Aliases & Classifications for Anhidrosis

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Aliases & Descriptions for Anhidrosis:

Name: Anhidrosis 10 47 12 65
Absence of Sweating 10
 
Adiaphoresis 10

Classifications:



External Ids:

Disease Ontology10 DOID:11156
ICD1027 L74.4
ICD9CM29 705.0
MeSH36 D007007
NCIt42 C34385
UMLS65 C0003028

Summaries for Anhidrosis

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Wikipedia:68 Hypohidrosis is diminished sweating in response to appropriate stimuli. While hyperhidrosis is a... more...

MalaCards based summary: Anhidrosis, also known as absence of sweating, is related to insensitivity to pain, congenital, with anhidrosis and anhidrosis, isolated, with normal sweat glands. An important gene associated with Anhidrosis is NTRK1 (Neurotrophic Receptor Tyrosine Kinase 1), and among its related pathways are Activation of TRKA receptors and 14-3-3 and Regulation of BAD Activity. Affiliated tissues include skin, lung and liver, and related mouse phenotypes are integument and vision/eye.

Related Diseases for Anhidrosis

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Diseases related to Anhidrosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 207)
idRelated DiseaseScoreTop Affiliating Genes
1insensitivity to pain, congenital, with anhidrosis12.7
2anhidrosis, isolated, with normal sweat glands12.5
3harlequin syndrome11.5
4van den bosch syndrome11.3
5hypohidrosis10.9
6horner's syndrome10.3
7neuropathy, hereditary sensory and autonomic, type v10.3NGF, NTRK1
8oral cavity carcinoma in situ10.3NGF, NTRK1
9asthma10.2
10arthritis10.2
11hepatitis10.2
12thrombotic thrombocytopenic purpura, familial10.2NGF, NTRK1
13ectodermal dysplasia 11b, hypohidrotic/hair/tooth type, autosomal recessive10.2
14ectodermal dysplasia 11a, hypohidrotic/hair/tooth type, autosomal dominant10.2
15ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant10.2
16ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive10.2
17ichthyosis, congenital, autosomal recessive 4a10.2
18ichthyosis, congenital, autosomal recessive 610.2
19ichthyosis, congenital, autosomal recessive 1010.2
20ichthyosis, congenital, autosomal recessive 810.2
21ichthyosis, congenital, autosomal recessive 1110.2
22ichthyosis, congenital, autosomal recessive 710.2
23immunodeficiency 910.2
24ichthyosis, congenital, autosomal recessive 110.2
25ichthyosis, congenital, autosomal recessive 910.2
26ichthyosis, congenital, autosomal recessive 210.2
27ichthyosis, congenital, autosomal recessive 310.2
28ichthyosis, congenital, autosomal recessive 510.2
29ectodermal dysplasia 1, hypohidrotic, x-linked10.2
30breast cancer10.2
31leukemia10.2
32lymphoma10.2
33prostatitis10.2
34glioblastoma10.2
35endotheliitis10.2
36patent ductus arteriosus10.2GLA, NTRK1
37pyruvate kinase deficiency10.1NTRK1, PKLR
38jmp syndrome10.1NGF, NTRK1
39pruritic urticarial papules plaques of pregnancy10.1NGF, NGFR
40brachial plexus neuropathy10.1NGFR, NTRK1
41schizophrenia10.1
42neuroblastoma10.1
43obesity10.1
44aplastic anemia10.1
45psoriatic arthritis10.1
46acne10.1
47chronic lymphocytic leukemia10.1
48sarcoma10.1
49disseminated intravascular coagulation10.1
50mesenchymoma10.1

Graphical network of the top 20 diseases related to Anhidrosis:



Diseases related to anhidrosis

Symptoms for Anhidrosis

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Drugs & Therapeutics for Anhidrosis

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Interventional clinical trials:

idNameStatusNCT IDPhase
1A Study of Norepinephrine in Patients With Congenital Insensitivity to Pain and AnhidrosisWithdrawnNCT02624310Phase 2

Search NIH Clinical Center for Anhidrosis

Genetic Tests for Anhidrosis

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Anatomical Context for Anhidrosis

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MalaCards organs/tissues related to Anhidrosis:

33
Skin, Lung, Liver, Breast, Colon, Bone, Endothelial

Animal Models for Anhidrosis or affiliated genes

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MGI Mouse Phenotypes related to Anhidrosis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.4IKBKG, ITPR2, NGF, NGFR, NTRK1, ORAI1
2MP:00053918.3GLA, NGF, NGFR, NTRK1, ORAI1
3MP:00028738.3IKBKG, ITPR2, NGF, NGFR, NTRK1, PKLR
4MP:00053877.3GLA, IKBKG, NGFR, NTRK1, ORAI1, PKLR
5MP:00053766.9GLA, IKBKG, ITPR2, NGF, NGFR, ORAI1
6MP:00053786.9GLA, IKBKG, ITPR2, NGF, NGFR, NTRK1
7MP:00107686.5GLA, IKBKG, ITPR2, NGF, NGFR, NTRK1

Publications for Anhidrosis

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Articles related to Anhidrosis:

(show top 50)    (show all 273)
idTitleAuthorsYear
1
Assessing Metabolic Changes in Response to mTOR Inhibition in a Mantle Cell Lymphoma Xenograft Model Using AcidoCEST MRI. (27140422)
2016
2
Clival Syndrome Secondary to Anaerobic Mastoiditis in A 2-Year-Old Child. (26164849)
2015
3
Reply: Serum microRNA screening for DICER1-associated pleuropulmonary blastoma. (25251372)
2014
4
Adiponectin exerts antiproliferative effect on human placenta via modulation of the JNK/c-Jun pathway. (25031708)
2014
5
Fabry disease. (25345090)
2014
6
Atypical teratoid/rhabdoid tumor in sellar turcica in an adult: A case report and review of the literature. (24949218)
2014
7
Good cognitive performances in a child with Prader-Willi syndrome. (24238393)
2013
8
Current trends in leprosy transmission in eastern India in the era of 12-month multi-drug treatment: a hospital-based retrospective study. (23968315)
2013
9
Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork. (23390603)
2013
10
Portal vein thrombosis and budd-Chiari syndrome. (22054734)
2011
11
Male infertility: pathogenesis and clinical diagnosis. (21397198)
2011
12
Yellow fever in Africa and Central and South America, 2008a892009. (21268439)
2011
13
Oxytocin immunoreactivity in the corpus cavernosum of patients with erectile dysfunction. (21832819)
2011
14
Relationships between levels of serum IgE, cell-bound IgE, and IgE-receptors on peripheral blood cells in a pediatric population. (20808937)
2010
15
Hyperglycemia during induction therapy is associated with poorer survival in children with acute lymphocytic leukemia. (19394046)
2009
16
Ezrin overexpression in gastrointestinal stromal tumors: an independent adverse prognosticator associated with the non-gastric location. (19648886)
2009
17
Cartilage oligomeric matrix protein/thrombospondin-5 (COMP/TSP-5) levels do not correlate to functional class in patients with rheumatoid arthritis. (19727918)
2009
18
Clinical evaluation of polyamide polymer burs for selective carious dentin removal. (19575051)
2009
19
Treatment of postpartum depression with psychotic features in a patient with tropical spastic paraparesis. (18413682)
2008
20
Arrhythmogenic right ventricular dysplasia/cardiomyopathy: clinical profile of four patients and review. (18364664)
2008
21
Vardenafil restores erectile function to normal range in men with erectile dysfunction. (17233781)
2007
22
Laminar fate of cortical GABAergic interneurons is dependent on both birthdate and phenotype. (17245711)
2007
23
Molecular assay of -alpha(3.7) and -alpha(4.2) deletions causing alpha-thalassemia by denaturing high-performance liquid chromatography. (17512924)
2007
24
Potential role of trans-inhibition of the bile salt export pump by progesterone metabolites in the etiopathogenesis of intrahepatic cholestasis of pregnancy. (16458994)
2006
25
Glycyrrhetinic acid and related compounds induce G1 arrest and apoptosis in human hepatocellular carcinoma HepG2. (16309197)
2005
26
Eosinophil cationic protein in human milk is associated with development of cow's milk allergy and atopic eczema in breast-fed infants. (14630983)
2004
27
Distinct RE-1 silencing transcription factor-containing complexes interact with different target genes. (14561745)
2004
28
Chromosome aneuploidy in the spermatozoa of two men with globozoospermia. (15448169)
2004
29
Ligands of peroxisome proliferator-activated receptor gamma inhibit lung cancer cell growth and induce apoptosis by stimulation of P21 expression. (15136464)
2004
30
The antibiotic polymyxin B modulates P2X7 receptor function. (15383600)
2004
31
Introduction of wild-type p53 enhances thrombospondin-1 expression in human glioma cells. (12609716)
2003
32
Evaluating the medical literature in reproductive medicine: questions concerning prognosis. (12806557)
2003
33
Pulmonary AL amyloidosis in a patient with primary SjAPgren syndrome. (24383839)
2002
34
Multicenter, dose-ranging study of efegatran sulfate versus heparin with thrombolysis for acute myocardial infarction: The Promotion of Reperfusion in Myocardial Infarction Evolution (PRIME) trial. (11773918)
2002
35
Intramedullary spinal cord germinoma: case report and review of the literature. (11997540)
2002
36
Gene expression profiling of human stent-induced neointima by cDNA array analysis of microscopic specimens retrieved by helix cutter atherectomy: Detection of FK506-binding protein 12 upregulation. (11245643)
2001
37
Expression and function of the mouse collagen receptor glycoprotein VI is strictly dependent on its association with the FcRgamma chain. (10825177)
2000
38
A C2077T polymorphism of the type B human natriuretic peptide receptor gene is not associated with myocardial infarction. (11208455)
2000
39
Neurotrophic factors modulate hair cells and their potassium currents in chick otocyst explants. (10051769)
1999
40
A novel function of Stat1 and Stat3 proteins in erythropoietin-induced erythroid differentiation of a human leukemia cell line. (9657745)
1998
41
Extracellular matrix proteins induce changes in intracellular calcium and cyclic AMP signalling systems in cultured human keratinocytes. (9177878)
1997
42
Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating kappaB enhancer activation. (8621542)
1996
43
CGRP-induced activation of KATP channels in follicular Xenopus oocytes. (7530840)
1994
44
Human liver and human placenta both contain CMP-NeuAc:Gal beta 1-->4GlcNAc-R alpha 2-->3- as well as alpha 2-->6-sialyltransferase activity. (1426235)
1992
45
Deoxyribonucleic acid flow cytometric analysis of cervical adenocarcinoma: prognostic significance of deoxyribonucleic acid ploidy and S-phase fraction. (2316596)
1990
46
Coxsackievirus B3 producing fatal meningoencephalitis in a patient with X-linked agammaglobulinemia. (6293302)
1983
47
Hepatic involvement in the Bardet-Biedl syndrome. (7158637)
1982
48
Sex differences in chronic cor pulmonale in delhi. (990163)
1976
49
51Cr lung scan in idiopathic pulmonary hemosiderosis. (5784706)
1969
50
Cerebral thromboangiitis obliterans. (20289123)
1947

Variations for Anhidrosis

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Expression for genes affiliated with Anhidrosis

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Search GEO for disease gene expression data for Anhidrosis.

Pathways for genes affiliated with Anhidrosis

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Pathways related to Anhidrosis according to GeneCards Suite gene sharing:

(show all 16)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.8NGF, NTRK1
29.7NGF, NGFR
39.6ITPR2, ORAI1
49.5IKBKG, ORAI1
59.4NGF, NGFR, NTRK1
69.4NGF, NGFR, NTRK1
7
Show member pathways
9.4NGF, NGFR, NTRK1
8
Show member pathways
9.3IKBKG, NGFR, NTRK1
99.2IKBKG, NGF, NGFR
10
Show member pathways
9.2IKBKG, NGF, NGFR
11
Show member pathways
9.2IKBKG, NGF, NGFR
12
Show member pathways
9.2IKBKG, NGF, NGFR
13
Show member pathways
9.0ITPR2, NGF, NGFR, NTRK1
14
Show member pathways
9.0IKBKG, ITPR2, NGF, NTRK1
15
Show member pathways
8.9IKBKG, NGF, NGFR, NTRK1
16
Show member pathways
8.6IKBKG, ITPR2, NGF, NGFR, NTRK1

GO Terms for genes affiliated with Anhidrosis

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Biological processes related to Anhidrosis according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1regulation of cysteine-type endopeptidase activity involved in apoptotic processGO:004328110.1NGF, NGFR
2transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071699.9NGF, NTRK1
3negative regulation of cell cycleGO:00457869.8NGF, NGFR
4negative regulation of cysteine-type endopeptidase activity involved in apoptotic processGO:00431549.7NGF, NGFR
5sensory perception of painGO:00192339.6NGFR, NTRK1
6activation of phospholipase C activityGO:00072029.4ITPR2, NGF, NTRK1
7activation of cysteine-type endopeptidase activity involved in apoptotic processGO:00069199.4NGF, NGFR

Sources for Anhidrosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet