MCID: ANR009
MIFTS: 39

Aneurysmal Bone Cysts malady

Categories: Rare diseases, Bone diseases, Immune diseases

Aliases & Classifications for Aneurysmal Bone Cysts

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Aliases & Descriptions for Aneurysmal Bone Cysts:

Name: Aneurysmal Bone Cysts 50 33 46 12
Bone Cysts, Aneurysmal 66
 
Bone Cysts Aneurysmal 48

Classifications:



External Ids:

OMIM50 606179
ICD1028 M85.5

Summaries for Aneurysmal Bone Cysts

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Wikipedia:69 Aneurysmal bone cyst, abbreviated ABC, is an osteolytic bone neoplasm characterized by several... more...

MalaCards based summary: Aneurysmal Bone Cysts, also known as bone cysts, aneurysmal, is related to aneurysm and chondroblastoma, and has symptoms including pain An important gene associated with Aneurysmal Bone Cysts is ANBC (Aneurysmal Bone Cysts), and among its related pathways are Osteoclast Signaling and Transcription_Role of VDR in regulation of genes involved in osteoporosis. Affiliated tissues include bone, bone marrow and endothelial.

Description from OMIM:50 606179

Related Diseases for Aneurysmal Bone Cysts

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Diseases related to Aneurysmal Bone Cysts via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 56)
idRelated DiseaseScoreTop Affiliating Genes
1aneurysm10.9
2chondroblastoma10.4
3osteopetrosis, autosomal recessive 710.4TNFRSF11A, TNFSF11
4hemorrhagic shock and encephalopathy syndrome10.3TNFRSF11A, TNFSF11
5fibrous dysplasia10.3
6juvenile retinoschisis10.3TNFRSF11A, TNFSF11
7inflammatory liposarcoma10.3TNFRSF11A, TNFSF11
8pneumatosis cystoides intestinalis10.3TNFRSF11A, TNFSF11
9fibroma10.3
10osteoblastoma10.3
11giant cell tumor10.2
12impotence10.2CALCA, TNFSF11
13ossifying fibroma10.2
14phka2-related phosphorylase kinase deficiency10.1GSK3B, MAPT
15cervicitis10.1
16bacillary angiomatosis10.0CALCA, TNFSF11
17giant cell reparative granuloma10.0
18intraorbital meningioma10.0SLCO1A2, SLCO4A1
19acquired hyperkeratosis10.0CALCA, TNFSF11
20chondromyxoid fibroma10.0
21tibial hemimelia9.9CALCA, TNFRSF11A, TNFSF11
22anaerobic meningitis9.9CALCA, TNFRSF11A, TNFSF11
23physical disorder9.9CALCA, TNFRSF11A, TNFSF11
24bone deterioration disease9.9CALCA, TNFRSF11A, TNFSF11
25neuroma9.9CALCA, TNFRSF11A, TNFSF11
26scrotal carcinoma9.9CALCA, TNFSF11
27lung occult small cell carcinoma9.9CALCA, TNFRSF11A, TNFSF11
28cherubism9.9
29chondrosarcoma9.9
30ameloblastoma9.9
31myositis9.9
32myositis ossificans9.9
33juvenile ossifying fibroma9.9
34bone resorption disease9.8TNFRSF11A, TNFSF11
35gastrointestinal stromal tumor9.7
36focal dermal hypoplasia9.7
37bone fracture9.7
38hydrocephalus9.7
39angiosarcoma9.7
40partial third-nerve palsy9.7
41horner's syndrome9.7
42tooth resorption9.7
43obstructive hydrocephalus9.7
44langerhans-cell histiocytosis9.7
45histiocytosis9.7
46mesenchymal chondrosarcoma9.7
47clear cell chondrosarcoma9.7
48neuropathy9.7
49exophthalmos9.7
50fasciitis9.7

Graphical network of the top 20 diseases related to Aneurysmal Bone Cysts:



Diseases related to aneurysmal bone cysts

Symptoms for Aneurysmal Bone Cysts

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Clinical features from OMIM:

606179

UMLS symptoms related to Aneurysmal Bone Cysts:


pain

Drugs & Therapeutics for Aneurysmal Bone Cysts

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Aneurysmal Bone Cysts

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Aneurysmal Bone Cysts cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Aneurysmal Bone Cysts:
Bone marrow-derived mesenchymal cell transplantation for bone cysts
Embryonic/Adult Cultured Cells Related to Aneurysmal Bone Cysts:
Bone marrow-derived mesenchymal stem cells (family)

Genetic Tests for Aneurysmal Bone Cysts

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Anatomical Context for Aneurysmal Bone Cysts

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MalaCards organs/tissues related to Aneurysmal Bone Cysts:

34
Bone, Bone marrow, Endothelial

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Aneurysmal Bone Cysts:
id TissueAnatomical CompartmentCell Relevance
1 BoneBone MarrowBone Marrow Stromal Cells Potential therapeutic candidate

Animal Models for Aneurysmal Bone Cysts or affiliated genes

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Publications for Aneurysmal Bone Cysts

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Articles related to Aneurysmal Bone Cysts:

(show top 50)    (show all 281)
idTitleAuthorsYear
1
Craniospinal Polyostotic Fibrous Dysplasia, Aneurysmal Bone Cysts, and Chiari Type 1 Malformation Coexistence in a Patient with McCune-Albright Syndrome. (27161212)
2016
2
An endolymphatic sac tumor with imaging features of aneurysmal bone cysts: differential diagnostic considerations. (24881035)
2014
3
USP6-induced neoplasms: the biologic spectrum of aneurysmal bone cyst and nodular fasciitis. (23769422)
2014
4
Clear cell chondrosarcoma with secondary aneurysmal bone cyst changes. (24664395)
2014
5
Aneurysmal bone cysts of the spine: two case reports. (25620988)
2014
6
Denosumab: a potential new and innovative treatment option for aneurysmal bone cysts. (23455951)
2013
7
Giant cell tumor with secondary aneurysmal bone cyst: a unique presentation with an ossified extraosseous soft tissue mass. (23708046)
2013
8
Gastrointestinal stromal tumor of the ampulla of Vater with osteoclastic giant cells, osteoid-like matrix deposition, and aneurysmal bone cyst-like features. (23036260)
2013
9
Chondroblastoma with secondary aneurysmal bone cyst of the hamate: case report. (22284749)
2012
10
Giant pediatric aneurysmal bone cysts of the occipital bone: case report and review of the literature. (21723459)
2011
11
Temporal bone chondroblastoma with secondary aneurysmal bone cyst presenting as an intracranial mass with clinical seizure activity. (21514167)
2011
12
Fibrous dysplasia and aneurysmal bone cyst of the skull base presenting with blindness: a report of a rare locally aggressive example. (21396116)
2011
13
Factors associated with recurrence of primary aneurysmal bone cysts: is argon beam coagulation an effective adjuvant treatment? (22048101)
2011
14
Aneurysmal bone cyst concomitant with fibrous dysplasia in the frontal bone. (20956929)
2010
15
Aneurysmal bone cysts of the jaws: analysis of 17 cases. (20110147)
2010
16
A cherubism with aneurysmal bone cyst. (19386735)
2009
17
Treatment of large recurrent aneurysmal bone cysts of mandible: transosseous intralesional embolization as an adjunct to resection. (19243916)
2009
18
Malignant transformation of aneurysmal bone cysts: a case report. (19187628)
2009
19
Treatment of aneurysmal bone cysts with percutaneous sclerotherapy using polidocanol. A review of 72 cases with long-term follow-up. (16943475)
2006
20
Bone matrix therapy for aneurysmal bone cysts. (16037557)
2005
21
Aneurysmal bone cyst arising from fibrous dysplasia of the frontal bone (2004:2b). (15162799)
2004
22
Classic adamantinoma with osteofibrous dysplasia-like foci and secondary aneurysmal bone cyst. (12574919)
2003
23
Subperiosteal aneurysmal bone cysts: 2 case reports. (14689805)
2003
24
Sclerotherapy in aneurysmal bone cysts in children: a review of 17 cases. (12768252)
2003
25
Treatment of aneurysmal bone cysts with saucerization and bone marrow injection in children. (10413010)
1999
26
Aneurysmal bone cysts of the maxilla: a clinicopathologic review. (9371109)
1997
27
Arterial embolization of aneurysmal bone cysts in children. (8731423)
1996
28
Aneurysmal bone cyst presenting as Horner's syndrome. (7610419)
1995
29
Aneurysmal bone cyst of the maxilla--an association with tooth resorption. (1401102)
1992
30
Fluid levels in aneurysmal bone cysts. (1795415)
1991
31
Aneurysmal bone cysts: imaging findings and embolotherapy. (2750623)
1989
32
Case report 566: Osteoblastoma of sacrum with secondary aneurysmal bone cyst. (2814559)
1989
33
Aneurysmal bone cysts of the jaws: a case study and review of the literature. (3475661)
1987
34
Immunocytochemical markers (endothelial and histiocytic) and ultrastructure of primary aneurysmal bone cysts. (3080364)
1986
35
Aneurysmal bone cysts of the pelvis. (3535735)
1986
36
Concurrent osteoblastoma and aneurysmal bone cyst of the ethmoid sinus: case report. (4053663)
1985
37
Aneurysmal bone cysts in the cranial vault and base of skull. (3966216)
1985
38
Aneurysmal bone cysts of the spine. Report of 17 cases. (4056871)
1985
39
Case report 249. Osteoblastoma with secondary aneurysmal bone cyst of the frontal bone. (6648568)
1983
40
Aneurysmal bone cysts of the spine. (7404221)
1980
41
Aneurysmal bone cysts: a clinicopathological study of 105 cases. (265751)
1977
42
Aneurysmal bone cysts. (1193666)
1975
43
Giant-cell tumors and aneurysmal bone cysts of ribs in childhood. (1117381)
1975
44
Two cases of aneurysmal bone cysts of the jaws. (4634128)
1972
45
Aneurysmal bone cysts penetrating the tibial epiphysis after curettage. (5100168)
1971
46
Aneurysmal bone cysts. Review of twelve cases. (5238600)
1968
47
Giant-cell tumours and aneurysmal bone cysts of the spine. With special reference to the problems related to the removal of a vertebral body. (5846771)
1965
48
ANEURYSMAL BONE CYSTS OF THE MANDIBLE; REPORT OF A CASE. (14199580)
1964
49
ANEURYSMAL BONE CYST OF THE MAXILLA; ASSOCIATION WITH GIANT CELL REPARATIVE GRANULOMA. (14172812)
1964
50
A possible case of multiple aneurysmal bone cysts. (14487445)
1962

Variations for Aneurysmal Bone Cysts

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Expression for genes affiliated with Aneurysmal Bone Cysts

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Search GEO for disease gene expression data for Aneurysmal Bone Cysts.

Pathways for genes affiliated with Aneurysmal Bone Cysts

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GO Terms for genes affiliated with Aneurysmal Bone Cysts

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Cellular components related to Aneurysmal Bone Cysts according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1growth coneGO:00304269.5CDK5, GSK3B, MAPT
2axonGO:00304248.8CALCA, CDK5, GSK3B, MAPT
3plasma membraneGO:00058865.7CDH11, CDK5, GBP1, GSK3B, MAPT, SLCO1A2

Biological processes related to Aneurysmal Bone Cysts according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signalingGO:007184810.4TNFRSF11A, TNFSF11
2positive regulation of fever generation by positive regulation of prostaglandin secretionGO:007181210.4TNFRSF11A, TNFSF11
3TNFSF11-mediated signaling pathwayGO:007184710.3TNFRSF11A, TNFSF11
4osteoclast differentiationGO:003031610.2TNFRSF11A, TNFSF11
5peptidyl-threonine phosphorylationGO:001810710.1CDK5, GSK3B
6mammary gland alveolus developmentGO:006074910.1TNFRSF11A, TNFSF11
7axon extensionGO:00486759.9CDK5, MAPT
8positive regulation of neuron deathGO:19012169.9CDK5, GSK3B
9positive regulation of axon extensionGO:00457739.9GSK3B, MAPT
10sodium-independent organic anion transportGO:00432529.8SLCO1A2, SLCO3A1, SLCO4A1
11monocyte chemotaxisGO:00025489.7CALCA, TNFRSF11A, TNFSF11
12ossificationGO:00015039.7CDH11, TNFRSF11A, TNFSF11
13axonogenesisGO:00074099.3CDK5, GSK3B, MAPT

Molecular functions related to Aneurysmal Bone Cysts according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1tau-protein kinase activityGO:00503219.7CDK5, GSK3B
2sodium-independent organic anion transmembrane transporter activityGO:00153479.5SLCO1A2, SLCO3A1, SLCO4A1
3cytokine bindingGO:00199559.3GBP1, TNFRSF11A

Sources for Aneurysmal Bone Cysts

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet