MCID: ANG002
MIFTS: 43

Angiostrongyliasis malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Angiostrongyliasis

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Sources:
10Disease Ontology, 45NIH Rare Diseases, 12DISEASES, 51Orphanet, 65UMLS, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet, 27ICD10
See all MalaCards sources

Aliases & Descriptions for Angiostrongyliasis:

Name: Angiostrongyliasis 10 45 12 51 65

Classifications:



External Ids:

Disease Ontology10 DOID:0050256
Orphanet51 74
ICD10 via Orphanet28 B81.3, B83.2
MESH via Orphanet37 C536369
UMLS via Orphanet66 C0392662
ICD1027 B83.2
UMLS65 C0392662

Summaries for Angiostrongyliasis

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Disease Ontology:10 A parasitic helminthiasis infectious disease that involves parasitic infection of the intestine, central nervous system and eyes by Angiostrongylus cantonensis or Angiostrongylus costaricensis.

MalaCards based summary: Angiostrongyliasis is related to adult epithelioid sarcoma and conjunctival disease. An important gene associated with Angiostrongyliasis is MMP9 (Matrix Metallopeptidase 9), and among its related pathways are FGF signaling pathway and Validated transcriptional targets of AP1 family members Fra1 and Fra2. Affiliated tissues include kidney, eye and breast, and related mouse phenotypes are tumorigenesis and liver/biliary system.

Wikipedia:68 Angiostrongyliasis is an infection by a nematode from the Angiostrongylus genus of kidney and alimentary... more...

Related Diseases for Angiostrongyliasis

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Diseases related to Angiostrongyliasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 101)
idRelated DiseaseScoreTop Affiliating Genes
1adult epithelioid sarcoma10.5MMP9, PLAU
2conjunctival disease10.5MMP9, PLAU
3meningitis10.4
4eosinophilic meningitis10.4
5neonatal infective mastitis10.4IL5, PLAU
6pars planitis10.3IL13, IL5
7antley-bixler syndrome with genital anomalies and disordered steroidogenesis10.3IL13, IL5
8steatorrhea10.3IL13, IL5
9hypertensive encephalopathy10.3IL4, MMP9
10timothy grass allergy10.2IL13, IL5
11kyphoscoliotic heart disease10.2IL4, IL5
12gonococcal bursitis10.2IL4, IL5
13central nervous system childhood germ cell tumor10.2IL13, IL5
14breast disease10.2MMP9, PLAU
15status asthmaticus10.2IL4, IL5
16idiopathic interstitial pneumonia10.2IL4, IL5
17retroperitoneal germ cell neoplasm10.2IL13, IL5
18bronchopulmonary dysplasia10.2IL13, MMP9
19superficial urinary bladder cancer10.2IL4, IL5
20mobitz type ii atrioventricular block10.2IL4, IL5
21granulomatous amebic encephalitis10.2IL4, IL5
22hepatitis e10.2IL4, IL5
23primary progressive multiple sclerosis10.2IL4, MMP9
24penicillin allergy10.2IL13, IL4
25prepuce cancer10.1IL4, IL5
26extrapulmonary tuberculosis10.1IL13, IL4
27cow milk allergy10.1IL13, IL4
28optic neuritis10.1
29neuritis10.1
30blepharophimosis10.0IL5, MMP9, SNAI2
31postmenopausal atrophic vaginitis10.0IL13, IL5
32meningoencephalitis10.0
33appendicitis10.0
34tracheal cancer10.0MMP9, PLAU, SNAI2
35demyelinating disease10.0IL2, MMP9
36female breast central part cancer9.9IL2, IL5
37acute gonococcal epididymo-orchitis9.9IL2, IL5
38deafness, autosomal recessive 629.9IL4, IL5
39cd45 deficiency9.9IL2, IL4
40maxillary neoplasm9.8IL2, IL4
41anisakiasis9.8
42meckel's diverticulum9.8
43eosinophilia9.8
44collagenous colitis9.8IL2, IL4
45b cell deficiency9.8IL2, IL4
46vulvovaginitis9.8IL2, IL4
47chronic conjunctivitis9.8IL2, IL4
48benign paroxysmal positional nystagmus9.8IL13, IL4, IL5
49eosinophilic gastroenteritis9.8IL13, IL4, IL5
50motor peripheral neuropathy9.8IL13, IL4, IL5

Graphical network of the top 20 diseases related to Angiostrongyliasis:



Diseases related to angiostrongyliasis

Symptoms for Angiostrongyliasis

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Drugs & Therapeutics for Angiostrongyliasis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Angiostrongyliasis

Genetic Tests for Angiostrongyliasis

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Anatomical Context for Angiostrongyliasis

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MalaCards organs/tissues related to Angiostrongyliasis:

33
Kidney, Eye, Breast, Thyroid, Heart, Colon, Myeloid

Animal Models for Angiostrongyliasis or affiliated genes

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MGI Mouse Phenotypes related to Angiostrongyliasis:

38 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.8IL2, IL5, MMP9, PLAU
2MP:00053708.6IL2, IL4, IL5, PLAU
3MP:00053908.0IL13, IL4, MMP9, PLAU, SNAI2
4MP:00053798.0IL13, IL2, IL4, PLAU, SNAI2
5MP:00053887.6IL13, IL2, IL4, IL5, MMP9, PLAU
6MP:00053897.1IL13, IL2, IL4, IL5, MMP9, PLAU
7MP:00053817.0IL13, IL2, IL4, IL5, MMP9, PLAU
8MP:00053766.9IL13, IL2, IL4, IL5, MMP9, PLAU
9MP:00053786.8IL13, IL2, IL4, IL5, MMP9, PLAU
10MP:00053876.6IL13, IL2, IL4, IL5, MMP9, PLAU
11MP:00053976.4IL13, IL2, IL4, IL5, MMP9, PLAU

Publications for Angiostrongyliasis

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Articles related to Angiostrongyliasis:

(show top 50)    (show all 137)
idTitleAuthorsYear
1
Abdominal angiostrongyliasis mimicking acute appendicitis. (25928828)
2015
2
Follow-up on anterior chamber angiostrongyliasis. (25124954)
2014
3
Angiostrongyliasis in Thailand: epidemiology and laboratory investigations. (23901379)
2013
4
Intrathecal activation as a typical immune response within the central nervous system in angiostrongyliasis. (23390222)
2013
5
Workshop on research priorities for management and treatment of angiostrongyliasis(1). (23171634)
2012
6
Lung CT findings of angiostrongyliasis cantonensis caused by Angiostrongylus cantonensis. (21513853)
2011
7
An outbreak of angiostrongyliasis in Guanging, People's Republic of China: migrants vulnerable to an emerging disease. (22299428)
2011
8
Treatment of angiostrongyliasis using a combination of albendazole and dexamethasone: the results of a retrospective and comparative study. (21294950)
2011
9
Human ocular angiostrongyliasis: a literature review. (21296846)
2011
10
Comparison of major immunoglobulins intrathecal synthesis patterns in Ecuadorian and Cuban patients with angiostrongyliasis. (21363978)
2011
11
Outcomes in mice with abdominal angiostrongyliasis treated with enoxaparin. (21400113)
2011
12
Application of recombinant SMR-domain containing protein of angiostrongylus cantonensis in immunoblot diagnosis of human angiostrongyliasis. (21073053)
2010
13
Abdominal angiostrongyliasis caused by Angiostrongylus cantonensis: a possible cause of eosinophilic infiltration in human digestive tract. (19545957)
2010
14
Human angiostrongyliasis outbreak in Dali, China. (19771154)
2009
15
Immunological diagnosis of human angiostrongyliasis due to Angiostrongylus cantonensis (Nematoda: Angiostrongylidae). (19117782)
2009
16
Individual serological follow-up of patients with suspected or confirmed abdominal angiostrongyliasis. (18327506)
2008
17
Abdominal angiostrongyliasis in rodent experimental infection: evidence for systemic circulation of first stage larvae. (17561438)
2007
18
Cerebrospinal fluid eotaxin and eotaxin-2 levels in human eosinophilic meningitis associated with angiostrongyliasis. (17703945)
2007
19
Ocular angiostrongyliasis in a child--first case report from India. (16186138)
2006
20
Abdominal angiostrongyliasis: a case with severe evolution. (16553328)
2005
21
Ocular Angiostrongyliasis: removal of a live nematode from the anterior chamber. (15232595)
2005
22
Angiostrongyliasis, Mainland China. (16355510)
2005
23
Ocular parastrongyliasis (=angiostrongyliasis): probable first report of human infection from a patient in Ceylon (Sri Lanka). (15828436)
2004
24
Diagnosis of abdominal angiostrongyliasis by PCR from sera of patients. (14743672)
2003
25
First report of human angiostrongyliasis acquired in Sydney. (14558868)
2003
26
Evaluation of human IgG subclass antibodies in the serodiagnosis of angiostrongyliasis. (12658452)
2003
27
Ocular angiostrongyliasis without meningitis symptoms in Okinawa, Japan. (12053973)
2002
28
Angiostrongyliasis: analysis of antigens of Angiostrongylus costaricensis adult worms versus IgG from infected patients with Angiostrongylus cantonensis. (11414459)
2000
29
Jejunal perforation caused by abdominal angiostrongyliasis. (10602548)
1999
30
Seroepidemiology of abdominal angiostrongyliasis: the standardization of an immunoenzymatic assay and prevalence of antibodies in two localities in southern Brazil. (9491104)
1997
31
Detection of circulating antigen by monoclonal antibodies for immunodiagnosis of angiostrongyliasis. (9158049)
1997
32
Angiostrongyliasis in a European patient: a rare cause of gangrenous ischemic enterocolitis. (8224660)
1993
33
Human anisakiasis misdiagnosed as abdominal angiostrongyliasis. (8443320)
1993
34
Clinical studies on angiostrongyliasis cantonensis among children in Taiwan. (1822885)
1991
35
Clinical and epidemiological aspects of abdominal angiostrongyliasis in southern Brazil. (1844964)
1991
36
Immunodiagnosis of angiostrongyliasis with monoclonal antibodies recognizing a circulating antigen of mol. wt 91,000 from Angiostrongylus cantonensis. (1869351)
1991
37
Histopathological criteria for the diagnosis of abdominal angiostrongyliasis. (1792232)
1991
38
Abdominal angiostrongyliasis: a problem of public health. (15275575)
1985
39
ELISA testing in cases of clinical angiostrongyliasis in Thailand. (4023800)
1985
40
Eosinophilic radiculomyeloencephalitis: an angiostrongyliasis outbreak in American Samoa related to ingestion of Achatina fulica snails. (7149098)
1982
41
Three cases of worm proven human angiostrongyliasis in Taiwan. (7343202)
1981
42
Angiostrongyliasis in Australia. (6930222)
1980
43
Clinical observations and immunodiagnosis of angiostrongyliasis in North Taiwan. (7219318)
1980
44
Angiostrongyliasis cantonensis. (287448)
1979
45
Pathological findings in four cases of human angiostrongyliasis. (725653)
1978
46
Angiostrongyliasis in Indonesia: additional geographic and host occurrence records. (751218)
1978
47
Ocular angiostrongyliasis in Semarang, Central Java. (842785)
1977
48
Case of ocular angiostrongyliasis associated with eosinophilic meningitis. (5102754)
1971
49
Eosinophilic meningoencephalitis caused by angiostrongyliasis in Thailand. Autopsy report. (4952148)
1967
50
Second case of ocular angiostrongyliasis in Thailand. (5901630)
1966

Variations for Angiostrongyliasis

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Expression for genes affiliated with Angiostrongyliasis

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Search GEO for disease gene expression data for Angiostrongyliasis.

Pathways for genes affiliated with Angiostrongyliasis

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Pathways related to Angiostrongyliasis according to GeneCards Suite gene sharing:

(show all 28)
idSuper pathwaysScoreTop Affiliating Genes
19.7MMP9, PLAU
29.7MMP9, PLAU
39.7MMP9, PLAU
49.7MMP9, PLAU
59.7MMP9, PLAU
69.7MMP9, PLAU
79.7MMP9, PLAU
89.4IL4, IL5
99.4IL4, IL5
109.1IL13, IL2
118.9IL13, IL4, IL5
12
Show member pathways
8.9IL13, IL4, IL5
13
Show member pathways
8.7IL13, IL2, IL5
14
Show member pathways
8.7IL13, IL2, IL5
158.7IL2, IL4, MMP9
16
Show member pathways
8.6IL2, IL4, IL5
17
Show member pathways
8.6IL2, IL4, IL5
188.6IL2, IL4, IL5
198.6IL2, IL4, IL5
208.1IL13, IL2, IL4, IL5
218.1IL13, IL2, IL4, IL5
228.1IL13, IL2, IL4, IL5
238.1IL13, IL2, IL4, IL5
24
Show member pathways
8.1IL13, IL2, IL4, IL5
25
Show member pathways
8.1IL13, IL2, IL4, IL5
268.1IL13, IL2, IL4, IL5
27
Show member pathways
8.1IL13, IL2, IL4, IL5
28
Show member pathways
7.5IL13, IL2, IL4, IL5, SNAI2

GO Terms for genes affiliated with Angiostrongyliasis

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Biological processes related to Angiostrongyliasis according to GeneCards Suite gene sharing:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1embryo implantationGO:000756610.2MMP9, PLAU
2negative regulation of complement-dependent cytotoxicityGO:190366010.0IL13, IL4
3regulation of proton transportGO:001015510.0IL13, IL4
4positive regulation of mast cell degranulationGO:004330610.0IL13, IL4
5positive regulation of immunoglobulin productionGO:00026399.9IL13, IL4
6positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.8IL4, IL5
7positive regulation of peptidyl-tyrosine phosphorylationGO:00507319.8IL4, IL5
8microglial cell activationGO:00017749.7IL13, IL4
9positive regulation of T cell differentiationGO:00455829.6IL2, IL4
10extrinsic apoptotic signaling pathway in absence of ligandGO:00971929.6IL2, IL4
11positive regulation of tyrosine phosphorylation of Stat5 proteinGO:00425239.6IL2, IL4
12positive regulation of T cell proliferationGO:00421029.5IL2, IL4
13positive regulation of isotype switching to IgG isotypesGO:00483049.4IL2, IL4
14positive regulation of B cell proliferationGO:00308908.6IL13, IL2, IL4, IL5
15positive regulation of cell proliferationGO:00082848.6IL2, IL4, IL5
16negative regulation of apoptotic processGO:00430668.1IL2, IL4, MMP9, SNAI2
17immune responseGO:00069557.8IL13, IL2, IL4, IL5

Sources for Angiostrongyliasis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet