Summaries for Anovulation

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Wikipedia:65 An anovulatory cycle is a menstrual cycle during which the ovaries do not release an oocyte. Therefore,... more...

MalaCards based summary: Anovulation is related to hyperandrogenism and polycystic ovary syndrome. An important gene associated with Anovulation is CGA (glycoprotein hormones, alpha polypeptide), and among its related pathways are Hormone ligand-binding receptors and Peptide hormone metabolism. The compounds altrenogest and deslorelin have been mentioned in the context of this disorder. Affiliated tissues include ovary, pituitary and breast.

Aliases & Classifications for Anovulation

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Sources:
10Disease Ontology, 12DISEASES, 45Novoseek, 62UMLS, 57SNOMED-CT, 40NCIt, 35MeSH
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Anovulation, Aliases & Descriptions:

Name: Anovulation 10 12 45 62


External Ids:

Disease Ontology10 DOID:3781
NCIt40 C34388
SNOMED-CT57 34571000
MeSH35 D000858

Related Diseases for Anovulation

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Diseases related to Anovulation via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 78)
idRelated DiseaseScoreTop Affiliating Genes
1hyperandrogenism30.8CGA, SHBG, GNRH1, CYP21A2
2polycystic ovary syndrome30.8CYP21A2, GNRH1, SHBG, GHRL, CGA
3infertility30.8CYP21A2, GNRH1, SHBG, CGA
4amenorrhea30.7GNRH1, SHBG
5obesity30.4GHRL, SHBG, CYP21A2
6endometriosis30.3CGA, GNRH1
7ovarian disease30.3CGA, SHBG, GNRH1
8hyperprolactinemia30.3GNRH1, SHBG, CGA
9breast cancer30.2GHRL, SHBG, GNRH1
10ovarian cyst30.0GNRH1, CGA
11hypothyroidism30.0SHBG, CGA
12pituitary adenoma29.9CGA, GHRL, GNRH1
13glucose intolerance29.9GHRL, SHBG
14hyperinsulinism29.9GHRL, SHBG, GNRH1
15oligomenorrhea29.9CYP21A2, GNRH1, SHBG
16hypogonadism29.9GNRH1, SHBG, GHRL, CGA
17adenoma29.8CGA, GHRL, SHBG, GNRH1, CYP21A2
18vaginitis10.3
19blindness10.3
20acne10.0SHBG
21alopecia10.0SHBG
22hypothalamic disease10.0GNRH1, CGA
23penis agenesis10.0CGA, GNRH1
24ovarian hyperstimulation syndrome10.0CGA, GNRH1
25oligospermia10.0CGA, GNRH1
26abrikosov's tumor10.0GNRH1, CGA
27kallmann syndrome10.0GNRH1, CGA
28luteoma10.0CGA, CYP21A2
29germinoma10.0CGA, CYP21A2
30prolactinoma10.0GNRH1, CGA
31hypospadias10.0CGA, CYP21A2
32adrenal gland hyperfunction10.0CYP21A2, GHRL
33congenital adrenal hyperplasia10.0GNRH1, CYP21A2
34hashimoto thyroiditis10.0GHRL, CYP21A2
35androgen insensitivity10.0SHBG, CGA
36pituitary tumors10.0GNRH1, GHRL
37sexual disorder10.0GNRH1, SHBG
38celiac disease10.0GHRL, CYP21A2
39hypoglycemia10.0GHRL, GNRH1
40premature ovarian failure10.0GNRH1, SHBG
41testicular cancer10.0CGA, SHBG
42alopecia, androgenetic, 110.0SHBG, CYP21A2
43acanthosis nigricans10.0SHBG, CYP21A2
44anorexia nervosa10.0SHBG, GHRL
45non-suppurative otitis media10.0GHRL, SHBG
46male infertility10.0SHBG, GNRH1
47leydig cell tumor10.0CYP21A2, GNRH1, CGA
48cushing's syndrome10.0CYP21A2, GNRH1, GHRL
49choriocarcinoma10.0CGA, GNRH1
50varicocele10.0GNRH1, SHBG, CGA

Graphical network of the top 20 diseases related to Anovulation:



Diseases related to anovulation

Symptoms for Anovulation

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Drugs & Therapeutics for Anovulation

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Drug clinical trials:

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Genetic Tests for Anovulation

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Anatomical Context for Anovulation

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MalaCards organs/tissues related to Anovulation:

33
Ovary, Pituitary, Breast, Testes, Brain

Animal Models for Anovulation or affiliated genes

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Publications for Anovulation

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Articles related to Anovulation:

(show top 50)    (show all 305)
idTitleAuthorsYear
1
Accounting for Anovulation and Vaginal Thinning During Depot Medroxyprogesterone Acetate Use. (25217405)
2014
2
Pregnancy complications and metabolic disease in women with clomiphene citrate-resistant anovulation randomized to receive laparoscopic electrocautery of the ovaries or ovulation induction with gonadotropins: a 10-year follow-up. (24268702)
2014
3
British Fertility Society. 'Ovulation induction in WHO Type 1 anovulation: Guidelines for practice'. Produced on behalf of the BFS Policy and Practice Committee. (24245485)
2013
4
Progestogens with or without oestrogen for irregular uterine bleeding associated with anovulation. (22972055)
2012
5
Disruption of periovulatory FSH and LH surges during induced anovulation by an inhibitor of prostaglandin synthesis in mares. (21571458)
2011
6
Detection of anovulation by heatmount detectors and transrectal ultrasonography before treatment with progesterone in a timed insemination protocol. (18565948)
2008
7
Does metformin modify ovarian responsiveness during exogenous FSH ovulation induction in normogonadotrophic anovulation? A placebo-controlled double-blind assessment. (15817918)
2005
8
Oral anti-oestrogens and medical adjuncts for subfertility associated with anovulation. (15674894)
2005
9
A randomized clinical trial of treatment of clomiphene citrate-resistant anovulation with the use of oral contraceptive pill suppression and repeat clomiphene citrate treatment. (12824973)
2003
10
The effectiveness and safety of recombinant human LH to support follicular development induced by recombinant human FSH in WHO group I anovulation: evidence from a multicentre study in Spain. (11726569)
2001
11
Lactational amenorrhea/anovulation and some of their determinants: a comparison of well-nourished and undernourished women. (11476779)
2001
12
Nutritionally induced anovulation in beef Heifers: ovarian and endocrine function during realimentation and resumption of ovulation. (10775198)
2000
13
New hyperprolactinemia and anovulation model in common marmoset (Callithrix jacchus) and effect of cabergoline. (10096770)
1999
14
Extended clomiphene citrate (CC) and prednisone for the treatment of chronic anovulation resistant to CC alone. (9093187)
1997
15
Women with functional hypothalamic amenorrhea but not other forms of anovulation display amplified cortisol concentrations. (9176439)
1997
16
The effect of alprazolam on serum cortisol and luteinizing hormone pulsatility in normal women and in women with stress-related anovulation. (7883836)
1995
17
Lactational anovulation in non-human primates: restriction of nursing inhibits Prl secretion without precipitating the return of ovulatory menstrual cyclicity in cynomolgus monkeys. (7796594)
1995
18
A comparative prospective study of conventional regimen with chronic low-dose administration of follicle-stimulating hormone for anovulation associated with polycystic ovary syndrome. (7890055)
1995
19
Postpartum lactational anovulation in a nonhuman primate (Macaca fascicularis): endogenous opiate mediation of suckling-induced hyperprolactinemia. (1619032)
1992
20
Gonadotropin releasing hormone loading test with bromocryptin therapy: a new possibility in the differential diagnosis of normo-prolactinaemic anovulation]. (1625857)
1992
21
Atmospheric temperature & anovulation in south Indian women with primary infertility. (1597328)
1992
22
The association of anovulation and endometriosis in the infertile female. (2619687)
1989
23
The effects of an aromatase inhibitor and a 5 alpha-reductase inhibitor upon the occurrence of polyovular follicles, persistent anovulation, and permanent vaginal stratification in mice treated neonatally with testosterone. (3196799)
1988
24
Endometrial carcinoma following chronic anovulation in a premenopausal woman with systemic lupus erythematosus. (3239388)
1988
25
Changing pituitary reactivity to follicle-stimulating hormone and luteinizing hormone-releasing hormone after induced ovulatory cycles and after anovulation in patients with polycystic ovarian disease. (3119650)
1987
26
Circadian variations of luteinizing hormone can have two different profiles in adolescent anovulation. (3114303)
1987
27
Effects of intermittent injections of LHRH on secretory patterns of LH and FSH and ovarian follicular growth during postpartum anovulation in suckled beef cows. (3087926)
1986
28
Anovulation in postpartum suckled beef cows. II. Associations among binding of 125I-labeled gonadotropins to granulosa and thecal cells, and concentrations of steroids in serum and various sized ovarian follicles. (3009380)
1986
29
Pulsatile gonadotropin secretion in women with hypothalamic amenorrhea: evidence that reduced frequency of gonadotropin-releasing hormone secretion is the mechanism of persistent anovulation. (3900122)
1985
30
Interpretation of single progesterone measurement in diagnosis of anovulation and defective luteal phase. (6423124)
1984
31
Anovulation in female rats induced by neonatal administration of the catechol estrogens, 2-hydroxy-estradiol and 4-hydroxy-estradiol. (6196675)
1983
32
Prevention of continuous light-induced anovulation in rats by early exposure to continuous light. (6640025)
1983
33
Anovulation and oviductal hyperplasia in rats treated with clomiphene citrate 5 days after birth. (532522)
1979
34
Use of bromocriptine in hyperprolactinaemic anovulation and related disorders. (378649)
1979
35
Etiology of anovulation in the immature alloxan-diabetic rat treated with pregnant mare's serum gonadotropin: absence of the preovulatory luteinizing hormone surge. (744054)
1978
36
Kepone, mirex, dieldrin, and aldrin: estrogenic activity and the induction of persistent vaginal estrus and anovulation in rats following neonatal treatment. (79483)
1978
37
Anovulation and increased androgenic activity as breast cancer risk in women with fibrocystic disease of the breast. (679211)
1978
38
Endometriosis and anovulation: a coexisting problem in the infertile female. (1275031)
1976
39
Serum corticosterone in rats with delayed anovulation. (988105)
1976
40
An assessment of urinary and plasma steroid estimations for monitoring treatment of anovulation with gonadotrophins. (4411958)
1974
41
The effect of intravenous synthetic luteinizing hormone releasing hormone (LHRH) in infertile women with anovulation. (4601472)
1974
42
Results of treatment of longstanding oligomenorrhea and persistent anovulation with clomiphene citrate. (4795075)
1973
43
Anovulation. What price fertility? (5073459)
1972
44
Clinical results with human gonadotrophins in anovulation, using two alternative dosage schemes. (5014975)
1972
45
Treatment of anovulation in the Stein-Leventhal syndrome. Analysis of 90 cases. (5548552)
1971
46
Syndrome of anovulation following the oral contraceptives. (4951888)
1967
47
Clinical effects of clomiphene in anovulation. (5925037)
1966
48
ANOVULATION. (14180863)
1964
49
The problem of anovulation in private practice. (13538780)
1958
50
A survey of general and ovarian sterility with special reference to anovulation. (20250327)
1947

Variations for Anovulation

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Expression for genes affiliated with Anovulation

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Search GEO for disease gene expression data for Anovulation.

Pathways for genes affiliated with Anovulation

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Compounds for genes affiliated with Anovulation

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Compounds related to Anovulation according to GeneCards/GeneDecks:

(show top 50)    (show all 107)
idCompoundScoreTop Affiliating Genes
1altrenogest459.9GNRH1, CGA
2deslorelin459.8GNRH1, CGA
3metrodin459.8CGA, GNRH1
4pergonal459.8CGA, GNRH1
5antarelix45 3010.8GNRH1, CGA
6ganirelix45 3010.7CGA, GNRH1
7d-trp6-lhrh459.6CGA, GNRH1
8epitestosterone459.5CGA, SHBG
9naloxone45 30 51 1312.3CGA, GNRH1, GHRL
10nafarelin45 61 30 1312.3CYP21A2, GNRH1, CGA
11opiate459.3CGA, GHRL, GNRH1
12goserelin45 30 1311.1CGA, GNRH1, SHBG
13flutamide45 61 1311.1GNRH1, SHBG, CGA
14bromocriptine45 30 1311.0CGA, GNRH1, SHBG
15diethylstilbestrol45 30 1311.0GNRH1, SHBG, CGA
16cyproteroneacetate459.0GHRL, SHBG, GNRH1
1717-hydroxypregnenolone459.0SHBG, CYP21A2, CGA
1811 deoxycortisol459.0CYP21A2, SHBG, CGA
19triiodothyronine458.9CGA, SHBG, GHRL
20phenytoin45 51 30 1311.9CGA, SHBG, CYP21A2
21spironolactone45 61 30 51 1312.9CYP21A2, SHBG, GNRH1
22progestin458.9CGA, GNRH1, SHBG
23c-peptide458.8CYP21A2, GHRL, SHBG
24dhea458.8CYP21A2, SHBG, GHRL
25mifepristone45 30 61 1311.8GNRH1, CGA, SHBG
26ribonucleic acid458.7CGA, GNRH1, CYP21A2, GHRL
27metformin45 51 1310.6GHRL, SHBG, CGA, GNRH1
28leuprolide acetate458.5CGA, SHBG, GNRH1, CYP21A2
29clomiphene citrate458.5CGA, SHBG, GNRH1, CYP21A2
3017-hydroxyprogesterone45 269.5CGA, SHBG, GNRH1, CYP21A2
31androstenedione45 269.5CYP21A2, GNRH1, SHBG, CGA
32dihydrotestosterone45 30 26 1311.5SHBG, CGA, CYP21A2, GNRH1
33lactate458.4GHRL, CGA, SHBG, GNRH1
34hydrocortisone45 3 61 1311.4CYP21A2, SHBG, GHRL
35dopamine45 30 26 1311.4SHBG, GNRH1, CGA, GHRL
36acth458.4CYP21A2, SHBG, GHRL, GNRH1
37creatinine458.4CGA, GNRH1, GHRL, SHBG
38adenylate458.3GHRL, CGA, GNRH1, SHBG
39progesterone45 30 61 26 1312.1CGA, GNRH1, SHBG, CYP21A2
40dexamethasone45 51 30 1311.0GHRL, SHBG, GNRH1, CYP21A2
41dehydroepiandrosterone sulfate458.0CGA, GHRL, SHBG, CYP21A2, GNRH1
42thyroxine45 269.0SHBG, GHRL, CGA, GNRH1, CYP21A2
43gnrh458.0GHRL, CYP21A2, GNRH1, CGA, SHBG
44epinephrine45 26 1310.0CGA, SHBG, GHRL, GNRH1, CYP21A2
45norepinephrine45 26 1310.0SHBG, GHRL, CGA, GNRH1, CYP21A2
46estradiol45 26 1310.0CGA, GHRL, SHBG, GNRH1, CYP21A2
47testosterone45 61 26 1310.9GHRL, SHBG, GNRH1, CYP21A2, CGA
48arginine457.9GHRL, CGA, CYP21A2, GNRH1, SHBG
49estrogen457.9CGA, GHRL, GNRH1, SHBG, CYP21A2
50steroid457.8SHBG, GNRH1, CYP21A2, CGA

GO Terms for genes affiliated with Anovulation

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Cellular components related to Anovulation according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055768.2CGA, GHRL, SHBG, GNRH1

Molecular functions related to Anovulation according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051799.5CGA, GNRH1

Products for genes affiliated with Anovulation

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Sources for Anovulation

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4CDC
15ExPASy
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24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet