MCID: ANG050
MIFTS: 34

Angiocentric Glioma malady

Neuronal diseases, Cancer diseases, Rare diseases categories

Summaries for Angiocentric Glioma

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MalaCards based summary: Angiocentric Glioma is related to dysembryoplastic neuroepithelial tumor and oligodendroglioma. An important gene associated with Angiocentric Glioma is ACTC1 (actin, alpha, cardiac muscle 1), and among its related pathways are Striated Muscle Contraction and Nuclear signaling by ERBB4. The compounds 2-methoxyethanol and n-acetylaspartate have been mentioned in the context of this disorder. Affiliated tissues include temporal lobe and brain, and related mouse phenotypes are muscle and homeostasis/metabolism.

Aliases & Classifications for Angiocentric Glioma

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Sources:
47Orphanet, 60UMLS, 61UMLS via Orphanet
See all sources

Angiocentric Glioma, Aliases & Descriptions:

Name: Angiocentric Glioma 47 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Neuronal diseases


Characteristics (Orphanet epidemiological data):

47
angiocentric glioma:
Prevalence: <1/1000000 (Worldwide); Age of onset: All ages; Age of death: normal life expectancy


External Ids:

Orphanet47 251671
UMLS via Orphanet61 C2363903

Related Diseases for Angiocentric Glioma

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Diseases related to Angiocentric Glioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 93)
idRelated DiseaseScoreTop Affiliating Genes
1dysembryoplastic neuroepithelial tumor31.0SYP
2oligodendroglioma30.3IDH1, GFAP, SYP
3ependymoma30.1S100B, SYP, VIM, GFAP
4astrocytoma29.9IDH1, GFAP, VIM, SYP, S100B
5melanotic neuroectodermal tumor10.5SYP
6giant cell glioblastoma10.4GFAP
7choroid plexus papilloma10.4GFAP
8histiocytosis10.4S100B
9mixed glioma10.4GFAP
10papilloma10.4ACTC1
11neurilemmoma10.4GFAP
12gliomatosis cerebri10.4GFAP
13gliosarcoma10.3GFAP
14epithelioid leiomyosarcoma10.3VIM, ACTC1
15pseudosarcomatous fibromatosis10.3VIM, ACTC1
16spindle cell carcinoma10.3VIM, ACTC1
17cutaneous fibrous histiocytoma10.2ACTC1, S100B
18tubular adenocarcinoma10.2ACTC1, SYP
19endometrial stromal sarcoma10.2VIM, ACTC1
20angiomyolipoma10.2ACTC1, VIM
21fibroma10.2VIM, ACTC1
22fibromatosis10.2ACTC1, VIM
23subependymal giant cell astrocytoma10.2SYP, S100B
24olfactory neuroblastoma10.2SYP, S100B
25angiosarcoma10.2VIM, ACTC1
26sertoli cell tumor10.2VIM, SYP
27ganglioneuroblastoma10.2SYP, S100B
28abrikosov's tumor10.2VIM, ACTC1
29temporal lobe epilepsy10.2
30frontal lobe epilepsy10.2
31pilomyxoid astrocytoma10.2
32pituicytoma10.2
33binswanger's disease10.2GFAP, SYP
34central neurocytoma10.2GFAP, SYP
35syringoma10.2GFAP, S100B
36perineurioma10.2S100B, VIM
37sex cord-gonadal stromal tumor10.2VIM, S100B
38microphthalmia10.2S100B, ACTC1
39amyotrophic lateral sclerosis 110.2SYP, GFAP
40myxopapillary ependymoma10.2S100B, GFAP
41oxyphilic adenoma10.2SYP, VIM
42pineoblastoma10.2GFAP, SYP
43rhabdoid meningioma10.2VIM, GFAP
44astroblastoma10.2GFAP, VIM
45neuroendocrine tumor10.2S100B, SYP
46choroid plexus carcinoma10.2S100B, GFAP
47anaplastic ependymoma10.1GFAP, S100B
48gemistocytic astrocytoma10.1GFAP, S100B
49malignant peripheral nerve sheath tumor10.1VIM, S100B
50teratoma10.1ACTC1, GFAP

Graphical network of the top 20 diseases related to Angiocentric Glioma:



Diseases related to angiocentric glioma

Symptoms for Angiocentric Glioma

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Drugs & Therapeutics for Angiocentric Glioma

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Drug clinical trials:

Search ClinicalTrials for Angiocentric Glioma

Search NIH Clinical Center for Angiocentric Glioma

Genetic Tests for Angiocentric Glioma

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Anatomical Context for Angiocentric Glioma

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MalaCards organs/tissues related to Angiocentric Glioma:

31
Temporal lobe, Brain

Animal Models for Angiocentric Glioma or affiliated genes

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MGI Mouse Phenotypes related to Angiocentric Glioma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053697.8GFAP, PTPRJ, VIM, ACTC1
2MP:00053767.7ACTC1, VIM, PTPRJ, GFAP, IDH1
3MP:00028737.6S100B, SYP, ACTC1, PTPRJ, GFAP

Publications for Angiocentric Glioma

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Articles related to Angiocentric Glioma:

(show all 31)
idTitleAuthorsYear
1
Angiocentric glioma: a treatable cause of epilepsy: report of a rare case. (25591686)
2014
2
Angiocentric glioma: A report of nine new cases, including four with atypical histological features. (24861831)
2014
3
Angiocentric glioma: a rare intractable epilepsy-related tumour in children. (25310736)
2014
4
Angiocentric Glioma: The Infiltrative Glioma with Ependymal Differentiation. (24913299)
2014
5
Intractable epilepsy due to angiocentric glioma: A case report and minireview. (24348765)
2014
6
Well-differentiated pediatric glial neoplasms with features of oligodendroglioma, angiocentric glioma and dysembryoplastic neuroepithelial tumors: a morphological diagnostic challenge. (24448703)
2014
7
Angiocentric glioma: clinical, morphological, immunohistochemical and molecular features in three pediatric cases. (23073165)
2013
8
Angiocentric glioma. (24116979)
2013
9
The treatment of angiocentric glioma: case report and literature review. (23596378)
2013
10
Angiocentric glioma in a 4-year-old boy: imaging characteristics and review of the literature. (22226445)
2012
11
Adult-onset angiocentric glioma of epithelioid cell-predominant type of the mesial temporal lobe suggestive of a rare but distinct clinicopathological subset within a spectrum of angiocentric cortical ependymal tumors. (22151480)
2012
12
Imaging characteristics of an unusual, high-grade angiocentric glioma: a case report and review of the literature. (23378871)
2012
13
Isocitrate dehydrogenase 1 R132H mutation is not detected in angiocentric glioma. (22445362)
2012
14
Refractory temporal lobe epilepsy caused by angiocentric glioma complicated with focal cortical dysplasia: a surgical case series. (23065092)
2012
15
The high mitotic count detected by phospho-histone H3 immunostain does not alter the benign behavior of angiocentric glioma. (21892765)
2012
16
Angiocentric glioma and surrounding cortical dysplasia manifesting as intractable frontal lobe epilepsy--case report. (21785249)
2011
17
Angiocentric glioma: a clinicopathologic review of 5 tumors with identification of associated cortical dysplasia. (21809996)
2011
18
A case of angiocentric glioma with unusual clinical and radiological features. (21887397)
2011
19
Angiocentric glioma with high proliferative index: case report and review of the literature. (22075509)
2011
20
Paroxysmal ictal phonemes in a patient with angiocentric glioma. (20160231)
2010
21
Angiocentric glioma with rich blood supply. (20399664)
2010
22
Angiocentric glioma: a case report and review of the literature. (19941376)
2010
23
Angiocentric glioma: a case series. (19338465)
2009
24
Angiocentric glioma-like tumor of the midbrain. (20110754)
2009
25
Angiocentric glioma-induced seizures in a 2-year-old child. (19304961)
2009
26
Brain surface spindle cell glioma in a patient with medically intractable partial epilepsy: a variant of monomorphous angiocentric glioma? (18179412)
2008
27
Cortical ependymoma or monomorphous angiocentric glioma? (18021197)
2008
28
Angiocentric glioma: presentation of two cases with dissimilar histology. (19130736)
2008
29
Newly codified glial neoplasms of the 2007 WHO Classification of Tumours of the Central Nervous System: angiocentric glioma, pilomyxoid astrocytoma and pituicytoma. (17598825)
2007
30
Angiocentric glioma: report of clinico-pathologic and genetic findings in 8 cases. (18059228)
2007
31
Monomorphous angiocentric glioma: a distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymoma. (16215459)
2005

Variations for Angiocentric Glioma

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Expression for genes affiliated with Angiocentric Glioma

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Search GEO for disease gene expression data for Angiocentric Glioma.

Pathways for genes affiliated with Angiocentric Glioma

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Pathways related to Angiocentric Glioma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.6ACTC1, VIM
2
Show member pathways
9.3S100B, GFAP
39.3ACTC1, PTPRJ
48.9S100B, SYP, GFAP

Compounds for genes affiliated with Angiocentric Glioma

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Compounds related to Angiocentric Glioma according to GeneCards Suite gene sharing:

(show top 50)    (show all 71)
idCompoundScoreTop Affiliating Genes
12-methoxyethanol439.9ACTC1, VIM
2n-acetylaspartate439.7SYP, GFAP
34-aminopyridine43 2810.7SYP, VIM
42,3-cyclic nucleotide439.6S100B, GFAP
5retinaldehyde439.6GFAP, VIM
6l-amino acid439.5SYP, S100B
7orcein439.5ACTC1, S100B, VIM
8silicone439.4GFAP, VIM
9catecholamine439.3S100B, VIM, SYP
10streptozotocin439.3GFAP, VIM, SYP
11eosin439.2S100B, VIM, GFAP
12ganglioside439.2GFAP, SYP, VIM
135-hydroxytryptamine439.2SYP, VIM, GFAP
14matrigel439.2VIM, GFAP, ACTC1
15cocaine43 1210.1GFAP, VIM, S100B
16etoposide43 49 59 1212.1SYP, S100B, VIM
17bromodeoxyuridine439.1GFAP, VIM, S100B
18acth439.1S100B, GFAP, SYP
19mucicarmine439.0SYP, ACTC1, VIM, S100B
20b 723439.0S100B, SYP, ACTC1, VIM
21methionine438.9GFAP, S100B, VIM
22iron43 249.8S100B, ACTC1, VIM, GFAP
23dbc-amp438.8S100B, VIM, GFAP, SYP
24nmda43 289.8SYP, GFAP, VIM
25choline43 24 1210.8VIM, GFAP, SYP, S100B
26gaba438.8VIM, S100B, GFAP, SYP
27acetylcholine43 49 28 24 1212.7GFAP, VIM, SYP, S100B
28forskolin43 49 1210.7SYP, VIM, GFAP, S100B
29leucine438.7VIM, SYP, S100B, GFAP
30cyclic amp43 249.7GFAP, S100B, SYP, VIM
31ethanol43 49 24 1211.6GFAP, S100B, SYP
32s 100438.4SYP, GFAP, VIM, ACTC1, S100B
33reticulin438.4S100B, ACTC1, GFAP, VIM, SYP
34hematoxylin438.4S100B, SYP, ACTC1, GFAP, VIM
35formaldehyde43 249.4GFAP, VIM, ACTC1, SYP, S100B
36glycogen43 249.4S100B, VIM, ACTC1, SYP, GFAP
37paraffin438.4SYP, ACTC1, VIM, GFAP, S100B
38creatinine438.4S100B, SYP, VIM, GFAP, ACTC1
39progesterone43 28 59 24 1212.4GFAP, ACTC1, SYP, S100B, VIM
40testosterone43 59 24 1211.4ACTC1, VIM, GFAP, SYP, S100B
41dexamethasone43 49 28 1211.4VIM, GFAP, S100B, SYP, ACTC1
42vegf438.4GFAP, S100B, SYP, ACTC1, VIM
43glutamine438.4S100B, VIM, GFAP, IDH1, SYP
44estrogen438.4SYP, GFAP, ACTC1, S100B, VIM
45retinoic acid43 249.4SYP, ACTC1, VIM, GFAP, S100B
46cysteine438.4VIM, GFAP, SYP, S100B
47glutamate438.3SYP, VIM, IDH1, GFAP, S100B
48tyrosine437.9S100B, SYP, ACTC1, GFAP, PTPRJ
49serine437.8PTPRJ, VIM, SYP, S100B, GFAP
50calcium43 49 24 1210.6IDH1, PTPRJ, ACTC1, GFAP, SYP, S100B

GO Terms for genes affiliated with Angiocentric Glioma

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Cellular components related to Angiocentric Glioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1peroxisomeGO:00057779.5VIM, IDH1
2intermediate filamentGO:00058829.0VIM, GFAP
3extracellular vesicular exosomeGO:00700628.2ACTC1, VIM, PTPRJ, IDH1

Biological processes related to Angiocentric Glioma according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:00300499.6ACTC1, VIM
2regulation of neuronal synaptic plasticityGO:00481689.5SYP, S100B
3Bergmann glial cell differentiationGO:00600209.5VIM, GFAP
4astrocyte developmentGO:00140029.4VIM, GFAP
5intermediate filament organizationGO:00451099.4VIM, GFAP
6long-term synaptic potentiationGO:00602919.2S100B, GFAP
7negative regulation of neuron projection developmentGO:00109779.0VIM, GFAP

Molecular functions related to Angiocentric Glioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:00052009.3VIM, GFAP
2identical protein bindingGO:00428028.7S100B, SYP, VIM

Products for genes affiliated with Angiocentric Glioma

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Sources for Angiocentric Glioma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet