MCID: ANG054
MIFTS: 49

Angina Pectoris

Categories: Cardiovascular diseases

Aliases & Classifications for Angina Pectoris

MalaCards integrated aliases for Angina Pectoris:

Name: Angina Pectoris 39 38

Classifications:



External Ids:

ICD10 33 I20 I20.1

Summaries for Angina Pectoris

MalaCards based summary : Angina Pectoris is related to heart disease and coronary stenosis. An important gene associated with Angina Pectoris is CRP (C-Reactive Protein), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Covera-HS and Nitroglycerin have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and endothelial, and related phenotypes are cardiovascular system and hematopoietic system

Related Diseases for Angina Pectoris

Diseases related to Angina Pectoris via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 265)
id Related Disease Score Top Affiliating Genes
1 heart disease 31.5 ACE CRP
2 coronary stenosis 30.7 F3 SERPINC1
3 essential thrombocythemia 29.8 F3 SERPINC1 VWF
4 ischemic heart disease 28.7 ACE CRP IL6 SERPINC1 SERPINE1 VWF
5 pericarditis 25.9 ACE CRP F3 KNG1 PLAT SERPINC1
6 myocardial infarction 25.6 ACE CRP F3 FGA IL6 KNG1
7 prinzmetal's variant angina 10.9
8 collagenopathy type 2 alpha 1 10.8 CRP IL6
9 crystal arthropathies 10.8 CRP IL6
10 shoulder impingement syndrome 10.8 CRP IL6
11 brachydactyly-distal symphalangism syndrome 10.8 CRP IL6
12 iron metabolism disease 10.8 ACE CRP
13 epstein-barr virus hepatitis 10.8 CRP IL6
14 x-linked dominant intellectual disability-epilepsy syndrome 10.8 CRP IL6
15 erythema elevatum diutinum 10.7 CRP IL6
16 cataract congenital autosomal dominant 10.7 CRP IL6
17 malignant gastric granular cell tumor 10.7 CRP IL6
18 superior limbic keratoconjunctivitis 10.7 IL6 SERPINC1
19 primary hyperoxaluria 10.7 ACE SERPINC1
20 nodular nonsuppurative panniculitis 10.7 CRP IL6
21 hemangioma of spleen 10.7 CRP IL6
22 central nervous system leiomyosarcoma 10.7 CRP IL6
23 rocky mountain spotted fever 10.7 CRP SERPINC1
24 lung occult large cell carcinoma 10.7 CRP IL6
25 ciliary discoordination, due to random ciliary orientation 10.7 CRP FGA
26 potato nose 10.7 ACE IL6
27 intermediate coronary syndrome 10.7
28 cicatricial lagophthalmos 10.7 CRP IL6
29 ariboflavinosis 10.7 CRP IL6
30 queensland tick typhus 10.6 CRP IL6
31 listeriosis 10.6 ACE VWF
32 luxation of globe 10.6 CRP IL6
33 angular blepharoconjunctivitis 10.6 IL6 SERPINC1
34 indolent myeloma 10.6 IL6 VWF
35 syndactyly, mesoaxial synostotic, with phalangeal reduction 10.5 SERPINC1 SERPINF2
36 collagenous gastritis 10.5 SERPINC1 SERPINF2
37 allergic bronchopulmonary aspergillosis 10.5 CRP IL6
38 islet cell tumor 10.5 ACE CRP IL6
39 sagittal sinus thrombosis 10.5 F3 SERPINC1
40 placental abruption 10.5 ACE CRP IL6
41 fragile x syndrome type 2 10.5 F3 SERPINC1
42 hereditary amyloidosis 10.5 F3 SERPINC1
43 focal dystonia 10.5 ACE CRP IL6
44 acute myocardial infarction 10.5
45 stoll alembik finck syndrome 10.5 SERPINC1 SERPINE1
46 choroiditis 10.5 ACE CRP IL6
47 coronary artery disease 10.5
48 artery disease 10.5
49 benign neonatal seizures 10.5 CRP IL6
50 myiasis 10.5 F3 SERPINC1

Graphical network of the top 20 diseases related to Angina Pectoris:



Diseases related to Angina Pectoris

Symptoms & Phenotypes for Angina Pectoris

MGI Mouse Phenotypes related to Angina Pectoris:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.91 ACE CRP F3 FGA IL6 PLAT
2 hematopoietic system MP:0005397 9.76 ACE F3 FGA IL6 PLAT SERPINC1
3 homeostasis/metabolism MP:0005376 9.65 ACE CRP F3 FGA IL6 PLAT
4 immune system MP:0005387 9.28 F3 FGA IL6 PLAT SERPINC1 SERPINE1

Drugs & Therapeutics for Angina Pectoris

FDA approved drugs:

id Drug Name Active Ingredient(s) 17 Company Approval Date
1
Covera-HS 17 VERAPAMIL HYDROCHLORIDE GD Searle, Alza January 1996

Drugs for Angina Pectoris (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 550)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Nitroglycerin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 55-63-0 4510
2
Methyltestosterone Approved Phase 4,Phase 3,Phase 2 58-18-4 6010
3
Testosterone Approved, Investigational Phase 4,Phase 3,Phase 2 58-22-0 6013
4
Atenolol Approved Phase 4,Phase 3,Phase 2,Phase 1 29122-68-7 2249
5
Nicorandil Approved Phase 4,Phase 2 65141-46-0 47528
6
Pravastatin Approved Phase 4,Phase 3 81093-37-0 54687
7
Amiodarone Approved, Investigational Phase 4 1951-25-3 2157
8
Ranolazine Approved, Investigational Phase 4,Phase 3,Phase 2 142387-99-3, 95635-55-5 56959
9
Simvastatin Approved Phase 4,Phase 2,Phase 3,Phase 1 79902-63-9 54454
10
Amlodipine Approved Phase 4,Phase 3,Phase 2 88150-42-9 2162
11
Bisoprolol Approved Phase 4 66722-44-9 2405
12
Candesartan Approved Phase 4,Phase 3 139481-59-7 2541
13
Diltiazem Approved Phase 4 42399-41-7 39186
14
Ticagrelor Approved Phase 4,Phase 3,Phase 2,Phase 1 274693-27-5 9871419
15
Udenafil Approved, Investigational Phase 4 268203-93-6 6918523
16
Ramipril Approved Phase 4,Phase 3,Early Phase 1 87333-19-5 5362129
17
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2 33069-62-4 36314
18
Everolimus Approved Phase 4,Phase 3,Phase 2 159351-69-6 6442177
19
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2 53123-88-9 5284616 6436030 46835353
20
Aspirin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 50-78-2 2244
21
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
22
Pantoprazole Approved Phase 4,Phase 3 102625-70-7 4679
23
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1 55142-85-3 5472
24
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 772 46507594
25
Chromium Approved Phase 4,Phase 2,Phase 3 7440-47-3 27668
26
Carvedilol Approved, Investigational Phase 4,Phase 1,Phase 2 72956-09-3 2585
27
Amiloride Approved Phase 4,Phase 2,Phase 3 2016-88-8, 2609-46-3 16231
28
Telmisartan Approved, Investigational Phase 4 144701-48-4 65999
29
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
30
Citalopram Approved Phase 4,Phase 1,Phase 2 59729-33-8 2771
31
Colchicine Approved Phase 4,Phase 3 64-86-8 6167 2833
32
Etanercept Approved, Investigational Phase 4 185243-69-0
33
Bivalirudin Approved, Investigational Phase 4,Phase 3,Phase 2 128270-60-0 16129704
34
Tenecteplase Approved Phase 4 191588-94-0
35
Tirofiban Approved Phase 4,Phase 3,Phase 2 144494-65-5 60947
36
Losartan Approved Phase 4 114798-26-4 3961
37
Nitric Oxide Approved Phase 4,Phase 3,Phase 2,Phase 1 10102-43-9 145068
38
Metoprolol Approved, Investigational Phase 4,Early Phase 1 37350-58-6, 51384-51-1 4171
39
Isosorbide Dinitrate Approved Phase 4,Phase 3,Phase 2,Phase 1 87-33-2 6883
40
Adenosine Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 58-61-7 60961
41
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 22916-47-8 4189
42
Pitavastatin Approved Phase 4 147511-69-1, 147526-32-7 6366718 5282452
43
Eptifibatide Approved, Investigational Phase 4,Phase 3,Phase 2 188627-80-7 123610
44
Ethanol Approved Phase 4 64-17-5 702
45
Menthol Approved Phase 4,Phase 3 2216-51-5 16666
46
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
47
Rivaroxaban Approved Phase 4,Phase 3,Phase 2 366789-02-8
48 Molsidomine Approved Phase 4 25717-80-0
49
Nebivolol Approved, Investigational Phase 4,Phase 1 152520-56-4, 99200-09-6, 118457-14-0 71301
50
Erythromycin Approved, Vet_approved Phase 4 114-07-8 12560

Interventional clinical trials:

(show top 50) (show all 1261)

id Name Status NCT ID Phase Drugs
1 Spinal Cord Stimulation (SCS) in Refractory Angina Unknown status NCT00121654 Phase 4
2 Efficacy and Safety Study of Guanxin Shutong Capsule to Treat Chronic Stable Angina Unknown status NCT02280850 Phase 4 Guanxin Shutong Capsule;Placebo Capsule;nitroglycerine
3 Efficacy Study of Atorvastatin to Treat Variant Angina Unknown status NCT00620204 Phase 4 atorvastatin
4 Testosterone Therapy on Angina Threshold and Atheroma in Patients With Chronic Stable Angina Unknown status NCT00131183 Phase 4 Nebido
5 Study to Assess Efficacy of Nicorandil+Atenolol vs Atenolol in Treatment of Chronic Stable Angina. Unknown status NCT01397994 Phase 4 Nicorandil;Atenolol
6 The Effects of Pravastatin and Rosuvastatin on Coronary Plaques in Patients With Stable Angina Pectoris Unknown status NCT01325818 Phase 4 pravastatin, rosuvastatin
7 Safety of Amiodarone and Ranolazine Together in Patients With Angina Unknown status NCT01558830 Phase 4 ranolazine;placebo
8 The Effect of Sarpogrelate and High Dose Statin on the Reduction of Coronary Spasm Unknown status NCT01674686 Phase 4 Sarpogrelate;Atorvastatin
9 A Pilot Study Exploring Efficacy and Safety of Amlodipine in the Stented Angina Patients Unknown status NCT01120327 Phase 4 Placebo;Amlodipine
10 Coronary Angioplasty in Octogenarians With Emergent Coronary Syndromes Unknown status NCT02126202 Phase 4
11 Comparison of Vascular Remodeling Between Different Antianginal Medication Evaluated by Noninvasive ECG-gated Fundus Photographic Evaluation Unknown status NCT01162902 Phase 4 Diltiazem treated group;Bisoprolol treated group;Candesartan treated group
12 Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Stable Angina, NSTEMI and STEMI Undergoing PCI Unknown status NCT02012140 Phase 4 ticagrelor
13 Understanding of Chest Pain in Microvascular Disease Proved by Cardiac Magnetic Resonance Image Unknown status NCT01769482 Phase 4 Udenafil;placebo
14 Statin and Angiotensin-converting Enzyme Inhibitor on Symptoms in Patients With SCAD Unknown status NCT02008786 Phase 4 ramipril;rosuvastatin;placebo
15 Diagnosis and Treatment of ACS in the ED: The Impact of Rapid Bedside cTnI Testing on Outcomes Unknown status NCT00222352 Phase 4
16 Small Coronary Artery Treated by TAXUS Liberté Registry in Japan Unknown status NCT00955214 Phase 4
17 Intensive Statin Therapy in PCI Patient With Acute Coronary Syndrome Unknown status NCT01372839 Phase 4 Atorvastatin;Statin
18 Ranolazine, Ethnicity and the Metabolic Syndrome Unknown status NCT01304095 Phase 4 Ranolazine
19 Optical Coherence Tomography Comparison of Neointimal Coverage Between CRE8 DES and BMS Unknown status NCT01543373 Phase 4
20 Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN) Unknown status NCT01735227 Phase 4 omeprazole;Pantoprazole
21 Efficacy Study of Nicorandil on Neointima Unknown status NCT02328521 Phase 4 Nicorandil;nicorandil placebo
22 Impact of Ticagrelor on the Endothelial Healing Following Drug-eluting Stent Implantation in the Patients With Acute Coronary Syndrome Unknown status NCT02037412 Phase 4 Ticagrelor;Clopidogrel
23 DEDICA (Dose of HEparin During Coronary Angioplasty) Trial Unknown status NCT01694459 Phase 4 Low-dose heparin;Standard dose heparin
24 A Trial to Evaluate Efficacy of Heart-protecting Musk Pill Unknown status NCT01897805 Phase 4 Heart-protecting Musk Pill;Placebo
25 Comparative Phase IV Study: Efficacy And Safety of TiTAN2 Versus COBALT-CHROME Stents- EVIDENCEII Unknown status NCT01918150 Phase 4
26 Ischemia In Hemodialysed Patients: Ivabradine Versus Carvedilol Unknown status NCT01425164 Phase 4 Ivabradine;Carvedilol
27 Effects of Angiotensin II Receptor Blocker Compared With Diuretics in High-risk Hypertensive Patients Unknown status NCT01011660 Phase 4 Amlodipine, Telmisartan, Amiloride Compound , Simvastatin
28 Pravastatin for Acute Myocardial Infarction With Minimally to Mildly Increased Levels of Serum Cholesterol Study Unknown status NCT00688922 Phase 4 Pravastatin
29 Assessment of Coronary Flow Reserve by Doppler Flow WIre in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Differences Between the Loading Dose of Prasugrel and Ticagrelor . Unknown status NCT02032303 Phase 4 Ticagrelor loading;Prasugrel loading
30 Assessment of Coronary Flow Reserve by Doppler Flow Wire in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Differences Between the Loading Dose of Ticagrelor and Clopidogrel Unknown status NCT02032290 Phase 4 ticagrelor loading;Clopidogrel loading
31 Ranolazine for Improving Symptoms of Palpitations Unknown status NCT01495520 Phase 4 Ranolazine;Placebo
32 The Effectiveness and Safety of Butylphthalide Soft Capsules in Secondary Prevention of Ischemic Stroke Trial Unknown status NCT00724724 Phase 4 Butylphthalide Soft Capsules;Aspirin
33 Italian Diffuse/Multivessel Disease ABSORB Prospective Registry: IT-Disappears Unknown status NCT02004730 Phase 4
34 Effects of the Ivabradine on Reduction of Inflammatory Markers in Patients With Acute Coronary Syndrome Unknown status NCT00815100 Phase 4 Ivabradine;Placebo
35 Testosterone for Peripheral Vascular Disease Unknown status NCT00504712 Phase 4 Testosterone;0.9% saline
36 The Canadian Prevention of Renal and Cardiovascular Endpoints Trial Unknown status NCT00231803 Phase 4
37 A Prospective Multicenter Trial Evaluating Helios Biodegradable Polymer SES Safety and Effectiveness in CAD Treatment Unknown status NCT01880879 Phase 4
38 A Morbidity-Mortality and Remodeling Study With Valsartan Unknown status NCT00133328 Phase 4 valsartan
39 DECARD: Study of Escitalopram in the Prevention of Depression in Patients With Acute Coronary Syndrome Unknown status NCT00140257 Phase 4 Escitalopram
40 Effect of Testosterone on Endothelial Function and Microcirculation in Type 2 Diabetic Patients With Hypogonadism Unknown status NCT01084369 Phase 4 Testosterone
41 Effect of Ranolazine on Valvular Disease in Patients With Pacemakers Unknown status NCT01979965 Phase 4 Ranolazine (Active drug);Placebo
42 The Association Between Very Small Embryonic-like Stem Cells and the Prognosis of Coronary Artery Disease Patients Unknown status NCT01633359 Phase 4 Intensive statin;Routine statin
43 Colchicine for Acute Coronary Syndromes Unknown status NCT01906749 Phase 4 Colchicine;Placebo
44 Etanercept Treating Patient With Acute ST Segment Elevated Myocardial Infarction Unknown status NCT01372930 Phase 4 Etanercept;saline
45 Revascularization in Heart Failure Trial – REHEAT 2 Unknown status NCT00388245 Phase 4
46 Cocktail Injection Improves Outcomes of FFR Guided PCI Unknown status NCT02592720 Phase 4 cocktail
47 Intracoronary Cocktail Injection Combined With Thrombus Aspiration in STEMI Patients Treated With Primary Angioplasty Unknown status NCT02592694 Phase 4 cocktail
48 Japanese Primary Prevention Project With Aspirin Unknown status NCT00225849 Phase 4 Aspirin
49 HOPE-2 Study (Heart Outcomes Prevention Evaluation-2 Study) Unknown status NCT00106886 Phase 4 Folic acid, vitamin B6 and B12 or placebo
50 Hypertension Control Based on Home Blood Pressure Unknown status NCT00198562 Phase 4 Amlodipine, Losartan

Search NIH Clinical Center for Angina Pectoris

Genetic Tests for Angina Pectoris

Anatomical Context for Angina Pectoris

MalaCards organs/tissues related to Angina Pectoris:

39
Heart, Testes, Endothelial, Kidney, Bone, Bone Marrow, Spinal Cord

Publications for Angina Pectoris

Articles related to Angina Pectoris:

(show top 50) (show all 826)
id Title Authors Year
1
Prasugrel as opposed to clopidogrel improves endothelial nitric oxide bioavailability and reduces platelet-leukocyte interaction in patients with unstable angina pectoris: A randomized controlled trial. ( 28709700 )
2017
2
Moderate-dose atorvastatin improves arterial endothelial function in patients with angina pectoris and normal coronary angiogram: a pilot study. ( 28721151 )
2017
3
Evaluation of local carotid stiffness and inflammatory biomarkers in stable angina pectoris. ( 28798782 )
2017
4
Unstable Angina Pectoris in a 22-year-old Female Patient. ( 28090005 )
2017
5
Practice of Comparative Effectiveness Research to Identify Treatment Characteristics of Similar Chinese Patent Medicine for Angina Pectoris. ( 28894471 )
2017
6
Efficacy of spinal cord stimulation as an adjunct therapy for chronic refractory angina pectoris. ( 27836302 )
2017
7
How Efficacious is Danshen (Salvia miltiorrhiza) Dripping Pill in Treating Angina Pectoris? Evidence Assessment for Meta-Analysis of Randomized Controlled Trials. ( 28650203 )
2017
8
High Resting Heart Rate and High BMI Predicted Severe Coronary Atherosclerosis Burden in Patients With Stable Angina Pectoris by SYNTAX Score. ( 28635302 )
2017
9
Metabolomic Evaluation of the Consequences of Plasma Cystathionine Elevation in Adults with Stable Angina Pectoris. ( 28794210 )
2017
10
Chronic refractory angina pectoris: recent progress and remaining challenges. ( 28903477 )
2017
11
Coronary microvascular dysfunction is not associated with a history of reproductive risk factors in women with angina pectoris-An iPOWER substudy. ( 28807722 )
2017
12
Relationship of mean platelet volume to lymphocyte ratio and coronary collateral circulation in patients with stable angina pectoris. ( 28678144 )
2017
13
Panax notoginseng Preparations for Unstable Angina Pectoris: A Systematic Review and Meta-Analysis. ( 28634988 )
2017
14
Serum Uric Acid Could Differentiate Acute Myocardial Infarction and Unstable Angina Pectoris in Hyperuricemic Acute Coronary Syndrome Patients. ( 28790542 )
2017
15
Research of Medical Expenditure among Inpatients with Unstable Angina Pectoris in a Single Center. ( 28639566 )
2017
16
A Successfully Treated Case of Gastrointestinal Stromal Tumor Causing Severe Anemia and Localized Peritonitis Showing Angina Pectoris Resulting in Watershed Cerebral Infarction. ( 28912818 )
2017
17
Statins in Stable Angina Pectoris. ( 28847306 )
2017
18
Microfluidic assay of circulating endothelial cells in coronary artery disease patients with angina pectoris. ( 28704506 )
2017
19
Serial 3-Vessel Optical Coherence Tomography and Intravascular Ultrasound Analysis of Changing Morphologies Associated With Lesion Progression in Patients With Stable Angina Pectoris. ( 28893795 )
2017
20
Ventricular repolarization alterations in women with angina pectoris and suspected coronary microvascular dysfunction. ( 28939174 )
2017
21
The value of peripheral blood eosinophil count in predicting in-stent restenosis in patients with stable angina pectoris undergoing drug eluting stenting. ( 28672766 )
2017
22
SYNTAX Score and Pre- and Poststent Optical Coherence Tomography Findings in the Left Anterior Descending Coronary Artery in Patients With Stable Angina Pectoris. ( 28750824 )
2017
23
Diagnostic and prognostic value of a careful symptom evaluation and high sensitive troponin in patients with suspected stable angina pectoris without prior cardiovascular disease. ( 28031149 )
2016
24
Spinal Cord Stimulation for Refractory Angina Pectoris: A Systematic Review and Meta-analysis. ( 27875377 )
2016
25
Salvianolate injection in the treatment of unstable angina pectoris: A systematic review and meta-analysis. ( 28002341 )
2016
26
In vivo assessment of vasa vasorum neovascularization using intravascular ultrasound: A comparison between acute coronary syndrome and stable angina pectoris. ( 27793409 )
2016
27
Correlation of Angina Pectoris and Perfusion Decrease by Collateral Circulation in Single-Vessel Coronary Chronic Total Occlusion Using Myocardial Perfusion Single-Photon Emission Computed Tomography. ( 26941860 )
2016
28
Monocyte to HDL ratio in prediction of BMS restenosis in subjects with stable and unstable angina pectoris. ( 27415579 )
2016
29
The Impact of Remote Ischemic Preconditioning on Arterial Stiffness and Heart Rate Variability in Patients with Angina Pectoris. ( 27348009 )
2016
30
Treatment of Angina Pectoris Associated with Coronary Microvascular Dysfunction. ( 27358172 )
2016
31
Anti-Anginal and Metabolic Effects of Carvedilol and Atenolol in Patients with Stable Angina Pectoris: A Prospective, Randomized, Parallel, Open-Label Study. ( 27021556 )
2016
32
The Time Course of Markers of Neutrophil Extracellular Traps in Patients Undergoing Revascularisation for Acute Myocardial Infarction or Stable Angina Pectoris. ( 28074081 )
2016
33
A Destabilized Case of Stable Effort Angina Pectoris Induced by Low-dose Adenosine Triphosphate. ( 27853071 )
2016
34
Idiopathic hypereosinophilic syndrome presenting as angina pectoris: A case report. ( 27521535 )
2016
35
Revascularization with percutaneous coronary intervention does not affect androgen status in males with chronic stable angina pectoris. ( 27027684 )
2016
36
WITHDRAWN: Puerarin injection for unstable angina pectoris. ( 27136749 )
2016
37
Relation of Angina Pectoris to Outcomes, Quality of Life, and Response to Exercise Training in Patients With Chronic Heart Failure (from HF-ACTION). ( 27561194 )
2016
38
Cardiac shockwave therapy in patients with chronic refractory angina pectoris. ( 26936156 )
2016
39
Muscle Oxygen Dynamics During Cycling Exercise in Angina Pectoris Patients. ( 27526156 )
2016
40
Efficacy Profile of Ivabradine in Patients with Heart Failure plus Angina Pectoris. ( 27614723 )
2016
41
Percutaneous Coronary Intervention Is More Beneficial Than Optimal Medical Therapy in Elderly Patients with Angina Pectoris. ( 26847290 )
2016
42
The. Thoma Ionescu - Victor Gomoiu Procedure: Cervicothoracic Sympathectomy for Angina Pectoris. The First Surgical Attempt to Treat the Coronary Heart Disease. ( 27544937 )
2016
43
Changes in coronary plaque morphology in patients with acute coronary syndrome versus stable angina pectoris after initiation of statin therapy. ( 27468140 )
2016
44
Narrowing of the Coronary Sinus: A Device-Based Therapy for Persistent Angina Pectoris. ( 26886464 )
2016
45
Aspiration Thrombectomy and Drug-Eluting Stent Implantation Decrease the Occurrence of Angina Pectoris One Year After Acute Myocardial Infarction. ( 27124029 )
2016
46
Danshen injection as adjuvant treatment for unstable angina pectoris: A systematic review and meta-analysis. ( 27921196 )
2016
47
Evaluation of extracorporeal shock wave therapy for refractory angina pectoris with quantitative analysis using cardiac magnetic resonance imaging: aA short communication. ( 27059621 )
2016
48
Effectiveness of Ivabradine in Treating Stable Angina Pectoris. ( 27057864 )
2016
49
Coronary microvascular function and myocardial fibrosis in women with angina pectoris and no obstructive coronary artery disease: the iPOWER study. ( 27809867 )
2016
50
TCT-73 Serial Three-Vessel Optical Coherence Tomography and Intravascular Ultrasound Analysis of Changing Morphologies Associated of Plaque Progression in Patients With Stable Angina Pectoris. ( 27970125 )
2016

Variations for Angina Pectoris

Expression for Angina Pectoris

LifeMap Discovery
Genes differentially expressed in tissues of Angina Pectoris patients vs. healthy controls: 35
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1 EGR3 early growth response 3 Blood + 4.04 0.001
Search GEO for disease gene expression data for Angina Pectoris.

Pathways for Angina Pectoris

Pathways related to Angina Pectoris according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.84 F3 FGA KNG1 PLAT SERPINC1 SERPINE1
2
Show member pathways
12.5 F3 FGA KNG1 SERPINC1
3
Show member pathways
11.76 F3 FGA KNG1 PLAT SERPINC1 SERPINE1
4 11.61 IL6 PLAT SERPINE1
5 11.54 F3 IL6 SERPINE1
6 11.37 F3 FGA KNG1 PLAT SERPINC1 SERPINE1
7 11.18 IL6 KNG1 PLAT
8 10.87 ACE PLAT
9 10.71 CRP IL6
10 10.55 PLAT SERPINE1 SERPINF2

GO Terms for Angina Pectoris

Cellular components related to Angina Pectoris according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.96 ACE CRP F3 FGA KNG1 PLAT
2 cell surface GO:0009986 9.78 F3 FGA PLAT SERPINF2
3 endoplasmic reticulum lumen GO:0005788 9.71 FGA IL6 KNG1 SERPINC1
4 blood microparticle GO:0072562 9.67 FGA KNG1 SERPINC1 SERPINF2
5 extracellular space GO:0005615 9.65 ACE CRP F3 FGA IL6 KNG1
6 extracellular matrix GO:0031012 9.62 F3 PLAT SERPINE1 VWF
7 platelet alpha granule lumen GO:0031093 9.55 FGA KNG1 SERPINE1 SERPINF2 VWF
8 platelet alpha granule GO:0031091 9.46 FGA VWF
9 fibrinogen complex GO:0005577 9.43 FGA SERPINF2
10 extracellular region GO:0005576 9.36 ACE CRP F3 FGA IL6 KNG1

Biological processes related to Angina Pectoris according to GeneCards Suite gene sharing:

(show all 21)
id Name GO ID Score Top Affiliating Genes
1 post-translational protein modification GO:0043687 9.84 FGA IL6 KNG1 SERPINC1
2 extracellular matrix organization GO:0030198 9.77 FGA SERPINE1 VWF
3 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.77 FGA IL6 SERPINF2
4 platelet activation GO:0030168 9.73 FGA IL6 VWF
5 cellular protein metabolic process GO:0044267 9.73 FGA IL6 KNG1 SERPINC1
6 negative regulation of endopeptidase activity GO:0010951 9.67 KNG1 SERPINC1 SERPINE1 SERPINF2
7 platelet degranulation GO:0002576 9.65 FGA KNG1 SERPINE1 SERPINF2 VWF
8 negative regulation of peptidase activity GO:0010466 9.62 KNG1 SERPINC1 SERPINE1 SERPINF2
9 negative regulation of endothelial cell apoptotic process GO:2000352 9.58 FGA SERPINE1
10 negative regulation of proteolysis GO:0045861 9.58 KNG1 PLAT
11 acute-phase response GO:0006953 9.58 CRP IL6 SERPINF2
12 blood coagulation, intrinsic pathway GO:0007597 9.57 KNG1 VWF
13 negative regulation of blood coagulation GO:0030195 9.55 KNG1 SERPINE1
14 plasminogen activation GO:0031639 9.52 FGA PLAT
15 neutrophil mediated immunity GO:0002446 9.51 ACE IL6
16 negative regulation of fibrinolysis GO:0051918 9.49 SERPINE1 SERPINF2
17 negative regulation of lipid storage GO:0010888 9.48 CRP IL6
18 negative regulation of plasminogen activation GO:0010757 9.46 SERPINE1 SERPINF2
19 fibrinolysis GO:0042730 9.46 FGA PLAT SERPINE1 SERPINF2
20 blood coagulation GO:0007596 9.43 F3 FGA KNG1 PLAT SERPINC1 VWF
21 hemostasis GO:0007599 9.02 F3 FGA KNG1 SERPINC1 VWF

Molecular functions related to Angina Pectoris according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 receptor binding GO:0005102 9.55 FGA IL6 KNG1 PLAT SERPINE1
2 serine-type endopeptidase inhibitor activity GO:0004867 9.43 SERPINC1 SERPINE1 SERPINF2
3 peptidase inhibitor activity GO:0030414 9.26 KNG1 SERPINC1 SERPINE1 SERPINF2
4 protease binding GO:0002020 9.02 F3 SERPINC1 SERPINE1 SERPINF2 VWF

Sources for Angina Pectoris

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
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