MCID: ANG054
MIFTS: 53

Angina Pectoris

Categories: Cardiovascular diseases

Aliases & Classifications for Angina Pectoris

MalaCards integrated aliases for Angina Pectoris:

Name: Angina Pectoris 38 37 36

Classifications:



External Ids:

KEGG 36 H01632
ICD10 32 I20

Summaries for Angina Pectoris

MalaCards based summary : Angina Pectoris is related to coronary heart disease 1 and ischemic heart disease. An important gene associated with Angina Pectoris is CRP (C-Reactive Protein), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Covera-HS and Nitroglycerin have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and endothelial, and related phenotypes are cardiovascular system and hematopoietic system

Related Diseases for Angina Pectoris

Diseases related to Angina Pectoris via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 275)
# Related Disease Score Top Affiliating Genes
1 coronary heart disease 1 30.6 ACE CRP SERPINE1
2 ischemic heart disease 30.6 ACE CRP IL6
3 coronary restenosis 30.4 ACE SERPINC1
4 dressler's syndrome 30.2 CRP PLAT
5 systolic heart failure 30.2 ACE CRP IL6
6 sleep apnea 30.1 ACE CRP IL6
7 ischemia 30.1 ACE KNG1 PLAT
8 intermediate coronary syndrome 30.1 ACE CRP F3 IL6 PLAT SERPINC1
9 eisenmenger syndrome 29.9 PLAT VWF
10 antiphospholipid syndrome 29.8 F3 PLAT SERPINC1
11 coronary stenosis 29.7 ACE CRP IL6 SERPINE1 VWF
12 arteriosclerosis 29.5 ACE CRP F3 IL6 SERPINE1
13 essential thrombocythemia 29.4 F3 SERPINE1 VWF
14 thrombosis 29.2 F3 PLAT SERPINC1 SERPINE1 VWF
15 coronary artery anomaly 29.2 ACE CRP IL6 KNG1 PLAT SERPINE1
16 heart disease 28.8 ACE CRP F3 IL6 KNG1 SERPINC1
17 intermittent claudication 28.8 ACE CRP IL6 SERPINC1 SERPINE1 VWF
18 coronary thrombosis 28.5 F3 PLAT SERPINC1 SERPINE1 VWF
19 thrombophilia due to thrombin defect 28.5 F3 PLAT SERPINC1 SERPINE1 VWF
20 acute myocardial infarction 28.5 ACE CRP F3 PLAT SERPINC1 SERPINE1
21 peripheral vascular disease 27.9 ACE CRP F3 IL6 PLAT SERPINC1
22 pulmonary hypertension 27.8 ACE F3 IL6 PLAT SERPINC1 SERPINE1
23 arteries, anomalies of 27.8 ACE CRP F3 IL6 KNG1 PLAT
24 stroke, ischemic 27.4 ACE CRP F3 FGA PLAT SERPINC1
25 vascular disease 27.3 ACE CRP F3 KNG1 PLAT SERPINC1
26 myocardial infarction 27.1 ACE CRP F3 FGA IL6 KNG1
27 prinzmetal's variant angina 11.8
28 cold agglutinin disease 10.5 CRP IL6
29 diabetic foot ulcers 10.5 CRP IL6
30 cryopyrin-associated periodic syndrome 10.5 CRP IL6
31 neutrophilia, hereditary 10.5 CRP IL6
32 acute cholangitis 10.5 CRP IL6
33 uremic pruritus 10.5 CRP IL6
34 spinal disease 10.5 CRP IL6
35 castleman disease 10.5 CRP IL6
36 generalized atherosclerosis 10.5 ACE CRP
37 sudden sensorineural hearing loss 10.5 IL6 SERPINC1
38 endotheliitis 10.5
39 japanese spotted fever 10.5 CRP SERPINC1
40 viral pneumonia 10.5 CRP IL6
41 cecal disease 10.5 CRP IL6
42 relapsing polychondritis 10.5 CRP IL6
43 renal artery obstruction 10.5 ACE SERPINC1
44 central nervous system vasculitis 10.5 CRP IL6
45 subacute thyroiditis 10.5 CRP IL6
46 intussusception 10.5 CRP IL6
47 chronic thromboembolic pulmonary hypertension 10.5 CRP FGA
48 louse-borne relapsing fever 10.4 CRP IL6
49 hypersensitivity reaction type iii disease 10.4 CRP IL6
50 posterior urethral valves 10.4 ACE IL6

Graphical network of the top 20 diseases related to Angina Pectoris:



Diseases related to Angina Pectoris

Symptoms & Phenotypes for Angina Pectoris

MGI Mouse Phenotypes related to Angina Pectoris:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.91 IL6 PLAT SERPINC1 SERPINE1 ACE VWF
2 hematopoietic system MP:0005397 9.76 FGA IL6 PLAT SERPINC1 SERPINE1 ACE
3 homeostasis/metabolism MP:0005376 9.65 FGA IL6 PLAT SERPINC1 SERPINE1 ACE
4 immune system MP:0005387 9.28 FGA IL6 PLAT SERPINC1 SERPINE1 ACE

Drugs & Therapeutics for Angina Pectoris

FDA approved drugs:

# Drug Name Active Ingredient(s) 17 Company Approval Date
1
Covera-HS 17 VERAPAMIL HYDROCHLORIDE GD Searle, Alza January 1996

Drugs for Angina Pectoris (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 551)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Nitroglycerin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 55-63-0 4510
2
Atenolol Approved Phase 4,Phase 3,Phase 2,Phase 1 29122-68-7 2249
3
Nicorandil Approved, Investigational Phase 4,Phase 2 65141-46-0 47528
4
Methyltestosterone Approved Phase 4,Phase 3,Phase 2 58-18-4 6010
5
Testosterone Approved, Investigational Phase 4,Phase 3,Phase 2 58-22-0 6013
6
Pravastatin Approved Phase 4,Phase 3 81093-37-0 54687
7
Aspirin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 50-78-2 2244
8
Adenosine Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 58-61-7 60961
9
Ticagrelor Approved Phase 4,Phase 3,Phase 2,Phase 1 274693-27-5 9871419
10
Amiodarone Approved, Investigational Phase 4 1951-25-3 2157
11
Ranolazine Approved, Investigational Phase 4,Phase 3,Phase 2 95635-55-5, 142387-99-3 56959
12
Amlodipine Approved Phase 4,Phase 3,Phase 2 88150-42-9 2162
13
Angiotensin II Approved, Investigational Phase 4,Phase 3 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
14
Bisoprolol Approved Phase 4 66722-44-9 2405
15
Diltiazem Approved, Investigational Phase 4 42399-41-7 39186
16
Clopidogrel Approved Phase 4,Phase 3,Phase 2,Phase 1 120202-66-6, 113665-84-2 60606
17
Udenafil Approved, Investigational Phase 4 268203-93-6 6918523
18
Ramipril Approved Phase 4,Phase 3,Early Phase 1 87333-19-5 5362129
19
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2 33069-62-4 36314
20
Everolimus Approved Phase 4,Phase 3,Phase 2 159351-69-6 6442177
21
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2 53123-88-9 46835353 6436030 5284616
22
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
23
Pantoprazole Approved Phase 4,Phase 3 102625-70-7 4679
24
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1 55142-85-3 5472
25
Menthol Approved Phase 4,Phase 3 2216-51-5 16666
26
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 46507594 772
27
Chromium Approved Phase 4,Phase 2,Phase 3 7440-47-3 27668
28
Carvedilol Approved, Investigational Phase 4,Phase 1,Phase 2 72956-09-3 2585
29
Amiloride Approved Phase 4,Phase 2,Phase 3 2609-46-3, 2016-88-8 16231
30
Simvastatin Approved Phase 4,Phase 2,Phase 3,Phase 1 79902-63-9 54454
31
Telmisartan Approved, Investigational Phase 4 144701-48-4 65999
32
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
33
Citalopram Approved Phase 4,Phase 1,Phase 2 59729-33-8 2771
34
Colchicine Approved Phase 4,Phase 3 64-86-8 2833 6167
35
Etanercept Approved, Investigational Phase 4 185243-69-0
36
Bivalirudin Approved, Investigational Phase 4,Phase 3,Phase 2 128270-60-0 16129704
37
Tenecteplase Approved Phase 4 191588-94-0
38
Tirofiban Approved Phase 4,Phase 3,Phase 2 144494-65-5 60947
39
Hydroxocobalamin Approved Phase 4,Phase 3 13422-51-0 5460373 44475014 11953898
40
Losartan Approved Phase 4 114798-26-4 3961
41
Nitric Oxide Approved Phase 4,Phase 3,Phase 2,Phase 1 10102-43-9 145068
42
Metoprolol Approved, Investigational Phase 4,Early Phase 1 51384-51-1, 37350-58-6 4171
43
Isosorbide Dinitrate Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 87-33-2 6883
44
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 22916-47-8 4189
45
Pitavastatin Approved Phase 4 147511-69-1, 147526-32-7 5282452 6366718
46
Ethanol Approved Phase 4 64-17-5 702
47
Rivaroxaban Approved Phase 4,Phase 3,Phase 2 366789-02-8
48
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 2713 9552079
49 Molsidomine Approved, Investigational Phase 4 25717-80-0
50
Nebivolol Approved, Investigational Phase 4,Phase 1 152520-56-4, 118457-14-0, 99200-09-6 71301

Interventional clinical trials:

(show top 50) (show all 1300)

# Name Status NCT ID Phase Drugs
1 Spinal Cord Stimulation (SCS) in Refractory Angina Unknown status NCT00121654 Phase 4
2 Efficacy and Safety Study of Guanxin Shutong Capsule to Treat Chronic Stable Angina Unknown status NCT02280850 Phase 4 Guanxin Shutong Capsule;Placebo Capsule;nitroglycerine
3 Efficacy Study of Atorvastatin to Treat Variant Angina Unknown status NCT00620204 Phase 4 atorvastatin
4 Study to Assess Efficacy of Nicorandil+Atenolol vs Atenolol in Treatment of Chronic Stable Angina. Unknown status NCT01397994 Phase 4 Nicorandil;Atenolol
5 Testosterone Therapy on Angina Threshold and Atheroma in Patients With Chronic Stable Angina Unknown status NCT00131183 Phase 4 Nebido
6 The Effects of Pravastatin and Rosuvastatin on Coronary Plaques in Patients With Stable Angina Pectoris Unknown status NCT01325818 Phase 4 pravastatin, rosuvastatin
7 Clinical Study of Combination Therapy for Angina of Coronary Heart Disease With Aspirin and Salvianolate Injection Unknown status NCT02694848 Phase 4 Salvianolate injection;Aspirin
8 Effect of Ticagrelor on Adenosine-Induced Coronary Flow Reserve in Patients With Microvascular Angina Unknown status NCT02284048 Phase 4 ticagrelor
9 Safety of Amiodarone and Ranolazine Together in Patients With Angina Unknown status NCT01558830 Phase 4 ranolazine;placebo
10 A Pilot Study Exploring Efficacy and Safety of Amlodipine in the Stented Angina Patients Unknown status NCT01120327 Phase 4 Placebo;Amlodipine
11 Coronary Angioplasty in Octogenarians With Emergent Coronary Syndromes Unknown status NCT02126202 Phase 4
12 Comparison of Vascular Remodeling Between Different Antianginal Medication Evaluated by Noninvasive ECG-gated Fundus Photographic Evaluation Unknown status NCT01162902 Phase 4 Diltiazem treated group;Bisoprolol treated group;Candesartan treated group
13 Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Stable Angina, NSTEMI and STEMI Undergoing PCI Unknown status NCT02012140 Phase 4 ticagrelor
14 Understanding of Chest Pain in Microvascular Disease Proved by Cardiac Magnetic Resonance Image Unknown status NCT01769482 Phase 4 Udenafil;placebo
15 Statin and Angiotensin-converting Enzyme Inhibitor on Symptoms in Patients With SCAD Unknown status NCT02008786 Phase 4 ramipril;rosuvastatin;placebo
16 Small Coronary Artery Treated by TAXUS Liberté Registry in Japan Unknown status NCT00955214 Phase 4
17 Intensive Statin Therapy in PCI Patient With Acute Coronary Syndrome Unknown status NCT01372839 Phase 4 Atorvastatin;Statin
18 Ranolazine, Ethnicity and the Metabolic Syndrome Unknown status NCT01304095 Phase 4 Ranolazine
19 Optical Coherence Tomography Comparison of Neointimal Coverage Between CRE8 DES and BMS Unknown status NCT01543373 Phase 4
20 Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN) Unknown status NCT01735227 Phase 4 omeprazole;Pantoprazole
21 Efficacy Study of Nicorandil on Neointima Unknown status NCT02328521 Phase 4 Nicorandil;nicorandil placebo
22 Impact of Ticagrelor on the Endothelial Healing Following Drug-eluting Stent Implantation in the Patients With Acute Coronary Syndrome Unknown status NCT02037412 Phase 4 Ticagrelor;Clopidogrel
23 Clinical Evaluation of Magnetic Resonance Imaging in Coronary Heart Disease-2 Unknown status NCT01664858 Phase 4
24 A Trial to Evaluate Efficacy of Heart-protecting Musk Pill Unknown status NCT01897805 Phase 4 Heart-protecting Musk Pill;Placebo
25 Clinical Performance of CRE8 Drug Eluting Stent in All Comer Population Unknown status NCT01556126 Phase 4
26 DEDICA (Dose of HEparin During Coronary Angioplasty) Trial Unknown status NCT01694459 Phase 4 Low-dose heparin;Standard dose heparin
27 Ranolazine Loading to Prevent PCI-induced Myocardial Injury Unknown status NCT01491061 Phase 4 Ranolazine;Placebo
28 Comparative Phase IV Study: Efficacy And Safety of TiTAN2 Versus COBALT-CHROME Stents- EVIDENCEII Unknown status NCT01918150 Phase 4
29 Ischemia In Hemodialysed Patients: Ivabradine Versus Carvedilol Unknown status NCT01425164 Phase 4 Ivabradine;Carvedilol
30 Effects of Angiotensin II Receptor Blocker Compared With Diuretics in High-risk Hypertensive Patients Unknown status NCT01011660 Phase 4 Amlodipine, Telmisartan, Amiloride Compound , Simvastatin
31 Pravastatin for Acute Myocardial Infarction With Minimally to Mildly Increased Levels of Serum Cholesterol Study Unknown status NCT00688922 Phase 4 Pravastatin
32 Assessment of Coronary Flow Reserve by Doppler Flow WIre in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Differences Between the Loading Dose of Prasugrel and Ticagrelor . Unknown status NCT02032303 Phase 4 Ticagrelor loading;Prasugrel loading
33 Assessment of Coronary Flow Reserve by Doppler Flow Wire in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Differences Between the Loading Dose of Ticagrelor and Clopidogrel Unknown status NCT02032290 Phase 4 ticagrelor loading;Clopidogrel loading
34 Ranolazine for Improving Symptoms of Palpitations Unknown status NCT01495520 Phase 4 Ranolazine;Placebo
35 Italian Diffuse/Multivessel Disease ABSORB Prospective Registry: IT-Disappears Unknown status NCT02004730 Phase 4
36 A Prospective Multicenter Trial Evaluating Helios Biodegradable Polymer SES Safety and Effectiveness in CAD Treatment Unknown status NCT01880879 Phase 4
37 Effects of the Ivabradine on Reduction of Inflammatory Markers in Patients With Acute Coronary Syndrome Unknown status NCT00815100 Phase 4 Ivabradine;Placebo
38 The Effectiveness and Safety of Butylphthalide Soft Capsules in Secondary Prevention of Ischemic Stroke Trial Unknown status NCT00724724 Phase 4 Butylphthalide Soft Capsules;Aspirin
39 Testosterone for Peripheral Vascular Disease Unknown status NCT00504712 Phase 4 Testosterone;0.9% saline
40 The Canadian Prevention of Renal and Cardiovascular Endpoints Trial Unknown status NCT00231803 Phase 4
41 A Morbidity-Mortality and Remodeling Study With Valsartan Unknown status NCT00133328 Phase 4 valsartan
42 Effect of Ranolazine on Valvular Disease in Patients With Pacemakers Unknown status NCT01979965 Phase 4 Ranolazine (Active drug);Placebo
43 Effect of Testosterone on Endothelial Function and Microcirculation in Type 2 Diabetic Patients With Hypogonadism Unknown status NCT01084369 Phase 4 Testosterone
44 DECARD: Study of Escitalopram in the Prevention of Depression in Patients With Acute Coronary Syndrome Unknown status NCT00140257 Phase 4 Escitalopram
45 The Association Between Very Small Embryonic-like Stem Cells and the Prognosis of Coronary Artery Disease Patients Unknown status NCT01633359 Phase 4 Intensive statin;Routine statin
46 Bedside Testing of CYP2C19 Gene for Treatment of Patients With PCI With Antiplatelet Therapy Unknown status NCT01823185 Phase 4 clopidogrel;Ticagrelor or prasugrel
47 Colchicine for Acute Coronary Syndromes Unknown status NCT01906749 Phase 4 Colchicine;Placebo
48 Etanercept Treating Patient With Acute ST Segment Elevated Myocardial Infarction Unknown status NCT01372930 Phase 4 Etanercept;saline
49 Revascularization in Heart Failure Trial – REHEAT 2 Unknown status NCT00388245 Phase 4
50 Cocktail Injection Improves Outcomes of FFR Guided PCI Unknown status NCT02592720 Phase 4 cocktail

Search NIH Clinical Center for Angina Pectoris

Genetic Tests for Angina Pectoris

Anatomical Context for Angina Pectoris

MalaCards organs/tissues related to Angina Pectoris:

38
Heart, Testes, Endothelial, Kidney, Bone, Bone Marrow, Spinal Cord

Publications for Angina Pectoris

Articles related to Angina Pectoris:

(show top 50) (show all 846)
# Title Authors Year
1
Doppler Versus Thermodilution-Derived Coronary Microvascular Resistance to Predict Coronary Microvascular Dysfunction in Patients With Acute Myocardial Infarction or Stable Angina Pectoris. ( 29132649 )
2018
2
Economic Evaluation of Safflower Yellow Injection for the Treatment of Patients with Stable Angina Pectoris in China: A Cost-Effectiveness Analysis. ( 29431470 )
2018
3
Plasma 25-hydroxyvitamin D and mortality in patients with suspected stable angina pectoris. ( 29325121 )
2018
4
National Prevalence of Self-Reported Coronary Heart Disease and Chronic Stable Angina Pectoris: Factor Analysis of the Underlying Cardiometabolic Risk Factors in the Fourth Round of the SuRFNCD-2011. ( 29434010 )
2018
5
Accelerated collagen turnover in women with angina pectoris without obstructive coronary artery disease: An iPOWER substudy. ( 29436257 )
2018
6
Blood rheology of angina pectoris patients with myocardial injury after ischemia reperfusion and its effect on thromboxane B<sub>2</sub>levels. ( 29399084 )
2018
7
Sodium Tanshinone II A Sulfonate Injection as Adjuvant Treatment for Unstable Angina Pectoris: A Meta-Analysis of 17 Randomized Controlled Trials. ( 29181731 )
2018
8
Serum Carnitine Metabolites and Incident Type 2 Diabetes Mellitus in Patients with Suspected Stable Angina Pectoris. ( 29325058 )
2018
9
Effect of Kuanxiong Aerosol () on Patients with Angina Pectoris: A Non-inferiority Multi-center Randomized Controlled Trial. ( 29435729 )
2018
10
High-Sensitivity Cardiac Troponin I and the Diagnosis of Coronary Artery Disease in Patients With Suspected Angina Pectoris. ( 29444926 )
2018
11
The associatA+on between serum serglycin level and coronary artery disease severity in patients with stable angina pectoris. ( 29313562 )
2018
12
Prasugrel as opposed to clopidogrel improves endothelial nitric oxide bioavailability and reduces platelet-leukocyte interaction in patients with unstable angina pectoris: A randomized controlled trial. ( 28709700 )
2017
13
Research of Medical Expenditure among Inpatients with Unstable Angina Pectoris in a Single Center. ( 28639566 )
2017
14
Moderate-dose atorvastatin improves arterial endothelial function in patients with angina pectoris and normal coronary angiogram: a pilot study. ( 28721151 )
2017
15
Chronic refractory angina pectoris: recent progress and remaining challenges. ( 28903477 )
2017
16
Effects of trimetazidine on periprocedural microRNA-21 expression by CD4+ T lymphocytes in patients with unstable angina pectoris. ( 29285227 )
2017
17
A novel biochemical marker for predicting the severity of acute coronary syndrome with unstable angina pectoris: Asprosin. ( 29274804 )
2017
18
Relationship of mean platelet volume to lymphocyte ratio and coronary collateral circulation in patients with stable angina pectoris. ( 28678144 )
2017
19
Cluster analysis for syndromes of real-world coronary heart disease with angina pectoris. ( 29209917 )
2017
20
Efficacy of spinal cord stimulation as an adjunct therapy for chronic refractory angina pectoris. ( 27836302 )
2017
21
SYNTAX Score and Pre- and Poststent Optical Coherence Tomography Findings in the Left Anterior Descending Coronary Artery in Patients With Stable Angina Pectoris. ( 28750824 )
2017
22
In vitro inhibition of platelets aggregation with generic form of clopidogrel versus branded in patients with stable angina pectoris. ( 29391931 )
2017
23
Effectiveness and safety of anti-ischemic trimetazidine in patients with stable angina pectoris and Type 2 diabetes. ( 29148291 )
2017
24
Panax notoginseng Preparations for Unstable Angina Pectoris: A Systematic Review and Meta-Analysis. ( 28634988 )
2017
25
The value of peripheral blood eosinophil count in predicting in-stent restenosis in patients with stable angina pectoris undergoing drug eluting stenting. ( 28672766 )
2017
26
Coronary microvascular dysfunction is not associated with a history of reproductive risk factors in women with angina pectoris-An iPOWER substudy. ( 28807722 )
2017
27
Evaluation of local carotid stiffness and inflammatory biomarkers in stable angina pectoris. ( 28798782 )
2017
28
Statins in Stable Angina Pectoris. ( 28847306 )
2017
29
Serum Uric Acid Could Differentiate Acute Myocardial Infarction and Unstable Angina Pectoris in Hyperuricemic Acute Coronary Syndrome Patients. ( 28790542 )
2017
30
The effect of Danshen extract on lipoprotein-associated phospholipase A<sub>2</sub>levels in patients with stable angina pectoris: study protocol for a randomized controlled trial - the DOLPHIN study. ( 29262859 )
2017
31
High Resting Heart Rate and High BMI Predicted Severe Coronary Atherosclerosis Burden in Patients With Stable Angina Pectoris by SYNTAX Score. ( 28635302 )
2017
32
Microfluidic assay of circulating endothelial cells in coronary artery disease patients with angina pectoris. ( 28704506 )
2017
33
Practice of Comparative Effectiveness Research to Identify Treatment Characteristics of Similar Chinese Patent Medicine for Angina Pectoris. ( 28894471 )
2017
34
Serial 3-Vessel Optical Coherence Tomography and Intravascular Ultrasound Analysis of Changing Morphologies Associated With Lesion Progression in Patients With Stable Angina Pectoris. ( 28893795 )
2017
35
Ventricular repolarization alterations in women with angina pectoris and suspected coronary microvascular dysfunction. ( 28939174 )
2017
36
Metabolomic Evaluation of the Consequences of Plasma Cystathionine Elevation in Adults with Stable Angina Pectoris. ( 28794210 )
2017
37
A Successfully Treated Case of Gastrointestinal Stromal Tumor Causing Severe Anemia and Localized Peritonitis Showing Angina Pectoris Resulting in Watershed Cerebral Infarction. ( 28912818 )
2017
38
Comparison of the Brachial-Ankle Pulse Wave Velocity between Patients with Acute Coronary Syndrome and Effort Angina Pectoris. ( 29269651 )
2017
39
How Efficacious is Danshen (Salvia miltiorrhiza) Dripping Pill in Treating Angina Pectoris? Evidence Assessment for Meta-Analysis of Randomized Controlled Trials. ( 28650203 )
2017
40
The Efficacy of Danshen Injection as Adjunctive Therapy in Treating Angina Pectoris: A Systematic Review and Meta-Analysis. ( 29150156 )
2017
41
The association between electrocardiographic R wave peak time and coronary artery disease severity in patients with non-ST segment elevation myocardial infarction and unstable angina pectoris. ( 29108790 )
2017
42
Unstable Angina Pectoris in a 22-year-old Female Patient. ( 28090005 )
2017
43
Propranolol for Angina Pectoris. ( 27828838 )
2016
44
Endothelial immunomediated reactivity in acute cardiac ischaemia: Role of endothelin 1, interleukin 8 and NT-proBNP in patients affected by unstable angina pectoris. ( 26684625 )
2016
45
Anti-Anginal and Metabolic Effects of Carvedilol and Atenolol in Patients with Stable Angina Pectoris: A Prospective, Randomized, Parallel, Open-Label Study. ( 27021556 )
2016
46
CardioPulse: Angina pectoris revisited. ( 27471763 )
2016
47
Alternative complement pathway activation during invasive coronary procedures in acute myocardial infarction and stable angina pectoris. ( 27794429 )
2016
48
Methylenetetrahydrofolate Dehydrogenase 1 Polymorphisms Modify the Associations of Plasma Glycine and Serine With Risk of Acute Myocardial Infarction in Patients With Stable Angina Pectoris in WENBIT (Western Norway B Vitamin Intervention Trial). ( 27872106 )
2016
49
Dental Calculus Links Statistically to Angina Pectoris: 26-Year Observational Study. ( 27336307 )
2016
50
Spinal Cord Stimulation for Refractory Angina Pectoris: A Systematic Review and Meta-analysis. ( 27875377 )
2016

Variations for Angina Pectoris

Expression for Angina Pectoris

LifeMap Discovery
Genes differentially expressed in tissues of Angina Pectoris patients vs. healthy controls: 35
# Gene Description Tissue Up/Dn Fold Change (log2) P value
1 EGR3 early growth response 3 Blood + 4.04 0.001
Search GEO for disease gene expression data for Angina Pectoris.

Pathways for Angina Pectoris

Pathways related to Angina Pectoris according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.84 F3 FGA KNG1 PLAT SERPINC1 SERPINE1
2
Show member pathways
12.52 F3 FGA KNG1 SERPINC1
3
Show member pathways
12 CRP IL6 PLAT SERPINE1
4
Show member pathways
11.76 F3 FGA KNG1 PLAT SERPINC1 SERPINE1
5 11.63 IL6 PLAT SERPINE1
6 11.58 F3 IL6 SERPINE1
7 11.37 F3 FGA KNG1 PLAT SERPINC1 SERPINE1
8 11.18 IL6 KNG1 PLAT
9 10.84 ACE PLAT
10 10.74 CRP IL6
11 10.55 PLAT SERPINE1 SERPINF2

GO Terms for Angina Pectoris

Cellular components related to Angina Pectoris according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.96 ACE CRP F3 FGA KNG1 PLAT
2 cell surface GO:0009986 9.78 F3 FGA PLAT SERPINF2
3 extracellular matrix GO:0031012 9.72 F3 KNG1 PLAT SERPINE1 VWF
4 endoplasmic reticulum lumen GO:0005788 9.71 FGA IL6 KNG1 SERPINC1
5 blood microparticle GO:0072562 9.67 FGA KNG1 SERPINC1 SERPINF2
6 extracellular space GO:0005615 9.65 ACE CRP F3 FGA IL6 KNG1
7 platelet alpha granule lumen GO:0031093 9.55 FGA KNG1 SERPINE1 SERPINF2 VWF
8 platelet alpha granule GO:0031091 9.46 FGA VWF
9 fibrinogen complex GO:0005577 9.43 FGA SERPINF2
10 extracellular region GO:0005576 9.36 ACE CRP F3 FGA IL6 KNG1

Biological processes related to Angina Pectoris according to GeneCards Suite gene sharing:

(show all 20)
# Name GO ID Score Top Affiliating Genes
1 post-translational protein modification GO:0043687 9.84 FGA IL6 KNG1 SERPINC1
2 extracellular matrix organization GO:0030198 9.77 FGA SERPINE1 VWF
3 cellular protein metabolic process GO:0044267 9.73 FGA IL6 KNG1 SERPINC1
4 platelet activation GO:0030168 9.72 FGA IL6 VWF
5 negative regulation of endopeptidase activity GO:0010951 9.67 KNG1 SERPINC1 SERPINE1 SERPINF2
6 platelet degranulation GO:0002576 9.65 FGA KNG1 SERPINE1 SERPINF2 VWF
7 negative regulation of peptidase activity GO:0010466 9.62 KNG1 SERPINC1 SERPINE1 SERPINF2
8 negative regulation of endothelial cell apoptotic process GO:2000352 9.58 FGA SERPINE1
9 negative regulation of proteolysis GO:0045861 9.58 KNG1 PLAT
10 acute-phase response GO:0006953 9.58 CRP IL6 SERPINF2
11 blood coagulation, intrinsic pathway GO:0007597 9.57 KNG1 VWF
12 negative regulation of blood coagulation GO:0030195 9.56 KNG1 SERPINE1
13 plasminogen activation GO:0031639 9.52 FGA PLAT
14 neutrophil mediated immunity GO:0002446 9.51 ACE IL6
15 negative regulation of fibrinolysis GO:0051918 9.49 SERPINE1 SERPINF2
16 negative regulation of lipid storage GO:0010888 9.48 CRP IL6
17 negative regulation of plasminogen activation GO:0010757 9.46 SERPINE1 SERPINF2
18 fibrinolysis GO:0042730 9.46 FGA PLAT SERPINE1 SERPINF2
19 blood coagulation GO:0007596 9.43 F3 FGA KNG1 PLAT SERPINC1 VWF
20 hemostasis GO:0007599 9.02 F3 FGA KNG1 SERPINC1 VWF

Molecular functions related to Angina Pectoris according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 receptor binding GO:0005102 9.56 FGA KNG1 PLAT SERPINE1
2 serine-type endopeptidase inhibitor activity GO:0004867 9.33 SERPINC1 SERPINE1 SERPINF2
3 peptidase inhibitor activity GO:0030414 9.26 KNG1 SERPINC1 SERPINE1 SERPINF2
4 protease binding GO:0002020 9.02 F3 SERPINC1 SERPINE1 SERPINF2 VWF

Sources for Angina Pectoris

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
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36 KEGG
37 LifeMap
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58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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