Aliases & Classifications for Anuria

MalaCards integrated aliases for Anuria:

Name: Anuria 12 52 42 14 69
Suppression of Urinary Secretion 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2983
MeSH 42 D001002
NCIt 47 C114699
UMLS 69 C0003460

Summaries for Anuria

MalaCards based summary : Anuria, also known as suppression of urinary secretion, is related to renal tubular dysgenesis and pyelonephritis, and has symptoms including oliguria and anuria, polyuria and suppressed urine secretion. An important gene associated with Anuria is ACE (Angiotensin I Converting Enzyme), and among its related pathways/superpathways are Peptide hormone metabolism and Renin secretion. The drugs Epinephrine and Mannitol have been mentioned in the context of this disorder. Affiliated tissues include kidney, liver and heart, and related phenotypes are behavior/neurological and cardiovascular system

Wikipedia : 72 Anuria, sometimes called anuresis, is nonpassage of urine, in practice is defined as passage of less... more...

Related Diseases for Anuria

Diseases related to Anuria via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 174)
id Related Disease Score Top Affiliating Genes
1 renal tubular dysgenesis 31.7 ACE AGT AGTR1 REN
2 pyelonephritis 29.8 ACE PIK3C2A REN
3 glomerulonephritis 29.4 MB PIK3C2A
4 myocardial infarction 26.2 ACE AGT AGTR1 ALB MB NR3C2
5 hypothyroidism due to iodide transport defect 10.7 ACE REN
6 primary hyperoxaluria 10.7 ACE REN
7 pelizaeus-merzbacher-like disease 10.7 ACE AGT
8 atrial septal defect 7, with or without av conduction defects 10.7 ACE REN
9 mody, type ii 10.7 ACE REN
10 hypodontia of incisors and premolars 10.7 ACE REN
11 listeriosis 10.7 ACE REN
12 voyeurism 10.6 ACE REN
13 cystic fibrosis and congenital absence of the vas deferens 10.6 AGTR1 REN
14 wernicke-korsakoff syndrome 10.6 ALB REN
15 iga glomerulonephritis 10.6 ALB REN
16 retinitis pigmentosa 70 10.6 ACE ALB
17 familial isolated pituitary adenoma 10.6 AGT AGTR1
18 pyogenic arthritis, pyoderma gangrenosum and acne 10.5 ACE REN
19 mental retardation cataracts calcified pinnae myopathy 10.5 AGT AGTR1
20 synovial chondromatosis 10.5 ACE ALB
21 pulmonary valve insufficiency 10.5 ACE REN
22 colon leiomyoma 10.5 ACE PIK3C2A
23 clear cell acanthoma 10.5 HSD11B2 REN
24 primary polycythemia 10.5 ACE PIK3C2A
25 marden-walker syndrome 10.5 NR3C2 REN
26 hypertension, early-onset, autosomal dominant, with exacerbation in pregnancy 10.4 NR3C2 REN
27 capillary hemangioma 10.4 ALB REN
28 long qt syndrome 13 10.4 NR3C2 REN
29 bernard-soulier syndrome, type a2 10.4 ACE AGTR1
30 clitoris cancer 10.4 ACE AGTR1 REN
31 idiopathic juxtafoveal retinal telangiectasia 10.4 ACE NR3C2
32 placental abruption 10.4 ACE NR3C2
33 craniosynostosis 7 10.4 ACE AGT REN
34 lymphadenitis 10.4 ACE AGTR1 REN
35 cataract, autosomal dominant congenital 4 10.3 ACE AGT AGTR1
36 potato nose 10.3 ACE AGT AGTR1
37 aortopulmonary window 10.3 ACE AGT AGTR1
38 trichinosis 10.3 ACE AGT AGTR1
39 non-congenital cyst of kidney 10.3 ACE ALB REN
40 localized chondrosarcoma 10.3 ALB PIK3C2A
41 joint disorders 10.3 ACE AGT AGTR1
42 myopia 10.3 ACE ALB REN
43 thoracic spinal canal and spinal cord meningioma 10.3 ACE AGT AGTR1
44 episodic ataxia 10.3 ACE AGT AGTR1
45 ostertagiasis 10.3 ACE PIK3C2A
46 malignant type ab thymoma 10.3 ACE AGTR1 REN
47 hypertrichosis 10.3 ACE ALB REN
48 survival motor neuron spinal muscular atrophy 10.3 ACE ALB REN
49 pyrimidine metabolic disorder 10.3 ALB PIK3C2A
50 common cold 10.3 ALB PIK3C2A

Graphical network of the top 20 diseases related to Anuria:



Diseases related to Anuria

Symptoms & Phenotypes for Anuria

UMLS symptoms related to Anuria:


oliguria and anuria, polyuria, suppressed urine secretion, kidney problem

MGI Mouse Phenotypes related to Anuria:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.97 ACE AGT AGTR1 HSD11B2 LRSAM1 NR3C2
2 cardiovascular system MP:0005385 9.92 PIK3C2A REN ACE AGT AGTR1 HSD11B2
3 homeostasis/metabolism MP:0005376 9.91 ACE AGT AGTR1 ALB HSD11B2 MB
4 mortality/aging MP:0010768 9.81 ACE AGT AGTR1 ALB HSD11B2 MB
5 muscle MP:0005369 9.43 ALB HSD11B2 MB NR3C2 REN AGT
6 renal/urinary system MP:0005367 9.23 ACE AGT AGTR1 ALB HSD11B2 NR3C2

Drugs & Therapeutics for Anuria

Drugs for Anuria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 26)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
2
Mannitol Approved, Investigational Phase 4 69-65-8 453 6251
3
Nitric Oxide Approved Phase 4 10102-43-9 145068
4
Prilocaine Approved Phase 4 721-50-6 4906
5 Racepinephrine Approved Phase 4
6 diuretics Phase 4
7 Epinephryl borate Phase 4
8 Natriuretic Agents Phase 4
9 Pharmaceutical Solutions Phase 4,Phase 1
10
Irbesartan Approved, Investigational Phase 3 138402-11-6 3749
11
Angiotensin II Investigational Phase 3 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
12 Angiotensin II Type 1 Receptor Blockers Phase 3
13 Angiotensin Receptor Antagonists Phase 3
14 Angiotensinogen Phase 3
15 Antihypertensive Agents Phase 3
16 Shiga Toxins Phase 1
17
Benazepril Approved, Investigational 86541-75-5 5362124
18
Benzocaine Approved 1994-09-7, 94-09-7 2337
19
Valsartan Approved, Investigational 137862-53-4 60846
20 tannic acid Approved, Nutraceutical
21 Anesthetics
22 Adrenergic beta-Antagonists
23 Angiotensin-Converting Enzyme Inhibitors
24 HIV Protease Inhibitors
25
protease inhibitors
26 Dialysis Solutions

Interventional clinical trials:

(show all 16)

id Name Status NCT ID Phase Drugs
1 Early Continuous Renal Replacement Therapies (CRRT) in Patients With Severe Sepsis or Septic Shock With Acute Kidney Injury Unknown status NCT00837057 Phase 4
2 Control Of Fluid Balance Guided by Body Composition Monitoring in Patients on PeritoneAl dialySiS Unknown status NCT01887262 Phase 4
3 Randomized Controlled Trial Comparing Residual Kidney Function in Patients Undergoing Three or Four Exchanges CAPD Completed NCT01637792 Phase 4
4 Evaluation of Ureteral Patency in the Post-indigo Carmine Era Completed NCT02677623 Phase 4 Pyridium;Sodium Fluorescein;Mannitol
5 Saving Residual Renal Function Among Haemodialysis Patients Receiving Irbesartan Completed NCT00791830 Phase 3 Irbesartan;Placebo matching irbesartan 150 mg
6 Study to Evaluate the Safety and Efficacy of the Renal Assist Device in Patients With Acute Renal Failure Terminated NCT00280072 Phase 2
7 Shiga Toxin Producing Escherichia Coli (STEC) Volume Expansion Not yet recruiting NCT03275792 Phase 1 D5-0.9%NS;Routine home oral rehydration
8 Delayed or Direct Ureteroscopy in the Treatment of Pediatric Calcular Anuria Unknown status NCT02139059
9 Ureteral Stents Versus Percutaneous Nephrostomy for Initial Urinary Drainage Completed NCT02055430
10 Hemodialysis Frequency and the Calcification Propensity of Serum Completed NCT01975025
11 Artificial Kidney Initiation in Kidney Injury Completed NCT01932190
12 Renal Tubular Acidosis is Highly Prevalent in Critically Ill Patients Completed NCT02392091
13 The Intermittent Pneumoperitoneum Scheme of Work Breaks in Complex Laparoscopic Surgery Completed NCT01009372
14 Renal Protective Effects of Renin Angiotensin System (RAS) Inhibitor in Peritoneal Dialysis Patients Completed NCT00721773 Benazepril;Valsartan;Benazepril+Valsartan;Control
15 Myoglobin Removal by High Cut-off CVVHD Completed NCT01467180
16 Intraoperative Anuric Episodes in Patients Undergoing Laparotomy Withdrawn NCT01703442

Search NIH Clinical Center for Anuria

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: anuria

Genetic Tests for Anuria

Anatomical Context for Anuria

MalaCards organs/tissues related to Anuria:

39
Kidney, Liver, Heart, Uterus, Breast, Placenta, Cervix

Publications for Anuria

Articles related to Anuria:

(show top 50) (show all 526)
id Title Authors Year
1
Re: Anuria Since Birth: Does it Impact Outcome of Kidney Transplant in Infants? ( 28093185 )
2017
2
A rare cause of anuria in a case of pre-B acute lymphoblastic leukaemia. ( 28566415 )
2017
3
Irreversible severe kidney injury and anuria in a 3-month-old girl with atypical haemolytic uraemic syndrome under administration of eculizumab. ( 26818219 )
2016
4
Duration of anuria predicts recovery of renal function after acute kidney injury requiring continuous renal replacement therapy. ( 26867084 )
2016
5
Anuria Secondary to Bilateral Obstructing Ureteral Stones in the Absence of Renal Colic. ( 27579429 )
2016
6
Anuria after renal graft biopsy: Multidisciplinary intervention. ( 26857206 )
2016
7
Point-of-Care Ultrasound to Assess Anuria in Children. ( 27490729 )
2016
8
Quiz Page December 2016: Anuria on the Second Day Following Kidney Transplantation. ( 27884282 )
2016
9
Role of anuria in the relationship between indoxyl sulfate and anemia in peritoneal dialysis patients. ( 27932887 )
2016
10
Anuria since birth: does it impact outcome of kidney transplant in infants? ( 27495879 )
2016
11
Acute anuria after a family vacation to Corsica/France. ( 26852123 )
2016
12
Point-of-Care Ultrasound to Assess Anuria in Children. ( 27490730 )
2016
13
Anuria and acute kidney injury: an uncommon case of bilateral synchronous ureteric calculi. ( 27241565 )
2016
14
Etiology and outcomes of anuria in acute kidney injury: a single center study. ( 26484014 )
2015
15
A rare cause of anuria: Bilateral synchronous isolated mid-ureteric tubercular lesions. ( 26604451 )
2015
16
Recovery of renal function after prolonged anuria in acute suprarenal aortic occlusion. ( 26520421 )
2015
17
Resolution of refractory hypotension and anuria in a premature newborn with loss-of-function of ACE. ( 26480306 )
2015
18
Subcapsular Hematoma Causing Anuria After Renal Graft Trauma. ( 26496471 )
2015
19
Resolution of refractory hypotension and anuria in a premature newborn with loss-of-function of ACE. ( 25899979 )
2015
20
A successful pregnancy and parturition in a patient with anuria undergoing maintenance hemodialysis for 6 years: a case report of a 3-year-follow-up. ( 26370296 )
2015
21
Focal segmental glomerular sclerosis recurrence with massive proteinuria and anuria immediately after kidney transplantation. ( 26031597 )
2015
22
Reflex anuria: a rare complication of prophylactic ureteral catheterization. ( 25943463 )
2015
23
Unusual Causes of Abrupt Anuria Early Post-Renal Transplantation. ( 26246931 )
2015
24
Successful management of repetitive urinary obstruction and anuria caused by double j stent calculi formation after renal transplantation. ( 25110605 )
2014
25
Perioperative Anuria Resulting in the Diagnosis of Infrasphincteric Ectopic Ureter in an Adult Female. ( 26955562 )
2014
26
Quiz page June 2014: a 45-year-old woman with acute anuria. ( 24856622 )
2014
27
Recurrent clot anuria following laparoscopic pyeloplasty in a solitary functioning kidney: managing with double guide wire technique. ( 25540210 )
2014
28
Management of calculus anuria using ureteroscopic lithotripsy as a first line treatment: its efficacy and safety. ( 24807749 )
2014
29
Reflex anuria: a rare cause of acute kidney injury. ( 24765255 )
2014
30
Ureteric stents vs percutaneous nephrostomy for initial urinary drainage in children with obstructive anuria and acute renal failure due to ureteric calculi: a prospective, randomised study. ( 24698195 )
2014
31
Management of obstructive calcular anuria with acute renal failure in children less than 4 years in age: A protocol for initial urinary drainage in relation to planned definitive stone management. ( 24953544 )
2014
32
Anuria due to inadvertent prostatectomy during cryptorchidectomy. ( 24155461 )
2013
33
Reflex anuria: an old concept with new evidence. ( 23979816 )
2013
34
Anuria in a solitary kidney with Candida bezoars managed conservatively. ( 24213483 )
2013
35
Reflex anuria following acute cardiac event. ( 23688052 )
2013
36
Anuria and abdominal pain induced by ceftriaxone-associated ureterolithiasis in adults. ( 23180444 )
2013
37
Renal recoverability in infants with obstructive calcular anuria: is it better than in older children? ( 23769201 )
2013
38
Family recurrence and oligo-anuria predict uremic restless legs syndrome. ( 21824115 )
2012
39
Reflux anuria after prophylactic ureteral catheter removal: a case description and review of the literature. ( 22192094 )
2012
40
Autologous creatinine clearance in a case of necrotizing fasciitis and anuria. ( 22343604 )
2012
41
An unusual cause of anuria and hydronephrosis in a 12-year-old girl. ( 21463179 )
2011
42
Assessment of recoverability of kidney function in children with obstructive calcular anuria: multicenter study. ( 21527220 )
2011
43
Intraoperative anuria: An unusual cause. ( 22144941 )
2011
44
Investigating the mechanism for maintaining eucalcemia despite immobility and anuria in the hibernating American black bear (Ursus americanus). ( 21893223 )
2011
45
Anuria in a 9-month-old infant resulting from ureteral cystine stones. ( 22025963 )
2011
46
Reflex anuria. ( 21884352 )
2011
47
Atypical hemolytic-uremic syndrome (HUS) with recovery after a long-lasting anuria: a case report. ( 21607045 )
2011
48
Unusual cause of postrenal biopsy anuria in a renal transplant patient. ( 21326078 )
2011
49
Massive gastric dilatation and anuria resolved with naso-gastric tube decompression. ( 20041295 )
2010
50
Acute renal failure and anuria associated with vitamin D intoxication in two alpaca (Vicugna pacos) cria. ( 20102501 )
2010

Variations for Anuria

Expression for Anuria

Search GEO for disease gene expression data for Anuria.

Pathways for Anuria

Pathways related to Anuria according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.39 ACE AGT REN
2 10.74 ACE AGT AGTR1 REN
3 10.72 HSD11B2 NR3C2

GO Terms for Anuria

Biological processes related to Anuria according to GeneCards Suite gene sharing:

(show all 21)
id Name GO ID Score Top Affiliating Genes
1 regulation of blood pressure GO:0008217 9.67 ACE AGT REN
2 protein catabolic process GO:0030163 9.6 LRSAM1 REN
3 positive regulation of protein tyrosine kinase activity GO:0061098 9.59 ACE AGT
4 blood vessel remodeling GO:0001974 9.58 ACE AGT
5 positive regulation of reactive oxygen species metabolic process GO:2000379 9.58 AGT AGTR1
6 positive regulation of cellular protein metabolic process GO:0032270 9.57 AGT AGTR1
7 positive regulation of macrophage derived foam cell differentiation GO:0010744 9.56 AGT AGTR1
8 kidney development GO:0001822 9.56 ACE AGT AGTR1 REN
9 beta-amyloid metabolic process GO:0050435 9.55 ACE REN
10 regulation of blood vessel diameter GO:0097746 9.54 ACE AGTR1
11 low-density lipoprotein particle remodeling GO:0034374 9.52 AGT AGTR1
12 positive regulation of cholesterol esterification GO:0010873 9.51 AGT AGTR1
13 regulation of vasoconstriction GO:0019229 9.5 ACE AGT AGTR1
14 positive regulation of NAD(P)H oxidase activity GO:0033864 9.48 AGT AGTR1
15 regulation of renal sodium excretion GO:0035813 9.46 AGT AGTR1
16 regulation of blood vessel diameter by renin-angiotensin GO:0002034 9.43 AGT AGTR1
17 regulation of blood volume by renin-angiotensin GO:0002016 9.4 AGT REN
18 regulation of renal output by angiotensin GO:0002019 9.37 ACE AGT
19 angiotensin maturation GO:0002003 9.33 ACE AGT REN
20 regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9.13 ACE AGT AGTR1
21 renin-angiotensin regulation of aldosterone production GO:0002018 8.8 AGT AGTR1 REN

Molecular functions related to Anuria according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 oxygen binding GO:0019825 9.16 ALB MB
2 steroid binding GO:0005496 8.96 HSD11B2 NR3C2
3 bradykinin receptor binding GO:0031711 8.62 ACE AGTR1

Sources for Anuria

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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