MCID: ANR009
MIFTS: 38

Aneurysmal Bone Cysts malady

Categories: Rare diseases, Bone diseases

Aliases & Classifications for Aneurysmal Bone Cysts

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Aliases & Descriptions for Aneurysmal Bone Cysts:

Name: Aneurysmal Bone Cysts 52 35 48 12
Bone Cysts, Aneurysmal 68
 
Bone Cysts Aneurysmal 50

Classifications:



External Ids:

OMIM52 606179
ICD1030 M85.5

Summaries for Aneurysmal Bone Cysts

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Wikipedia:71 Aneurysmal bone cyst, abbreviated ABC, is an osteolytic bone neoplasm characterized by several... more...

MalaCards based summary: Aneurysmal Bone Cysts, also known as bone cysts, aneurysmal, is related to aneurysm and osteopetrosis, autosomal recessive 7, and has symptoms including pain An important gene associated with Aneurysmal Bone Cysts is ANBC (Aneurysmal Bone Cysts), and among its related pathways are Osteoclast Signaling and Transcription_Role of VDR in regulation of genes involved in osteoporosis. Affiliated tissues include bone, endothelial and bone marrow.

Description from OMIM:52 606179

Related Diseases for Aneurysmal Bone Cysts

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Diseases related to Aneurysmal Bone Cysts via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 55)
idRelated DiseaseScoreTop Affiliating Genes
1aneurysm10.8
2osteopetrosis, autosomal recessive 710.3TNFRSF11A, TNFSF11
3chondroblastoma10.3
4hemorrhagic shock and encephalopathy syndrome10.3TNFRSF11A, TNFSF11
5inflammatory liposarcoma10.2TNFRSF11A, TNFSF11
6fibrous dysplasia10.2
7pneumatosis cystoides intestinalis10.2TNFRSF11A, TNFSF11
8osteoblastoma10.2
9impotence10.2CALCA, TNFSF11
10fibroma10.1
11giant cell tumor10.1
12ossifying fibroma10.1
13phka2-related phosphorylase kinase deficiency10.1GSK3B, MAPT
14bacillary angiomatosis10.0CALCA, TNFSF11
15intraorbital meningioma10.0SLCO1A2, SLCO4A1
16acquired hyperkeratosis10.0CALCA, TNFSF11
17cervicitis10.0
18giant cell reparative granuloma9.9
19tibial hemimelia9.9CALCA, TNFRSF11A, TNFSF11
20anaerobic meningitis9.9CALCA, TNFRSF11A, TNFSF11
21physical disorder9.9CALCA, TNFRSF11A, TNFSF11
22bone deterioration disease9.9CALCA, TNFRSF11A, TNFSF11
23scrotal carcinoma9.9CALCA, TNFSF11
24neuroma9.9CALCA, TNFRSF11A, TNFSF11
25lung occult small cell carcinoma9.9CALCA, TNFRSF11A, TNFSF11
26chondromyxoid fibroma9.8
27bone resorption disease9.8TNFRSF11A, TNFSF11
28cherubism9.8
29chondrosarcoma9.8
30ameloblastoma9.8
31myositis9.8
32myositis ossificans9.8
33juvenile ossifying fibroma9.8
34gastrointestinal stromal tumor9.6
35focal dermal hypoplasia9.6
36bone fracture9.6
37hydrocephalus9.6
38angiosarcoma9.6
39partial third-nerve palsy9.6
40horner's syndrome9.6
41tooth resorption9.6
42obstructive hydrocephalus9.6
43thoracic outlet syndrome9.6
44histiocytosis9.6
45mesenchymal chondrosarcoma9.6
46clear cell chondrosarcoma9.6
47neuropathy9.6
48exophthalmos9.6
49fasciitis9.6
50enchondroma9.6

Graphical network of the top 20 diseases related to Aneurysmal Bone Cysts:



Diseases related to aneurysmal bone cysts

Symptoms & Phenotypes for Aneurysmal Bone Cysts

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Clinical features from OMIM:

606179

UMLS symptoms related to Aneurysmal Bone Cysts:


pain

Drugs & Therapeutics for Aneurysmal Bone Cysts

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Aneurysmal Bone Cysts

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Aneurysmal Bone Cysts cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Aneurysmal Bone Cysts:
Bone marrow-derived mesenchymal cell transplantation for bone cysts
Embryonic/Adult Cultured Cells Related to Aneurysmal Bone Cysts:
Bone marrow-derived mesenchymal stem cells (family)

Genetic Tests for Aneurysmal Bone Cysts

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Anatomical Context for Aneurysmal Bone Cysts

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MalaCards organs/tissues related to Aneurysmal Bone Cysts:

36
Bone, Endothelial, Bone marrow

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Aneurysmal Bone Cysts:
id TissueAnatomical CompartmentCell Relevance
1 BoneBone MarrowBone Marrow Stromal Cells Potential therapeutic candidate

Publications for Aneurysmal Bone Cysts

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Articles related to Aneurysmal Bone Cysts:

(show top 50)    (show all 288)
idTitleAuthorsYear
1
Frontal skull osteoblastoma with aneurysmal bone cyst-like changes associated with trauma during pregnancy: a case report. (27853880)
2017
2
Treatment of aneurysmal bone cysts by percutaneous CT-guided injection of calcitonin and steroid. (27743037)
2017
3
Craniospinal Polyostotic Fibrous Dysplasia, Aneurysmal Bone Cysts, and Chiari Type 1 Malformation Coexistence in a Patient with McCune-Albright Syndrome. (27161212)
2016
4
Aneurysmal Bone Cyst: An Uncommon Secondary Event in Calcaneal Chondroblastoma. (27504302)
2016
5
Aneurysmal Bone Cyst Arising from the First Rib: A Rare Cause of Thoracic Outlet Syndrome. (28018833)
2016
6
Radiotherapy for aneurysmal bone cysts : AA rare indication. (27957589)
2016
7
Selective arterial Embolisation of Aneurysmal Bone Cysts ofA the Sacrum: a promising Alternative to Surgery. (26695847)
2016
8
Current management of aneurysmal bone cysts. (27778155)
2016
9
Giant Cell Tumor with Secondary Aneurysmal Bone Cyst Shows Heterogeneous Metabolic Pattern on (18)F-FDG PET/CT: A Case Report. (27994691)
2016
10
Interest of Denosumab for the Treatment of Giant-cells Tumors and Aneurysmal Bone Cysts of the Spine. About Nine Cases. (27244112)
2016
11
How effective is embolization with N-2-butyl-cyanoacrylate for aneurysmal bone cysts? (27933423)
2016
12
Conversion of Aneurysmal Bone Cyst into Fibrous Dysplasia: A Rare Pediatric Case Report. (27408470)
2016
13
Surgical treatment of active or aggressive aneurysmal bone cysts in children. (25812030)
2015
14
Current Strategies for the Treatment of Aneurysmal Bone Cysts. (26793296)
2015
15
Aneurysmal Bone Cysts of the Hand, Wrist, andA Forearm. (26253603)
2015
16
A case report of granular cell ameloblastoma associated with aneurysmal bone cyst like features. (26538973)
2015
17
Aneurysmal bone cyst with fibrous dysplasia resulting in partial third nerve palsy. (25863863)
2015
18
Psammous desmo-osteoblastoma with concomitant aneurysmal bone cyst of mandible. (26389053)
2015
19
Percutaneous Doxycycline Treatment of Juxtaphyseal Aneurysmal Bone Cysts. (25985367)
2015
20
A rare case of osteoblastoma associated to aneurysmal bone cyst of the spine. Case report. (26204456)
2015
21
Differential diagnostic value of "blue reticulated chondroid-like material" in aneurysmal bone cysts: a classic histopathologic analysis of 215 cases. (25972324)
2015
22
Unusual localizations of unicameral bone cysts and aneurysmal bone cysts: A retrospective review of 451 cases. (26280957)
2015
23
Radiation Therapy for Aneurysmal Bone Cysts. (26165419)
2015
24
An endolymphatic sac tumor with imaging features of aneurysmal bone cysts: differential diagnostic considerations. (24881035)
2014
25
USP6-induced neoplasms: the biologic spectrum of aneurysmal bone cyst and nodular fasciitis. (23769422)
2014
26
Clear cell chondrosarcoma with secondary aneurysmal bone cyst changes. (24664395)
2014
27
Aneurysmal bone cysts of the spine: two case reports. (25620988)
2014
28
Is curettage and high-speed burring sufficient treatment for aneurysmal bone cysts? (25048282)
2014
29
Juvenile psammomatoid ossifying fibroma with aneurysmal bone cyst in the posterior mandible. (25374619)
2014
30
Assessment of 120 maxillofacial aneurysmal bone cysts: a nationwide quest to understand this enigma. (24931106)
2014
31
Treatments for primary aneurysmal bone cysts of the cervical spine: experience of 14 cases. (25430453)
2014
32
Intraspinal dural-based primary osteoblastoma with aneurysmal bone cyst-like change. (24984761)
2014
33
Chondroblastoma of the patella with aneurysmal bone cyst. (24683664)
2014
34
Bipolar electric cauterization as adjuvant treatment after curettage of aneurysmal bone cysts of the hand. (24317236)
2014
35
Aneurysmal bone cysts: do simple treatments work? (24532435)
2014
36
Aneurysmal bone cysts: denosumab extends its reach. (24837849)
2014
37
Aneurysmal bone cysts of the spine: treatment options and considerations. (25059450)
2014
38
Chondroblastoma with secondary aneurysmal bone cyst of the capitate. (24810829)
2014
39
Secondary aneurysmal bone cystic change of the chondroblastoma, mistaken for a primary aneurysmal bone cyst in the patella. (24639947)
2014
40
Functional outcomes and quality of life following surgical treatment of aneurysmal bone cysts of the pelvis in children. (24817630)
2014
41
Targeting receptor-activator of nuclear kappaB ligand in aneurysmal bone cysts: verification of target and therapeutic response. (24726460)
2014
42
Effect of adjuvant therapies on recurrence in aneurysmal bone cysts. (25429574)
2014
43
Destructive osteoblastoma with secondary aneurysmal bone cyst of cervical vertebra in an 11-year-old boy: case report. (24482719)
2014
44
Denosumab: a potential new and innovative treatment option for aneurysmal bone cysts. (23455951)
2013
45
Giant cell tumor with secondary aneurysmal bone cyst: a unique presentation with an ossified extraosseous soft tissue mass. (23708046)
2013
46
Gastrointestinal stromal tumor of the ampulla of Vater with osteoclastic giant cells, osteoid-like matrix deposition, and aneurysmal bone cyst-like features. (23036260)
2013
47
Aneurysmal bone cysts. (24049942)
2013
48
A comparison of cyst wall curettage and en bloc excision in the treatment of aneurysmal bone cysts. (23701661)
2013
49
Percutaneous doxycycline treatment of aneurysmal bone cysts with low recurrence rate: a preliminary report. (23670673)
2013
50
Sclerotherapy of primary aneurysmal bone cysts: comment to Lambot-Juhan et al. (23184092)
2013

Variations for Aneurysmal Bone Cysts

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Expression for genes affiliated with Aneurysmal Bone Cysts

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Search GEO for disease gene expression data for Aneurysmal Bone Cysts.

Pathways for genes affiliated with Aneurysmal Bone Cysts

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GO Terms for genes affiliated with Aneurysmal Bone Cysts

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Cellular components related to Aneurysmal Bone Cysts according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1growth coneGO:003042610.1CDK5, GSK3B, MAPT
2axonGO:00304249.6CALCA, CDK5, GSK3B, MAPT
3plasma membraneGO:00058865.7CDH11, CDK5, GBP1, GSK3B, MAPT, SLCO1A2

Biological processes related to Aneurysmal Bone Cysts according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1mammary gland alveolus developmentGO:006074910.5TNFRSF11A, TNFSF11
2osteoclast differentiationGO:003031610.4TNFRSF11A, TNFSF11
3positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signalingGO:007184810.3TNFRSF11A, TNFSF11
4positive regulation of fever generation by positive regulation of prostaglandin secretionGO:007181210.3TNFRSF11A, TNFSF11
5axon extensionGO:004867510.3CDK5, MAPT
6positive regulation of axon extensionGO:004577310.2GSK3B, MAPT
7peptidyl-threonine phosphorylationGO:001810710.2CDK5, GSK3B
8ossificationGO:000150310.2CDH11, TNFRSF11A, TNFSF11
9positive regulation of neuron deathGO:190121610.1CDK5, GSK3B
10monocyte chemotaxisGO:00025489.9CALCA, TNFRSF11A, TNFSF11
11axonogenesisGO:00074099.9CDK5, GSK3B, MAPT
12TNFSF11-mediated signaling pathwayGO:00718479.9TNFRSF11A, TNFSF11
13sodium-independent organic anion transportGO:00432529.3SLCO1A2, SLCO3A1, SLCO4A1

Molecular functions related to Aneurysmal Bone Cysts according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine bindingGO:00199559.7GBP1, TNFRSF11A
2tau-protein kinase activityGO:00503219.7CDK5, GSK3B
3sodium-independent organic anion transmembrane transporter activityGO:00153479.5SLCO1A2, SLCO3A1, SLCO4A1

Sources for Aneurysmal Bone Cysts

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet