Aliases & Classifications for Anuria

MalaCards integrated aliases for Anuria:

Name: Anuria 12 51 41 14 69
Suppression of Urinary Secretion 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2983
MeSH 41 D001002
NCIt 46 C114699
UMLS 69 C0003460

Summaries for Anuria

MalaCards based summary : Anuria, also known as suppression of urinary secretion, is related to renal tubular dysgenesis and renal artery obstruction, and has symptoms including kidney problem, suppressed urine secretion and polyuria. An important gene associated with Anuria is ACE (Angiotensin I Converting Enzyme), and among its related pathways/superpathways are p70S6K Signaling and Peptide hormone metabolism. The drugs Epinephrine and Mannitol have been mentioned in the context of this disorder. Affiliated tissues include kidney, liver and uterus, and related phenotypes are behavior/neurological and cardiovascular system

Wikipedia : 72 Anuria, sometimes called anuresis, is nonpassage of urine, in practice is defined as passage of less... more...

Related Diseases for Anuria

Diseases related to Anuria via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 179)
# Related Disease Score Top Affiliating Genes
1 renal tubular dysgenesis 31.7 ACE AGT AGTR1 REN
2 renal artery obstruction 30.1 ACE REN
3 malignant hypertension 29.8 ACE AGT AGTR1 REN
4 pulmonary edema 29.8 ACE PIK3C2A REN
5 pyelonephritis 29.7 ACE ALB
6 posterior urethral valves 29.7 ACE AGT AGTR1
7 oligohydramnios 29.6 ACE AGT AGTR1 REN
8 compartment syndrome 29.1 ALB MB PIK3C2A
9 acute kidney tubular necrosis 29.0 ALB LRSAM1 MB
10 heart disease 28.1 ACE AGTR1 ALB NR3C2 PIK3C2A REN
11 myocardial infarction 27.0 ACE AGT AGTR1 ALB MB NR3C2
12 hyporeninemic hypoaldosteronism 10.5 ACE REN
13 pediatric hypertension 10.5 ACE AGT
14 hypertension, diastolic 10.5 ACE REN
15 hypoaldosteronism 10.4 ACE REN
16 atrial septal defect 4 10.4 ACE REN
17 hypertensive retinopathy 10.4 ACE REN
18 malignant essential hypertension 10.4 ACE REN
19 benign essential hypertension 10.4 ALB REN
20 congenital hepatic fibrosis 10.4 AGTR1 REN
21 kidney papillary necrosis 10.4 ALB REN
22 pure autonomic failure 10.3 ACE REN
23 syndrome of inappropriate antidiuretic hormone 10.3 ACE ALB
24 meningococcal infection 10.3 AGT AGTR1
25 ureteral disease 10.3 ACE REN
26 acute anterolateral myocardial infarction 10.3 ACE PIK3C2A
27 steroid inherited metabolic disorder 10.3 HSD11B2 REN
28 fiedler's myocarditis 10.3 ACE PIK3C2A
29 arthrogryposis, distal, type 3 10.3 NR3C2 REN
30 hepatic vascular disease 10.3 ALB REN
31 pseudohypoaldosteronism, type i, autosomal dominant 10.3 NR3C2 REN
32 idiopathic edema 10.2 ACE NR3C2
33 renal artery disease 10.2 ACE AGTR1 REN
34 systolic heart failure 10.2 ACE NR3C2
35 aortic valve disease 2 10.2 ACE AGT REN
36 renovascular hypertension 10.2 ACE AGTR1 REN
37 aortic coarctation 10.2 ACE AGT AGTR1
38 diastolic heart failure 10.2 ACE AGT AGTR1
39 orthostatic proteinuria 10.2 ACE ALB REN
40 intermittent claudication 10.2 ACE ALB
41 ischemic optic neuropathy 10.2 ACE AGT AGTR1
42 mitral valve disease 10.2 ACE AGT AGTR1
43 hepatorenal syndrome 10.2 ACE ALB REN
44 pseudohypoaldosteronism, type i, autosomal recessive 10.2 NR3C2 REN
45 anteroseptal myocardial infarction 10.2 ALB PIK3C2A
46 gitelman syndrome 10.2 AGT REN
47 vesicoureteral reflux 1 10.2 AGT AGTR1 REN
48 otosclerosis 10.2 ACE AGT AGTR1
49 glucose metabolism disease 10.2 ACE ALB REN
50 cerebrovascular disease 10.2 ACE AGTR1 REN

Graphical network of the top 20 diseases related to Anuria:



Diseases related to Anuria

Symptoms & Phenotypes for Anuria

UMLS symptoms related to Anuria:


kidney problem, suppressed urine secretion, polyuria, oliguria and anuria

MGI Mouse Phenotypes related to Anuria:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.97 AGT PIK3C2A AGTR1 REN HSD11B2 LRSAM1
2 cardiovascular system MP:0005385 9.92 PIK3C2A AGTR1 REN HSD11B2 MB ACE
3 homeostasis/metabolism MP:0005376 9.91 PIK3C2A AGTR1 REN ALB HSD11B2 MB
4 mortality/aging MP:0010768 9.81 PIK3C2A AGTR1 REN ALB HSD11B2 MB
5 muscle MP:0005369 9.43 AGT REN ALB HSD11B2 MB NR3C2
6 renal/urinary system MP:0005367 9.23 PIK3C2A AGTR1 REN ALB HSD11B2 ACE

Drugs & Therapeutics for Anuria

Drugs for Anuria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 26)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
2
Mannitol Approved, Investigational Phase 4 69-65-8 6251 453
3
Nitric Oxide Approved Phase 4 10102-43-9 145068
4
Prilocaine Approved Phase 4 721-50-6 4906
5 Racepinephrine Approved Phase 4 329-65-7
6 diuretics Phase 4
7 Epinephryl borate Phase 4
8 Natriuretic Agents Phase 4
9 Pharmaceutical Solutions Phase 4,Phase 1
10
Angiotensin II Approved, Investigational Phase 3 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
11
Irbesartan Approved, Investigational Phase 3 138402-11-6 3749
12 Angiotensin II Type 1 Receptor Blockers Phase 3
13 Angiotensin Receptor Antagonists Phase 3
14 Angiotensinogen Phase 3
15 Antihypertensive Agents Phase 3
16 Shiga Toxins Phase 1
17
Benazepril Approved, Investigational 86541-75-5 5362124
18
Benzocaine Approved, Investigational 1994-09-7, 94-09-7 2337
19
Valsartan Approved, Investigational 137862-53-4 60846
20 tannic acid Approved, Nutraceutical
21 Anesthetics
22 Adrenergic beta-Antagonists
23 Angiotensin-Converting Enzyme Inhibitors
24 HIV Protease Inhibitors
25
protease inhibitors
26 Dialysis Solutions

Interventional clinical trials:

(show all 17)

# Name Status NCT ID Phase Drugs
1 Early Continuous Renal Replacement Therapies (CRRT) in Patients With Severe Sepsis or Septic Shock With Acute Kidney Injury Unknown status NCT00837057 Phase 4
2 Control Of Fluid Balance Guided by Body Composition Monitoring in Patients on PeritoneAl dialySiS Unknown status NCT01887262 Phase 4
3 Randomized Controlled Trial Comparing Residual Kidney Function in Patients Undergoing Three or Four Exchanges CAPD Completed NCT01637792 Phase 4
4 Evaluation of Ureteral Patency in the Post-indigo Carmine Era Completed NCT02677623 Phase 4 Pyridium;Sodium Fluorescein;Mannitol
5 Saving Residual Renal Function Among Haemodialysis Patients Receiving Irbesartan Completed NCT00791830 Phase 3 Irbesartan;Placebo matching irbesartan 150 mg
6 Study to Evaluate the Safety and Efficacy of the Renal Assist Device in Patients With Acute Renal Failure Terminated NCT00280072 Phase 2
7 Shiga Toxin Producing Escherichia Coli (STEC) Volume Expansion Not yet recruiting NCT03275792 Phase 1 D5-0.9%NS;Routine home oral rehydration
8 Delayed or Direct Ureteroscopy in the Treatment of Pediatric Calcular Anuria Unknown status NCT02139059
9 Ureteral Stents Versus Percutaneous Nephrostomy for Initial Urinary Drainage Completed NCT02055430
10 Hemodialysis Frequency and the Calcification Propensity of Serum Completed NCT01975025
11 Artificial Kidney Initiation in Kidney Injury Completed NCT01932190
12 Renal Tubular Acidosis is Highly Prevalent in Critically Ill Patients Completed NCT02392091
13 The Intermittent Pneumoperitoneum Scheme of Work Breaks in Complex Laparoscopic Surgery Completed NCT01009372
14 Renal Protective Effects of Renin Angiotensin System (RAS) Inhibitor in Peritoneal Dialysis Patients Completed NCT00721773 Benazepril;Valsartan;Benazepril+Valsartan;Control
15 Myoglobin Removal by High Cut-off CVVHD Completed NCT01467180
16 The Artificial Kidney Initiation in Kidney Injury 2 Not yet recruiting NCT03396757
17 Intraoperative Anuric Episodes in Patients Undergoing Laparotomy Withdrawn NCT01703442

Search NIH Clinical Center for Anuria

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: anuria

Genetic Tests for Anuria

Anatomical Context for Anuria

MalaCards organs/tissues related to Anuria:

38
Kidney, Liver, Uterus, Heart, Cervix, Breast, Placenta

Publications for Anuria

Articles related to Anuria:

(show top 50) (show all 529)
# Title Authors Year
1
Re: Anuria Since Birth: Does it Impact Outcome of Kidney Transplant in Infants? ( 28093185 )
2017
2
A rare cause of anuria in a case of pre-B acute lymphoblastic leukaemia. ( 28566415 )
2017
3
An unusual cause of anuria in a young patient with hypertension. ( 29265069 )
2017
4
Case: Anuria and acute renal failure post-endoscopic valve ablation and Foley catheter insertion in a newborn with a small-capacity, non-compliant bladder. ( 29382462 )
2017
5
Total Anuria in an Infant with Rotavirus Gastroenteritis: Differential Diagnosis Between Bilaterally Obstructing Ammonium Acid Urate (AAU) Stones and Bilateral Papillary Necrosis. ( 29103248 )
2017
6
Anuria and acute kidney injury: an uncommon case of bilateral synchronous ureteric calculi. ( 27241565 )
2016
7
Anuria Secondary to Bilateral Obstructing Ureteral Stones in the Absence of Renal Colic. ( 27579429 )
2016
8
Anuria since birth: does it impact outcome of kidney transplant in infants? ( 27495879 )
2016
9
Point-of-Care Ultrasound to Assess Anuria in Children. ( 27490729 )
2016
10
Anuria after renal graft biopsy: Multidisciplinary intervention. ( 26857206 )
2016
11
Acute anuria after a family vacation to Corsica/France. ( 26852123 )
2016
12
Role of anuria in the relationship between indoxyl sulfate and anemia in peritoneal dialysis patients. ( 27932887 )
2016
13
Point-of-Care Ultrasound to Assess Anuria in Children. ( 27490730 )
2016
14
Duration of anuria predicts recovery of renal function after acute kidney injury requiring continuous renal replacement therapy. ( 26867084 )
2016
15
Quiz Page December 2016: Anuria on the Second Day Following Kidney Transplantation. ( 27884282 )
2016
16
Irreversible severe kidney injury and anuria in a 3-month-old girl with atypical haemolytic uraemic syndrome under administration of eculizumab. ( 26818219 )
2016
17
Unusual Causes of Abrupt Anuria Early Post-Renal Transplantation. ( 26246931 )
2015
18
Resolution of refractory hypotension and anuria in a premature newborn with loss-of-function of ACE. ( 26480306 )
2015
19
Resolution of refractory hypotension and anuria in a premature newborn with loss-of-function of ACE. ( 25899979 )
2015
20
Etiology and outcomes of anuria in acute kidney injury: a single center study. ( 26484014 )
2015
21
A successful pregnancy and parturition in a patient with anuria undergoing maintenance hemodialysis for 6 years: a case report of a 3-year-follow-up. ( 26370296 )
2015
22
Focal segmental glomerular sclerosis recurrence with massive proteinuria and anuria immediately after kidney transplantation. ( 26031597 )
2015
23
A rare cause of anuria: Bilateral synchronous isolated mid-ureteric tubercular lesions. ( 26604451 )
2015
24
Recovery of renal function after prolonged anuria in acute suprarenal aortic occlusion. ( 26520421 )
2015
25
Subcapsular Hematoma Causing Anuria After Renal Graft Trauma. ( 26496471 )
2015
26
Reflex anuria: a rare complication of prophylactic ureteral catheterization. ( 25943463 )
2015
27
Recurrent clot anuria following laparoscopic pyeloplasty in a solitary functioning kidney: managing with double guide wire technique. ( 25540210 )
2014
28
Reflex anuria: a rare cause of acute kidney injury. ( 24765255 )
2014
29
Management of calculus anuria using ureteroscopic lithotripsy as a first line treatment: its efficacy and safety. ( 24807749 )
2014
30
Perioperative Anuria Resulting in the Diagnosis of Infrasphincteric Ectopic Ureter in an Adult Female. ( 26955562 )
2014
31
Ureteric stents vs percutaneous nephrostomy for initial urinary drainage in children with obstructive anuria and acute renal failure due to ureteric calculi: a prospective, randomised study. ( 24698195 )
2014
32
Quiz page June 2014: a 45-year-old woman with acute anuria. ( 24856622 )
2014
33
Management of obstructive calcular anuria with acute renal failure in children less than 4 years in age: A protocol for initial urinary drainage in relation to planned definitive stone management. ( 24953544 )
2014
34
Successful management of repetitive urinary obstruction and anuria caused by double j stent calculi formation after renal transplantation. ( 25110605 )
2014
35
Anuria in a solitary kidney with Candida bezoars managed conservatively. ( 24213483 )
2013
36
Reflex anuria: an old concept with new evidence. ( 23979816 )
2013
37
Renal recoverability in infants with obstructive calcular anuria: is it better than in older children? ( 23769201 )
2013
38
Anuria due to inadvertent prostatectomy during cryptorchidectomy. ( 24155461 )
2013
39
Reflex anuria following acute cardiac event. ( 23688052 )
2013
40
Anuria and abdominal pain induced by ceftriaxone-associated ureterolithiasis in adults. ( 23180444 )
2013
41
Family recurrence and oligo-anuria predict uremic restless legs syndrome. ( 21824115 )
2012
42
Autologous creatinine clearance in a case of necrotizing fasciitis and anuria. ( 22343604 )
2012
43
Reflux anuria after prophylactic ureteral catheter removal: a case description and review of the literature. ( 22192094 )
2012
44
Assessment of recoverability of kidney function in children with obstructive calcular anuria: multicenter study. ( 21527220 )
2011
45
Atypical hemolytic-uremic syndrome (HUS) with recovery after a long-lasting anuria: a case report. ( 21607045 )
2011
46
An unusual cause of anuria and hydronephrosis in a 12-year-old girl. ( 21463179 )
2011
47
Unusual cause of postrenal biopsy anuria in a renal transplant patient. ( 21326078 )
2011
48
Investigating the mechanism for maintaining eucalcemia despite immobility and anuria in the hibernating American black bear (Ursus americanus). ( 21893223 )
2011
49
Anuria in a 9-month-old infant resulting from ureteral cystine stones. ( 22025963 )
2011
50
Reflex anuria. ( 21884352 )
2011

Variations for Anuria

Expression for Anuria

Search GEO for disease gene expression data for Anuria.

Pathways for Anuria

GO Terms for Anuria

Biological processes related to Anuria according to GeneCards Suite gene sharing:

(show all 21)
# Name GO ID Score Top Affiliating Genes
1 regulation of blood pressure GO:0008217 9.67 ACE AGT REN
2 protein catabolic process GO:0030163 9.6 LRSAM1 REN
3 positive regulation of protein tyrosine kinase activity GO:0061098 9.59 ACE AGT
4 blood vessel remodeling GO:0001974 9.58 ACE AGT
5 positive regulation of reactive oxygen species metabolic process GO:2000379 9.58 AGT AGTR1
6 positive regulation of cellular protein metabolic process GO:0032270 9.57 AGT AGTR1
7 positive regulation of macrophage derived foam cell differentiation GO:0010744 9.56 AGT AGTR1
8 kidney development GO:0001822 9.56 ACE AGT AGTR1 REN
9 amyloid-beta metabolic process GO:0050435 9.55 ACE REN
10 regulation of blood vessel diameter GO:0097746 9.54 ACE AGTR1
11 low-density lipoprotein particle remodeling GO:0034374 9.52 AGT AGTR1
12 positive regulation of cholesterol esterification GO:0010873 9.51 AGT AGTR1
13 regulation of vasoconstriction GO:0019229 9.5 ACE AGT AGTR1
14 positive regulation of NAD(P)H oxidase activity GO:0033864 9.48 AGT AGTR1
15 regulation of blood vessel diameter by renin-angiotensin GO:0002034 9.46 AGT AGTR1
16 regulation of blood volume by renin-angiotensin GO:0002016 9.43 AGT REN
17 regulation of renal sodium excretion GO:0035813 9.4 AGT AGTR1
18 regulation of renal output by angiotensin GO:0002019 9.37 ACE AGT
19 angiotensin maturation GO:0002003 9.33 ACE AGT REN
20 regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9.13 ACE AGT AGTR1
21 renin-angiotensin regulation of aldosterone production GO:0002018 8.8 AGT AGTR1 REN

Molecular functions related to Anuria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxygen binding GO:0019825 9.16 ALB MB
2 steroid binding GO:0005496 8.96 HSD11B2 NR3C2
3 bradykinin receptor binding GO:0031711 8.62 ACE AGTR1

Sources for Anuria

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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