Aliases & Classifications for Aneurysm

Aliases & Descriptions for Aneurysm:

Name: Aneurysm 51 29 52 69
Aneurysms 41

Summaries for Aneurysm

NINDS : 51 A cerebral aneurysm is a weak or thin spot on a blood vessel in the brain that balloons out and fills with blood.  An aneurysm can press on a nerve or surrounding tissue, and also leak or burst, which lets blood spill into surrounding tissues (called a hemorrhage). Cerebral aneurysms can occur at any age, although they are more common in adults than in children and are slightly more common in women than in men.  The signs and symptoms of an unruptured cerebral aneurysm will partly depend on its size and rate of growth. For example, a small, unchanging aneurysm will generally produce no symptoms, whereas a larger aneurysm that is steadily growing may produce symptoms such as headache, numbness, loss of feeling in the face or problems with the eyes. Immediately after an aneurysm ruptures, an individual may experience such symptoms as a sudden and unusually severe headache, nausea, vision impairment, vomiting, and loss of consciousness.

MalaCards based summary : Aneurysm, also known as aneurysms, is related to mass syndrome and renal oncocytoma, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Aneurysm is ACTA2 (Actin, Alpha 2, Smooth Muscle, Aorta), and among its related pathways/superpathways are Integrin Pathway and Collagen chain trimerization. The drugs Aspirin and Ramipril have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and heart, and related phenotypes are cardiovascular system and integument

MedlinePlus : 41 an aneurysm is a bulge or "ballooning" in the wall of an artery. arteries are blood vessels that carry oxygen-rich blood from the heart to other parts of the body. if an aneurysm grows large, it can burst and cause dangerous bleeding or even death. most aneurysms occur in the aorta, the main artery that runs from the heart through the chest and abdomen. aneurysms also can happen in arteries in the brain, heart and other parts of the body. if an aneurysm in the brain bursts, it causes a stroke. aneurysms can develop and become large before causing any symptoms. often doctors can stop aneurysms from bursting if they find and treat them early. they use imaging tests to find aneurysms. often aneurysms are found by chance during tests done for other reasons. medicines and surgery are the two main treatments for aneurysms. nih: national heart, lung, and blood institute

Wikipedia : 71 An aneurysm is a localized, blood-filled balloon-like bulge in the wall of a blood vessel. Aneurysms can... more...

Related Diseases for Aneurysm

Diseases related to Aneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 854)
id Related Disease Score Top Affiliating Genes
1 mass syndrome 31.0 ACTA2 ELN FBN1 TGFBR1 TGFBR2
2 renal oncocytoma 29.3 ELN MMP12 MMP9
3 cavernous malformation 25.8 AAT1 ACTA2 ANIB1 ANIB2 ANIB3 ANIB4
4 aortic aneurysm 12.5
5 abdominal aortic aneurysm 12.4
6 intracranial aneurysm 12.3
7 thoracic aortic aneurysm 12.3
8 cerebral aneurysms 12.2
9 aneurysmal bone cysts 12.2
10 familial thoracic aortic aneurysm and dissection 12.1
11 coronary artery aneurysm 12.1
12 aortic aneurysm, familial thoracic 1 12.1
13 intracranial berry aneurysm 12.1
14 vein of galen aneurysm 12.1
15 familial abdominal aortic aneurysm 12.0
16 angiopathy, hereditary, with nephropathy, aneurysms, and muscle cramps 12.0
17 aneurysm of sinus of valsalva 12.0
18 aortic aneurysm, familial thoracic 4 12.0
19 aneurysm, intracranial berry, 2 12.0
20 heart aneurysm 11.9
21 aortic aneurysm, familial thoracic 7 11.9
22 aortic aneurysm, familial thoracic 6 11.9
23 aortic aneurysm, familial thoracic 10 11.9
24 coronary aneurysm 11.9
25 aortic aneurysm, familial thoracic 9 11.9
26 aneurysm, intracranial berry, 1 11.9
27 aortic aneurysm, familial thoracic 11 11.9
28 aneurysm, intracranial berry, 5 11.9
29 aortic aneurysm, familial thoracic 8 11.9
30 aneurysm, intracranial berry, 11 11.9
31 aneurysm, intracranial berry, 7 11.9
32 aneurysm, intracranial berry, 10 11.9
33 aneurysm, intracranial berry, 4 11.9
34 aneurysm, intracranial berry, 6 11.9
35 aneurysm, intracranial berry, 9 11.9
36 aneurysm, intracranial berry, 8 11.9
37 aneurysm, intracranial berry, 3 11.9
38 splenic artery aneurysm 11.8
39 atrial septal aneurysm 11.8
40 subclavian artery aneurysm 11.8
41 familial cerebral saccular aneurysm 11.8
42 thoracic aortic aneurysms and aortic dissections 11.8
43 loeys-dietz syndrome 11.8
44 aneurysm of interventricular septum 11.7
45 congenital coronary artery aneurysm 11.7
46 acta2-related thoracic aortic aneurysms and aortic dissections 11.7
47 myh11-related thoracic aortic aneurysms and aortic dissections 11.7
48 prkg1-related thoracic aortic aneurysms and aortic dissections 11.6
49 berry aneurysm, cirrhosis, pulmonary emphysema, and cerebral calcification 11.6
50 mfap5-related thoracic aortic aneurysms and aortic dissections 11.6

Graphical network of the top 20 diseases related to Aneurysm:



Diseases related to Aneurysm

Symptoms & Phenotypes for Aneurysm

UMLS symptoms related to Aneurysm:


angina pectoris, chest pain, edema

MGI Mouse Phenotypes related to Aneurysm:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.07 MMP13 MMP9 MYH11 ACTA2 MYLK COL3A1
2 integument MP:0010771 9.76 MMP12 MMP13 MMP9 MYH11 COL3A1 TGFBR1
3 muscle MP:0005369 9.65 MMP9 MYH11 ACTA2 MYLK COL3A1 TGFBR1
4 respiratory system MP:0005388 9.23 MMP12 MMP9 MYH11 COL3A1 TGFBR1 FBN1

Drugs & Therapeutics for Aneurysm

Drugs for Aneurysm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 385)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-78-2 2244
2
Ramipril Approved Phase 4 87333-19-5 5362129
3
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
4
Amlodipine Approved Phase 4,Phase 3,Phase 2 88150-42-9 2162
5
Atenolol Approved Phase 4 29122-68-7 2249
6
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
7
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 76631-46-4, 113775-47-6 68602 5311068 56032
8
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
9
Sevoflurane Approved, Vet_approved Phase 4,Phase 3,Phase 2 28523-86-6 5206
10
Acetazolamide Approved, Vet_approved Phase 4,Phase 2 59-66-5 1986
11
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2 1197-18-8 5526
12
Everolimus Approved Phase 4,Phase 3,Phase 1,Phase 2 159351-69-6 6442177
13
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 2078-54-8 4943
14
Benzocaine Approved Phase 4,Phase 1,Phase 2,Early Phase 1 1994-09-7, 94-09-7 2337
15
Clevidipine Approved Phase 4,Phase 2 167221-71-8
16
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 53123-88-9 5284616 6436030 46835353
17
Mannitol Approved, Investigational Phase 4,Phase 1,Phase 2 69-65-8 453 6251
18
Morphine Approved, Investigational Phase 4,Phase 3 57-27-2 5288826
19
Acetaminophen Approved Phase 4,Phase 3,Phase 2 103-90-2 1983
20
Olmesartan Approved, Investigational Phase 4,Phase 3 144689-24-7, 144689-63-4 158781 130881
21
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
22
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
23
Remifentanil Approved Phase 4 132875-61-7 60815
24
Bupivacaine Approved, Investigational Phase 4,Phase 1 2180-92-9, 38396-39-3 2474
25
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
26
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
27
Desflurane Approved Phase 4 57041-67-5 42113
28
Levobupivacaine Approved Phase 4 27262-47-1 92253
29
Coal tar Approved Phase 4 8007-45-2
30
Spironolactone Approved Phase 4 1952-01-7, 52-01-7 5833
31
Eplerenone Approved Phase 4 107724-20-9 150310 443872
32 Piracetam Approved Phase 4 7491-74-9
33
Phenprocoumon Approved Phase 4 435-97-2 9908 54680692
34
Telmisartan Approved, Investigational Phase 4 144701-48-4 65999
35
Clopidogrel Approved, Nutraceutical Phase 4,Phase 3 120202-66-6, 113665-84-2 60606
36 tannic acid Approved, Nutraceutical Phase 4,Phase 1,Phase 2,Early Phase 1
37
Menadione Approved, Nutraceutical Phase 4 58-27-5 4055
38
Phytonadione Approved, Nutraceutical Phase 4 84-80-0 4812 5284607
39
Angiotensin II Phase 4,Phase 3 68521-88-0, 11128-99-7 65143 172198
40 Atorvastatin Calcium Phase 4,Phase 3,Phase 2 134523-03-8
41 Rosuvastatin Calcium Phase 4 147098-20-2
42 Analgesics Phase 4,Phase 2,Phase 3,Phase 1
43 calcium channel blockers Phase 4,Phase 3,Phase 2,Phase 1
44 diuretics Phase 4,Phase 1,Phase 2
45
protease inhibitors Phase 4,Phase 3,Phase 2
46 Adrenergic Agents Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1
47 Natriuretic Agents Phase 4,Phase 3,Phase 1,Phase 2
48 Adrenergic Agonists Phase 4,Phase 3,Phase 1,Phase 2
49 Adrenergic Antagonists Phase 4,Phase 3,Phase 1,Early Phase 1
50 Adrenergic alpha-2 Receptor Agonists Phase 4,Phase 3,Phase 1,Phase 2

Interventional clinical trials:

(show top 50) (show all 871)
id Name Status NCT ID Phase
1 Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization Unknown status NCT01029938 Phase 4
2 Prophylactic Mesh Implantation After Abdominal Aortic Aneurysm Repair Unknown status NCT01353443 Phase 4
3 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4
4 Comparison of Beta-blocker Versus Angiotensin Receptor Blocker for Suppression of Aneurysm Expansion in Patients With Small Abdominal Aortic Aneurysm and Hypertension (BASE Trial) Unknown status NCT01904981 Phase 4
5 Immunonutrition and Thoracoabdominal Aorta Aneurysm Repair Unknown status NCT00339053 Phase 4
6 Effectiveness of Acetazolamide in Reducing Paralysis of the Leg in Patients Undergoing Aortic Aneurysm Surgery Surgery Unknown status NCT01889498 Phase 4
7 HYdrogel Coil Versus Bare Platinum Coil in Recanalization Imaging Data Study Unknown status NCT01516658 Phase 4
8 Arterial Catheter to Monitor Glycemia Unknown status NCT01176279 Phase 4
9 Tranexamic Acid in Major Vascular Surgery Unknown status NCT02335359 Phase 4
10 Efficacy of Xience/Promus Versus Cypher in rEducing Late Loss After stENTing Unknown status NCT00698607 Phase 4
11 Prospective, Multicenter Study of the Second Generation Antimicrobial Graft in the Abdominal Position Unknown status NCT00824109 Phase 4
12 Device Closure Versus Medical Therapy for Cryptogenic Stroke Patients With High-Risk Patent Foramen Ovale (DEFENSE-PFO) Unknown status NCT01550588 Phase 4
13 Statin and Angiotensin-converting Enzyme Inhibitor on Symptoms in Patients With SCAD Unknown status NCT02008786 Phase 4
14 A Morbidity-Mortality and Remodeling Study With Valsartan Unknown status NCT00133328 Phase 4
15 Aneurysm Wall Histology Registry Completed NCT01444664 Phase 4
16 MAPS Trial: Matrix And Platinum Science Completed NCT00396981 Phase 4
17 Post-Approval Trial of the Talent™ Abdominal Stent Graft to Treat Aortic Aneurysms Completed NCT00816062 Phase 4
18 Endovascular Repair of Descending Thoracic Aortic Aneurysms Completed NCT00802984 Phase 4
19 Endovascular Repair of Abdominal Aortic Aneurysms Completed NCT00803075 Phase 4
20 GORE EXCLUDER® Endoprosthesis - Low Permeability in Treatment of Abdominal Aortic Aneurysms Completed NCT00593814 Phase 4
21 Standard Open Surgery Versus Endovascular Repair of Abdominal Aortic Aneurysm (AAA) Completed NCT00094575 Phase 4
22 TRAIL: Treatment of Intracranial Aneurysms With LVIS® System Completed NCT02921711 Phase 4
23 Statin Use in Abdominal Aortic Aneurysm Repair Completed NCT01062802 Phase 4
24 Opioid-potentiated Volative Anaesthetic Vs. Remifentanil And Propofol During Abdominal Aortic Aneurysm Surgery Completed NCT00538421 Phase 4
25 Role of Propofol Postconditioning on Oxidative Stress and Cognitive Function Completed NCT02691416 Phase 4
26 Fibrinogen as an Alternative to FFP in Aortic Surgery. Completed NCT00994045 Phase 4
27 PRET: Patients Prone to Recurrence After Endovascular Treatment Completed NCT00626912 Phase 4
28 The Registry to Study Safety and Performance of the CORDIS Vascular Reconstruction Device and Delivery System Completed NCT00486226 Phase 4
29 Effects of a Surgery-induced Peripheral Inflammatory Response on the Blood Brain Barrier Completed NCT00878371 Phase 4
30 Prevalence of Abdominal Aortic Aneurysm in Patients Undergoing Coronary Angiography Completed NCT01239225 Phase 4
31 Epidural Versus Wound Infusion Plus Morphine Bolus in Open Abdominal Aortic Aneurysm Repair Completed NCT02677532 Phase 4
32 The Pharmacokinetics of Opioids and Sedative/Hypnotics During Selective Cerebral Perfusion Completed NCT00494598 Phase 4
33 Thoracoabdominal Arortic CTA Study Completed NCT02291718 Phase 4
34 A Better Choice for Patients Undergoing Endovascular Coil Embolization Completed NCT01722409 Phase 4
35 Trial to Assess the Efficacy of Combination Formula of Aspirin Plus Clopidogrel in Patients With Coronary Stent Completed NCT02410083 Phase 4
36 Researching AXIUM Coiling Experience and Recanalization (RACER) Completed NCT00703794 Phase 4
37 Vasculopathic Injury and Plasma as Endothelial Rescue - OCTAplas Trial (EudraCT no. 2014-000452-28) Completed NCT02253082 Phase 4
38 Atorvastatin in Perioperative Vascular Surgery - Pilot Study Completed NCT00610545 Phase 4
39 A Controlled Trial of Effectiveness of a Backward Walking Program in Patients Recovering From Abdominal Aorta Surgery Completed NCT00819936 Phase 4
40 Comparison of Neuroprotection by Propofol and Desflurane for POCD Following Subarachnoid Hemorrhage Surgery Completed NCT02987218 Phase 4
41 Randomized Trial of Pulsatile vs Non Pulsatile Perfusion on Short Term Changes in Kidney Function Using an Intra-Aortic Ballooon Pump During Cardioplegic Arrest in Patients Undergoing Myocardial Reperfusion Completed NCT00454428 Phase 4
42 Study of Pain, Anxiety and Complications Related to Cannulation of Arteriovenous (AV) Fistula in Chronic Hemodialysis Patients Completed NCT00544492 Phase 4
43 XIENCE V: SPIRIT WOMEN Sub-study Completed NCT01182428 Phase 4
44 Add-on Effects of Valsartan on Morbi- Mortality (KYOTO HEART Study) Completed NCT00149227 Phase 4
45 OlmeSartan and Calcium Antagonists Randomized (OSCAR) Study Completed NCT00134160 Phase 4
46 Stenting in the Treatment of Aneurysm Trial Recruiting NCT01340612 Phase 4
47 TARGET Intracranial Aneurysm Coiling Registry Recruiting NCT01748903 Phase 4
48 LARGE Aneurysm Randomized Trial: Flow Diversion Versus Traditional Endovascular Coiling Therapy Recruiting NCT01762137 Phase 4
49 Eplerenone in the Management of Abdominal Aortic Aneurysms Recruiting NCT02345590 Phase 4
50 Seizure Prophylaxis in Aneurysm Repair Recruiting NCT01801072 Phase 4

Search NIH Clinical Center for Aneurysm

Genetic Tests for Aneurysm

Genetic tests related to Aneurysm:

id Genetic test Affiliating Genes
1 Aneurysm 29

Anatomical Context for Aneurysm

MalaCards organs/tissues related to Aneurysm:

39
Bone, Brain, Heart, Kidney, Spinal Cord, Lung, Endothelial

Publications for Aneurysm

Articles related to Aneurysm:

(show top 50) (show all 8474)
id Title Authors Year
1
Mechanical behavior of the abdominal aortic aneurysm assessed by biaxial tests in the rat xenograft model. ( 28527353 )
2017
2
Fenofibrate in the management of AbdoMinal aortic anEurysm (FAME): study protocol for a randomised controlled trial. ( 28049491 )
2017
3
Giant symptomatic aneurysm secondary to hereditary hemorrhagic telangiectasia of a main hepatic artery with aberrant origin in superior mesenteric artery. ( 28461180 )
2017
4
Late presentation of hypertrophic cardiomyopathy with apical aneurysm. ( 28052918 )
2017
5
A New Mouse Model for Introduction of Aortic Aneurysm by Implantation of Deoxycorticosterone Acetate Pellets or Aldosterone Infusion in the Presence of High Salt. ( 28500602 )
2017
6
Bile-ated Cell Death Decreases Aortic Aneurysm Formation. ( 28089083 )
2017
7
Factors associated with development of coronary artery aneurysms after Kawasaki disease are similar for those treated promptly and those with delayed or no treatment. ( 28089146 )
2017
8
MicroRNA-181b Controls Atherosclerosis and Aneurysms Through Regulation of TIMP-3 and Elastin. ( 27756793 )
2017
9
Recombinant adeno-associated virus vector carrying the thrombomodulin lectin-like domain for the treatment of abdominal aortic aneurysm. ( 28525804 )
2017
10
Proximal Aortic Neck Progression: Before and After Abdominal Aortic Aneurysm Treatment. ( 28523269 )
2017
11
Cervical artery tortuosity is associated with intracranial aneurysm. ( 28073311 )
2017
12
Novel ELN mutation in a family with supravalvular aortic stenosis and intracranial aneurysm. ( 27866049 )
2017
13
Lifestyle and Risk of Screening-Detected Abdominal Aortic Aneurysm in Men. ( 28490522 )
2017
14
Virtual 3-Dimensional Computed Tomographic Surgical Planning for Severe Aortic Coarctation/Aneurysm in the Setting of Bicuspid Aortic Valve. ( 28033077 )
2017
15
Mild aerobic exercise blocks elastin fiber fragmentation and aortic dilatation in a mouse model of Marfan syndrome associated aortic aneurysm. ( 28385916 )
2017
16
Atherosclerotic vascular diseases have really the same risk factors? Comparison between large abdominal aortic aneurysm and obstructive non-coronary arterial disease. ( 28509621 )
2017
17
Simple Identification of the Adamkiewicz Artery in Extended Thoracoabdominal Aortic Aneurysm Repair. ( 28528073 )
2017
18
Predicting the Need for Intra-operative Large Volume Blood Transfusions During Thoraco-abdominal Aortic Aneurysm Repair. ( 28089084 )
2017
19
Experiences of the screening process and the diagnosis abdominal aortic aneurysm among 65-year-old men from invitation to a 1-year surveillance. ( 28527730 )
2017
20
Aortic valve prolapse misdiagnosed as aortic sinus aneurysm in patients with ventricular septal defect. Analysis of the echocardiographic findings. ( 28397952 )
2017
21
The Consequences of Real Life Practice of Early Abdominal Aortic Aneurysm Repair: A Cost-Benefit Analysis. ( 28506561 )
2017
22
Ruptured extradural vertebral artery aneurysm in a patient with neurofibromatosis type 1. ( 28057401 )
2017
23
Complex coronary artery aneurysm. ( 27862313 )
2017
24
Coronary Artery Aneurysm After Bioresorbable Vascular Scaffold Implantation With Post-Dilation: Is Less More? ( 28017314 )
2017
25
Rupture of ascending aortic aneurysm in to the pulmonary artery: rare presentation with grave prognosis. ( 28062566 )
2017
26
Definitive Endovascular Repair of a Brucellar Descending Thoracic Aortic Aneurysm. ( 28513124 )
2017
27
Reoperation rates after open and endovascular abdominal aortic aneurysm repairs. ( 28073669 )
2017
28
The effects of preoperative cardiology consultation prior to elective abdominal aortic aneurysm repair on patient morbidity. ( 28059000 )
2017
29
Fusiform Left Carotid-Ophthalmic Artery Aneurysm Presenting with Central Retinal Artery Occlusion. ( 27865695 )
2017
30
Late Presentation of Aortic Aneurysm and Dissection Following Cardiac Catheterization. ( 28515825 )
2017
31
Pharmacological treatment of vascular risk factors for reducing mortality and cardiovascular events in patients with abdominal aortic aneurysm. ( 28079254 )
2017
32
Translational Relevance and Recent Advances of Animal Models of Abdominal Aortic Aneurysm. ( 28062500 )
2017
33
Pipeline embolization device for the treatment of a traumatic intracranial aneurysm in a child. ( 28064352 )
2017
34
Treatment challenges in neurogenic stress cardiomyopathy following aneurysmal subarachnoid hemorrhage. ( 28084277 )
2017
35
Update on Screening for Abdominal Aortic Aneurysm. ( 28526395 )
2017
36
Contained ruptured abdominal aortic aneurysm presenting as cauda equina syndrome. ( 28062419 )
2017
37
Correction to: Diverse Requirements for Efficient Population Screening for Abdominal Aortic Aneurysm: From Program Management to Maintaining Skills in Open Repair. ( 28069719 )
2017
38
Resolution of giant basilar artery aneurysm compression and reversal of sensorineural hearing loss with use of a flow diverter: case report. ( 28452658 )
2017
39
Spontaneous regression of cardiac sarcoidosis resulting in total occlusion of coronary artery and ventricular aneurysm. ( 28063417 )
2017
40
Transapical aortic perfusion using a deep hypothermic procedure to prevent dissecting lung injury during re-do thoracoabdominal aortic aneurysm surgery. ( 28526092 )
2017
41
Small versus Large Ruptured Intracranial Aneurysm: Concerns with the Site of Aneurysm. ( 28088803 )
2017
42
Endovascular repair of a short neck abdominal aortic aneurysm with a physician-modified Vascutek Anaconda stent-graft. ( 28495541 )
2017
43
Successful Treatment With Electroconvulsive Therapy of a Patient With Bipolar Disorder and a 7-mm Cerebral Aneurysm. ( 28072662 )
2017
44
Frontal skull osteoblastoma with aneurysmal bone cyst-like changes associated with trauma during pregnancy: a case report. ( 27853880 )
2017
45
Infrarenal Infected Aortic Aneurysm Caused by Streptococcus pyogenes. ( 28503338 )
2017
46
Giant Thoracic Aortic Aneurysm Manifested as Dysphagia and Dyspnea. ( 28007285 )
2017
47
Reporting individual surgeon outcomes does not lead to risk aversion in abdominal aortic aneurysm surgery. ( 28071950 )
2017
48
Treatment of aneurysmal bone cysts by percutaneous CT-guided injection of calcitonin and steroid. ( 27743037 )
2017
49
Under-Utilization of Routine Ultrasound Surveillance after Endovascular Aortic Aneurysm Repair. ( 28501663 )
2017
50
Double-lumen atherosclerotic abdominal aortic aneurysm. ( 28010862 )
2017

Variations for Aneurysm

Expression for Aneurysm

Search GEO for disease gene expression data for Aneurysm.

Pathways for Aneurysm

Pathways related to Aneurysm according to GeneCards Suite gene sharing:

(show all 12)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.83 ACTA2 COL3A1 ELN FBN1 MMP12 MMP13
2
Show member pathways
12.6 COL3A1 ELN LOX MMP13 MMP9
3 11.95 MMP12 MMP9 TGFBR1 TGFBR2
4
Show member pathways
11.88 COL3A1 ELN FBN1 LOX MFAP5 MMP12
5 11.68 COL3A1 TGFBR1 TGFBR2
6
Show member pathways
11.67 MMP12 MMP13 MMP9
7
Show member pathways
11.52 LOX TGFBR1 TGFBR2
8
Show member pathways
11.42 ELN FBN1 LOX MFAP5
9 11.27 MMP13 TGFBR1 TGFBR2
10 11.24 COL3A1 MMP12 MMP13 MMP9
11 11.1 ACTA2 MYH11 MYLK
12 10.9 FBN1 TGFBR1 TGFBR2

GO Terms for Aneurysm

Cellular components related to Aneurysm according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.86 ACTA2 COL3A1 FBN1 LOX MFAP5 MMP12
2 extracellular matrix GO:0031012 9.55 COL3A1 FBN1 MMP12 MMP13 MMP9
3 collagen trimer GO:0005581 9.54 COL3A1 LOX MMP13
4 microfibril GO:0001527 9.32 FBN1 MFAP5
5 proteinaceous extracellular matrix GO:0005578 9.23 COL3A1 ELN FBN1 LOX MFAP5 MMP12
6 transforming growth factor beta receptor complex GO:0070022 8.96 TGFBR1 TGFBR2

Biological processes related to Aneurysm according to GeneCards Suite gene sharing:

(show all 18)
id Name GO ID Score Top Affiliating Genes
1 muscle contraction GO:0006936 9.73 ACTA2 MYH11 MYLK
2 skeletal system development GO:0001501 9.73 COL3A1 FBN1 MMP9 TGFBR1
3 transforming growth factor beta receptor signaling pathway GO:0007179 9.72 COL3A1 TGFBR1 TGFBR2
4 heart development GO:0007507 9.72 COL3A1 FBN1 LOX TGFBR1 TGFBR2
5 smooth muscle contraction GO:0006939 9.58 MYH11 MYLK
6 collagen fibril organization GO:0030199 9.58 COL3A1 LOX TGFBR1
7 transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 9.57 TGFBR1 TGFBR2
8 collagen catabolic process GO:0030574 9.56 COL3A1 MMP12 MMP13 MMP9
9 wound healing GO:0042060 9.55 COL3A1 LOX MMP12 TGFBR1 TGFBR2
10 pathway-restricted SMAD protein phosphorylation GO:0060389 9.54 TGFBR1 TGFBR2
11 supramolecular fiber organization GO:0097435 9.52 COL3A1 MFAP5
12 response to cholesterol GO:0070723 9.51 TGFBR1 TGFBR2
13 elastic fiber assembly GO:0048251 9.49 LOX MYH11
14 growth plate cartilage development GO:0003417 9.48 MMP13 TGFBR2
15 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation GO:1905007 9.46 TGFBR1 TGFBR2
16 extracellular matrix organization GO:0030198 9.43 COL3A1 ELN FBN1 LOX MFAP5 MMP9
17 aorta smooth muscle tissue morphogenesis GO:0060414 9.37 COL3A1 MYLK
18 extracellular matrix disassembly GO:0022617 9.02 ELN FBN1 MMP12 MMP13 MMP9

Molecular functions related to Aneurysm according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 metalloendopeptidase activity GO:0004222 9.58 MMP12 MMP13 MMP9
2 collagen binding GO:0005518 9.43 MMP12 MMP13 MMP9
3 transforming growth factor beta binding GO:0050431 9.37 TGFBR1 TGFBR2
4 transmembrane receptor protein serine/threonine kinase activity GO:0004675 9.32 TGFBR1 TGFBR2
5 transforming growth factor beta-activated receptor activity GO:0005024 9.16 TGFBR1 TGFBR2
6 SMAD binding GO:0046332 9.13 COL3A1 TGFBR1 TGFBR2
7 extracellular matrix structural constituent GO:0005201 8.92 COL3A1 ELN FBN1 MFAP5

Sources for Aneurysm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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