MCID: ANT013
MIFTS: 33

Anterior Spinal Artery Syndrome

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Anterior Spinal Artery Syndrome

MalaCards integrated aliases for Anterior Spinal Artery Syndrome:

Name: Anterior Spinal Artery Syndrome 12 42 14 69
Anterior Spinal Artery Occlusion Syndrome 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6712
MeSH 42 D020759
SNOMED-CT 64 2972007
UMLS 69 C0221069

Summaries for Anterior Spinal Artery Syndrome

MalaCards based summary : Anterior Spinal Artery Syndrome, also known as anterior spinal artery occlusion syndrome, is related to coccidioidomycosis and paraplegia. An important gene associated with Anterior Spinal Artery Syndrome is SRP72 (Signal Recognition Particle 72), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Complement and coagulation cascades. The drugs Fibrinolytic Agents and Tissue Plasminogen Activator have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, medulla oblongata and brain, and related phenotypes are hematopoietic system and reproductive system

Wikipedia : 72 Anterior spinal artery syndrome (also known as \"anterior spinal cord syndrome\") is a medical condition... more...

Related Diseases for Anterior Spinal Artery Syndrome

Diseases related to Anterior Spinal Artery Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 106)
id Related Disease Score Top Affiliating Genes
1 coccidioidomycosis 30.3 F2 PLG
2 paraplegia 29.5 ADAMTS1 KANTR PLG TCHH
3 brain stem glioma 10.6 F2 PLG
4 internal auditory canal meningioma 10.5 MBP PLG
5 colon leiomyoma 10.5 KANTR PLG
6 silent myocardial infarction 10.5 KANTR PLG
7 hypoactive sexual desire disorder 10.5 KANTR PLG
8 posterolateral myocardial infarction 10.5 KANTR PLG
9 taylor's syndrome 10.5 F2 KANTR
10 vaginal carcinosarcoma 10.4 KANTR PLG
11 syncope 10.4 F2 SERPINC1
12 fragile x syndrome type 2 10.4 F2 SERPINC1
13 superior limbic keratoconjunctivitis 10.4 F2 SERPINC1
14 fungal meningitis 10.4 F2 KANTR
15 follicular adenoma 10.4 F2 SERPINC1
16 localized chondrosarcoma 10.4 KANTR PLG
17 testicular gonadoblastoma 10.4 F2 SERPINC1
18 collagenous colitis 10.4 F2 SERPINC1
19 hiv-1 10.4 F2 SERPINC1
20 glutathioninuria 10.4 F2 SERPINC1
21 pilomyxoid astrocytoma 10.4 F2 SERPINC1
22 lymphatic system cancer 10.4 F2 SERPINC1
23 rheumatoid lung disease 10.4 F2 SERPINC1
24 anterior cerebral artery infarction 10.4 KANTR PLG
25 angelucci's syndrome 10.4 F2 SERPINC1
26 lethal congenital contracture syndrome 10.4 F2 SERPINC1
27 transmitted_by 10.4 MBP TCHH
28 essential thrombocythemia 10.4 F2 SERPINC1
29 spinal cord lipoma 10.4 F2 SERPINC1
30 intestinal pseudo-obstruction 10.4 F2 SERPINC1
31 status asthmaticus 10.3 KANTR PLG
32 congenital syphilis 10.3 F2 SERPINC1
33 neuroaxonal dystrophy 10.3 F2 SERPINC1
34 urethritis 10.3 KANTR MBP
35 childhood brain stem glioma 10.3 F2 SERPINC1
36 cellular schwannoma 10.3 ADAMTS1 MBP
37 fuchs' endothelial dystrophy 10.3 KANTR MBP
38 adenosquamous bile duct carcinoma 10.3 KANTR MBP
39 parasitic helminthiasis infectious disease 10.3 PLG SERPINC1
40 angular blepharoconjunctivitis 10.3 F2 SERPINC1
41 hepadnavirus infection 10.3 F2 SERPINC1
42 dysgammaglobulinemia 10.3 F2 SERPINC1
43 dyskeratosis congenita autosomal recessive 10.3 F2 SERPINC1
44 mixed cell adenoma 10.3 KANTR MBP
45 inferior myocardial infarction 10.3 KANTR SERPINC1
46 rocky mountain spotted fever 10.3 KANTR SERPINC1
47 ulcerative stomatitis 10.3 F2 SERPINC1
48 haemophilus meningitis 10.2 PLG SERPINC1
49 3mc syndrome 10.2 KANTR MBP
50 blepharoconjunctivitis 10.2 F2 SERPINC1

Graphical network of the top 20 diseases related to Anterior Spinal Artery Syndrome:



Diseases related to Anterior Spinal Artery Syndrome

Symptoms & Phenotypes for Anterior Spinal Artery Syndrome

MGI Mouse Phenotypes related to Anterior Spinal Artery Syndrome:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.5 CCL1 F2 HSPB1 MBP PLG SDC1
2 reproductive system MP:0005389 9.1 ADAMTS1 F2 MBP PLG SDC1 SERPINC1

Drugs & Therapeutics for Anterior Spinal Artery Syndrome

Drugs for Anterior Spinal Artery Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Fibrinolytic Agents Phase 2
2 Tissue Plasminogen Activator Phase 2
3 Plasminogen Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Thrombolysis in Ischemic Spinal Cord Stroke Active, not recruiting NCT02242084 Phase 2 Intravenuse Alteplase

Search NIH Clinical Center for Anterior Spinal Artery Syndrome

Cochrane evidence based reviews: anterior spinal artery syndrome

Genetic Tests for Anterior Spinal Artery Syndrome

Anatomical Context for Anterior Spinal Artery Syndrome

MalaCards organs/tissues related to Anterior Spinal Artery Syndrome:

39
Spinal Cord, Medulla Oblongata, Brain, Eye

Publications for Anterior Spinal Artery Syndrome

Articles related to Anterior Spinal Artery Syndrome:

(show top 50) (show all 91)
id Title Authors Year
1
Coronary angiography as a rare cause for incomplete anterior spinal artery syndrome. ( 28229242 )
2017
2
Anterior spinal artery syndrome after double valve replacement and coronary artery bypass surgery. ( 28469882 )
2017
3
Anterior Spinal Artery Syndrome Following Coronary Artery Bypass Grafting: a Case Report. ( 28492795 )
2017
4
Anterior spinal artery syndrome after spinal anaesthesia for caesarean delivery with normal lumbar and thoracic magnetic resonance imaging. ( 27184089 )
2016
5
Poster 431 Anterior Spinal Artery Syndrome Caused by Traumatic Disk Herniation: A Case Report. ( 27673181 )
2016
6
Mechanisms and prevention of anterior spinal artery syndrome following abdominal aortic surgery. ( 25757179 )
2015
7
Systemic thrombolysis in anterior spinal artery syndrome: what has to be considered? ( 26386968 )
2015
8
"Owl eye sign": Anterior spinal artery syndrome. ( 26053834 )
2015
9
Anterior spinal artery syndrome: reversible paraplegia after minimally invasive spine surgery. ( 25210639 )
2014
10
Anterior spinal artery syndrome in a patient with vasospasm secondary to a ruptured cervical dural arteriovenous fistula. ( 22211300 )
2014
11
Images in anesthesiology: reversible anterior spinal artery syndrome during celiac plexus block. ( 22710956 )
2013
12
Anterior spinal artery syndrome presenting as cervical myelopathy in a patient with subclavian steal syndrome. ( 24195022 )
2013
13
Thoracic Disc Herniation leads to Anterior Spinal Artery Syndrome. Demonstrated by Diffusion.Weighted Magnetic Resonance Imaging (DWI): A Case Report and Literature Review. ( 24252234 )
2013
14
Delayed onset of anterior spinal artery syndrome after repair of aortic coarctation. ( 22858787 )
2012
15
Thrombolysis in anterior spinal artery syndrome. ( 22962400 )
2012
16
Anterior spinal artery syndrome after percutaneous vertebroplasty. ( 21835701 )
2011
17
Anterior spinal artery syndrome in a 13-year-old boy 8 days after taekwondo-fight: vascular obliteration due to vessel lesion or thrombophilia? ( 21509713 )
2011
18
Anterior spinal artery syndrome: a rare complication of head and neck surgery. ( 20193101 )
2010
19
Anterior spinal artery syndrome following vertebroplasty: a case report. ( 20110843 )
2010
20
Neurological symptoms after a provocative dive: spinal DCS or anterior spinal artery syndrome? ( 19817244 )
2009
21
Anterior spinal artery syndrome in a girl with Down syndrome: case report and literature review. ( 19810637 )
2009
22
Subclavian artery stenosis causing transient bilateral brachial diplegia: an unusual cause of anterior spinal artery syndrome. ( 18764753 )
2008
23
Anterior spinal artery syndrome complicating massive paravertebral abscess. ( 18274861 )
2008
24
Anterior spinal artery syndrome after abdominal stabbing and resuscitative thoracotomy. ( 17297346 )
2007
25
Sudden paraplegia due to an anterior spinal artery syndrome during the course of Staphylococcus aureus septicemia. ( 17675832 )
2007
26
Neurophysiological findings in a case of cervical anterior spinal artery syndrome: compound muscle action potentials, a marker for prognosis. ( 16718293 )
2006
27
Anterior spinal artery syndrome in a 16-year-old male. ( 16972534 )
2006
28
Anterior spinal artery syndrome after minimally invasive direct coronary artery bypass grafting under general combined epidural anesthesia. ( 15875563 )
2005
29
Anterior spinal artery syndrome in two children with genetic thrombotic disorders. ( 15832907 )
2005
30
Post-traumatic cervical kyphosis with surgical correction complicated by temporary anterior spinal artery syndrome. ( 15749431 )
2005
31
Anterior spinal artery syndrome after thoracic surgery. ( 16398981 )
2005
32
Delayed anterior spinal artery syndrome following posterior scoliosis correction. ( 15937672 )
2005
33
Anterior spinal artery syndrome complicating aortic dissecting aneurysm: case report. ( 15715137 )
2004
34
Anterior spinal artery syndrome following periradicular cervical nerve root therapy. ( 14991362 )
2004
35
Anterior spinal artery syndrome complicated by the ondine curse. ( 14676058 )
2003
36
Anterior spinal artery syndrome after peripheral angiography of the lower limbs. ( 12883547 )
2003
37
Anterior spinal artery syndrome after elective coronary artery bypass grafting. ( 12078809 )
2002
38
Anterior spinal artery syndrome after infrarenal abdominal aortic surgery. ( 12483181 )
2002
39
Comment on 'A cervical anterior spinal artery syndrome after diagnostic blockade of the right C6-nerve root', PJAM Brouwers et al., PAIN 91 (2001) 397-399. ( 11932079 )
2002
40
Anterior spinal artery syndrome: the diagnostic value of electromyography (EMG). ( 12529804 )
2002
41
Bilateral vocal fold paralysis and adhesion in anterior spinal artery syndrome. ( 12184587 )
2002
42
Anterior spinal artery syndrome after total spondylectomy of T10, T11, and T12. ( 12461371 )
2002
43
Anterior spinal artery syndrome after aortic surgery in a child. ( 11377109 )
2001
44
A cervical anterior spinal artery syndrome after diagnostic blockade of the right C6-nerve root. ( 11275398 )
2001
45
Anterior spinal artery syndrome following total hip arthroplasty under epidural anaesthesia. ( 11261915 )
2001
46
Anterior spinal artery syndrome in an adolescent with protein S deficiency. ( 11292220 )
2001
47
Anterior spinal artery syndrome masked by epidural analgesia. ( 10969382 )
2000
48
Thoracic disc herniation presenting with transient anterior spinal artery syndrome. A case report. ( 20667212 )
2000
49
Anterior spinal artery syndrome associated with severe stenosis of the vertebral artery. ( 9726482 )
1998
50
MRI of spinal cord and vertebral body infarction in the anterior spinal artery syndrome. ( 8692431 )
1996

Variations for Anterior Spinal Artery Syndrome

Expression for Anterior Spinal Artery Syndrome

Search GEO for disease gene expression data for Anterior Spinal Artery Syndrome.

Pathways for Anterior Spinal Artery Syndrome

GO Terms for Anterior Spinal Artery Syndrome

Cellular components related to Anterior Spinal Artery Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 blood microparticle GO:0072562 8.8 F2 PLG SERPINC1

Biological processes related to Anterior Spinal Artery Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.54 F2 PLG SERPINC1
2 blood coagulation GO:0007596 9.5 F2 PLG SERPINC1
3 regulation of blood coagulation GO:0030193 9.26 F2 SERPINC1
4 fibrinolysis GO:0042730 9.16 F2 PLG
5 negative regulation of fibrinolysis GO:0051918 8.96 F2 PLG
6 hemostasis GO:0007599 8.8 F2 PLG SERPINC1

Molecular functions related to Anterior Spinal Artery Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 heparin binding GO:0008201 8.8 ADAMTS1 F2 SERPINC1

Sources for Anterior Spinal Artery Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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