MCID: ANT011
MIFTS: 40

Antisocial Personality Disorder malady

Mental diseases category

Aliases & Classifications for Antisocial Personality Disorder

About this section
Sources:
10Disease Ontology, 47Novoseek, 12DISEASES, 65UMLS, 36MeSH, 59SNOMED-CT, 29ICD9CM, 27ICD10
See all sources

Aliases & Descriptions for Antisocial Personality Disorder:

Name: Antisocial Personality Disorder 10 47 12 65 36
Psychopathic Personality Disorder 10
Dissocial Personality Disorder 10
Psychopathic Personality 10
 
Sociopathic Personality 10
Psychopath.personality 10
Asocial Personality 10


Classifications:



External Ids:

Disease Ontology10 DOID:10939
ICD9CM29 301.7
MeSH36 D000987
ICD1027 F60.2

Summaries for Antisocial Personality Disorder

About this section
Disease Ontology:10 A personality disorder that involves a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood.

MalaCards based summary: Antisocial Personality Disorder, also known as psychopathic personality disorder, is related to borderline personality disorder and substance dependence. An important gene associated with Antisocial Personality Disorder is MAOA (Monoamine Oxidase A), and among its related pathways are Selective Serotonin Reuptake Inhibitor Pathway, Pharmacodynamics and Enzymatic degradation of dopamine by COMT. Affiliated tissues include cortex, prefrontal cortex and brain, and related mouse phenotypes are integument and homeostasis/metabolism.

Wikipedia:68 Antisocial (or dissocial) personality disorder is characterized by a pervasive pattern of disregard for,... more...

Related Diseases for Antisocial Personality Disorder

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Diseases related to Antisocial Personality Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 91)
idRelated DiseaseScoreTop Affiliating Genes
1borderline personality disorder30.9MAOA, MAOB
2substance dependence30.5DRD2, MAOA, PRL, SLC6A3, SLC6A4
3schizophrenia30.4DRD2, MAOA, MAOB, PRL, SLC6A3, SLC6A4
4attention deficit-hyperactivity disorder30.0DRD2, MAOA, MAOB, SLC6A3, SLC6A4
5alcohol dependence29.5ALDH2, ANKK1, DRD2, MAOA, MAOB, PRL
6personality disorder11.5
7substance abuse10.9
8conduct disorder10.9
9cocaine dependence10.7
10heroin dependence10.6
11anxiety disorder10.6
12bipolar disorder10.4
13pathological gambling10.4
14somatization disorder10.4
15sexual sadism10.4
16postsurgical hypothyroidism10.2MAOA, SLC6A4
17phosphorus metabolism disease10.2MAOA, SLC6A4
18hiv-110.2
19alcohol abuse10.2
20generalized anxiety disorder10.2
21bulimia nervosa10.2
22histrionic personality disorder10.2
23alexithymia10.2
24cocaine abuse10.2
25dementia10.2
26drug dependence10.2
27impulse control disorder10.2
28familial glomangioma10.2MAOA, SLC6A4
29malignant renovascular hypertension10.2MAOA, SLC6A4
30pericardial tuberculosis10.2MAOA, SLC6A4
31sideroblastic anemia10.2PRL, SLC6A4
32spastic quadriplegia10.2MAOA, SLC6A4
33dental fluorosis10.2SLC6A3, SLC6A4
34chronic leukemia10.2MAOA, SLC6A4
35deafness and myopia10.2MAOA, PRL
36mesenchymal cell neoplasm10.2MAOA, SLC6A4
37frey syndrome10.2MAOA, MAOB
38endometrial adenocarcinoma10.2MAOA, SLC6A4
39histidinemia10.1PRL, SLC6A3
40purpura simplex10.1MAOA, MAOB
41secretory diarrhea10.1MAOB, SLC6A3
42exudative vitreoretinopathy 2, x-linked10.1MAOA, MAOB
43ainhum10.1DRD2, PRL
44pregerminal center chronic lymphocytic leukemia/small lymphocytic lymphoma10.1MAOA, PRL, SLC6A4
45clear cell adenoma10.1DRD2, PRL
46leech infestation10.1MAOA, PRL, SLC6A4
47nephrogenic adenoma of urinary bladder10.1DRD2, PRL
48intellectual disability10.1
49melanotic neuroectodermal tumor10.1DRD2, SLC6A4
50major depressive disorder and accelerated response to antidepressant drug treatment10.1MAOA, PRL, SLC6A4

Graphical network of the top 20 diseases related to Antisocial Personality Disorder:



Diseases related to antisocial personality disorder

Symptoms for Antisocial Personality Disorder

About this section

Drugs & Therapeutics for Antisocial Personality Disorder

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Drugs for Antisocial Personality Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Naratriptanapproved, investigationalPhase 414143388-64-1, 121679-13-84440
Synonyms:
121679-13-8
AC-5013
AC1L1I6A
Amerge
Amerge, Naramig,Naratriptan
BIDD:GT0312
C07792
CHEBI:7478
CHEMBL1278
CID4440
Colatan
D08255
DB00952
InChI=1/C17H25N3O2S/c1-18-23(21,22)10-7-13-3-4-17-15(11-13)16(12-19-17)14-5-8-20(2)9-6-14/h3-4,11-12,14,18-19H,5-10H2,1-2H
L000432
 
LS-83062
MolPort-005-932-823
N-Methyl-2-(3-(1-methylpiperiden-4-yl)indole-5-yl)ethanesulfonamide
N-Methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamide
N-methyl-2-(3-(1-methylpiperiden-4-yl)indole-5-yl)ethanesulfonamide
N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamide
N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide
NCGC00181786-01
Naramig
Naramig (TN)
Naratriptan
Naratriptan (INN)
Naratriptanum
S1488_Selleck
UNII-QX3KXL1ZA2
naratriptan
naratriptanum
2
SerotoninPhase 4285350-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
3Phase 2, Phase 3
4Omega 3 Fatty AcidNutraceuticalPhase 2, Phase 3890
5CoagulantsPhase 2983
6VasopressinsPhase 2159
7Arginine VasopressinPhase 2163
8arginineNutraceuticalPhase 2346
9
Dextroamphetamineapproved, illicit12251-64-95826
Synonyms:
(+)-(S)-Amphetamine
(+)-(S)-amphetamine
(+)-(s)-amphetamine
(+)-Amphetamine
(+)-Phenaminum
(+)-alpha-Methylphenethylamine
(+)-alpha-Methylphenylethylamine
(+)-alpha-methylphenethylamine
(+)-alpha-methylphenylethylamine
(+)-amphetamine
(+)-phenaminum
(+/-)-Benzedrine
(+/-)-Desoxynorephedrine
(+/-)-beta-Phenylisopropylamine
(2S)-(+)-Amphetamine
(2S)-1-phenylpropan-2-amine
(AlphaS)-alpha-methylbenzeneethanamine
(S)-(+)-Amphetamine
(S)-(+)-beta-Phenylisopropylamine
(S)-1-Phenyl-2-aminopropane
(S)-1-Phenyl-2-propanamine
(S)-1-Phenyl-2-propylamine
(S)-1-phenyl-2-aminopropane
(S)-1-phenyl-2-propylamine
(S)-Amphetamine
(S)-alpha-Methylbenzeneethanamine
(S)-alpha-Methylphenethylamine
(S)-alpha-Phenylethylamine
(S)-alpha-methylbenzeneethanamine
(S)-amphetamine
(alphaS)-alpha-methylbenzeneethanamine
(s)-(+)-amphetamine
(s)-(+)-beta-phenylisopropylamine
(s)-alpha-methylbenzeneethanamine
(s)-alpha-methylphenethylamine
(s)-alpha-phenylethylamine
(s)-amphetamine
1-Methyl-2-phenylethylamine
4-12-00-02587 (Beilstein Handbook Reference)
51-64-9
AC1L1L85
Amsustain
BRN 2205872
Benzedrine
Benzeneethanamine, alpha-methyl-, (aS)- (9CI)
C07884
CHEBI:4469
CHEMBL612
CID5826
D-(+)-Amphetamine
D-(+)-amphetamine
D-(S)-Amphetamine
D-(s)-amphetamine
D-1-Phenyl-2-aminopropan
D-1-Phenyl-2-aminopropane
D-2-Amino-1-phenylpropane
D-AM
D-Amphetamine
D-alpha-methylphenethylamine
D-am
D-amphetamine
D03740
DB00182
DB01576
DEA No. 1100
Dephadren
 
Desamfetamina
Desamfetamina [DCIT]
Desoxyn
Dexacaps
Dexadrine
Dexamfetamina
Dexamfetamina [INN-Spanish]
Dexamfetamina [inn-spanish]
Dexamfetamine
Dexamfetamine (INN)
Dexamfetaminum
Dexamfetaminum [INN-Latin]
Dexamfetaminum [inn-latin]
Dexamphetamine
Dexamphetaminum
Dexamphetaminum [INN-Latin]
Dexamphetaminum [inn-latin]
Dexanfetamina
Dexanfetamina [INN-Spanish]
Dexanfetamina [inn-spanish]
Dexedrine
Dexedrine Spansule
Dexidrine
Dextro-Amphetamine Sulfate
Dextroamphetamine
Dextroamphetamine (USAN)
Dextroamphetamine Sulfate
Dextroamphetamine [USAN]
Dextroamphetamine resin complex
Dextroamphetamine sulfate
Dextrostat
EINECS 200-112-1
Fenylo-izopropylaminyl
HSDB 3055
Isoamycin
LS-103617
LS-187774
MolPort-004-285-839
NCGC00168247-01
NSC 73713
PDSP1_001511
PDSP2_001495
Phenethylamine, alpha-methyl-, (+)- (8CI)
Procentra
Propisamine
Psychedrine
Raphetamine
Rhinalator
S(+)-Amphetamine
S(+)-amphetamine
Simpatedrin
Sympamin
Sympamine
Sympatedrine
UNII-TZ47U051FI
Weckamine
Zenzedi
alpha-Methylphenethylamine, d-form
beta-phenyl-isopropylamine
d-1-Phenyl-2-aminopropan [German]
d-amphetamine
dexamphetamine
dextro-Amphetamine
dextroamphetamine
dl-1-Phenyl-2-aminopropane
dl-Amphetamine
dl-Benzedrine
10
Dopamineapproved281462-31-7, 51-61-6681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine Hcl
Dopamine Hydrochloride
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
 
KBio1_000780
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
11
Yohimbineapproved25146-48-58969
Synonyms:
(+)-Yohimbin
(+)-Yohimbine
(+)-yohimbine
(16alpha,17alpha)-17-Hydroxy-yohimban-16-carboxylic acid methyl ester
(16alpha,17alpha)-17-Hydroxyyohimban-16-carboxylic acid methyl ester
(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester
146-48-5
17-Hydroxy-yohimbane-16-carboxylic acid methyl ester
17-Hydroxyyohimban-16-carboxylic acid methyl ester
17alpha-Hydroxyyohimban-16alpha-carboxylic acid methyl ester
17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester
2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester
4-25-00-01237 (Beilstein Handbook Reference)
65-19-0
AC1L1S1D
APHRODINE
Actibine
Aphrodine
Aphrodyne
Aphrosol
BCBcMAP01_000032
BPBio1_000472
BRD-K35586044-001-02-6
BRD-K35586044-003-03-0
BRN 0097276
BSPBio_000428
BSPBio_001236
Baron-X
Benz[g]indolo[2,3-a]quinolizine, yohimban-16-carboxylic acid deriv.
Bio1_000455
Bio1_000944
Bio1_001433
Bio2_000458
Bio2_000938
C09256
CHEBI:10093
CHEMBL15245
CID8969
Corynine
D08685
DB01392
Dayto himbin
EINECS 205-672-0
HMS1362N17
HMS1792N17
HMS1990N17
HMS2089G19
I14-13374
IDI1_002213
 
InChI=1/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12?,15?,17?,18-,19+/m0/s
Johimbin
KBio2_000576
KBio2_003144
KBio2_005712
KBio3_001031
KBio3_001032
KBioGR_000576
KBioSS_000576
LS-162738
Lopac0_001210
MLS000728591
MLS001333983
MolPort-001-794-653
NCGC00025018-05
NCGC00025018-06
NCGC00025018-07
NSC19509
Prestwick0_000584
Prestwick1_000584
Prestwick2_000584
Prestwick3_000584
Quebrachin
Quebrachine
SMP1_000320
SMR000058527
SMR000470778
SPBio_002647
STOCK1N-51304
Thybine
UNII-2Y49VWD90Q
Yocon
Yohimar
Yohimban-16-.alpha.-carboxylic acid, 17-.alpha.-hydroxy-, methyl ester
Yohimban-16-alpha-carboxylic acid, 17-alpha-hydroxy-, methyl ester
Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16alpha,17alpha)- (9CI)
Yohimban-16alpha-carboxylic acid, 17alpha-hydroxy-, methyl ester (8CI)
Yohimbic acid methyl ester
Yohimbin
Yohimbine
Yohimbine (DCF)
Yohimbol-16alpha-carboxylic acid, methyl ester (6CI)
Yohimex
Yoman
Yovital
methyl (16alpha,17alpha)-17-hydroxyyohimban-16-carboxylate
methyl 17alpha-hydroxyyohimban-16alpha-carboxylate
nchembio.188-comp13
nchembio705-2
trans-Quinolizidine yohimbine
12
Norepinephrineapproved20651-41-2439260
Synonyms:
(-)-(R)-Norepinephrine
(-)-Arterenol
(-)-Arterenol free base
(-)-NORADRENALINE
(-)-Noradrenaline
(-)-Norepinephrine
(-)-alpha-(Aminomethyl)protocatechuyl alcohol
(R)-(-)-Norepinephrine
(R)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol
(R)-4-(2-amino-1-Hydroxyethyl)-1,2-benzenediol
(R)-Noradrenaline
(R)-Norepinephrine
1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (R)- (9CI)
4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol
4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol
4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol
4899-05-2
51-40-1 (l-tartrate (1:1))
51-41-2
66197-73-7
A7257_SIGMA
AC1L96ZT
ALBB-006229
Adrenor
Aktamin
Arterenol
BRN 4231961
BSPBio_002079
C00547
CHEBI:18357
CHEMBL1437
CID439260
D-(-)-Noradrenaline
D00076
D53D5E3A-2360-4CA9-8031-6C2CD4062FD5
DB00368
DivK1c_000230
EINECS 200-096-6
HMS1920B08
HMS2089E18
HMS2091J08
HMS500L12
IDI1_000230
KBio1_000230
KBio2_001489
KBio2_004057
KBio2_006625
KBio3_001579
KBioGR_000635
KBioSS_001489
L-2-Amino-1-(3,4-dihydroxyphenyl)ethanol
L-3,4-Dihydroxyphenylethanolamine
L-3,4-dihydroxyphenylethanolamine
L-Arterenol
L-Noradrenaline
L-Norepinephrine
L-alpha-(Aminomethyl)-3,4-dihydroxybenzyl alcohol
L-alpha-(aminomethyl)-3,4-dihydroxybenzyl alcohol
L-arterenol
L-noradrenaline
LS-42676
 
LT03330026
LT4
Levarterenol
Levarterenolo
Levarterenolo [DCIT]
Levoarterenol
Levonor
Levonoradrenaline
Levonorepinephrine
Levophed
NCGC00159406-02
NCGC00159406-03
NCGC00159406-04
NCGC00159406-05
NCGC00159406-06
NCGC00159406-07
NCGC00159406-09
NINDS_000230
Nor adrenalin
Nor adrenalin (TN)
Nor-Epirenan
Noradrenalin
Noradrenalina
Noradrenalina [Italian]
Noradrenaline
Noradrenaline (JP15)
Noradrenalinum
Norartrinal
Noreinefrina
Noreinefrina [INN-Spanish]
Norepinefrina
Norepinephrine
Norepinephrine (INN)
Norepinephrine Noradrenalin
Norepinephrine [INN:JAN]
Norepinephrine l-Tartrate (1:1)
Norepinephrinum
Norepinephrinum [INN-Latin]
Norepirenamine
PDSP1_001111
PDSP2_001095
SGCUT00123
SPBio_001048
SPECTRUM1500436
STK503776
Spectrum2_001064
Spectrum3_000520
Spectrum4_000078
Spectrum5_001068
Spectrum_001009
Sympathin E
UNII-X4W3ENH1CV
bmse000404
l-1-(3,4-Dihydroxyphenyl)-2-aminoethanol
l-2-Amino-1-(3,4-dihydroxyphenyl)ethanol
nchembio.284-comp2
nchembio.64-comp2
nchembio705-1
noradrenaline
norepinefrina
norepinephrine
norepinephrinum
to_000024
13
Guanfacineapproved, investigational5229110-47-23519
Synonyms:
29110-47-2
29110-48-3 (mono-hydrochloride)
AC1L1G4B
BPBio1_000415
BRD-K32830106-003-03-0
BSPBio_000377
C07037
C9H9Cl2N3O
CAS-29110-48-3
CHEMBL862
CID3519
D08031
DB01018
EINECS 249-442-8
Estulic
Estulic (TN)
G1043_SIGMA
GUANFACINE
Guanfacina
Guanfacina [INN-Spanish]
Guanfacine
Guanfacine (INN)
Guanfacine Hydrochloride
Guanfacine Monohydrochloride
Guanfacine [INN:BAN]
Guanfacinum
 
Guanfacinum [INN-Latin]
Intuniv
L000286
L013430
LS-174236
Lon798
Lopac-G-1043
Lopac0_000519
MolPort-003-941-447
N (Aminoiminomethyl)-2,6-dichlorobenzeneacetamide
N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide
NCGC00015469-01
NCGC00015469-02
NCGC00015469-06
NCGC00024950-01
NCGC00024950-02
NCGC00024950-03
Prestwick0_000339
Prestwick1_000339
Prestwick2_000339
Prestwick3_000339
SPBio_002298
SPD 503
Tenex
Tocris-1030
UNII-30OMY4G3MK
ZINC03872738
14Detox adjuvant23
15YohimbeNutraceutical25

Interventional clinical trials:

(show all 20)
idNameStatusNCT IDPhase
1Efficacy of a Triptan in the Treatment of Hostility and Aggression Among Convicts With a Psychiatric Treatment OrderTerminatedNCT00282165Phase 4
2Effect of Omega-3 Supplementation on Child Behavior ProblemsCompletedNCT02016079Phase 2, Phase 3
3Personality-targeted Interventions for Adolescent Alcohol MisuseCompletedNCT00344474Phase 2, Phase 3
4The Impact of Psychopathic Traits on the Efficacy of a Substance Use InterventionRecruitingNCT01532934Phase 2
5Working Memory Training in Adults With Substance Abuse and Executive Function Deficits.RecruitingNCT02068261Phase 2
6Vasopressin Effects on Human Social CommunicationRecruitingNCT01327027Phase 2
7Justice-Involved Veterans and Moral Reconation TherapyNot yet recruitingNCT02524171Phase 2
8Conduct Disorder in Prison: Search for Prospective and Retrospective Recurring and Contextual ElementsCompletedNCT02493088
9Matching Cognitive Remediation to Cognitive Deficits in Substance-Abusing InmatesCompletedNCT01428349
10Impaired Decision-making in AdolescentsCompletedNCT01253993Phase 0
11Psychological Mechanisms of Behavioral DysregulationCompletedNCT00352456
12The Role of Norepinephrine in Emotional ProcessingCompletedNCT00109642
13Early Exposure to Lead and Adult Antisocial OutcomesCompletedNCT00285610
14To Evaluate the Safety and Metabolic Profile of Vyvanse for the Treatment of ADHD in Euthymic Adults With Bipolar I/II DisorderCompletedNCT01263548
15Study of Children at Risk for Disruptive Behavior DisordersCompletedNCT00001233
16Antisocial Behavior: Passing From Parent to Child to GrandchildRecruitingNCT00060788
17The Effect of Prefrontal Cortex Stimulation on Antisocial and Aggressive BehaviorRecruitingNCT02427672
18ADHD: Gaps Between Patients With Alcohol-dependence and Impact on RelapseRecruitingNCT02364817
19Mental Health Related to School Dropout in LuxembourgEnrolling by invitationNCT01354236
20The Effect of Repeated Prefrontal Cortex Stimulation on Antisocial and Aggressive BehaviorNot yet recruitingNCT02674516

Search NIH Clinical Center for Antisocial Personality Disorder


Cochrane evidence based reviews: Antisocial Personality Disorder

Genetic Tests for Antisocial Personality Disorder

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Anatomical Context for Antisocial Personality Disorder

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MalaCards organs/tissues related to Antisocial Personality Disorder:

33
Cortex, Prefrontal cortex, Brain, Eye, Testes

Animal Models for Antisocial Personality Disorder or affiliated genes

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MGI Mouse Phenotypes related to Antisocial Personality Disorder:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.1ALDH2, DRD2, PRL, SLC6A3, SLC6A4
2MP:00053767.2ALDH2, DRD2, MAOA, MAOB, PRL, SLC6A3
3MP:00053867.1ALDH2, DRD2, MAOA, MAOB, PRL, SLC6A3
4MP:00036316.9ALDH2, DRD2, MAOA, MAOB, PRL, SLC6A3

Publications for Antisocial Personality Disorder

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Articles related to Antisocial Personality Disorder:

(show top 50)    (show all 335)
idTitleAuthorsYear
1
The Natural History of Antisocial Personality Disorder. (26175389)
2015
2
Changes in low-frequency fluctuations in patients with antisocial personality disorder revealed by resting-state functional MRI. (24598769)
2014
3
Physiological correlates of psychopathy, antisocial personality disorder, habitual aggression, and violence. (25129139)
2014
4
DSM-5 Antisocial Personality Disorder: Predictive Validity in a Prison Sample. (25180763)
2014
5
Examining the associations between DSM-5 section III antisocial personality disorder traits and psychopathy in community and university samples. (24689766)
2014
6
Comorbidity of social anxiety disorder and antisocial personality disorder in the National Epidemiological Survey on Alcohol and Related Conditions (NESARC). (24384071)
2013
7
Antisocial Personality Disorder Subscale (Chinese Version) of the Structured Clinical Interview for the DSM-IV Axis II disorders: validation study in Cantonese-speaking Hong Kong Chinese. (23807628)
2013
8
The role of fearless dominance in differentiating psychopathy from antisocial personality disorder: comment on Marcus, Fulton, and Edens. (23339316)
2013
9
Reduced cortical call to arms differentiates psychopathy from antisocial personality disorder. (22850322)
2013
10
The social-cognitive basis of borderline and antisocial personality disorder: introduction. (23342953)
2013
11
The relationship between adult reactive and proactive aggression, hostile interpretation bias, and antisocial personality disorder. (23342957)
2013
12
The association of 5-HTR2A-1438A/G, COMTVal158Met, MAOA-LPR, DATVNTR and 5-HTTVNTR gene polymorphisms and antisocial personality disorder in male heroin-dependent Chinese subjects. (22138326)
2012
13
White matter microstructural abnormalities in the frontal lobe of adults with antisocial personality disorder. (21777912)
2012
14
Borderline but not antisocial personality disorder symptoms are related to self-reported partner aggression in late middle-age. (22732005)
2012
15
Electroencephalographic abnormalities in antisocial personality disorder. (22152445)
2012
16
Childhood Maltreatment and Prospectively Observed Quality of Early Care as Predictors of Antisocial Personality Disorder Features. (22754051)
2012
17
Crack users show high rates of antisocial personality disorder, engagement in illegal activities and other psychosocial problems. (22691017)
2012
18
Diagnosis of antisocial personality disorder and criminal responsibility. (21903271)
2011
19
Gene environment interactions with a novel variable Monoamine Oxidase A transcriptional enhancer are associated with antisocial personality disorder. (21554924)
2011
20
Antisocial personality disorder is on a continuum with psychopathy. (20579518)
2010
21
Diagnosis and subtypes of adolescent antisocial personality disorder. (20420477)
2010
22
Incremental effect for antisocial personality disorder genetic risk combining 5-HTTLPR and 5-HTTVNTR polymorphisms. (20363030)
2010
23
Borderline Personality Disorder, Bulimia Nervosa, Antisocial Personality Disorder, ADHD, Substance Use: Common Threads, Common Treatment Needs, and the Nature of Impulsivity. (21253443)
2010
24
MAOA-uVNTR polymorphism may modify the protective effect of ALDH2 gene against alcohol dependence in antisocial personality disorder. (19302089)
2009
25
Frontal brain dysfunction in alcoholism with and without antisocial personality disorder. (19557141)
2009
26
A treatment guideline for people with antisocial personality disorder: overcoming attitudinal barriers and evidential limitations. (19343700)
2009
27
Qualitative and quantitative EEG abnormalities in violent offenders with antisocial personality disorder. (19134998)
2009
28
The relationship between distress tolerance and antisocial personality disorder among male inner-city treatment seeking substance users. (18834298)
2008
29
Correspondence between self-report and interview-based assessments of antisocial personality disorder. (18315398)
2008
30
Increased anxiety and other similarities in temperament of alcoholics with and without antisocial personality disorder across three diverse populations. (17452294)
2007
31
Conduct disorder and antisocial personality disorder in persons with severe psychiatric and substance use disorders. (16574783)
2006
32
Psychopathy/antisocial personality disorder conundrum. (16756576)
2006
33
Etiology of antisocial personality disorder: benefits for society from an evolutionary standpoint. (16006050)
2005
34
Borderline personality disorder, antisocial personality disorder and risk-taking among heroin users: findings from the Australian Treatment Outcome Study (ATOS). (15072810)
2004
35
Mate similarity for substance dependence and antisocial personality disorder symptoms among parents of patients and controls. (15276222)
2004
36
Neither antisocial personality disorder nor antisocial alcoholism is associated with the MAO-A gene in Han Chinese males. (12824808)
2003
37
Increased impulsivity in cocaine dependent subjects independent of antisocial personality disorder and aggression. (12167556)
2002
38
Diagnosing antisocial personality disorder among substance abusers: the scid versus the MCMI-II. (11727884)
2001
39
Risk factors in childhood that lead to the development of conduct disorder and antisocial personality disorder. (11196010)
2001
40
Conduct disorder, antisocial personality disorder and substance use disorders in schizophrenia and major affective disorders. (10091967)
1999
41
Therapeutic community treatment for substance abusers with antisocial personality disorder. (10435260)
1999
42
Gender differences in the relationship of antisocial personality disorder criteria to Psychopathy Checklist-Revised scores. (9573521)
1998
43
Gender and drug differences in antisocial personality disorder. (9169384)
1997
44
An ethical framework for understanding patients with antisocial personality disorder who develop dementia: diagnosing and managing disorders of autonomy. (11656997)
1997
45
Death rates in 71 men with antisocial personality disorder. A comparison with general population mortality. (8742541)
1996
46
A 16- to 45-year follow-up of 71 men with antisocial personality disorder. (7758299)
1995
47
Antisocial personality disorder as a prognostic factor for pharmacotherapy of cocaine dependence. (8082553)
1994
48
Drinking outcomes of alcohol abusers diagnosed as antisocial personality disorder. (7978086)
1994
49
Personality and disinhibitory psychopathology: alcoholism and antisocial personality disorder. (8040486)
1994
50
A case of pseudologia fantastica with antisocial personality disorder. (1742719)
1991

Variations for Antisocial Personality Disorder

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Expression for genes affiliated with Antisocial Personality Disorder

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Search GEO for disease gene expression data for Antisocial Personality Disorder.

Pathways for genes affiliated with Antisocial Personality Disorder

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Pathways related to Antisocial Personality Disorder according to GeneCards Suite gene sharing:

(show all 15)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8MAOA, SLC6A4
2
Show member pathways
9.6ALDH2, MAOA
39.6MAOA, MAOB
4
Show member pathways
9.6MAOA, MAOB
59.5MAOB, SLC6A3
6
Show member pathways
9.4MAOA, SLC6A3, SLC6A4
7
Show member pathways
9.2ALDH2, MAOA, SLC6A3
89.1ALDH2, MAOA, MAOB
9
Show member pathways
9.1ALDH2, MAOA, MAOB
10
Show member pathways
9.1ALDH2, MAOA, MAOB
11
Show member pathways
9.1ALDH2, MAOA, MAOB
12
Show member pathways
9.1ALDH2, MAOA, MAOB
13
Show member pathways
8.9DRD2, MAOA, MAOB, SLC6A3
14
Show member pathways
8.5DRD2, MAOA, MAOB, SLC6A3, SLC6A4
15
Show member pathways
8.1DRD2, MAOA, MAOB, PRL, SLC6A3

GO Terms for genes affiliated with Antisocial Personality Disorder

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Biological processes related to Antisocial Personality Disorder according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1adenohypophysis developmentGO:002198410.3DRD2, SLC6A3
2monoamine transportGO:001584410.3SLC6A3, SLC6A4
3positive regulation of multicellular organism growthGO:004001810.2DRD2, SLC6A3
4neurotransmitter transportGO:000683610.1SLC6A3, SLC6A4
5prepulse inhibitionGO:00601349.9DRD2, SLC6A3
6response to cocaineGO:00422209.7DRD2, SLC6A3
7neurotransmitter biosynthetic processGO:00421369.6ALDH2, MAOA, SLC6A3
8dopamine catabolic processGO:00424209.6MAOA, MAOB, SLC6A3
9lactationGO:00075959.5PRL, SLC6A3
10xenobiotic metabolic processGO:00068059.4ALDH2, MAOA, MAOB
11response to toxic substanceGO:00096369.3DRD2, MAOB, SLC6A4
12response to drugGO:00424939.1DRD2, MAOB, SLC6A4
13synaptic transmissionGO:00072688.9ALDH2, MAOA, SLC6A3, SLC6A4

Molecular functions related to Antisocial Personality Disorder according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1neurotransmitter:sodium symporter activityGO:000532810.2SLC6A3, SLC6A4
2monoamine transmembrane transporter activityGO:000850410.1SLC6A3, SLC6A4
3primary amine oxidase activityGO:000813110.0MAOA, MAOB
4dopamine bindingGO:00352409.7DRD2, SLC6A3
5oxidoreductase activityGO:00164919.1ALDH2, MAOA, MAOB

Sources for Antisocial Personality Disorder

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet