, and Blood Institute

PubMed Health : 59
About aneurysm: An aneurysm (AN-u-rism) is a balloon-like bulge in an artery. Arteries are blood vessels that carry oxygen-rich blood to your body.Arteries have thick walls to withstand normal blood pressure. However, certain medical problems, genetic conditions, and trauma can damage or injure artery walls. The force of blood pushing against the weakened or injured walls can cause an aneurysm.An aneurysm can grow large and rupture (burst) or dissect. A rupture causes dangerous bleeding inside the body. A dissection is a split in one or more layers of the artery wall. The split causes bleeding into and along the layers of the artery wall.Both rupture and dissection often are fatal.

Related Diseases for Aneurysm

Diseases related to Aneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 987)
# Related Disease Score Top Affiliating Genes
1 intracranial aneurysm 34.0 CDKN2B-AS1 ELN LOX
2 familial thoracic aortic aneurysm and dissection 33.9 SMAD3 TGFBR1 TGFBR2
3 subclavian artery aneurysm 33.0 MYH11 TGFBR2
4 loeys-dietz syndrome 32.8 ACTA2 SMAD3 TGFB2 TGFBR1 TGFBR2
5 intracranial berry aneurysm 32.5 ANIB1 ANIB2 ANIB3 ANIB4
6 arterial tortuosity syndrome 31.7 EFEMP2 ELN TGFBR1
7 aortic aneurysm, familial thoracic 1 31.1 AAT1 ACTA2 EFEMP2 ELN MFAP5 MYH11
8 marfan syndrome 30.7 ACTA2 ELN TGFBR1 TGFBR2
9 aortic aneurysm 30.5 AAT1 ACTA2 EFEMP2 ELN FOXE3 LOX
10 hereditary hemorrhagic telangiectasia 30.1 TGFB2 TGFBR1 TGFBR2
11 aortic disease 29.5 ACTA2 ELN PRKG1 TGFB2 TGFBR1 TGFBR2
12 cerebral arterial disease 29.3 ACTA2 CDKN2B-AS1 ELN
13 aortic aneurysm, familial abdominal, 1 12.6
14 aneurysmal bone cysts 12.3
15 cerebral aneurysms 12.3
16 heart aneurysm 12.3
17 coronary artery aneurysm 12.3
18 aortic aneurysm, familial thoracic 4 12.2
19 vein of galen aneurysm 12.2
20 aneurysm of sinus of valsalva 12.2
21 angiopathy, hereditary, with nephropathy, aneurysms, and muscle cramps 12.2
22 aneurysm, intracranial berry, 4 12.1
23 aneurysm, intracranial berry, 2 12.1
24 aortic aneurysm, familial thoracic 10 12.1
25 aortic aneurysm, familial thoracic 6 12.1
26 aortic aneurysm, familial thoracic 7 12.1
27 aortic aneurysm, familial thoracic 9 12.1
28 aortic aneurysm, familial thoracic 11 12.1
29 aneurysm, intracranial berry, 5 12.1
30 coronary aneurysm 12.0
31 aneurysm, intracranial berry, 9 12.0
32 aneurysm, intracranial berry, 11 12.0
33 aneurysm, intracranial berry, 10 12.0
34 aneurysm, intracranial berry, 6 12.0
35 aneurysm, intracranial berry, 7 12.0
36 aneurysm, intracranial berry, 8 12.0
37 aneurysm, intracranial berry, 3 12.0
38 aortic aneurysm, familial thoracic 8 12.0
39 aneurysm, intracranial berry, 1 12.0
40 splenic artery aneurysm 12.0
41 atrial septal aneurysm 12.0
42 familial abdominal aortic aneurysm 12.0
43 familial cerebral saccular aneurysm 11.9
44 aneurysm of interventricular septum 11.9
45 loeys-dietz syndrome 1 11.9
46 extracranial carotid artery aneurysm 11.8
47 berry aneurysm, cirrhosis, pulmonary emphysema, and cerebral calcification 11.8
48 congenital coronary artery aneurysm 11.8
49 aortic aneurysm, familial abdominal, 2 11.8
50 aortic aneurysm, familial abdominal, 3 11.8

Graphical network of the top 20 diseases related to Aneurysm:



Diseases related to Aneurysm

Symptoms & Phenotypes for Aneurysm

UMLS symptoms related to Aneurysm:


edema, chest pain, angina pectoris

GenomeRNAi Phenotypes related to Aneurysm according to GeneCards Suite gene sharing:

25 (show all 20)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-104 9.72 TGFBR2
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-14 9.72 TGFB2
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-141 9.72 TGFB2
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-145 9.72 PRKG1 TGFBR2
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.72 TGFBR2
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-165 9.72 TGFBR2 TGFBR1
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.72 TGFBR1
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-20 9.72 TGFBR2
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.72 TGFBR1
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-216 9.72 PRKG1
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-26 9.72 TGFB2
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-48 9.72 TGFBR2
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-59 9.72 TGFB2
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-60 9.72 TGFBR2 PRKG1 TGFB2 TGFBR1
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-65 9.72 TGFBR2
16 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.72 TGFB2
17 Decreased shRNA abundance (Z-score < -2) GR00366-A-72 9.72 TGFB2
18 Decreased shRNA abundance (Z-score < -2) GR00366-A-75 9.72 PRKG1
19 Decreased shRNA abundance (Z-score < -2) GR00366-A-77 9.72 TGFBR1
20 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.72 TGFBR2

MGI Mouse Phenotypes related to Aneurysm:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.03 ACTA2 EFEMP2 LOX MFAP5 MMP12 MYH11
2 digestive/alimentary MP:0005381 9.7 MYH11 MYLK PRKG1 SMAD3 TGFB2 TGFBR1
3 muscle MP:0005369 9.61 ACTA2 EFEMP2 LOX MYH11 MYLK PRKG1
4 respiratory system MP:0005388 9.17 TGFBR2 EFEMP2 LOX MMP12 MYH11 TGFB2

Drugs & Therapeutics for Aneurysm

PubMedHealth treatment related to Aneurysm: 59

Aortic aneurysms are treated with medicines and surgery. Small aneurysms that are found early and aren’t causing symptoms may not need treatment. Other aneurysms need to be treated.The goals of treatment may include:Preventing the aneurysm from growingPreventing or reversing damage to other body structuresPreventing or treating a rupture or dissectionAllowing you to continue doing your normal daily activitiesTreatment for an aortic aneurysm is based on its size. Your doctor may recommend routine testing to make sure an aneurysm isn't getting bigger. This method usually is used for aneurysms that are smaller than 5 centimeters (about 2 inches) across.How often you need testing (for example, every few months or every year) is based on the size of the aneurysm and how fast it's growing. The larger it is and the faster it's growing, the more often you may need to be checked.

Drugs for Aneurysm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 687)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 46507594 772
2
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
3
Simvastatin Approved Phase 4,Phase 3,Phase 2 79902-63-9 54454
4
Zinc Approved, Investigational Phase 4,Phase 1,Early Phase 1 7440-66-6 32051 23994
5
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-78-2 2244
6
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 50-28-2 5757
7
Paclitaxel Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 33069-62-4 36314
8
Ritonavir Approved, Investigational Phase 4 155213-67-5 392622
9
Lopinavir Approved Phase 4 192725-17-0 92727
10
Midazolam Approved, Illicit Phase 4,Phase 2 59467-70-8 4192
11
Iron Approved Phase 4,Phase 2,Phase 1 7439-89-6 23925
12
Morphine Approved, Investigational Phase 4,Phase 3 57-27-2 5288826
13
Acetaminophen Approved Phase 4,Phase 3,Phase 2 103-90-2 1983
14
Nifedipine Approved Phase 4,Phase 1 21829-25-4 4485
15
Ramipril Approved Phase 4 87333-19-5 5362129
16
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
17
Amlodipine Approved Phase 4,Phase 3,Phase 2 88150-42-9 2162
18
Irbesartan Approved, Investigational Phase 4,Phase 3 138402-11-6 3749
19
Atenolol Approved Phase 4,Phase 3 29122-68-7 2249
20
Clopidogrel Approved Phase 4,Phase 3 120202-66-6, 113665-84-2 60606
21
Adalimumab Approved Phase 4,Phase 3 331731-18-1 16219006
22
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
23
Misoprostol Approved Phase 4,Phase 3,Phase 2,Phase 1 59122-46-2 5282381
24
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 76631-46-4, 113775-47-6 5311068 56032 68602
25
Angiotensin II Approved, Investigational Phase 4,Phase 3,Phase 2 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
26
Abacavir Approved, Investigational Phase 4 136470-78-5 441300 65140
27
Prednisolone Approved, Vet_approved Phase 4,Phase 1 50-24-8 5755
28
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 22916-47-8 4189
29
Sevoflurane Approved, Vet_approved Phase 4,Phase 3,Phase 2 28523-86-6 5206
30
Lidocaine Approved, Vet_approved Phase 4,Phase 3 137-58-6 3676
31
Lactulose Approved Phase 4 4618-18-2 11333
32
Nandrolone decanoate Approved, Illicit Phase 4 360-70-3 9677
33
Acetazolamide Approved, Vet_approved Phase 4,Phase 2 59-66-5 1986
34
Nandrolone Approved, Experimental, Illicit, Investigational Phase 4 62-90-8, 434-22-0 9904 229455
35
Oxytocin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-56-6 53477758 439302
36
Bupivacaine Approved, Investigational Phase 4,Phase 1 38396-39-3, 2180-92-9 2474
37
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2 1197-18-8 5526
38
Chromium Approved Phase 4,Phase 3 7440-47-3 27668
39
Everolimus Approved Phase 4,Phase 3,Phase 1,Phase 2 159351-69-6 6442177
40
Maraviroc Approved, Investigational Phase 4 376348-65-1 3002977
41
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 2078-54-8 4943
42
Paroxetine Approved, Investigational Phase 4 61869-08-7 43815
43
Dimethyl fumarate Approved, Investigational Phase 4 624-49-7 5271565 637568
44
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
45
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1 1994-09-7, 94-09-7 2337
46
Menthol Approved Phase 4,Phase 3 2216-51-5 16666
47
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
48
Methylene blue Approved, Investigational Phase 4 61-73-4
49
Methylprednisolone Approved, Vet_approved Phase 4,Phase 1 83-43-2 6741
50
Clevidipine Approved, Investigational Phase 4,Phase 2 167221-71-8

Interventional clinical trials:

(show top 50) (show all 1710)

# Name Status NCT ID Phase Drugs
1 Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization Unknown status NCT01029938 Phase 4
2 Prophylactic Mesh Implantation After Abdominal Aortic Aneurysm Repair Unknown status NCT01353443 Phase 4
3 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4 herbal drug;placebo
4 Post-dilatation for Optimization of Drug-eluting Stents (DES) Deployment Assessed by Intravascular Ultrasound Multicenter Analysis Unknown status NCT01103765 Phase 4
5 Comparison of Beta-blocker Versus Angiotensin Receptor Blocker for Suppression of Aneurysm Expansion in Patients With Small Abdominal Aortic Aneurysm and Hypertension (BASE Trial) Unknown status NCT01904981 Phase 4 Beta-blocker-Atenolol 50mg, PO(peroral), Once daily;Angiotensin receptor blocker-Valsartan 80mg, PO(peroral), Once daily
6 Immunonutrition and Thoracoabdominal Aorta Aneurysm Repair Unknown status NCT00339053 Phase 4 Immunonutrition ( Impact)
7 Effectiveness of Acetazolamide in Reducing Paralysis of the Leg in Patients Undergoing Aortic Aneurysm Surgery Surgery Unknown status NCT01889498 Phase 4 Acetazolamide
8 HYdrogel Coil Versus Bare Platinum Coil in Recanalization Imaging Data Study Unknown status NCT01516658 Phase 4
9 Prophylactic Lidocaine Spray for Pain Alleviation in Women Undergoing Osmotic Dilator Insertion for Second Trimester Dilatation and Evacuation Unknown status NCT02097017 Phase 4 Lidocaine
10 Intravaginal Misoprostol Versus Dinoprostone Before Diagnostik Hysteroscopy Unknown status NCT01620814 Phase 4 Dinoprostone;misoprostol;control
11 The Influence of Adalimumab on Cardiovascular and Metabolic Risk in Psoriasis Unknown status NCT01088165 Phase 4 Adalimumab treatment arm;Fumaric acid esters treatment group
12 Effect of the Length of Second Stage of Labor in Primigravidae on Maternal & Neonatal Outcomes Unknown status NCT02676505 Phase 4
13 Arterial Catheter to Monitor Glycemia Unknown status NCT01176279 Phase 4
14 The Maternal and Perinatal Outcomes Associated With the Use of Non-pharmacological in Labor Unknown status NCT01601860 Phase 4
15 Tranexamic Acid in Major Vascular Surgery Unknown status NCT02335359 Phase 4 tranexamic acid diluted in 100 ml of saline solution (loading dose);tranexamic acid undiluted (continous infusion);Placebo
16 Maraviroc Abacavir STudy - Effect on Endothelial Recovery Unknown status NCT01389063 Phase 4 Maraviroc
17 Apposition Assessed Using Optical Coherence Tomography of Chromium Stents Eluting Everolimus From Cobalt Versus Platinum Alloy Platforms Unknown status NCT01776567 Phase 4
18 Pilot Study of Lovaza (Omega 3 Fatty Acids) to Improve Cardiac Antioxidant/Anti-inflammatory Profile Before Cardiac Surgery Unknown status NCT01046604 Phase 4 Lovaza group
19 Efficacy of Xience/Promus Versus Cypher in rEducing Late Loss After stENTing Unknown status NCT00698607 Phase 4 6-month clopidogrel therapy;12-month clopidogrel therapy
20 The Effects of AST-120 on Endothelial Dysfunction in Patients With Chronic Kidney Disease Unknown status NCT01157260 Phase 4 Kremezin
21 Effects and Underlying Mechanism of Lipid Lowering Intervention on Vascular Protection in Hypertensive Patients Unknown status NCT02254824 Phase 4 Xuezhikang;Atorvastatin
22 Prevena Vascular Groin Wound Study Unknown status NCT02581904 Phase 4
23 RAltegravir Switch STudy: Effects on Endothelial Recovery Unknown status NCT01453933 Phase 4 raltegravir
24 Prospective, Multicenter Study of the Second Generation Antimicrobial Graft in the Abdominal Position Unknown status NCT00824109 Phase 4
25 Study to Investigate the Effect of Heart Rate Reduction With Ivabradine on Vascular Elastic Properties and Endothelial Function in Patients With Stable Coronary Heart Disease Unknown status NCT01768585 Phase 4 Ivabradine;Placebo
26 Chronic Treatment With Benfotiamine Restores Endothelial Function in People With Type 2 Diabetes Mellitus Unknown status NCT00446810 Phase 4 Benfotiamine;Placebo
27 Targeting Microvascular Dysfunction in Young Hypertensive Patients Unknown status NCT01047423 Phase 4 Simvastatin;Placebo
28 Paroxetines Effect on Tramadols Metabolism and Pharmakodynamics: a Dose Response Study Unknown status NCT00785603 Phase 4 Paroxetine;Paroxetin placebo;Tramadol
29 Intravenous-Morphine and Glucagon-Usage Enhanced MR Cholangiography Unknown status NCT00155376 Phase 4 morphine and glucagon
30 Effect of Invasive and Non Invasive Mechanical Ventilation on Feeding Delivery in COPD Elderly Patients Unknown status NCT00417755 Phase 4
31 Effect of BNP (Brain Natriuretic Peptides) on Endothelial Dysfunction Induced by Coronary Angioplasty Unknown status NCT00262574 Phase 4 Nesiritide,
32 Personalized Peroral Endoscopic Myotomy for Achalasia Unknown status NCT01570621 Phase 4
33 Minimum Effective Dose (MED) & Epidural Bupivacaine Unknown status NCT02116842 Phase 4 0.1% bupivacaine;0.075% bupivacaine;40 µg fentanyl
34 Medical and Endovascular Treatment of Atherosclerotic Renal Artery Stenosis (METRAS Study) Unknown status NCT01208714 Phase 4 Optimal medical therapy
35 Study of Endothelial Dysfunction in Systemic Lupus and Its Role in Heart Disease Unknown status NCT00188188 Phase 4 quinipril
36 A Study of Nifecardia SRFC and Adalat OROS in the Treatment of Patients With Essential Hypertension Unknown status NCT00173667 Phase 4 Nifedipine 30 mg GITS
37 Quadratus Lumborum Block for Percutaneous Nephrostomy Unknown status NCT02121951 Phase 4 MAC
38 Efficacy of Induction of Labor on Term Using a Double Balloon Catheter Compared to Dinoprostone Vaginal-insert Unknown status NCT01720394 Phase 4 Dinoprostone
39 Statin and Angiotensin-converting Enzyme Inhibitor on Symptoms in Patients With SCAD Unknown status NCT02008786 Phase 4 ramipril;rosuvastatin;placebo
40 Effect Of Intra-muscular Administration of Dexamethasone in Induction of Labour Unknown status NCT02508402 Phase 4 Dexamethasone;Placebo
41 Endometrial Preparation Before Operative Hysteroscopy in Premenopausal Women Unknown status NCT02440750 Phase 4 Dienogest;Ulipristal acetate
42 PRotective Effect on the Coronary Microcirculation of Patients With DIabetes by Clopidogrel or Ticagrelor Unknown status NCT02698618 Phase 4 Randomization
43 A Morbidity-Mortality and Remodeling Study With Valsartan Unknown status NCT00133328 Phase 4 valsartan
44 Aneurysm Wall Histology Registry Completed NCT01444664 Phase 4
45 MAPS Trial: Matrix And Platinum Science Completed NCT00396981 Phase 4
46 Endovascular Repair of Descending Thoracic Aortic Aneurysms Completed NCT00802984 Phase 4
47 Endovascular Repair of Abdominal Aortic Aneurysms Completed NCT00803075 Phase 4
48 GORE EXCLUDER® Endoprosthesis - Low Permeability in Treatment of Abdominal Aortic Aneurysms Completed NCT00593814 Phase 4
49 Study of the Effectiveness of Telmisartan in Slowing the Progression of Abdominal Aortic Aneurysms Completed NCT01683084 Phase 4 Telmisartan;Placebo
50 TRAIL: Treatment of Intracranial Aneurysms With LVIS® System Completed NCT02921711 Phase 4

Search NIH Clinical Center for Aneurysm

Genetic Tests for Aneurysm

Genetic tests related to Aneurysm:

# Genetic test Affiliating Genes
1 Aneurysm 28

Anatomical Context for Aneurysm

MalaCards organs/tissues related to Aneurysm:

38
Bone, Endothelial, Heart, Brain, Kidney, Spinal Cord, Testes

Publications for Aneurysm

Articles related to Aneurysm:

(show top 50) (show all 8911)
# Title Authors Year
1
Bronchial perforation with aortic pseudo-aneurysm due to aspirated foreign body. ( 29436072 )
2018
2
Congenital aneurysm of both left ventricle and left atrium. ( 29440840 )
2018
3
Aneurysm of the inferior vena cava with thrombosis. ( 29445486 )
2018
4
A custom-made TreovanceAr abdominal aortic aneurysm endograft to correct late failure of trombone technique with a tube endograft. ( 29421425 )
2018
5
Thrombotic Occlusion and Revascularization of a Left Main Coronary Artery Aneurysm Years After Surgical Closure of LeftA Coronary-to-Right Ventricle Fistula. ( 29361450 )
2018
6
Stent-assisted coil embolization on down-the-barrel view with spring-shaped microcatheter in patient with M1 ultrawide necked circumferential aneurysm. ( 29444960 )
2018
7
Surgery of giant right coronary artery aneurysm complicated with coronary artery fistula to left ventricle. ( 29415369 )
2018
8
A rare case of massive lower gastrointestinal bleeding from a ruptured splenic artery aneurysm. ( 29423167 )
2018
9
True aneurysm of the proximal occipital artery: Case report. ( 29438855 )
2018
10
Endovascular treatment of cerebral aneurysm after renal transplantation in polycystic kidney disease. ( 29444616 )
2018
11
Azygos continuation of the caudal vena cava with segmental aneurysm, lung lobe torsion and pulmonary thromboembolism in a dog. ( 29445478 )
2018
12
Cyclic Mechanical Stretch Induced Smooth Muscle Cell Changes in Cerebral Aneurysm Progress by Reducing Collagen Type IV and Collagen Type VI Levels. ( 29439246 )
2018
13
Axillary artery aneurysm combined with brachial plexus palsy due to Takayasu arteritis. ( 29305362 )
2018
14
Aortic Coarctation Complicated with Intracranial Aneurysm: A Case Report and Literature Review. ( 29325938 )
2018
15
Renal Fenestration Closure Technique in fenestrated endovascular repair for para-renal aortic aneurysm. ( 29421424 )
2018
16
Reduced Intravoxel Incoherent Motion Microvascular Perfusion Predicts Delayed Cerebral Ischemia and Vasospasm After Aneurysm Rupture. ( 29439196 )
2018
17
Rupture of an Abdominal Aortic Aneurysm in a Young Man with Marfan Syndrome. ( 29421423 )
2018
18
Hemodynamic characteristics of hyperplastic remodeling lesions in cerebral aneurysms. ( 29338059 )
2018
19
Case Image: Percutaneous approach to giant coronary artery aneurysm: successful implantation of covered stent graft. ( 29339680 )
2018
20
Pathogenesis of idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) or 'idiopathic retinal arteriolar aneurysms (IRAA)' with macular star. ( 29447942 )
2018
21
Clinical outcomes of total endovascular aneurysm repair for aortic aneurysms involving the proximal anastomotic aneurysm following initial open repair for infrarenal abdominal aortic aneurysm. ( 29421415 )
2018
22
Secondary coiling after incomplete surgical clipping of cerebral aneurysms: a rescue strategy or a treatment option for complex cases? Institutional series and systematic review. ( 29417290 )
2018
23
Rare Coding Variants in ANGPTL6 Are Associated with Familial Forms of Intracranial Aneurysm. ( 29304371 )
2018
24
Phase-contrast MRI versus numerical simulation to quantify hemodynamical changes in cerebral aneurysms after flow diverter treatment. ( 29304062 )
2018
25
Coronary Artery Aneurysm Formation: Kawasaki Disease versus Atherosclerosis. ( 29320319 )
2018
26
Defective p27 phosphorylation at serine 10 affects vascular reactivity and increases abdominal aortic aneurysm development via Cox-2 activation. ( 29408196 )
2018
27
In vitro measurement of the permeability of endovascular coils deployed in cerebral aneurysms. ( 29298858 )
2018
28
Ten-year experience of the thoraco-abdominal aortic aneurysm treatment using a hybrid thoracic endovascular aortic repair. ( 29415193 )
2018
29
Case report of an unusual combination of purulent pericarditis and false aneurysm of the ascending aorta. ( 29378612 )
2018
30
Increased risk of malignancy in patients with an aortic aneurysm: a nationwide population-based retrospective study. ( 29416815 )
2018
31
Coronary artery aneurysm regression after Kawasaki disease and associated risk factors: a 3-year follow-up study in East China. ( 29330741 )
2018
32
Self-apposing stent-assisted coil embolization for the treatment of coronary artery aneurysm. ( 28988417 )
2018
33
Giant coronary aneurysm culprit of an acute coronary syndrome. ( 29317116 )
2018
34
Right Subclavian Artery Aneurysms with Fibromuscular Dysplasia. ( 29421412 )
2018
35
Evaluation of Application Value of Transcranial Doppler (TCD) in the Inspection of Cerebral Vasospasm After the Treatment of Intracranial Aneurysm. ( 29399014 )
2018
36
Thromboembolic complications during endovascular treatment of ruptured cerebral aneurysms. ( 29125027 )
2018
37
Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm. ( 29432192 )
2018
38
Exome Sequencing Identifies LOXL2 Mutation as a Cause of Familial Intracranial Aneurysm. ( 29107163 )
2018
39
Is fetal-type posterior cerebral artery a risk factor for intracranial aneurysm as analyzed by multislice CT angiography? ( 29434687 )
2018
40
Treatment of a wide-neck bifurcation aneurysm using a "WEB device waffle-cone technique". Technical note and case report. ( 29452325 )
2018
41
Periosteal chondroma of the cuboid with secondary aneurysmal bone cyst in a setting of secondary hyperparathyroidism. ( 29413778 )
2018
42
A case of a rectal stricture related to ischemic proctitis following rupture of an aortic aneurysm. ( 29399616 )
2018
43
Hemodynamics in a giant intracranial aneurysm characterized by in vitro 4D flow MRI. ( 29300738 )
2018
44
Clip ligation for ruptured intracranial aneurysm in a child with Loeys-Dietz syndrome: case report. ( 29350591 )
2018
45
Effect of Local Coil Density on Blood Flow Stagnation in Densely Coiled Cerebral Aneurysms: A Computational Study Using a Cartesian Grid Method. ( 29383379 )
2018
46
Spinal cord injury in endovascular thoracoabdominal aortic aneurysm repair: prevalence, risk factors and preventive strategies. ( 29424186 )
2018
47
Differential mRNA expression of inflammasome genes NLRP1 and NLRP3 in abdominal aneurysmal and occlusive aortic disease. ( 29347884 )
2018
48
Spinal adhesive arachnoiditis following the rupture of an Adamkiewicz aneurysm: Literature review and a case illustration. ( 29433818 )
2018
49
Snorkel Technique for Inferior Mesenteric Artery During Endovascular Repair of Abdominal Aortic Aneurysm. ( 29433410 )
2018
50
Association of plasma D-dimer level with thromboembolic events after endovascular coil treatment of ruptured cerebral aneurysms. ( 29424648 )
2018

Variations for Aneurysm

Expression for Aneurysm

Search GEO for disease gene expression data for Aneurysm.

Pathways for Aneurysm

Pathways related to Aneurysm according to GeneCards Suite gene sharing:

(show all 38)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.79 ACTA2 EFEMP2 ELN MYH11 MYLK SMAD3
2
Show member pathways
13.26 ACTA2 MYH11 MYLK SMAD3 TGFB2 TGFBR1
3
Show member pathways
13.14 ACTA2 EFEMP2 ELN MMP12 MYLK TGFB2
4
Show member pathways
12.88 ACTA2 MYH11 PRKG1 TGFB2 TGFBR1 TGFBR2
5
Show member pathways
12.67 EFEMP2 ELN LOX MFAP5 MMP12 TGFB2
6
Show member pathways
12.47 SMAD3 TGFB2 TGFBR1 TGFBR2
7
Show member pathways
12.42 SMAD3 TGFB2 TGFBR1 TGFBR2
8 12.37 SMAD3 TGFB2 TGFBR1 TGFBR2
9
Show member pathways
12.18 SMAD3 TGFB2 TGFBR1 TGFBR2
10 12.13 SMAD3 TGFB2 TGFBR1 TGFBR2
11
Show member pathways
12.13 ACTA2 EFEMP2 ELN MMP12 MYH11 MYLK
12 12.1 SMAD3 TGFB2 TGFBR1 TGFBR2
13
Show member pathways
12.09 SMAD3 TGFB2 TGFBR1 TGFBR2
14
Show member pathways
12.04 SMAD3 TGFB2 TGFBR1 TGFBR2
15 12.03 ACTA2 MYLK SMAD3 TGFBR1
16 12.01 MMP12 SMAD3 TGFBR1 TGFBR2
17 11.82 SMAD3 TGFB2 TGFBR1 TGFBR2
18
Show member pathways
11.81 SMAD3 TGFBR1 TGFBR2
19 11.78 SMAD3 TGFB2 TGFBR1 TGFBR2
20 11.77 MMP12 SMAD3 TGFB2 TGFBR1 TGFBR2
21
Show member pathways
11.74 SMAD3 TGFB2 TGFBR1 TGFBR2
22 11.74 ACTA2 SMAD3 TGFB2 TGFBR1 TGFBR2
23 11.69 SMAD3 TGFBR1 TGFBR2
24 11.69 SMAD3 TGFBR1 TGFBR2
25
Show member pathways
11.67 SMAD3 TGFBR1 TGFBR2
26 11.66 SMAD3 TGFB2 TGFBR1 TGFBR2
27 11.58 SMAD3 TGFBR1 TGFBR2
28
Show member pathways
11.56 SMAD3 TGFB2 TGFBR1 TGFBR2
29
Show member pathways
11.56 LOX SMAD3 TGFBR1 TGFBR2
30 11.52 SMAD3 TGFBR1 TGFBR2
31 11.49 TGFB2 TGFBR1 TGFBR2
32 11.34 ACTA2 MYLK TGFB2 TGFBR1 TGFBR2
33 11.31 ACTA2 MYH11 MYLK
34 11.08 SMAD3 TGFBR1 TGFBR2
35 10.96 SMAD3 TGFBR1 TGFBR2
36
Show member pathways
10.88 EFEMP2 ELN LOX MFAP5 TGFB2
37 10.73 TGFB2 TGFBR1 TGFBR2
38 10.73 SMAD3 TGFB2 TGFBR1 TGFBR2

GO Terms for Aneurysm

Cellular components related to Aneurysm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transforming growth factor beta receptor complex GO:0070022 8.62 TGFBR1 TGFBR2

Biological processes related to Aneurysm according to GeneCards Suite gene sharing:

(show all 26)
# Name GO ID Score Top Affiliating Genes
1 heart development GO:0007507 9.86 LOX TGFB2 TGFBR1 TGFBR2
2 muscle contraction GO:0006936 9.79 ACTA2 MYH11 MYLK
3 palate development GO:0060021 9.75 TGFB2 TGFBR1 TGFBR2
4 negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 9.7 SMAD3 TGFBR1 TGFBR2
5 collagen fibril organization GO:0030199 9.69 LOX TGFB2 TGFBR1
6 transforming growth factor beta receptor signaling pathway GO:0007179 9.67 SMAD3 TGFB2 TGFBR1 TGFBR2
7 lens development in camera-type eye GO:0002088 9.65 FOXE3 TGFBR1 TGFBR2
8 embryonic cranial skeleton morphogenesis GO:0048701 9.63 SMAD3 TGFBR1 TGFBR2
9 smooth muscle contraction GO:0006939 9.62 MYH11 MYLK
10 transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 9.62 TGFBR1 TGFBR2
11 activin receptor signaling pathway GO:0032924 9.61 SMAD3 TGFBR1
12 ventricular trabecula myocardium morphogenesis GO:0003222 9.6 TGFB2 TGFBR1
13 positive regulation of SMAD protein import into nucleus GO:0060391 9.59 SMAD3 TGFBR1
14 cardiac epithelial to mesenchymal transition GO:0060317 9.58 TGFB2 TGFBR1
15 ventricular septum morphogenesis GO:0060412 9.58 TGFB2 TGFBR1 TGFBR2
16 atrioventricular valve morphogenesis GO:0003181 9.57 TGFB2 TGFBR2
17 positive regulation of epithelial to mesenchymal transition GO:0010718 9.56 SMAD3 TGFB2 TGFBR1 TGFBR2
18 response to cholesterol GO:0070723 9.55 TGFBR1 TGFBR2
19 membranous septum morphogenesis GO:0003149 9.54 TGFB2 TGFBR2
20 pathway-restricted SMAD protein phosphorylation GO:0060389 9.5 TGFB2 TGFBR1 TGFBR2
21 regulation of transforming growth factor beta2 production GO:0032909 9.49 SMAD3 TGFB2
22 endocardial cushion fusion GO:0003274 9.43 TGFB2 TGFBR2
23 elastic fiber assembly GO:0048251 9.33 EFEMP2 LOX MYH11
24 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation GO:1905007 9.13 TGFB2 TGFBR1 TGFBR2
25 wound healing GO:0042060 9.1 LOX MMP12 SMAD3 TGFB2 TGFBR1 TGFBR2
26 protein phosphorylation GO:0006468 10.03 MYLK PRKG1 TGFB2 TGFBR1 TGFBR2

Molecular functions related to Aneurysm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix structural constituent GO:0005201 9.43 EFEMP2 ELN MFAP5
2 transforming growth factor beta binding GO:0050431 9.4 TGFBR1 TGFBR2
3 signal transducer, downstream of receptor, with serine/threonine kinase activity GO:0004702 9.37 TGFBR1 TGFBR2
4 transmembrane receptor protein serine/threonine kinase activity GO:0004675 9.32 TGFBR1 TGFBR2
5 type II transforming growth factor beta receptor binding GO:0005114 9.16 TGFB2 TGFBR1
6 transforming growth factor beta-activated receptor activity GO:0005024 8.96 TGFBR1 TGFBR2
7 SMAD binding GO:0046332 8.8 SMAD3 TGFBR1 TGFBR2

Sources for Aneurysm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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