Angiomatosis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: ANG037 MIFTS: 37	Angiomatosis malady
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Aliases & Classifications for Angiomatosis

Aliases & Descriptions for Angiomatosis:

Name: Angiomatosis ⁵¹ ⁵² ⁶⁹

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Summaries for Angiomatosis

NINDS : ⁵¹ Von Hippel-Lindau disease (VHL) is a rare, genetic multi-system disorder in which non-cancerous tumors grow in certain parts of the body. Slow-growing hemgioblastomas -- benign tumors with many blood vessels -- may develop in the brain, spinal cord, the retinas of the eyes, and near the inner ear. Cysts (fluid-filled sacs) may develop around the hemangioblastomas. Other types of tumors develop in the adrenal glands, the kidneys, or the pancreas. Symptoms of VHL vary among individuals and depend on the size and location of the tumors. Symptoms may include headaches, problems with balance and walking, dizziness, weakness of the limbs, vision problems, deafness in one ear, and high blood pressure. Individuals with VHL are also at a higher risk than normal for certain types of cancer, especially kidney cancer.

MalaCards based summary : Angiomatosis is related to hemopneumothorax and hypomelanosis of ito. An important gene associated with Angiomatosis is VHL (Von Hippel-Lindau Tumor Suppressor), and among its related pathways/superpathways is PI3K-Akt signaling pathway. The drugs Miconazole and Everolimus have been mentioned in the context of this disorder. Affiliated tissues include brain, kidney and retina, and related phenotypes are Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection after viral supernatant infection and cardiovascular system

Wikipedia : ⁷¹ Angiomatosis is a non-neoplastic condition presenting with little knots of capillaries in various... more...

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Related Diseases for Angiomatosis

Diseases related to Angiomatosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 141)

id	Related Disease	Score	Top Affiliating Genes
1	hemopneumothorax	29.5	IFNA2 VHL
2	hypomelanosis of ito	28.4	FLT4 GALNT3 GLMN GYS1 IFNA2 PROX1
3	bacillary angiomatosis	12.2
4	diffuse dermal angiomatosis	12.2
5	skeletal-extraskeletal angiomatosis	11.9
6	breast angiomatosis	11.9
7	familial capillaro-venous leptomeningeal angiomatosis	11.9
8	angiomatosis, leptomeningeal capillary venous	11.8
9	sturge-weber syndrome, somatic, mosaic	11.8
10	angiomatosis, diffuse corticomeningeal, of divry and van bogaert	11.8
11	cystic angiomatosis of bone, diffuse	11.7
12	cobb syndrome	11.2
13	bartonellosis	11.1
14	gorham's disease	11.0
15	von hippel-lindau syndrome	11.0
16	multiple enchondromatosis, maffucci type	10.7
17	multifocal lymphangioendotheliomatosis with thrombocytopenia	10.7
18	multiple mitochondrial dysfunctions syndrome 1	10.2	CCL26 TSC2
19	blue color blindness	10.2	CD4 IFNA2
20	fallopian tube adenofibroma	10.2	GNAQ IFNA2
21	stromal corneal pigmentation	10.2	CD4 IFNA2
22	retinitis	10.2
23	weber syndrome	10.1
24	facial nerve disease	10.1	GNAQ IFNA2
25	sarcoma	10.1
26	hydronephrosis	10.1	ATR CD4 CERKL
27	lysteria monocytoigeneses meningitis	10.1	FLT4 PROX1
28	oculodentodigital dysplasia	10.1	FLT4 PROX1
29	chromosome 18 pericentric inversion	10.1	FLT4 PROX1
30	cat-scratch disease	10.0
31	acrofacial dysostosis, patagonia type	10.0	FLT4 PROX1
32	benign familial neonatal epilepsy	10.0	FLT4 IFNA2 PROX1
33	weyers ulnar ray/oligodactyly syndrome	10.0	FLT4 GLMN GNAQ
34	acquired immunodeficiency syndrome	10.0
35	ovarian brenner tumor	9.9	FLT4 IFNA2 TSC2 VHL
36	cerebritis	9.9
37	keratosis follicularis spinulosa decalvans	9.9	FLT4 PROX1
38	saethre-chotzen syndrome	9.9	CD4 FLT4 IFNA2
39	leukemia	9.9
40	thrombocytopenia	9.9
41	meningitis	9.9
42	atherosclerosis	9.8
43	hepatitis	9.8
44	endotheliitis	9.8
45	bacteremia	9.8
46	chronic lymphocytic leukemia	9.8
47	mediastinitis	9.8
48	calciphylaxis	9.7
49	pancreatitis	9.7
50	pyogenic granuloma	9.7

Graphical network of the top 20 diseases related to Angiomatosis:

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Symptoms & Phenotypes for Angiomatosis

GenomeRNAi Phenotypes related to Angiomatosis according to GeneCards Suite gene sharing:

²⁶

id	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection after viral supernatant infection	GR00233-A-3	8.92	CCL26 FLT4 MED12 PROX1

MGI Mouse Phenotypes related to Angiomatosis:

⁴⁴

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	cardiovascular system	MP:0005385	10.17	FLT4 PROX1 GALNT3 ATR GLMN GNAQ
2	cellular	MP:0005384	10.1	DLK1 MED12 GLMN ATR CD4 CERKL
3	growth/size/body region	MP:0005378	10.07	MED12 FLT4 PLAG1 PROX1 GALNT3 ATR
4	embryo	MP:0005380	9.97	DLK1 MED12 PLAG1 FLT4 ATR GLMN
5	endocrine/exocrine gland	MP:0005379	9.92	PLAG1 GALNT3 ATR GNAQ CD4 PROX1
6	homeostasis/metabolism	MP:0005376	9.9	DLK1 FLT4 GALNT3 GLMN ATR GNAQ
7	liver/biliary system	MP:0005370	9.5	FLT4 PROX1 ATR GYS1 DLK1 TSC2
8	normal	MP:0002873	9.23	MED12 FLT4 ATR GNAQ CD4 PROX1

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Drugs & Therapeutics for Angiomatosis

Drugs for Angiomatosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 43)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Miconazole

Approved, Investigational, Vet_approved

Phase 2, Phase 3

22916-47-8

4189

Everolimus

Approved

Phase 2, Phase 3

159351-69-6

6442177

Sirolimus

Approved, Investigational

Phase 2, Phase 3

53123-88-9

5284616 6436030 46835353

Anti-Bacterial Agents

Phase 2, Phase 3

Anti-Infective Agents

Phase 2, Phase 3

Immunosuppressive Agents

Phase 2, Phase 3

Antifungal Agents

Phase 2, Phase 3

Antibiotics, Antitubercular

Phase 2, Phase 3

Pharmaceutical Solutions

Phase 2, Phase 3,Phase 1

Sunitinib

Approved, Investigational

Phase 2,Phase 1

341031-54-7, 557795-19-4

5329102

Ranibizumab

Approved

Phase 1, Phase 2

347396-82-1

459903

Somatostatin

Approved

Phase 2

38916-34-6, 51110-01-1

53481605

Pancrelipase

Approved

Phase 2

53608-75-6

Vatalanib

Investigational

Phase 2

212141-54-3

151194

Angiogenesis Inhibitors

Phase 2,Phase 1,Early Phase 1

Angiogenesis Modulating Agents

Phase 2,Phase 1,Early Phase 1

Fluorodeoxyglucose F18

Phase 2

Protein Kinase Inhibitors

Phase 2

Radiopharmaceuticals

Phase 2

Anticonvulsants

Phase 1, Phase 2

pancreatin

Phase 2

histidine

Nutraceutical

Phase 1, Phase 2

Bevacizumab

Approved, Investigational

Phase 1,Early Phase 1

216974-75-3

Timolol

Approved

Phase 1

26839-75-8

33624 5478

Vorinostat

Approved, Investigational

Phase 1

149647-78-9

5311

Maleic acid

Experimental

Phase 1

110-16-7

444266

Immunoglobulins

Phase 1

Antibodies, Monoclonal

Phase 1

Antibodies

Phase 1

Adrenergic Agents

Phase 1

Adrenergic Antagonists

Phase 1

Neurotransmitter Agents

Phase 1

Adrenergic beta-Antagonists

Phase 1

Tetrahydrozoline

Phase 1

Ophthalmic Solutions

Phase 1

Anti-Arrhythmia Agents

Phase 1

Antihypertensive Agents

Phase 1

Lubricant Eye Drops

Phase 1

Histone Deacetylase Inhibitors

Phase 1

Mitogens

Dermatologic Agents

Endothelial Growth Factors

GTPase-Activating Proteins

Interventional clinical trials:

(show all 41)

id	Name	Status	NCT ID	Phase
1	Trial of Sirolimus for Cognitive Impairment in Sturge-Weber Syndrome	Recruiting	NCT03047980	Phase 2, Phase 3
2	Study of Sunitinib in Patients With Von Hippel-Lindau (VHL) Disease	Completed	NCT01168440	Phase 2
3	Treatment of Von Hippel-Lindau (VHL)-Related Hemangioblastoma With PTK787/ZK 222584	Completed	NCT00052013	Phase 2
4	Treatment of Exudative and Vasogenic Chorioretinal Diseases Including Variants of AMD and Other CNV Related Maculopathy	Completed	NCT00470977	Phase 1, Phase 2
5	Efficacy and Safety Study of Topical Rapamycin Associated With Pulsed Dye Laser in Patients With Sturge-Weber Syndrome	Completed	NCT02080624	Phase 2
6	Phase II Study of Vandetanib in Individuals With Kidney Cancer	Completed	NCT00566995	Phase 2
7	17AAG to Treat Kidney Tumors in Von Hippel-Lindau Disease	Completed	NCT00088374	Phase 2
8	A Phase I/II Trial for Intravitreous Treatment of Severe Ocular Von Hippel-Lindau Disease Using a Combination of the PDGF Antagonist E10030 and the VEGF Antagonist Ranibizumab	Recruiting	NCT02859441	Phase 1, Phase 2
9	PT2385 for the Treatment of Von Hippel-Lindau Disease-Associated Clear Cell Renal Cell Carcinoma	Recruiting	NCT03108066	Phase 2
10	Evaluation of 68Gallium-DOTATATE PET/CT for Detecting Neuroendocrine Tumors	Recruiting	NCT01967537	Phase 2
11	Pazopanib in Von Hippel-Lindau (VHL) Syndrome	Active, not recruiting	NCT01436227	Phase 2
12	Cannabidiol Expanded Access Study in Medically Refractory Sturge-Weber Syndrome	Active, not recruiting	NCT02332655	Phase 1, Phase 2
13	TKI 258 in Von Hippel-Lindau Syndrome (VHL)	Terminated	NCT01266070	Phase 2
14	Sunitinib Malate to Treat Advanced Eye Disease in Patients With Von Hippel-Lindau Syndrome	Terminated	NCT00673816	Phase 1, Phase 2
15	Evaluation of Sunitinib Malate in Patients With Von Hippel-Lindau Syndrome (VHL) Who Have VHL Lesions to Follow	Terminated	NCT00330564	Phase 2
16	Adjunctive Everolimus (RAD 001) Therapy for Epilepsy in Children With Sturge-Weber Syndrome (SWS)	Withdrawn	NCT01997255	Phase 2
17	EYE001 to Treat Retinal Tumors in Patients With Von Hippel-Lindau Syndrome	Completed	NCT00056199	Phase 1
18	Ranibizumab Injections to Treat Retinal Tumors in Patients With Von Hippel-Lindau Syndrome	Completed	NCT00089765	Phase 1
19	Use of the Atkins Diet for Children With Sturge Weber Syndrome	Completed	NCT00639730	Phase 1
20	Treatment of Port-wine Mark in Sturge-Weber Syndrome Using Topical Timolol	Recruiting	NCT01533376	Phase 1
21	Effect of Vorinostat on Nervous System Hemangioblastomas in Von Hippel-Lindau Disease (Missense Mutation Only)	Enrolling by invitation	NCT02108002	Phase 1
22	Incidence of Hepatic Hemangiomatosis in Patients With Cutaneous Hemangiomas	Completed	NCT00374335
23	Hemangioma Associated With High Rates of Morbidity	Completed	NCT00394888
24	Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors	Completed	NCT00001668
25	Biomarker Development in Sturge-Weber Syndrome	Completed	NCT01345305
26	Visualizing Vascular Endothelial Growth Factor (VEGF) Producing Lesions in Von Hippel-Lindau Disease	Completed	NCT00970970
27	Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS)	Completed	NCT00610402
28	Genetic Study to Identify Gene Mutations in Participants Previously Enrolled in Clinical Trial NCI-99-C-0053 Who Have Von Hippel-Lindau Syndrome or Are at Risk for Von Hippel-Lindau Syndrome	Completed	NCT00075348
29	Registry for Vascular Anomalies Associated With Coagulopathy	Recruiting	NCT00576888
30	Screening for Endolymphatic Sac Tumours (ELSTs) in Von Hippel-Lindau (vHL) Patients	Recruiting	NCT02420067
31	Natural History and Management of Pancreatic Lesions in Von Hippel-Lindau Disease	Recruiting	NCT00062166
32	Familial Investigations of Childhood Cancer Predisposition	Recruiting	NCT03050268
33	Lymphatic Anomalies Registry	Recruiting	NCT02399527
34	National Eye Institute Biorepository for Retinal Diseases	Recruiting	NCT01496625
35	Innovative Approaches to Gauge Progression of Sturge-Weber Syndrome	Recruiting	NCT01425944
36	Von Hippel-Lindau Disease Genetic Epidemiology Study	Active, not recruiting	NCT00001803
37	Psychosocial Consequences of the Screening of Von Hippel Lindau Diseases for Patients Operated for a hémangioblastoma of Nervous Centrasl System	Active, not recruiting	NCT02120040
38	French National Cohort of Children With Port Wine Stain	Active, not recruiting	NCT01364857
39	Study of Brain and Spinal Cord Tumor Growth and Cyst Development in Patients With Von Hippel Lindau Disease	Active, not recruiting	NCT00005902
40	Assessment of Residual VHL Function in Tumors - Can it Predict the Patients' Individual Course of Disease?	Enrolling by invitation	NCT02207686
41	Bevacizumab (Avastin) in Unresectable/Recurrent Hemangioblastoma From Von-Hippel-Lindau Disease	Terminated	NCT01015300	Early Phase 1

Search NIH Clinical Center for Angiomatosis

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Genetic Tests for Angiomatosis

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Anatomical Context for Angiomatosis

MalaCards organs/tissues related to Angiomatosis:

³⁹

Brain, Kidney, Retina, Spinal Cord, Eye, Adrenal Gland, Pancreas

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Publications for Angiomatosis

Articles related to Angiomatosis:

(show top 50) (show all 545)

id	Title	Authors	Year
1	Obscure Overt Gastrointestinal Bleeding Due To Isolated Small Bowel Angiomatosis. ( 27144197 )	El Hajj I.I....Cote G.A.	2016
2	Bacillary angiomatosis presenting with facial tumor and multiple abscesses: A case report. ( 27428207 )	Markowicz M....Rieger A.	2016
3	Diffuse Dermal Angiomatosis of the Breast With an Apparent Etiology of Underlying Calcified Thrombosed Artery With Adjacent Fat Necrosis. ( 27097335 )	Strausburg M.B....Warren S.	2016
4	Bacillary angiomatosis presenting with polymorphic skin lesions. ( 27752473 )	Claasens S....Schneider J.W.	2016
5	Bullous erythema ab igne with cutaneous reactive angiomatosis. ( 27226050 )	Hirohata A....Ikegami R.	2016
6	Endothelial chimerism in chronic sclerotic-type chronic Graft-versus-Host disease and GVHD-associated angiomatosis. ( 26875995 )	Kaffenberger B.H....Gru A.A.	2016
7	Angiomatosis dAcrmica difusa de la mama: aportaciA^n de un nuevo caso en paciente no fumadora. ( 27617469 )	Delgado-Marquez A.M....Lopez-Gomez S.	2016
8	Graft-versus-host Disease-associated Angiomatosis Treated With Topical Timolol Solution. ( 27191176 )	Bashline B.R....Fivenson D.	2016
9	Successful treatment of bacillary angiomatosis with oral doxycycline in an HIV-infected child with skin lesions mimicking Kaposi sarcoma. ( 27051835 )	Rodriguez O....Kovarik C.L.	2016
10	Persistent cutaneous abdominal ulcerations secondary to diffuse dermal angiomatosis: an underestimated sign for severe atherosclerosis: A case report. ( 27442644 )	GarcA-a-Colmenero L....Pujol R.M.	2016
11	Diffuse Dermal Angiomatosis: A Clue to the Diagnosis of Atherosclerotic Vascular Disease. ( 26120304 )	Sriphojanart T....Vachiramon V.	2015
12	Imaging features of systemic cystic angiomatosis. ( 26141486 )	Marraoui W....Soubrier M.	2015
13	Cutaneous bacillary angiomatosis due to Bartonella quintana in a renal transplant recipient. ( 25652715 )	Orsag J....Zadrazil J.	2015
14	Diffuse dermal angiomatosis of the abdomen. ( 26066057 )	Lora V....Cerroni L.	2015
15	Diffuse dermal angiomatosis associated with severe atherosclerosis: two cases and review of the literature. ( 25639294 )	Crickx E....Rybojad M.	2015
16	Bacillary Angiomatosis in Immunocompetent Patient with Atypical Manifestations. ( 26538736 )	Iraji F....Rajabi P.	2015
17	Diffuse dermal angiomatosis: a clinical mimicker of vasculitis associated with calciphylaxis and monoclonal gammopathy. ( 25502367 )	Ferreli C....Rongioletti F.	2015
18	Mediastinal angiomatosis: a rare case report. ( 26793386 )	Pak M.G....Roh M.S.	2015
19	Diffuse dermal angiomatosis of the breast: a series of 22 cases from a single institution. ( 26645009 )	Reusche R....Lemaine V.	2015
20	Leptomeningeal Angiomatosis in a Case of Neurofibromatosis Type 2: An Unusual Finding. ( 26510155 )	Naik S....Phadke R.V.	2015
21	Pneumothorax-associated fibroblastic lesion in combination with localized pleural angiomatosis: A possible cause of juvenile spontaneous hemopneumothorax. ( 25749626 )	Roncati L....Maiorana A.	2015
22	Bacillary angiomatosis presenting as a digital ulcer. ( 25994885 )	Alves J.V....Fernandes BA!rtolo E.A.	2015
23	Bacillary angiomatosis: A rare finding in the setting of antiretroviral drugs. ( 26636153 )	Madua M.C.	2015
24	Vaginal angiomatosis: differential diagnosis of a rare case. ( 26401116 )	Grauso F....Messalli E.M.	2015
25	Wyburn-Mason Syndrome Associated With Cutaneous Reactive Angiomatosis and Central Retinal Vein Occlusion. ( 26247458 )	Callahan A.B....Eliott D.	2015
26	Letter to the Editor Regarding Sturge-Weber Syndrome (Encephalotrigeminal Angiomatosis): Recent Advances and Future Challenges. ( 26147014 )	Ball K.L.	2015
27	Pulmonary manifestation of a condition resembling Kasabach-Merritt syndrome in a woman with abdominal angiomatosis associated with consumptive coagulopathy--surgical management: a case report. ( 25956942 )	Cheufou D.H....Stamatis G.	2015
28	Angiomatosis: A Rare Vascular Proliferation of Head and Neck Region. ( 26157312 )	Khan S....Neogi S.	2015
29	Diffuse Breast Angiomatosis With Involvement ofA Overlying Skin: A Case Report. ( 26456034 )	Natsiopoulos I....Zaramboukas T.	2015
30	Bacillary Angiomatosis Masquerading as Kaposi Sarcoma in East Africa. ( 24718378 )	Forrestel A.K....Amerson E.H.	2014
31	Bacillary angiomatosis in a HIV-positive patient with poor adherence to antiretroviral therapy. ( 25580791 )	Lopes L....Filipe P.	2014
32	Mediastinal angiomatosis. ( 25193206 )	Tseng Y.C....Pan C.C.	2014
33	Diffuse angiomatosis of the breast--sonographic appearance. ( 24965677 )	Ciurea A....Crisan D.	2014
34	Cutaneovisceral angiomatosis with thrombocytopenia without cutaneous involvement. ( 25088066 )	Uller W....Alomari A.I.	2014
35	Tumoral bacillary angiomatosis in a child with human immunodeficiency virus. ( 25076357 )	Wanat K.A....Kovarik C.L.	2014
36	A case of bacillary angiomatosis in a patient with pancreatic adenocarcinoma. ( 24588271 )	Blattner C....Elston D.M.	2014
37	Sturge-Weber Syndrome (Encephalotrigeminal Angiomatosis): Recent Advances and Future Challenges. ( 26107979 )	Maslin J.S....Ritch R.	2014
38	Bacillary angiomatosis. ( 25187668 )	MejA-a F....Seas C.	2014
39	Propranolol for cerebral cavernous angiomatosis: a magic bullet. ( 23804539 )	Berti I....Ventura A.	2014
40	Graft-versus-host disease-associated angiomatosis: a clinicopathologically distinct entity. ( 24993601 )	Kaffenberger B.H....Cowen E.W.	2014
41	Cutaneous reactive angiomatosis with foreign body reaction after total knee replacement with a defective implant: a diagnostic challenge with a review of the literature. ( 24635713 )	Tang M.M....Borradori L.	2014
42	Diffuse dermal angiomatosis: a contributory factor to ulceration in a patient with renal transplant. ( 25265928 )	Ormerod E....Kennedy C.T.	2014
43	Dental management in an encephalotrigeminal angiomatosis patient: a case report. ( 25284546 )	Prashanthi C....Majumdar K.	2014
44	Diffuse dermal angiomatosis of the breast: Clinicopathologic study of 5 patients. ( 25264238 )	Tollefson M.M....Bridges A.G.	2014
45	Cystic bone angiomatosis: a case report treated with aminobisphosphonates and review of the literature. ( 23836156 )	Marcucci G....Brandi M.L.	2013
46	Bacillary Angiomatosis in Patients With Cancer: A Pediatric Case Report and a Review of the Literature. ( 26619465 )	McElroy A.K....Cooper T.M.	2013
47	Angiomatosis of the thoracic wall. ( 21773787 )	Stojsic J....Jovanovic J.	2013
48	Cutaneous reactive angiomatosis associated with erythema ab igne. ( 24266664 )	Palmer M.J....O'Keefe R.	2013
49	Progressive late-onset of cutaneous angiomatosis as possible sign of cerebral cavernous malformations. ( 23473272 )	Campione E....Bianchi L.	2013
50	Multi-system progressive angiomatosis in a dog resembling blue rubber bleb nevus syndrome in humans. ( 23496103 )	Ide K....Nishifuji K.	2013

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Genes for Angiomatosis

Genes related to Angiomatosis (0 elite genes):

(show all 18)

- Elite gene

- Cancer Census gene in COSMIC

id	Symbol	Description	Score	Implication	PubmedIds
1	VHL	Von Hippel-Lindau Tumor Suppressor	32.69	Novoseek inferred ⁵² GeneCards inferred via : Disorders Publications (show sections)	7670659
2	CCL26	C-C Motif Chemokine Ligand 26	26.87	GeneCards inferred via : Disorders Publications (show sections)
3	DLK1	Delta Like Non-Canonical Notch Ligand 1	26.87	GeneCards inferred via : Disorders Publications (show sections)
4	TSC2	Tuberous Sclerosis 2	26.87	GeneCards inferred via : Disorders Publications (show sections)
5	GNAQ	G Protein Subunit Alpha Q	18.48	GeneCards inferred via : Disorders (show sections)
6	ATR	ATR Serine/Threonine Kinase	17.93	GeneCards inferred via : Disorders (show sections)
7	CERKL	Ceramide Kinase Like	17.93	GeneCards inferred via : Disorders (show sections)
8	IFNA2	Interferon Alpha 2	17.93	GeneCards inferred via : Disorders (show sections)
9	PROX1	Prospero Homeobox 1	17.93	GeneCards inferred via : Disorders (show sections)
10	MED12	Mediator Complex Subunit 12	17.93	GeneCards inferred via : Disorders (show sections)
11	SLC35G5	Solute Carrier Family 35 Member G5	17.93	GeneCards inferred via : Disorders (show sections)
12	GLMN	Glomulin, FKBP Associated Protein	17.93	GeneCards inferred via : Disorders (show sections)
13	CD4	CD4 Molecule	17.93	GeneCards inferred via : Disorders (show sections)
14	GALNT3	Polypeptide N-Acetylgalactosaminyltransferase 3	17.93	GeneCards inferred via : Disorders (show sections)
15	FLT4	Fms Related Tyrosine Kinase 4	17.93	GeneCards inferred via : Disorders (show sections)
16	AKR1C2	Aldo-Keto Reductase Family 1 Member C2	17.93	GeneCards inferred via : Disorders (show sections)
17	GYS1	Glycogen Synthase 1	17.93	GeneCards inferred via : Disorders (show sections)
18	PLAG1	PLAG1 Zinc Finger	16.87	GeneCards inferred via : Disorders Publications (show sections)

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Variations for Angiomatosis

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Expression for Angiomatosis

Search GEO for disease gene expression data for Angiomatosis.

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Pathways for Angiomatosis

Pathways related to Angiomatosis according to GeneCards Suite gene sharing:

id	Super pathways	Score	Top Affiliating Genes
1	PI3K-Akt signaling pathway ³⁷	11.46	FLT4 GYS1 IFNA2 TSC2

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GO Terms for Angiomatosis

Biological processes related to Angiomatosis according to GeneCards Suite gene sharing:

id	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of transcription, DNA-templated	GO:0045893	9.8	CD4 IFNA2 MED12 PROX1 VHL
2	lymph vessel development	GO:0001945	9.37	FLT4 PROX1
3	neural tube closure	GO:0001843	9.33	GLMN MED12 TSC2
4	lymphangiogenesis	GO:0001946	9.32	FLT4 PROX1
5	positive regulation of interleukin-2 biosynthetic process	GO:0045086	9.26	CD4 GLMN
6	heart development	GO:0007507	9.26	GNAQ GYS1 MED12 TSC2
7	positive regulation of endothelial cell proliferation	GO:0001938	8.8	CCL26 FLT4 PROX1

Sources

Sources for Angiomatosis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ ExPASy

¹⁷ FDA Approved Drugs

¹⁸ FMA

¹⁹ GeneAnalytics

²⁰ GeneCards

²¹ GeneGo (Thomson Reuters)

²² GeneHancer via GeneCards

²³ GeneReviews

²⁴ GeneTests

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MeSH

⁴³ MESH via Orphanet

⁴⁴ MGI

⁴⁵ NCBI Bookshelf

⁴⁶ NCI

⁴⁷ NCIt

⁴⁸ NDF-RT

⁴⁹ NIH Clinical Center

⁵⁰ NIH Rare Diseases

⁵¹ NINDS

⁵² Novoseek

⁵³ Novus Biologicals

⁵⁴ OMIM

⁵⁵ OMIM via Orphanet

⁵⁶ Orphanet

⁵⁷ PathCards

⁵⁸ PharmGKB

⁵⁹ PubMed

⁶⁰ QIAGEN

⁶¹ R&D Systems

⁶² Reactome

⁶³ Sino Biological

⁶⁴ SNOMED-CT

⁶⁵ SNOMED-CT via Orphanet

⁶⁶ UniProtKB/Swiss-Prot

⁶⁷ TGDB

⁶⁸ Tocris

⁶⁹ UMLS

⁷⁰ UMLS via Orphanet

⁷¹ Wikipedia

Angiomatosis malady

Aliases & Classifications for Angiomatosis

Aliases & Descriptions for Angiomatosis:

Summaries for Angiomatosis

Related Diseases for Angiomatosis

Diseases related to Angiomatosis via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Angiomatosis:

Symptoms & Phenotypes for Angiomatosis

GenomeRNAi Phenotypes related to Angiomatosis according to GeneCards Suite gene sharing:

MGI Mouse Phenotypes related to Angiomatosis:

Drugs & Therapeutics for Angiomatosis

Drugs for Angiomatosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Genetic Tests for Angiomatosis

Anatomical Context for Angiomatosis

MalaCards organs/tissues related to Angiomatosis:

Publications for Angiomatosis

Articles related to Angiomatosis:

Genes for Angiomatosis

Genes related to Angiomatosis (0 elite genes):

Variations for Angiomatosis

Expression for Angiomatosis

Pathways for Angiomatosis

Pathways related to Angiomatosis according to GeneCards Suite gene sharing:

GO Terms for Angiomatosis

Biological processes related to Angiomatosis according to GeneCards Suite gene sharing:

Sources for Angiomatosis