MCID: ANR004
MIFTS: 55

Anuria malady

Nephrological diseases category

Summaries for Anuria

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63Wikipedia, 32MalaCards
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Wikipedia:63 Anuria means nonpassage of urine, in practice is defined as passage of less than 100 milliliters of... more...

MalaCards: Anuria, also known as suppression of urinary secretion, is related to uremia and hypertension. An important gene associated with Anuria is MB (myoglobin), and among its related pathways are Thromboxane signalling through TP receptor and Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics. The drugs mannitol and mannitol hexanitrate and the compounds norepinephrine and captopril have been mentioned in the context of this disorder. Affiliated tissues include kidney, liver and uterus, and related mouse phenotypes are muscle and cardiovascular system.

Aliases & Classifications for Anuria

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 34MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Nephrological diseases


Aliases & Descriptions:

anuria 8 10 44 60
suppression of urinary secretion 8


External Ids:

Disease Ontology8 DOID:2983
MeSH34 D001002

Related Diseases for Anuria

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17GeneCards, 18GeneDecks
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Diseases related to Anuria via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 211)
idRelated DiseaseScoreTop Affiliating Genes
1uremia30.3ALB
2hypertension30.3HSD11B2, FBXL20, NR3C2, AGTR1, AGT, REN
3peritonitis30.3ALB, MB
4leukemia30.1NR3C2
5malignant hypertension30.1REN, ACE
6diarrhea30.1ALB
7oligohydramnios29.9ACE
8renal hypertension29.9ACE, REN
9renal tubular dysgenesis29.9AGTR1, AGT, REN
10proteinuria29.9HSD11B2, FBXL20, NR3C2, AGTR1, AGT, REN
11cushing's syndrome29.7REN, HSD11B2
12glomerulonephritis29.7ALB, AGTR1
13ovarian hyperstimulation syndrome29.7ALB, REN
14acute kidney failure29.7MB, REN, ALB
15nephrotic syndrome29.7ALB, ACE, AGT
16breast cancer29.7HSD11B2, NR3C2, AGT, ALB
17myocardial infarction29.7MB, NR3C2, AGTR1, AGT, REN, ACE
18ureteral obstruction10.4
19hemolytic-uremic syndrome10.2
20burns10.1
21purpura10.1
22acromegaly10.0HSD11B2
23glaucoma10.0HSD11B2
24eosinophilia10.0MB
25myocarditis10.0MB
26cor pulmonale10.0AGTR1
27intermediate coronary syndrome10.0MB
28mitral valve prolapse10.0AGTR1
29dementia10.0AGTR1
30fibromuscular dysplasia10.0REN
31amyotrophic lateral sclerosis10.0MB
32proliferative diabetic retinopathy10.0AGT
33hypoaldosteronism10.0REN
34acute pancreatitis10.0MB
35urinary tract obstruction10.0ACE
36polycystic ovary syndrome10.0NR3C2
37rheumatoid arthritis10.0MB
38dilated cardiomyopathy10.0MB, ACE
39lupus nephritis10.0ALB
40vesicoureteral reflux10.0AGTR1, AGT
41cholestasis10.0ALB
42hepatitis c10.0ALB
43pulmonary fibrosis10.0AGT, AGTR1
44low renin hypertension10.0HSD11B2, REN
45galactosemia10.0ALB
46cerebrovascular disease10.0ACE, AGTR1
47apparent mineralocorticoid excess syndrome10.0HSD11B2, NR3C2
48hyperhomocysteinemia10.0ALB
49pancreatitis10.0ALB
50adenocarcinoma10.0AGTR1, HSD11B2

Graphical network of the top 20 diseases related to Anuria:



Diseases related to anuria

Clinical Features for Anuria

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Drugs & Therapeutics for Anuria

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Anuria

Drug clinical trials:

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Search NIH Clinical Center for Anuria

Search CenterWatch for Anuria

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Anuria

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Anatomical Context for Anuria

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32MalaCards
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MalaCards organs/tissues related to Anuria:

32
Kidney, Liver, Uterus, Heart, Placenta, Breast, Bone marrow, Skeletal muscle, Cortex, Bone, Cervix

Animal Models for Anuria or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Anuria:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.6REN, AGT, NR3C2, MB, HSD11B2
2MP:00053857.6HSD11B2, MB, NR3C2, AGTR1, AGT, REN
3MP:00053677.5ALB, HSD11B2, NR3C2, AGTR1, AGT, REN
4MP:00053787.1MB, FBXL20, NR3C2, AGTR1, AGT, REN
5MP:00053767.0HSD11B2, MB, NR3C2, AGTR1, AGT, REN
6MP:00107686.7HSD11B2, MB, FBXL20, NR3C2, AGTR1, AGT

Publications for Anuria

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Sources:
50PubMed
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Articles related to Anuria:

(show top 50)    (show all 495)
idTitleAuthorsYear
1
Anuria due to inadvertent prostatectomy during cryptorchidectomy. (24155461)
2013
2
Reflux anuria after prophylactic ureteral catheter removal: a case description and review of the literature. (22192094)
2012
3
An unusual cause of anuria and hydronephrosis in a 12-year-old girl. (21463179)
2011
4
Intraoperative anuria: An unusual cause. (22144941)
2011
5
Acute renal failure and anuria associated with vitamin D intoxication in two alpaca (Vicugna pacos) cria. (20102501)
2010
6
Giant vesical calculus presenting with azotaemia and anuria. (23132968)
2007
7
Bilateral pelvi-ureteric junction obstruction in a neonate presenting with sudden anuria. (18947670)
2006
8
Bilateral renal papillary necrosis due to Candida infection in a diabetic patient presenting as anuria. (14710985)
2003
9
An unusual case of neonatal anuria. (12657763)
2003
10
Obstructive anuria and dermatomyositis: a unique association. (9218037)
1997
11
Thrombotic occlusion of ureteric stent: an unusual cause of anuria after kidney transplantation. (9198067)
1997
12
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 39-1993. An 83-year-old woman with hypertension, sudden severe back pain, and anuria. (8366904)
1993
13
Neonatal anuria with maternal angiotensin-converting enzyme inhibition. (2761913)
1989
14
Surgical treatment of anuria caused by renal artery occlusion. Case report. (3445130)
1987
15
Reversal of postoperative anuria by decompressive celiotomy. (3156569)
1985
16
Bilateral ureteral obstruction causing anuria secondary to pregnancy. (7179634)
1982
17
Early anuria prevention in human kidney transplantation. Advantage of fluid load under pulmonary arterial pressure monitoring during surgical period. (388763)
1979
18
Anuria in infants and children. (671642)
1978
19
Sudden anuria in a pregnant woman with a solitary kidney. (717462)
1978
20
Anuria secondary to balloon catheters in children. (894813)
1977
21
Post-obstructive anuria: a documented entity. (765505)
1976
22
Phenacetin-induced renal papillary necrosis: pyonephros, anuria, and bilateral ureteral obstruction. (1136090)
1975
23
Letter: Transfusion reaction with anuria and uremia. (4772826)
1973
24
Management of ureteral injuries causing anuria. (5780602)
1969
25
Anuria secondary to ethylene glycol intoxication. (5796483)
1969
26
Anuria after kidney transplantation. (4874547)
1968
27
Transient anuria and paraplegia following traumatic rupture of the thoracic aorta. (5683697)
1968
28
Acute parenchymal dysfunction with acute anuria induced by retrograde pyelography. (6017689)
1967
29
CLINICO-PATHOLOGICAL CONFERENCE. ACUTE ABDOMINAL PAIN, BLOODY DIARRHEA AND ANURIA. (14076465)
1964
30
ARTIFICIAL KIDNEY IN THE TREATMENT OF ANURIA IN A 9-MONTH-OLD GIRL SUFFERING FROM ACUTE GLOMERULONEPHRITIS. (14135051)
1964
31
RECOVERY FROM ACUTE RENAL FAILURE AFTER 23 DAYS OF ANURIA. (14046664)
1963
32
The modern treatment of anuria and oliguria. (13591072)
1958
33
Anuria complicating the treatment of leukemia. (13582961)
1958
34
The use of caval catheterization in cases of severe oliguria and anuria. (13510678)
1957
35
Reflex anuria in the dog. (13304736)
1956
36
Anuria: report of a case, with discussion of therapy. (13153577)
1954
37
On the artificial kidney. XXIII. Casuistics of 14 cases of acute tubular nephritis (lower nephron nephrosis etc.) with anuria or severe oliguria of 4-28 days duration, treated conservatively and, on vital indication, with dialysis. (13113895)
1953
38
The electrolyte pattern in experimental anuria. (14924995)
1952
39
Acute anuria in rats; extracellular electrolyte studies following bilateral nephrectomy. (14924994)
1952
40
The management of anuria. (12980743)
1952
41
Correlation of renal function with the clinical course of anuria due to surgical complications. (12986654)
1952
42
Lower nephron nephrosis and the management of transfusion anuria. (14829722)
1951
43
Combined therapeutic measures in reversible anuria. (14803262)
1951
44
Experiences with anuria and oliguria. (14810352)
1951
45
Some experiences and problems in treating renal insufficiency: I. Extracorporeal dialysis of the blood in vivo in cases of uremia; 22 treatments on 18 cases. II. Fluid balance problems in cases of acute oliguria; anuria due to acute nephritis, incompatible blood transfusions lower-nephron nephrosis and so on i. a. illustrating the risks of excessive electrolyte-fluid supply and the i. a. illustrating the risks of the modern electrolyte; fluid therapy and the importance of continual weight control. (14782879)
1950
46
Anuria. (18127707)
1949
47
Anuria following ischaemia of the renal cortex. (18149306)
1949
48
Anuria; modern concepts of etiology and management. (18124951)
1949
49
A case of carbon tetrachloride poisoning with anuria treated by unilateral discission of the renal capsule. (18146596)
1949
50
Dietary and hormonal influences in experimental anuria. (18933523)
1948

Genetic Variations for Anuria

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Expression for genes affiliated with Anuria

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Anuria

Search GEO for disease gene expression data for Anuria.

Pathways for genes affiliated with Anuria

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Sources:
53Reactome, 12EMD Millipore, 49PharmGKB, 37NCBI BioSystems Database, 51QIAGEN
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Compounds for genes affiliated with Anuria

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Sources:
44Novoseek, 11DrugBank, 24HMDB, 28IUPHAR, 49PharmGKB, 59Tocris Bioscience, 2BitterDB
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Compounds related to Anuria according to GeneCards/GeneDecks:

(show top 50)    (show all 130)
idCompoundScoreTop Affiliating Genes
1norepinephrine44 11 2412.1MB, NR3C2
2captopril44 28 49 59 1114.1NR3C2, REN
3estradiol44 11 2412.0AGTR1, REN
4glycyrrhetinic acid44 2410.4NR3C2, REN, HSD11B2
5remikiren44 1110.4AGT, REN, ACE
6lacidipine449.4REN, ACE, AGTR1
7trandolapril44 1110.3ACE, REN, AGTR1
8pd12331944 2810.3AGTR1, ACE, AGT
9cilazapril44 1110.3REN, AGTR1, ACE
10inulin449.3REN, ALB, AGT
1111beta-hydroxysteroid449.2REN, HSD11B2, AGTR1, NR3C2
12indapamide44 1110.2ALB, REN, ACE
13doca449.2REN, NR3C2, HSD11B2
14aliskiren44 1110.2ACE, AGTR1, REN, AGT
15saralasin449.1AGTR1, AGT, ACE, REN
16enalaprilat449.1ACE, AGT, REN
17eprosartan44 28 1111.1ACE, AGTR1, AGT, REN
18benazepril44 1110.1AGT, REN, AGTR1, ACE
19olmesartan44 28 1111.1AGTR1, AGT, ACE, REN
20quinapril44 1110.1REN, ACE, AGTR1
21chymostatin449.1AGT, ACE, REN, AGTR1
22atenolol44 28 49 11 2413.1ACE, AGTR1, REN, AGT
23diltiazem44 28 1111.0REN, AGT, AGTR1, ACE
24eplerenone44 59 28 1112.0REN, ACE, NR3C2, AGTR1
25thiazide449.0AGTR1, NR3C2, REN, ACE
26glycyrrhizin44 2810.0NR3C2, HSD11B2, REN
27felodipine44 28 1111.0ACE, REN, NR3C2, AGTR1
28fosinopril44 1110.0REN, ALB, AGTR1, ACE
29ramipril44 119.9REN, ACE, ALB, AGTR1
30haloperidol44 28 2 49 1112.9MB, NR3C2, AGTR1, REN, AGT
31acth448.8AGT, AGTR1, NR3C2, REN, HSD11B2
32ang ii448.7ACE, REN, AGT, AGTR1, NR3C2
33furosemide44 49 59 28 11 2413.7ACE, REN, AGTR1, HSD11B2, ALB
34lisinopril44 11 2410.6AGT, ALB, ACE, AGTR1, REN
35valsartan44 59 28 1111.6AGT, REN, ALB, AGTR1, ACE
36perindopril44 49 1110.6AGTR1, ACE, ALB, REN, AGT
37telmisartan44 28 1110.6ALB, REN, AGT, ACE, AGTR1
38irbesartan44 28 49 1111.6ALB, ACE, REN, AGT, AGTR1
39candesartan44 28 1110.6REN, AGT, AGTR1, ALB, ACE
40enalapril44 49 1110.6AGT, ALB, ACE, AGTR1, REN
41amlodipine44 49 11 2411.6ACE, AGTR1, REN, ALB, AGT
42arginine448.3HSD11B2, AGT, NR3C2, MB, REN, AGTR1
43spironolactone49 44 59 28 1112.2HSD11B2, NR3C2, ALB, AGTR1, REN, ACE
44losartan44 49 28 1111.2ALB, NR3C2, AGTR1, ACE, REN, AGT
45hydrochlorothiazide44 49 28 11 2411.9NR3C2, HSD11B2, ACE, AGTR1, AGT, REN
46potassium44 11 249.8HSD11B2, NR3C2, ALB, ACE, REN, AGT
47sodium44 248.8REN, ALB, AGTR1, HSD11B2, AGT, ACE
48cholesterol44 28 11 2410.7ACE, ALB, NR3C2, HSD11B2, AGTR1, REN
49glucose447.6NR3C2, ACE, ALB, AGT, AGTR1, HSD11B2
50creatinine447.6ACE, HSD11B2, MB, NR3C2, AGTR1, REN

GO Terms for genes affiliated with Anuria

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16Gene Ontology
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Biological processes related to Anuria according to GeneCards/GeneDecks:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of NAD(P)H oxidase activityGO:03386410.0AGT, AGTR1
2regulation of blood vessel size by renin-angiotensinGO:00203410.0AGT, AGTR1
3regulation of renal sodium excretionGO:03581310.0AGTR1, AGT
4positive regulation of cholesterol esterificationGO:0108739.9AGT, AGTR1
5low-density lipoprotein particle remodelingGO:0343749.9AGTR1, AGT
6positive regulation of cellular protein metabolic processGO:0322709.8AGTR1, AGT
7positive regulation of macrophage derived foam cell differentiationGO:0107449.8AGT, AGTR1
8phospholipase C-activating G-protein coupled receptor signaling pathwayGO:0072009.8AGT, AGTR1
9regulation of renal output by angiotensinGO:0020199.7ACE, AGT
10regulation of systemic arterial blood pressure by renin-angiotensinGO:0030819.7ACE, AGTR1
11renin-angiotensin regulation of aldosterone productionGO:0020189.7REN, AGT, AGTR1
12positive regulation of reactive oxygen species metabolic processGO:20003799.7AGT, AGTR1
13regulation of vasodilationGO:0423129.7AGTR1, ACE
14regulation of vasoconstrictionGO:0192299.4AGTR1, AGT, ACE
15angiotensin maturationGO:0020039.4AGT, REN, ACE
16blood vessel remodelingGO:0019749.2ACE, AGT
17kidney developmentGO:0018229.0ACE, REN, AGT, AGTR1

Molecular functions related to Anuria according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1acetyltransferase activator activityGO:0106989.8AGT, AGTR1
2oxygen bindingGO:0198259.7ALB, MB
3bradykinin receptor bindingGO:0317119.4ACE, AGTR1
4steroid bindingGO:0054969.4NR3C2, HSD11B2

Products for genes affiliated with Anuria

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  • Antibodies
  • Proteins
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Sources for Anuria

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet