MCID: ANG009
MIFTS: 32

Angiomatous Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Angiomatous Meningioma

MalaCards integrated aliases for Angiomatous Meningioma:

Name: Angiomatous Meningioma 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:6548
MeSH 41 D008579
NCIt 46 C4332
SNOMED-CT 64 73918009
UMLS 69 C0334608

Summaries for Angiomatous Meningioma

MalaCards based summary : Angiomatous Meningioma is related to meningioma, familial and pancreatic serous cystadenoma. An important gene associated with Angiomatous Meningioma is SEMA3A (Semaphorin 3A), and among its related pathways/superpathways are Development VEGF signaling via VEGFR2 - generic cascades and Proteoglycans in cancer. Related phenotypes are cardiovascular system and cellular

Related Diseases for Angiomatous Meningioma

Diseases related to Angiomatous Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 57)
# Related Disease Score Top Affiliating Genes
1 meningioma, familial 10.5
2 pancreatic serous cystadenoma 10.4 PGR VEGFA
3 preretinal fibrosis 10.4 GFAP VEGFA
4 angiokeratoma circumscriptum 10.3 KDR VEGFA
5 pediatric angiosarcoma 10.3 HBA1 VEGFA
6 clear cell meningioma 10.3 GFAP PGR
7 glomeruloid hemangioma 10.3 HBA1 VEGFA
8 chordoid glioma 10.3 GFAP PGR
9 acute hemorrhagic leukoencephalitis 10.2 KDR NRP1 VEGFA
10 breast angiosarcoma 10.2 HBA1 PGR
11 microcystic meningioma 10.2 GFAP VEGFA
12 exudative vitreoretinopathy 1 10.2 KDR NRP1 VEGFA
13 chronic myocardial ischemia 10.2 FGF2 VEGFA
14 cornea cancer 10.2 FGF2 GFAP
15 adenomyosis 10.2 PGR VEGFA
16 brachial plexus lesion 10.2 NRP1 SEMA3A WDFY2
17 epithelioid hemangioendothelioma 10.1 KDR VEGFA
18 angiodysplasia 10.1 FGF2 VEGFA
19 cell type cancer 10.1 HBA1 PGR VEGFA
20 juvenile nasopharyngeal angiofibroma 10.1 FGF2 PGR VEGFA
21 folic acid deficiency anemia 10.1 TF TFRC
22 skin hemangioma 10.1 HBA1 KDR VEGFA
23 capillary hemangioma 10.1 HBA1 KDR VEGFA
24 meninges hemangiopericytoma 10.1 GFAP HBA1 PLAUR
25 endometrial adenocarcinoma 10.1 FGF2 PGR VEGFA
26 papillary hidradenoma 10.1 GAPDH PGR WDFY2
27 vitreous disease 10.0 FGF2 GFAP VEGFA
28 retinal vascular disease 10.0 HBA1 KDR VEGFA
29 kuhnt-junius degeneration 10.0 KDR VEGFA
30 hemangiopericytoma, malignant 10.0
31 corneal neovascularization 10.0 FGF2 KDR VEGFA
32 limb ischemia 10.0 FGF2 KDR VEGFA
33 microvascular complications of diabetes 5 10.0 FGF2 KDR VEGFA
34 deep angioma 10.0 MEG8 PGR
35 hemangioma 10.0 FGF2 KDR VEGFA
36 brain cancer 10.0 GFAP PLAUR TFRC VEGFA
37 connective tissue cancer 10.0 FGF2 HBA1 VEGFA
38 astrocytoma 10.0 GFAP KDR VEGFA
39 lipodermatosclerosis 10.0 PLAUR VEGFA
40 intramuscular hemangioma 9.9 MEG8 PGR
41 pilocytic astrocytoma 9.9 FGF2 GFAP KDR
42 sturge-weber syndrome 9.9
43 hydrops, lactic acidosis, and sideroblastic anemia 9.9
44 hemangioblastoma 9.9
45 weber syndrome 9.9
46 aneurysm 9.9
47 hemoglobin h disease 9.8 HBA1 TF TFRC
48 microcytic anemia 9.8 HBA1 TF TFRC
49 senile angioma 9.8 HBA1 KDR TF
50 kidney cancer 9.8 FGF2 KDR VEGFA

Graphical network of the top 20 diseases related to Angiomatous Meningioma:



Diseases related to Angiomatous Meningioma

Symptoms & Phenotypes for Angiomatous Meningioma

MGI Mouse Phenotypes related to Angiomatous Meningioma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.96 PGR PLAUR SEMA3A TFRC FGF2 VEGFA
2 cellular MP:0005384 9.81 NRP1 PGR PLAUR SEMA3A TFRC FGF2
3 hematopoietic system MP:0005397 9.61 PGR PLAUR SEMA3A TF TFRC FGF2
4 muscle MP:0005369 9.17 PGR PLAUR FGF2 VEGFA GFAP KDR

Drugs & Therapeutics for Angiomatous Meningioma

Search Clinical Trials , NIH Clinical Center for Angiomatous Meningioma

Genetic Tests for Angiomatous Meningioma

Anatomical Context for Angiomatous Meningioma

Publications for Angiomatous Meningioma

Articles related to Angiomatous Meningioma:

(show all 16)
# Title Authors Year
1
Intradural angiomatous meningioma arising from a thoracic nerve root. ( 28868199 )
2017
2
Angiomatous meningioma have a very benign outcome despite frequent peritumoral edema at onset. ( 28844928 )
2017
3
Epidural angiomatous meningioma of the thoracic spine: A case report. ( 26870233 )
2016
4
Angiomatous meningioma in Sturge-Weber syndrome. ( 25766367 )
2015
5
Preoperative radiologic characters to predict hemangiopericytoma from angiomatous meningioma. ( 26298537 )
2015
6
Intraparenchymal Angiomatous Meningioma: A Diagnostic Dilemma. ( 26557529 )
2015
7
Elevated numbers of mast cells in angiomatous meningioma. ( 25207622 )
2014
8
Angiomatous meningioma of orbit mimicking as malignant neoplasm: a case report and literature review. ( 21780930 )
2011
9
Cystic angiomatous meningioma in the cerebellopontine angle mimicking hemangioblastoma. ( 21358102 )
2010
10
Angiomatous meningioma: a diagnostic dilemma. ( 18417856 )
2008
11
Angiomatous meningioma: a clinicopathologic study of 38 cases. ( 15104303 )
2004
12
Primary orbital angiomatous meningioma. ( 12523900 )
2003
13
A case of cystic form of angiomatous meningioma with prominent microvascular pattern mimicking haemangioblastoma. ( 11680633 )
2001
14
Biologic heterogeneity of angiomatous meningiomas. ( 10323082 )
1998
15
Fine structure of intracranial hemangiopericytoma and angiomatous meningioma. ( 4417339 )
1974
16
Suprasellar angiomatous meningioma simulating a large carotid aneurysm; report of case. ( 13413420 )
1957

Variations for Angiomatous Meningioma

Expression for Angiomatous Meningioma

Search GEO for disease gene expression data for Angiomatous Meningioma.

Pathways for Angiomatous Meningioma

Pathways related to Angiomatous Meningioma according to GeneCards Suite gene sharing:

(show all 16)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.17 KDR NRP1 PLAUR VEGFA
2 12.04 FGF2 KDR PLAUR VEGFA
3
Show member pathways
11.96 FGF2 KDR NRP1 VEGFA
4 11.85 FGF2 KDR VEGFA
5
Show member pathways
11.65 KDR NRP1 VEGFA
6 11.57 FGF2 GFAP VEGFA
7 11.45 TF TFRC VEGFA
8 11.23 FGF2 KDR VEGFA
9 11.18 FGF2 TF VEGFA
10 11.1 FGF2 KDR VEGFA
11 10.97 FGF2 VEGFA
12 10.96 FGF2 KDR VEGFA
13 10.92 GAPDH TF TFRC VEGFA
14
Show member pathways
10.74 KDR VEGFA
15 10.6 TF TFRC
16 10.51 FGF2 KDR VEGFA

GO Terms for Angiomatous Meningioma

Cellular components related to Angiomatous Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.95 FGF2 HBA1 NRP1 SEMA3A TF TFRC
2 cell surface GO:0009986 9.77 NRP1 PLAUR TF TFRC VEGFA
3 early endosome GO:0005769 9.35 KDR NRP1 TF TFRC WDFY2
4 neurofilament GO:0005883 9.32 GFAP NRP1
5 extracellular region GO:0005576 9.32 FGF2 HBA1 KDR MMP11 NRP1 PLAUR
6 HFE-transferrin receptor complex GO:1990712 9.26 TF TFRC
7 sorting endosome GO:0097443 9.16 KDR NRP1

Biological processes related to Angiomatous Meningioma according to GeneCards Suite gene sharing:

(show top 50) (show all 51)
# Name GO ID Score Top Affiliating Genes
1 angiogenesis GO:0001525 9.96 FGF2 KDR NRP1 VEGFA
2 extracellular matrix organization GO:0030198 9.94 FGF2 GFAP KDR MMP11
3 positive regulation of protein phosphorylation GO:0001934 9.84 KDR PLAUR VEGFA WDFY2
4 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.83 KDR NRP1 VEGFA
5 positive regulation of endothelial cell migration GO:0010595 9.76 KDR NRP1 VEGFA
6 semaphorin-plexin signaling pathway GO:0071526 9.71 NRP1 SEMA3A
7 artery morphogenesis GO:0048844 9.71 NRP1 VEGFA
8 motor neuron axon guidance GO:0008045 9.71 NRP1 SEMA3A
9 positive regulation of angiogenesis GO:0045766 9.71 FGF2 KDR NRP1 VEGFA
10 negative regulation of axon extension GO:0030517 9.7 NRP1 SEMA3A
11 axonal fasciculation GO:0007413 9.7 NRP1 SEMA3A
12 sympathetic nervous system development GO:0048485 9.7 NRP1 SEMA3A
13 positive chemotaxis GO:0050918 9.7 FGF2 NRP1 VEGFA
14 positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 9.69 NRP1 VEGFA
15 positive regulation of positive chemotaxis GO:0050927 9.69 KDR VEGFA
16 nerve development GO:0021675 9.69 NRP1 SEMA3A
17 facial nerve structural organization GO:0021612 9.68 NRP1 SEMA3A
18 coronary artery morphogenesis GO:0060982 9.68 NRP1 VEGFA
19 negative regulation of axon extension involved in axon guidance GO:0048843 9.68 NRP1 SEMA3A
20 sympathetic ganglion development GO:0061549 9.68 NRP1 SEMA3A
21 commissural neuron axon guidance GO:0071679 9.67 NRP1 VEGFA
22 endothelial cell chemotaxis GO:0035767 9.67 NRP1 VEGFA
23 axon extension involved in axon guidance GO:0048846 9.67 NRP1 SEMA3A
24 vascular endothelial growth factor signaling pathway GO:0038084 9.66 KDR NRP1
25 branchiomotor neuron axon guidance GO:0021785 9.65 NRP1 SEMA3A
26 positive regulation of axon extension involved in axon guidance GO:0048842 9.65 NRP1 VEGFA
27 regulation of axon extension involved in axon guidance GO:0048841 9.64 NRP1 SEMA3A
28 dichotomous subdivision of terminal units involved in salivary gland branching GO:0060666 9.63 NRP1 SEMA3A
29 trigeminal nerve structural organization GO:0021637 9.63 NRP1 SEMA3A
30 semaphorin-plexin signaling pathway involved in axon guidance GO:1902287 9.62 NRP1 SEMA3A
31 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway GO:0038033 9.62 KDR VEGFA
32 dendrite arborization GO:0140059 9.61 NRP1 SEMA3A
33 axonogenesis involved in innervation GO:0060385 9.61 NRP1 SEMA3A
34 positive regulation of blood vessel endothelial cell migration GO:0043536 9.61 FGF2 KDR VEGFA
35 neural crest cell migration involved in autonomic nervous system development GO:1901166 9.6 NRP1 SEMA3A
36 trigeminal ganglion development GO:0061551 9.59 NRP1 SEMA3A
37 sympathetic neuron projection extension GO:0097490 9.58 NRP1 SEMA3A
38 sympathetic neuron projection guidance GO:0097491 9.57 NRP1 SEMA3A
39 semaphorin-plexin signaling pathway involved in neuron projection guidance GO:1902285 9.56 NRP1 SEMA3A
40 ventral trunk neural crest cell migration GO:0036486 9.55 NRP1 SEMA3A
41 regulation of retinal ganglion cell axon guidance GO:0090259 9.51 NRP1 VEGFA
42 motor neuron migration GO:0097475 9.49 NRP1 VEGFA
43 facioacoustic ganglion development GO:1903375 9.48 NRP1 SEMA3A
44 gonadotrophin-releasing hormone neuronal migration to the hypothalamus GO:0021828 9.46 NRP1 SEMA3A
45 cellular response to vascular endothelial growth factor stimulus GO:0035924 9.43 KDR NRP1 VEGFA
46 VEGF-activated neuropilin signaling pathway GO:0038190 9.37 NRP1 VEGFA
47 positive regulation of focal adhesion assembly GO:0051894 9.33 KDR NRP1 VEGFA
48 positive regulation of retinal ganglion cell axon guidance GO:1902336 9.32 NRP1 VEGFA
49 positive regulation of endothelial cell proliferation GO:0001938 9.26 FGF2 KDR NRP1 VEGFA
50 cell migration involved in sprouting angiogenesis GO:0002042 8.92 FGF2 KDR NRP1 VEGFA

Molecular functions related to Angiomatous Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.43 GAPDH GFAP KDR PGR TFRC VEGFA
2 vascular endothelial growth factor-activated receptor activity GO:0005021 8.62 KDR NRP1

Sources for Angiomatous Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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