Aliases & Classifications for Aneurysm

MalaCards integrated aliases for Aneurysm:

Name: Aneurysm 51 29 52 69
Aneurysms 41

Summaries for Aneurysm

NINDS : 51 A cerebral aneurysm is a weak or thin spot on a blood vessel in the brain that balloons out and fills with blood.  An aneurysm can press on a nerve or surrounding tissue, and also leak or burst, which lets blood spill into surrounding tissues (called a hemorrhage). Cerebral aneurysms can occur at any age, although they are more common in adults than in children and are slightly more common in women than in men.  The signs and symptoms of an unruptured cerebral aneurysm will partly depend on its size and rate of growth. For example, a small, unchanging aneurysm will generally produce no symptoms, whereas a larger aneurysm that is steadily growing may produce symptoms such as headache, numbness, loss of feeling in the face or problems with the eyes. Immediately after an aneurysm ruptures, an individual may experience such symptoms as a sudden and unusually severe headache, nausea, vision impairment, vomiting, and loss of consciousness.

MalaCards based summary : Aneurysm, also known as aneurysms, is related to aortic aneurysm and abdominal aortic aneurysm, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Aneurysm is ACTA2 (Actin, Alpha 2, Smooth Muscle, Aorta), and among its related pathways/superpathways are PAK Pathway and Integrin Pathway. The drugs Atenolol and Valsartan have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and heart, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and cardiovascular system

MedlinePlus : 41 an aneurysm is a bulge or "ballooning" in the wall of an artery. arteries are blood vessels that carry oxygen-rich blood from the heart to other parts of the body. if an aneurysm grows large, it can burst and cause dangerous bleeding or even death. most aneurysms occur in the aorta, the main artery that runs from the heart through the chest and abdomen. aneurysms also can happen in arteries in the brain, heart and other parts of the body. if an aneurysm in the brain bursts, it causes a stroke. aneurysms can develop and become large before causing any symptoms. often doctors can stop aneurysms from bursting if they find and treat them early. they use imaging tests to find aneurysms. often aneurysms are found by chance during tests done for other reasons. medicines and surgery are the two main treatments for aneurysms. nih: national heart, lung, and blood institute

Wikipedia : 72 An aneurysm is a localized, blood-filled balloon-like bulge in the wall of a blood vessel. Aneurysms can... more...

Related Diseases for Aneurysm

Diseases related to Aneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 853)
id Related Disease Score Top Affiliating Genes
1 aortic aneurysm 12.5
2 abdominal aortic aneurysm 12.4
3 intracranial aneurysm 12.3
4 aneurysmal bone cysts 12.2
5 aortic aneurysm, familial thoracic 1 12.2
6 cerebral aneurysms 12.2
7 familial thoracic aortic aneurysm and dissection 12.1
8 coronary artery aneurysm 12.1
9 intracranial berry aneurysm 12.1
10 familial abdominal aortic aneurysm 12.1
11 vein of galen aneurysm 12.1
12 aneurysm of sinus of valsalva 12.0
13 angiopathy, hereditary, with nephropathy, aneurysms, and muscle cramps 12.0
14 aortic aneurysm, familial thoracic 4 12.0
15 aneurysm, intracranial berry, 2 11.9
16 aortic aneurysm, familial thoracic 10 11.9
17 heart aneurysm 11.9
18 aortic aneurysm, familial thoracic 7 11.9
19 aortic aneurysm, familial thoracic 6 11.9
20 aortic aneurysm, familial thoracic 11 11.9
21 aneurysm, intracranial berry, 5 11.9
22 coronary aneurysm 11.9
23 aortic aneurysm, familial thoracic 9 11.9
24 aneurysm, intracranial berry, 3 11.9
25 aneurysm, intracranial berry, 9 11.9
26 aneurysm, intracranial berry, 4 11.9
27 aneurysm, intracranial berry, 11 11.9
28 aneurysm, intracranial berry, 10 11.9
29 aneurysm, intracranial berry, 6 11.9
30 aneurysm, intracranial berry, 7 11.9
31 aneurysm, intracranial berry, 8 11.9
32 aortic aneurysm, familial thoracic 8 11.9
33 aneurysm, intracranial berry, 1 11.8
34 splenic artery aneurysm 11.8
35 atrial septal aneurysm 11.8
36 subclavian artery aneurysm 11.8
37 familial cerebral saccular aneurysm 11.8
38 thoracic aortic aneurysms and aortic dissections 11.8
39 aneurysm of interventricular septum 11.7
40 loeys-dietz syndrome 11.7
41 congenital coronary artery aneurysm 11.7
42 acta2-related thoracic aortic aneurysms and aortic dissections 11.6
43 myh11-related thoracic aortic aneurysms and aortic dissections 11.6
44 aortic aneurysm, familial thoracic 2 11.6
45 aortic aneurysm, familial abdominal, 4 11.6
46 berry aneurysm, cirrhosis, pulmonary emphysema, and cerebral calcification 11.6
47 fetal left ventricular aneurysm 11.6
48 marfan syndrome/loeys-dietz syndrome/familial thoracic aortic aneurysms and dissections 11.6
49 fbn1-related thoracic aortic aneurysms and aortic dissections 11.6
50 mfap5-related thoracic aortic aneurysms and aortic dissections 11.6

Graphical network of the top 20 diseases related to Aneurysm:



Diseases related to Aneurysm

Symptoms & Phenotypes for Aneurysm

UMLS symptoms related to Aneurysm:


angina pectoris, chest pain, edema

GenomeRNAi Phenotypes related to Aneurysm according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-104 9.72 TGFBR2
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-14 9.72 TGFB2
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-141 9.72 TGFB2
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-145 9.72 TGFBR2 PRKG1
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.72 TGFBR2
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-165 9.72 TGFBR1 TGFBR2
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.72 TGFBR1
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-20 9.72 TGFBR2
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.72 TGFBR1
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-216 9.72 PRKG1
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-26 9.72 TGFB2
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-48 9.72 TGFBR2
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-59 9.72 TGFB2
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-60 9.72 TGFBR2 PRKG1 TGFB2 TGFBR1
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-65 9.72 TGFBR2
16 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.72 TGFB2
17 Decreased shRNA abundance (Z-score < -2) GR00366-A-72 9.72 TGFB2
18 Decreased shRNA abundance (Z-score < -2) GR00366-A-75 9.72 PRKG1
19 Decreased shRNA abundance (Z-score < -2) GR00366-A-77 9.72 TGFBR1
20 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.72 TGFBR2

MGI Mouse Phenotypes related to Aneurysm:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.03 MYLK PRKG1 SMAD3 TGFB2 TGFBR1 ACTA2
2 digestive/alimentary MP:0005381 9.7 MYH11 MYLK PRKG1 SMAD3 TGFB2 TGFBR1
3 muscle MP:0005369 9.61 MYLK PRKG1 TGFB2 TGFBR1 ACTA2 EFEMP2
4 respiratory system MP:0005388 9.17 MYH11 TGFB2 TGFBR1 EFEMP2 TGFBR2 LOX

Drugs & Therapeutics for Aneurysm

Drugs for Aneurysm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 388)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Atenolol Approved Phase 4 29122-68-7 2249
2
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
3
Acetazolamide Approved, Vet_approved Phase 4,Phase 2 59-66-5 1986
4
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2 1197-18-8 5526
5
Everolimus Approved Phase 4,Phase 3,Phase 1,Phase 2 159351-69-6 6442177
6
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
7
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 53123-88-9 5284616 6436030 46835353
8
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
9
Ramipril Approved Phase 4 87333-19-5 5362129
10
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 2078-54-8 4943
11
Sevoflurane Approved, Vet_approved Phase 4,Phase 3,Phase 2 28523-86-6 5206
12
Benzocaine Approved Phase 4,Phase 1,Phase 2,Early Phase 1 1994-09-7, 94-09-7 2337
13
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 76631-46-4, 113775-47-6 68602 5311068 56032
14
Amlodipine Approved Phase 4,Phase 3,Phase 2 88150-42-9 2162
15
Clevidipine Approved Phase 4,Phase 2 167221-71-8
16
Telmisartan Approved, Investigational Phase 4 144701-48-4 65999
17
Remifentanil Approved Phase 4 132875-61-7 60815
18
Morphine Approved, Investigational Phase 4,Phase 3 57-27-2 5288826
19
Acetaminophen Approved Phase 4,Phase 3,Phase 2 103-90-2 1983
20
Bupivacaine Approved, Investigational Phase 4,Phase 1 2180-92-9, 38396-39-3 2474
21
Levobupivacaine Approved Phase 4 27262-47-1 92253
22
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
23
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-78-2 2244
24
Desflurane Approved Phase 4 57041-67-5 42113
25
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
26
Olmesartan Approved, Investigational Phase 4,Phase 3 144689-24-7, 144689-63-4 158781 130881
27
Mannitol Approved, Investigational Phase 4,Phase 1,Phase 2 69-65-8 453 6251
28
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
29
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
30
Eplerenone Approved Phase 4 107724-20-9 150310 443872
31
Spironolactone Approved Phase 4 1952-01-7, 52-01-7 5833
32 Piracetam Approved Phase 4 7491-74-9
33
Phenprocoumon Approved Phase 4 435-97-2 9908 54680692
34
Ranibizumab Approved Phase 4 347396-82-1 459903
35
Clopidogrel Approved, Nutraceutical Phase 4,Phase 3 120202-66-6, 113665-84-2 60606
36 tannic acid Approved, Nutraceutical Phase 4,Phase 1,Phase 2,Early Phase 1
37
Menadione Approved, Nutraceutical Phase 4,Phase 3 58-27-5 4055
38
Phytonadione Approved, Nutraceutical Phase 4,Phase 3 84-80-0 4812 5284607
39
Angiotensin II Investigational Phase 4,Phase 3 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
40
Iodine Investigational Phase 4 7553-56-2 807
41 Etiracetam Investigational Phase 4 33996-58-6
42 Adrenergic Agents Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1
43 Adrenergic Antagonists Phase 4,Phase 3,Phase 1,Early Phase 1
44 Adrenergic beta-1 Receptor Antagonists Phase 4,Phase 3,Early Phase 1
45 Adrenergic beta-Antagonists Phase 4,Phase 3,Early Phase 1
46 Angiotensin II Type 1 Receptor Blockers Phase 4,Phase 3
47 Angiotensin Receptor Antagonists Phase 4,Phase 3
48 Angiotensinogen Phase 4,Phase 3
49 Anti-Arrhythmia Agents Phase 4,Phase 3
50 Antihypertensive Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 926)

id Name Status NCT ID Phase Drugs
1 Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization Unknown status NCT01029938 Phase 4
2 Prophylactic Mesh Implantation After Abdominal Aortic Aneurysm Repair Unknown status NCT01353443 Phase 4
3 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4 herbal drug;placebo
4 Comparison of Beta-blocker Versus Angiotensin Receptor Blocker for Suppression of Aneurysm Expansion in Patients With Small Abdominal Aortic Aneurysm and Hypertension (BASE Trial) Unknown status NCT01904981 Phase 4 Beta-blocker-Atenolol 50mg, PO(peroral), Once daily;Angiotensin receptor blocker-Valsartan 80mg, PO(peroral), Once daily
5 Immunonutrition and Thoracoabdominal Aorta Aneurysm Repair Unknown status NCT00339053 Phase 4 Immunonutrition ( Impact)
6 Effectiveness of Acetazolamide in Reducing Paralysis of the Leg in Patients Undergoing Aortic Aneurysm Surgery Surgery Unknown status NCT01889498 Phase 4 Acetazolamide
7 HYdrogel Coil Versus Bare Platinum Coil in Recanalization Imaging Data Study Unknown status NCT01516658 Phase 4
8 Arterial Catheter to Monitor Glycemia Unknown status NCT01176279 Phase 4
9 Tranexamic Acid in Major Vascular Surgery Unknown status NCT02335359 Phase 4 tranexamic acid diluted in 100 ml of saline solution (loading dose);tranexamic acid undiluted (continous infusion);Placebo
10 Efficacy of Xience/Promus Versus Cypher in rEducing Late Loss After stENTing Unknown status NCT00698607 Phase 4 6-month clopidogrel therapy;12-month clopidogrel therapy
11 Prospective, Multicenter Study of the Second Generation Antimicrobial Graft in the Abdominal Position Unknown status NCT00824109 Phase 4
12 Statin and Angiotensin-converting Enzyme Inhibitor on Symptoms in Patients With SCAD Unknown status NCT02008786 Phase 4 ramipril;rosuvastatin;placebo
13 A Morbidity-Mortality and Remodeling Study With Valsartan Unknown status NCT00133328 Phase 4 valsartan
14 Aneurysm Wall Histology Registry Completed NCT01444664 Phase 4
15 MAPS Trial: Matrix And Platinum Science Completed NCT00396981 Phase 4
16 Post-Approval Trial of the Talent™ Abdominal Stent Graft to Treat Aortic Aneurysms Completed NCT00816062 Phase 4
17 Endovascular Repair of Descending Thoracic Aortic Aneurysms Completed NCT00802984 Phase 4
18 Endovascular Repair of Abdominal Aortic Aneurysms Completed NCT00803075 Phase 4
19 GORE EXCLUDER® Endoprosthesis - Low Permeability in Treatment of Abdominal Aortic Aneurysms Completed NCT00593814 Phase 4
20 Standard Open Surgery Versus Endovascular Repair of Abdominal Aortic Aneurysm (AAA) Completed NCT00094575 Phase 4
21 Study of the Effectiveness of Telmisartan in Slowing the Progression of Abdominal Aortic Aneurysms Completed NCT01683084 Phase 4 Telmisartan;Placebo
22 TRAIL: Treatment of Intracranial Aneurysms With LVIS® System Completed NCT02921711 Phase 4
23 Statin Use in Abdominal Aortic Aneurysm Repair Completed NCT01062802 Phase 4 Atorvastatin
24 Opioid-potentiated Volative Anaesthetic Vs. Remifentanil And Propofol During Abdominal Aortic Aneurysm Surgery Completed NCT00538421 Phase 4 Propofol;Sevoflurane
25 Role of Propofol Postconditioning on Oxidative Stress and Cognitive Function Completed NCT02691416 Phase 4 propofol postconditioning;sevoflurane
26 Fibrinogen as an Alternative to FFP in Aortic Surgery. Completed NCT00994045 Phase 4
27 PRET: Patients Prone to Recurrence After Endovascular Treatment Completed NCT00626912 Phase 4
28 The Registry to Study Safety and Performance of the CORDIS Vascular Reconstruction Device and Delivery System Completed NCT00486226 Phase 4
29 Effects of a Surgery-induced Peripheral Inflammatory Response on the Blood Brain Barrier Completed NCT00878371 Phase 4 morphine
30 Prevalence of Abdominal Aortic Aneurysm in Patients Undergoing Coronary Angiography Completed NCT01239225 Phase 4
31 Epidural Versus Wound Infusion Plus Morphine Bolus in Open Abdominal Aortic Aneurysm Repair Completed NCT02677532 Phase 4 Paracetamol;Levobupivacaine wound infiltration;Levobupivacaine epidural bolus;Sufentanil epidural bolus;Morphine;Levobupivacaine plus sufentanil epidural infusion;Levobupivacaine wound infusion
32 The Pharmacokinetics of Opioids and Sedative/Hypnotics During Selective Cerebral Perfusion Completed NCT00494598 Phase 4 Sufentanil
33 Thoracoabdominal Arortic CTA Study Completed NCT02291718 Phase 4 Isovue
34 A Better Choice for Patients Undergoing Endovascular Coil Embolization Completed NCT01722409 Phase 4 sevoflurane and 0.5 μg/kg dexmedetomidine;sevoflurane and 1 μg/kg dexmedetomidine
35 Trial to Assess the Efficacy of Combination Formula of Aspirin Plus Clopidogrel in Patients With Coronary Stent Completed NCT02410083 Phase 4 Clopirin 1;Clopidogrel-Aspirin(co-administration) 1;Clopirin 2;Clopidogrel-Aspirin(co-administration) 2
36 Vasculopathic Injury and Plasma as Endothelial Rescue - OCTAplas Trial (EudraCT no. 2014-000452-28) Completed NCT02253082 Phase 4 OctaplasLG®
37 Atorvastatin in Perioperative Vascular Surgery - Pilot Study Completed NCT00610545 Phase 4 Atorvastatin;Atorvastatin
38 A Controlled Trial of Effectiveness of a Backward Walking Program in Patients Recovering From Abdominal Aorta Surgery Completed NCT00819936 Phase 4
39 Comparison of Neuroprotection by Propofol and Desflurane for POCD Following Subarachnoid Hemorrhage Surgery Completed NCT02987218 Phase 4 Propofol;Desflurane
40 Randomized Trial of Pulsatile vs Non Pulsatile Perfusion on Short Term Changes in Kidney Function Using an Intra-Aortic Ballooon Pump During Cardioplegic Arrest in Patients Undergoing Myocardial Reperfusion Completed NCT00454428 Phase 4
41 Study of Pain, Anxiety and Complications Related to Cannulation of Arteriovenous (AV) Fistula in Chronic Hemodialysis Patients Completed NCT00544492 Phase 4
42 XIENCE V: SPIRIT WOMEN Sub-study Completed NCT01182428 Phase 4
43 Add-on Effects of Valsartan on Morbi- Mortality (KYOTO HEART Study) Completed NCT00149227 Phase 4 Valsartan;Non-ARB
44 OlmeSartan and Calcium Antagonists Randomized (OSCAR) Study Completed NCT00134160 Phase 4 Olmesartan medoxomil;Calcium channel blockers (amlodipine, azelnidipine)
45 Stenting in the Treatment of Aneurysm Trial Recruiting NCT01340612 Phase 4
46 TARGET Intracranial Aneurysm Coiling Registry Recruiting NCT01748903 Phase 4
47 LARGE Aneurysm Randomized Trial: Flow Diversion Versus Traditional Endovascular Coiling Therapy Recruiting NCT01762137 Phase 4
48 Eplerenone in the Management of Abdominal Aortic Aneurysms Recruiting NCT02345590 Phase 4 Eplerenone
49 Seizure Prophylaxis in Aneurysm Repair Recruiting NCT01801072 Phase 4 Levetiracetam
50 Flow Diversion in Intracranial Aneurysm Treatment Recruiting NCT01349582 Phase 4

Search NIH Clinical Center for Aneurysm

Genetic Tests for Aneurysm

Genetic tests related to Aneurysm:

id Genetic test Affiliating Genes
1 Aneurysm 29

Anatomical Context for Aneurysm

MalaCards organs/tissues related to Aneurysm:

39
Bone, Brain, Heart, Kidney, Spinal Cord, Testes, Endothelial

Publications for Aneurysm

Articles related to Aneurysm:

(show top 50) (show all 8707)
id Title Authors Year
1
Surgical repair of a pseudocoarctation with cervical aortic arch complicated by multiple aneurysms of the aorta: a case report. ( 28690750 )
2017
2
Management of a complicated redo giant dissecting aortic aneurysm. ( 28906534 )
2017
3
A failure of preoperative duplex imaging to diagnose a lower extremity venous aneurysm in a patient with severe chronic venous insufficiency. ( 28255445 )
2017
4
Predicting the Need for Intra-operative Large Volume Blood Transfusions During Thoraco-abdominal Aortic Aneurysm Repair. ( 28089084 )
2017
5
Influence of Relative Residence Time on Side-Wall Aneurysm Inception. ( 28945849 )
2017
6
Bile-ated Cell Death Decreases Aortic Aneurysm Formation. ( 28089083 )
2017
7
Giant left circumflex coronary artery aneurysm with fistula to the right atrium. ( 28745134 )
2017
8
Transapical aortic perfusion using a deep hypothermic procedure to prevent dissecting lung injury during re-do thoracoabdominal aortic aneurysm surgery. ( 28526092 )
2017
9
Ascending aortic pseudo-aneurysm treated with 'coil and plug'. ( 28950328 )
2017
10
Comparison of the Prevalence of Ruptured and Unruptured Cerebral Aneurysms in a Poor Urban Minority Population. ( 28623116 )
2017
11
Size is the Most Important Predictor of Aneurysm Rupture Among Multiple Cerebral Aneurysms: Post Hoc Subgroup Analysis of Unruptured Cerebral Aneurysm Study Japan. ( 28637201 )
2017
12
Diagnostic value of 3D time-of-flight magnetic resonance angiography for detecting intracranial aneurysm: a meta-analysis. ( 28887618 )
2017
13
Massive aortic root aneurysm in an infant with the Loeys-Dietz syndrome. ( 28606209 )
2017
14
Endovascular Repair of a Splenic Artery Aneurysm With Anomalous Origin From the Superior Mesenteric Artery. ( 28330438 )
2017
15
Intravascular Treatment of Left Subclavian Artery Aneurysm Coexisting with Aortic Coarctation in an Adult Patient. ( 28401193 )
2017
16
Small versus Large Ruptured Intracranial Aneurysm: Concerns with the Site of Aneurysm. ( 28088803 )
2017
17
Resolution of giant basilar artery aneurysm compression and reversal of sensorineural hearing loss with use of a flow diverter: case report. ( 28452658 )
2017
18
Unusual presentation of silently growing abdominal aortic aneurysm causing biliary obstruction. ( 28947424 )
2017
19
Prevalence of Intracranial Aneurysm in Women With Fibromuscular Dysplasia: A Report From the US Registry for Fibromuscular Dysplasia. ( 28715558 )
2017
20
Circumferential Wall Enhancement on Magnetic Resonance Imaging is Useful to Identify Rupture Site in Patients with Multiple Cerebral Aneurysms. ( 28586440 )
2017
21
Hybrid Management of a Giant Left Main Coronary Artery Aneurysm. ( 28007286 )
2017
22
A Rare Presentation of Abdominal Aortic Aneurysm-Renal Pelvis Rupture Due to Compression. ( 28887257 )
2017
23
Lifestyle and Risk of Screening-Detected Abdominal Aortic Aneurysm in Men. ( 28490522 )
2017
24
Double-lumen atherosclerotic abdominal aortic aneurysm. ( 28010862 )
2017
25
Difficult diagnosis of Kawasaki disease in a patient with giant coronary artery aneurysms. ( 28895991 )
2017
26
Big thrombus "sitting" in an atrial septal aneurysm. ( 28560753 )
2017
27
Rates of Spinal Cord Infarction After Repair of Aortic Aneurysm or Dissection. ( 28655811 )
2017
28
MiR-29b Downregulation Induces Phenotypic Modulation of Vascular Smooth Muscle Cells: Implication for Intracranial Aneurysm Formation and Progression to Rupture. ( 28214880 )
2017
29
Rationale for graft selection in patients with complex internal carotid artery aneurysms treated with extracranial to intracranial high-flow bypass and therapeutic internal carotid artery occlusion. ( 28574313 )
2017
30
Reoperation rates after open and endovascular abdominal aortic aneurysm repairs. ( 28073669 )
2017
31
Upregulation of MicroRNA-15a Contributes to Pathogenesis of Abdominal Aortic Aneurysm (AAA) by Modulating the Expression of Cyclin-Dependent Kinase Inhibitor 2B (CDKN2B). ( 28214350 )
2017
32
Transcatheter closure of a giant right subclavian artery aneurysm. ( 28130597 )
2017
33
Coronary Aneurysm Formation After Bioresorbable Vascular Scaffold Implantation Resulting in Acute Myocardial Infarction. ( 28512285 )
2017
34
Intraprocedural Rupture of Unruptured Cerebral Aneurysms During Coil Embolization: A Single-Center Experience. ( 28583450 )
2017
35
3D Printing of Preoperative Simulation Models of a Splenic Artery Aneurysm: Precision and Accuracy. ( 28130050 )
2017
36
Effects of acute exercise on endothelial function in abdominal aortic aneurysm patients. ( 28939648 )
2017
37
Coronary artery aneurysm formation following implantation of a bioresorbable vascular scaffold for in-stent restenosis. ( 28579092 )
2017
38
Reversible cerebral vasoconstriction syndrome: an important non-aneurysmal cause of thunderclap headaches and subarachnoid hemorrhage. ( 28779450 )
2017
39
Successful Hybrid Neurovascular Surgery for a Ruptured Basilar Artery Dissecting Aneurysm in a Patient with Jeopardized Collateral Circulation Associated with Aortitis Syndrome. ( 28602923 )
2017
40
Comparison of Endovascular Stent Grafts for Abdominal Aortic Aneurysm Repair in Medicare Beneficiaries. ( 28890065 )
2017
41
Fatal Mycotic Aneurysm of the Basilar Artery Caused by Aspergillus fumigatus in a Patient with Pituitary Adenoma and Meningitis. ( 28770205 )
2017
42
Loss-of-function mutations in the X-linked biglycan gene cause a severe syndromic form of thoracic aortic aneurysms and dissections. ( 27632686 )
2017
43
Translational Relevance and Recent Advances of Animal Models of Abdominal Aortic Aneurysm. ( 28062500 )
2017
44
The therapeutic challenge of giant splenic artery aneurysm: a case repport. ( 28746591 )
2017
45
Definitive Endovascular Repair of a Brucellar Descending Thoracic Aortic Aneurysm. ( 28513124 )
2017
46
Using multiple classifiers for predicting the risk of endovascular aortic aneurysm repair re-intervention through hybrid feature selection. ( 28925817 )
2017
47
Nicotinamide Phosphoribosyltransferase in Smooth Muscle Cells Maintains Genome Integrity, Resists Aortic Medial Degeneration, and Is Suppressed in Human Thoracic Aortic Aneurysm Disease. ( 28356339 )
2017
48
Higher 30 Day Mortality in Patients with Familial Abdominal Aortic Aneurysm after EVAR. ( 28579278 )
2017
49
Clinical outcomes and a high prevalence of abnormalities on comprehensive arterial and venous thrombophilia screening in TIA or ischaemic stroke patients with a patent foramen ovale, an inter-atrial septal aneurysm or both. ( 28477701 )
2017
50
Aortic Aneurysm-associated Disseminated Intravascular Coagulation (DIC) that Responded Well to a Switch from Warfarin to Rivaroxaban. ( 28943552 )
2017

Variations for Aneurysm

Expression for Aneurysm

Search GEO for disease gene expression data for Aneurysm.

Pathways for Aneurysm

Pathways related to Aneurysm according to GeneCards Suite gene sharing:

(show all 32)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.25 ACTA2 MYH11 MYLK SMAD3 TGFB2 TGFBR1
2
Show member pathways
13.25 ACTA2 EFEMP2 ELN MMP12 MYH11 MYLK
3
Show member pathways
12.85 ACTA2 MYH11 PRKG1 TGFB2 TGFBR1 TGFBR2
4
Show member pathways
12.79 ACTA2 MYLK TGFB2 TGFBR1 TGFBR2
5
Show member pathways
12.66 EFEMP2 ELN LOX MFAP5 MMP12 TGFB2
6
Show member pathways
12.4 SMAD3 TGFB2 TGFBR1 TGFBR2
7 12.35 SMAD3 TGFB2 TGFBR1 TGFBR2
8
Show member pathways
12.16 SMAD3 TGFB2 TGFBR1 TGFBR2
9 12.07 SMAD3 TGFB2 TGFBR1 TGFBR2
10
Show member pathways
12.02 SMAD3 TGFB2 TGFBR1 TGFBR2
11 12.01 ACTA2 MYLK SMAD3 TGFBR1
12 11.98 MMP12 SMAD3 TGFBR1 TGFBR2
13 11.81 SMAD3 TGFB2 TGFBR1 TGFBR2
14
Show member pathways
11.79 SMAD3 TGFBR1 TGFBR2
15 11.78 SMAD3 TGFB2 TGFBR1 TGFBR2
16 11.77 MMP12 SMAD3 TGFB2 TGFBR1 TGFBR2
17
Show member pathways
11.74 SMAD3 TGFB2 TGFBR1 TGFBR2
18 11.74 ACTA2 SMAD3 TGFB2 TGFBR1 TGFBR2
19 11.67 SMAD3 TGFBR1 TGFBR2
20 11.66 SMAD3 TGFBR1 TGFBR2
21
Show member pathways
11.64 SMAD3 TGFBR1 TGFBR2
22 11.59 SMAD3 TGFB2 TGFBR1 TGFBR2
23 11.56 SMAD3 TGFBR1 TGFBR2
24
Show member pathways
11.53 SMAD3 TGFB2 TGFBR1 TGFBR2
25 11.49 SMAD3 TGFBR1 TGFBR2
26 11.46 TGFB2 TGFBR1 TGFBR2
27 11.28 ACTA2 MYH11 MYLK
28 11.07 SMAD3 TGFBR1 TGFBR2
29 10.9 SMAD3 TGFBR1 TGFBR2
30
Show member pathways
10.88 EFEMP2 ELN LOX MFAP5 TGFB2
31 10.82 TGFB2 TGFBR1 TGFBR2
32 10.73 SMAD3 TGFB2 TGFBR1 TGFBR2

GO Terms for Aneurysm

Cellular components related to Aneurysm according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transforming growth factor beta receptor complex GO:0070022 8.62 TGFBR1 TGFBR2

Biological processes related to Aneurysm according to GeneCards Suite gene sharing:

(show all 25)
id Name GO ID Score Top Affiliating Genes
1 heart development GO:0007507 9.87 LOX TGFB2 TGFBR1 TGFBR2
2 muscle contraction GO:0006936 9.79 ACTA2 MYH11 MYLK
3 palate development GO:0060021 9.76 TGFB2 TGFBR1 TGFBR2
4 negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 9.71 SMAD3 TGFBR1 TGFBR2
5 signal transduction by protein phosphorylation GO:0023014 9.69 TGFB2 TGFBR1 TGFBR2
6 collagen fibril organization GO:0030199 9.67 LOX TGFB2 TGFBR1
7 lens development in camera-type eye GO:0002088 9.63 FOXE3 TGFBR1 TGFBR2
8 smooth muscle contraction GO:0006939 9.62 MYH11 MYLK
9 transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 9.62 TGFBR1 TGFBR2
10 transforming growth factor beta receptor signaling pathway GO:0007179 9.62 SMAD3 TGFB2 TGFBR1 TGFBR2
11 activin receptor signaling pathway GO:0032924 9.61 SMAD3 TGFBR1
12 embryonic cranial skeleton morphogenesis GO:0048701 9.61 SMAD3 TGFBR1 TGFBR2
13 ventricular trabecula myocardium morphogenesis GO:0003222 9.6 TGFB2 TGFBR1
14 cardiac epithelial to mesenchymal transition GO:0060317 9.59 TGFB2 TGFBR1
15 atrioventricular valve morphogenesis GO:0003181 9.58 TGFB2 TGFBR2
16 ventricular septum morphogenesis GO:0060412 9.58 TGFB2 TGFBR1 TGFBR2
17 response to cholesterol GO:0070723 9.56 TGFBR1 TGFBR2
18 membranous septum morphogenesis GO:0003149 9.55 TGFB2 TGFBR2
19 elastic fiber assembly GO:0048251 9.52 LOX MYH11
20 regulation of transforming growth factor beta2 production GO:0032909 9.48 SMAD3 TGFB2
21 positive regulation of epithelial to mesenchymal transition GO:0010718 9.46 SMAD3 TGFB2 TGFBR1 TGFBR2
22 pathway-restricted SMAD protein phosphorylation GO:0060389 9.43 TGFB2 TGFBR1 TGFBR2
23 endocardial cushion fusion GO:0003274 9.37 TGFB2 TGFBR2
24 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation GO:1905007 9.13 TGFB2 TGFBR1 TGFBR2
25 wound healing GO:0042060 9.1 LOX MMP12 SMAD3 TGFB2 TGFBR1 TGFBR2

Molecular functions related to Aneurysm according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular matrix structural constituent GO:0005201 9.5 EFEMP2 ELN MFAP5
2 transforming growth factor beta binding GO:0050431 9.4 TGFBR1 TGFBR2
3 transmembrane receptor protein serine/threonine kinase activity GO:0004675 9.37 TGFBR1 TGFBR2
4 type II transforming growth factor beta receptor binding GO:0005114 9.26 TGFB2 TGFBR1
5 transforming growth factor beta-activated receptor activity GO:0005024 9.16 TGFBR1 TGFBR2
6 SMAD binding GO:0046332 9.13 SMAD3 TGFBR1 TGFBR2
7 signal transducer, downstream of receptor, with serine/threonine kinase activity GO:0004702 8.8 TGFB2 TGFBR1 TGFBR2

Sources for Aneurysm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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