MCID: ANG002
MIFTS: 39

Angiostrongyliasis malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Angiostrongyliasis

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Sources:
11Disease Ontology, 13DISEASES, 30ICD10, 31ICD10 via Orphanet, 40MESH via Orphanet, 48NIH Rare Diseases, 54Orphanet, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Angiostrongyliasis:

Name: Angiostrongyliasis 11 48 54 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:0050256
Orphanet54 ORPHA74
ICD10 via Orphanet31 B81.3, B83.2
MESH via Orphanet40 C536369
UMLS via Orphanet69 C0392662
ICD1030 B83.2

Summaries for Angiostrongyliasis

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Disease Ontology:11 A parasitic helminthiasis infectious disease that involves parasitic infection of the intestine, central nervous system and eyes by Angiostrongylus cantonensis or Angiostrongylus costaricensis.

MalaCards based summary: Angiostrongyliasis is related to peritonitis and meningitis. An important gene associated with Angiostrongyliasis is MMP9 (Matrix Metallopeptidase 9), and among its related pathways are Validated transcriptional targets of AP1 family members Fra1 and Fra2 and Osteopontin-mediated events. Affiliated tissues include eye, kidney and testes, and related mouse phenotypes are neoplasm and digestive/alimentary.

Wikipedia:71 Angiostrongyliasis is an infection by a nematode from the Angiostrongylus genus of kidney and alimentary... more...

Related Diseases for Angiostrongyliasis

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Diseases related to Angiostrongyliasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 132)
idRelated DiseaseScoreTop Affiliating Genes
1peritonitis10.4MMP9, PLAU
2meningitis10.2
3jejunal somatostatinoma10.2IL2, MMP9
4giant ganglionic hyperplasia10.2CCL11, IL5
5iridocyclitis10.2CCL11, IL2
6eosinophilic meningitis10.2
7fungal gastritis10.2CCL11, IL5
8benign mammary dysplasia10.2CCL11, IL5
9cytoplasmic body myopathy10.1IL13, IL5
10aortic arch interruption10.1IL13, IL5
11toxic diffuse goiter10.1IL13, IL5
12cherry allergy10.1IL13, IL5
13skin disease10.1IL13, IL5
14urinary bladder small cell neuroendocrine carcinoma10.1IL13, IL5
15polyradiculoneuropathy10.1IL13, IL5
16mechanical ectropion10.1IL4, MMP9
17vaginal squamous tumor10.1IL2, IL5
18autoimmune neuropathy10.1IL13, IL5
19pediatric germ cell cancer10.1IL13, IL5
20papillary conjunctivitis10.1CCL11, IL4
21anterior dislocation of lens10.0CCL11, IL4
22retinal vascular disease10.0CCL11, IL4
23gastric ulcer10.0IL2, IL5
24progressive relapsing multiple sclerosis10.0IL4, MMP9
25juvenile dermatitis herpetiformis10.0CCL11, IL4
26visual snow syndrome10.0IL2, IL4
27nervous system cancer10.0IL4, MMP9
28goat milk allergy9.9IL13, IL4
29optic neuritis9.9
30neuritis9.9
31interleukin-7 receptor alpha deficiency9.9IL2, IL4
32cow milk allergy9.9IL13, IL4
33alternating exotropia9.9IL2, IL5
34abdominal tuberculosis9.9IL13, IL4
35lipodermatosclerosis9.9IL2, IL4
36pneumonic tularemia9.9IL2, IL4
37blepharochalasis9.9MMP9, PLAU
38pharyngitis9.9IL2, IL4
39subacute lymphocytic thyroiditis9.9IL2, IL4
40keratoconjunctivitis9.9IL4, IL5
41chronic pulmonary heart disease9.9IL4, IL5
42common cold9.9IL2, IL4
43esophagus melanoma9.9IL2, IL4
44meningoencephalitis9.9
45appendicitis9.9
46bacteriuria9.9IL2, IL4
47myositis fibrosa9.9IL4, IL5
48acute conjunctivitis9.8IL4, IL5
49african histoplasmosis9.8IL4, IL5
50spermatic cord cancer9.8IL4, IL5

Graphical network of the top 20 diseases related to Angiostrongyliasis:



Diseases related to angiostrongyliasis

Symptoms & Phenotypes for Angiostrongyliasis

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MGI Mouse Phenotypes related to Angiostrongyliasis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020069.3IL2, IL5, MMP9, PLAU
2MP:00053818.0IL13, IL2, IL4, IL5, MMP9, PLAU
3MP:00053788.0IL13, IL2, IL4, IL5, MMP9, PLAU
4MP:00053897.9IL13, IL2, IL4, IL5, MMP9, PLAU
5MP:00053977.6CCL11, IL13, IL2, IL4, IL5, MMP9
6MP:00053877.5CCL11, IL13, IL2, IL4, IL5, MMP9
7MP:00053886.7CCL11, IL13, IL2, IL4, IL5, MMP9

Drugs & Therapeutics for Angiostrongyliasis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Angiostrongyliasis

Genetic Tests for Angiostrongyliasis

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Anatomical Context for Angiostrongyliasis

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MalaCards organs/tissues related to Angiostrongyliasis:

36
Eye, Kidney, Testes, Skin, Liver, Colon, Lung

Publications for Angiostrongyliasis

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Articles related to Angiostrongyliasis:

(show top 50)    (show all 139)
idTitleAuthorsYear
1
First Evidence of Angiostrongyliasis Caused by Angiostrongylus cantonensis in Guadeloupe, Lesser Antilles. (28070007)
2017
2
Cloning and expression of a 16-kDa recombinant protein from Angiostrongylus cantonensis for use in immunoblot diagnosis of human angiostrongyliasis. (27406573)
2016
3
Abdominal angiostrongyliasis mimicking acute appendicitis. (25928828)
2015
4
A Case of Ocular Angiostrongyliasis with Molecular Identification of the Species in Vietnam. (26797438)
2015
5
Emergence of neural angiostrongyliasis in eastern australia. (25793473)
2015
6
Acute eosinophilic meningitis and orbital inflammation from presumed angiostrongyliasis. (24862785)
2014
7
Follow-up on anterior chamber angiostrongyliasis. (25124954)
2014
8
PCR for the diagnosis of abdominal angiostrongyliasis in formalin-fixed paraffin-embedded human tissue. (24705328)
2014
9
Anterior chamber angiostrongyliasis. (23846206)
2013
10
Endemic angiostrongyliasis in the Brazilian Amazon: natural parasitism of Angiostrongylus cantonensis in Rattus rattus and R. norvegicus, and sympatric giant African land snails, Achatina fulica. (23072946)
2013
11
Comprehensive review of ocular angiostrongyliasis with special reference to optic neuritis. (24516263)
2013
12
Subretinal angiostrongyliasis-induced optic neuritis. (23818750)
2013
13
Differential diagnosis of CNS angiostrongyliasis: a short review. (23901385)
2013
14
Angiostrongyliasis in Thailand: epidemiology and laboratory investigations. (23901379)
2013
15
Intrathecal activation as a typical immune response within the central nervous system in angiostrongyliasis. (23390222)
2013
16
Pathways for transmission of angiostrongyliasis and the risk of disease associated with them. (23901388)
2013
17
The role of eosinophils in angiostrongyliasis: multiple roles for a versatile cell? (23901384)
2013
18
Neuroimaging features in neuro-gnathostomiasis and angiostrongyliasis. (22271262)
2013
19
Workshop on research priorities for management and treatment of angiostrongyliasis(1). (23171634)
2012
20
How can clinicians ensure the diagnosis of meningitic angiostrongyliasis? (21923259)
2012
21
A comparative study of neuroimaging features between human neuro-gnathostomiasis and angiostrongyliasis. (22124854)
2012
22
Enzootic angiostrongyliasis in Guangzhou, China, 2008-2010. (22556086)
2012
23
Lung CT findings of angiostrongyliasis cantonensis caused by Angiostrongylus cantonensis. (21513853)
2011
24
An outbreak of angiostrongyliasis in Guanging, People's Republic of China: migrants vulnerable to an emerging disease. (22299428)
2011
25
Human ocular angiostrongyliasis: a literature review. (21296846)
2011
26
Comparison of major immunoglobulins intrathecal synthesis patterns in Ecuadorian and Cuban patients with angiostrongyliasis. (21363978)
2011
27
Development of a double antibody sandwich ELISA assay for the diagnosis of angiostrongyliasis. (21506824)
2011
28
Enzootic angiostrongyliasis, Guangdong, China, 2008-2009. (21762614)
2011
29
Abdominal angiostrongyliasis with involvement of liver histopathologically confirmed: a case report. (21915466)
2011
30
Treatment of angiostrongyliasis using a combination of albendazole and dexamethasone: the results of a retrospective and comparative study. (21294950)
2011
31
Outcomes in mice with abdominal angiostrongyliasis treated with enoxaparin. (21400113)
2011
32
An indirect immunofluorescence antibody test employing whole eggs as the antigen for the diagnosis of abdominal angiostrongyliasis. (21739024)
2011
33
International symposium on Angiostrongylus and Angiostrongyliasis, 2010. (21762566)
2011
34
Endemic angiostrongyliasis, Rio de Janeiro, Brazil. (21762612)
2011
35
Abdominal angiostrongyliasis caused by Angiostrongylus cantonensis: a possible cause of eosinophilic infiltration in human digestive tract. (19545957)
2010
36
Cerebrospinal fluid u-plasminogen activator and matrix metalloproteinase-9 levels in human eosinophilic meningitis associated with angiostrongyliasis. (20584616)
2010
37
Use of heterologous antigens for the immunodiagnosis of abdominal angiostrongyliasis by an enzyme-linked immunosorbent assay. (21120363)
2010
38
Peripheral eosinophilia as an indicator of meningitic angiostrongyliasis in exposed individuals. (21120370)
2010
39
Application of recombinant SMR-domain containing protein of angiostrongylus cantonensis in immunoblot diagnosis of human angiostrongyliasis. (21073053)
2010
40
Identification of factors associated with clinically severe angiostrongyliasis. (21118948)
2010
41
Immunological diagnosis of human angiostrongyliasis due to Angiostrongylus cantonensis (Nematoda: Angiostrongylidae). (19117782)
2009
42
Abdominal angiostrongyliasis: what does the rheumatologist must know about it? (20374358)
2009
43
Colon mass secondary to angiostrongyliasis. (19345351)
2009
44
Angiostrongyliasis in the Americas. (19523320)
2009
45
Thai koi-hoi snail dish and angiostrongyliasis due to Angiostrongylus cantonensis: Effects of food flavoring and alcoholic drink on the third-stage larvae in infected snail meat. (19272010)
2009
46
Human angiostrongyliasis outbreak in Dali, China. (19771154)
2009
47
Ocular angiostrongyliasis--first case report from Jamaica. (20099782)
2009
48
Cerebrospinal fluid cytokine responses in human eosinophilic meningitis associated with angiostrongyliasis. (17928005)
2008
49
Enzootic angiostrongyliasis in Shenzhen, China. (19046534)
2008
50
Angiostrongylus costaricensis egg antigen for the immunodiagnosis of abdominal angiostrongyliasis. (18462556)
2008

Variations for Angiostrongyliasis

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Expression for genes affiliated with Angiostrongyliasis

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Search GEO for disease gene expression data for Angiostrongyliasis.

Pathways for genes affiliated with Angiostrongyliasis

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Pathways related to Angiostrongyliasis according to GeneCards Suite gene sharing:

(show all 30)
idSuper pathwaysScoreTop Affiliating Genes
19.6MMP9, PLAU
2
Show member pathways
9.6MMP9, PLAU
39.6MMP9, PLAU
49.6MMP9, PLAU
59.6MMP9, PLAU
69.6MMP9, PLAU
79.4IL13, IL2
8
Show member pathways
8.8IL13, IL2, IL5
9
Show member pathways
8.8IL13, IL2, IL5
108.8IL2, IL4, MMP9
118.6CCL11, IL4, IL5
128.5IL13, IL4, IL5
13
Show member pathways
8.5IL13, IL4, IL5
14
Show member pathways
8.5IL2, IL4, IL5
158.5IL2, IL4, IL5
16
Show member pathways
8.5IL2, IL4, IL5
178.5IL2, IL4, IL5
188.0IL13, IL2, IL4, IL5
198.0IL13, IL2, IL4, IL5
208.0IL13, IL2, IL4, IL5
218.0IL13, IL2, IL4, IL5
22
Show member pathways
8.0IL13, IL2, IL4, IL5
237.6CCL11, IL13, IL2, IL4, IL5
24
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5
25
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5
26
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5
27
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5
28
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5
29
Show member pathways
7.6CCL11, IL13, IL2, IL4, IL5
307.6CCL11, IL13, IL2, IL4, IL5

GO Terms for genes affiliated with Angiostrongyliasis

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Cellular components related to Angiostrongyliasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055768.3CCL11, IL13, IL2, IL5, MMP9, PLAU
2extracellular spaceGO:00056156.7CCL11, IL13, IL2, IL4, IL5, MMP9

Biological processes related to Angiostrongyliasis according to GeneCards Suite gene sharing:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1embryo implantationGO:000756610.4MMP9, PLAU
2positive regulation of immunoglobulin secretionGO:005102410.0IL2, IL5
3extrinsic apoptotic signaling pathway in absence of ligandGO:00971929.9IL2, IL4
4microglial cell activationGO:00017749.8IL13, IL4
5negative regulation of complement-dependent cytotoxicityGO:19036609.8IL13, IL4
6negative regulation of endothelial cell apoptotic processGO:20003529.8IL13, IL4
7positive regulation of activated T cell proliferationGO:00421049.8IL2, IL4
8positive regulation of immunoglobulin productionGO:00026399.8IL13, IL4
9positive regulation of isotype switching to IgG isotypesGO:00483049.8IL2, IL4
10positive regulation of mast cell degranulationGO:00433069.8IL13, IL4
11positive regulation of T cell differentiationGO:00455829.7IL2, IL4
12positive regulation of tyrosine phosphorylation of Stat5 proteinGO:00425239.7IL2, IL4
13regulation of proton transportGO:00101559.7IL13, IL4
14inflammatory responseGO:00069549.6CCL11, IL13, IL5
15chemotaxisGO:00069359.5CCL11, IL4, PLAU
16positive regulation of protein phosphorylationGO:00019349.3IL2, IL4, MMP9
17immune responseGO:00069558.7IL13, IL2, IL4, IL5
18positive regulation of cell proliferationGO:00082848.7IL2, IL4, IL5, PLAU
19positive regulation of B cell proliferationGO:00308908.7IL13, IL2, IL4, IL5
20response to ethanolGO:00454718.6IL13, IL2, IL4

Molecular functions related to Angiostrongyliasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:00051258.6IL13, IL2, IL4, IL5
2growth factor activityGO:00080838.5IL2, IL4, IL5

Sources for Angiostrongyliasis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet