AILT
MCID: ANG046
MIFTS: 40

Angioimmunoblastic T-Cell Lymphoma (AILT) malady

Rare diseases, Cancer diseases, Blood diseases, Immune diseases categories
Download this MalaCard

Summaries for Angioimmunoblastic T-Cell Lymphoma

About this section
Sources:
33MalaCards
See all sources

Fully expand this MalaCard
MalaCards: Angioimmunoblastic T-Cell Lymphoma, also known as immunoblastic lymphadenopathy, is related to peripheral t-cell lymphoma and b-cell lymphomas. An important gene associated with Angioimmunoblastic T-Cell Lymphoma is TBX21 (T-box 21), and among its related pathways are Leishmaniasis and Calcineurin-regulated NFAT-dependent transcription in lymphocytes. The compound allergens have been mentioned in the context of this disorder. Affiliated tissues include t cells, b cells and bone marrow, and related mouse phenotypes are tumorigenesis and immune system.

Aliases & Classifications for Angioimmunoblastic T-Cell Lymphoma

About this section
Sources:
43NIH Rare Diseases, 45Novoseek, 49Orphanet, 62UMLS, 26ICD10 via Orphanet, 59SNOMED-CT via Orphanet, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Blood diseases, Immune diseases


Characteristics (Orphanet epidemiological data):

49
angioimmunoblastic t-cell lymphoma:
Age of onset: Adulthood


Aliases & Descriptions:

angioimmunoblastic t-cell lymphoma 43 45 49
immunoblastic lymphadenopathy 43 49
t-cell lymphoma, aild type 43 49
lymphogranulomatosis x 43 49
ailt 43 49
angioimmunoblastic lymphadenopathy 62


External Ids:

ICD10 via Orphanet26 C84.4
SNOMED-CT via Orphanet59 413537009, 835009
ICD1025 C86.5

Related Diseases for Angioimmunoblastic T-Cell Lymphoma

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Angioimmunoblastic T-Cell Lymphoma:



Diseases related to angioimmunoblastic t-cell lymphoma

Symptoms for Angioimmunoblastic T-Cell Lymphoma

About this section

Drugs & Therapeutics for Angioimmunoblastic T-Cell Lymphoma

About this section
Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
See all sources

Drug clinical trials:

Search ClinicalTrials for Angioimmunoblastic T-Cell Lymphoma

Search NIH Clinical Center for Angioimmunoblastic T-Cell Lymphoma

Genetic Tests for Angioimmunoblastic T-Cell Lymphoma

About this section

Anatomical Context for Angioimmunoblastic T-Cell Lymphoma

About this section
Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Angioimmunoblastic T-Cell Lymphoma:

33
T cells, B cells, Bone marrow, Bone, Kidney, Endothelial, Lymph node, Testes

Animal Models for Angioimmunoblastic T-Cell Lymphoma or affiliated genes

About this section
Sources:
37MGI
See all sources

MGI Mouse Phenotypes related to Angioimmunoblastic T-Cell Lymphoma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.7TBX21, PDCD1, ICOS
2MP:00053878.4TBX21, PDCD1, MAF, ICOS

Publications for Angioimmunoblastic T-Cell Lymphoma

About this section
Sources:
52PubMed
See all sources

Articles related to Angioimmunoblastic T-Cell Lymphoma:

(show top 50)    (show all 216)
idTitleAuthorsYear
1
Primary cutaneous follicular helper T-cell lymphoma treated with allogeneic bone marrow transplantation: immunohistochemical comparison with angioimmunoblastic T-cell lymphoma. (23756572)
2014
2
Angioimmunoblastic T-cell lymphoma mice model. (23026775)
2013
3
Clinical manifestation of angioimmunoblastic T-cell lymphoma with exuberant plasmacytosis. (23949915)
2013
4
A targeted mutational landscape of angioimmunoblastic T cell lymphoma. (24345752)
2013
5
Clinicopathologic characteristics of angioimmunoblastic T-cell lymphoma: analysis of the international peripheral T-cell lymphoma project. (22869878)
2013
6
Angioimmunoblastic T-cell lymphoma-associated pure red cell aplasia with abdominal pain. (23936760)
2013
7
Relapsed angioimmunoblastic T-cell lymphoma with acquired expression of CD20: a case report and review of the literature. (23738899)
2013
8
ITK/SYK translocation in angioimmunoblastic T-cell lymphoma. (24076779)
2013
9
Angioimmunoblastic T cell lymphoma in an ankylosing spondylitis patient treated with etanercept. (22791222)
2013
10
Angioimmunoblastic T Cell Lymphoma: An Unusual Presentation of Posttransplant Lymphoproliferative Disorder in a Pediatric Patient. (24157860)
2013
11
Cutaneous manifestations of angioimmunoblastic T-cell lymphoma. (23768300)
2013
12
Successful treatment with rituximab for angioimmunoblastic T-cell lymphoma. (24371775)
2013
13
Cytokine removal under hemodiafiltration with endogenous reinfusion in acute kidney injury secondary to angioimmunoblastic T-cell lymphoma: a case report. (23344085)
2012
14
Targeting intratumoral B cells with rituximab in addition to CHOP in angioimmunoblastic T-cell lymphoma. A clinicobiological study of the GELA. (22371178)
2012
15
Angioimmunoblastic T-cell lymphoma: the effect of initial treatment and microvascular density in 31 patients. (22038726)
2012
16
Bortezomib-based treatment for relapsed and refractory angioimmunoblastic T-cell lymphoma: Case report and literature review. (22844366)
2012
17
Secondary cutaneous Epstein-Barr virus-associated diffuse large B-cell lymphoma in a patient with angioimmunoblastic T-cell lymphoma: a case report and review of literature. (22260632)
2012
18
False-positive human immunodeficiency virus antibody test and autoimmune hemolytic anemia in a patient with angioimmunoblastic T-cell lymphoma. (22001471)
2011
19
Angioimmunoblastic T-cell lymphoma presenting with both IgA-related leukocytoclastic vasculitis and mucous membrane pemphigoid. (21489903)
2011
20
Angioimmunoblastic T-Cell lymphoma: a critical analysis of clinical, morphologic and immunophenotypic features. (21045384)
2010
21
Infectious mononucleosis-like lesions, a rare manifestation of angioimmunoblastic T-cell lymphoma. (20350275)
2010
22
Angioimmunoblastic T-cell lymphoma in bone marrow: a morphologic and immunophenotypic study. (19740519)
2010
23
Targeting CD52 as a novel therapeutic strategy in angioimmunoblastic T-cell lymphoma. (20795788)
2010
24
A suspicion of chikungunya leading to a diagnosis of angioimmunoblastic T-cell lymphoma. (19173091)
2009
25
No correlation between immunoglobulin heavy chain rearrangements and the prognosis of angioimmunoblastic T-cell lymphoma. (19467019)
2009
26
Germinal-center T-helper-cell markers PD-1 and CXCL13 are both expressed by neoplastic cells in angioimmunoblastic T-cell lymphoma. (19095563)
2009
27
'Precursors' of classical Hodgkin lymphoma in samples of angioimmunoblastic T-cell lymphoma. (18324974)
2008
28
Complete response of relapsed angioimmunoblastic T-cell lymphoma following therapy with bevacizumab. (18245132)
2008
29
Clinical, biologic, and pathologic features in 157 patients with angioimmunoblastic T-cell lymphoma treated within the Groupe d'Etude des Lymphomes de l'Adulte (GELA) trials. (18292286)
2008
30
Angioimmunoblastic T-cell lymphoma revealed after treatment of B-cell lymphoproliferative diseases. (18464122)
2008
31
Angioimmunoblastic T cell lymphoma: pathobiological insights and clinical implications. (17534160)
2007
32
Angioimmunoblastic T-cell lymphoma with polyclonal proliferation of plasma cells in peripheral blood and marrow. (17106190)
2007
33
Durable remission after the administration of rituximab for EBV-negative, diffuse large B-cell lymphoma following autologous peripheral blood stem cell transplantation for angioimmunoblastic T-cell lymphoma. (17325908)
2007
34
Systemic varicella zoster virus reinfection in a case of angioimmunoblastic T-cell lymphoma. (17535405)
2007
35
Successful treatment of refractory angioimmunoblastic T-cell lymphoma with thalidomide and dexamethasone. (16923528)
2006
36
Phenotype of neoplastic cells in angioimmunoblastic T-cell lymphoma is consistent with activated follicular B helper T cells. (16861359)
2006
37
Identification of circulating CD10 positive T cells in angioimmunoblastic T-cell lymphoma. (16341050)
2006
38
Fulminant Epstein-Barr virus (EBV)-associated T-cell lymphoproliferative disorder with hemophagocytosis following autologous peripheral blood stem cell transplantation for relapsed angioimmunoblastic T-cell lymphoma. (16330097)
2006
39
Expression of CXCL13 by neoplastic cells in angioimmunoblastic T-cell lymphoma (AITL): a new diagnostic marker providing evidence that AITL derives from follicular helper T cells. (16625095)
2006
40
Angioimmunoblastic T-cell lymphoma with supervening Epstein-Barr virus-associated large B-cell lymphoma. (17076535)
2006
41
Lymphocyte immunophenotype of circulating angioimmunoblastic T-cell lymphoma cells. (16803465)
2006
42
Sustained remission from angioimmunoblastic T-cell lymphoma induced by alemtuzumab. (16520806)
2006
43
Successful cidofovir therapy of progressive multifocal leukoencephalopathy preceding angioimmunoblastic T-cell lymphoma. (16334909)
2005
44
T- and B-cell clonality and frequency of human herpes viruses-6, -8 and Epstein Barr virus in angioimmunoblastic T-cell lymphoma. (16134192)
2004
45
Angioimmunoblastic T-cell lymphoma with cutaneous involvement: a case report with subtle histologic changes and clonal T-cell proliferation. (15387690)
2004
46
Angioimmunoblastic T-cell lymphoma. (12195216)
2002
47
Cutaneous involvement by angioimmunoblastic T-cell lymphoma with remarkable heterogeneous Epstein-Barr virus expression. (11493382)
2001
48
Angioimmunoblastic T-cell lymphoma (AIL-TCL) following macrolide administration. (10800250)
2000
49
Pure red cell aplasia complicated by angioimmunoblastic T-cell lymphoma: humoral factor plays a main role in the inhibition of erythropoiesis from CD34(+) progenitor cells. (10589086)
1999
50
Oligoclonal populations of T and B cells in a case of angioimmunoblastic T-cell lymphoma predominantly infiltrated by T cells of the VB5.1 family. (9208808)
1997

Variations for Angioimmunoblastic T-Cell Lymphoma

About this section

Expression for genes affiliated with Angioimmunoblastic T-Cell Lymphoma

About this section
Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Angioimmunoblastic T-Cell Lymphoma

Search GEO for disease gene expression data for Angioimmunoblastic T-Cell Lymphoma.

Pathways for genes affiliated with Angioimmunoblastic T-Cell Lymphoma

About this section
Sources:
50PathCards, 30KEGG, 38NCBI BioSystems Database, 55Reactome, 53QIAGEN
See all sources

Pathways related to Angioimmunoblastic T-Cell Lymphoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.4TBX21, MAF
2
Show member pathways
Calcium signaling in the CD4+ TCR pathway38
9.4TBX21, MAF
3
Show member pathways
BCR signaling pathway38
TCR Signaling Pathway38
9.4PDCD1, ICOS
49.4ICOS, PDCD1
5
Show member pathways
9.4PDCD1, ICOS

Compounds for genes affiliated with Angioimmunoblastic T-Cell Lymphoma

About this section
Sources:
45Novoseek
See all sources

Compounds related to Angioimmunoblastic T-Cell Lymphoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1allergens459.5PDCD1, CSTA

GO Terms for genes affiliated with Angioimmunoblastic T-Cell Lymphoma

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Angioimmunoblastic T-Cell Lymphoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098979.4PDCD1, ICOS

Biological processes related to Angioimmunoblastic T-Cell Lymphoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell-cell adhesionGO:0163379.5CSTA, ICOS
2T cell costimulationGO:0312959.1PDCD1, ICOS

Products for genes affiliated with Angioimmunoblastic T-Cell Lymphoma

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Angioimmunoblastic T-Cell Lymphoma

About this section
4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet