Aliases & Classifications for Anoxia

MalaCards integrated aliases for Anoxia:

Name: Anoxia 50 69

External Ids:

UMLS 69 C0003130

Summaries for Anoxia

NINDS : 50 Cerebral hypoxia refers to a condition in which there is a decrease of oxygen supply to the brain even though there is adequate blood flow. Drowning, strangling, choking, suffocation, cardiac arrest, head trauma, carbon monoxide poisoning, and complications of general anesthesia can create conditions that can lead to cerebral hypoxia. Symptoms of mild cerebral hypoxia include inattentiveness, poor judgment, memory loss, and a decrease in motor coordination. Brain cells are extremely sensitive to oxygen deprivation and can begin to die within five minutes after oxygen supply has been cut off. When hypoxia lasts for longer periods of time, it can cause coma, seizures, and even brain death.  In brain death, there is no measurable activity in the brain, although cardiovascular function is preserved. Life support is required for respiration.

MalaCards based summary : Anoxia is related to ischemia and cerebral hypoxia, and has symptoms including symptoms, labored breathing and respiratory distress. An important gene associated with Anoxia is SIRT2 (Sirtuin 2), and among its related pathways/superpathways are Selenium Micronutrient Network and Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF). The drugs Dopamine and Nitric Oxide have been mentioned in the context of this disorder. Affiliated tissues include brain, lung and kidney, and related phenotypes are Strongly decreased CFP-tsO45G cell surface transport and endocrine/exocrine gland

Wikipedia : 72 The term anoxia means a total depletion in the level of oxygen, an extreme form of hypoxia or \"low... more...

Related Diseases for Anoxia

Diseases related to Anoxia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 ischemia 29.6 ICAM1 NOS2 SOD1 XDH
2 cerebral hypoxia 11.3
3 acute mountain sickness 11.0
4 neuronitis 10.5
5 hypoxia 10.5
6 endotheliitis 10.4
7 cerebritis 10.4
8 papillomatosis, confluent and reticulated 10.2
9 peyronie disease 10.2 NOS2 SOD1
10 retinal vasculitis 10.1 NOS2 SOD1
11 myocardial stunning 10.1 KCNJ5 SOD1
12 arthus reaction 10.1 ICAM1 NOS2
13 mild pre-eclampsia 10.1 SOD1 XDH
14 eales disease 10.0 NOS2 SOD1
15 aging 10.0
16 status epilepticus 9.9
17 cardiac arrest 9.9
18 hypoglycemia 9.8
19 athetosis 9.8
20 glioblastoma 9.8
21 cerebral palsy 9.8
22 encephalopathy 9.8
23 hepatitis 9.8
24 microvascular complications of diabetes 1 9.8 CTGF ICAM1
25 heart disease 9.7
26 dystonia 9.7
27 neonatal hypoxic and ischemic brain injury 9.7
28 cortical blindness 9.7
29 periventricular leukomalacia 9.7
30 endocardial fibroelastosis 9.7
31 hepatic encephalopathy 9.7
32 rett syndrome 9.7
33 melanoma 9.7
34 hearing loss, noise-induced 9.7
35 encephalomalacia 9.7
36 glioma 9.7
37 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.7
38 vaginitis 9.7
39 leukomalacia 9.7
40 pulmonary hypertension 9.7
41 kernicterus 9.7
42 streptococcal group a invasive disease 9.7
43 brain injury 9.7
44 cerebral atrophy 9.7
45 brain ischemia 9.7
46 retinitis 9.7
47 mutism 9.7
48 malignant glioma 9.7
49 hyperglycemia 9.7
50 myoclonus 9.7

Graphical network of the top 20 diseases related to Anoxia:



Diseases related to Anoxia

Symptoms & Phenotypes for Anoxia

UMLS symptoms related to Anoxia:


symptoms, labored breathing, respiratory distress, signs and symptoms, respiratory, dyspnea, cyanosis, anoxemia

GenomeRNAi Phenotypes related to Anoxia according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Strongly decreased CFP-tsO45G cell surface transport GR00360-A-2 8.92 CTGF EEF2K OXTR SIRT2

MGI Mouse Phenotypes related to Anoxia:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.97 ACOX1 CTGF EEF2K ICAM1 NOS2 OXTR
2 cellular MP:0005384 9.91 CTGF EEF2K ICAM1 NOS2 SIRT2 SOD1
3 homeostasis/metabolism MP:0005376 9.86 ACOX1 CTGF EEF2K ICAM1 NOS2 SIRT2
4 integument MP:0010771 9.7 CTGF ICAM1 NOS2 OXTR SIRT2 SOD1
5 muscle MP:0005369 9.35 ICAM1 NOS2 OXTR SOD1 XDH
6 neoplasm MP:0002006 9.02 SOD1 ACOX1 ICAM1 NOS2 SIRT2

Drugs & Therapeutics for Anoxia

Drugs for Anoxia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 581)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 4,Phase 2,Phase 1 51-61-6, 62-31-7 681
2
Nitric Oxide Approved Phase 4,Phase 3,Phase 1,Phase 2 10102-43-9 145068
3
Zinc Approved, Investigational Phase 4,Phase 2,Phase 3 7440-66-6 32051 23994
4
Epinephrine Approved, Vet_approved Phase 4,Phase 2,Phase 3 51-43-4 5816
5
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2 59467-70-8 4192
6
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
7
Amlodipine Approved Phase 4,Phase 2,Phase 3 88150-42-9 2162
8
Metoprolol Approved, Investigational Phase 4,Phase 2,Phase 3 51384-51-1, 37350-58-6 4171
9
Atropine Approved, Vet_approved Phase 4 5908-99-6, 51-55-8 174174
10
Succinylcholine Approved Phase 4 306-40-1 5314
11
Terbutaline Approved Phase 4 23031-25-6 5403
12
Bosentan Approved, Investigational Phase 4,Phase 1 147536-97-8 104865
13
Adenosine Approved, Investigational Phase 4,Phase 1,Phase 2 58-61-7 60961
14
Ipratropium Approved Phase 4 22254-24-6, 60205-81-4 43232
15
Angiotensin II Approved, Investigational Phase 4,Phase 2 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
16
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
17
Budesonide Approved Phase 4,Phase 1 51333-22-3 5281004 63006
18
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3 2078-54-8 4943
19
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 1 1994-09-7, 94-09-7 2337
20
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 437-38-7 3345
21
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
22
Acetylcysteine Approved, Investigational Phase 4,Early Phase 1 616-91-1 12035
23
Bromhexine Approved Phase 4 3572-43-8
24 Racepinephrine Approved Phase 4,Phase 2,Phase 3 329-65-7
25
Indomethacin Approved, Investigational Phase 4,Phase 1,Phase 2 53-86-1 3715
26
Dipyridamole Approved Phase 4 58-32-2 3108
27
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
28
Nicorandil Approved, Investigational Phase 4 65141-46-0 47528
29
Nifedipine Approved Phase 4 21829-25-4 4485
30
Captopril Approved Phase 4 62571-86-2 44093
31
Losartan Approved Phase 4,Phase 2 114798-26-4 3961
32
Telmisartan Approved, Investigational Phase 4 144701-48-4 65999
33
Carvedilol Approved, Investigational Phase 4 72956-09-3 2585
34
Bisoprolol Approved Phase 4 66722-44-9 2405
35
Nebivolol Approved, Investigational Phase 4 152520-56-4, 118457-14-0, 99200-09-6 71301
36
Memantine Approved, Investigational Phase 4,Phase 2 19982-08-2 4054
37
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
38
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Early Phase 1 76631-46-4, 113775-47-6 5311068 56032 68602
39
Prednisolone Approved, Vet_approved Phase 4,Phase 2 50-24-8 5755
40
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 22916-47-8 4189
41
Acetazolamide Approved, Vet_approved Phase 4,Phase 2,Phase 3 59-66-5 1986
42
Dutasteride Approved, Investigational Phase 4 164656-23-9 6918296 152945
43
Remifentanil Approved Phase 4 132875-61-7 60815
44
Bupivacaine Approved, Investigational Phase 4 38396-39-3, 2180-92-9 2474
45
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
46
Oseltamivir Approved Phase 4,Phase 2 196618-13-0, 204255-11-8 65028
47
Methazolamide Approved Phase 4,Phase 1,Phase 2 554-57-4 4100
48
Benzydamine Approved Phase 4 642-72-8, 100-46-9 7504
49
Everolimus Approved Phase 4,Phase 2,Phase 1 159351-69-6 6442177
50
Alfentanil Approved, Illicit Phase 4 71195-58-9 51263

Interventional clinical trials:

(show top 50) (show all 1132)

# Name Status NCT ID Phase Drugs
1 Intermittent Hypoxia 2: Cardiovascular and Metabolism Unknown status NCT02058823 Phase 4 Placebo;Placebo;Valsartan;Amlodipine
2 Comparison of Efficacy Different Treatment Regimens in Pulmonary Hypertension Secondary to Lung Disease and or Hypoxia Unknown status NCT01449253 Phase 4 Sildenafil;Bosentan
3 Sevoflurane Decreases the Risk of Postoperative Delirium After Cerebral Hypoxemia During Surgery Unknown status NCT02133638 Phase 4 Sevoflurane;Propofol
4 Continuous Intravenous Sufentanil Infusion for Postoperative Pain Management Following Tonsillectomy or Adeno-tonsillectomy in Children Unknown status NCT02205580 Phase 4 continuous intravenous sufentanil 0.02μg•kg-1•h-1 infusion;continuous intravenous sufentanil 0.03μg•kg-1•h-1 infusion;continuous intravenous sufentanil 0.04μg•kg-1•h-1 infusion
5 Sodium Bicarbonate in Cardiopulmonary Resuscitation Unknown status NCT01377337 Phase 4 sodium bicarbonate
6 Postpartum Oxygen Inhalation for the Treatment of Postpartum Haemorrhage Unknown status NCT01180192 Phase 4 oxygen
7 Home Oxygen Therapy in Bronchiolitis Unknown status NCT01216553 Phase 4
8 Effect of Acute Hyperglycemia on Renal Tissue Oxygenation Unknown status NCT02346149 Phase 4
9 CPAP in Liver Transplant Unknown status NCT00510770 Phase 4
10 Atropine Versus no Atropine for Neonatal Rapid Sequence Intubation Unknown status NCT01595399 Phase 4 atropine;Placebo
11 LTOT in COPD Patients With Moderate Chronic Hypoxemia and Chronic Heart Failure Unknown status NCT00668408 Phase 4
12 AZ, MZ, and the Pulmonary System Response to Hypoxia Completed NCT02760121 Phase 4 Acetazolamide;Methazolamide;Placebo
13 5-hydroxytryptophan and Creatine for Treatment Resistant Depression Associated With Hypoxia in Females Completed NCT02356107 Phase 4 5-hydroxytryptophan and Creatine monohydrate
14 Effect of Systemic Hypoxia and Hyperoxia on Retinal Oxygen Saturation Completed NCT01692821 Phase 4 100% oxygen breathing;15% oxygen in N2 breathing;12% oxygen in N2 breathing
15 Lipo-prostaglandin E1 Improves Renal Hypoxia Evaluated by BOLD-MRI in Patients With Diabetic Nephropathy Completed NCT02628106 Phase 4 Lipo-PGE1
16 Acute Ventilatory Response to Hypoxia During Sedation With Dexmedetomidine Compared to Propofol in Healthy Male Volunteers Completed NCT01873612 Phase 4
17 Effects of Nebivolol Versus Carvedilol on Cardiopulmonary Function at High Altitude in Healthy Subjects. Completed NCT00924833 Phase 4 placebo;Carvedilol;Nebivolol
18 Muscle Fatigue and Carbonic Anhydrase Inhibitors Completed NCT02758470 Phase 4 Acetazolamide;Methazolamide
19 Ambulatory Oxygen Effects on Muscles in COPD Completed NCT01722370 Phase 4 Oxygen;Medical air equivalent
20 Doxapram as an Additive to Propofol Sedation in Sedation for ERCP Completed NCT02171910 Phase 4 Doxapram;Placebo
21 CPAP in SAHS Patients With Hypertension Completed NCT02398032 Phase 4
22 Nebivolol Versus Bisoprolol Versus Carvedilol in Heart Failure Completed NCT00517725 Phase 4 carvedilol;bisoprolol;Nebivolol
23 The Effect of Nasal Cannula During the First 2 Hours Postoperative in Patient Undergoing Thoracotomy Completed NCT01725464 Phase 4
24 Effect of Dutasteride on HIF-1alpha and VEGF in the Prostate Completed NCT00880672 Phase 4 dutasteride
25 Influence of Cardiopulmonary Bypass, and Sevoflurane or Propofol Anesthesia, on Tissue Oxygen Saturation. Completed NCT02593448 Phase 4
26 Safety Study of Analgesia After Craniotomy Surgery With End Tidal (ET) Carbon Dioxide (CO2) Monitoring Completed NCT01327677 Phase 4 Fentanyl;Fentanyl
27 Etomidate vs. Midazolam for Sedation During ERCP Completed NCT02027311 Phase 4 Etomidate;Midazolam;Meperidine
28 Randomized Clinical Trial of Propofol, 1:1 and 4:1 Combination of Propofol and Ketamine for Procedural Sedation Completed NCT01260662 Phase 4 Propofol;1:1 Propofol/Ketamine;4:1 Propofol/Ketamine
29 Treatment of Patients With the Obstructive Sleep Apnea Syndrome at Altitude Completed NCT00714740 Phase 4 acetazolamide
30 Cerebral Blood Flow and PETCO2 on Neuromuscular Function During Environmental Stress Completed NCT01830335 Phase 4 Indomethacin;Placebo
31 The Use of Statins for Myocardial Death Prevention Completed NCT00772564 Phase 4 Atorvastatin
32 Vasoactive Hormones During the Night in Patients With Obstructive Sleep Apnea Before and After Treatment With CPAP. Completed NCT00360659 Phase 4
33 Preventive Effect of the PRetreatment With Intravenous Nicorandil on Contrast-Induced Nephropathy in Patients With RenaL Dysfunction UndEergoing Coronary Angiography (PRINCIPLE Study) Completed NCT01103336 Phase 4 pretreatment with intravenous nicorandil vs. placebo before coronary angiography
34 Increased Renal Oxygenation and Angiotensin Converting Enzyme Inhibition Completed NCT01545479 Phase 4 captopril 25mg
35 Vasoactive Hormones During the Night in Patients With Obstructive Sleep Apnea and Healthy Controls. Completed NCT00291993 Phase 4
36 Ranibizumab in Patients With Branch Retinal Vein Occlusion Completed NCT01027481 Phase 4 Lucentis
37 Efficacy Study of Riociguat and Its Effects on Exercise Performance and Pulmonary Artery Pressure at High Altitude Completed NCT02024386 Phase 4 Riociguat
38 To Evaluate the Effect of Chlorhexidine-benzidamine Administration Completed NCT03253497 Phase 4 Chlorobenzene Liquid
39 The Effects of Oral Dipyridamole Treatment on the Innate Immune Response During Human Endotoxemia Completed NCT01091571 Phase 4 Dipyridamole;Placebo
40 The Correlations Between Early Enteral Nutrition and Intra-abdominal Pressure in Severe Acute Pancreatitis Completed NCT01507766 Phase 4 early enteral nutrition;Delayed enteral nutrition
41 Erythropoietin in the Prevention of Acute Mountain Sickness Completed NCT01665781 Phase 4 Erythropoietin
42 Acute Effect of Pulmonary Desufflation on Cardiac Performance in COPD Patients Completed NCT01996124 Phase 4 Indacaterol Fumarate;Placebo
43 Nasal Budesonide in Children With Rhinitis and/or Mild Obstructive Sleep Apnea Syndrome Completed NCT00560586 Phase 4 Budesonide;placebo
44 Bispectral Index and Clinical Parameters Evaluation in Dental Procedures Completed NCT02671578 Phase 4 Nitrous Oxide
45 Investigating the Accuracy of the Home Glucose Monitors in Hypoglycemia Completed NCT01013402 Phase 4 Human insulin;Human Insulin
46 Propofol-Ketamine vs Remifentanyl-Ketamine for Sedation in Pediatric Patients Undergoing Colonoscopy Completed NCT02602743 Phase 4 Remifentanyl;Propofol;Ketamine
47 Optiflow® to Prevent Post-Extubation Hypoxemia afteR Abdominal Surgery (the OPERA Trial) Completed NCT01887015 Phase 4
48 Regimen of Alfentanil in Propofol Sedative Fibro-bronchoscopy Completed NCT01470170 Phase 4 Alfentanil;Normal saline;Propofol
49 Recruitment Maneuver After Intubation Completed NCT01014299 Phase 4
50 Inhaled Nitric Oxide by Oxygen Hood in Neonates Completed NCT00732537 Phase 4 inhaled Nitric Oxide;Oxygen (>90% by hood) - standard therapy

Search NIH Clinical Center for Anoxia

Genetic Tests for Anoxia

Anatomical Context for Anoxia

MalaCards organs/tissues related to Anoxia:

38
Brain, Lung, Kidney, Heart, Prostate, Liver, Endothelial

Publications for Anoxia

Articles related to Anoxia:

(show top 50) (show all 679)
# Title Authors Year
1
Mitochondrial responses to anoxia exposure in red eared sliders (Trachemys scripta). ( 29402754 )
2018
2
Capsaicin prevents mitochondrial damage, protects cardiomyocytes subjected to anoxia/reoxygenation injury mediated by 14-3-3I^/Bcl-2. ( 29175072 )
2018
3
Prazosin protects myocardial cells against anoxia-reoxygenation injury via the extracellular signala89regulated kinase signaling pathway. ( 29207167 )
2018
4
Reversible growth arrest of 3D tumor spheroids stored in oxygen absorber-induced anoxia. ( 29434901 )
2018
5
Dynamic regulation of six histone H3 lysine (K) methyltransferases in response to prolonged anoxia exposure in a freshwater turtle. ( 29382574 )
2018
6
Hormetic benefits of prior anoxia exposure in buffering anoxia stress in a soil-pupating insect. ( 29367272 )
2018
7
The role of the ATPase inhibitor factor 1 (IF<sub>1</sub>) in cancer cells adaptation to hypoxia and anoxia. ( 29097244 )
2018
8
Sodium pump alpha-2 subunit (ATP1A2) alleviates cardiomyocyte anoxia/reoxygenation injury via inhibition of endoplasmic reticulum stress-related apoptosis. ( 29394489 )
2018
9
Sex differences in somatic and sensory motor development after neonatal anoxia in Wistar rats. ( 28709915 )
2017
10
Capsaicin Protects Cardiomyocytes against Anoxia/Reoxygenation Injury via Preventing Mitochondrial Dysfunction Mediated by SIRT1. ( 29435095 )
2017
11
Promotion of anoxia-reoxygenation-induced inflammation and permeability enhancement by nicotinamide phosphoribosyltransferase-activated MAPK signaling in human umbilical vein endothelial cells. ( 29104667 )
2017
12
Surviving anoxia in marine sediments: The metabolic response of ubiquitous benthic foraminifera (Ammonia tepida). ( 28562648 )
2017
13
An Efficient and Reliable Assay for Investigating the Effects of Hypoxia/Anoxia on Drosophila. ( 28866769 )
2017
14
Extreme anoxia tolerance in crucian carp and goldfish through neofunctionalization of duplicated genes creating a new ethanol-producing pyruvate decarboxylase pathway. ( 28801642 )
2017
15
Early Hippocampal i-LTP and LOX-1 Overexpression Induced by Anoxia: A Potential Role in Neurodegeneration in NPC Mouse Model. ( 28678158 )
2017
16
Characterization of ion channels and O2 sensitivity in gill neuroepithelial cells of the anoxia-tolerant goldfish (Carassius auratus). ( 28904098 )
2017
17
VDAC1 deacetylation is involved in the protective effects of resveratrol against mitochondria-mediated apoptosis in cardiomyocytes subjected to anoxia/reoxygenation injury. ( 28826100 )
2017
18
The role of MEF2 transcription factors in dehydration and anoxia survival in<i>Rana sylvatica</i>skeletal muscle. ( 29134152 )
2017
19
The effects of pH and Pi on tension and Ca(2+) sensitivity of ventricular myofilaments from the anoxia-tolerant painted turtle. ( 28939564 )
2017
20
GATA1 activated lncRNA (Galont) promotes anoxia/reoxygenation-induced autophagy and cell death in cardiomyocytes by sponging miR-338. ( 29247537 )
2017
21
I^-Aminobutyric Acid (GABA) Accumulation in Tea (Camellia sinensis L.) through the GABA Shunt and Polyamine Degradation Pathways under Anoxia. ( 28355482 )
2017
22
Re-oxygenation after anoxia induces brain cell death and memory loss in the anoxia-tolerant crucian carp. ( 29093186 )
2017
23
Tempol (4 hydroxy-tempo) inhibits anoxia-induced progression of mitochondrial dysfunction and associated neurobehavioral impairment in neonatal rats. ( 28320189 )
2017
24
Effects of erythropoietin on astrocytes and brain endothelial cells in primary culture during anoxia depend on simultaneous signaling by other cytokines and on duration of anoxia. ( 29180303 )
2017
25
Activation of hypoxia-inducible factor-1I+ in rat brain after perinatal anoxia: role of body temperature. ( 28974122 )
2017
26
Effect of Calcium-sensing Receptor on the Apoptosis of Rat Spinal Cord Neurons in Anoxia/Reoxygenation Injury and Its Significance. ( 29125103 )
2017
27
Exploration of low temperature microRNA function in an anoxia tolerant vertebrate ectotherm, the red eared slider turtle (Trachemys scripta elegans). ( 28689715 )
2017
28
Behavioural responses of naked mole rats to acute hypoxia and anoxia. ( 29263131 )
2017
29
Sediment anoxia limits microbial-driven seagrass carbon remineralization under warming conditions. ( 28334391 )
2017
30
Editorial: Eukaryotic Microbes Store Nitrate for "Breathing" in Anoxia. ( 29375489 )
2017
31
Inter- and intraspecific variability in physiological traits and post-anoxia recovery of photosynthetic efficiency in grasses under oxygen deprivation. ( 28767128 )
2017
32
Expression of phytoglobin affects nitric oxide metabolism and energy state of barley plants exposed to anoxia. ( 29223334 )
2017
33
Ocean deoxygenation, the global phosphorus cycle and the possibility of human-caused large-scale ocean anoxia. ( 28784709 )
2017
34
Charcoal evidence that rising atmospheric oxygen terminated Early Jurassic ocean anoxia. ( 28497785 )
2017
35
AMP-activated protein kinase protects against anoxia in Drosophila melanogaster. ( 28916374 )
2017
36
Small noncoding RNA expression during extreme anoxia tolerance of annual killifish (Austrofundulus limnaeus) embryos. ( 28802262 )
2017
37
SYK protects cardiocytes against anoxia and hypoglycemia-induced injury in ischemic heart failure. ( 28869869 )
2017
38
Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat. ( 28428423 )
2017
39
Boosted Membrane Potential as Bioenergetic Response to Anoxia in Dinoroseobacter shibae. ( 28473821 )
2017
40
Mitochondrial DNA Sequence and Lack of Response to Anoxia in the Annual Killifish Austrofundulus limnaeus. ( 27630577 )
2016
41
Puerarin Attenuates Anoxia/Reoxygenation Injury Through Enhancing Bcl-2 Associated Athanogene 3 Expression, a Modulator of Apoptosis and Autophagy. ( 27011313 )
2016
42
Carbohydrate metabolism in germinating caryopses of Oryza sativa L. exposed to prolonged anoxia. ( 27289587 )
2016
43
Roles of catalase and glutathione peroxidase in the tolerance of a pulmonate gastropod to anoxia and reoxygenation. ( 27062029 )
2016
44
Morphine-induced delayed pre-conditioning against anoxia/reoxygenation injury in pulmonary artery endothelial cells: The role of mitochondrial KATP channels. ( 26648415 )
2016
45
MicroRNAa89451 protects against cardiomyocyte anoxia/reoxygenation injury by inhibiting high mobility groupA boxA 1 expression. ( 27121079 )
2016
46
Deferoxamine improves antioxidative protection in the brain of neonatal rats: The role of anoxia and body temperature. ( 27297770 )
2016
47
Neonatal anoxia leads to time dependent progression of mitochondrial linked apoptosis in rat cortex and associated long term sensorimotor deficits. ( 27184438 )
2016
48
Rehabilitation following cerebral anoxia: An assessment of 27 patients. ( 26735867 )
2016
49
Marine anoxia and delayed Earth system recovery after the end-Permian extinction. ( 26884155 )
2016
50
Anti-apoptotic response during anoxia and recovery in a freeze-tolerant wood frog (Rana sylvatica). ( 27042393 )
2016

Variations for Anoxia

Expression for Anoxia

Search GEO for disease gene expression data for Anoxia.

Pathways for Anoxia

GO Terms for Anoxia

Cellular components related to Anoxia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peroxisome GO:0005777 8.92 ACOX1 NOS2 SOD1 XDH

Biological processes related to Anoxia according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.84 ACOX1 NOS2 SOD1 XDH
2 response to drug GO:0042493 9.73 ICAM1 OXTR SOD1
3 negative regulation of gene expression GO:0010629 9.58 CTGF NOS2 XDH
4 response to peptide hormone GO:0043434 9.55 CTGF OXTR
5 lactation GO:0007595 9.52 OXTR XDH
6 ovarian follicle development GO:0001541 9.51 ICAM1 SOD1
7 reactive oxygen species metabolic process GO:0072593 9.49 CTGF SOD1
8 negative regulation of protein catabolic process GO:0042177 9.48 NOS2 SIRT2
9 response to amino acid GO:0043200 9.46 CTGF ICAM1
10 positive regulation of vasoconstriction GO:0045907 9.43 ICAM1 OXTR
11 cell aging GO:0007569 9.37 ICAM1 SOD1
12 response to organic cyclic compound GO:0014070 9.33 CTGF ICAM1 OXTR
13 superoxide metabolic process GO:0006801 9.32 NOS2 SOD1
14 response to copper ion GO:0046688 9.26 ICAM1 SOD1
15 response to anoxia GO:0034059 8.96 CTGF OXTR
16 response to amphetamine GO:0001975 8.8 ICAM1 OXTR SOD1

Molecular functions related to Anoxia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 9.26 ACOX1 NOS2 SOD1 XDH
2 flavin adenine dinucleotide binding GO:0050660 8.8 ACOX1 NOS2 XDH

Sources for Anoxia

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7 CNVD
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33 ICD10 via Orphanet
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41 MeSH
42 MESH via Orphanet
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65 SNOMED-CT via HPO
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