MCID: ANR004
MIFTS: 57

Anuria malady

Nephrological diseases category
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Summaries for Anuria

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65Wikipedia, 33MalaCards
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Wikipedia:65 Anuria means nonpassage of urine, in practice is defined as passage of less than 100 milliliters of... more...

MalaCards: Anuria, also known as suppression of urinary secretion, is related to nephritis and peritonitis. An important gene associated with Anuria is MB (myoglobin), and among its related pathways are Aldosterone-regulated sodium reabsorption and Peptide hormone metabolism. The drugs mannitol and mannitol hexanitrate and the compounds glycyrrhetinic acid and doca have been mentioned in the context of this disorder. Affiliated tissues include kidney, liver and heart, and related mouse phenotypes are behavior/neurological and muscle.

Aliases & Classifications for Anuria

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8Disease Ontology, 10DISEASES, 45Novoseek, 62UMLS, 58SNOMED-CT, 35MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Nephrological diseases


Aliases & Descriptions:

anuria 8 10 45 62
suppression of urinary secretion 8


External Ids:

Disease Ontology8 DOID:2983
MeSH35 D001002

Related Diseases for Anuria

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17GeneCards, 18GeneDecks
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Diseases related to Anuria via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 200)
idRelated DiseaseScoreTop Affiliating Genes
1nephritis30.4ACE, ALB
2peritonitis30.4ALB, MB
3malignant hypertension30.3ACE, REN
4oligohydramnios30.2ACE
5hypertension30.1ACE, ALB, AGTR1, REN, HSD11B2, AGT
6ovarian hyperstimulation syndrome29.8ALB, REN
7cushing's syndrome29.8HSD11B2, REN
8renal tubular dysgenesis29.8AGTR1, AGT, REN
9nephrotic syndrome29.7ALB, ACE, AGT
10proteinuria29.7AGTR1, AGT, HSD11B2, REN, ACE, ALB
11myocardial infarction29.6NR3C2, ACE, MB, REN, AGT, AGTR1
12ureteral obstruction10.3
13hemolytic-uremic syndrome10.2
14uremia10.2
15aneurysm10.2
16burns10.2
17diarrhea10.2
18leukemia10.2
19nephrosis10.2
20fibromuscular dysplasia10.1REN
21vascular disease10.1MB
22hypoaldosteronism10.1REN
23congestive heart failure10.1REN
24purpura10.1
25mitral valve prolapse10.1AGTR1
26low renin hypertension10.1HSD11B2, REN
27gitelman syndrome10.1AGT, REN
28hypertension, diastolic10.1ACE, REN
29intestinal obstruction10.1ALB
30renal hypertension10.1ACE, REN
31apparent mineralocorticoid excess syndrome10.1HSD11B2, NR3C2
32pure autonomic failure10.1ACE, REN
33pseudohypoaldosteronism type ii10.0REN, NR3C2
34glucocorticoid-remediable aldosteronism10.0REN, NR3C2
35conn's syndrome10.0NR3C2, REN
36vesicoureteral reflux10.0AGT, AGTR1
37adrenocortical carcinoma10.0HSD11B2, AGTR1
38pseudohypoaldosteronism10.0NR3C2, REN
39erythrocytosis10.0ACE, AGTR1
40angioedema10.0ACE, AGT
41polycystic kidney disease, autosomal dominant10.0ACE, REN
42idiopathic edema10.0NR3C2, ACE
43hepatorenal syndrome10.0REN, ALB
44adrenal adenoma10.0REN, AGTR1
45cerebrovascular disease10.0AGTR1, ACE
46sudden cardiac death multi-gene panels10.0NR3C2, ACE
47renal artery disease10.0ACE, ALB
48hypertensive nephropathy10.0ACE, ALB
49autonomic neuropathy10.0ALB, REN
50urethritis10.0

Graphical network of the top 20 diseases related to Anuria:



Diseases related to anuria

Symptoms for Anuria

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Drugs & Therapeutics for Anuria

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Anuria

Search NIH Clinical Center for Anuria

Inferred drug relations via UMLS62/NDF-RT41:

Genetic Tests for Anuria

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Anatomical Context for Anuria

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33MalaCards
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MalaCards organs/tissues related to Anuria:

33
Kidney, Liver, Heart, Uterus, Bone marrow, Bone, Skeletal muscle, Breast, Placenta, Cervix, Cortex

Animal Models for Anuria or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Anuria:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.0AGT, HSD11B2, REN, ACE, NR3C2
2MP:00053697.9REN, ALB, HSD11B2, MB, AGT, NR3C2
3MP:00053857.3AGT, NR3C2, ACE, REN, HSD11B2, MB
4MP:00053787.3NR3C2, AGT, MB, ACE, AGTR1, REN
5MP:00053677.1REN, HSD11B2, AGT, AGTR1, NR3C2, ALB
6MP:00053766.7AGTR1, AGT, MB, NR3C2, ALB, ACE
7MP:00107686.5HSD11B2, ACE, AGTR1, ALB, NR3C2, MB

Publications for Anuria

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52PubMed
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Articles related to Anuria:

(show top 50)    (show all 490)
idTitleAuthorsYear
1
Renal recoverability in infants with obstructive calcular anuria: is it better than in older children? (23769201)
2013
2
Reflex anuria: an old concept with new evidence. (23979816)
2013
3
Neonate with abdominal lump and anuria. (20823988)
2010
4
Reflex anuria affecting both kidneys following hysterectomy. (19112230)
2009
5
Answer to case of the month #157 anuria in the supine position. (19931134)
2009
6
An unusual case of bilateral primitive obstructed megaureters due to ureteral valves presenting with anuria at the age of 1 month. (18022421)
2007
7
Bilateral pelvi-ureteric junction obstruction in a neonate presenting with sudden anuria. (18947670)
2006
8
Obstructive anuria due to fungal bezoars in a renal graft recipient. (14612076)
2003
9
Anuria due to bilateral ureteral obstruction by Aspergillus flavus in an adult male. (11927329)
2002
10
Bilateral percutaneous nephrolithotomy for multiple cystine stones in an infant presenting with anuria. (10754658)
1999
11
Anuria caused by bilateral iliac artery aneurysms. (9666792)
1998
12
Postrenal anuria in pelvic or acetabular injury: a report of three cases. (8913231)
1996
13
Reflex anuria. (7592301)
1995
14
Anuria secondary to percutaneous needle biopsy of a transplant kidney: a case report. (3294445)
1988
15
Anuria complicating urethrocystopexy. (3893026)
1985
16
Persistent clot anuria complicating renal transplant biopsy. (3892847)
1985
17
Transient fetal anuria of unknown etiology: a case report. (6720780)
1984
18
Successful surgical treatment of anuria caused by renal artery occlusion. (7059245)
1982
19
Glycolytic substrate utilization and energy consumption in the cerebral hemispheres of the mouse during experimental anuria. (615719)
1977
20
Post-obstructive anuria: a documented entity. (765505)
1976
21
Recovery after prolonged anuria following septic abortion. (1246389)
1976
22
Giant vesical calculas and anuria. (1273538)
1976
23
Distribution volumes in the dog kidney during anuria produced by uranium nitrate. (4868328)
1968
24
An acute abdominal catastrophe and anuria in a patient with rheumatic heart disease on anticoagulant therapy. (5666652)
1968
25
Acute parenchymal dysfunction with acute anuria induced by retrograde pyelography. (6017689)
1967
26
Acute renal failure in association with fatty liver of pregnancy. Recovery after fourteen days of complete anuria. (6024241)
1967
27
Anuria during pregnancy. Report of one case. (5969896)
1966
28
CLINICO-PATHOLOGICAL CONFERENCE. ACUTE ABDOMINAL PAIN, BLOODY DIARRHEA AND ANURIA. (14076465)
1964
29
Arsine induced anuria. (13936466)
1963
30
The problem of anuria. Diagnosis and treatment of acute renal failure. (14480846)
1961
31
Acute anuria associated with hyperkalemia. The role of gastric lavage. (13681967)
1961
32
Anuria due to carbon tetrachloride intoxication. (13545713)
1958
33
Djenkol bean poisoning (djenkolism); a cause of hematuria and anuria. (13339789)
1956
34
Electrolyte balance in a patient with anuria due to shock. (13374596)
1956
35
Dietary treatment in acute anuria. (13362132)
1956
36
Oliguria and anuria in obstetrics. (14363348)
1955
37
Anuria following phenylbutazone therapy. (14383969)
1955
38
Abortion anuria. (13125733)
1954
39
Some aspects of anuria in obstetrics and gynaecology. (13099584)
1953
40
Discussion on the treatment of anuria. (13014098)
1952
41
A study of anuria occurring during apnea under diffusion respiration. (14903119)
1952
42
LIMITATIONS of the artificial kidney in anuria. (13024456)
1952
43
Hyperpotassemia and hypopotassemia in case of anuria followed by severe diuresis; electrocardiographic changes. (14873614)
1951
44
Anuria and oliguria; treatment by conservative means, case report, with determination of blood volume and Na24 space. (15426982)
1950
45
Anuria and oliguria; a review of symptoms, pathologic physiology and mortality rates. (15414441)
1950
46
A case of anuria during combined sulfonamide therapy. (18111148)
1949
47
Anuria. (18127707)
1949
48
Oliguria and anuria in toxemias of pregnancy. (18110648)
1949
49
Anuria following ischaemia of the renal cortex. (18149306)
1949
50
Treatment of Anuria. (20787466)
1948

Variations for Anuria

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Expression for genes affiliated with Anuria

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Anuria

Search GEO for disease gene expression data for Anuria.

Pathways for genes affiliated with Anuria

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50PathCards, 30KEGG, 55Reactome, 38NCBI BioSystems Database, 53QIAGEN, 51PharmGKB
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Compounds for genes affiliated with Anuria

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45Novoseek, 24HMDB, 29IUPHAR, 11DrugBank, 51PharmGKB, 3BitterDB, 61Tocris Bioscience
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Compounds related to Anuria according to GeneCards/GeneDecks:

(show top 50)    (show all 153)
idCompoundScoreTop Affiliating Genes
1glycyrrhetinic acid45 2410.3HSD11B2, REN, NR3C2
2doca459.2NR3C2, REN, HSD11B2
3glycyrrhizin45 2910.2REN, HSD11B2, NR3C2
4inulin459.2AGT, ALB, REN
5remikiren45 1110.2ACE, AGT, REN
6lacidipine459.1REN, AGTR1, ACE
711beta-hydroxysteroid459.1HSD11B2, REN, NR3C2, AGTR1
8cilazapril45 1110.0REN, ACE, AGTR1
9trandolapril45 1110.0REN, AGTR1, ACE
10pd12331945 2910.0AGTR1, AGT, ACE
11indapamide45 119.9ACE, ALB, REN
12aliskiren45 119.8REN, AGT, ACE, AGTR1
13saralasin458.8REN, ACE, AGTR1, AGT
14eprosartan45 29 1110.8AGTR1, AGT, ACE, REN
15olmesartan45 29 1110.8AGT, AGTR1, ACE, REN
16benazepril45 51 1110.8AGTR1, ACE, AGT, REN
17chymostatin458.8REN, ACE, AGT, AGTR1
18atenolol45 51 29 24 1112.8AGT, REN, ACE, AGTR1
19haloperidol45 51 29 3 1112.7REN, AGT, NR3C2, AGTR1, MB
20quinapril45 51 1110.7AGTR1, REN, ACE
21diltiazem45 29 51 1111.7AGTR1, AGT, REN, ACE
22eplerenone45 61 29 1111.7AGTR1, ACE, REN, NR3C2
23thiazide458.7ACE, NR3C2, AGTR1, REN
24acth458.6NR3C2, AGTR1, REN, HSD11B2, AGT
25felodipine45 29 1110.6ACE, REN, AGTR1, NR3C2
26fosinopril45 119.6AGTR1, REN, ACE, ALB
27enalaprilat458.6REN, ACE, AGT
28ramipril45 119.6AGTR1, ALB, REN, ACE
29ang ii458.3NR3C2, AGT, ACE, REN, AGTR1
30furosemide45 61 29 51 24 1113.3AGTR1, ALB, ACE, REN, HSD11B2
31lisinopril45 51 24 1111.2ACE, REN, ALB, AGT, AGTR1
32valsartan45 61 29 1111.2AGTR1, REN, AGT, ALB, ACE
33telmisartan45 29 1110.2REN, ALB, AGT, ACE, AGTR1
34perindopril45 51 1110.2AGTR1, AGT, ACE, ALB, REN
35irbesartan45 29 51 1111.2AGT, ALB, ACE, REN, AGTR1
36candesartan45 51 29 1111.2AGTR1, REN, AGT, ALB, ACE
37amlodipine45 51 24 1111.2ALB, AGT, AGTR1, REN, ACE
38arginine458.2HSD11B2, AGT, REN, MB, NR3C2, AGTR1
39estradiol45 24 1110.1ALB, AGT, NR3C2, REN, HSD11B2, AGTR1
40spironolactone45 61 29 51 1111.8ACE, REN, ALB, NR3C2, AGTR1, HSD11B2
41enalapril45 51 119.7NR3C2, AGTR1, AGT, ALB, REN, ACE
42captopril45 61 51 29 1111.7REN, ACE, ALB, NR3C2, AGTR1, AGT
43losartan45 51 29 1110.7AGTR1, ACE, AGT, NR3C2, ALB, REN
44norepinephrine45 24 119.6AGTR1, AGT, MB, ACE, REN, HSD11B2
45hydrochlorothiazide45 29 51 24 1111.4REN, HSD11B2, ACE, ALB, NR3C2, AGT
46potassium45 24 119.3HSD11B2, REN, NR3C2, ALB, AGTR1, ACE
47sodium45 248.3ALB, REN, ACE, NR3C2, AGT, AGTR1
48cholesterol45 29 24 1110.3AGT, ALB, NR3C2, ACE, REN, HSD11B2
49glucose457.2HSD11B2, ACE, AGTR1, AGT, NR3C2, ALB
50creatinine457.0HSD11B2, ACE, REN, ALB, NR3C2, MB

GO Terms for genes affiliated with Anuria

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16Gene Ontology
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Cellular components related to Anuria according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.2AGT, ALB, ACE, REN

Biological processes related to Anuria according to GeneCards/GeneDecks:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of NAD(P)H oxidase activityGO:0338649.9AGT, AGTR1
2regulation of blood vessel size by renin-angiotensinGO:0020349.9AGT, AGTR1
3regulation of renal sodium excretionGO:0358139.9AGTR1, AGT
4positive regulation of cholesterol esterificationGO:0108739.9AGTR1, AGT
5low-density lipoprotein particle remodelingGO:0343749.8AGT, AGTR1
6positive regulation of cellular protein metabolic processGO:0322709.8AGTR1, AGT
7positive regulation of macrophage derived foam cell differentiationGO:0107449.8AGTR1, AGT
8positive regulation of reactive oxygen species metabolic processGO:20003799.7AGT, AGTR1
9phospholipase C-activating G-protein coupled receptor signaling pathwayGO:0072009.6AGTR1, AGT
10regulation of cell growthGO:0015589.6AGTR1, AGT
11renin-angiotensin regulation of aldosterone productionGO:0020189.6AGTR1, AGT, REN
12regulation of renal output by angiotensinGO:0020199.5AGT, ACE
13positive regulation of inflammatory responseGO:0507299.5AGT, AGTR1
14regulation of systemic arterial blood pressure by renin-angiotensinGO:0030819.5ACE, AGTR1
15regulation of vasodilationGO:0423129.4AGTR1, ACE
16blood vessel remodelingGO:0019749.3AGT, ACE
17angiotensin maturationGO:0020039.2REN, ACE, AGT
18regulation of vasoconstrictionGO:0192299.1ACE, AGT, AGTR1
19regulation of blood pressureGO:0082179.0ACE, REN
20kidney developmentGO:0018228.7AGTR1, AGT, ACE, REN

Molecular functions related to Anuria according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1steroid bindingGO:0054969.5NR3C2, HSD11B2
2oxygen bindingGO:0198259.2MB, ALB
3bradykinin receptor bindingGO:0317119.2AGTR1, ACE
4drug bindingGO:0081449.0ALB, ACE

Products for genes affiliated with Anuria

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Sources for Anuria

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet