MCID: ANG050
MIFTS: 26

Angiocentric Glioma malady

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Angiocentric Glioma

Aliases & Descriptions for Angiocentric Glioma:

Name: Angiocentric Glioma 56 69

Characteristics:

Orphanet epidemiological data:

56
angiocentric glioma
Prevalence: <1/1000000 (Worldwide); Age of onset: All ages; Age of death: normal life expectancy;

Classifications:

Orphanet: 56  
Rare neurological diseases


External Ids:

Orphanet 56 ORPHA251671
UMLS via Orphanet 70 C2363903
ICD10 via Orphanet 34 C71.9

Summaries for Angiocentric Glioma

MalaCards based summary : Angiocentric Glioma is related to glioma and angiofollicular lymph hyperplasia. An important gene associated with Angiocentric Glioma is QKI (QKI, KH Domain Containing RNA Binding), and among its related pathways/superpathways are Neural Stem Cell Differentiation Pathways and Lineage-specific Markers and Cell adhesion_Cadherin-mediated cell adhesion. Affiliated tissues include brain and temporal lobe, and related phenotypes are Increased shRNA abundance (Z-score > 2) and cardiovascular system

Related Diseases for Angiocentric Glioma

Diseases related to Angiocentric Glioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 166)
id Related Disease Score Top Affiliating Genes
1 glioma 10.6
2 angiofollicular lymph hyperplasia 10.2 ACTC1 GFAP
3 vagina leiomyosarcoma 10.2 ACTC1 GFAP
4 middle ear disease 10.2 GFAP IDH1
5 epilepsy 10.2
6 childhood embryonal testis carcinoma 10.2 GFAP IDH1
7 acute generalized exanthematous pustulosis 10.2 ACTC1 S100B
8 chiasmal syndrome 10.2 ACTC1 S100B
9 hemangioma of liver 10.2 ACTC1 S100B
10 amyloid tumor 10.2 GFAP IDH1
11 myelinoclastic diffuse sclerosis 10.2 GFAP S100B
12 bronchial mucus gland adenoma 10.2 GFAP S100B
13 ovarian cystadenoma 10.2 GFAP S100B
14 trombiculiasis 10.2 GFAP S100B
15 porokeratosis 10.2 GFAP S100B
16 cutaneous adenocystic carcinoma 10.2 GFAP IDH1
17 diabetes hypogonadism deafness mental retardation 10.1 GFAP SYP
18 brain stem ependymoma 10.1 GFAP SYP
19 intrahepatic bile duct adenoma 10.1 GFAP SYP
20 pilocytic astrocytoma of cerebellum 10.1 GFAP SYP
21 children's interstitial lung disease 10.1 GFAP SYP
22 plasmodium ovale malaria 10.1 ACTC1 GFAP
23 cervical benign neoplasm 10.1 GFAP SYP
24 epidermal appendage tumor 10.1 GFAP SYP
25 clear cell meningioma 10.1 GFAP SYP
26 cerebral folate receptor alpha deficiency 10.1 GFAP SYP
27 vulvar benign neoplasm 10.1 GFAP SYP
28 paraphimosis 10.1 ACTC1 SYP
29 pilocytic astrocytoma 10.1 GFAP SYP
30 blood group incompatibility 10.1 GFAP SYP
31 pleomorphic xanthoastrocytoma 10.1 GFAP SYP
32 mediastinal granular cell myoblastoma 10.1 GFAP SYP
33 central neurocytoma 10.1 GFAP SYP
34 mast-cell sarcoma 10.1 GFAP SYP
35 olfactory neuroblastoma 10.1 GFAP SYP
36 superior vena cava syndrome 10.1 GFAP SYP
37 pineoblastoma 10.1 GFAP SYP
38 hunter macpherson syndrome 10.1 ACTC1 SYP
39 corneal intraepithelial neoplasm 10.1 S100B SYP
40 hypoparathyroidism-intellectual disability-dysmorphism syndrome 10.1 S100B SYP
41 pneumothorax 10.1 GFAP SYP
42 monkeypox 10.1 S100B SYP
43 brain stem astrocytic neoplasm 10.1 GFAP SYP
44 movement disease 10.1 S100B SYP
45 dysgerminoma of ovary 10.1 GFAP SYP
46 lymphomatoid papulosis 10.1 ACTC1 VIM
47 chest wall parachordoma 10.1 ACTC1 VIM
48 early-onset parkinson disease 10.1 S100B SYP
49 bone deterioration disease 10.1 S100B SYP
50 isolated anterior cervical hypertrichosis 10.1 ACTC1 VIM

Graphical network of the top 20 diseases related to Angiocentric Glioma:



Diseases related to Angiocentric Glioma

Symptoms & Phenotypes for Angiocentric Glioma

GenomeRNAi Phenotypes related to Angiocentric Glioma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.66 MYB
2 Increased shRNA abundance (Z-score > 2) GR00366-A-107 9.66 ACTC1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-120 9.66 MYB
4 Increased shRNA abundance (Z-score > 2) GR00366-A-121 9.66 MYB
5 Increased shRNA abundance (Z-score > 2) GR00366-A-122 9.66 MYB ACTC1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-127 9.66 IDH1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-136 9.66 IDH1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-138 9.66 IDH1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-147 9.66 MYB ACTC1 IDH1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.66 MYB
11 Increased shRNA abundance (Z-score > 2) GR00366-A-164 9.66 MYB
12 Increased shRNA abundance (Z-score > 2) GR00366-A-169 9.66 MYB
13 Increased shRNA abundance (Z-score > 2) GR00366-A-172 9.66 IDH1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.66 MYB
15 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.66 ACTC1
16 Increased shRNA abundance (Z-score > 2) GR00366-A-39 9.66 IDH1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-47 9.66 IDH1
18 Increased shRNA abundance (Z-score > 2) GR00366-A-73 9.66 MYB
19 Increased shRNA abundance (Z-score > 2) GR00366-A-83 9.66 MYB

MGI Mouse Phenotypes related to Angiocentric Glioma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.43 ACTC1 GFAP MYB PTPRJ QKI VIM
2 normal MP:0002873 9.1 ACTC1 GFAP MYB PTPRJ S100B SYP

Drugs & Therapeutics for Angiocentric Glioma

Search Clinical Trials , NIH Clinical Center for Angiocentric Glioma

Genetic Tests for Angiocentric Glioma

Anatomical Context for Angiocentric Glioma

MalaCards organs/tissues related to Angiocentric Glioma:

39
Brain, Temporal Lobe

Publications for Angiocentric Glioma

Articles related to Angiocentric Glioma:

(show all 41)
id Title Authors Year
1
Angiocentric Glioma in an Elderly Patient: Case Report and Review of the Literature. ( 27756673 )
2017
2
MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism. ( 26829751 )
2016
3
MYB-QKI Fusions Drive Angiocentric Glioma through Multiple Mechanisms. ( 26869254 )
2016
4
Angiocentric glioma transformed into anaplastic ependymoma: Review of the evidence for malignant potential. ( 27742374 )
2016
5
Angiocentric glioma from a perspective of A-B-C classification of epilepsy associated tumors. ( 27179220 )
2016
6
Angiocentric glioma of hippocampus-report of a rare intractable epilepsy-related tumor. ( 26954821 )
2016
7
Cystoid angiocentric glioma: A case report and literature review. ( 26629293 )
2015
8
"Unusual brain stone": heavily calcified primary neoplasm with some features suggestive of angiocentric glioma. ( 26024003 )
2015
9
MR Spectroscopic Profile of an Angiocentric Glioma. ( 26504061 )
2015
10
Angiocentric Glioma: The Infiltrative Glioma with Ependymal Differentiation. ( 24913299 )
2014
11
Angiocentric glioma: A report of nine new cases, including four with atypical histological features. ( 24861831 )
2014
12
Well-differentiated pediatric glial neoplasms with features of oligodendroglioma, angiocentric glioma and dysembryoplastic neuroepithelial tumors: a morphological diagnostic challenge. ( 24448703 )
2014
13
Angiocentric glioma: a rare intractable epilepsy-related tumour in children. ( 25310736 )
2014
14
Intractable epilepsy due to angiocentric glioma: A case report and minireview. ( 24348765 )
2014
15
Angiocentric glioma: a treatable cause of epilepsy: report of a rare case. ( 25591686 )
2014
16
Angiocentric glioma, a recently added WHO grade-I tumor. ( 27330646 )
2013
17
The treatment of angiocentric glioma: case report and literature review. ( 23596378 )
2013
18
Angiocentric glioma. ( 24116979 )
2013
19
Angiocentric glioma: clinical, morphological, immunohistochemical and molecular features in three pediatric cases. ( 23073165 )
2013
20
Angiocentric glioma in a 4-year-old boy: imaging characteristics and review of the literature. ( 22226445 )
2012
21
Adult-onset angiocentric glioma of epithelioid cell-predominant type of the mesial temporal lobe suggestive of a rare but distinct clinicopathological subset within a spectrum of angiocentric cortical ependymal tumors. ( 22151480 )
2012
22
Isocitrate dehydrogenase 1 R132H mutation is not detected in angiocentric glioma. ( 22445362 )
2012
23
The high mitotic count detected by phospho-histone H3 immunostain does not alter the benign behavior of angiocentric glioma. ( 21892765 )
2012
24
Refractory temporal lobe epilepsy caused by angiocentric glioma complicated with focal cortical dysplasia: a surgical case series. ( 23065092 )
2012
25
Imaging characteristics of an unusual, high-grade angiocentric glioma: a case report and review of the literature. ( 23378871 )
2012
26
Angiocentric glioma: a clinicopathologic review of 5 tumors with identification of associated cortical dysplasia. ( 21809996 )
2011
27
Angiocentric glioma and surrounding cortical dysplasia manifesting as intractable frontal lobe epilepsy--case report. ( 21785249 )
2011
28
A case of angiocentric glioma with unusual clinical and radiological features. ( 21887397 )
2011
29
Angiocentric glioma with high proliferative index: case report and review of the literature. ( 22075509 )
2011
30
Angiocentric glioma with rich blood supply. ( 20399664 )
2010
31
Paroxysmal ictal phonemes in a patient with angiocentric glioma. ( 20160231 )
2010
32
Angiocentric glioma: a case report and review of the literature. ( 19941376 )
2010
33
Angiocentric glioma: a case series. ( 19338465 )
2009
34
Angiocentric glioma-like tumor of the midbrain. ( 20110754 )
2009
35
Angiocentric glioma-induced seizures in a 2-year-old child. ( 19304961 )
2009
36
Cortical ependymoma or monomorphous angiocentric glioma? ( 18021197 )
2008
37
Angiocentric glioma: presentation of two cases with dissimilar histology. ( 19130736 )
2008
38
Brain surface spindle cell glioma in a patient with medically intractable partial epilepsy: a variant of monomorphous angiocentric glioma? ( 18179412 )
2008
39
Angiocentric glioma: report of clinico-pathologic and genetic findings in 8 cases. ( 18059228 )
2007
40
Newly codified glial neoplasms of the 2007 WHO Classification of Tumours of the Central Nervous System: angiocentric glioma, pilomyxoid astrocytoma and pituicytoma. ( 17598825 )
2007
41
Monomorphous angiocentric glioma: a distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymoma. ( 16215459 )
2005

Variations for Angiocentric Glioma

Expression for Angiocentric Glioma

Search GEO for disease gene expression data for Angiocentric Glioma.

Pathways for Angiocentric Glioma

Pathways related to Angiocentric Glioma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.83 GFAP S100B SYP VIM
2 10.56 ACTC1 PTPRJ

GO Terms for Angiocentric Glioma

Biological processes related to Angiocentric Glioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 muscle filament sliding GO:0030049 8.96 ACTC1 VIM
2 regulation of neuronal synaptic plasticity GO:0048168 8.62 S100B SYP

Molecular functions related to Angiocentric Glioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.92 GFAP S100B SYP VIM

Sources for Angiocentric Glioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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