MCID: ANG050
MIFTS: 40

Angiocentric Glioma malady

Neuronal diseases, Cancer diseases, Rare diseases categories

Summaries for Angiocentric Glioma

About this section


MalaCards based summary: Angiocentric Glioma is related to ependymoma and astrocytoma. An important gene associated with Angiocentric Glioma is ACTC1 (actin, alpha, cardiac muscle 1), and among its related pathways are Striated Muscle Contraction and Nuclear signaling by ERBB4. The compounds 2-methoxyethanol and n-acetylaspartate have been mentioned in the context of this disorder. Affiliated tissues include temporal lobe and brain, and related mouse phenotypes are muscle and homeostasis/metabolism.

Aliases & Classifications for Angiocentric Glioma

About this section
Sources:
49Orphanet, 62UMLS, 63UMLS via Orphanet
See all sources

Angiocentric Glioma, Aliases & Descriptions:

Name: Angiocentric Glioma 49 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Neuronal diseases


Characteristics (Orphanet epidemiological data):

49
angiocentric glioma:
Prevalence: <1/1000000 (Worldwide); Age of onset: All ages; Age of death: normal life expectancy


External Ids:

Orphanet49 251671
UMLS via Orphanet63 C2363903

Related Diseases for Angiocentric Glioma

About this section

Diseases related to Angiocentric Glioma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 93)
idRelated DiseaseScoreTop Affiliating Genes
1ependymoma30.5S100B, SYP, VIM, GFAP
2astrocytoma30.4IDH1, GFAP, SYP, VIM, S100B
3dysembryoplastic neuroepithelial tumor30.4SYP
4oligodendroglioma30.3IDH1, GFAP, SYP
5temporal lobe epilepsy10.2
6frontal lobe epilepsy10.2
7pilomyxoid astrocytoma10.2
8pituicytoma10.2
9melanotic neuroectodermal tumor10.1SYP
10giant cell glioblastoma10.0GFAP
11choroid plexus papilloma10.0GFAP
12histiocytosis10.0S100B
13mixed glioma10.0GFAP
14papilloma10.0ACTC1
15neurilemmoma10.0GFAP
16gliomatosis cerebri10.0GFAP
17gliosarcoma10.0GFAP
18epithelioid leiomyosarcoma10.0ACTC1, VIM
19pseudosarcomatous fibromatosis10.0ACTC1, VIM
20spindle cell carcinoma10.0VIM, ACTC1
21cutaneous fibrous histiocytoma10.0ACTC1, S100B
22tubular adenocarcinoma10.0ACTC1, SYP
23endometrial stromal sarcoma10.0VIM, ACTC1
24angiomyolipoma10.0ACTC1, VIM
25fibroma10.0VIM, ACTC1
26subependymal giant cell astrocytoma10.0S100B, SYP
27fibromatosis10.0VIM, ACTC1
28olfactory neuroblastoma10.0SYP, S100B
29angiosarcoma10.0VIM, ACTC1
30sertoli cell tumor10.0SYP, VIM
31ganglioneuroblastoma10.0S100B, SYP
32abrikosov's tumor10.0ACTC1, VIM
33binswanger's disease10.0GFAP, SYP
34syringoma10.0GFAP, S100B
35central neurocytoma10.0SYP, GFAP
36perineurioma10.0S100B, VIM
37sex cord-gonadal stromal tumor10.0S100B, VIM
38microphthalmia10.0ACTC1, S100B
39amyotrophic lateral sclerosis 110.0SYP, GFAP
40myxopapillary ependymoma10.0GFAP, S100B
41neuroendocrine tumor10.0S100B, SYP
42rhabdoid meningioma10.0GFAP, VIM
43pineoblastoma10.0GFAP, SYP
44astroblastoma10.0VIM, GFAP
45oxyphilic adenoma10.0SYP, VIM
46choroid plexus carcinoma10.0S100B, GFAP
47anaplastic ependymoma10.0S100B, GFAP
48gemistocytic astrocytoma10.0GFAP, S100B
49teratoma10.0GFAP, ACTC1
50malignant peripheral nerve sheath tumor10.0VIM, S100B

Graphical network of the top 20 diseases related to Angiocentric Glioma:



Diseases related to angiocentric glioma

Symptoms for Angiocentric Glioma

About this section

Drugs & Therapeutics for Angiocentric Glioma

About this section

Drug clinical trials:

Search ClinicalTrials for Angiocentric Glioma

Search NIH Clinical Center for Angiocentric Glioma

Genetic Tests for Angiocentric Glioma

About this section

Anatomical Context for Angiocentric Glioma

About this section

MalaCards organs/tissues related to Angiocentric Glioma:

33
Temporal lobe, Brain

Animal Models for Angiocentric Glioma or affiliated genes

About this section

MGI Mouse Phenotypes related to Angiocentric Glioma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053697.8GFAP, PTPRJ, VIM, ACTC1
2MP:00053767.7ACTC1, VIM, PTPRJ, GFAP, IDH1
3MP:00028737.6S100B, SYP, ACTC1, PTPRJ, GFAP

Publications for Angiocentric Glioma

About this section

Articles related to Angiocentric Glioma:

(show all 31)
idTitleAuthorsYear
1
Angiocentric glioma: a treatable cause of epilepsy: report of a rare case. (25591686)
2014
2
Angiocentric glioma: A report of nine new cases, including four with atypical histological features. (24861831)
2014
3
Angiocentric glioma: a rare intractable epilepsy-related tumour in children. (25310736)
2014
4
Angiocentric Glioma: The Infiltrative Glioma with Ependymal Differentiation. (24913299)
2014
5
Intractable epilepsy due to angiocentric glioma: A case report and minireview. (24348765)
2014
6
Well-differentiated pediatric glial neoplasms with features of oligodendroglioma, angiocentric glioma and dysembryoplastic neuroepithelial tumors: a morphological diagnostic challenge. (24448703)
2014
7
Angiocentric glioma: clinical, morphological, immunohistochemical and molecular features in three pediatric cases. (23073165)
2013
8
Angiocentric glioma. (24116979)
2013
9
The treatment of angiocentric glioma: case report and literature review. (23596378)
2013
10
Angiocentric glioma in a 4-year-old boy: imaging characteristics and review of the literature. (22226445)
2012
11
Adult-onset angiocentric glioma of epithelioid cell-predominant type of the mesial temporal lobe suggestive of a rare but distinct clinicopathological subset within a spectrum of angiocentric cortical ependymal tumors. (22151480)
2012
12
Imaging characteristics of an unusual, high-grade angiocentric glioma: a case report and review of the literature. (23378871)
2012
13
Isocitrate dehydrogenase 1 R132H mutation is not detected in angiocentric glioma. (22445362)
2012
14
Refractory temporal lobe epilepsy caused by angiocentric glioma complicated with focal cortical dysplasia: a surgical case series. (23065092)
2012
15
The high mitotic count detected by phospho-histone H3 immunostain does not alter the benign behavior of angiocentric glioma. (21892765)
2012
16
Angiocentric glioma and surrounding cortical dysplasia manifesting as intractable frontal lobe epilepsy--case report. (21785249)
2011
17
Angiocentric glioma: a clinicopathologic review of 5 tumors with identification of associated cortical dysplasia. (21809996)
2011
18
A case of angiocentric glioma with unusual clinical and radiological features. (21887397)
2011
19
Angiocentric glioma with high proliferative index: case report and review of the literature. (22075509)
2011
20
Paroxysmal ictal phonemes in a patient with angiocentric glioma. (20160231)
2010
21
Angiocentric glioma with rich blood supply. (20399664)
2010
22
Angiocentric glioma: a case report and review of the literature. (19941376)
2010
23
Angiocentric glioma: a case series. (19338465)
2009
24
Angiocentric glioma-like tumor of the midbrain. (20110754)
2009
25
Angiocentric glioma-induced seizures in a 2-year-old child. (19304961)
2009
26
Brain surface spindle cell glioma in a patient with medically intractable partial epilepsy: a variant of monomorphous angiocentric glioma? (18179412)
2008
27
Cortical ependymoma or monomorphous angiocentric glioma? (18021197)
2008
28
Angiocentric glioma: presentation of two cases with dissimilar histology. (19130736)
2008
29
Newly codified glial neoplasms of the 2007 WHO Classification of Tumours of the Central Nervous System: angiocentric glioma, pilomyxoid astrocytoma and pituicytoma. (17598825)
2007
30
Angiocentric glioma: report of clinico-pathologic and genetic findings in 8 cases. (18059228)
2007
31
Monomorphous angiocentric glioma: a distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymoma. (16215459)
2005

Variations for Angiocentric Glioma

About this section

Expression for genes affiliated with Angiocentric Glioma

About this section

Search GEO for disease gene expression data for Angiocentric Glioma.

Pathways for genes affiliated with Angiocentric Glioma

About this section

Pathways related to Angiocentric Glioma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.6ACTC1, VIM
2
Show member pathways
9.3S100B, GFAP
39.3ACTC1, PTPRJ
48.9S100B, SYP, GFAP

Compounds for genes affiliated with Angiocentric Glioma

About this section

Compounds related to Angiocentric Glioma according to GeneCards/GeneDecks:

(show top 50)    (show all 71)
idCompoundScoreTop Affiliating Genes
12-methoxyethanol459.9ACTC1, VIM
2n-acetylaspartate459.7SYP, GFAP
34-aminopyridine45 3010.7SYP, VIM
42,3-cyclic nucleotide459.6S100B, GFAP
5retinaldehyde459.6GFAP, VIM
6l-amino acid459.5SYP, S100B
7orcein459.5ACTC1, S100B, VIM
8silicone459.4GFAP, VIM
9catecholamine459.3S100B, VIM, SYP
10streptozotocin459.3GFAP, VIM, SYP
11eosin459.2S100B, VIM, GFAP
12ganglioside459.2GFAP, SYP, VIM
135-hydroxytryptamine459.2SYP, VIM, GFAP
14matrigel459.2VIM, GFAP, ACTC1
15cocaine45 1310.1GFAP, VIM, S100B
16etoposide45 51 61 1312.1SYP, S100B, VIM
17bromodeoxyuridine459.1GFAP, VIM, S100B
18acth459.1S100B, GFAP, SYP
19mucicarmine459.0SYP, ACTC1, VIM, S100B
20b 723459.0S100B, SYP, ACTC1, VIM
21methionine458.9GFAP, S100B, VIM
22iron45 269.8S100B, ACTC1, VIM, GFAP
23dbc-amp458.8S100B, VIM, GFAP, SYP
24nmda45 309.8SYP, GFAP, VIM
25choline45 26 1310.8VIM, GFAP, SYP, S100B
26gaba458.8VIM, S100B, GFAP, SYP
27acetylcholine45 51 30 26 1312.7GFAP, VIM, SYP, S100B
28forskolin45 51 1310.7SYP, VIM, GFAP, S100B
29leucine458.7VIM, SYP, S100B, GFAP
30cyclic amp45 269.7GFAP, S100B, SYP, VIM
31ethanol45 51 26 1311.6GFAP, S100B, SYP
32s 100458.4SYP, GFAP, VIM, ACTC1, S100B
33reticulin458.4S100B, ACTC1, GFAP, VIM, SYP
34hematoxylin458.4S100B, SYP, ACTC1, GFAP, VIM
35formaldehyde45 269.4GFAP, VIM, ACTC1, SYP, S100B
36glycogen45 269.4S100B, VIM, ACTC1, SYP, GFAP
37paraffin458.4SYP, ACTC1, VIM, GFAP, S100B
38creatinine458.4S100B, SYP, VIM, GFAP, ACTC1
39progesterone45 30 61 26 1312.4GFAP, ACTC1, SYP, S100B, VIM
40testosterone45 61 26 1311.4ACTC1, VIM, GFAP, SYP, S100B
41dexamethasone45 51 30 1311.4VIM, GFAP, S100B, SYP, ACTC1
42vegf458.4GFAP, S100B, SYP, ACTC1, VIM
43glutamine458.4S100B, VIM, GFAP, IDH1, SYP
44estrogen458.4SYP, GFAP, ACTC1, S100B, VIM
45retinoic acid45 269.4SYP, ACTC1, VIM, GFAP, S100B
46cysteine458.4VIM, GFAP, SYP, S100B
47glutamate458.3SYP, VIM, IDH1, GFAP, S100B
48tyrosine457.9S100B, SYP, ACTC1, GFAP, PTPRJ
49serine457.8PTPRJ, VIM, SYP, S100B, GFAP
50calcium45 51 26 1310.6IDH1, PTPRJ, ACTC1, GFAP, SYP, S100B

GO Terms for genes affiliated with Angiocentric Glioma

About this section

Cellular components related to Angiocentric Glioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1peroxisomeGO:00057779.5VIM, IDH1
2intermediate filamentGO:00058829.0VIM, GFAP
3extracellular vesicular exosomeGO:00700628.2ACTC1, VIM, PTPRJ, IDH1

Biological processes related to Angiocentric Glioma according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:00300499.6ACTC1, VIM
2regulation of neuronal synaptic plasticityGO:00481689.5SYP, S100B
3Bergmann glial cell differentiationGO:00600209.5VIM, GFAP
4astrocyte developmentGO:00140029.4VIM, GFAP
5intermediate filament organizationGO:00451099.4VIM, GFAP
6long-term synaptic potentiationGO:00602919.2S100B, GFAP
7negative regulation of neuron projection developmentGO:00109779.0VIM, GFAP

Molecular functions related to Angiocentric Glioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:00052009.3VIM, GFAP
2identical protein bindingGO:00428028.7S100B, SYP, VIM

Products for genes affiliated with Angiocentric Glioma

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Angiocentric Glioma

About this section
4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet