MCID: ANG009
MIFTS: 29

Angiomatous Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Angiomatous Meningioma

MalaCards integrated aliases for Angiomatous Meningioma:

Name: Angiomatous Meningioma 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:6548
MeSH 42 D008579
NCIt 47 C4332
SNOMED-CT 64 73918009
UMLS 69 C0334608

Summaries for Angiomatous Meningioma

MalaCards based summary : Angiomatous Meningioma is related to diffuse lipomatosis and hyperinsulinism. An important gene associated with Angiomatous Meningioma is SEMA3A (Semaphorin 3A), and among its related pathways/superpathways are Development VEGF signaling via VEGFR2 - generic cascades and Proteoglycans in cancer. Related phenotypes are cardiovascular system and cellular

Related Diseases for Angiomatous Meningioma

Diseases related to Angiomatous Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 52)
id Related Disease Score Top Affiliating Genes
1 diffuse lipomatosis 10.6 PGR VEGFA
2 hyperinsulinism 10.6 GFAP VEGFA
3 conventional angiosarcoma 10.5 HBA1 VEGFA
4 kidney pelvis papillary carcinoma 10.5 KDR VEGFA
5 pyoderma 10.5 GFAP PGR
6 salivary gland adenoid cystic carcinoma 10.4 HBA1 VEGFA
7 lens disease 10.4 KDR NRP1 VEGFA
8 thyroid angiosarcoma 10.3 HBA1 PGR
9 lipoic acid synthetase deficiency 10.3 PLAUR VEGFA
10 albinism, oculocutaneous, type ia 10.3 KDR NRP1 VEGFA
11 colorectal adenoma 10.3 FGF2 VEGFA
12 trachea carcinoma in situ 10.3 KDR PGR VEGFA
13 intestinal impaction 10.3 NRP1 SEMA3A WDFY2
14 iliac vein thrombophlebitis 10.2 KDR VEGFA
15 ulnar neuropathy 10.2 GFAP VEGFA
16 tooth erosion 10.2 FGF2 VEGFA
17 tetrahydrobiopterin-responsive hyperphenylalaninemia/phenylketonuria 10.2 FGF2 PGR VEGFA
18 cystitis 10.2 GFAP KDR PGR
19 extragonadal germ cell cancer 10.2 HBA1 KDR VEGFA
20 vesiculobullous skin disease 10.2 HBA1 KDR VEGFA
21 pericardial tuberculosis 10.2 GFAP HBA1 PLAUR
22 factitious disorder 10.2 HBA1 KDR VEGFA
23 spiradenoma 10.1 GAPDH PGR WDFY2
24 poems syndrome 10.1 TF TFRC
25 endometriosis of uterus 10.1 FGF2 PGR VEGFA
26 purulent endophthalmitis 10.1 FGF2 GFAP VEGFA
27 vernal conjunctivitis 10.1 HBA1 KDR VEGFA
28 coloboma of superior eyelid 10.1 KDR VEGFA
29 subdural empyema 10.1 FGF2 KDR VEGFA
30 renal fibrosis 10.1 FGF2 KDR VEGFA
31 timothy syndrome type 2 10.0 TF TFRC
32 citrullinemia, adult-onset type ii 10.0 FGF2 KDR VEGFA
33 nodular goiter 10.0 GFAP PLAUR TFRC VEGFA
34 fuhrmann syndrome 10.0 FGF2 KDR VEGFA
35 gestational choriocarcinoma 10.0 FGF2 HBA1 VEGFA
36 endophthalmitis 10.0 MEG8 PGR
37 hematopoietic stem cell transplantation 10.0 FGF2 KDR VEGFA
38 adenosine monophosphate deaminase 1 deficiency 10.0 PGR VEGFA
39 distal arthrogryposis 10.0 HBA1 TF
40 cutaneous mucoepidermoid carcinoma 9.9 MEG8 PGR
41 diencephalic astrocytomas 9.9 FGF2 GFAP KDR
42 cat-scratch disease 9.8 HBA1 TF TFRC
43 alcohol-induced mental disorder 9.8 HBA1 KDR TF
44 hemangioblastoma 9.8
45 weber syndrome 9.8
46 aneurysm 9.8
47 tongue squamous cell carcinoma 9.7 HBA1 TF TFRC
48 mantle cell lymphoma 9.7 FGF2 GFAP KDR VEGFA
49 mitral valve stenosis 9.6 FGF2 HBA1 KDR VEGFA
50 malaria 9.5 GAPDH HBA1 PLAUR TFRC VEGFA

Graphical network of the top 20 diseases related to Angiomatous Meningioma:



Diseases related to Angiomatous Meningioma

Symptoms & Phenotypes for Angiomatous Meningioma

MGI Mouse Phenotypes related to Angiomatous Meningioma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.96 FGF2 GFAP KDR MMP11 NRP1 PGR
2 cellular MP:0005384 9.81 FGF2 GFAP KDR NRP1 PGR PLAUR
3 hematopoietic system MP:0005397 9.61 FGF2 KDR NRP1 PGR PLAUR SEMA3A
4 muscle MP:0005369 9.17 FGF2 GFAP KDR NRP1 PGR PLAUR

Drugs & Therapeutics for Angiomatous Meningioma

Search Clinical Trials , NIH Clinical Center for Angiomatous Meningioma

Genetic Tests for Angiomatous Meningioma

Anatomical Context for Angiomatous Meningioma

Publications for Angiomatous Meningioma

Articles related to Angiomatous Meningioma:

(show all 16)
id Title Authors Year
1
Intradural angiomatous meningioma arising from a thoracic nerve root. ( 28868199 )
2017
2
Angiomatous meningioma have a very benign outcome despite frequent peritumoral edema at onset. ( 28844928 )
2017
3
Epidural angiomatous meningioma of the thoracic spine: A case report. ( 26870233 )
2016
4
Intraparenchymal Angiomatous Meningioma: A Diagnostic Dilemma. ( 26557529 )
2015
5
Preoperative radiologic characters to predict hemangiopericytoma from angiomatous meningioma. ( 26298537 )
2015
6
Angiomatous meningioma in Sturge-Weber syndrome. ( 25766367 )
2015
7
Elevated numbers of mast cells in angiomatous meningioma. ( 25207622 )
2014
8
Angiomatous meningioma of orbit mimicking as malignant neoplasm: a case report and literature review. ( 21780930 )
2011
9
Cystic angiomatous meningioma in the cerebellopontine angle mimicking hemangioblastoma. ( 21358102 )
2010
10
Angiomatous meningioma: a diagnostic dilemma. ( 18417856 )
2008
11
Angiomatous meningioma: a clinicopathologic study of 38 cases. ( 15104303 )
2004
12
Primary orbital angiomatous meningioma. ( 12523900 )
2003
13
A case of cystic form of angiomatous meningioma with prominent microvascular pattern mimicking haemangioblastoma. ( 11680633 )
2001
14
Biologic heterogeneity of angiomatous meningiomas. ( 10323082 )
1998
15
Fine structure of intracranial hemangiopericytoma and angiomatous meningioma. ( 4417339 )
1974
16
Suprasellar angiomatous meningioma simulating a large carotid aneurysm; report of case. ( 13413420 )
1957

Variations for Angiomatous Meningioma

Expression for Angiomatous Meningioma

Search GEO for disease gene expression data for Angiomatous Meningioma.

Pathways for Angiomatous Meningioma

GO Terms for Angiomatous Meningioma

Cellular components related to Angiomatous Meningioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.95 FGF2 HBA1 NRP1 SEMA3A TF TFRC
2 cell surface GO:0009986 9.77 NRP1 PLAUR TF TFRC VEGFA
3 early endosome GO:0005769 9.56 KDR NRP1 TF WDFY2
4 extracellular region GO:0005576 9.32 FGF2 HBA1 KDR MMP11 NRP1 PLAUR
5 HFE-transferrin receptor complex GO:1990712 9.16 TF TFRC
6 neurofilament GO:0005883 9.02 NRP1
7 sorting endosome GO:0097443 8.96 KDR NRP1

Biological processes related to Angiomatous Meningioma according to GeneCards Suite gene sharing:

(show all 50)
id Name GO ID Score Top Affiliating Genes
1 angiogenesis GO:0001525 9.95 FGF2 KDR NRP1 VEGFA
2 positive regulation of angiogenesis GO:0045766 9.87 FGF2 KDR VEGFA
3 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.83 KDR NRP1 VEGFA
4 positive regulation of protein phosphorylation GO:0001934 9.81 KDR PLAUR VEGFA WDFY2
5 extracellular matrix organization GO:0030198 9.8 FGF2 KDR MMP11
6 positive regulation of endothelial cell migration GO:0010595 9.74 KDR NRP1 VEGFA
7 semaphorin-plexin signaling pathway GO:0071526 9.71 NRP1 SEMA3A
8 artery morphogenesis GO:0048844 9.71 NRP1 VEGFA
9 positive regulation of blood vessel endothelial cell migration GO:0043536 9.7 FGF2 VEGFA
10 motor neuron axon guidance GO:0008045 9.7 NRP1 SEMA3A
11 negative regulation of axon extension GO:0030517 9.7 NRP1 SEMA3A
12 axonal fasciculation GO:0007413 9.69 NRP1 SEMA3A
13 sympathetic nervous system development GO:0048485 9.69 NRP1 SEMA3A
14 positive regulation of positive chemotaxis GO:0050927 9.68 KDR VEGFA
15 nerve development GO:0021675 9.68 NRP1 SEMA3A
16 facial nerve structural organization GO:0021612 9.68 NRP1 SEMA3A
17 endothelial cell chemotaxis GO:0035767 9.67 NRP1 VEGFA
18 coronary artery morphogenesis GO:0060982 9.67 NRP1 VEGFA
19 negative regulation of axon extension involved in axon guidance GO:0048843 9.67 NRP1 SEMA3A
20 positive chemotaxis GO:0050918 9.67 FGF2 NRP1 VEGFA
21 sympathetic ganglion development GO:0061549 9.66 NRP1 SEMA3A
22 commissural neuron axon guidance GO:0071679 9.65 NRP1 VEGFA
23 axon extension involved in axon guidance GO:0048846 9.65 NRP1 SEMA3A
24 branchiomotor neuron axon guidance GO:0021785 9.64 NRP1 SEMA3A
25 vascular endothelial growth factor signaling pathway GO:0038084 9.64 KDR NRP1
26 positive regulation of axon extension involved in axon guidance GO:0048842 9.63 NRP1 VEGFA
27 regulation of axon extension involved in axon guidance GO:0048841 9.62 NRP1 SEMA3A
28 dichotomous subdivision of terminal units involved in salivary gland branching GO:0060666 9.62 NRP1 SEMA3A
29 semaphorin-plexin signaling pathway involved in axon guidance GO:1902287 9.61 NRP1 SEMA3A
30 trigeminal nerve structural organization GO:0021637 9.61 NRP1 SEMA3A
31 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway GO:0038033 9.6 KDR VEGFA
32 axonogenesis involved in innervation GO:0060385 9.59 NRP1 SEMA3A
33 trigeminal ganglion development GO:0061551 9.58 NRP1 SEMA3A
34 neural crest cell migration involved in autonomic nervous system development GO:1901166 9.58 NRP1 SEMA3A
35 ventral trunk neural crest cell migration GO:0036486 9.56 NRP1 SEMA3A
36 sympathetic neuron projection extension GO:0097490 9.55 NRP1 SEMA3A
37 sympathetic neuron projection guidance GO:0097491 9.54 NRP1 SEMA3A
38 semaphorin-plexin signaling pathway involved in neuron projection guidance GO:1902285 9.52 NRP1 SEMA3A
39 regulation of retinal ganglion cell axon guidance GO:0090259 9.48 NRP1 VEGFA
40 motor neuron migration GO:0097475 9.46 NRP1 VEGFA
41 facioacoustic ganglion development GO:1903375 9.43 NRP1 SEMA3A
42 gonadotrophin-releasing hormone neuronal migration to the hypothalamus GO:0021828 9.4 NRP1 SEMA3A
43 positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 9.38 VEGFA
44 positive regulation of retinal ganglion cell axon guidance GO:1902336 9.37 NRP1 VEGFA
45 cellular response to vascular endothelial growth factor stimulus GO:0035924 9.33 KDR NRP1 VEGFA
46 VEGF-activated neuropilin signaling pathway GO:0038190 9.32 NRP1 VEGFA
47 positive regulation of focal adhesion assembly GO:0051894 9.26 KDR VEGFA
48 positive regulation of endothelial cell proliferation GO:0001938 9.26 FGF2 KDR NRP1 VEGFA
49 cell migration involved in sprouting angiogenesis GO:0002042 8.92 FGF2 KDR NRP1 VEGFA
50 multicellular organism development GO:0007275 10.16 FGF2 KDR MMP11 NRP1 SEMA3A VEGFA

Molecular functions related to Angiomatous Meningioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 vascular endothelial growth factor-activated receptor activity GO:0005021 8.62 KDR NRP1

Sources for Angiomatous Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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