MCID: ANG054
MIFTS: 50

Angina Pectoris malady

Categories: Cardiovascular diseases

Aliases & Classifications for Angina Pectoris

Aliases & Descriptions for Angina Pectoris:

Name: Angina Pectoris 39 38

Classifications:



External Ids:

ICD10 33 I20

Summaries for Angina Pectoris

MalaCards based summary : Angina Pectoris is related to essential thrombocythemia and myocardial infarction. An important gene associated with Angina Pectoris is CRP (C-Reactive Protein), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Covera-HS and Nitroglycerin have been mentioned in the context of this disorder. Affiliated tissues include heart, spinal cord and testes, and related phenotypes are cardiovascular system and hematopoietic system

Wikipedia : 71 Angina pectoris, commonly known as angina, is the sensation of chest pain, pressure, or squeezing, often... more...

Related Diseases for Angina Pectoris

Diseases related to Angina Pectoris via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 233)
id Related Disease Score Top Affiliating Genes
1 essential thrombocythemia 29.7 F3 SERPINC1 VWF
2 myocardial infarction 29.0 ACE CRP F3 FGA IL6 KNG1
3 pericarditis 28.2 ACE CRP F3 KNG1 PLAT SERPINC1
4 prinzmetal's variant angina 11.7
5 intermediate coronary syndrome 10.7
6 acute myocardial infarction 10.5
7 artery disease 10.5
8 coronary artery disease 10.5
9 endotheliitis 10.4
10 heart disease 10.3
11 ischemia 10.3
12 chronic angina 10.3
13 coloboma of iris 10.3 CRP IL6
14 cutaneous sclerosis 10.3 CRP IL6
15 iron metabolism disease 10.3 ACE CRP
16 shoulder impingement syndrome 10.3 CRP IL6
17 neutrophilia, hereditary 10.3 CRP IL6
18 swine influenza 10.3 CRP IL6
19 carbohydrate metabolic disorder 10.3 ACE SERPINC1
20 cardiac tuberculosis 10.3 CRP IL6
21 cataract, total congenital 10.3 CRP IL6
22 laryngotracheoesophageal cleft type 2 10.3 CRP IL6
23 citrulline transport defect 10.3 CRP FGA
24 degenerative disc disease 10.3 IL6 VWF
25 cataract 10.3 CRP SERPINC1
26 gastric lymphoma 10.2 CRP IL6
27 listeriosis 10.2 ACE VWF
28 human immunodeficiency virus infectious disease 10.2 CRP IL6
29 preaxial polydactyly of fingers 10.2 ACE IL6
30 coronary stenosis 10.2
31 oropharyngeal anthrax 10.2 CRP SERPINC1
32 miller-dieker lissencephaly syndrome 10.2 SERPINC1 SERPINF2
33 joint disorders 10.2 ACE CRP IL6
34 toxic myocarditis 10.2 ACE CRP IL6
35 focal dystonia 10.2 ACE CRP IL6
36 choroiditis 10.2 ACE CRP IL6
37 stt3a-cdg and stt3b-cdg 10.2 SERPINC1 SERPINE1
38 limb ischemia 10.2 ACE CRP IL6
39 familial nephrotic syndrome 10.2 ACE CRP IL6
40 sertoli cell tumor 10.2 F3 SERPINC1
41 diabetic encephalopathy 10.2 ACE CRP IL6
42 freiberg's disease 10.2 F3 SERPINC1
43 coloboma of optic papilla 10.2 SERPINC1 SERPINF2
44 hereditary endotheliopathy, retinopathy, nephropathy, and stroke 10.2 F3 SERPINC1
45 acute chest syndrome 10.2 ACE CRP IL6
46 calcinosis 10.2 ACE CRP IL6
47 chronic myocardial ischemia 10.2 ACE CRP IL6
48 pancreatic ductal carcinoma 10.2 F3 SERPINC1
49 atherosclerosis 10.2
50 pyelonephritis 10.2 ACE CRP SERPINC1

Graphical network of the top 20 diseases related to Angina Pectoris:



Diseases related to Angina Pectoris

Symptoms & Phenotypes for Angina Pectoris

MGI Mouse Phenotypes related to Angina Pectoris:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.91 ACE CRP F3 FGA IL6 PLAT
2 hematopoietic system MP:0005397 9.76 ACE F3 FGA IL6 PLAT SERPINC1
3 homeostasis/metabolism MP:0005376 9.65 ACE CRP F3 FGA IL6 PLAT
4 immune system MP:0005387 9.28 SERPINE1 VWF ACE CRP F3 FGA

Drugs & Therapeutics for Angina Pectoris

FDA approved drugs:

id Drug Name Active Ingredient(s) 17 Company Approval Date
1
Covera-HS 17 VERAPAMIL HYDROCHLORIDE GD Searle, Alza Approved January 1996

Drugs for Angina Pectoris (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 545)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Nitroglycerin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 55-63-0 4510
2
Methyltestosterone Approved Phase 4,Phase 3,Phase 2 58-18-4 6010
3
Testosterone Approved, Investigational Phase 4,Phase 3,Phase 2 58-22-0 6013
4
Atenolol Approved Phase 4,Phase 3,Phase 2,Phase 1 29122-68-7 2249
5
Nicorandil Approved Phase 4,Phase 2 65141-46-0 47528
6
Pravastatin Approved Phase 4,Phase 3 81093-37-0 54687
7
Amiodarone Approved, Investigational Phase 4 1951-25-3 2157
8
Ranolazine Approved, Investigational Phase 4,Phase 3,Phase 2 142387-99-3, 95635-55-5 56959
9
Simvastatin Approved Phase 4,Phase 2,Phase 3,Phase 1 79902-63-9 54454
10
Amlodipine Approved Phase 4,Phase 3,Phase 2 88150-42-9 2162
11
Bisoprolol Approved Phase 4 66722-44-9 2405
12
Candesartan Approved Phase 4,Phase 3 139481-59-7 2541
13
Diltiazem Approved Phase 4 42399-41-7 39186
14
Ticagrelor Approved Phase 4,Phase 3,Phase 2,Phase 1 274693-27-5 9871419
15
Udenafil Approved, Investigational Phase 4 268203-93-6 6918523
16
Ramipril Approved Phase 4,Phase 3,Early Phase 1 87333-19-5 5362129
17
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2 33069-62-4 36314
18
Everolimus Approved Phase 4,Phase 3,Phase 2 159351-69-6 6442177
19
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2 53123-88-9 5284616 6436030 46835353
20
Aspirin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 50-78-2 2244
21
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
22
Pantoprazole Approved Phase 4,Phase 3 102625-70-7 4679
23
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1 55142-85-3 5472
24
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 772 46507594
25
Carvedilol Approved, Investigational Phase 4,Phase 1,Phase 2 72956-09-3 2585
26
Amiloride Approved Phase 4,Phase 2,Phase 3 2016-88-8, 2609-46-3 16231
27
Telmisartan Approved, Investigational Phase 4 144701-48-4 65999
28
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
29
Citalopram Approved Phase 4,Phase 1,Phase 2 59729-33-8 2771
30
Colchicine Approved Phase 4,Phase 3 64-86-8 6167 2833
31
Etanercept Approved, Investigational Phase 4 185243-69-0
32
Losartan Approved Phase 4 114798-26-4 3961
33
Nitric Oxide Approved Phase 4,Phase 3,Phase 2,Phase 1 10102-43-9 145068
34
Metoprolol Approved, Investigational Phase 4,Early Phase 1 37350-58-6, 51384-51-1 4171
35
Isosorbide Dinitrate Approved Phase 4,Phase 3,Phase 1,Phase 2 87-33-2 6883
36
Bivalirudin Approved, Investigational Phase 4,Phase 3,Phase 2 128270-60-0 16129704
37
Adenosine Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 58-61-7 60961
38
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 22916-47-8 4189
39
Pitavastatin Approved Phase 4 147511-69-1, 147526-32-7 6366718 5282452
40
Eptifibatide Approved, Investigational Phase 4,Phase 3,Phase 2 188627-80-7 123610
41
Ethanol Approved Phase 4 64-17-5 702
42
Tirofiban Approved Phase 4,Phase 3,Phase 2 144494-65-5 60947
43
Menthol Approved Phase 4,Phase 3 2216-51-5 16666
44
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
45
Rivaroxaban Approved Phase 4,Phase 3,Phase 2 366789-02-8
46 Molsidomine Approved Phase 4 25717-80-0
47
Nebivolol Approved, Investigational Phase 4,Phase 1 152520-56-4, 99200-09-6, 118457-14-0 71301
48
Erythromycin Approved, Vet_approved Phase 4 114-07-8 12560
49
Metformin Approved Phase 4 657-24-9 14219 4091
50
Verapamil Approved Phase 4,Phase 2 52-53-9 2520

Interventional clinical trials:

(show top 50) (show all 1226)
id Name Status NCT ID Phase
1 Spinal Cord Stimulation (SCS) in Refractory Angina Unknown status NCT00121654 Phase 4
2 Efficacy and Safety Study of Guanxin Shutong Capsule to Treat Chronic Stable Angina Unknown status NCT02280850 Phase 4
3 Efficacy Study of Atorvastatin to Treat Variant Angina Unknown status NCT00620204 Phase 4
4 Testosterone Therapy on Angina Threshold and Atheroma in Patients With Chronic Stable Angina Unknown status NCT00131183 Phase 4
5 Study to Assess Efficacy of Nicorandil+Atenolol vs Atenolol in Treatment of Chronic Stable Angina. Unknown status NCT01397994 Phase 4
6 The Effects of Pravastatin and Rosuvastatin on Coronary Plaques in Patients With Stable Angina Pectoris Unknown status NCT01325818 Phase 4
7 Safety of Amiodarone and Ranolazine Together in Patients With Angina Unknown status NCT01558830 Phase 4
8 The Effect of Sarpogrelate and High Dose Statin on the Reduction of Coronary Spasm Unknown status NCT01674686 Phase 4
9 A Pilot Study Exploring Efficacy and Safety of Amlodipine in the Stented Angina Patients Unknown status NCT01120327 Phase 4
10 Coronary Angioplasty in Octogenarians With Emergent Coronary Syndromes Unknown status NCT02126202 Phase 4
11 Comparison of Vascular Remodeling Between Different Antianginal Medication Evaluated by Noninvasive ECG-gated Fundus Photographic Evaluation Unknown status NCT01162902 Phase 4
12 Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Stable Angina, NSTEMI and STEMI Undergoing PCI Unknown status NCT02012140 Phase 4
13 Understanding of Chest Pain in Microvascular Disease Proved by Cardiac Magnetic Resonance Image Unknown status NCT01769482 Phase 4
14 Statin and Angiotensin-converting Enzyme Inhibitor on Symptoms in Patients With SCAD Unknown status NCT02008786 Phase 4
15 Diagnosis and Treatment of ACS in the ED: The Impact of Rapid Bedside cTnI Testing on Outcomes Unknown status NCT00222352 Phase 4
16 Small Coronary Artery Treated by TAXUS Liberté Registry in Japan Unknown status NCT00955214 Phase 4
17 Intensive Statin Therapy in PCI Patient With Acute Coronary Syndrome Unknown status NCT01372839 Phase 4
18 Ranolazine, Ethnicity and the Metabolic Syndrome Unknown status NCT01304095 Phase 4
19 Optical Coherence Tomography Comparison of Neointimal Coverage Between CRE8 DES and BMS Unknown status NCT01543373 Phase 4
20 Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN) Unknown status NCT01735227 Phase 4
21 Efficacy Study of Nicorandil on Neointima Unknown status NCT02328521 Phase 4
22 Impact of Ticagrelor on the Endothelial Healing Following Drug-eluting Stent Implantation in the Patients With Acute Coronary Syndrome Unknown status NCT02037412 Phase 4
23 DEDICA (Dose of HEparin During Coronary Angioplasty) Trial Unknown status NCT01694459 Phase 4
24 A Trial to Evaluate Efficacy of Heart-protecting Musk Pill Unknown status NCT01897805 Phase 4
25 Comparative Phase IV Study: Efficacy And Safety of TiTAN2 Versus COBALT-CHROME Stents- EVIDENCEII Unknown status NCT01918150 Phase 4
26 Ischemia In Hemodialysed Patients: Ivabradine Versus Carvedilol Unknown status NCT01425164 Phase 4
27 Effects of Angiotensin II Receptor Blocker Compared With Diuretics in High-risk Hypertensive Patients Unknown status NCT01011660 Phase 4
28 Pravastatin for Acute Myocardial Infarction With Minimally to Mildly Increased Levels of Serum Cholesterol Study Unknown status NCT00688922 Phase 4
29 Assessment of Coronary Flow Reserve by Doppler Flow WIre in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Differences Between the Loading Dose of Prasugrel and Ticagrelor . Unknown status NCT02032303 Phase 4
30 Assessment of Coronary Flow Reserve by Doppler Flow Wire in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Differences Between the Loading Dose of Ticagrelor and Clopidogrel Unknown status NCT02032290 Phase 4
31 Ranolazine for Improving Symptoms of Palpitations Unknown status NCT01495520 Phase 4
32 The Effectiveness and Safety of Butylphthalide Soft Capsules in Secondary Prevention of Ischemic Stroke Trial Unknown status NCT00724724 Phase 4
33 Italian Diffuse/Multivessel Disease ABSORB Prospective Registry: IT-Disappears Unknown status NCT02004730 Phase 4
34 Effects of the Ivabradine on Reduction of Inflammatory Markers in Patients With Acute Coronary Syndrome Unknown status NCT00815100 Phase 4
35 Testosterone for Peripheral Vascular Disease Unknown status NCT00504712 Phase 4
36 The Canadian Prevention of Renal and Cardiovascular Endpoints Trial Unknown status NCT00231803 Phase 4
37 A Prospective Multicenter Trial Evaluating Helios Biodegradable Polymer SES Safety and Effectiveness in CAD Treatment Unknown status NCT01880879 Phase 4
38 A Morbidity-Mortality and Remodeling Study With Valsartan Unknown status NCT00133328 Phase 4
39 DECARD: Study of Escitalopram in the Prevention of Depression in Patients With Acute Coronary Syndrome Unknown status NCT00140257 Phase 4
40 Effect of Testosterone on Endothelial Function and Microcirculation in Type 2 Diabetic Patients With Hypogonadism Unknown status NCT01084369 Phase 4
41 Effect of Ranolazine on Valvular Disease in Patients With Pacemakers Unknown status NCT01979965 Phase 4
42 The Association Between Very Small Embryonic-like Stem Cells and the Prognosis of Coronary Artery Disease Patients Unknown status NCT01633359 Phase 4
43 Colchicine for Acute Coronary Syndromes Unknown status NCT01906749 Phase 4
44 Etanercept Treating Patient With Acute ST Segment Elevated Myocardial Infarction Unknown status NCT01372930 Phase 4
45 Revascularization in Heart Failure Trial – REHEAT 2 Unknown status NCT00388245 Phase 4
46 Japanese Primary Prevention Project With Aspirin Unknown status NCT00225849 Phase 4
47 HOPE-2 Study (Heart Outcomes Prevention Evaluation-2 Study) Unknown status NCT00106886 Phase 4
48 Hypertension Control Based on Home Blood Pressure Unknown status NCT00198562 Phase 4
49 Effects of Levothyroxine Supplementation in Patients With Systolic Heart Failure and Subclinical Hypothyroidism Unknown status NCT02316743 Phase 4
50 Comparison of Carvedilol and Atenolol on Anti-anginal and Metabolic Effects in Patients With Stable Angina Pectoris Completed NCT02547597 Phase 4

Search NIH Clinical Center for Angina Pectoris

Genetic Tests for Angina Pectoris

Anatomical Context for Angina Pectoris

MalaCards organs/tissues related to Angina Pectoris:

39
Heart, Spinal Cord, Testes, Endothelial, Monocytes, Neutrophil, Brain

Publications for Angina Pectoris

Articles related to Angina Pectoris:

(show top 50) (show all 805)
id Title Authors Year
1
Unstable Angina Pectoris in a 22-year-old Female Patient. ( 28090005 )
2017
2
Efficacy of spinal cord stimulation as an adjunct therapy for chronic refractory angina pectoris. ( 27836302 )
2017
3
The Role of Ivabradine in the Management of Angina Pectoris. ( 27475447 )
2016
4
Manual Thrombus Aspiration and the Improved Survival of Patients With Unstable Angina Pectoris Treated With Percutaneous Coronary Intervention (30 Months Follow-Up). ( 26937936 )
2016
5
Salvianolate injection in the treatment of unstable angina pectoris: A systematic review and meta-analysis. ( 28002341 )
2016
6
A literature review to evaluate the economic value of ranolazine for the symptomatic treatment of chronic angina pectoris. ( 26994453 )
2016
7
Methylenetetrahydrofolate Dehydrogenase 1 Polymorphisms Modify the Associations of Plasma Glycine and Serine With Risk of Acute Myocardial Infarction in Patients With Stable Angina Pectoris in WENBIT (Western Norway B Vitamin Intervention Trial). ( 27872106 )
2016
8
Propranolol for Angina Pectoris. ( 27828838 )
2016
9
Treatment of Angina Pectoris Associated with Coronary Microvascular Dysfunction. ( 27358172 )
2016
10
Anti-Anginal and Metabolic Effects of Carvedilol and Atenolol in Patients with Stable Angina Pectoris: A Prospective, Randomized, Parallel, Open-Label Study. ( 27021556 )
2016
11
Percutaneous coronary intervention for poor coronary microcirculation reperfusion of patients with stable angina pectoris. ( 27655490 )
2016
12
Narrowing of the Coronary Sinus: A Device-Based Therapy for Persistent Angina Pectoris. ( 26886464 )
2016
13
Monocyte to HDL ratio in prediction of BMS restenosis in subjects with stable and unstable angina pectoris. ( 27415579 )
2016
14
Effectiveness of Ivabradine in Treating Stable Angina Pectoris. ( 27057864 )
2016
15
Diagnostic and prognostic value of a careful symptom evaluation and high sensitive troponin in patients with suspected stable angina pectoris without prior cardiovascular disease. ( 28031149 )
2016
16
Percutaneous Coronary Intervention Is More Beneficial Than Optimal Medical Therapy in Elderly Patients with Angina Pectoris. ( 26847290 )
2016
17
The Impact of Remote Ischemic Preconditioning on Arterial Stiffness and Heart Rate Variability in Patients with Angina Pectoris. ( 27348009 )
2016
18
The Time Course of Markers of Neutrophil Extracellular Traps in Patients Undergoing Revascularisation for Acute Myocardial Infarction or Stable Angina Pectoris. ( 28074081 )
2016
19
Low Volume Aerobic Training Heightens Muscle Deoxygenation in Early Post-Angina Pectoris Patients. ( 27526151 )
2016
20
A Destabilized Case of Stable Effort Angina Pectoris Induced by Low-dose Adenosine Triphosphate. ( 27853071 )
2016
21
Coronary microvascular function and myocardial fibrosis in women with angina pectoris and no obstructive coronary artery disease: the iPOWER study. ( 27809867 )
2016
22
TCT-73 Serial Three-Vessel Optical Coherence Tomography and Intravascular Ultrasound Analysis of Changing Morphologies Associated of Plaque Progression in Patients With Stable Angina Pectoris. ( 27970125 )
2016
23
The. Thoma Ionescu - Victor Gomoiu Procedure: Cervicothoracic Sympathectomy for Angina Pectoris. The First Surgical Attempt to Treat the Coronary Heart Disease. ( 27544937 )
2016
24
Efficacy Profile of Ivabradine in Patients with Heart Failure plus Angina Pectoris. ( 27614723 )
2016
25
Evaluation of extracorporeal shock wave therapy for refractory angina pectoris with quantitative analysis using cardiac magnetic resonance imaging: aA short communication. ( 27059621 )
2016
26
WITHDRAWN: Puerarin injection for unstable angina pectoris. ( 27136749 )
2016
27
Idiopathic hypereosinophilic syndrome presenting as angina pectoris: A case report. ( 27521535 )
2016
28
Danshenchuanxiongqin injection in the treatment of unstable angina pectoris: a systematic review and Meta-analysis. ( 27400467 )
2016
29
Re: Angina pectoris revisited; exertional angina preceded Martin Luther's last stretch of a final journey; European Heart Journal (2016) 37, 206-216. ( 27609104 )
2016
30
Danshen injection as adjuvant treatment for unstable angina pectoris: A systematic review and meta-analysis. ( 27921196 )
2016
31
Relationship of coronary collateral circulation with eosinophils in patients with unstable angina pectoris. ( 26889082 )
2016
32
Long-Term Preservation of Left Ventricular Systolic Function in Patients With Refractory Angina Pectoris and Inducible Myocardial Ischemia on Optimal Medical Therapy. ( 27055755 )
2016
33
Endothelial immunomediated reactivity in acute cardiac ischaemia: Role of endothelin 1, interleukin 8 and NT-proBNP in patients affected by unstable angina pectoris. ( 26684625 )
2016
34
Dental Calculus Links Statistically to Angina Pectoris: 26-Year Observational Study. ( 27336307 )
2016
35
Alternative complement pathway activation during invasive coronary procedures in acute myocardial infarction and stable angina pectoris. ( 27794429 )
2016
36
TCT-496 Differences in quantitative coronary angiographic (QCA) characteristics of coronary artery disease between Human Immunodeficiency Virus (HIV) patients presenting with acute coronary syndrome (ACS) and stable angina pectoris (SAP) undergoing percutaneous coronary intervention (PCI). ( 27969855 )
2016
37
Spinal Cord Stimulation for Refractory Angina Pectoris: A Systematic Review and Meta-analysis. ( 27875377 )
2016
38
Cardiac shockwave therapy in patients with chronic refractory angina pectoris. ( 26936156 )
2016
39
Severe angina pectoris in asthma attack: a case report. ( 27504177 )
2016
40
N-Terminal Pro-B-Type Natriuretic Peptide Levels Inversely Correlated With Heart Rate Variability in Patients With Unstable Angina Pectoris. ( 27170473 )
2016
41
Association between Body Mass Index, Asymmetric Dimethylarginine and Risk of Cardiovascular Events and Mortality in Norwegian Patients with Suspected Stable Angina Pectoris. ( 27003294 )
2016
42
Correlation of Angina Pectoris and Perfusion Decrease by Collateral Circulation in Single-Vessel Coronary Chronic Total Occlusion Using Myocardial Perfusion Single-Photon Emission Computed Tomography. ( 26941860 )
2016
43
In vivo assessment of vasa vasorum neovascularization using intravascular ultrasound: A comparison between acute coronary syndrome and stable angina pectoris. ( 27793409 )
2016
44
Changes in coronary plaque morphology in patients with acute coronary syndrome versus stable angina pectoris after initiation of statin therapy. ( 27468140 )
2016
45
TCT-189 Comparison of 5-year Clinical Outcomes between Stabilized Acute Myocardial Infarction Patients following Percutaneous Coronary Intervention and the Patients with Angina Pectoris. ( 27970359 )
2016
46
Aspiration Thrombectomy and Drug-Eluting Stent Implantation Decrease the Occurrence of Angina Pectoris One Year After Acute Myocardial Infarction. ( 27124029 )
2016
47
CardioPulse: Angina pectoris revisited. ( 27471763 )
2016
48
Comparison of the Effect of Rosuvastatin 2.5A mg vs 20A mg on Coronary Plaque Determined by Angioscopy and Intravascular Ultrasound in Japanese With Stable Angina Pectoris (from the Aggressive Lipid-Lowering Treatment Approach Using Intensive Rosuvastatin for Vulnerable Coronary Artery Plaque [ALTAIR] Randomized Trial). ( 26879069 )
2016
49
Reprising Ramadan-Related Angina Pectoris: A Potential Strategy for Risk Reduction. ( 27829657 )
2016
50
Impact of Paradoxical Decrease in High-Density Lipoprotein Cholesterol Levels After Statin Therapy on Major Adverse Cardiovascular Events in Patients with Stable Angina Pectoris. ( 28034517 )
2016

Variations for Angina Pectoris

Expression for Angina Pectoris

LifeMap Discovery
Genes differentially expressed in tissues of Angina Pectoris patients vs. healthy controls: 35
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1 EGR3 early growth response 3 Blood + 4.04 0.001
Search GEO for disease gene expression data for Angina Pectoris.

Pathways for Angina Pectoris

Pathways related to Angina Pectoris according to GeneCards Suite gene sharing:

(show all 11)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.84 F3 FGA KNG1 PLAT SERPINC1 SERPINE1
2
Show member pathways
12.52 F3 FGA KNG1 SERPINC1
3
Show member pathways
12 CRP IL6 PLAT SERPINE1
4
Show member pathways
11.76 F3 FGA KNG1 PLAT SERPINC1 SERPINE1
5 11.63 IL6 PLAT SERPINE1
6 11.58 F3 IL6 SERPINE1
7 11.37 F3 FGA KNG1 PLAT SERPINC1 SERPINE1
8 11.18 IL6 KNG1 PLAT
9 10.89 ACE PLAT
10 10.74 CRP IL6
11 10.55 PLAT SERPINE1 SERPINF2

GO Terms for Angina Pectoris

Cellular components related to Angina Pectoris according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.96 ACE CRP F3 FGA KNG1 PLAT
2 cell surface GO:0009986 9.78 F3 FGA PLAT SERPINF2
3 extracellular matrix GO:0031012 9.73 F3 PLAT SERPINE1 VWF
4 extracellular region GO:0005576 9.7 ACE CRP F3 FGA IL6 KNG1
5 endoplasmic reticulum lumen GO:0005788 9.67 FGA IL6 KNG1 SERPINC1
6 blood microparticle GO:0072562 9.62 FGA KNG1 SERPINC1 SERPINF2
7 platelet alpha granule lumen GO:0031093 9.55 FGA KNG1 SERPINE1 SERPINF2 VWF
8 platelet alpha granule GO:0031091 9.46 FGA VWF
9 fibrinogen complex GO:0005577 9.4 FGA SERPINF2
10 extracellular space GO:0005615 9.32 ACE CRP F3 FGA IL6 KNG1

Biological processes related to Angina Pectoris according to GeneCards Suite gene sharing:

(show all 21)
id Name GO ID Score Top Affiliating Genes
1 post-translational protein modification GO:0043687 9.84 FGA IL6 KNG1 SERPINC1
2 extracellular matrix organization GO:0030198 9.77 FGA SERPINE1 VWF
3 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.76 FGA IL6 SERPINF2
4 platelet activation GO:0030168 9.73 FGA IL6 VWF
5 cellular protein metabolic process GO:0044267 9.73 FGA IL6 KNG1 SERPINC1
6 negative regulation of endopeptidase activity GO:0010951 9.67 KNG1 SERPINC1 SERPINE1 SERPINF2
7 platelet degranulation GO:0002576 9.65 FGA KNG1 SERPINE1 SERPINF2 VWF
8 negative regulation of peptidase activity GO:0010466 9.62 KNG1 SERPINC1 SERPINE1 SERPINF2
9 negative regulation of endothelial cell apoptotic process GO:2000352 9.59 FGA SERPINE1
10 negative regulation of proteolysis GO:0045861 9.58 KNG1 PLAT
11 acute-phase response GO:0006953 9.58 CRP IL6 SERPINF2
12 blood coagulation, intrinsic pathway GO:0007597 9.57 KNG1 VWF
13 negative regulation of blood coagulation GO:0030195 9.55 KNG1 SERPINE1
14 plasminogen activation GO:0031639 9.52 FGA PLAT
15 neutrophil mediated immunity GO:0002446 9.51 ACE IL6
16 negative regulation of fibrinolysis GO:0051918 9.49 SERPINE1 SERPINF2
17 negative regulation of lipid storage GO:0010888 9.48 CRP IL6
18 negative regulation of plasminogen activation GO:0010757 9.46 SERPINE1 SERPINF2
19 fibrinolysis GO:0042730 9.46 FGA PLAT SERPINE1 SERPINF2
20 blood coagulation GO:0007596 9.43 F3 FGA KNG1 PLAT SERPINC1 VWF
21 hemostasis GO:0007599 9.02 F3 FGA KNG1 SERPINC1 VWF

Molecular functions related to Angina Pectoris according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 receptor binding GO:0005102 9.55 FGA IL6 KNG1 PLAT SERPINE1
2 serine-type endopeptidase inhibitor activity GO:0004867 9.43 SERPINC1 SERPINE1 SERPINF2
3 peptidase inhibitor activity GO:0030414 9.26 KNG1 SERPINC1 SERPINE1 SERPINF2
4 protease binding GO:0002020 9.02 F3 SERPINC1 SERPINE1 SERPINF2 VWF

Sources for Angina Pectoris

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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