ASP
MCID: ANT011
MIFTS: 59

Antisocial Personality Disorder (ASP) malady

Rare diseases, Mental diseases categories

Summaries for Antisocial Personality Disorder

About this section
Sources:
9Disease Ontology, 66Wikipedia, 34MalaCards
See all sources

Fully expand this MalaCard

Download this MalaCard
Disease Ontology:9 A personality disorder that involves a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood.

MalaCards: Antisocial Personality Disorder, also known as psychopathic personality disorder, is related to personality disorder and substance abuse. An important gene associated with Antisocial Personality Disorder is HTR1B (5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled), and among its related pathways are Biogenic Amine Synthesis and Monoamine Transport. The compounds p-chloroamphetamine and minaprine have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and testes, and related mouse phenotypes are taste/olfaction and muscle.

Wikipedia:66 Antisocial (or dissocial) personality disorder is characterized by a pervasive pattern of disregard for,... more...

Aliases & Classifications for Antisocial Personality Disorder

About this section
Sources:
9Disease Ontology, 44NIH Rare Diseases, 11DISEASES, 46Novoseek, 63UMLS, 28ICD9CM, 59SNOMED-CT, 36MeSH, 26ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Mental diseases


Aliases & Descriptions:

antisocial personality disorder 9 44 11 46 63
psychopathic personality disorder 9
dissocial personality disorder 9
psychopathic personality 9
sociopathic personality 9
psychopath.personality 9
asocial personality 9
asp 44


External Ids:

Disease Ontology9 DOID:10939
ICD9CM28 301.7
MeSH36 D000987
ICD1026 F60.2

Related Diseases for Antisocial Personality Disorder

About this section
Sources:
18GeneCards, 19GeneDecks
See all sources

Diseases related to Antisocial Personality Disorder via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 79)
idRelated DiseaseScoreTop Affiliating Genes
1personality disorder32.1SLC6A4, SLC6A3, DRD2, MAOB, MAOA, HTR1B
2substance abuse31.3ALDH2, DRD2, SLC6A4, SLC6A3
3schizophrenia31.3HTR2A, COMT
4conduct disorder31.2TTF2, COMT, MAOA, DRD2, SLC6A4, SLC6A3
5cocaine dependence31.1SLC6A4, SLC6A3, DRD2
6substance dependence31.0DRD2, SLC6A4, SLC6A3, COMT
7anxiety disorder30.9SLC6A4, MAOA
8heroin dependence30.9ANKK1, DRD2
9alcohol dependence30.9ANKK1, HTR2A, HTR1B, MAOA, ALDH2, DRD2
10borderline personality disorder30.8MAOA, HTR1B, SLC6A4, TTF2
11pathological gambling30.7SLC6A3, DRD2
12alexithymia30.5ANKK1
13cocaine abuse30.4DRD2, SLC6A3, SLC6A4
14bipolar disorder30.4MAOA, SLC6A4, HTR2A
15drug dependence30.4DRD2, SLC6A4, SLC6A3, MAOA
16bulimia nervosa30.3MAOA, COMT, HTR1B, HTR2A, SLC6A4
17attention deficit hyperactivity disorder30.3TTF2, HTR2A, SLC6A3, SLC6A4, DRD2, MAOB
18alcohol abuse30.3SLC6A3, SLC6A4, DRD2, COMT, ALDH2
19dementia30.2ALDH2, HTR2A, SLC6A3, TTF2, COMT, MAOA
20sexual sadism10.4
21somatization disorder10.4
22histrionic personality disorder10.2
23impulse control disorder10.2
24mental retardation10.2
25hiv-110.2
26blindness10.2
27oppositional defiant disorder10.1SLC6A3
28melancholia10.1MAOA
29premature ejaculation10.1SLC6A4
30alcoholic psychosis10.1SLC6A4
31intermittent explosive disorder10.1HTR1B
32intellectual disability10.1
33neuroleptic malignant syndrome10.1DRD2
34endogenous depression10.1MAOA
35pervasive developmental disorder10.1SLC6A4
36serotonin syndrome10.1MAOA, HTR2A
37asperger syndrome10.1SLC6A4
38seasonal affective disorder10.1SLC6A4, HTR2A
39dysthymic disorder10.1HTR2A, MAOA
40striatonigral degeneration10.1DRD2, SLC6A3
41paranoid schizophrenia10.1COMT
42lesch-nyhan syndrome10.1SLC6A3, MAOA
43progressive supranuclear palsy10.1SLC6A3, DRD2
44portal hypertension10.1MAOA, HTR2A
45drug addiction10.1DRD2, SLC6A3
46chronic fatigue syndrome10.1SLC6A4, MAOA
47generalized anxiety disorder10.1SLC6A4, MAOA, HTR2A
48pure autonomic failure10.1MAOB, MAOA
49nicotine dependence10.1SLC6A4, DRD2, ANKK1
50central nervous system disease10.1SLC6A3, SLC6A4, HTR2A

Graphical network of the top 20 diseases related to Antisocial Personality Disorder:



Diseases related to antisocial personality disorder

Symptoms for Antisocial Personality Disorder

About this section

Drugs & Therapeutics for Antisocial Personality Disorder

About this section
Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Antisocial Personality Disorder

Drug clinical trials:

Search ClinicalTrials for Antisocial Personality Disorder

Search NIH Clinical Center for Antisocial Personality Disorder

Search CenterWatch for Antisocial Personality Disorder

Genetic Tests for Antisocial Personality Disorder

About this section

Anatomical Context for Antisocial Personality Disorder

About this section
Sources:
34MalaCards
See all sources

MalaCards organs/tissues related to Antisocial Personality Disorder:

34
Brain, Eye, Testes, Cortex, Prefrontal cortex

Animal Models for Antisocial Personality Disorder or affiliated genes

About this section
Sources:
38MGI
See all sources

MGI Mouse Phenotypes related to Antisocial Personality Disorder:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053949.1SLC6A3, DRD2, SNAP25
2MP:00053698.3DRD2, SNAP25, HTR2A, SLC6A3, HTR1B, SLC6A4
3MP:00053798.1SLC6A4, SNAP25, HTR1B, HTR2A, PRL, DRD2
4MP:00053907.8HTR1B, SLC6A3, DRD2, ALDH2, SNAP25, HTR2A
5MP:00107717.8SNAP25, SLC6A3, SLC6A4, DRD2, ALDH2, PRL
6MP:00053897.7SLC6A3, PRL, DRD2, ALDH2, COMT, HTR1B
7MP:00036316.4MAOB, MAOA, GABRA6, DRD2, GABRB2, COMT
8MP:00053766.4SNAP25, PRL, SLC6A3, COMT, MAOA, MAOB
9MP:00053865.9SLC6A4, PRL, HTR1B, SLC6A3, SNAP25, COMT

Publications for Antisocial Personality Disorder

About this section
Sources:
53PubMed
See all sources

Articles related to Antisocial Personality Disorder:

(show top 50)    (show all 309)
idTitleAuthorsYear
1
Comorbidity of social anxiety disorder and antisocial personality disorder in the National Epidemiological Survey on Alcohol and Related Conditions (NESARC). (24384071)
2013
2
Antisocial Personality Disorder Subscale (Chinese Version) of the Structured Clinical Interview for the DSM-IV Axis II disorders: validation study in Cantonese-speaking Hong Kong Chinese. (23807628)
2013
3
The role of fearless dominance in differentiating psychopathy from antisocial personality disorder: comment on Marcus, Fulton, and Edens. (23339316)
2013
4
Reduced cortical call to arms differentiates psychopathy from antisocial personality disorder. (22850322)
2013
5
The social-cognitive basis of borderline and antisocial personality disorder: introduction. (23342953)
2013
6
The relationship between adult reactive and proactive aggression, hostile interpretation bias, and antisocial personality disorder. (23342957)
2013
7
The association of 5-HTR2A-1438A/G, COMTVal158Met, MAOA-LPR, DATVNTR and 5-HTTVNTR gene polymorphisms and antisocial personality disorder in male heroin-dependent Chinese subjects. (22138326)
2012
8
White matter microstructural abnormalities in the frontal lobe of adults with antisocial personality disorder. (21777912)
2012
9
Borderline but not antisocial personality disorder symptoms are related to self-reported partner aggression in late middle-age. (22732005)
2012
10
Electroencephalographic abnormalities in antisocial personality disorder. (22152445)
2012
11
Childhood Maltreatment and Prospectively Observed Quality of Early Care as Predictors of Antisocial Personality Disorder Features. (22754051)
2012
12
Crack users show high rates of antisocial personality disorder, engagement in illegal activities and other psychosocial problems. (22691017)
2012
13
Diagnosis of antisocial personality disorder and criminal responsibility. (21903271)
2011
14
Gene environment interactions with a novel variable Monoamine Oxidase A transcriptional enhancer are associated with antisocial personality disorder. (21554924)
2011
15
Diagnosis and subtypes of adolescent antisocial personality disorder. (20420477)
2010
16
Incremental effect for antisocial personality disorder genetic risk combining 5-HTTLPR and 5-HTTVNTR polymorphisms. (20363030)
2010
17
Borderline Personality Disorder, Bulimia Nervosa, Antisocial Personality Disorder, ADHD, Substance Use: Common Threads, Common Treatment Needs, and the Nature of Impulsivity. (21253443)
2010
18
MAOA-uVNTR polymorphism may modify the protective effect of ALDH2 gene against alcohol dependence in antisocial personality disorder. (19302089)
2009
19
Frontal brain dysfunction in alcoholism with and without antisocial personality disorder. (19557141)
2009
20
A treatment guideline for people with antisocial personality disorder: overcoming attitudinal barriers and evidential limitations. (19343700)
2009
21
Qualitative and quantitative EEG abnormalities in violent offenders with antisocial personality disorder. (19134998)
2009
22
The relationship between distress tolerance and antisocial personality disorder among male inner-city treatment seeking substance users. (18834298)
2008
23
Correspondence between self-report and interview-based assessments of antisocial personality disorder. (18315398)
2008
24
Increased anxiety and other similarities in temperament of alcoholics with and without antisocial personality disorder across three diverse populations. (17452294)
2007
25
Serotonergic function in children with attention-deficit hyperactivity disorder: relationship to later antisocial personality disorder. (17470955)
2007
26
Conduct disorder and antisocial personality disorder in persons with severe psychiatric and substance use disorders. (16574783)
2006
27
Psychopathy/antisocial personality disorder conundrum. (16756576)
2006
28
Antisocial personality disorder in Turkish substance dependent patients and its relationship with anxiety, depression and a history of childhood abuse. (16910384)
2006
29
Etiology of antisocial personality disorder: benefits for society from an evolutionary standpoint. (16006050)
2005
30
Borderline personality disorder, antisocial personality disorder and risk-taking among heroin users: findings from the Australian Treatment Outcome Study (ATOS). (15072810)
2004
31
Mate similarity for substance dependence and antisocial personality disorder symptoms among parents of patients and controls. (15276222)
2004
32
Neither antisocial personality disorder nor antisocial alcoholism is associated with the MAO-A gene in Han Chinese males. (12824808)
2003
33
Increased impulsivity in cocaine dependent subjects independent of antisocial personality disorder and aggression. (12167556)
2002
34
Evidence in an international sample of alcohol-dependent subjects of subgroups with specific symptom patterns of antisocial personality disorder. (12170119)
2002
35
Diagnosing antisocial personality disorder among substance abusers: the scid versus the MCMI-II. (11727884)
2001
36
Risk factors in childhood that lead to the development of conduct disorder and antisocial personality disorder. (11196010)
2001
37
Effective treatment of aggression and impulsivity in antisocial personality disorder with risperidone. (11285097)
2001
38
Conduct disorder, antisocial personality disorder and substance use disorders in schizophrenia and major affective disorders. (10091967)
1999
39
Therapeutic community treatment for substance abusers with antisocial personality disorder. (10435260)
1999
40
Gender differences in the relationship of antisocial personality disorder criteria to Psychopathy Checklist-Revised scores. (9573521)
1998
41
Antisocial Personality Disorder and depression in relation to alcoholism: a community-based sample. (9500310)
1998
42
Gender and drug differences in antisocial personality disorder. (9169384)
1997
43
An ethical framework for understanding patients with antisocial personality disorder who develop dementia: diagnosing and managing disorders of autonomy. (11656997)
1997
44
Death rates in 71 men with antisocial personality disorder. A comparison with general population mortality. (8742541)
1996
45
A 16- to 45-year follow-up of 71 men with antisocial personality disorder. (7758299)
1995
46
Antisocial personality disorder as a prognostic factor for pharmacotherapy of cocaine dependence. (8082553)
1994
47
Drinking outcomes of alcohol abusers diagnosed as antisocial personality disorder. (7978086)
1994
48
Personality and disinhibitory psychopathology: alcoholism and antisocial personality disorder. (8040486)
1994
49
A case of pseudologia fantastica with antisocial personality disorder. (1742719)
1991
50
The antisocial personality disorder diagnosis. (2386266)
1990

Variations for Antisocial Personality Disorder

About this section

Expression for genes affiliated with Antisocial Personality Disorder

About this section
Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Antisocial Personality Disorder

Search GEO for disease gene expression data for Antisocial Personality Disorder.

Pathways for genes affiliated with Antisocial Personality Disorder

About this section
Sources:
51PathCards, 39NCBI BioSystems Database, 56Reactome, 52PharmGKB, 61Thomson Reuters, 31KEGG
See all sources

Pathways related to Antisocial Personality Disorder according to GeneCards/GeneDecks:

(show all 23)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
catecholamine biosynthesis39
9.8MAOA, COMT
2
Show member pathways
Serotonin Transporter Activity39
9.8SLC6A3, SLC6A4, MAOA
3
Show member pathways
9.7HTR2A, HTR1B, DRD2
4
Show member pathways
9.6GABRB2, GABRA6
5
Show member pathways
tryptophan degradation X (mammalian, via tryptamine)39
2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA39
tryptophan degradation39
glutaryl-CoA degradation39
serotonin degradation39
NAD de novo biosynthesis39
superpathway of melatonin degradation39
tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde39
tryptophan utilization I39
melatonin degradation I39
9.5ALDH2, MAOB, MAOA
6
Show member pathways
9.5ALDH2, MAOB, MAOA
7
Show member pathways
citrulline-nitric oxide cycle39
arginine degradation I (arginase pathway)39
proline degradation39
glutamine degradation I39
proline biosynthesis I39
superpathway of citrulline metabolism39
proline biosynthesis II (from arginine)39
citrulline biosynthesis39
arginine degradation VI (arginase 2 pathway)39
Urea cycle and metabolism of amino groups39
asparagine biosynthesis I39
4-hydroxyproline degradation I39
citrulline degradation39
9.5MAOA, MAOB, ALDH2
8
Show member pathways
9.5ALDH2, MAOB, MAOA
9
Show member pathways
histamine biosynthesis39
9.5MAOA, MAOB, ALDH2
109.5ALDH2, MAOB, MAOA
119.5HTR2A, HTR1B, MAOA, SLC6A4
12
Show member pathways
9.5ALDH2, MAOA, COMT
139.5COMT, MAOA, MAOB
149.5COMT, MAOA, MAOB
159.5MAOB, MAOA, COMT
16
Show member pathways
9.4SLC6A3, DRD2, MAOB, MAOA
17
Show member pathways
phenylalanine utilization39
noradrenaline and adrenaline degradation39
phenylalanine degradation IV39
9.1COMT, MAOA, MAOB, ALDH2
18
Show member pathways
9.1COMT, MAOA, MAOB, ALDH2
19
Show member pathways
8.9PRL, MAOA, MAOB, DRD2, SLC6A3
208.9HTR2A, SNAP25, MAOA, SLC6A4
21
Show member pathways
8.4PRL, HTR2A, HTR1B, DRD2, GABRA6, GABRB2
22
Show member pathways
7.6SNAP25, COMT, MAOA, ALDH2, GABRA6, GABRB2
23
Show member pathways
7.4SLC6A3, HTR2A, HTR1B, COMT, MAOA, MAOB

Compounds for genes affiliated with Antisocial Personality Disorder

About this section
Sources:
46Novoseek, 12DrugBank, 25HMDB, 30IUPHAR, 52PharmGKB, 3BitterDB, 62Tocris Bioscience
See all sources

Compounds related to Antisocial Personality Disorder according to GeneCards/GeneDecks:

(show top 50)    (show all 305)
idCompoundScoreTop Affiliating Genes
1p-chloroamphetamine469.7MAOB, MAOA, SLC6A4, SLC6A3
2minaprine46 1210.7HTR2A, DRD2, MAOA, SLC6A4
3phentermine46 1210.7MAOB, SLC6A4, SLC6A3, MAOA
4d amphetamine469.5DRD2, SLC6A4, SLC6A3, MAOA, MAOB
5mcpp469.5HTR1B, HTR2A, PRL, SLC6A4
6Serotonin259.5MAOA, MAOB, HTR1B, HTR2A, SLC6A4
7pindolol46 30 1211.4PRL, SLC6A4, HTR1B, HTR2A
8fluvoxamine46 52 1211.4HTR2A, COMT, MAOA, SLC6A4, SLC6A3
9amoxapine30 46 1211.4HTR2A, PRL, SLC6A4, DRD2
10trimipramine46 52 1211.4DRD2, SLC6A3, SLC6A4, HTR2A, PRL
11amitriptyline46 30 52 1212.3SLC6A4, MAOB, MAOA, SLC6A3, HTR2A
12mdma469.3MAOB, SLC6A3, MAOA, PRL, SLC6A4
13tyramine46 30 2511.3SLC6A4, SLC6A3, COMT, MAOB, MAOA
14ropinirole46 1210.3HTR2A, HTR1B, COMT, MAOB, DRD2
15terguride46 3010.3DRD2, HTR1B, HTR2A, PRL
16clomipramine46 52 1211.2PRL, HTR1B, SLC6A3, HTR2A, MAOA, SLC6A4
17pergolide46 30 1211.2HTR2A, DRD2, COMT, PRL, HTR1B
18carbidopa46 3010.2COMT, PRL, MAOB, SLC6A3
19amphetamine46 52 1211.2SLC6A3, SLC6A4, MAOA, MAOB, DRD2
20venlafaxine46 52 25 1212.2HTR2A, GABRA6, HTR1B, COMT, SLC6A4, SLC6A3
21cabergoline46 30 1211.2HTR2A, DRD2, COMT, HTR1B, PRL
22quetiapine46 52 30 25 1213.2DRD2, HTR1B, SLC6A4, HTR2A, PRL, SLC6A3
23methylphenidate46 52 1211.1SLC6A3, DRD2, MAOB, MAOA, COMT, SLC6A4
24mhpg469.1MAOA, COMT, PRL, MAOB, SLC6A4
25homovanillic acid46 2510.1SLC6A4, PRL, COMT, MAOA, MAOB
26imipramine46 30 52 25 1213.1HTR2A, MAOA, MAOB, SLC6A4, SLC6A3
27methamphetamine46 52 1211.1SLC6A4, SLC6A3, DRD2, MAOB, MAOA, COMT
286-hydroxydopamine469.1DRD2, MAOA, SLC6A3, MAOB, COMT
29mptp469.1DRD2, SLC6A4, COMT, MAOB, SLC6A3, MAOA
30bupropion52 46 25 1212.0SLC6A4, MAOB, COMT, ANKK1, SLC6A3, DRD2
31pramipexole46 30 52 1212.0PRL, HTR2A, DRD2, SLC6A3, HTR1B, COMT
32citalopram46 52 25 1212.0SLC6A3, SLC6A4, MAOB, PRL, HTR2A, MAOA
33bromocriptine46 30 1211.0SLC6A3, DRD2, COMT, HTR1B, HTR2A, PRL
34ritanserin46 3010.0DRD2, HTR1B, HTR2A, PRL
35haloperidol46 52 30 3 1212.9HTR2A, SLC6A3, SLC6A4, DRD2, MAOB, PRL
36paroxetine46 52 30 1211.8HTR2A, SLC6A3, SLC6A4, MAOA, COMT, HTR1B
37levodopa46 129.7PRL, SLC6A3, DRD2, MAOB, MAOA, COMT
38apomorphine30 46 1210.7DRD2, MAOB, COMT, HTR1B, HTR2A, PRL
39maoa468.7SLC6A4, DRD2, MAOB, MAOA, HTR2A, HTR1B
40carbon468.6SLC6A3, COMT, TTF2, SLC6A4, MAOB, MAOA
41cocaine46 129.6HTR1B, SLC6A4, DRD2, MAOB, COMT, PRL
42fluoxetine46 52 30 1211.6PRL, HTR2A, HTR1B, MAOA, MAOB, DRD2
43nicotine46 30 52 1211.6TTF2, MAOB, MAOA, COMT, ANKK1, DRD2
44risperidone46 52 30 62 25 1213.5ANKK1, HTR2A, HTR1B, COMT, DRD2, SLC6A4
45olanzapine46 52 30 25 1212.5SLC6A3, SLC6A4, PRL, ANKK1, HTR2A, HTR1B
46clozapine46 30 52 1211.5SLC6A3, SLC6A4, DRD2, COMT, HTR1B, HTR2A
47gaba468.3GABRA6, MAOB, MAOA, SNAP25, SLC6A4, SLC6A3
485-hydroxytryptamine468.2HTR2A, PRL, SLC6A3, SLC6A4, DRD2, MAOB
49norepinephrine46 25 129.6DRD2, MAOB, SLC6A4, MAOA, SLC6A3, COMT
50dopamine46 30 25 1210.0COMT, MAOA, DRD2, MAOB, ALDH2, SLC6A4

GO Terms for genes affiliated with Antisocial Personality Disorder

About this section
Sources:
17Gene Ontology
See all sources

Cellular components related to Antisocial Personality Disorder according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1axonGO:0304249.7SLC6A3, DRD2, HTR2A
2integral component of plasma membraneGO:0058877.8SLC6A3, HTR2A, HTR1B, COL25A1, DRD2, GABRA6
3plasma membraneGO:0058866.3HTR2A, HTR1B, SNAP25, COMT, COL25A1, DRD2

Biological processes related to Antisocial Personality Disorder according to GeneCards/GeneDecks:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1monoamine transportGO:01584410.3SLC6A3, SLC6A4
2adenohypophysis developmentGO:02198410.2SLC6A3, DRD2
3regulation of dopamine secretionGO:01405910.2HTR1B, HTR2A
4G-protein coupled receptor internalizationGO:00203110.2DRD2, HTR1B
5negative regulation of serotonin secretionGO:01406310.2MAOB, HTR1B
6regulation of behaviorGO:05079510.2HTR1B, HTR2A
7response to iron ionGO:01003910.1DRD2, SLC6A3
8neurotransmitter catabolic processGO:04213510.1MAOA, COMT
9behavioral response to cocaineGO:04814810.1HTR2A, DRD2
10response to cocaineGO:04222010.1HTR1B, DRD2, SLC6A3
11prepulse inhibitionGO:06013410.1SLC6A3, DRD2
12vasoconstrictionGO:04231010.1HTR1B, SLC6A4
13negative regulation of synaptic transmission, glutamatergicGO:05196710.1DRD2, HTR1B, HTR2A
14dopamine catabolic processGO:04242010.0SLC6A3, MAOA, COMT
15temperature homeostasisGO:0016599.9HTR2A, DRD2
16release of sequestered calcium ion into cytosolGO:0512099.9DRD2, HTR2A
17response to ethanolGO:0454719.9HTR1B, MAOB, SLC6A3
18response to toxic substanceGO:0096369.9MAOB, DRD2, SLC6A4
19response to nicotineGO:0350949.7SLC6A3, DRD2
20neurotransmitter biosynthetic processGO:0421369.6COMT, MAOA, ALDH2, SLC6A3
21gamma-aminobutyric acid signaling pathwayGO:0072149.5GABRB2, GABRA6
22xenobiotic metabolic processGO:0068059.4ALDH2, MAOB, MAOA, COMT
23response to drugGO:0424939.0HTR2A, COMT, MAOB, DRD2, SLC6A4, SLC6A3
24synaptic transmissionGO:0072688.0SLC6A3, GABRB2, ALDH2, MAOA, COMT, SNAP25

Molecular functions related to Antisocial Personality Disorder according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1monoamine transmembrane transporter activityGO:00850410.1SLC6A3, SLC6A4
2serotonin bindingGO:05137810.0HTR2A, HTR1B
3primary amine oxidase activityGO:0081319.9MAOB, MAOA
4dopamine bindingGO:0352409.9SLC6A3, DRD2
5serotonin receptor activityGO:0049939.7HTR1B, HTR2A
6GABA-A receptor activityGO:0048909.6GABRB2, GABRA6
7drug bindingGO:0081449.6SLC6A3, DRD2, HTR1B, HTR2A

Products for genes affiliated with Antisocial Personality Disorder

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Antisocial Personality Disorder

About this section
4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet