MCID: ANG002
MIFTS: 40

Angiostrongyliasis malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Angiostrongyliasis

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Sources:
11Disease Ontology, 46NIH Rare Diseases, 13DISEASES, 52Orphanet, 66UMLS, 29ICD10 via Orphanet, 38MESH via Orphanet, 67UMLS via Orphanet, 28ICD10
See all MalaCards sources

Aliases & Descriptions for Angiostrongyliasis:

Name: Angiostrongyliasis 11 46 13 52 66

Classifications:



External Ids:

Disease Ontology11 DOID:0050256
Orphanet52 ORPHA74
ICD10 via Orphanet29 B81.3, B83.2
MESH via Orphanet38 C536369
UMLS via Orphanet67 C0392662
ICD1028 B83.2

Summaries for Angiostrongyliasis

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Disease Ontology:11 A parasitic helminthiasis infectious disease that involves parasitic infection of the intestine, central nervous system and eyes by angiostrongylus cantonensis or angiostrongylus costaricensis.

MalaCards based summary: Angiostrongyliasis is related to peritonitis and meningitis. An important gene associated with Angiostrongyliasis is MMP9 (Matrix Metallopeptidase 9), and among its related pathways are Validated transcriptional targets of AP1 family members Fra1 and Fra2 and Osteopontin-mediated events. Affiliated tissues include eye, kidney and testes, and related mouse phenotypes are neoplasm and reproductive system.

Wikipedia:69 Angiostrongyliasis is an infection by a nematode from the Angiostrongylus genus of kidney and alimentary... more...

Related Diseases for Angiostrongyliasis

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Diseases related to Angiostrongyliasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 134)
idRelated DiseaseScoreTop Affiliating Genes
1peritonitis10.5MMP9, PLAU
2meningitis10.4
3eosinophilic meningitis10.4
4cytoplasmic body myopathy10.3IL13, IL5
5giant ganglionic hyperplasia10.3CCL11, IL5
6aortic arch interruption10.3IL13, IL5
7toxic diffuse goiter10.3IL13, IL5
8fungal gastritis10.3CCL11, IL5
9cherry allergy10.3IL13, IL5
10benign mammary dysplasia10.3CCL11, IL5
11skin disease10.3IL13, IL5
12mechanical ectropion10.3IL4, MMP9
13urinary bladder small cell neuroendocrine carcinoma10.3IL13, IL5
14polyradiculoneuropathy10.3IL13, IL5
15retroperitoneal cancer10.3CCL11, IL5
16autoimmune neuropathy10.3IL13, IL5
17pediatric germ cell cancer10.3IL13, IL5
18keratoconjunctivitis10.2IL4, IL5
19chronic pulmonary heart disease10.2IL4, IL5
20myositis fibrosa10.2IL4, IL5
21progressive relapsing multiple sclerosis10.2IL4, MMP9
22acute conjunctivitis10.2IL4, IL5
23african histoplasmosis10.2IL4, IL5
24spermatic cord cancer10.2IL4, IL5
25multiple system atrophy, cerebellar type10.2IL4, IL5
26peanut allergy10.2IL4, IL5
27nervous system cancer10.2IL4, MMP9
28philophthalmiasis10.2IL4, IL5
29papillary conjunctivitis10.2CCL11, IL4
30anterior dislocation of lens10.2CCL11, IL4
31retinal vascular disease10.2CCL11, IL4
32goat milk allergy10.2IL13, IL4
33gonococcal keratitis10.2IL4, IL5
34cow milk allergy10.2IL13, IL4
35abdominal tuberculosis10.1IL13, IL4
36wissler's syndrome10.1IL4, IL5
37juvenile dermatitis herpetiformis10.1CCL11, IL4
38optic neuritis10.1
39neuritis10.1
40lung sarcoma10.0IL4, IL5
41jejunal somatostatinoma10.0IL2, MMP9
42subcorneal pustular dermatosis10.0IL4, IL5
43meningoencephalitis10.0
44appendicitis10.0
45vaginal squamous tumor10.0IL2, IL5
46deafness, autosomal recessive 6210.0IL4, IL5
47blepharochalasis10.0MMP9, PLAU
48radioulnar synostosis retinal pigment abnormalities10.0IL2, IL5
49gastric ulcer9.9IL2, IL5
50gonococcal synovitis9.9IL4, IL5, MMP9

Graphical network of the top 20 diseases related to Angiostrongyliasis:



Diseases related to angiostrongyliasis

Symptoms for Angiostrongyliasis

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Drugs & Therapeutics for Angiostrongyliasis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Angiostrongyliasis

Genetic Tests for Angiostrongyliasis

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Anatomical Context for Angiostrongyliasis

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MalaCards organs/tissues related to Angiostrongyliasis:

34
Eye, Kidney, Testes, Skin, Liver, Colon, Lung

Animal Models for Angiostrongyliasis or affiliated genes

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MGI Mouse Phenotypes related to Angiostrongyliasis:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.7IL2, IL5, MMP9, PLAU
2MP:00053897.3IL13, IL2, IL4, IL5, MMP9, PLAU
3MP:00053787.2IL13, IL2, IL4, IL5, MMP9, PLAU
4MP:00053877.0CCL11, IL13, IL2, IL4, IL5, MMP9
5MP:00053886.9CCL11, IL13, IL2, IL4, IL5, MMP9
6MP:00053816.9IL13, IL2, IL4, IL5, MMP9, PLAU
7MP:00053976.7CCL11, IL13, IL2, IL4, IL5, MMP9

Publications for Angiostrongyliasis

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Articles related to Angiostrongyliasis:

(show top 50)    (show all 138)
idTitleAuthorsYear
1
Cloning and expression of a 16-kDa recombinant protein from Angiostrongylus cantonensis for use in immunoblot diagnosis of human angiostrongyliasis. (27406573)
2016
2
Abdominal angiostrongyliasis mimicking acute appendicitis. (25928828)
2015
3
Anterior chamber angiostrongyliasis. (23846206)
2013
4
Endemic angiostrongyliasis in the Brazilian Amazon: natural parasitism of Angiostrongylus cantonensis in Rattus rattus and R. norvegicus, and sympatric giant African land snails, Achatina fulica. (23072946)
2013
5
Workshop on research priorities for management and treatment of angiostrongyliasis(1). (23171634)
2012
6
Lung CT findings of angiostrongyliasis cantonensis caused by Angiostrongylus cantonensis. (21513853)
2011
7
An outbreak of angiostrongyliasis in Guanging, People's Republic of China: migrants vulnerable to an emerging disease. (22299428)
2011
8
Human ocular angiostrongyliasis: a literature review. (21296846)
2011
9
Comparison of major immunoglobulins intrathecal synthesis patterns in Ecuadorian and Cuban patients with angiostrongyliasis. (21363978)
2011
10
Development of a double antibody sandwich ELISA assay for the diagnosis of angiostrongyliasis. (21506824)
2011
11
Abdominal angiostrongyliasis caused by Angiostrongylus cantonensis: a possible cause of eosinophilic infiltration in human digestive tract. (19545957)
2010
12
Cerebrospinal fluid u-plasminogen activator and matrix metalloproteinase-9 levels in human eosinophilic meningitis associated with angiostrongyliasis. (20584616)
2010
13
Use of heterologous antigens for the immunodiagnosis of abdominal angiostrongyliasis by an enzyme-linked immunosorbent assay. (21120363)
2010
14
Immunological diagnosis of human angiostrongyliasis due to Angiostrongylus cantonensis (Nematoda: Angiostrongylidae). (19117782)
2009
15
Abdominal angiostrongyliasis: what does the rheumatologist must know about it? (20374358)
2009
16
Cerebrospinal fluid cytokine responses in human eosinophilic meningitis associated with angiostrongyliasis. (17928005)
2008
17
Enzootic angiostrongyliasis in Shenzhen, China. (19046534)
2008
18
Ocular angiostrongyliasis in a child--first case report from India. (16186138)
2006
19
Ocular Angiostrongyliasis: removal of a live nematode from the anterior chamber. (15232595)
2005
20
Ocular parastrongyliasis (=angiostrongyliasis): probable first report of human infection from a patient in Ceylon (Sri Lanka). (15828436)
2004
21
Diagnosis of abdominal angiostrongyliasis by PCR from sera of patients. (14743672)
2003
22
First report of human angiostrongyliasis acquired in Sydney. (14558868)
2003
23
Evaluation of human IgG subclass antibodies in the serodiagnosis of angiostrongyliasis. (12658452)
2003
24
Drug trials for treatment of human angiostrongyliasis. (14502343)
2003
25
Ocular angiostrongyliasis without meningitis symptoms in Okinawa, Japan. (12053973)
2002
26
A clinical study of eosinophilic meningoencephalitis caused by angiostrongyliasis. (12411101)
2002
27
Specific IgG antibody subclasses to Angiostrongylus cantonensis in patients with angiostrongyliasis. (12744624)
2002
28
Third report of ocular parastrongyliasis (angiostrongyliasis) from Sri Lanka. (11921545)
2001
29
Angiostrongyliasis: analysis of antigens of Angiostrongylus costaricensis adult worms versus IgG from infected patients with Angiostrongylus cantonensis. (11414459)
2000
30
Jejunal perforation caused by abdominal angiostrongyliasis. (10602548)
1999
31
First reported outbreak of abdominal angiostrongyliasis. (9580096)
1998
32
Cerebrospinal angiostrongyliasis in five captive tamarins (Sanguinus spp). (9578750)
1998
33
Clinical and epidemiological aspects of abdominal angiostrongyliasis in southern Brazil. (1844964)
1991
34
Histopathological criteria for the diagnosis of abdominal angiostrongyliasis. (1792232)
1991
35
The first human case of angiostrongyliasis cantonensis in the mainland of China. (3150716)
1988
36
Abdominal angiostrongyliasis--an under-diagnosed disease. (3509192)
1987
37
First report of human angiostrongyliasis in Hong Kong diagnosed by computerized axial topography (CAT) and enzyme linked immunosorbent assay. (6464132)
1984
38
Studies on suspected clinical and experimental angiostrongyliasis: serological responses. (6443362)
1984
39
A case of abdominal angiostrongyliasis in a monkey. (6632451)
1983
40
Angiostrongyliasis in Port Moresby, Papua New Guinea. (6586158)
1983
41
Eosinophilic radiculomyeloencephalitis: an angiostrongyliasis outbreak in American Samoa related to ingestion of Achatina fulica snails. (7149098)
1982
42
Three cases of worm proven human angiostrongyliasis in Taiwan. (7343202)
1981
43
Angiostrongyliasis in Australia. (6930222)
1980
44
Clinical observations and immunodiagnosis of angiostrongyliasis in North Taiwan. (7219318)
1980
45
Angiostrongyliasis cantonensis. (287448)
1979
46
Pathological findings in four cases of human angiostrongyliasis. (725653)
1978
47
Angiostrongyliasis in Indonesia: additional geographic and host occurrence records. (751218)
1978
48
Case of ocular angiostrongyliasis associated with eosinophilic meningitis. (5102754)
1971
49
Eosinophilic meningoencephalitis caused by angiostrongyliasis in Thailand. Autopsy report. (4952148)
1967
50
Second case of ocular angiostrongyliasis in Thailand. (5901630)
1966

Variations for Angiostrongyliasis

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Expression for genes affiliated with Angiostrongyliasis

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Search GEO for disease gene expression data for Angiostrongyliasis.

Pathways for genes affiliated with Angiostrongyliasis

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Pathways related to Angiostrongyliasis according to GeneCards Suite gene sharing:

(show all 32)
idSuper pathwaysScoreTop Affiliating Genes
19.6MMP9, PLAU
29.6MMP9, PLAU
39.6MMP9, PLAU
49.6MMP9, PLAU
59.6MMP9, PLAU
69.6MMP9, PLAU
79.6MMP9, PLAU
89.3IL13, IL2
9
Show member pathways
8.8IL13, IL2, IL5
10
Show member pathways
8.8IL13, IL2, IL5
118.8IL2, IL4, MMP9
128.7CCL11, IL4, IL5
13
Show member pathways
8.6IL2, IL4, IL5
148.6IL2, IL4, IL5
15
Show member pathways
8.6IL2, IL4, IL5
168.6IL2, IL4, IL5
178.5IL13, IL4, IL5
18
Show member pathways
8.5IL13, IL4, IL5
198.0IL13, IL2, IL4, IL5
208.0IL13, IL2, IL4, IL5
218.0IL13, IL2, IL4, IL5
228.0IL13, IL2, IL4, IL5
23
Show member pathways
8.0IL13, IL2, IL4, IL5
24
Show member pathways
8.0IL13, IL2, IL4, IL5
25
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5
267.6CCL11, IL13, IL2, IL4, IL5
277.6CCL11, IL13, IL2, IL4, IL5
28
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5
29
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5
30
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5
31
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5
32
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5

GO Terms for genes affiliated with Angiostrongyliasis

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Cellular components related to Angiostrongyliasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055767.3CCL11, IL13, IL2, IL5, MMP9, PLAU
2extracellular spaceGO:00056156.7CCL11, IL13, IL2, IL4, IL5, MMP9

Biological processes related to Angiostrongyliasis according to GeneCards Suite gene sharing:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of immunoglobulin secretionGO:005102410.1IL2, IL5
2embryo implantationGO:000756610.0MMP9, PLAU
3negative regulation of complement-dependent cytotoxicityGO:19036609.7IL13, IL4
4positive regulation of activated T cell proliferationGO:00421049.7IL2, IL4
5positive regulation of isotype switching to IgG isotypesGO:00483049.7IL2, IL4
6positive regulation of T cell differentiationGO:00455829.7IL2, IL4
7regulation of proton transportGO:00101559.7IL13, IL4
8positive regulation of mast cell degranulationGO:00433069.7IL13, IL4
9negative regulation of endothelial cell apoptotic processGO:20003529.7IL13, IL4
10positive regulation of tyrosine phosphorylation of Stat5 proteinGO:00425239.6IL2, IL4
11positive regulation of immunoglobulin productionGO:00026399.6IL13, IL4
12microglial cell activationGO:00017749.6IL13, IL4
13extrinsic apoptotic signaling pathway in absence of ligandGO:00971929.6IL2, IL4
14inflammatory responseGO:00069549.2CCL11, IL13, IL5
15positive regulation of protein phosphorylationGO:00019349.2IL2, IL4, MMP9
16chemotaxisGO:00069359.0CCL11, IL4, PLAU
17positive regulation of B cell proliferationGO:00308908.6IL13, IL2, IL4, IL5
18response to ethanolGO:00454718.5IL13, IL2, IL4
19immune responseGO:00069558.0IL13, IL2, IL4, IL5
20positive regulation of cell proliferationGO:00082847.9IL2, IL4, IL5, PLAU

Molecular functions related to Angiostrongyliasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1growth factor activityGO:00080838.6IL2, IL4, IL5
2cytokine activityGO:00051257.7IL13, IL2, IL4, IL5

Sources for Angiostrongyliasis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet