MCID: ANH002
MIFTS: 54

Anhidrosis malady

Skin diseases category

Summaries for Anhidrosis

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66Wikipedia, 48OMIM, 34MalaCards
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Wikipedia:66 Hypohidrosis is diminished sweating in response to appropriate stimuli. While hyperhidrosis is a... more...

MalaCards: Anhidrosis, also known as absence of sweating, is related to hypohidrosis and autonomic neuropathy. An important gene associated with Anhidrosis is NTRK1 (neurotrophic tyrosine kinase, receptor, type 1), and among its related pathways are Activation of TRKA receptors and Apoptosis and survival Anti apoptotic TNFs NF kB Bcl 2 pathway. The compounds cipa and mipafox have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and bone, and related mouse phenotypes are vision/eye and no phenotypic analysis.

Description from OMIM:48 206600

Aliases & Classifications for Anhidrosis

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Sources:
9Disease Ontology, 11DISEASES, 46Novoseek, 63UMLS, 48OMIM, 59SNOMED-CT, 41NCIt, 36MeSH, 28ICD9CM, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases


Aliases & Descriptions:

anhidrosis 9 11 46 63
absence of sweating 9
adiaphoresis 9


External Ids:

Disease Ontology9 DOID:11156
OMIM48 206600
NCIt41 C34385
MeSH36 D007007
ICD9CM28 705.0
ICD1026 L74.4

Related Diseases for Anhidrosis

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18GeneCards, 19GeneDecks
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Diseases related to Anhidrosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 118)
idRelated DiseaseScoreTop Affiliating Genes
1hypohidrosis30.6GLA
2autonomic neuropathy30.5NTRK1, NGF
3hereditary sensory neuropathy30.2NGF, NTRK1
4pyruvate kinase deficiency30.0PKLR
5multiple sclerosis29.8NGF, NGFR, MAPK10
6congenital insensitivity to pain with anhidrosis10.9
7neuropathy10.6
8alopecia10.3
9miliaria10.3
10horner's syndrome10.2
11dermatitis10.1
12ectodermal dysplasia10.1
13harlequin syndrome10.1
14neuroaxonal dystrophy10.1NGF, NTRK1
15rett syndrome10.1NGF, NTRK1
16sensory peripheral neuropathy10.1NGF, NTRK1
17polyneuropathy10.1ACHE
18thymus cancer10.1NTRK1, NGFR
19gaucher's disease10.1GLA, PKLR
20sialadenitis10.1
21cholinergic urticaria10.1
22impotence10.1
23leprosy10.1
24urticaria10.1
25vasculitis10.1
26postural hypotension10.1
27papillary thyroid carcinoma10.0NTRK1, MAPK10
28memory impairment10.0ACHE, NGF
29diabetic neuropathy10.0NTRK1, NGFR, NGF
30ganglioneuroma10.0NGF, NGFR, NTRK1
31prion disease10.0ACHE, NTRK1, NGF
32neuroblastoma10.0NTRK1, NGFR, NGF
33cholera10.0NGF, NTRK1, ACHE
34amyotrophic lateral sclerosis10.0NTRK1, NGFR, NGF
35prolactinoma10.0NGF, NGFR
36hirschsprung's disease10.0ACHE, NTRK1, NGFR
37myopathy10.0NGF, ACHE, PKLR
38huntington's disease10.0NGF, NGFR, ACHE
39cerebrovascular disease10.0GLA, MAPK10, NTRK1
40epilepsy syndrome10.0NGF, NGFR, ACHE
41thymoma10.0NTRK1, NGFR
42neurilemmoma10.0ACHE, NGFR
43dementia10.0MAPK10, ACHE, NGF
44polycystic kidney disease10.0MAPK10, MAPK1
45parkinson's disease10.0ACHE, NTRK1, NGFR, NGF
46thyroid cancer10.0NTRK1, MAPK10, MAPK1
47neuroepithelioma10.0NGF, MAPK10, MAPK1
48medulloblastoma10.0MAPK10, NTRK1, NGFR, NGF
49chronic myeloid leukemia10.0MAPK1, MAPK10, NTRK1
50schizophrenia10.0NGF, NTRK1, ACHE, MAPK10

Graphical network of the top 20 diseases related to Anhidrosis:



Diseases related to anhidrosis

Symptoms for Anhidrosis

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48OMIM
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Clinical features from OMIM:

206600

Drugs & Therapeutics for Anhidrosis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Anhidrosis

Drug clinical trials:

Search ClinicalTrials for Anhidrosis

Search NIH Clinical Center for Anhidrosis

Search CenterWatch for Anhidrosis

Genetic Tests for Anhidrosis

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Anatomical Context for Anhidrosis

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34MalaCards
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MalaCards organs/tissues related to Anhidrosis:

34
Skin, Testes, Bone, Spinal cord, Lung, T cells

Animal Models for Anhidrosis or affiliated genes

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Sources:
38MGI
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MGI Mouse Phenotypes related to Anhidrosis:

38 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.7ACHE, NTRK1, NGFR, NGF
2MP:00030128.4NGF, NTRK1, ACHE, MAPK10, ALOXE3
3MP:00107718.1NGF, NGFR, NTRK1, MAPK1, ALOXE3
4MP:00053697.8GLA, MAPK1, ACHE, NTRK1, NGFR, NGF
5MP:00053857.7NGF, NGFR, MAPK10, MAPK1, GLA
6MP:00053977.6NGFR, NTRK1, ACHE, PKLR, MAPK1
7MP:00053787.5NGF, NGFR, NTRK1, ACHE, MAPK1, ALOXE3
8MP:00036317.4NGF, NGFR, NTRK1, ACHE, MAPK10, MAPK1
9MP:00107687.2NGF, NGFR, NTRK1, ACHE, PKLR, MAPK1
10MP:00053867.2NGF, NGFR, NTRK1, ACHE, MAPK10, MAPK1
11MP:00053766.9NGF, NGFR, ACHE, PKLR, MAPK10, MAPK1

Publications for Anhidrosis

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53PubMed
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Articles related to Anhidrosis:

(show top 50)    (show all 243)
idTitleAuthorsYear
1
Old fractures in two patients with congenital insensitivity to pain with anhidrosis: radiological findings. (23478071)
2013
2
Acquired generalized anhidrosis: review of the literature and report of a case with lymphocytic hidradenitis and sialadenitis successfully treated with cyclosporine. (24191980)
2013
3
Nerve growth factor and the physiology ofA pain: lessons from congenital insensitivity to pain with anhidrosis. (22882139)
2012
4
Unilateral anhidrosis: a rare presentation of atrial myxoma? (23230264)
2012
5
Novel nonsense and frameshift NTRK1 gene mutations in Chinese patients with congenital insensitivity to pain with anhidrosis. (22653642)
2012
6
Right ptosis, anhidrosis, and miosis developed in a 49-year-old man with chronic dry cough for 2 months. (22796847)
2012
7
Anhidrosis after anterior retroperitoneal approach for L4-L5 artificial disc replacement. (21570302)
2011
8
A short in-frame deletion in NTRK1 tyrosine kinase domain caused by a novel splice site mutation in a patient with congenital insensitivity to pain with anhidrosis. (21708027)
2011
9
Evaluation of nonnociceptive sensation in patients with congenital insensitivity to pain with anhidrosis. (20013280)
2010
10
Nerve growth factor, pain, itch and inflammation: lessons from congenital insensitivity to pain with anhidrosis. (20977328)
2010
11
Clinical and genetic analysis of Korean patients with congenital insensitivity to pain with anhidrosis. (19618435)
2009
12
Nerve growth factor, interoception, and sympathetic neuron: lesson from congenital insensitivity to pain with anhidrosis. (19201660)
2009
13
Isolated generalised anhidrosis induced by postganglionic sympathetic skin nerve fibre degeneration: an incomplete Ross syndrome? (18356251)
2008
14
Novel missense, insertion and deletion mutations in the neurotrophic tyrosine kinase receptor type 1 gene (NTRK1) associated with congenital insensitivity to pain with anhidrosis. (18077166)
2008
15
Idiopathic generalized anhidrosis: a feature of panautonomic failure. (18797081)
2008
16
Congenital insensitivity to pain with anhidrosis and progressing acro-osteolysis: a case report with 7-year follow-up. (17199968)
2006
17
Clinical and genetic aspects of congenital insensitivity to pain with anhidrosis]. (15999564)
2005
18
A novel lymphocyte signaling defect: trk A mutation in the syndrome of congenital insensitivity to pain and anhidrosis (CIPA). (15163901)
2004
19
Idiopathic pure sudomotor failure: anhidrosis due to deficits in cholinergic transmission. (15505168)
2004
20
Intrasinus wood foreign body causing orbital cellulitis in congenital insensitivity to pain with anhidrosis syndrome. (14752319)
2004
21
Congenital insensitivity of pain with anhidrosis. (12619965)
2003
22
Post-herpetic neuralgia in a patient with congenital insensitivity to pain and anhidrosis. (14566502)
2002
23
Genetics of congenital insensitivity to pain with anhidrosis (CIPA) or hereditary sensory and autonomic neuropathy type IV. Clinical, biological and molecular aspects of mutations in TRKA(NTRK1) gene encoding the receptor tyrosine kinase for nerve growth factor. (12102460)
2002
24
Indolent corneal ulcers in a patient with congenital insensitivity to pain with anhidrosis: a case report and literature review. (11936447)
2002
25
Congenital insensitivity to pain with anhidrosis (CIPA): the spectrum of radiological findings. (11685437)
2001
26
Congenital insensitivity to pain with anhidrosis: an NGF/TrkA-related disorder. (11241480)
2001
27
Two novel mutant alleles of the gene encoding neurotrophic tyrosine kinase receptor type 1 (NTRK1) in a patient with congenital insensitivity to pain with anhidrosis: a splice junction mutation in intron 5 and cluster of four mutations in exon 15. (11139246)
2001
28
Neurophysiologic studies in congenital insensitivity to pain with anhidrosis. (11744315)
2001
29
Congenital insensitivity to pain with anhidrosis. (11483399)
2001
30
Congenital insensitivity to pain with anhidrosis (CIPA) in Israeli- Bedouins: genetic heterogeneity, novel mutations in the TRKA/NGF receptor gene, clinical findings, and results of nerve conduction studies. (10861667)
2000
31
The Gly571Arg mutation, associated with the autonomic and sensory disorder congenital insensitivity to pain with anhidrosis, causes the inactivation of the NTRK1/nerve growth factor receptor. (10567924)
2000
32
Complete paternal uniparental isodisomy for chromosome 1 revealed by mutation analyses of the TRKA (NTRK1) gene encoding a receptor tyrosine kinase for nerve growth factor in a patient with congenital insensitivity to pain with anhidrosis. (11071380)
2000
33
Congenital insensitivity to pain with anhidrosis. Report of a case and review of the literature. (10842874)
2000
34
Congenital insensitivity to pain with anhidrosis: ocular and systemic manifestations. (10088743)
1999
35
Traumatic Horner syndrome without anhidrosis. (10380140)
1999
36
Unilateral loss of facial flushing and sweating with contralateral anhidrosis: harlequin syndrome or Adie's syndrome? (8292878)
1993
37
Axonal degeneration of the peripheral nerves and postganglionic anhidrosis in a patient with multiple sclerosis. (1965353)
1990
38
Familial generalized anhidrosis. (2401613)
1990
39
Idiopathic acquired generalized anhidrosis: electron-microscopic and immunohistochemical studies and analysis of lectin-binding pattern of the cell membrane. (2721803)
1989
40
Clinical, clinicopathologic, and epidemiologic features of anhidrosis in central Florida Thoroughbred horses. (3506097)
1987
41
Equine anhidrosis: a survey of affected horses in Florida. (7068500)
1982
42
Studies on the mechanism of topical anhidrosis due to polyvalent cations. (19469924)
1981
43
The role of bacteria in anhidrosis. (4750804)
1973
44
Miliaria and anhidrosis. 3. Multiple small patches and the effects of different periods of occlusion. (5030233)
1972
45
Pruritus and acquired anhidrosis. Two unusual cases. (5822371)
1969
46
Congenital sensory neuropathy with anhidrosis. (4171106)
1968
47
Miliaria and anhidrosis. I. Experimental production in volunteers. (6062874)
1967
48
The significance of temporary and alternating ptosis, miosis and anhidrosis. (13272050)
1955
49
A form of ectodermal dysplasia; hypotrichosis with anhidrosis and anodontia]. (13023176)
1952
50
Tropical anidrotic asthenia (thermogenic anhidrosis) and its relationship to prickly heat. (20244419)
1946

Variations for Anhidrosis

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Expression for genes affiliated with Anhidrosis

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Anhidrosis

Search GEO for disease gene expression data for Anhidrosis.

Pathways for genes affiliated with Anhidrosis

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Sources:
51PathCards, 56Reactome, 61Thomson Reuters, 54QIAGEN, 31KEGG, 5Cell Signaling Technology, 39NCBI BioSystems Database, 58SinoBiological, 52PharmGKB, 62Tocris Bioscience, 55R&D Systems
See all sources

Pathways related to Anhidrosis according to GeneCards/GeneDecks:

(show top 50)    (show all 51)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.8NTRK1, NGF
2
Show member pathways
Apoptosis and survival Anti apoptotic TNFs NF kB IAP pathway61
9.6NGFR, NGF
39.3NTRK1, MAPK1
49.3MAPK1, NTRK1
59.3NTRK1, NGFR, NGF
69.1MAPK1, ACHE
7
Show member pathways
9.0MAPK10, MAPK1
8
Show member pathways
TRAIL signaling pathway39
9.0MAPK1, MAPK10
99.0MAPK10, MAPK1
10
Show member pathways
9.0MAPK1, MAPK10
119.0MAPK1, MAPK10
129.0MAPK1, MAPK10
13
Show member pathways
Cell cycle ESR1 regulation of G1 S transition61
Immune response MIF JAB1 signaling61
Cell cycle Cell cycle generic schema 61
9.0MAPK1, MAPK10
149.0MAPK10, MAPK1
15
Show member pathways
9.0MAPK10, MAPK1
16
Show member pathways
Apoptosis and survival Lymphotoxin beta receptor signaling61
9.0MAPK1, MAPK10
17
Show member pathways
9.0NGFR, NTRK1, MAPK10
18
Show member pathways
9.0MAPK1, NTRK1, NGF
19
Show member pathways
9.0NGF, NGFR, MAPK10
20
Show member pathways
9.0NGF, NTRK1, MAPK1
21
Show member pathways
9.0NGF, NTRK1, MAPK1
22
Show member pathways
8.8MAPK1, NTRK1, NGFR
238.8NTRK1, ACHE, MAPK1
248.8NGF, NGFR, MAPK1
25
Show member pathways
8.7MAPK1, MAPK10, NTRK1
268.7MAPK1, MAPK10, NTRK1
27
Show member pathways
8.6MAPK1, MAPK10, PKLR
28
Show member pathways
Transcription Receptor mediated HIF regulation61
Development CNTF receptor signaling61
Class IB PI3K non-lipid kinase events39
ErbB2/ErbB3 signaling events39
Development Growth hormone signaling via PI3K AKT and MAPK cascades61
Translation Regulation activity of EIF261
Regulation of lipid metabolism Insulin signaling generic cascades61
Transcription PPAR Pathway61
Cell adhesion PLAU signaling61
Translation Regulation activity of EIF4F61
8.6MAPK1, MAPK10, PKLR
29
Show member pathways
Apoptosis and survival TNFR1 signaling pathway61
TWEAK Signaling Pathway39
Apoptosis Modulation by HSP7039
HIV-1 Nef- Negative effector of Fas and TNF-alpha39
8.5MAPK1, MAPK10, NGFR
30
Show member pathways
8.5NGFR, MAPK10, MAPK1
31
Show member pathways
8.5ACHE, MAPK10, MAPK1
32
Show member pathways
Cytoskeleton remodeling Fibronectin binding integrins in cell motility61
Cytoskeleton remodeling Integrin outside in signaling61
Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases61
Cell adhesion Tight junctions61
Development MAG dependent inhibition of neurite outgrowth61
8.4MAPK1, NTRK1, NGFR, NGF
33
Show member pathways
8.4MAPK1, NTRK1, NGFR, NGF
34
Show member pathways
8.4NGF, NGFR, NTRK1, MAPK1
35
Show member pathways
Cytoskeleton remodeling FAK signaling61
Development Endothelin 1 EDNRA transactivation of EGFR61
8.3MAPK1, MAPK10, NTRK1, NGF
36
Show member pathways
8.3NGF, NTRK1, MAPK10, MAPK1
37
Show member pathways
8.3NGF, NTRK1, MAPK10, MAPK1
38
Show member pathways
MAPK signaling pathway39
8.3NGF, NTRK1, MAPK10, MAPK1
39
Show member pathways
8.2NGFR, NTRK1, MAPK10, MAPK1
40
Show member pathways
8.2MAPK1, MAPK10, NTRK1, NGFR
41
Show member pathways
8.2NGFR, NTRK1, MAPK10, MAPK1
42
Show member pathways
8.2MAPK1, MAPK10, NTRK1, NGFR
43
Show member pathways
8.2NGFR, NTRK1, MAPK10, MAPK1
44
Show member pathways
8.2MAPK1, MAPK10, NTRK1, NGFR
45
Show member pathways
8.2NGFR, NTRK1, MAPK10, MAPK1
46
Show member pathways
8.2MAPK1, MAPK10, NTRK1, NGFR
47
Show member pathways
8.1MAPK1, MAPK10, NGFR, NGF
48
Show member pathways
8.1NGF, NGFR, MAPK10, MAPK1
49
Show member pathways
Development EGFR signaling via PIP361
Development PDGF signaling via MAPK cascades61
Apoptosis and survival Anti apoptotic action of membrane bound ESR161
Signaling of Hepatocyte Growth Factor Receptor39
Development EGFR signaling via small GTPases61
Development Neurotrophin family signaling61
Apoptosis and survival NGF signaling pathway61
Apoptosis and survival Role of CDK5 in neuronal death and survival61
7.8NGF, NGFR, NTRK1, MAPK10, MAPK1
507.8MAPK1, MAPK10, NTRK1, NGFR, NGF

Compounds for genes affiliated with Anhidrosis

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Sources:
46Novoseek, 62Tocris Bioscience, 12DrugBank, 25HMDB, 30IUPHAR, 52PharmGKB, 3BitterDB
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Compounds related to Anhidrosis according to GeneCards/GeneDecks:

(show top 50)    (show all 97)
idCompoundScoreTop Affiliating Genes
1cipa4610.1NTRK1, NGF
2mipafox469.9ACHE, NGF
3estradiol valerate469.9NGFR, NGF
4propentofylline469.8NTRK1, NGF
5ana 12629.7NGF, NGFR, NTRK1
6tlqp 21629.7NGF, NGFR, NTRK1
7bdnf (human)629.7NGF, NTRK1, NGFR
8gnf 5837629.7NTRK1, NGFR, NGF
97,8-dihydroxyflavone62 4610.7NTRK1, NGFR, NGF
10ag 879469.6NGF, NTRK1, MAPK10
111,4-diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene469.4MAPK10, MAPK1
12pyridinylimidazole469.4MAPK10, MAPK1
13gw-5074469.4MAPK10, MAPK1
14rasagiline46 1210.4MAPK10, ACHE, NGF
15ganglioside469.3GLA, NTRK1, NGFR, NGF
16kn 93469.2MAPK1, MAPK10
17choline46 25 1211.1NGF, NGFR, NTRK1, ACHE
18farnesylthiosalicylic acid30 4610.1MAPK1, MAPK10
19olomoucine46 1210.0MAPK1, MAPK10, NGF
20pdtc468.9NGF, MAPK10, MAPK1
21anisomycin46 129.9NGF, MAPK10, MAPK1
22dopamine46 30 25 1211.9NGF, NGFR, NTRK1, ACHE
23nicotine46 30 52 1211.8MAPK10, ACHE, NGFR, NGF
24matrigel468.8NGF, NGFR, NTRK1, MAPK1
25c2ceramide468.8MAPK1, MAPK10, NTRK1, NGF
26arachidonic acid46 30 25 1211.8NGFR, NTRK1, MAPK10, ALOXE3
27pd 98,059468.7NGF, NTRK1, MAPK10, MAPK1
28ly294002468.6NGF, NTRK1, MAPK10, MAPK1
29phorbol468.6NGFR, NTRK1, MAPK10, MAPK1
30genistein46 30 62 3 25 1213.6MAPK1, MAPK10, NTRK1, NGF
31gf 109203x46 629.6NGF, MAPK10, MAPK1
32acetylcholine46 52 30 25 1212.5NGF, NGFR, NTRK1, ACHE, MAPK10
33forskolin46 52 1210.4MAPK1, MAPK10, NGFR, NGF
34adenylate468.3MAPK1, MAPK10, NTRK1, NGF
35k252a468.3MAPK1, MAPK10, NTRK1, NGFR, NGF
36thymidine46 259.2NGF, NGFR, MAPK10, MAPK1
37phosphotyrosine468.2NGF, NGFR, NTRK1, MAPK10, MAPK1
3812-o-tetradecanoylphorbol 13-acetate468.2NGF, NGFR, NTRK1, MAPK10, MAPK1
39wortmannin468.2NGF, NGFR, NTRK1, MAPK10, MAPK1
40phosphoinositide468.2NGF, NGFR, NTRK1, MAPK10, MAPK1
41vegf468.2NGF, NGFR, NTRK1, MAPK10, MAPK1
42phosphatidylinositol468.2NGF, NGFR, NTRK1, MAPK10, MAPK1
43retinoic acid46 259.1NGF, NGFR, NTRK1, MAPK10, MAPK1
44nmda46 309.0NGF, NGFR, ACHE, MAPK10, MAPK1
45glutamate468.0NGF, NGFR, NTRK1, ACHE, MAPK1, GLA
46ceramide467.9NGF, NGFR, NTRK1, MAPK10, MAPK1, GLA
47threonine467.9NGF, NGFR, NTRK1, MAPK10, MAPK1, GLA
48tyrosine467.7NGF, NGFR, NTRK1, PKLR, MAPK10, MAPK1
49calcium46 52 25 1210.2NGF, NGFR, NTRK1, MAPK10, MAPK1, GLA
50serine467.0NGF, NGFR, NTRK1, ACHE, PKLR, MAPK10

GO Terms for genes affiliated with Anhidrosis

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Sources:
17Gene Ontology
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Cellular components related to Anhidrosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell surfaceGO:0099869.1ACHE, NTRK1, NGFR
2endosomeGO:0057689.0NTRK1, NGFR, NGF

Biological processes related to Anhidrosis according to GeneCards/GeneDecks:

(show all 21)
idNameGO IDScoreTop Affiliating Genes
1response to electrical stimulusGO:05160210.1NGF, NTRK1
2response to radiationGO:00931410.1NTRK1, NGF
3activation of phospholipase C activityGO:0072029.9NTRK1, NGF
4regulation of cysteine-type endopeptidase activity involved in apoptotic processGO:0432819.9NGFR, NGF
5positive regulation of axonogenesisGO:0507729.9NGFR, NGF
6transmembrane receptor protein tyrosine kinase signaling pathwayGO:0071699.8NTRK1, NGF
7extrinsic apoptotic signaling pathway via death domain receptorsGO:0086259.8NGF, NGFR
8negative regulation of cell cycleGO:0457869.8NGFR, NGF
9regulation of axonogenesisGO:0507709.4ACHE, NGFR, NGF
10activation of MAPKK activityGO:0001869.3MAPK1, NTRK1, NGF
11Ras protein signal transductionGO:0072659.3MAPK1, NTRK1, NGF
12regulation of sequence-specific DNA binding transcription factor activityGO:0510909.2MAPK10, MAPK1
13stress-activated MAPK cascadeGO:0514039.2MAPK10, MAPK1
14small GTPase mediated signal transductionGO:0072649.2MAPK1, NTRK1, NGF
15sensory perception of painGO:0192339.2NGF, MAPK1, ALOXE3
16toll-like receptor 10 signaling pathwayGO:0341669.0MAPK10, MAPK1
17toll-like receptor TLR6:TLR2 signaling pathwayGO:0381249.0MAPK1, MAPK10
18axon guidanceGO:0074119.0MAPK1, NTRK1, NGFR
19toll-like receptor 5 signaling pathwayGO:0341468.9MAPK10, MAPK1
20neurotrophin TRK receptor signaling pathwayGO:0480118.8NGF, NGFR, NTRK1, MAPK1
21toll-like receptor TLR1:TLR2 signaling pathwayGO:0381238.7MAPK1, MAPK10

Molecular functions related to Anhidrosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nerve growth factor bindingGO:0484069.3NTRK1, NGFR
2protein bindingGO:0055156.9GLA, ALOXE3, MAPK1, MAPK10, ACHE, NTRK1

Products for genes affiliated with Anhidrosis

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  • Antibodies
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Sources for Anhidrosis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet