MCID: ANH002
MIFTS: 54

Anhidrosis malady

Skin diseases category
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Summaries for Anhidrosis

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65Wikipedia, 47OMIM, 33MalaCards
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Wikipedia:65 Hypohidrosis is diminished sweating in response to appropriate stimuli. While hyperhidrosis is a... more...

MalaCards: Anhidrosis, also known as absence of sweating, is related to hypohidrosis and autonomic neuropathy. An important gene associated with Anhidrosis is NTRK1 (neurotrophic tyrosine kinase, receptor, type 1), and among its related pathways are Activation of TRKA receptors and Apoptosis and survival Anti apoptotic TNFs NF kB Bcl 2 pathway. The compounds cipa and mipafox have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and bone, and related mouse phenotypes are vision/eye and no phenotypic analysis.

Description from OMIM:47 206600

Aliases & Classifications for Anhidrosis

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8Disease Ontology, 10DISEASES, 45Novoseek, 62UMLS, 47OMIM, 58SNOMED-CT, 40NCIt, 35MeSH, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases


Aliases & Descriptions:

anhidrosis 8 10 45 62
absence of sweating 8
adiaphoresis 8


External Ids:

Disease Ontology8 DOID:11156
OMIM47 206600
NCIt40 C34385
MeSH35 D007007
ICD9CM27 705.0
ICD1025 L74.4

Related Diseases for Anhidrosis

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17GeneCards, 18GeneDecks
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Diseases related to Anhidrosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 118)
idRelated DiseaseScoreTop Affiliating Genes
1hypohidrosis30.6GLA
2autonomic neuropathy30.5NTRK1, NGF
3hereditary sensory neuropathy30.2NGF, NTRK1
4pyruvate kinase deficiency30.0PKLR
5multiple sclerosis29.8NGF, NGFR, MAPK10
6congenital insensitivity to pain with anhidrosis10.9
7neuropathy10.6
8alopecia10.3
9miliaria10.3
10horner's syndrome10.2
11dermatitis10.1
12ectodermal dysplasia10.1
13harlequin syndrome10.1
14neuroaxonal dystrophy10.1NGF, NTRK1
15rett syndrome10.1NGF, NTRK1
16sensory peripheral neuropathy10.1NGF, NTRK1
17polyneuropathy10.1ACHE
18thymus cancer10.1NTRK1, NGFR
19gaucher's disease10.1GLA, PKLR
20sialadenitis10.1
21cholinergic urticaria10.1
22impotence10.1
23leprosy10.1
24urticaria10.1
25vasculitis10.1
26postural hypotension10.1
27papillary thyroid carcinoma10.0NTRK1, MAPK10
28memory impairment10.0ACHE, NGF
29diabetic neuropathy10.0NTRK1, NGFR, NGF
30ganglioneuroma10.0NGF, NGFR, NTRK1
31prion disease10.0ACHE, NTRK1, NGF
32neuroblastoma10.0NTRK1, NGFR, NGF
33cholera10.0NGF, NTRK1, ACHE
34amyotrophic lateral sclerosis10.0NTRK1, NGFR, NGF
35prolactinoma10.0NGF, NGFR
36hirschsprung's disease10.0ACHE, NTRK1, NGFR
37myopathy10.0NGF, ACHE, PKLR
38huntington's disease10.0NGF, NGFR, ACHE
39cerebrovascular disease10.0GLA, MAPK10, NTRK1
40epilepsy syndrome10.0NGF, NGFR, ACHE
41thymoma10.0NTRK1, NGFR
42neurilemmoma10.0ACHE, NGFR
43dementia10.0MAPK10, ACHE, NGF
44polycystic kidney disease10.0MAPK10, MAPK1
45parkinson's disease10.0ACHE, NTRK1, NGFR, NGF
46thyroid cancer10.0NTRK1, MAPK10, MAPK1
47neuroepithelioma10.0NGF, MAPK10, MAPK1
48medulloblastoma10.0MAPK10, NTRK1, NGFR, NGF
49chronic myeloid leukemia10.0MAPK1, MAPK10, NTRK1
50schizophrenia10.0NGF, NTRK1, ACHE, MAPK10

Graphical network of the top 20 diseases related to Anhidrosis:



Diseases related to anhidrosis

Symptoms for Anhidrosis

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47OMIM
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Clinical features from OMIM:

206600

Drugs & Therapeutics for Anhidrosis

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Anhidrosis

Search NIH Clinical Center for Anhidrosis

Genetic Tests for Anhidrosis

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Anatomical Context for Anhidrosis

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33MalaCards
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MalaCards organs/tissues related to Anhidrosis:

33
Skin, Testes, Bone, Spinal cord, Lung, T cells

Animal Models for Anhidrosis or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Anhidrosis:

37 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.7ACHE, NTRK1, NGFR, NGF
2MP:00030128.4NGF, NTRK1, ACHE, MAPK10, ALOXE3
3MP:00107718.1NGF, NGFR, NTRK1, MAPK1, ALOXE3
4MP:00053697.8GLA, MAPK1, ACHE, NTRK1, NGFR, NGF
5MP:00053857.7NGF, NGFR, MAPK10, MAPK1, GLA
6MP:00053977.6NGFR, NTRK1, ACHE, PKLR, MAPK1
7MP:00053787.5NGF, NGFR, NTRK1, ACHE, MAPK1, ALOXE3
8MP:00036317.4NGF, NGFR, NTRK1, ACHE, MAPK10, MAPK1
9MP:00107687.2NGF, NGFR, NTRK1, ACHE, PKLR, MAPK1
10MP:00053867.2NGF, NGFR, NTRK1, ACHE, MAPK10, MAPK1
11MP:00053766.9NGF, NGFR, ACHE, PKLR, MAPK10, MAPK1

Publications for Anhidrosis

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52PubMed
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Articles related to Anhidrosis:

(show top 50)    (show all 243)
idTitleAuthorsYear
1
Old fractures in two patients with congenital insensitivity to pain with anhidrosis: radiological findings. (23478071)
2013
2
Acquired generalized anhidrosis: review of the literature and report of a case with lymphocytic hidradenitis and sialadenitis successfully treated with cyclosporine. (24191980)
2013
3
Nerve growth factor and the physiology ofA pain: lessons from congenital insensitivity to pain with anhidrosis. (22882139)
2012
4
Unilateral anhidrosis: a rare presentation of atrial myxoma? (23230264)
2012
5
Novel nonsense and frameshift NTRK1 gene mutations in Chinese patients with congenital insensitivity to pain with anhidrosis. (22653642)
2012
6
Right ptosis, anhidrosis, and miosis developed in a 49-year-old man with chronic dry cough for 2 months. (22796847)
2012
7
Anhidrosis after anterior retroperitoneal approach for L4-L5 artificial disc replacement. (21570302)
2011
8
A short in-frame deletion in NTRK1 tyrosine kinase domain caused by a novel splice site mutation in a patient with congenital insensitivity to pain with anhidrosis. (21708027)
2011
9
Evaluation of nonnociceptive sensation in patients with congenital insensitivity to pain with anhidrosis. (20013280)
2010
10
Nerve growth factor, pain, itch and inflammation: lessons from congenital insensitivity to pain with anhidrosis. (20977328)
2010
11
Clinical and genetic analysis of Korean patients with congenital insensitivity to pain with anhidrosis. (19618435)
2009
12
Nerve growth factor, interoception, and sympathetic neuron: lesson from congenital insensitivity to pain with anhidrosis. (19201660)
2009
13
Isolated generalised anhidrosis induced by postganglionic sympathetic skin nerve fibre degeneration: an incomplete Ross syndrome? (18356251)
2008
14
Novel missense, insertion and deletion mutations in the neurotrophic tyrosine kinase receptor type 1 gene (NTRK1) associated with congenital insensitivity to pain with anhidrosis. (18077166)
2008
15
Idiopathic generalized anhidrosis: a feature of panautonomic failure. (18797081)
2008
16
Congenital insensitivity to pain with anhidrosis and progressing acro-osteolysis: a case report with 7-year follow-up. (17199968)
2006
17
Clinical and genetic aspects of congenital insensitivity to pain with anhidrosis]. (15999564)
2005
18
A novel lymphocyte signaling defect: trk A mutation in the syndrome of congenital insensitivity to pain and anhidrosis (CIPA). (15163901)
2004
19
Idiopathic pure sudomotor failure: anhidrosis due to deficits in cholinergic transmission. (15505168)
2004
20
Intrasinus wood foreign body causing orbital cellulitis in congenital insensitivity to pain with anhidrosis syndrome. (14752319)
2004
21
Congenital insensitivity of pain with anhidrosis. (12619965)
2003
22
Post-herpetic neuralgia in a patient with congenital insensitivity to pain and anhidrosis. (14566502)
2002
23
Genetics of congenital insensitivity to pain with anhidrosis (CIPA) or hereditary sensory and autonomic neuropathy type IV. Clinical, biological and molecular aspects of mutations in TRKA(NTRK1) gene encoding the receptor tyrosine kinase for nerve growth factor. (12102460)
2002
24
Indolent corneal ulcers in a patient with congenital insensitivity to pain with anhidrosis: a case report and literature review. (11936447)
2002
25
Congenital insensitivity to pain with anhidrosis (CIPA): the spectrum of radiological findings. (11685437)
2001
26
Congenital insensitivity to pain with anhidrosis: an NGF/TrkA-related disorder. (11241480)
2001
27
Two novel mutant alleles of the gene encoding neurotrophic tyrosine kinase receptor type 1 (NTRK1) in a patient with congenital insensitivity to pain with anhidrosis: a splice junction mutation in intron 5 and cluster of four mutations in exon 15. (11139246)
2001
28
Neurophysiologic studies in congenital insensitivity to pain with anhidrosis. (11744315)
2001
29
Congenital insensitivity to pain with anhidrosis. (11483399)
2001
30
Congenital insensitivity to pain with anhidrosis (CIPA) in Israeli- Bedouins: genetic heterogeneity, novel mutations in the TRKA/NGF receptor gene, clinical findings, and results of nerve conduction studies. (10861667)
2000
31
The Gly571Arg mutation, associated with the autonomic and sensory disorder congenital insensitivity to pain with anhidrosis, causes the inactivation of the NTRK1/nerve growth factor receptor. (10567924)
2000
32
Complete paternal uniparental isodisomy for chromosome 1 revealed by mutation analyses of the TRKA (NTRK1) gene encoding a receptor tyrosine kinase for nerve growth factor in a patient with congenital insensitivity to pain with anhidrosis. (11071380)
2000
33
Congenital insensitivity to pain with anhidrosis. Report of a case and review of the literature. (10842874)
2000
34
Congenital insensitivity to pain with anhidrosis: ocular and systemic manifestations. (10088743)
1999
35
Traumatic Horner syndrome without anhidrosis. (10380140)
1999
36
Unilateral loss of facial flushing and sweating with contralateral anhidrosis: harlequin syndrome or Adie's syndrome? (8292878)
1993
37
Axonal degeneration of the peripheral nerves and postganglionic anhidrosis in a patient with multiple sclerosis. (1965353)
1990
38
Familial generalized anhidrosis. (2401613)
1990
39
Idiopathic acquired generalized anhidrosis: electron-microscopic and immunohistochemical studies and analysis of lectin-binding pattern of the cell membrane. (2721803)
1989
40
Clinical, clinicopathologic, and epidemiologic features of anhidrosis in central Florida Thoroughbred horses. (3506097)
1987
41
Equine anhidrosis: a survey of affected horses in Florida. (7068500)
1982
42
Studies on the mechanism of topical anhidrosis due to polyvalent cations. (19469924)
1981
43
The role of bacteria in anhidrosis. (4750804)
1973
44
Miliaria and anhidrosis. 3. Multiple small patches and the effects of different periods of occlusion. (5030233)
1972
45
Pruritus and acquired anhidrosis. Two unusual cases. (5822371)
1969
46
Congenital sensory neuropathy with anhidrosis. (4171106)
1968
47
Miliaria and anhidrosis. I. Experimental production in volunteers. (6062874)
1967
48
The significance of temporary and alternating ptosis, miosis and anhidrosis. (13272050)
1955
49
A form of ectodermal dysplasia; hypotrichosis with anhidrosis and anodontia]. (13023176)
1952
50
Tropical anidrotic asthenia (thermogenic anhidrosis) and its relationship to prickly heat. (20244419)
1946

Variations for Anhidrosis

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Expression for genes affiliated with Anhidrosis

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Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Anhidrosis

Search GEO for disease gene expression data for Anhidrosis.

Pathways for genes affiliated with Anhidrosis

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Sources:
50PathCards, 55Reactome, 60Thomson Reuters, 53QIAGEN, 30KEGG, 5Cell Signaling Technology, 38NCBI BioSystems Database, 57SinoBiological, 51PharmGKB, 61Tocris Bioscience, 54R&D Systems
See all sources

Pathways related to Anhidrosis according to GeneCards/GeneDecks:

(show top 50)    (show all 51)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.8NTRK1, NGF
2
Show member pathways
Apoptosis and survival Anti apoptotic TNFs NF kB IAP pathway60
9.6NGFR, NGF
39.3NTRK1, MAPK1
49.3MAPK1, NTRK1
59.3NTRK1, NGFR, NGF
69.1MAPK1, ACHE
7
Show member pathways
9.0MAPK10, MAPK1
8
Show member pathways
TRAIL signaling pathway38
9.0MAPK1, MAPK10
99.0MAPK10, MAPK1
10
Show member pathways
9.0MAPK1, MAPK10
119.0MAPK1, MAPK10
129.0MAPK1, MAPK10
13
Show member pathways
Cell cycle ESR1 regulation of G1 S transition60
Immune response MIF JAB1 signaling60
Cell cycle Cell cycle generic schema 60
9.0MAPK1, MAPK10
149.0MAPK10, MAPK1
15
Show member pathways
9.0MAPK10, MAPK1
16
Show member pathways
Apoptosis and survival Lymphotoxin beta receptor signaling60
9.0MAPK1, MAPK10
17
Show member pathways
9.0NGFR, NTRK1, MAPK10
18
Show member pathways
9.0MAPK1, NTRK1, NGF
19
Show member pathways
9.0NGF, NGFR, MAPK10
20
Show member pathways
9.0NGF, NTRK1, MAPK1
21
Show member pathways
9.0NGF, NTRK1, MAPK1
22
Show member pathways
8.8MAPK1, NTRK1, NGFR
238.8NTRK1, ACHE, MAPK1
248.8NGF, NGFR, MAPK1
25
Show member pathways
8.7MAPK1, MAPK10, NTRK1
268.7MAPK1, MAPK10, NTRK1
27
Show member pathways
8.6MAPK1, MAPK10, PKLR
28
Show member pathways
Transcription Receptor mediated HIF regulation60
Development CNTF receptor signaling60
Class IB PI3K non-lipid kinase events38
ErbB2/ErbB3 signaling events38
Development Growth hormone signaling via PI3K AKT and MAPK cascades60
Translation Regulation activity of EIF260
Regulation of lipid metabolism Insulin signaling generic cascades60
Transcription PPAR Pathway60
Cell adhesion PLAU signaling60
Translation Regulation activity of EIF4F60
8.6MAPK1, MAPK10, PKLR
29
Show member pathways
Apoptosis and survival TNFR1 signaling pathway60
TWEAK Signaling Pathway38
Apoptosis Modulation by HSP7038
HIV-1 Nef- Negative effector of Fas and TNF-alpha38
8.5MAPK1, MAPK10, NGFR
30
Show member pathways
8.5NGFR, MAPK10, MAPK1
31
Show member pathways
8.5ACHE, MAPK10, MAPK1
32
Show member pathways
Cytoskeleton remodeling Fibronectin binding integrins in cell motility60
Cytoskeleton remodeling Integrin outside in signaling60
Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases60
Cell adhesion Tight junctions60
Development MAG dependent inhibition of neurite outgrowth60
8.4MAPK1, NTRK1, NGFR, NGF
33
Show member pathways
8.4MAPK1, NTRK1, NGFR, NGF
34
Show member pathways
8.4NGF, NGFR, NTRK1, MAPK1
35
Show member pathways
Cytoskeleton remodeling FAK signaling60
Development Endothelin 1 EDNRA transactivation of EGFR60
8.3MAPK1, MAPK10, NTRK1, NGF
36
Show member pathways
8.3NGF, NTRK1, MAPK10, MAPK1
37
Show member pathways
8.3NGF, NTRK1, MAPK10, MAPK1
38
Show member pathways
MAPK signaling pathway38
8.3NGF, NTRK1, MAPK10, MAPK1
39
Show member pathways
8.2NGFR, NTRK1, MAPK10, MAPK1
40
Show member pathways
8.2MAPK1, MAPK10, NTRK1, NGFR
41
Show member pathways
8.2NGFR, NTRK1, MAPK10, MAPK1
42
Show member pathways
8.2MAPK1, MAPK10, NTRK1, NGFR
43
Show member pathways
8.2NGFR, NTRK1, MAPK10, MAPK1
44
Show member pathways
8.2MAPK1, MAPK10, NTRK1, NGFR
45
Show member pathways
8.2NGFR, NTRK1, MAPK10, MAPK1
46
Show member pathways
8.2MAPK1, MAPK10, NTRK1, NGFR
47
Show member pathways
8.1MAPK1, MAPK10, NGFR, NGF
48
Show member pathways
8.1NGF, NGFR, MAPK10, MAPK1
49
Show member pathways
Development EGFR signaling via PIP360
Development PDGF signaling via MAPK cascades60
Apoptosis and survival Anti apoptotic action of membrane bound ESR160
Signaling of Hepatocyte Growth Factor Receptor38
Development EGFR signaling via small GTPases60
Development Neurotrophin family signaling60
Apoptosis and survival NGF signaling pathway60
Apoptosis and survival Role of CDK5 in neuronal death and survival60
7.8NGF, NGFR, NTRK1, MAPK10, MAPK1
507.8MAPK1, MAPK10, NTRK1, NGFR, NGF

Compounds for genes affiliated with Anhidrosis

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Sources:
45Novoseek, 61Tocris Bioscience, 11DrugBank, 24HMDB, 29IUPHAR, 51PharmGKB, 3BitterDB
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Compounds related to Anhidrosis according to GeneCards/GeneDecks:

(show top 50)    (show all 97)
idCompoundScoreTop Affiliating Genes
1cipa4510.1NTRK1, NGF
2mipafox459.9ACHE, NGF
3estradiol valerate459.9NGFR, NGF
4propentofylline459.8NTRK1, NGF
5ana 12619.7NGF, NGFR, NTRK1
6tlqp 21619.7NGF, NGFR, NTRK1
7bdnf (human)619.7NGF, NTRK1, NGFR
8gnf 5837619.7NTRK1, NGFR, NGF
97,8-dihydroxyflavone61 4510.7NTRK1, NGFR, NGF
10ag 879459.6NGF, NTRK1, MAPK10
111,4-diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene459.4MAPK10, MAPK1
12pyridinylimidazole459.4MAPK10, MAPK1
13gw-5074459.4MAPK10, MAPK1
14rasagiline45 1110.4MAPK10, ACHE, NGF
15ganglioside459.3GLA, NTRK1, NGFR, NGF
16kn 93459.2MAPK1, MAPK10
17choline45 24 1111.1NGF, NGFR, NTRK1, ACHE
18farnesylthiosalicylic acid29 4510.1MAPK1, MAPK10
19olomoucine45 1110.0MAPK1, MAPK10, NGF
20pdtc458.9NGF, MAPK10, MAPK1
21anisomycin45 119.9NGF, MAPK10, MAPK1
22dopamine45 29 24 1111.9NGF, NGFR, NTRK1, ACHE
23nicotine45 29 51 1111.8MAPK10, ACHE, NGFR, NGF
24matrigel458.8NGF, NGFR, NTRK1, MAPK1
25c2ceramide458.8MAPK1, MAPK10, NTRK1, NGF
26arachidonic acid45 29 24 1111.8NGFR, NTRK1, MAPK10, ALOXE3
27pd 98,059458.7NGF, NTRK1, MAPK10, MAPK1
28ly294002458.6NGF, NTRK1, MAPK10, MAPK1
29phorbol458.6NGFR, NTRK1, MAPK10, MAPK1
30genistein45 29 61 3 24 1113.6MAPK1, MAPK10, NTRK1, NGF
31gf 109203x45 619.6NGF, MAPK10, MAPK1
32acetylcholine45 51 29 24 1112.5NGF, NGFR, NTRK1, ACHE, MAPK10
33forskolin45 51 1110.4MAPK1, MAPK10, NGFR, NGF
34adenylate458.3MAPK1, MAPK10, NTRK1, NGF
35k252a458.3MAPK1, MAPK10, NTRK1, NGFR, NGF
36thymidine45 249.2NGF, NGFR, MAPK10, MAPK1
37phosphotyrosine458.2NGF, NGFR, NTRK1, MAPK10, MAPK1
3812-o-tetradecanoylphorbol 13-acetate458.2NGF, NGFR, NTRK1, MAPK10, MAPK1
39wortmannin458.2NGF, NGFR, NTRK1, MAPK10, MAPK1
40phosphoinositide458.2NGF, NGFR, NTRK1, MAPK10, MAPK1
41vegf458.2NGF, NGFR, NTRK1, MAPK10, MAPK1
42phosphatidylinositol458.2NGF, NGFR, NTRK1, MAPK10, MAPK1
43retinoic acid45 249.1NGF, NGFR, NTRK1, MAPK10, MAPK1
44nmda45 299.0NGF, NGFR, ACHE, MAPK10, MAPK1
45glutamate458.0NGF, NGFR, NTRK1, ACHE, MAPK1, GLA
46ceramide457.9NGF, NGFR, NTRK1, MAPK10, MAPK1, GLA
47threonine457.9NGF, NGFR, NTRK1, MAPK10, MAPK1, GLA
48tyrosine457.7NGF, NGFR, NTRK1, PKLR, MAPK10, MAPK1
49calcium45 51 24 1110.2NGF, NGFR, NTRK1, MAPK10, MAPK1, GLA
50serine457.0NGF, NGFR, NTRK1, ACHE, PKLR, MAPK10

GO Terms for genes affiliated with Anhidrosis

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16Gene Ontology
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Cellular components related to Anhidrosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell surfaceGO:0099869.1ACHE, NTRK1, NGFR
2endosomeGO:0057689.0NTRK1, NGFR, NGF

Biological processes related to Anhidrosis according to GeneCards/GeneDecks:

(show all 21)
idNameGO IDScoreTop Affiliating Genes
1response to electrical stimulusGO:05160210.1NGF, NTRK1
2response to radiationGO:00931410.1NTRK1, NGF
3activation of phospholipase C activityGO:0072029.9NTRK1, NGF
4regulation of cysteine-type endopeptidase activity involved in apoptotic processGO:0432819.9NGFR, NGF
5positive regulation of axonogenesisGO:0507729.9NGFR, NGF
6transmembrane receptor protein tyrosine kinase signaling pathwayGO:0071699.8NTRK1, NGF
7extrinsic apoptotic signaling pathway via death domain receptorsGO:0086259.8NGF, NGFR
8negative regulation of cell cycleGO:0457869.8NGFR, NGF
9regulation of axonogenesisGO:0507709.4ACHE, NGFR, NGF
10activation of MAPKK activityGO:0001869.3MAPK1, NTRK1, NGF
11Ras protein signal transductionGO:0072659.3MAPK1, NTRK1, NGF
12regulation of sequence-specific DNA binding transcription factor activityGO:0510909.2MAPK10, MAPK1
13stress-activated MAPK cascadeGO:0514039.2MAPK10, MAPK1
14small GTPase mediated signal transductionGO:0072649.2MAPK1, NTRK1, NGF
15sensory perception of painGO:0192339.2NGF, MAPK1, ALOXE3
16toll-like receptor 10 signaling pathwayGO:0341669.0MAPK10, MAPK1
17toll-like receptor TLR6:TLR2 signaling pathwayGO:0381249.0MAPK1, MAPK10
18axon guidanceGO:0074119.0MAPK1, NTRK1, NGFR
19toll-like receptor 5 signaling pathwayGO:0341468.9MAPK10, MAPK1
20neurotrophin TRK receptor signaling pathwayGO:0480118.8NGF, NGFR, NTRK1, MAPK1
21toll-like receptor TLR1:TLR2 signaling pathwayGO:0381238.7MAPK1, MAPK10

Molecular functions related to Anhidrosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nerve growth factor bindingGO:0484069.3NTRK1, NGFR
2protein bindingGO:0055156.9GLA, ALOXE3, MAPK1, MAPK10, ACHE, NTRK1

Products for genes affiliated with Anhidrosis

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  • Antibodies
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Sources for Anhidrosis

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet