MCID: ANG002
MIFTS: 39

Angiostrongyliasis malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Angiostrongyliasis

Aliases & Descriptions for Angiostrongyliasis:

Name: Angiostrongyliasis 12 50 56 14 69

Classifications:

Orphanet: 56  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:0050256
Orphanet 56 ORPHA74
ICD10 via Orphanet 34 B81.3 B83.2
MESH via Orphanet 43 C536369
UMLS via Orphanet 70 C0392662
ICD10 33 B83.2

Summaries for Angiostrongyliasis

Disease Ontology : 12 A parasitic helminthiasis infectious disease that involves parasitic infection of the intestine, central nervous system and eyes by Angiostrongylus cantonensis or Angiostrongylus costaricensis.

MalaCards based summary : Angiostrongyliasis is related to meningitis and eosinophilic meningitis. An important gene associated with Angiostrongyliasis is MMP9 (Matrix Metallopeptidase 9), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. Affiliated tissues include eye, kidney and testes, and related phenotypes are digestive/alimentary and hematopoietic system

Wikipedia : 71 Angiostrongyliasis is an infection by a nematode from the Angiostrongylus genus of kidney and alimentary... more...

Related Diseases for Angiostrongyliasis

Diseases related to Angiostrongyliasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 126)
id Related Disease Score Top Affiliating Genes
1 meningitis 10.3
2 eosinophilic meningitis 10.2
3 nonossifying fibromyxoid tumor 10.2 MMP9 PLAU
4 retinal artery occlusion 10.2 CCL11 MMP9
5 peptidic growth factors deficiency 10.1 CCL11 IL5
6 latent syphilis 10.1 CCL11 IL5
7 necrotizing gastritis 10.1 CCL11 IL5
8 dahlberg borer newcomer syndrome 10.1 IL13 IL5
9 aortic atherosclerosis 10.1 IL13 IL5
10 renal hypertension 10.1 IL13 IL5
11 hypercementosis 10.1 IL13 IL5
12 exudative vitreoretinopathy 2, x-linked 10.1 IL13 IL5
13 stickler syndrome, type v 10.1 IL2 MMP9
14 smooth muscle tumor 10.1 IL13 IL5
15 ectropion 10.1 IL4 MMP9
16 prostate small cell carcinoma 10.1 IL13 IL5
17 psychotic disorder 10.0 CCL11 IL4
18 anterior dislocation of lens 10.0 CCL11 IL4
19 retinal vascular disease 10.0 CCL11 IL4
20 metal allergy 10.0 IL13 IL5
21 inclusion conjunctivitis 10.0 IL2 IL5
22 sarcoma 10.0 IL2 IL4
23 vulvar vestibulitis syndrome 10.0 IL2 IL4
24 autosomal dominant deafness-onychodystrophy syndrome 10.0 IL2 IL4
25 ovarian mucinous neoplasm 10.0 IL13 IL5
26 crustacean allergy 10.0 IL13 IL4
27 goat milk allergy 10.0 IL13 IL4
28 wilkes stevenson syndrome 10.0 IL2 IL5
29 clostridium difficile colitis 10.0 IL2 IL4
30 gonadal disease 10.0 IL2 IL4
31 marasmus 10.0 IL4 IL5
32 opitz-kaveggia syndrome 10.0 IL2 IL4
33 papillary squamous carcinoma 10.0 IL4 IL5
34 lens-induced iridocyclitis 10.0 IL4 IL5
35 hypersensitivity vasculitis 10.0 IL4 IL5
36 tularemia 10.0 IL2 IL4
37 optic neuritis 10.0
38 neuritis 10.0
39 spastic diplegia 10.0 CCL11 IL13 IL5
40 allescheriosis 10.0 IL4 IL5
41 disordered steroidogenesis due to cytochrome p450 oxidoreductase 9.9 CCL11 IL13 IL5
42 central nervous system origin vertigo 9.9 IL2 IL4
43 breast intracanalicular fibroadenoma 9.9 IL4 IL5
44 childhood malignant mesenchymoma 9.9 CCL11 IL13 IL5
45 histoplasmosis retinitis 9.9 IL4 IL5
46 conjunctival concretion 9.9 CCL11 IL13 IL5
47 birth defects 9.9 CCL11 IL13 IL5
48 acute myeloid leukemia with recurrent genetic anomaly 9.9 IL2 IL4
49 rectum squamous cell carcinoma 9.9 CCL11 IL13 IL5
50 isolated klippel-feil syndrome 9.9 IL4 IL5

Graphical network of the top 20 diseases related to Angiostrongyliasis:



Diseases related to Angiostrongyliasis

Symptoms & Phenotypes for Angiostrongyliasis

MGI Mouse Phenotypes related to Angiostrongyliasis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.88 MMP9 IL13 PLAU IL2 IL4 IL5
2 hematopoietic system MP:0005397 9.87 CCL11 MMP9 IL13 PLAU IL2 IL4
3 growth/size/body region MP:0005378 9.85 MMP9 IL13 PLAU IL2 IL4 IL5
4 immune system MP:0005387 9.8 CCL11 MMP9 IL13 PLAU IL2 IL4
5 neoplasm MP:0002006 9.46 MMP9 PLAU IL2 IL5
6 reproductive system MP:0005389 9.43 MMP9 IL13 PLAU IL2 IL4 IL5
7 respiratory system MP:0005388 9.17 IL13 PLAU IL2 IL4 IL5 CCL11

Drugs & Therapeutics for Angiostrongyliasis

Search Clinical Trials , NIH Clinical Center for Angiostrongyliasis

Genetic Tests for Angiostrongyliasis

Anatomical Context for Angiostrongyliasis

MalaCards organs/tissues related to Angiostrongyliasis:

39
Eye, Kidney, Testes, Lung, Skin, Liver, Colon

Publications for Angiostrongyliasis

Articles related to Angiostrongyliasis:

(show top 50) (show all 139)
id Title Authors Year
1
First Evidence of Angiostrongyliasis Caused by Angiostrongylus cantonensis in Guadeloupe, Lesser Antilles. ( 28070007 )
2017
2
Cloning and expression of a 16-kDa recombinant protein from Angiostrongylus cantonensis for use in immunoblot diagnosis of human angiostrongyliasis. ( 27406573 )
2016
3
A Case of Ocular Angiostrongyliasis with Molecular Identification of the Species in Vietnam. ( 26797438 )
2015
4
Abdominal angiostrongyliasis mimicking acute appendicitis. ( 25928828 )
2015
5
Emergence of neural angiostrongyliasis in eastern australia. ( 25793473 )
2015
6
Follow-up on anterior chamber angiostrongyliasis. ( 25124954 )
2014
7
PCR for the diagnosis of abdominal angiostrongyliasis in formalin-fixed paraffin-embedded human tissue. ( 24705328 )
2014
8
Acute eosinophilic meningitis and orbital inflammation from presumed angiostrongyliasis. ( 24862785 )
2014
9
Intrathecal activation as a typical immune response within the central nervous system in angiostrongyliasis. ( 23390222 )
2013
10
Angiostrongyliasis in Thailand: epidemiology and laboratory investigations. ( 23901379 )
2013
11
The role of eosinophils in angiostrongyliasis: multiple roles for a versatile cell? ( 23901384 )
2013
12
Comprehensive review of ocular angiostrongyliasis with special reference to optic neuritis. ( 24516263 )
2013
13
Anterior chamber angiostrongyliasis. ( 23846206 )
2013
14
Differential diagnosis of CNS angiostrongyliasis: a short review. ( 23901385 )
2013
15
Pathways for transmission of angiostrongyliasis and the risk of disease associated with them. ( 23901388 )
2013
16
Endemic angiostrongyliasis in the Brazilian Amazon: natural parasitism of Angiostrongylus cantonensis in Rattus rattus and R. norvegicus, and sympatric giant African land snails, Achatina fulica. ( 23072946 )
2013
17
Neuroimaging features in neuro-gnathostomiasis and angiostrongyliasis. ( 22271262 )
2013
18
Subretinal angiostrongyliasis-induced optic neuritis. ( 23818750 )
2013
19
A comparative study of neuroimaging features between human neuro-gnathostomiasis and angiostrongyliasis. ( 22124854 )
2012
20
How can clinicians ensure the diagnosis of meningitic angiostrongyliasis? ( 21923259 )
2012
21
Enzootic angiostrongyliasis in Guangzhou, China, 2008-2010. ( 22556086 )
2012
22
Workshop on research priorities for management and treatment of angiostrongyliasis(1). ( 23171634 )
2012
23
Endemic angiostrongyliasis, Rio de Janeiro, Brazil. ( 21762612 )
2011
24
Comparison of major immunoglobulins intrathecal synthesis patterns in Ecuadorian and Cuban patients with angiostrongyliasis. ( 21363978 )
2011
25
Lung CT findings of angiostrongyliasis cantonensis caused by Angiostrongylus cantonensis. ( 21513853 )
2011
26
Abdominal angiostrongyliasis with involvement of liver histopathologically confirmed: a case report. ( 21915466 )
2011
27
An outbreak of angiostrongyliasis in Guanging, People's Republic of China: migrants vulnerable to an emerging disease. ( 22299428 )
2011
28
International symposium on Angiostrongylus and Angiostrongyliasis, 2010. ( 21762566 )
2011
29
Treatment of angiostrongyliasis using a combination of albendazole and dexamethasone: the results of a retrospective and comparative study. ( 21294950 )
2011
30
Enzootic angiostrongyliasis, Guangdong, China, 2008-2009. ( 21762614 )
2011
31
Human ocular angiostrongyliasis: a literature review. ( 21296846 )
2011
32
Development of a double antibody sandwich ELISA assay for the diagnosis of angiostrongyliasis. ( 21506824 )
2011
33
An indirect immunofluorescence antibody test employing whole eggs as the antigen for the diagnosis of abdominal angiostrongyliasis. ( 21739024 )
2011
34
Outcomes in mice with abdominal angiostrongyliasis treated with enoxaparin. ( 21400113 )
2011
35
Peripheral eosinophilia as an indicator of meningitic angiostrongyliasis in exposed individuals. ( 21120370 )
2010
36
Application of recombinant SMR-domain containing protein of angiostrongylus cantonensis in immunoblot diagnosis of human angiostrongyliasis. ( 21073053 )
2010
37
Abdominal angiostrongyliasis caused by Angiostrongylus cantonensis: a possible cause of eosinophilic infiltration in human digestive tract. ( 19545957 )
2010
38
Identification of factors associated with clinically severe angiostrongyliasis. ( 21118948 )
2010
39
Cerebrospinal fluid u-plasminogen activator and matrix metalloproteinase-9 levels in human eosinophilic meningitis associated with angiostrongyliasis. ( 20584616 )
2010
40
Use of heterologous antigens for the immunodiagnosis of abdominal angiostrongyliasis by an enzyme-linked immunosorbent assay. ( 21120363 )
2010
41
Human angiostrongyliasis outbreak in Dali, China. ( 19771154 )
2009
42
Colon mass secondary to angiostrongyliasis. ( 19345351 )
2009
43
Ocular angiostrongyliasis--first case report from Jamaica. ( 20099782 )
2009
44
Angiostrongyliasis in the Americas. ( 19523320 )
2009
45
Abdominal angiostrongyliasis: what does the rheumatologist must know about it? ( 20374358 )
2009
46
Thai koi-hoi snail dish and angiostrongyliasis due to Angiostrongylus cantonensis: Effects of food flavoring and alcoholic drink on the third-stage larvae in infected snail meat. ( 19272010 )
2009
47
Immunological diagnosis of human angiostrongyliasis due to Angiostrongylus cantonensis (Nematoda: Angiostrongylidae). ( 19117782 )
2009
48
Enzootic angiostrongyliasis in Shenzhen, China. ( 19046534 )
2008
49
Human angiostrongyliasis. ( 18922484 )
2008
50
Optic neuritis caused by intraocular angiostrongyliasis. ( 19062688 )
2008

Variations for Angiostrongyliasis

Expression for Angiostrongyliasis

Search GEO for disease gene expression data for Angiostrongyliasis.

Pathways for Angiostrongyliasis

Pathways related to Angiostrongyliasis according to GeneCards Suite gene sharing:

(show all 38)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.73 CCL11 IL13 IL2 IL4 IL5 MMP9
2
Show member pathways
13.39 CCL11 IL13 IL2 IL4 IL5
3
Show member pathways
13.28 CCL11 IL13 IL2 IL4 IL5
4
Show member pathways
13.17 CCL11 IL13 IL2 IL4 IL5
5
Show member pathways
13.15 CCL11 IL13 IL2 IL4 IL5 MMP9
6
Show member pathways
13.08 CCL11 IL13 IL2 IL4 IL5
7
Show member pathways
12.67 CCL11 IL13 IL2 IL4 IL5
8
Show member pathways
12.42 IL13 IL2 IL4 IL5
9
Show member pathways
12.38 IL13 IL4 IL5
10
Show member pathways
12.24 IL13 IL2 IL5
11
Show member pathways
12.23 IL2 IL4 IL5
12
Show member pathways
12.1 CCL11 IL13 IL4 IL5 MMP9
13
Show member pathways
12.09 IL13 IL2 IL4 IL5
14
Show member pathways
12.01 IL13 IL2 IL4 IL5
15
Show member pathways
11.88 IL13 IL2 IL5
16 11.86 IL2 IL4 MMP9
17 11.84 IL2 IL4 IL5
18 11.84 CCL11 IL13 IL4 MMP9
19 11.65 IL13 IL2 IL4 IL5
20
Show member pathways
11.63 IL2 IL4 IL5
21 11.61 IL13 IL2 IL4 IL5
22 11.54 CCL11 IL4 IL5
23
Show member pathways
11.48 IL2 MMP9
24 11.46 MMP9 PLAU
25 11.36 IL13 IL4
26 11.34 MMP9 PLAU
27 11.33 MMP9 PLAU
28
Show member pathways
11.3 MMP9 PLAU
29 11.22 IL2 IL4 IL5
30 11.19 IL13 IL4 IL5
31 11.16 MMP9 PLAU
32 11.08 IL13 IL2
33 11.03 IL13 IL2 IL4 IL5
34 11.03 CCL11 IL13 IL2 IL4 IL5
35 10.95 CCL11 IL13 IL2 IL4 IL5
36 10.9 CCL11 IL13 IL4 IL5 MMP9 PLAU
37 10.87 IL13 IL2 IL4 IL5
38 10.81 IL13 IL4 IL5

GO Terms for Angiostrongyliasis

Cellular components related to Angiostrongyliasis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.5 CCL11 IL13 IL2 IL4 IL5 MMP9
2 extracellular space GO:0005615 9.17 CCL11 IL13 IL2 IL4 IL5 MMP9

Biological processes related to Angiostrongyliasis according to GeneCards Suite gene sharing:

(show all 21)
id Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.77 CCL11 IL13 IL5
2 positive regulation of cell migration GO:0030335 9.73 CCL11 MMP9 PLAU
3 chemotaxis GO:0006935 9.7 CCL11 IL4 PLAU
4 positive regulation of protein phosphorylation GO:0001934 9.69 IL2 IL4 MMP9
5 response to ethanol GO:0045471 9.63 IL13 IL2 IL4
6 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.59 IL2 IL4
7 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.58 IL2 IL4
8 negative regulation of endothelial cell apoptotic process GO:2000352 9.58 IL13 IL4
9 positive regulation of activated T cell proliferation GO:0042104 9.57 IL2 IL4
10 positive regulation of T cell differentiation GO:0045582 9.55 IL2 IL4
11 positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 9.54 IL2 IL4
12 microglial cell activation GO:0001774 9.49 IL13 IL4
13 positive regulation of immunoglobulin secretion GO:0051024 9.48 IL2 IL5
14 positive regulation of isotype switching to IgG isotypes GO:0048304 9.43 IL2 IL4
15 positive regulation of mast cell degranulation GO:0043306 9.4 IL13 IL4
16 positive regulation of immunoglobulin production GO:0002639 9.37 IL13 IL4
17 immune response GO:0006955 9.35 CCL11 IL13 IL2 IL4 IL5
18 regulation of proton transport GO:0010155 9.32 IL13 IL4
19 negative regulation of T-helper 17 cell differentiation GO:2000320 9.26 IL2 IL4
20 negative regulation of complement-dependent cytotoxicity GO:1903660 9.16 IL13 IL4
21 positive regulation of B cell proliferation GO:0030890 8.92 IL13 IL2 IL4 IL5

Molecular functions related to Angiostrongyliasis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine receptor binding GO:0005126 9.16 IL13 IL4
2 growth factor activity GO:0008083 9.13 IL2 IL4 IL5
3 cytokine activity GO:0005125 9.02 CCL11 IL13 IL2 IL4 IL5

Sources for Angiostrongyliasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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