MCID: ANR009
MIFTS: 37

Aneurysmal Bone Cysts malady

Rare diseases, Bone diseases categories

Aliases & Classifications for Aneurysmal Bone Cysts

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Aliases & Descriptions for Aneurysmal Bone Cysts:

Name: Aneurysmal Bone Cysts 49 32 11 45
Bone Cysts, Aneurysmal 65
 
Bone Cysts Aneurysmal 47


Classifications:



External Ids:

OMIM49 606179
ICD1027 M85.5

Summaries for Aneurysmal Bone Cysts

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Wikipedia:68 Aneurysmal bone cyst, abbreviated ABC, is an osteolytic bone neoplasm characterized by several... more...

MalaCards based summary: Aneurysmal Bone Cysts, also known as bone cysts, aneurysmal, is related to aneurysm and chondroblastoma. An important gene associated with Aneurysmal Bone Cysts is ANBC (Aneurysmal Bone Cysts), and among its related pathways are Osteoclast Signaling and Transcription_Role of VDR in regulation of genes involved in osteoporosis. Affiliated tissues include bone, endothelial and bone marrow, and related mouse phenotype integument.

Description from OMIM:49 606179

Related Diseases for Aneurysmal Bone Cysts

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Diseases related to Aneurysmal Bone Cysts via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 55)
idRelated DiseaseScoreTop Affiliating Genes
1aneurysm11.3
2chondroblastoma10.8
3fibrous dysplasia10.7
4osteoblastoma10.7
5fibroma10.7
6giant cell tumor10.6
7ossifying fibroma10.6
8cervicitis10.5
9giant cell reparative granuloma10.4
10chondromyxoid fibroma10.4
11cherubism10.3
12chondrosarcoma10.3
13ameloblastoma10.3
14myositis ossificans10.3
15myositis10.3
16juvenile ossifying fibroma10.3
17gastrointestinal stromal tumor10.1
18focal dermal hypoplasia10.1
19bone fracture10.1
20hydrocephalus10.1
21langerhans-cell histiocytosis10.1
22horner's syndrome10.1
23exophthalmos10.1
24obstructive hydrocephalus10.1
25clear cell chondrosarcoma10.1
26partial third-nerve palsy10.1
27angiosarcoma10.1
28fasciitis10.1
29histiocytosis10.1
30mesenchymal chondrosarcoma10.1
31neuropathy10.1
32tooth resorption10.1
33enchondroma10.1
34endolymphatic sac tumor10.1
35osteofibrous dysplasia10.1
36endotheliitis10.1
37monostotic fibrous dysplasia10.1
38paget disease of bone 2, early-onset10.1TNFRSF11A, TNFSF11
39hemorrhagic fever10.1TNFRSF11A, TNFSF11
40polycystic bone disease10.1TNFRSF11A, TNFSF11
41cannabis dependence10.0CALCA, TNFRSF11A
42toxoplasmosis10.0TNFRSF11A, TNFSF11
43primary syphilis10.0TNFRSF11A, TNFSF11
44jaw cancer10.0TNFRSF11A, TNFSF11
45paget disease of bone 5, juvenile-onset9.9CALCA, TNFRSF11A, TNFSF11
46pulmonary type ovarian small cell carcinoma9.9CALCA, TNFSF11
47marcus gunn phenomenon9.9CALCA, TNFRSF11A, TNFSF11
48methylmalonic aciduria and homocystinuria type cble9.9CALCA, TNFRSF11A, TNFSF11
49bone structure disease9.9CALCA, TNFRSF11A, TNFSF11
50gingival disease9.9CALCA, TNFRSF11A, TNFSF11

Graphical network of the top 20 diseases related to Aneurysmal Bone Cysts:



Diseases related to aneurysmal bone cysts

Symptoms for Aneurysmal Bone Cysts

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Clinical features from OMIM:

606179

Drugs & Therapeutics for Aneurysmal Bone Cysts

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Aneurysmal Bone Cysts

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Aneurysmal Bone Cysts cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Aneurysmal Bone Cysts:
Bone marrow-derived mesenchymal cell transplantation for bone cysts
Embryonic/Adult Cultured Cells Related to Aneurysmal Bone Cysts:
Bone marrow-derived mesenchymal stem cells (family)

Genetic Tests for Aneurysmal Bone Cysts

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Anatomical Context for Aneurysmal Bone Cysts

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MalaCards organs/tissues related to Aneurysmal Bone Cysts:

33
Bone, Endothelial, Bone marrow

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Aneurysmal Bone Cysts:
id TissueAnatomical CompartmentCell Relevance
1 BoneBone MarrowBone Marrow Stromal Cells Potential therapeutic candidate

Animal Models for Aneurysmal Bone Cysts or affiliated genes

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MGI Mouse Phenotypes related to Aneurysmal Bone Cysts:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.4CALCA, CDH11, CDK5, MAPT, TNFRSF11A, TNFSF11

Publications for Aneurysmal Bone Cysts

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Articles related to Aneurysmal Bone Cysts:

(show top 50)    (show all 273)
idTitleAuthorsYear
1
Aneurysmal bone cyst with fibrous dysplasia resulting in partial third nerve palsy. (25863863)
2015
2
Psammous desmo-osteoblastoma with concomitant aneurysmal bone cyst of mandible. (26389053)
2015
3
Percutaneous Doxycycline Treatment of Juxtaphyseal Aneurysmal Bone Cysts. (25985367)
2015
4
Aneurysmal bone cysts: do simple treatments work? (24532435)
2014
5
An endolymphatic sac tumor with imaging features of aneurysmal bone cysts: differential diagnostic considerations. (24881035)
2014
6
Aneurysmal bone cysts: denosumab extends its reach. (24837849)
2014
7
Sclerotherapy with polidocanol for treatment of aneurysmal bone cysts. (24171682)
2013
8
Denosumab: a potential new and innovative treatment option for aneurysmal bone cysts. (23455951)
2013
9
Aneurysmal bone cyst within fibrous dysplasia of the anterior skull base: continued intracranial extension after endoscopic resections requiring craniofacial approach with free tissue transfer reconstruction. (23435492)
2013
10
Active aneurysmal bone cysts in children: possible evolution after biopsy. (23904901)
2012
11
Giant pediatric aneurysmal bone cysts of the occipital bone: case report and review of the literature. (21723459)
2011
12
Temporal bone chondroblastoma with secondary aneurysmal bone cyst presenting as an intracranial mass with clinical seizure activity. (21514167)
2011
13
Fibrous dysplasia and aneurysmal bone cyst of the skull base presenting with blindness: a report of a rare locally aggressive example. (21396116)
2011
14
Factors associated with recurrence of primary aneurysmal bone cysts: is argon beam coagulation an effective adjuvant treatment? (22048101)
2011
15
Secondary aneurysmal bone cyst in fibrous dysplasia of the proximal femur. (19472953)
2009
16
A cherubism with aneurysmal bone cyst. (19386735)
2009
17
Monostotic fibrous dysplasia of a lumbar vertebral body with secondary aneurysmal bone cyst formation: a case report. (19830140)
2009
18
Aneurysmal bone cysts of the jaws. (19233862)
2009
19
Aggressive "benign" primary spine neoplasms: osteoblastoma, aneurysmal bone cyst, and giant cell tumor. (19829276)
2009
20
Radiology corner. Answer to last month's radiology case and image: chondroblastoma with secondary aneurysmal bone cyst. (18333502)
2008
21
Frequency of USP6 rearrangements in myositis ossificans, brown tumor, and cherubism: molecular cytogenetic evidence that a subset of "myositis ossificans-like lesions" are the early phases in the formation of soft-tissue aneurysmal bone cyst. (18265974)
2008
22
Femoral mesenchymal chondrosarcoma with secondary aneurysmal bone cysts mimicking a small-cell osteosarcoma. (16328381)
2006
23
Bone matrix therapy for aneurysmal bone cysts. (16037557)
2005
24
Aneurysmal bone cysts in children: complications of fibrosing agent injection. (15215542)
2004
25
Metachronous and multiple aneurysmal bone cysts: a rare variant of primary aneurysmal bone cysts. (15024646)
2004
26
Aneurysmal bone cyst arising from fibrous dysplasia of the frontal bone (2004:2b). (15162799)
2004
27
Classic adamantinoma with osteofibrous dysplasia-like foci and secondary aneurysmal bone cyst. (12574919)
2003
28
Treatment of chondroblastoma of the calcaneus with a secondary aneurysmal bone cyst using endoscopic curettage without bone grafting. (11951204)
2002
29
Surface aneurysmal bone cysts: a pictorial review. (11868083)
2002
30
Treatment of aneurysmal bone cysts with saucerization and bone marrow injection in children. (10413010)
1999
31
Arterial embolization of aneurysmal bone cysts in children. (8731423)
1996
32
Unicameral and aneurysmal bone cysts. (8649741)
1996
33
Benign osteoblastoma associated with an aneurysmal bone cyst of the mandibular ramus and condyle. (8233421)
1993
34
Case report 729. Myositis ossificans and aneurysmal bone cyst. (1626294)
1992
35
Fluid levels in aneurysmal bone cysts. (1795415)
1991
36
Immunocytochemical markers (endothelial and histiocytic) and ultrastructure of primary aneurysmal bone cysts. (3080364)
1986
37
Aneurysmal bone cysts of the patella secondary to chondroblastoma. Case reports. (3966195)
1985
38
Aneurysmal bone cysts of the spine. (4018962)
1985
39
Concurrent osteoblastoma and aneurysmal bone cyst of the ethmoid sinus: case report. (4053663)
1985
40
Fluid levels in aneurysmal bone cysts: a CT feature. (6609547)
1984
41
Bilateral aneurysmal bone cysts of the maxilla. (6936531)
1981
42
Aneurysmal bone cysts with emphasis on roentgenologic diagnosis. (7320427)
1981
43
Aneurysmal bone cysts occurring in the metacarpals: a report of three cases. (722033)
1978
44
Aneurysmal bone cysts: a clinicopathological study of 105 cases. (265751)
1977
45
Aneurysmal bone cysts. (1193666)
1975
46
Aneurysmal bone cysts penetrating the tibial epiphysis after curettage. (5100168)
1971
47
Aneurysmal bone cysts of the jaws. (5243134)
1968
48
ANEURYSMAL BONE CYSTS OF THE MANDIBLE; REPORT OF A CASE. (14199580)
1964
49
A possible case of multiple aneurysmal bone cysts. (14487445)
1962
50
Aneurysmal bone cysts of spine. (13405746)
1957

Variations for Aneurysmal Bone Cysts

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Expression for genes affiliated with Aneurysmal Bone Cysts

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Search GEO for disease gene expression data for Aneurysmal Bone Cysts.

Pathways for genes affiliated with Aneurysmal Bone Cysts

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GO Terms for genes affiliated with Aneurysmal Bone Cysts

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Cellular components related to Aneurysmal Bone Cysts according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1growth coneGO:00304269.7CDK5, GSK3B, MAPT
2plasma membraneGO:00058866.1CDH11, GBP1, GSK3B, MAPT, SLCO1A2, SLCO3A1

Biological processes related to Aneurysmal Bone Cysts according to GeneCards Suite gene sharing:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of fever generation by positive regulation of prostaglandin secretionGO:007181210.3TNFRSF11A, TNFSF11
2TNFSF11-mediated signaling pathwayGO:007184710.3TNFRSF11A, TNFSF11
3positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signalingGO:007184810.3TNFRSF11A, TNFSF11
4positive regulation of axon extensionGO:004577310.2GSK3B, MAPT
5axon extensionGO:004867510.0CDK5, MAPT
6osteoclast differentiationGO:00303169.8TNFRSF11A, TNFSF11
7monocyte chemotaxisGO:00025489.7CALCA, TNFRSF11A, TNFSF11
8ossificationGO:00015039.6CDH11, TNFRSF11A, TNFSF11
9mammary gland alveolus developmentGO:00607499.6TNFRSF11A, TNFSF11
10axonogenesisGO:00074099.5CDK5, GSK3B, MAPT
11anion transmembrane transportGO:00986569.3SLCO1A2, SLCO3A1, SLCO4A1
12sodium-independent organic anion transportGO:00432529.3SLCO1A2, SLCO3A1, SLCO4A1

Molecular functions related to Aneurysmal Bone Cysts according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1tau-protein kinase activityGO:00503219.8CDK5, GSK3B
2cytokine bindingGO:00199559.6GBP1, TNFRSF11A
3sodium-independent organic anion transmembrane transporter activityGO:00153479.0SLCO1A2, SLCO3A1, SLCO4A1

Sources for Aneurysmal Bone Cysts

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet