MCID: ANG016
MIFTS: 40

Angiokeratoma malady

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Angiokeratoma

About this section

Aliases & Descriptions for Angiokeratoma:

Name: Angiokeratoma 10 47 12 36 65
Angiokeratoma of Skin 10 65
 
Cutaneous Angiokeratoma 10
Skin Angiokeratoma 10

Classifications:



External Ids:

Disease Ontology10 DOID:479
MeSH36 D000794
SNOMED-CT59 254788004, 26810009
NCIt42 C2874, C4488
UMLS65 C0002985, C0346075

Summaries for Angiokeratoma

About this section
Wikipedia:68 Angiokeratoma is a benign cutaneous lesion of capillaries, resulting in small marks of red to blue color... more...

MalaCards based summary: Angiokeratoma, also known as angiokeratoma of skin, is related to fucosidosis and angiokeratoma of fordyce. An important gene associated with Angiokeratoma is NAGA (N-Acetylgalactosaminidase, Alpha-), and among its related pathways are Glycosphingolipid biosynthesis - globo series and Sphingolipid metabolism. Affiliated tissues include skin, breast and lung, and related mouse phenotypes are liver/biliary system and cardiovascular system.

Related Diseases for Angiokeratoma

About this section

Diseases related to Angiokeratoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 110)
idRelated DiseaseScoreTop Affiliating Genes
1fucosidosis32.1CTSA, FUCA1, NAGA
2angiokeratoma of fordyce12.2
3angiokeratoma circumscriptum12.1
4vulvar angiokeratoma12.1
5angiokeratoma of mibelli12.0
6angiokeratoma corporis diffusum with arteriovenous fistulas11.9
7fabry disease11.9
8schindler disease11.0
9mccallum macadam johnston syndrome10.9
10mantle cell lymphoma10.8MANBA, NAGA
11prolidase deficiency10.7CTSA, MANBA
12female reproductive system disease10.7HBA1, PROX1
13xanthomatosis10.7CTSA, NAGA
143-hydroxyacyl-coa dehydrogenase deficiency10.7CTSA, MANBA, NAGA
15atrial septal defect 610.7AGA, CTSA, NAGA
16capillary disease10.7CTSA, VIM
17mood disorder10.6CTSA, GLA, MANBA
18galactosialidosis10.6
19mental retardation, x-linked 10110.6FUCA1, GLA, NAGA
20kanzaki disease10.5
21spindle cell variant squamous cell breast carcinoma10.5VIM, WT1
22breast juvenile papillomatosis10.5HBA1, PROX1, WT1
23adult mesoblastic nephroma10.5VIM, WT1
24gallbladder angiosarcoma10.5CD34, HBA1
25benign fibrous mesothelioma10.4CD34, HBA1
26mucoepidermoid carcinoma10.4CD34, HBA1
27neurofibroma of the esophagus10.4CD34, HBA1
28tuberculous oophoritis10.4CD34, HBA1
29thyroid sarcoma10.4CD34, HBA1
30skin angiosarcoma10.4CD34, HBA1
31bladder urachal squamous cell carcinoma10.4FLT1, SLC2A1
32brawny scleritis10.4CD34, HBA1
33conventional angiosarcoma10.4CD34, HBA1
34littre gland carcinoma10.4CD34, HBA1
35multifocal osteogenic sarcoma10.4CD34, HBA1
36vaginal villous adenoma10.4CD34, HBA1
37middle ear disease10.3CD34, VIM
38enamel erosion10.3CD34, HBA1
39conventional fibrosarcoma10.3CD34, WT1
40acute retinal necrosis syndrome10.3SLC2A1, WT1
41male infertility10.3AGA, CTSA, FUCA1, GLA, MANBA
42dyskeratosis congenita10.2FLT1, HBA1, SLC2A1
43freemartinism10.2CD34, HBA1, WT1
44sclerosing liposarcoma10.2CD34, HBA1
45median neuropathy10.2CD34, HBA1, WT1
46integumentary system cancer10.2CD34, HBA1, SLC2A1
47leukemoid reaction10.1CD34, HBA1, SLC2A1
48uterine corpus adenocarcinofibroma10.1CD34, HBA1, VIM
49arterial tortuosity syndrome10.1CTSA, NEU3
50mushroom workers' lung10.1CD34, WT1

Graphical network of the top 20 diseases related to Angiokeratoma:



Diseases related to angiokeratoma

Symptoms for Angiokeratoma

About this section

Drugs & Therapeutics for Angiokeratoma

About this section

Interventional clinical trials:

idNameStatusNCT IDPhase
1Fabry Disease RegistryRecruitingNCT00196742
2Fabry's Disease and Pregnancy (PREFAB)Enrolling by invitationNCT02582294
3Enzyme Replacement Therapy in Fabry DiseaseTerminatedNCT00149318

Search NIH Clinical Center for Angiokeratoma


Cochrane evidence based reviews: angiokeratoma

Genetic Tests for Angiokeratoma

About this section

Anatomical Context for Angiokeratoma

About this section

MalaCards organs/tissues related to Angiokeratoma:

33
Skin, Breast, Lung, Tongue, Endothelial, Prostate, Bone

Animal Models for Angiokeratoma or affiliated genes

About this section

MGI Mouse Phenotypes related to Angiokeratoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053709.1AGA, CTSA, GLA, MANBA, PROX1, SELL
2MP:00053857.2CTSA, FLT1, GLA, MANBA, PDPN, PROX1
3MP:00053867.1AGA, CTSA, CTSB, FA2H, FLT1, GLA
4MP:00053846.9AGA, CD34, CTSA, CTSB, FLT1, GLA
5MP:00053976.7CD34, CTSA, FLT1, MANBA, MRAS, PDPN
6MP:00053786.7AGA, CTSA, CTSB, FLT1, GLA, PDPN
7MP:00053875.8CD34, CTSA, CTSB, FLT1, GLA, MANBA
8MP:00053765.1AGA, CD34, CTSA, CTSB, FA2H, FLT1

Publications for Angiokeratoma

About this section

Articles related to Angiokeratoma:

(show top 50)    (show all 348)
idTitleAuthorsYear
1
Solitary Angiokeratoma Presenting as Cutaneous Horn over the Prepuce: A Rare Appearance. (27057048)
2016
2
Thrombotic phenomena in angiokeratoma can evolve into spontaneous involution of the lesions: a report of two cases. (26395775)
2015
3
Angiokeratoma of the nasal vestibule: a case report. (25547753)
2014
4
Angiokeratoma of vulva mimicking genital warts. (25404845)
2014
5
Angiokeratoma circumscriptum of the buccal mucosa: a case report and literature review. (25368837)
2014
6
Treatment of angiokeratoma of Mibelli alone or in combination with pulsed dye laser and long-pulsed Nd: YAG laser. (24911941)
2014
7
A case of solitary angiokeratoma successfully treated with a 1064-nm long-pulsed Nd:YAG laser. (25260142)
2014
8
Angiokeratoma circumscriptum neviforme: An entity, few and far between. (25396132)
2014
9
Angiokeratoma corporis diffusum in a patient with Hodgkin lymphoma: a new paraneoplastic skin manifestation? (23278357)
2013
10
Enzyme replacement therapy in two Japanese siblings with Fabry disease, and its effectiveness on angiokeratoma and neuropathic pain. (23906479)
2013
11
Angiokeratoma presenting as a melanoma: a case report. (23697732)
2013
12
Angiokeratoma - When is a few too many? (24104692)
2013
13
Solitary angiokeratoma on palms and soles: a clinicopathological analysis of 21 cases. (23734792)
2013
14
Concurrent diagnosis of vulvar angiokeratoma with recurrent squamous cell carcinoma after radical vulvectomy and radiation therapy. (24371626)
2012
15
Myoclonus and angiokeratomas in adult galactosialidosis. (21312277)
2011
16
Angiokeratoma of the vulva. (22053688)
2011
17
Report of two angiokeratoma of Fordyce cases treated with a 1064 nm long-pulsed Nd:YAG laser. (19439000)
2009
18
Angiokeratoma of clitoris: a rare lesion in an adolescent girl. (18291515)
2008
19
Treatment of angiokeratoma of Fordyce with pulsed dye laser. (16970695)
2006
20
Angiokeratoma Fordyce of the glans penis: combined treatment with erbium: YAG and 532 nm KTP (frequency doubled neodynium: YAG) laser. (15729872)
2004
21
Linear acral pseudolymphomatous angiokeratoma of children (APACHE): further evidence that APACHE is a cutaneous pseudolymphoma. (12582375)
2003
22
Vulvar angiokeratoma following radical hysterectomy and radiotherapy. (12027822)
2002
23
Comments on angiokeratoma of the tongue. (17656958)
2002
24
Severe predominantly acral variant of angiokeratoma of Mibelli: response to long-pulse Nd:YAG (1064 nm) laser treatment. (11606931)
2001
25
Angiokeratoma circumscriptum naeviforme: rare presentation on the neck. (11903167)
2001
26
Angiokeratoma of the oral cavity and scrotum. (10721665)
2000
27
Idiopathic angiokeratoma corporis diffusum. (9499615)
1997
28
Laser treatment of recurrent vulvar angiokeratoma associated with Noonan syndrome. (8677117)
1996
29
Angiokeratoma corporis diffusum with glycopeptiduria due to deficient lysosomal alpha-N-acetylgalactosaminidase activity. Clinical, morphologic, and biochemical studies. (8466216)
1993
30
Transepidermal elimination of thrombi in three cases of thrombotic angiokeratoma: an incidental histopathologic finding of angiokeratoma. (1791241)
1991
31
Biochemical and clinical analysis of accumulated glycolipids in symptomatic heterozygotes of angiokeratoma corporis diffusum (Fabry's disease) in comparison with hemizygotes. (2157788)
1990
32
Anderson-Fabry disease (angiokeratoma corporis diffusum universale). (2123167)
1990
33
Angiokeratoma of the vulva: diagnosis and review of the literature. (2657519)
1989
34
Ultrastructure of angiokeratoma vulvae. (2449019)
1988
35
Angiokeratoma circumscriptum of the index finger in a child. (7465672)
1981
36
Diffuse angiokeratoma (Fabry's disease): Case report. (817232)
1976
37
A case of angiokeratoma corporis circumscriptum neviforme. (811697)
1975
38
Angiokeratoma "Circumscriptum". (4639261)
1972
39
Angiokeratoma of Mibelli with necrosis of the fingertips. (4635805)
1972
40
Angiokeratoma of the vulva. (5479313)
1970
41
Angiokeratoma of Mibelli: a family with nodular lesions of the legs. (5708572)
1968
42
Angiokeratoma corporis diffusum--Fabry's disease. (5592081)
1967
43
Angiokeratoma corporis diffusum. (5960367)
1966
44
The ocular manifestations of hereditary dystopic lipidosis (angiokeratoma corporis diffusum universale). (13990468)
1963
45
Angiokeratoma corporis diffusum. (13781480)
1960
46
Angiokeratoma corporis diffusum. (13584689)
1958
47
Histological investigation of the skin in angiokeratoma corporis diffusum in particular with regard to the associated disturbance of phosphatid metabolism. (13219963)
1954
48
Angiomas of the scrotum (angiokeratoma, Fordyce); compilation of cases and discussion of nomenclature. (20277301)
1946
49
Angiokeratoma, with Bony Changes. (19977542)
1914
50

Variations for Angiokeratoma

About this section

Expression for genes affiliated with Angiokeratoma

About this section
Search GEO for disease gene expression data for Angiokeratoma.

Pathways for genes affiliated with Angiokeratoma

About this section

Pathways related to Angiokeratoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
110.1GLA, NAGA
2
Show member pathways
9.2CTSA, FA2H, GLA, NEU3
38.8AGA, CTSA, CTSB, FUCA1, GLA, MANBA
4
Show member pathways
8.7AGA, FUCA1, FUCA2, MANBA, NEU3

GO Terms for genes affiliated with Angiokeratoma

About this section

Cellular components related to Angiokeratoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1caveolaGO:00059019.7CTSB, SLC2A1
2lysosomeGO:00057649.6AGA, CTSA, MANBA

Biological processes related to Angiokeratoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1proteolysis involved in cellular protein catabolic processGO:00516039.9CTSA, CTSB

Sources for Angiokeratoma

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet