MCID: ANG002
MIFTS: 39

Angiostrongyliasis malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Angiostrongyliasis

About this section
Sources:
11Disease Ontology, 13DISEASES, 30ICD10, 31ICD10 via Orphanet, 40MESH via Orphanet, 48NIH Rare Diseases, 54Orphanet, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Angiostrongyliasis:

Name: Angiostrongyliasis 11 48 54 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:0050256
Orphanet54 ORPHA74
ICD10 via Orphanet31 B81.3, B83.2
MESH via Orphanet40 C536369
UMLS via Orphanet69 C0392662
ICD1030 B83.2

Summaries for Angiostrongyliasis

About this section
Disease Ontology:11 A parasitic helminthiasis infectious disease that involves parasitic infection of the intestine, central nervous system and eyes by Angiostrongylus cantonensis or Angiostrongylus costaricensis.

MalaCards based summary: Angiostrongyliasis is related to meningitis and eosinophilic meningitis. An important gene associated with Angiostrongyliasis is MMP9 (Matrix Metallopeptidase 9), and among its related pathways are FGF signaling pathway and Validated transcriptional targets of AP1 family members Fra1 and Fra2. Affiliated tissues include eye, kidney and testes, and related mouse phenotypes are neoplasm and digestive/alimentary.

Wikipedia:71 Angiostrongyliasis is an infection by a nematode from the Angiostrongylus genus of kidney and alimentary... more...

Related Diseases for Angiostrongyliasis

About this section

Diseases related to Angiostrongyliasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 126)
idRelated DiseaseScoreTop Affiliating Genes
1meningitis10.3
2eosinophilic meningitis10.2
3nonossifying fibromyxoid tumor10.2MMP9, PLAU
4retinal artery occlusion10.2CCL11, MMP9
5peptidic growth factors deficiency10.1CCL11, IL5
6latent syphilis10.1CCL11, IL5
7necrotizing gastritis10.1CCL11, IL5
8dahlberg borer newcomer syndrome10.1IL13, IL5
9aortic atherosclerosis10.1IL13, IL5
10renal hypertension10.1IL13, IL5
11hypercementosis10.1IL13, IL5
12exudative vitreoretinopathy 2, x-linked10.1IL13, IL5
13stickler syndrome, type v10.1IL2, MMP9
14smooth muscle tumor10.1IL13, IL5
15ectropion10.1IL4, MMP9
16prostate small cell carcinoma10.1IL13, IL5
17psychotic disorder10.0CCL11, IL4
18anterior dislocation of lens10.0CCL11, IL4
19retinal vascular disease10.0CCL11, IL4
20metal allergy10.0IL13, IL5
21inclusion conjunctivitis10.0IL2, IL5
22sarcoma10.0IL2, IL4
23vulvar vestibulitis syndrome10.0IL2, IL4
24autosomal dominant deafness-onychodystrophy syndrome10.0IL2, IL4
25ovarian mucinous neoplasm10.0IL13, IL5
26crustacean allergy10.0IL13, IL4
27goat milk allergy10.0IL13, IL4
28wilkes stevenson syndrome10.0IL2, IL5
29clostridium difficile colitis10.0IL2, IL4
30gonadal disease10.0IL2, IL4
31marasmus10.0IL4, IL5
32opitz-kaveggia syndrome10.0IL2, IL4
33papillary squamous carcinoma10.0IL4, IL5
34lens-induced iridocyclitis10.0IL4, IL5
35hypersensitivity vasculitis10.0IL4, IL5
36tularemia10.0IL2, IL4
37optic neuritis10.0
38neuritis10.0
39spastic diplegia10.0CCL11, IL13, IL5
40allescheriosis10.0IL4, IL5
41disordered steroidogenesis due to cytochrome p450 oxidoreductase9.9CCL11, IL13, IL5
42central nervous system origin vertigo9.9IL2, IL4
43breast intracanalicular fibroadenoma9.9IL4, IL5
44childhood malignant mesenchymoma9.9CCL11, IL13, IL5
45histoplasmosis retinitis9.9IL4, IL5
46conjunctival concretion9.9CCL11, IL13, IL5
47birth defects9.9CCL11, IL13, IL5
48acute myeloid leukemia with recurrent genetic anomaly9.9IL2, IL4
49rectum squamous cell carcinoma9.9CCL11, IL13, IL5
50isolated klippel-feil syndrome9.9IL4, IL5

Graphical network of the top 20 diseases related to Angiostrongyliasis:



Diseases related to angiostrongyliasis

Symptoms & Phenotypes for Angiostrongyliasis

About this section

MGI Mouse Phenotypes related to Angiostrongyliasis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020069.3IL2, IL5, MMP9, PLAU
2MP:00053818.0IL13, IL2, IL4, IL5, MMP9, PLAU
3MP:00053788.0IL13, IL2, IL4, IL5, MMP9, PLAU
4MP:00053897.9IL13, IL2, IL4, IL5, MMP9, PLAU
5MP:00053977.6CCL11, IL13, IL2, IL4, IL5, MMP9
6MP:00053877.5CCL11, IL13, IL2, IL4, IL5, MMP9
7MP:00053886.7CCL11, IL13, IL2, IL4, IL5, MMP9

Drugs & Therapeutics for Angiostrongyliasis

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Angiostrongyliasis

Genetic Tests for Angiostrongyliasis

About this section

Anatomical Context for Angiostrongyliasis

About this section

MalaCards organs/tissues related to Angiostrongyliasis:

36
Eye, Kidney, Testes, Skin, Liver, Colon, Lung

Publications for Angiostrongyliasis

About this section

Articles related to Angiostrongyliasis:

(show top 50)    (show all 139)
idTitleAuthorsYear
1
First Evidence of Angiostrongyliasis Caused by Angiostrongylus cantonensis in Guadeloupe, Lesser Antilles. (28070007)
2017
2
Cloning and expression of a 16-kDa recombinant protein from Angiostrongylus cantonensis for use in immunoblot diagnosis of human angiostrongyliasis. (27406573)
2016
3
A Case of Ocular Angiostrongyliasis with Molecular Identification of the Species in Vietnam. (26797438)
2015
4
Abdominal angiostrongyliasis mimicking acute appendicitis. (25928828)
2015
5
Emergence of neural angiostrongyliasis in eastern australia. (25793473)
2015
6
Follow-up on anterior chamber angiostrongyliasis. (25124954)
2014
7
PCR for the diagnosis of abdominal angiostrongyliasis in formalin-fixed paraffin-embedded human tissue. (24705328)
2014
8
Acute eosinophilic meningitis and orbital inflammation from presumed angiostrongyliasis. (24862785)
2014
9
Intrathecal activation as a typical immune response within the central nervous system in angiostrongyliasis. (23390222)
2013
10
Angiostrongyliasis in Thailand: epidemiology and laboratory investigations. (23901379)
2013
11
The role of eosinophils in angiostrongyliasis: multiple roles for a versatile cell? (23901384)
2013
12
Comprehensive review of ocular angiostrongyliasis with special reference to optic neuritis. (24516263)
2013
13
Anterior chamber angiostrongyliasis. (23846206)
2013
14
Differential diagnosis of CNS angiostrongyliasis: a short review. (23901385)
2013
15
Pathways for transmission of angiostrongyliasis and the risk of disease associated with them. (23901388)
2013
16
Endemic angiostrongyliasis in the Brazilian Amazon: natural parasitism of Angiostrongylus cantonensis in Rattus rattus and R. norvegicus, and sympatric giant African land snails, Achatina fulica. (23072946)
2013
17
Neuroimaging features in neuro-gnathostomiasis and angiostrongyliasis. (22271262)
2013
18
Subretinal angiostrongyliasis-induced optic neuritis. (23818750)
2013
19
A comparative study of neuroimaging features between human neuro-gnathostomiasis and angiostrongyliasis. (22124854)
2012
20
How can clinicians ensure the diagnosis of meningitic angiostrongyliasis? (21923259)
2012
21
Enzootic angiostrongyliasis in Guangzhou, China, 2008-2010. (22556086)
2012
22
Workshop on research priorities for management and treatment of angiostrongyliasis(1). (23171634)
2012
23
Endemic angiostrongyliasis, Rio de Janeiro, Brazil. (21762612)
2011
24
Comparison of major immunoglobulins intrathecal synthesis patterns in Ecuadorian and Cuban patients with angiostrongyliasis. (21363978)
2011
25
Lung CT findings of angiostrongyliasis cantonensis caused by Angiostrongylus cantonensis. (21513853)
2011
26
Abdominal angiostrongyliasis with involvement of liver histopathologically confirmed: a case report. (21915466)
2011
27
An outbreak of angiostrongyliasis in Guanging, People's Republic of China: migrants vulnerable to an emerging disease. (22299428)
2011
28
International symposium on Angiostrongylus and Angiostrongyliasis, 2010. (21762566)
2011
29
Treatment of angiostrongyliasis using a combination of albendazole and dexamethasone: the results of a retrospective and comparative study. (21294950)
2011
30
Enzootic angiostrongyliasis, Guangdong, China, 2008-2009. (21762614)
2011
31
Human ocular angiostrongyliasis: a literature review. (21296846)
2011
32
Development of a double antibody sandwich ELISA assay for the diagnosis of angiostrongyliasis. (21506824)
2011
33
An indirect immunofluorescence antibody test employing whole eggs as the antigen for the diagnosis of abdominal angiostrongyliasis. (21739024)
2011
34
Outcomes in mice with abdominal angiostrongyliasis treated with enoxaparin. (21400113)
2011
35
Peripheral eosinophilia as an indicator of meningitic angiostrongyliasis in exposed individuals. (21120370)
2010
36
Application of recombinant SMR-domain containing protein of angiostrongylus cantonensis in immunoblot diagnosis of human angiostrongyliasis. (21073053)
2010
37
Abdominal angiostrongyliasis caused by Angiostrongylus cantonensis: a possible cause of eosinophilic infiltration in human digestive tract. (19545957)
2010
38
Identification of factors associated with clinically severe angiostrongyliasis. (21118948)
2010
39
Cerebrospinal fluid u-plasminogen activator and matrix metalloproteinase-9 levels in human eosinophilic meningitis associated with angiostrongyliasis. (20584616)
2010
40
Use of heterologous antigens for the immunodiagnosis of abdominal angiostrongyliasis by an enzyme-linked immunosorbent assay. (21120363)
2010
41
Human angiostrongyliasis outbreak in Dali, China. (19771154)
2009
42
Colon mass secondary to angiostrongyliasis. (19345351)
2009
43
Ocular angiostrongyliasis--first case report from Jamaica. (20099782)
2009
44
Angiostrongyliasis in the Americas. (19523320)
2009
45
Abdominal angiostrongyliasis: what does the rheumatologist must know about it? (20374358)
2009
46
Thai koi-hoi snail dish and angiostrongyliasis due to Angiostrongylus cantonensis: Effects of food flavoring and alcoholic drink on the third-stage larvae in infected snail meat. (19272010)
2009
47
Immunological diagnosis of human angiostrongyliasis due to Angiostrongylus cantonensis (Nematoda: Angiostrongylidae). (19117782)
2009
48
Enzootic angiostrongyliasis in Shenzhen, China. (19046534)
2008
49
Human angiostrongyliasis. (18922484)
2008
50
Optic neuritis caused by intraocular angiostrongyliasis. (19062688)
2008

Variations for Angiostrongyliasis

About this section

Expression for genes affiliated with Angiostrongyliasis

About this section
Search GEO for disease gene expression data for Angiostrongyliasis.

Pathways for genes affiliated with Angiostrongyliasis

About this section

Pathways related to Angiostrongyliasis according to GeneCards Suite gene sharing:

(show all 38)
idSuper pathwaysScoreTop Affiliating Genes
19.6MMP9, PLAU
29.6MMP9, PLAU
39.6MMP9, PLAU
4
Show member pathways
9.6MMP9, PLAU
59.6MMP9, PLAU
6
Show member pathways
9.6IL2, MMP9
79.4IL13, IL2
89.1IL13, IL4
9
Show member pathways
8.8IL13, IL2, IL5
10
Show member pathways
8.8IL13, IL2, IL5
118.8IL2, IL4, MMP9
128.6CCL11, IL4, IL5
138.5IL13, IL4, IL5
148.5IL13, IL4, IL5
15
Show member pathways
8.5IL13, IL4, IL5
16
Show member pathways
8.5IL2, IL4, IL5
178.5IL2, IL4, IL5
188.5IL2, IL4, IL5
19
Show member pathways
8.5IL2, IL4, IL5
208.3CCL11, IL13, IL4, MMP9
21
Show member pathways
8.0IL13, IL2, IL4, IL5
228.0IL13, IL2, IL4, IL5
238.0IL13, IL2, IL4, IL5
248.0IL13, IL2, IL4, IL5
258.0IL13, IL2, IL4, IL5
26
Show member pathways
8.0IL13, IL2, IL4, IL5
27
Show member pathways
8.0IL13, IL2, IL4, IL5
28
Show member pathways
7.7CCL11, IL13, IL4, IL5, MMP9
297.6CCL11, IL13, IL2, IL4, IL5
30
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5
317.6CCL11, IL13, IL2, IL4, IL5
32
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5
33
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5
34
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5
35
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5
367.3CCL11, IL13, IL4, IL5, MMP9, PLAU
37
Show member pathways
7.2CCL11, IL13, IL2, IL4, IL5, MMP9
38
Show member pathways
6.7CCL11, IL13, IL2, IL4, IL5, MMP9

GO Terms for genes affiliated with Angiostrongyliasis

About this section

Cellular components related to Angiostrongyliasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055767.5CCL11, IL13, IL2, IL4, IL5, MMP9
2extracellular spaceGO:00056156.7CCL11, IL13, IL2, IL4, IL5, MMP9

Biological processes related to Angiostrongyliasis according to GeneCards Suite gene sharing:

(show all 21)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of immunoglobulin secretionGO:005102410.0IL2, IL5
2positive regulation of cell migrationGO:00303359.9CCL11, MMP9, PLAU
3extrinsic apoptotic signaling pathway in absence of ligandGO:00971929.9IL2, IL4
4microglial cell activationGO:00017749.8IL13, IL4
5negative regulation of complement-dependent cytotoxicityGO:19036609.8IL13, IL4
6negative regulation of endothelial cell apoptotic processGO:20003529.8IL13, IL4
7negative regulation of T-helper 17 cell differentiationGO:20003209.8IL2, IL4
8positive regulation of activated T cell proliferationGO:00421049.8IL2, IL4
9positive regulation of immunoglobulin productionGO:00026399.8IL13, IL4
10positive regulation of isotype switching to IgG isotypesGO:00483049.8IL2, IL4
11positive regulation of mast cell degranulationGO:00433069.8IL13, IL4
12positive regulation of T cell differentiationGO:00455829.7IL2, IL4
13positive regulation of tyrosine phosphorylation of STAT proteinGO:00425319.7IL2, IL4
14positive regulation of tyrosine phosphorylation of Stat5 proteinGO:00425239.7IL2, IL4
15regulation of proton transportGO:00101559.7IL13, IL4
16inflammatory responseGO:00069549.6CCL11, IL13, IL5
17chemotaxisGO:00069359.5CCL11, IL4, PLAU
18positive regulation of protein phosphorylationGO:00019349.3IL2, IL4, MMP9
19positive regulation of B cell proliferationGO:00308908.7IL13, IL2, IL4, IL5
20response to ethanolGO:00454718.6IL13, IL2, IL4
21immune responseGO:00069558.3CCL11, IL13, IL2, IL4, IL5

Molecular functions related to Angiostrongyliasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine receptor bindingGO:00051269.7IL13, IL4
2growth factor activityGO:00080838.5IL2, IL4, IL5
3cytokine activityGO:00051258.2CCL11, IL13, IL2, IL4, IL5

Sources for Angiostrongyliasis

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet